US4894366A
(en)
*
|
1984-12-03 |
1990-01-16 |
Fujisawa Pharmaceutical Company, Ltd. |
Tricyclo compounds, a process for their production and a pharmaceutical composition containing the same
|
US5266692A
(en)
*
|
1984-12-03 |
1993-11-30 |
Fujisawa Pharmaceutical Co., Ltd. |
Tricyclo compounds, a process for their production and a pharmaceutical composition containing the same
|
US5254562A
(en)
*
|
1984-12-03 |
1993-10-19 |
Fujisawa Pharmaceutical Company, Ltd. |
Tricyclo compounds, a process for their production and a pharmaceutical composition containing the same
|
GB8608080D0
(en)
*
|
1986-04-02 |
1986-05-08 |
Fujisawa Pharmaceutical Co |
Solid dispersion composition
|
ES2060621T3
(es)
*
|
1987-06-05 |
1994-12-01 |
Fujisawa Pharmaceutical Co |
Anticuerpos anti-sustancia fr-900506 y metodo de inmunoensayo enzimatico altamente sensible.
|
DE3737523A1
(de)
*
|
1987-11-05 |
1989-05-18 |
Bayer Ag |
Verwendung von substituierten hydroxypiperidinen als antivirale mittel
|
AT400808B
(de)
*
|
1987-11-09 |
1996-03-25 |
Sandoz Ag |
Verwendung von tricyclischen verbindungen zur herstellung von topischen arzneimitteln
|
DE3844904C2
(de)
*
|
1987-11-09 |
1997-01-30 |
Sandoz Ag |
Neue Verwendung von 11,28-Dioxa-4-azatricyclo-[22.3.1.0·4·,·9·]octacos-18-en-Derivaten
|
US5366971A
(en)
*
|
1987-11-09 |
1994-11-22 |
Sandoz Ltd. |
Use of 11,28-dioxa-4-azatricyclo[22.3.1.04,9 ]octacos-18-ene derivatives and pharmaceutical compositions containing them
|
PH26083A
(en)
*
|
1987-11-09 |
1992-02-06 |
Sandoz Ltd |
11, 28-dioxa-4-azatricyclo [22.3.1.04.9) octacos-18-ene derivatives and pharmaceutical compositions containing them and method of use thereof
|
DE3838035C2
(de)
*
|
1987-11-09 |
1994-03-24 |
Sandoz Ag |
Neue Verwendung von 11,28-dioxa-4-azatricyclo[22.3.1.O·4··,··9·]octacos-18-en-Derivaten
|
GB8728820D0
(en)
*
|
1987-12-09 |
1988-01-27 |
Fisons Plc |
Compounds
|
EP0346427B1
(en)
|
1987-12-09 |
1995-03-29 |
FISONS plc |
Macrocyclic compounds
|
AT407957B
(de)
*
|
1987-12-17 |
2001-07-25 |
Novartis Erfind Verwalt Gmbh |
Neue verwendung von 11,28-dioxa-4-azatricyclo- (22.3.1.04,9)octacos-18-en-derivaten und sie enthaltende pharmazeutische zubereitungen
|
EP0323865A1
(en)
*
|
1988-01-07 |
1989-07-12 |
Merck & Co. Inc. |
Novel immunosuppressant agent
|
US5290772A
(en)
*
|
1988-06-29 |
1994-03-01 |
Merck & Co., Inc. |
Immunosuppressant agent
|
US4981792A
(en)
*
|
1988-06-29 |
1991-01-01 |
Merck & Co., Inc. |
Immunosuppressant compound
|
EP0349061B1
(en)
*
|
1988-06-29 |
1995-03-29 |
Merck & Co. Inc. |
Immunosuppressant agent
|
EP0353678B1
(en)
*
|
1988-08-01 |
1995-12-13 |
Fujisawa Pharmaceutical Co., Ltd. |
FR-901154 and FR-901155 substances, a process for their production
|
US5202258A
(en)
*
|
1988-08-05 |
1993-04-13 |
Merck & Co., Inc. |
Immunosuppressant-producing culture
|
EP0356399A3
(en)
*
|
1988-08-26 |
1991-03-20 |
Sandoz Ag |
Substituted 4-azatricyclo (22.3.1.04.9) octacos-18-ene derivatives, their preparation and pharmaceutical compositions containing them
|
EP0358508A3
(en)
*
|
1988-09-08 |
1991-03-20 |
Merck & Co. Inc. |
Novel immunosuppressant compound
|
US4980466A
(en)
*
|
1988-10-12 |
1990-12-25 |
Merck & Co., Inc. |
Hydroxide mediated FK-506 rearrangement product
|
DE68904037T2
(de)
*
|
1988-10-12 |
1993-06-03 |
Merck & Co Inc |
Verfahren zur umlagerung von fk-506 unter beteiligung von hydroxid.
|
CA1316916C
(en)
*
|
1988-10-12 |
1993-04-27 |
David Askin |
Hydroxide mediated fk-506 rearrangement product
|
CH678855A5
(fi)
*
|
1988-11-29 |
1991-11-15 |
Sandoz Ag |
|
EP0378320A3
(en)
*
|
1989-01-13 |
1990-11-28 |
Merck & Co. Inc. |
Microbial transformation product
|
US4975372A
(en)
*
|
1989-01-13 |
1990-12-04 |
Merck & Co., Inc. |
Microbial transformation product of L-683,590
|
US5268370A
(en)
*
|
1989-01-13 |
1993-12-07 |
Merck & Co., Inc. |
Microbial transformation product of L-679,934
|
EP0378317A3
(en)
*
|
1989-01-13 |
1990-11-28 |
Merck & Co. Inc. |
Microbial transformation product of l-679,934
|
EP0388152B1
(en)
*
|
1989-03-15 |
1994-10-12 |
Merck & Co. Inc. |
Process for producing an immunosuppressant agent (demethimmunomycin) using a mutant strain of a microorganism
|
US5272068A
(en)
*
|
1989-03-15 |
1993-12-21 |
Merck & Co., Inc. |
Process for producing immunosuppressant agent L-683942 by fermentation
|
DE69015393T2
(de)
*
|
1989-03-15 |
1995-06-01 |
Merck & Co Inc |
Immunosuppressives Mittel.
|
US5155228A
(en)
*
|
1989-03-23 |
1992-10-13 |
Merck & Co., Inc. |
FK-506 C10-C18 process intermediates
|
US4940797A
(en)
*
|
1989-03-23 |
1990-07-10 |
Merck & Co., Inc. |
Process for synthesis of FK-506 C10-C18 intermediates
|
US5057608A
(en)
*
|
1989-04-21 |
1991-10-15 |
Merck & Co., Inc. |
Immunoregulants, immunosuppressants, process to make ring expanded macrolide related to FK-506/FK-520
|
US5068323A
(en)
*
|
1989-04-21 |
1991-11-26 |
Merck & Co., Inc. |
Thermally re-arranged FK-506 derivatives having immunosuppressant activity
|
EP0399579A1
(en)
*
|
1989-04-21 |
1990-11-28 |
Merck & Co. Inc. |
Macrolides having immunosuppressive activity
|
EP0396400A1
(en)
*
|
1989-05-05 |
1990-11-07 |
Merck & Co. Inc. |
Microbial transformation product
|
US5270187A
(en)
*
|
1989-05-05 |
1993-12-14 |
Merck & Co., Inc. |
Microbial transformation product
|
US4987139A
(en)
*
|
1989-05-05 |
1991-01-22 |
Merck & Co., Inc. |
FK-520 microbial transformation product
|
IE64214B1
(en)
*
|
1989-06-06 |
1995-07-26 |
Fujisawa Pharmaceutical Co |
Macrolides for the treatment of reversible obstructive airways diseases
|
US5138052A
(en)
*
|
1989-06-13 |
1992-08-11 |
Merck & Co., Inc. |
L-683,590 microbial transformation product
|
CA2018710A1
(en)
*
|
1989-06-13 |
1990-12-13 |
Shieh-Shung T. Chen |
L-683,590 microbial transformation product
|
CA2032159A1
(en)
*
|
1989-06-14 |
1990-12-15 |
Andrew J. F. Edmunds |
Heteroatoms-containing tricyclic compounds
|
US5235066A
(en)
*
|
1989-06-30 |
1993-08-10 |
Merck & Co., Inc. |
FK-506 type macrolide intermediate
|
US5164525A
(en)
*
|
1989-06-30 |
1992-11-17 |
Merck & Co., Inc. |
Synthetic process for fk-506 type macrolide intermediates
|
EP0413532A3
(en)
*
|
1989-08-18 |
1991-05-15 |
Fisons Plc |
Macrocyclic compounds
|
EP0487593A1
(en)
*
|
1989-08-18 |
1992-06-03 |
FISONS plc |
Macrocyclic compounds
|
US5011943A
(en)
*
|
1989-08-28 |
1991-04-30 |
Merck Frosst Canada, Inc. |
FK-506 C10 -C24 process intermediates
|
GR1001225B
(el)
*
|
1989-09-14 |
1993-06-30 |
Fisons Plc |
Νέαι μακροκυκλικαί ενώσεις και νέα μέ?οδος χρήσεως τους.
|
US5215995A
(en)
*
|
1989-10-16 |
1993-06-01 |
Fujisawa Pharmaceutical Co., Ltd. |
Hair revitalizing agent
|
ATE126803T1
(de)
*
|
1989-11-09 |
1995-09-15 |
Sandoz Ag |
Heteroatome enthaltende tricyclische verbindungen.
|
IE904050A1
(en)
*
|
1989-11-13 |
1991-05-22 |
Merck & Co Inc |
Aminomacrolides and derivatives having immunosuppressive¹activity
|
US5208228A
(en)
*
|
1989-11-13 |
1993-05-04 |
Merck & Co., Inc. |
Aminomacrolides and derivatives having immunosuppressive activity
|
GB8925797D0
(en)
*
|
1989-11-15 |
1990-01-04 |
Fisons Plc |
Compositions
|
EP0444829A3
(en)
*
|
1990-02-27 |
1992-06-03 |
Fisons Plc |
Immunosuppressive compounds
|
US5260301A
(en)
*
|
1990-03-01 |
1993-11-09 |
Fujisawa Pharmaceutical Co., Ltd. |
Pharmaceutical solution containing FK-506
|
US5064835A
(en)
*
|
1990-03-01 |
1991-11-12 |
Merck & Co., Inc. |
Hydroxymacrolide derivatives having immunosuppressive activity
|
WO1991013899A1
(en)
*
|
1990-03-12 |
1991-09-19 |
Fujisawa Pharmaceutical Co., Ltd. |
Tricyclo compounds
|
US5296489A
(en)
*
|
1990-03-13 |
1994-03-22 |
Fisons |
Immunosuppressive macrocyclic compounds
|
IE910847A1
(en)
*
|
1990-03-13 |
1991-09-25 |
Fisons Plc |
Immunosuppressive macrocyclic compounds
|
CA2040551A1
(en)
*
|
1990-04-30 |
1991-10-31 |
Mark T. Goulet |
Deoxymacrolide derivatives having immunosuppressive activity
|
WO1991017754A1
(en)
*
|
1990-05-11 |
1991-11-28 |
Fujisawa Pharmaceutical Co., Ltd. |
Methods for treating and preventing inflammation of mucosa and blood vessels using fk 506 and related compounds
|
WO1991019495A1
(en)
*
|
1990-06-11 |
1991-12-26 |
Fujisawa Pharmaceutical Co., Ltd. |
Use of a macrolide compound such as fk 506 for manufacturing a medicament for treating idiopathic thrombocytopenic purpura and basedow's disease
|
US5643901A
(en)
*
|
1990-06-11 |
1997-07-01 |
Fujisawa Pharmaceutical Co., Ltd. |
Medicament for treating idiopathic thrombocytopenic purpura
|
CA2044846A1
(en)
*
|
1990-06-25 |
1991-12-26 |
Thomas R. Beattie |
Antagonists of immunosuppressive macrolides
|
US5342935A
(en)
*
|
1990-06-25 |
1994-08-30 |
Merck & Co., Inc. |
Antagonists of immunosuppressive macrolides
|
GB9014136D0
(en)
*
|
1990-06-25 |
1990-08-15 |
Fujisawa Pharmaceutical Co |
Tricyclo compounds,a process for their production and a pharmaceutical composition containing the same
|
US5210030A
(en)
*
|
1990-06-25 |
1993-05-11 |
Merck & Co., Inc. |
Process for selectively acylating immunomycin
|
US5190950A
(en)
*
|
1990-06-25 |
1993-03-02 |
Merck & Co., Inc. |
Antagonists of immunosuppressive macrolides
|
GB9014681D0
(en)
*
|
1990-07-02 |
1990-08-22 |
Fujisawa Pharmaceutical Co |
Tricyclo compounds,a process for their production and a pharmaceutical composition containing the same
|
MY110418A
(en)
*
|
1990-07-02 |
1998-05-30 |
Novartis Ag |
Heteroatoms-containing tricyclic compounds.
|
EP0466365A3
(en)
*
|
1990-07-03 |
1992-04-15 |
Merck & Co. Inc. |
Novel immunosuppressant fermentation products of a microorganism
|
GB2245891A
(en)
*
|
1990-07-09 |
1992-01-15 |
Fujisawa Pharmaceutical Co |
Tricyclo compounds
|
GB2246350A
(en)
*
|
1990-07-23 |
1992-01-29 |
Fujisawa Pharmaceutical Co |
Tricyclo compounds
|
US5089517A
(en)
*
|
1990-08-03 |
1992-02-18 |
The Board Of Trustees Of The Leland Stanford Junior University |
Neuroprotection by indolactam v and derivatives thereof
|
US5384316A
(en)
*
|
1990-08-18 |
1995-01-24 |
Fisons Plc |
4,16-diazatetracyclo[23.3.1.1.Hu 14,17=b . 0 Hu 4,9 triaconta-16,19-diene-2,3,10-trione derivatives
|
GB2247620A
(en)
*
|
1990-09-07 |
1992-03-11 |
Fujisawa Pharmaceutical Co |
The use of macrolide compounds for cytomegalovirus infection
|
CA2051872A1
(en)
*
|
1990-09-24 |
1992-03-25 |
Kevin M. Byrne |
Directed biosynthesis process for prolyl-immunomycin
|
GB2248184A
(en)
*
|
1990-09-28 |
1992-04-01 |
Fujisawa Pharmaceutical Co |
New use of macrolide compounds for active oxygen-mediated diseases
|
US5143918A
(en)
*
|
1990-10-11 |
1992-09-01 |
Merck & Co., Inc. |
Halomacrolides and derivatives having immunosuppressive activity
|
US5233036A
(en)
*
|
1990-10-16 |
1993-08-03 |
American Home Products Corporation |
Rapamycin alkoxyesters
|
US5348966A
(en)
*
|
1990-10-24 |
1994-09-20 |
Fujisawa Pharmaceutical Co., Ltd. |
Method for treating pyoderma and Sezary's syndrome using FK 506 and related compounds
|
CA2054128A1
(en)
*
|
1990-10-29 |
1992-04-30 |
Kevin M. Byrne |
Process for the production of analogues of immunomycin
|
PH31204A
(en)
*
|
1990-11-02 |
1998-05-05 |
Fujisawa Pharmaceutical Co |
Pharmaceutical composition.
|
CA2054983A1
(en)
*
|
1990-11-08 |
1992-05-09 |
Sotoo Asakura |
Suspendible composition and process for preparing the same
|
GB2249787A
(en)
*
|
1990-11-19 |
1992-05-20 |
Fujisawa Pharmaceutical Co |
Lactone compounds
|
GB9027471D0
(en)
*
|
1990-12-19 |
1991-02-06 |
Fujisawa Pharmaceutical Co |
Novel compound
|
US5194378A
(en)
*
|
1991-01-28 |
1993-03-16 |
Merck & Co., Inc. |
Process for producing fk-506
|
US5116756A
(en)
*
|
1991-01-28 |
1992-05-26 |
Merck & Co., Inc. |
Process for producing FK-506
|
WO1992013862A1
(en)
*
|
1991-02-05 |
1992-08-20 |
Fujisawa Pharmaceutical Co., Ltd. |
Lactone compounds
|
US5147877A
(en)
*
|
1991-04-18 |
1992-09-15 |
Merck & Co. Inc. |
Semi-synthetic immunosuppressive macrolides
|
WO1992019278A1
(en)
*
|
1991-04-26 |
1992-11-12 |
Kurume University |
Use of macrolide compounds for eye diseases
|
US5162334A
(en)
*
|
1991-05-13 |
1992-11-10 |
Merck & Co., Inc. |
Amino O-alkyl, O-alkenyl and O-alkynlmacrolides having immunosuppressive activity
|
US5262533A
(en)
*
|
1991-05-13 |
1993-11-16 |
Merck & Co., Inc. |
Amino O-aryl macrolides having immunosuppressive activity
|
US5250678A
(en)
*
|
1991-05-13 |
1993-10-05 |
Merck & Co., Inc. |
O-aryl, O-alkyl, O-alkenyl and O-alkynylmacrolides having immunosuppressive activity
|
US5565560A
(en)
*
|
1991-05-13 |
1996-10-15 |
Merck & Co., Inc. |
O-Aryl,O-alkyl,O-alkenyl and O-alkynylmacrolides having immunosuppressive activity
|
EP0528452A1
(en)
*
|
1991-06-19 |
1993-02-24 |
Merck & Co. Inc. |
Immunomycin enzymatic and/or microbial methylation products
|
US5225403A
(en)
*
|
1991-06-25 |
1993-07-06 |
Merck & Co., Inc. |
C-21 hydroxylated FK-506 antagonist
|
US5198358A
(en)
*
|
1991-08-28 |
1993-03-30 |
Merck & Co., Inc. |
Microorganism for producing C-31 desmethyl FR-900520 cyclic hemiketal immunosuppressant agent
|
US5149701A
(en)
*
|
1991-08-01 |
1992-09-22 |
Merck & Co., Inc. |
C-31 methylated FR-900520 cyclic hemiketal immunosuppressant agents
|
US5273979A
(en)
*
|
1991-08-01 |
1993-12-28 |
Merck & Co., Inc. |
C-31 desmethyl FR-900520 cyclic hemiketal immunosuppressant agent
|
US5189042A
(en)
*
|
1991-08-22 |
1993-02-23 |
Merck & Co. Inc. |
Fluoromacrolides having immunosuppressive activity
|
AU2580492A
(en)
*
|
1991-09-05 |
1993-04-05 |
Abbott Laboratories |
Macrocyclic immunomodulators
|
US5708002A
(en)
*
|
1991-09-05 |
1998-01-13 |
Abbott Laboratories |
Macrocyclic immunomodulators
|
US5247076A
(en)
*
|
1991-09-09 |
1993-09-21 |
Merck & Co., Inc. |
Imidazolidyl macrolides having immunosuppressive activity
|
ZA926812B
(en)
|
1991-09-09 |
1993-04-28 |
Merck & Co Inc |
O-heteroaryl,o-alkylheteroaryl,o-alkenylheteroaryl and o-alkynylheteroaryl macrolides having immunosupressive activity
|
US5252732A
(en)
*
|
1991-09-09 |
1993-10-12 |
Merck & Co., Inc. |
D-heteroaryl, O-alkylheteroaryl, O-alkenylheteroaryl and O-alkynylheteroarylmacrolides having immunosuppressive activity
|
US5208241A
(en)
*
|
1991-09-09 |
1993-05-04 |
Merck & Co., Inc. |
N-heteroaryl, n-alkylheteroaryl, n-alkenylheteroaryl and n-alkynylheteroarylmacrolides having immunosuppressive activity
|
US5164495A
(en)
*
|
1991-09-18 |
1992-11-17 |
Abbott Laboratories |
Method for preparing a dicarboxylic acid half-acid ester of FK506
|
US5221625A
(en)
*
|
1992-01-10 |
1993-06-22 |
Merck & Co., Inc. |
Cyclcic FR-900520 microbial biotransformation agent
|
AU665052B2
(en)
*
|
1992-01-28 |
1995-12-14 |
Abraham Karpas |
The use of a compound for the manufacture of a medicament for the treatment of HIV infection
|
JP3140228B2
(ja)
*
|
1992-02-17 |
2001-03-05 |
ファイザー製薬株式会社 |
新規な大環状ラクトンおよびその生産菌
|
WO1993018049A1
(en)
*
|
1992-03-02 |
1993-09-16 |
Pfizer Inc. |
Fluorosugar derivatives of macrolides
|
CA2131372C
(en)
*
|
1992-03-02 |
1998-07-14 |
Kevin Koch |
Sugar derivatives of macrolides
|
WO1993018048A1
(en)
*
|
1992-03-02 |
1993-09-16 |
Pfizer, Inc. |
2-aminosugar derivatives of macrolides
|
JPH07500613A
(ja)
*
|
1992-03-02 |
1995-01-19 |
ファイザー・インコーポレーテッド |
免疫抑制剤及び抗真菌剤としてのマクロライドのデソサミノ誘導体
|
EP0562853B1
(en)
|
1992-03-27 |
1996-06-05 |
American Home Products Corporation |
29-Demethoxyrapamycin for inducing immunosuppression
|
CA2091194A1
(en)
*
|
1992-04-08 |
1993-10-09 |
Richard D. Connell |
2-oxo-ethyl derivatives as immunosuppressants
|
HUT66531A
(en)
*
|
1992-05-07 |
1994-12-28 |
Sandoz Ag |
Heteroatoms-containing tricyclic compounds, pharmaceutical prepns contg. them and process for producing them
|
WO1993025533A1
(en)
*
|
1992-06-05 |
1993-12-23 |
Abbott Laboratories |
Methods and reagents for the determination of immunosuppressive agents
|
US5284877A
(en)
*
|
1992-06-12 |
1994-02-08 |
Merck & Co., Inc. |
Alkyl and alkenyl macrolides having immunosuppressive activity
|
US5284840A
(en)
*
|
1992-06-12 |
1994-02-08 |
Merck & Co., Inc. |
Alkylidene macrolides having immunosuppressive activity
|
US5264355A
(en)
*
|
1992-07-02 |
1993-11-23 |
Merck & Co., Inc. |
Methlating enzyme from streptomyces MA6858
|
ZA935112B
(en)
*
|
1992-07-17 |
1994-02-08 |
Smithkline Beecham Corp |
Rapamycin derivatives
|
US5324644A
(en)
*
|
1992-07-28 |
1994-06-28 |
Merck & Co., Inc. |
Process for producing immunosuppressant agent
|
DE69331585T2
(de)
*
|
1992-08-12 |
2002-08-08 |
Fujisawa Pharmaceutical Co., Ltd. |
Monoklonaler antikörper spezifisch für das fk-506-bindende protein, methode zur bestimmung des gehaltes an fk-506-bindendem protein in einer probe und reagenzsatz dafür
|
US5365948A
(en)
*
|
1992-08-21 |
1994-11-22 |
J & W Mcmichael Software Inc. |
Method for use in treating a patient with FK 506 to prevent an adverse immune response
|
US5283183A
(en)
*
|
1992-09-28 |
1994-02-01 |
Merck & Co., Inc. |
Cyclic FR-900520 microbial biotransformation agent
|
US5290689A
(en)
*
|
1992-09-28 |
1994-03-01 |
Merck & Co., Inc. |
New cyclic FR-900520 microbial biotransformation agent
|
US5268281A
(en)
*
|
1992-09-28 |
1993-12-07 |
Merck & Co., Inc. |
Cyclic FR-900520 microbial biotransformation agent
|
US5268282A
(en)
*
|
1992-09-28 |
1993-12-07 |
Merck & Co., Inc. |
Cyclic FR-900520 microbial biotransformation agent
|
US5318895A
(en)
*
|
1992-10-05 |
1994-06-07 |
Merck & Co., Inc. |
Aspergillus niger mutants
|
GB9227055D0
(en)
*
|
1992-12-29 |
1993-02-24 |
Fujisawa Pharmaceutical Co |
New use
|
DE4300478C2
(de)
*
|
1993-01-11 |
1998-05-20 |
Eos Electro Optical Syst |
Verfahren und Vorrichtung zum Herstellen eines dreidimensionalen Objekts
|
JPH08507788A
(ja)
*
|
1993-03-17 |
1996-08-20 |
アボツト・ラボラトリーズ |
置換脂環式アミン含有大環状免疫調節剤
|
CH686761A5
(de)
|
1993-05-27 |
1996-06-28 |
Sandoz Ag |
Galenische Formulierungen.
|
AT408520B
(de)
*
|
1993-05-27 |
2001-12-27 |
Novartis Erfind Verwalt Gmbh |
Galenische formulierungen
|
MY110603A
(en)
*
|
1993-05-27 |
1998-08-29 |
Novartis Ag |
Tetrahydropyran derivatives
|
GB2279006A
(en)
*
|
1993-06-03 |
1994-12-21 |
Fujisawa Pharmaceutical Co |
Treatment of amyotrophic lateral sclerosis
|
JPH06345646A
(ja)
*
|
1993-06-08 |
1994-12-20 |
Fujisawa Pharmaceut Co Ltd |
ローション剤
|
US5352783A
(en)
*
|
1993-06-09 |
1994-10-04 |
Merck & Co., Inc. |
Microbial transformation product having immunosuppressive activity
|
US5359060A
(en)
*
|
1993-07-06 |
1994-10-25 |
Pfizer, Inc. |
Phosponated derivatives of macrolides
|
EP0711298A1
(en)
*
|
1993-07-30 |
1996-05-15 |
Abbott Laboratories |
Activated macrolactams having immunomodulatory activities
|
GB2281294A
(en)
*
|
1993-08-23 |
1995-03-01 |
Fujisawa Pharmaceutical Co |
Process for producing half esters of the macrolide FK506
|
US5616588A
(en)
|
1993-09-30 |
1997-04-01 |
American Home Products Corporation |
Rapamycin formulation for IV injection
|
UA41884C2
(uk)
*
|
1993-11-05 |
2001-10-15 |
Амерікан Хоум Продактс Корпорейшн |
Спосіб відокремлення рапаміцину від кислотних, основних та неполярних нейтральних домішок, присутніх в концентраті екстрактів ферментаційного бульйону або маточних розчинів
|
US5898029A
(en)
*
|
1994-04-12 |
1999-04-27 |
The John Hopkins University |
Direct influences on nerve growth of agents that interact with immunophilins in combination with neurotrophic factors
|
US5880280A
(en)
*
|
1994-06-15 |
1999-03-09 |
Merck & Co., Inc. |
Aryl, alkyl, alkenyl and alkynylmacrolides having immunosuppressive activity
|
US5693648A
(en)
*
|
1994-09-30 |
1997-12-02 |
Merck & Co., Inc. |
O-aryl, O-alkyl, O-alkenyl and O-alkynyl-macrolides having immunosuppressive activity
|
NZ331824A
(en)
|
1994-10-26 |
2000-01-28 |
Novartis Ag |
use of an unsaturated fatty alcohol to stabilise a macrolide in a pharmaceutical composition
|
AR004480A1
(es)
*
|
1995-04-06 |
1998-12-16 |
Amico Derin C D |
Compuestos de ascomicina que poseen actividad antiinflamatoria, pro cedimiento para prepararlos, uso de dichos compuestos para preparar agentesfarmaceuticos y composiciones farmaceuticas que los incluyen
|
US5616595A
(en)
*
|
1995-06-07 |
1997-04-01 |
Abbott Laboratories |
Process for recovering water insoluble compounds from a fermentation broth
|
DE69630798T2
(de)
*
|
1995-09-19 |
2004-09-23 |
Fujisawa Pharmaceutical Co., Ltd. |
Aerosolzusammensetzungen
|
SI1208847T1
(sl)
|
1996-07-30 |
2007-06-30 |
Novartis Ag |
Farmacevtski sestavki za zdravljenje stanj zavračanja transplantatov in avtoimunskih ali vnetnih stanj
|
KR100244164B1
(ko)
*
|
1997-07-15 |
2000-03-02 |
김용옥 |
수용성 고분자-타크로리무스 접합체 화합물 및 그의 제조 방법
|
US6562620B2
(en)
*
|
1997-09-19 |
2003-05-13 |
Mcgill University |
Medium to promote islet cell survival
|
US6890546B2
(en)
|
1998-09-24 |
2005-05-10 |
Abbott Laboratories |
Medical devices containing rapamycin analogs
|
US7399480B2
(en)
|
1997-09-26 |
2008-07-15 |
Abbott Laboratories |
Methods of administering tetrazole-containing rapamycin analogs with other therapeutic substances using medical devices
|
US20030129215A1
(en)
|
1998-09-24 |
2003-07-10 |
T-Ram, Inc. |
Medical devices containing rapamycin analogs
|
US6015815A
(en)
*
|
1997-09-26 |
2000-01-18 |
Abbott Laboratories |
Tetrazole-containing rapamycin analogs with shortened half-lives
|
US8257726B2
(en)
|
1997-09-26 |
2012-09-04 |
Abbott Laboratories |
Compositions, systems, kits, and methods of administering rapamycin analogs with paclitaxel using medical devices
|
US8257725B2
(en)
|
1997-09-26 |
2012-09-04 |
Abbott Laboratories |
Delivery of highly lipophilic agents via medical devices
|
US8394398B2
(en)
|
1997-09-26 |
2013-03-12 |
Abbott Laboratories |
Methods of administering rapamycin analogs with anti-inflammatories using medical devices
|
US7357942B2
(en)
|
1997-09-26 |
2008-04-15 |
Abbott Laboratories |
Compositions, systems, and kits for administering zotarolimus and paclitaxel to blood vessel lumens
|
US8057816B2
(en)
|
1997-09-26 |
2011-11-15 |
Abbott Laboratories |
Compositions and methods of administering paclitaxel with other drugs using medical devices
|
JP2002503692A
(ja)
*
|
1998-02-23 |
2002-02-05 |
藤沢薬品工業株式会社 |
マクロライド系化合物の緑内障治療用途
|
AUPP223198A0
(en)
*
|
1998-03-06 |
1998-04-02 |
Fujisawa Pharmaceutical Co., Ltd. |
New use
|
EP1064942B9
(en)
|
1998-03-26 |
2011-03-02 |
Fujisawa Pharmaceutical Co., Ltd. |
Sustained release preparation of a macrolide
|
EE200100032A
(et)
|
1998-07-17 |
2002-06-17 |
Agouron Pharmaceuticals, Inc. |
Ühendid, kompositsioonid ja meetodid neuronaalse kasvu ja elongatsiooni stimuleerimiseks
|
US7455853B2
(en)
|
1998-09-24 |
2008-11-25 |
Abbott Cardiovascular Systems Inc. |
Medical devices containing rapamycin analogs
|
US7960405B2
(en)
|
1998-09-24 |
2011-06-14 |
Abbott Laboratories |
Compounds and methods for treatment and prevention of diseases
|
US8257724B2
(en)
|
1998-09-24 |
2012-09-04 |
Abbott Laboratories |
Delivery of highly lipophilic agents via medical devices
|
MXPA01003376A
(es)
|
1998-10-02 |
2002-11-07 |
Kosan Biosciences Inc |
Enzimas policetido sintetasa y construcciones de acido desoxirribonucleico recombinante para las mismas.
|
DE19853487A1
(de)
|
1998-11-19 |
2000-05-25 |
Fumapharm Ag Muri |
Verwendung von Dialkylfumaraten
|
GB9826656D0
(en)
|
1998-12-03 |
1999-01-27 |
Novartis Ag |
Organic compounds
|
US6121257A
(en)
*
|
1999-03-31 |
2000-09-19 |
Abbott Laboratories |
Sulfamate containing macrocyclic immunomodulators
|
MXPA01009935A
(es)
*
|
1999-03-31 |
2002-05-06 |
Abbott Lab |
Inmunomoduladores macorciclicos que contienen fosfato.
|
US7063857B1
(en)
|
1999-04-30 |
2006-06-20 |
Sucampo Ag |
Use of macrolide compounds for the treatment of dry eye
|
ES2214273T3
(es)
*
|
1999-04-30 |
2004-09-16 |
The Regents Of The University Of Michigan |
Utilizacion de benzodiazepinas para el tratamiento de enfermedades autoinmunes inducidas por apoptosis.
|
US20060025388A1
(en)
*
|
1999-04-30 |
2006-02-02 |
Glick Gary D |
Compositions and methods relating to novel compounds and targets thereof
|
US20040176358A1
(en)
*
|
1999-04-30 |
2004-09-09 |
The Regents Of The University Of Michigan |
Compositions and methods relating to novel compounds and targets thereof
|
US20050113460A1
(en)
*
|
1999-04-30 |
2005-05-26 |
The Regents Of The University Of Michigan |
Compositions and methods relating to novel compounds and targets thereof
|
US7144880B2
(en)
|
1999-04-30 |
2006-12-05 |
Regents Of The University Of Michigan |
Compositions relating to novel compounds and targets thereof
|
US20030119029A1
(en)
*
|
1999-04-30 |
2003-06-26 |
Regents Of The University Of Michigan |
Compositions and methods relating to novel benzodiazepine compounds and targets thereof
|
GB9917158D0
(en)
*
|
1999-07-21 |
1999-09-22 |
Fujisawa Pharmaceutical Co |
New use
|
US20030018044A1
(en)
*
|
2000-02-18 |
2003-01-23 |
Peyman Gholam A. |
Treatment of ocular disease
|
US6471980B2
(en)
|
2000-12-22 |
2002-10-29 |
Avantec Vascular Corporation |
Intravascular delivery of mycophenolic acid
|
US7018405B2
(en)
|
2000-12-22 |
2006-03-28 |
Avantec Vascular Corporation |
Intravascular delivery of methylprednisolone
|
AR033151A1
(es)
*
|
2001-04-12 |
2003-12-03 |
Sucampo Pharmaceuticals Inc |
Agente para el tratamiento oftalmico topico de las enfermedades inflamatorias oculares
|
US6656460B2
(en)
|
2001-11-01 |
2003-12-02 |
Yissum Research Development |
Method and composition for dry eye treatment
|
US7452692B2
(en)
*
|
2002-02-13 |
2008-11-18 |
Teva Gyógyszergyár Zártkörüen Müködö Részvénytársaság |
Method for extracting a macrolide from biomatter
|
WO2003068980A2
(en)
|
2002-02-13 |
2003-08-21 |
Biogal Gyogyszergyar Rt |
Method for extracting a macrolide from biomatter
|
AU2003213125B2
(en)
*
|
2002-02-22 |
2008-02-21 |
3M Innovative Properties Company |
Method of reducing and treating UVB-induced immunosuppression
|
AU2002321821A1
(en)
*
|
2002-06-28 |
2004-01-19 |
Biocon Limited |
Solid state fermentation and fed batch for the production of an immunosuppressant
|
EP2263709A1
(en)
|
2002-09-06 |
2010-12-22 |
Abbott Laboratories |
Medical device having hydration inhibitor
|
AU2003300076C1
(en)
|
2002-12-30 |
2010-03-04 |
Angiotech International Ag |
Drug delivery from rapid gelling polymer composition
|
WO2004069845A1
(en)
*
|
2003-02-10 |
2004-08-19 |
Biocon Limited |
Solid state fermentation and fed batch for the production of an immunosuppressant
|
DE04758730T1
(de)
|
2003-03-31 |
2005-06-23 |
Biogal Gyogyszergyar Rt. |
Kristallisierung und Reinigung von Makroliden
|
US20060169199A1
(en)
*
|
2003-03-31 |
2006-08-03 |
Vilmos Keri |
Crystallization and purification of macrolides
|
KR100486016B1
(ko)
*
|
2003-07-09 |
2005-04-29 |
주식회사종근당 |
타크로리무스의 속용성 고체분산체 및 이의 제조방법
|
JP2007521013A
(ja)
*
|
2003-07-24 |
2007-08-02 |
テバ ジョジセルジャール ザ−トケルエン ムケド レ−スベニュタ−ルシャシャ−グ |
マクロライドの精製方法
|
EP1652550A1
(en)
*
|
2003-08-05 |
2006-05-03 |
Kaneka Corporation |
Stent to be placed in vivo
|
ATE531368T1
(de)
|
2003-08-29 |
2011-11-15 |
Veloxis Pharmaceuticals As |
Tacrolimus enthaltende zusammensetzungen mit modifizierter freisetzung
|
AU2004267909B2
(en)
|
2003-08-29 |
2008-12-18 |
Veloxis Pharmaceuticals, Inc. |
Modified release compositions comprising tacrolimus
|
TW200517114A
(en)
|
2003-10-15 |
2005-06-01 |
Combinatorx Inc |
Methods and reagents for the treatment of immunoinflammatory disorders
|
DE602004018547D1
(de)
*
|
2003-10-17 |
2009-01-29 |
Ranbaxy Lab Ltd |
Herstellung von tacrolimus (fk-506) unter verwendung neuer streptomyces-spezies
|
NZ547389A
(en)
|
2003-11-21 |
2009-11-27 |
Combinatorx Inc |
Combinations of a compound such as ibudilast and a corticosteroid for the treatment of inflammatory disorders
|
SI1697383T1
(sl)
*
|
2003-12-05 |
2014-09-30 |
Biocon Limited |
Postopek za čiščenje takrolimusa
|
KR100485877B1
(ko)
*
|
2003-12-30 |
2005-04-28 |
종근당바이오 주식회사 |
타크롤리무스를 생산하는 미생물 및 이를 이용한타크롤리무스의 대량 생산방법
|
US20050176080A1
(en)
*
|
2004-02-10 |
2005-08-11 |
Vani Bodepudi |
Hapten, immunogens and derivatives of ascomycin useful for preparation of antibodies and immunoassays
|
EP1735042B1
(en)
|
2004-03-19 |
2011-11-23 |
Abbott Laboratories |
Multiple drug delivery from a balloon and a prosthesis
|
US8431145B2
(en)
|
2004-03-19 |
2013-04-30 |
Abbott Laboratories |
Multiple drug delivery from a balloon and a prosthesis
|
CA2562805C
(en)
*
|
2004-04-12 |
2014-03-11 |
Biocon Limited |
Process for the production of macrolides using a novel strain, streptomyces sp. bicc 7522
|
US20090275099A1
(en)
*
|
2004-04-27 |
2009-11-05 |
Regents Of The University Of Michigan |
Methods and compositions for treating diseases and conditions associated with mitochondrial function
|
US20050272723A1
(en)
*
|
2004-04-27 |
2005-12-08 |
The Regents Of The University Of Michigan |
Methods and compositions for treating diseases and conditions associated with mitochondrial function
|
JP2006014722A
(ja)
*
|
2004-06-02 |
2006-01-19 |
Keio Gijuku |
遺伝子マーカー及びその利用
|
WO2006115509A2
(en)
|
2004-06-24 |
2006-11-02 |
Novartis Vaccines And Diagnostics Inc. |
Small molecule immunopotentiators and assays for their detection
|
US7534448B2
(en)
*
|
2004-07-01 |
2009-05-19 |
Yale University |
Methods of treatment with drug loaded polymeric materials
|
US20060014677A1
(en)
*
|
2004-07-19 |
2006-01-19 |
Isotechnika International Inc. |
Method for maximizing efficacy and predicting and minimizing toxicity of calcineurin inhibitor compounds
|
US20060052369A1
(en)
*
|
2004-09-07 |
2006-03-09 |
The Regents Of The University Of Michigan |
Compositions and methods relating to novel compounds and targets thereof
|
CN101031654A
(zh)
*
|
2004-09-10 |
2007-09-05 |
伊瓦克斯制药有限公司 |
结晶他克莫司的分离方法
|
MX2007002808A
(es)
*
|
2004-09-10 |
2007-10-10 |
Ivax Pharmaceuticals Sro |
Proceso para el aislamiento de tacrolimus cristalino.
|
GT200500282A
(es)
*
|
2004-10-12 |
2006-05-04 |
|
Heteroatomos conteniendo compuestos triciclicos.
|
ITMI20042098A1
(it)
*
|
2004-11-03 |
2005-02-03 |
Antibioticos Spa |
Processo per la purificazione di tacrolimus
|
MX2007005222A
(es)
|
2004-12-01 |
2007-06-26 |
Teva Gyogyszergyar Zartkoruen |
Pimecrolimus amorfo no higroscopico y en polvo.
|
AU2005316473B2
(en)
*
|
2004-12-15 |
2011-07-14 |
Elan Pharma International Ltd. |
Nanoparticulate tacrolimus formulations
|
US20060149057A1
(en)
*
|
2004-12-22 |
2006-07-06 |
Vilmos Keri |
Method of purifying macrolides
|
EP1845996A4
(en)
*
|
2005-01-03 |
2009-04-29 |
Univ Michigan |
COMPOSITIONS AND METHODS RELATING TO NEW COMPOUNDS AND TARGETS
|
EP1833835A1
(en)
*
|
2005-01-05 |
2007-09-19 |
Teva Gyogyszergyar Zartkoruen Müködö R Szv Nytarsa |
Amorphous tacrolimus and preparation thereof
|
ATE532064T1
(de)
*
|
2005-01-13 |
2011-11-15 |
Univ Keio |
Genmarker und dessen verwendung
|
EP3138531A1
(en)
|
2005-03-23 |
2017-03-08 |
Abbott Laboratories |
Compositions and methods of administering rapamycin analogs using medical devices for long-term efficacy
|
EP1868663B1
(en)
|
2005-03-23 |
2011-11-16 |
Abbott Laboratories |
Delivery of highly lipophilic agents via medical devices
|
WO2007053193A2
(en)
|
2005-06-01 |
2007-05-10 |
The Regents Of The University Of Michigan |
Unsolvated benzodiazepine compositions and methods
|
CN1876822B
(zh)
*
|
2005-06-06 |
2010-05-12 |
上海市农药研究所 |
他克莫司的产生菌株及生产方法
|
WO2007013017A1
(en)
*
|
2005-07-29 |
2007-02-01 |
Ranbaxy Laboratories Limited |
A process for purification of macrolides
|
ITMI20051549A1
(it)
*
|
2005-08-05 |
2007-02-06 |
Antibioticos Spa |
Purificazione del tacrolimus su supporti dimorigine vegetale
|
WO2007029082A2
(en)
*
|
2005-09-05 |
2007-03-15 |
Ranbaxy Laboratories Limited |
An improved fermentation process for preparing ascomycin
|
US20080318289A1
(en)
*
|
2005-10-05 |
2008-12-25 |
Parveen Kumar |
Fermentation Processes for the Preparation of Tacrolimus
|
US20070105844A1
(en)
*
|
2005-10-26 |
2007-05-10 |
Regents Of The University Of Michigan |
Therapeutic compositions and methods
|
US8088759B2
(en)
|
2005-11-01 |
2012-01-03 |
The Regents Of The University Of Michigan |
1,4-benzodiazepine-2,5-diones with therapeutic properties
|
ZA200804550B
(en)
|
2005-11-09 |
2009-08-26 |
Combinatorx Inc |
Methods, compositions, and kits for the treatment of medical conditions
|
US7622477B2
(en)
|
2006-02-28 |
2009-11-24 |
Cordis Corporation |
Isomers and 42-epimers of rapamycin alkyl ether analogs, methods of making and using the same
|
US7678901B2
(en)
|
2006-02-28 |
2010-03-16 |
Wyeth |
Rapamycin analogs containing an antioxidant moiety
|
US20080000834A1
(en)
*
|
2006-03-15 |
2008-01-03 |
Ladislav Cvak |
Process for purifying Tacrolimus
|
US8022188B2
(en)
*
|
2006-04-24 |
2011-09-20 |
Abbott Laboratories |
Immunosuppressant binding antibodies and methods of obtaining and using same
|
US7759338B2
(en)
*
|
2006-04-27 |
2010-07-20 |
The Regents Of The University Of Michigan |
Soluble 1,4 benzodiazepine compounds and stable salts thereof
|
CA2659549C
(en)
|
2006-06-09 |
2013-07-30 |
The Regents Of The University Of Michigan |
Compositions and methods relating to novel compounds and targets thereof
|
CA2660804A1
(en)
|
2006-08-31 |
2008-03-06 |
Astellas Pharma Inc. |
Reverse targeting lipid vesicle
|
US20080161324A1
(en)
*
|
2006-09-14 |
2008-07-03 |
Johansen Lisa M |
Compositions and methods for treatment of viral diseases
|
TW200837067A
(en)
*
|
2006-11-06 |
2008-09-16 |
Teva Gyogyszergyar Zartkoruen Mukodo Reszvenytarsasag |
Ascomycin and pimecrolimus having reduced levels of desmethylascomycin and 32-deoxy-32-epichloro-desmethylascomycin respectively, and methods for preparation thereof
|
US9044391B2
(en)
*
|
2007-01-10 |
2015-06-02 |
Board Of Regents, The University Of Texas System |
Enhanced delivery of immunosuppressive drug compositions for pulmonary delivery
|
US10265407B2
(en)
|
2007-02-15 |
2019-04-23 |
Yale University |
Modular nanodevices for smart adaptable vaccines
|
WO2008109347A2
(en)
*
|
2007-03-02 |
2008-09-12 |
Yale University |
Methods for ex vivo administration of drugs to grafts using polymeric nanoparticles
|
BRPI0808653A2
(pt)
*
|
2007-03-09 |
2014-08-19 |
Univ Michigan |
Composições e métodos referindo-se a novos compostos e alvos dos mesmos.
|
US12083103B2
(en)
|
2007-05-30 |
2024-09-10 |
Veloxis Pharmaceuticals, Inc. |
Tacrolimus for improved treatment of transplant patients
|
EP2167033B1
(en)
|
2007-05-30 |
2017-04-19 |
Veloxis Pharmaceuticals A/S |
Once daily oral dosage form comprising tacrolimus
|
KR100891313B1
(ko)
|
2007-08-17 |
2009-03-31 |
(주) 제노텍 |
담체로 작용하는 흡착성 수지의 제공에 의한 트리사이클로화합물의 생산 및 추출 방법
|
WO2009036175A2
(en)
|
2007-09-14 |
2009-03-19 |
The Regents Of The University Of Michigan |
F1f0-atpase inhibitors and related methods
|
US8188072B2
(en)
|
2007-11-06 |
2012-05-29 |
The Regents Of The University Of Michigan |
Benzodiazepinone compounds useful in the treatment of skin conditions
|
WO2009089549A1
(en)
*
|
2008-01-11 |
2009-07-16 |
Massachusetts Eye & Ear Infirmary |
Conditional-stop dimerizable caspase transgenic animals
|
KR101003042B1
(ko)
|
2008-03-17 |
2010-12-21 |
종근당바이오 주식회사 |
고순도 타크로리무스의 정제 방법
|
AU2009233906A1
(en)
*
|
2008-04-08 |
2009-10-15 |
Amyris, Inc. |
Expression of heterologous sequences
|
US8173621B2
(en)
|
2008-06-11 |
2012-05-08 |
Gilead Pharmasset Llc |
Nucleoside cyclicphosphates
|
WO2010021681A2
(en)
*
|
2008-08-18 |
2010-02-25 |
Combinatorx (Singapore) Pte. Ltd. |
Compositions and methods for treatment of viral diseases
|
WO2010030891A2
(en)
|
2008-09-11 |
2010-03-18 |
The Regents Of The University Of Michigan |
Aryl guanidine f1f0-atpase inhibitors and related methods
|
KR100910165B1
(ko)
|
2008-09-18 |
2009-07-30 |
(주) 제노텍 |
은 이온 용액 추출을 이용한 불포화 알킬기를 가진 락톤 화합물 정제방법
|
CA2738831C
(en)
*
|
2008-10-08 |
2016-05-24 |
Takata Seiyaku Co., Ltd. |
Tacrolimus preparation for external applications
|
AR074977A1
(es)
|
2008-12-23 |
2011-03-02 |
Pharmasset Inc |
Sintesis de nucleosidos de purina
|
CN102753563A
(zh)
|
2008-12-23 |
2012-10-24 |
吉利德制药有限责任公司 |
核苷类似物
|
SG172359A1
(en)
|
2008-12-23 |
2011-07-28 |
Pharmasset Inc |
Nucleoside phosphoramidates
|
US8604023B2
(en)
|
2009-04-17 |
2013-12-10 |
The Regents Of The University Of Michigan |
1,4-benzodiazepinone compounds and their use in treating cancer
|
CN101712686B
(zh)
*
|
2009-06-22 |
2012-08-29 |
鲁南制药集团股份有限公司 |
一种发酵液中他克莫司的分离纯化方法
|
EP2272963A1
(en)
*
|
2009-07-09 |
2011-01-12 |
LEK Pharmaceuticals d.d. |
Process for Preparation of Tacrolimus
|
WO2011035124A1
(en)
|
2009-09-18 |
2011-03-24 |
The Regents Of The University Of Michigan |
Benzodiazepinone compounds and methods of treatment using same
|
CN102753179A
(zh)
|
2009-11-17 |
2012-10-24 |
密执安大学评议会 |
具有治疗性能的1,4-苯并二氮杂*-2,5-二酮和相关化合物
|
CN102753544A
(zh)
|
2009-11-17 |
2012-10-24 |
密执安大学评议会 |
具有治疗性能的1,4-苯并二氮杂*-2,5-二酮和相关化合物
|
US20110130711A1
(en)
*
|
2009-11-19 |
2011-06-02 |
Follica, Inc. |
Hair growth treatment
|
US8480620B2
(en)
|
2009-12-11 |
2013-07-09 |
Abbott Cardiovascular Systems Inc. |
Coatings with tunable solubility profile for drug-coated balloon
|
US8951595B2
(en)
|
2009-12-11 |
2015-02-10 |
Abbott Cardiovascular Systems Inc. |
Coatings with tunable molecular architecture for drug-coated balloon
|
DK2575769T3
(en)
|
2010-02-17 |
2016-09-26 |
Veloxis Pharmaceuticals As |
stabilized tacrolismussammensætning
|
DK2552930T3
(en)
|
2010-03-31 |
2015-12-07 |
Gilead Pharmasset Llc |
Crystalline (S) -isopropyl 2 - (((S) - (((2R, 3R, 4R, 5R) -5- (2,4-dioxo-3,4-DIHYDROPYRIMIDIN- 1- (2 H) -yl) - 4-fluoro-3-hydroxy-4-methyltetrahydrofuran-2-yl) methoxy) (phenoxy) phosphoryl) amino) propanoate
|
WO2011163600A2
(en)
|
2010-06-25 |
2011-12-29 |
Apt Pharmaceuticals, Inc. |
Tacrolimus compositions for aerosol administration
|
KR101261131B1
(ko)
|
2010-08-24 |
2013-05-06 |
이화여자대학교 산학협력단 |
신규 타크롤리무스 유도체, 상기 유도체를 포함하는 신경 보호용 조성물, 상기 유도체를 포함하는 면역 억제용 조성물, 상기 유도체의 생산 방법 및 상기 유도체의 생산 균주
|
MA34586B1
(fr)
|
2010-08-25 |
2013-10-02 |
Medis Lab |
Particules cristallines de tacrolimus micronise a surface modifiee et compositions pharmaceutiques associees
|
US10117411B2
(en)
|
2010-10-06 |
2018-11-06 |
Dow Agrosciences Llc |
Maize cytoplasmic male sterility (CMS) C-type restorer RF4 gene, molecular markers and their use
|
PL3556774T3
(pl)
|
2011-03-11 |
2024-07-01 |
Beth Israel Deaconess Medical Center Inc. |
Przeciwciała anty-cd40 i ich zastosowania
|
EP2841098A4
(en)
|
2012-04-23 |
2016-03-02 |
Allertein Therapeutics Llc |
NANOPARTICLES FOR THE TREATMENT OF ALLERGIES
|
RS57497B1
(sr)
|
2013-03-14 |
2018-10-31 |
Alkermes Pharma Ireland Ltd |
Prolekovi fumarata i njihova upotreba u lečenju raznih bolesti
|
US8669281B1
(en)
|
2013-03-14 |
2014-03-11 |
Alkermes Pharma Ireland Limited |
Prodrugs of fumarates and their use in treating various diseases
|
EP3760223A1
(en)
|
2013-04-03 |
2021-01-06 |
N-Fold Llc |
Nanoparticle composition for desensitizing a subject to peanut allergens
|
US9814703B2
(en)
|
2013-11-14 |
2017-11-14 |
The Board Of Trustees Of The Leland Stanford Junior University |
Methods for treating cancer by activation of BMP signaling
|
CN104650112B
(zh)
*
|
2013-11-18 |
2018-07-31 |
山东新时代药业有限公司 |
他克莫司8-丙基类似物的制备方法
|
UY35927A
(es)
|
2013-12-31 |
2015-07-31 |
Dow Agrosciences Llc |
?gen restaurador rf3 de tipo s de la esterilidad masculina citoplasmática del maíz (cms), marcadores moleculares y sus usos?.
|
EP3094324A4
(en)
*
|
2014-01-13 |
2017-02-22 |
Amplyx Pharmaceuticals, Inc. |
Antifungal compounds
|
CA2935167C
(en)
|
2014-01-16 |
2022-02-22 |
Musc Foundation For Research Development |
Targeted nanocarriers for the administration of immunosuppressive agents
|
JP6337135B2
(ja)
|
2014-02-24 |
2018-06-06 |
アルカーメス ファーマ アイルランド リミテッド |
フマル酸エステルのスルホンアミドプロドラッグ及びスルフィンアミドプロドラッグ並びに種々の疾患の治療におけるその使用
|
KR101694879B1
(ko)
*
|
2014-08-01 |
2017-01-12 |
주식회사 인트론바이오테크놀로지 |
면역억제활성 없이 신경재생활성이 유지되는 fk506 유도체 및 그의 용도
|
JPWO2016068208A1
(ja)
|
2014-10-28 |
2017-08-10 |
晃史 山口 |
妊娠状態を改善するための薬剤及びその利用
|
EP4066822A1
(en)
|
2015-08-19 |
2022-10-05 |
Vivus, Inc. |
Pharmaceutical formulations
|
CA3002789A1
(en)
|
2015-09-04 |
2017-03-09 |
Primatope Therapeutics Inc. |
Humanized anti-cd40 antibodies and uses thereof
|
CN106074367A
(zh)
*
|
2016-07-20 |
2016-11-09 |
中山大学中山眼科中心 |
含fk506类化合物/fkbp蛋白二聚体的药物组合物及其制备方法
|
CN108384819B
(zh)
*
|
2017-02-03 |
2021-06-25 |
上海医药工业研究院 |
一种用于发酵他克莫司的培养基以及发酵方法
|
RU2686779C1
(ru)
*
|
2018-07-26 |
2019-04-30 |
Общество с ограниченной ответственностью "Изварино Фарма" |
Штамм streptomyces tsukubensis - продуцент такролимуса и способ получения такролимуса
|
US20210228551A1
(en)
|
2018-08-10 |
2021-07-29 |
Koushi Yamaguchi |
Therapeutic agent for humoral immunity-related diseases in maternofetal relationship
|
WO2020076738A2
(en)
*
|
2018-10-12 |
2020-04-16 |
Bellicum Pharmaceuticals, Inc |
Protein-binding compounds
|
WO2020117134A1
(en)
|
2018-12-04 |
2020-06-11 |
İlko İlaç Sanayi̇ Ve Ti̇caret A.Ş. |
Stable tacrolimus ointment formulation for topical treatment of skin conditions
|
EP3900729A4
(en)
|
2018-12-18 |
2022-09-07 |
Koushi Yamaguchi |
AGENT FOR TREATING INFERTILITY, RECURRENT MISSORAGE AND IMPROVING PREGNANCY
|
KR102135527B1
(ko)
*
|
2018-12-18 |
2020-07-20 |
이문수 |
발가락 습기 제거 양말
|
GR1009790B
(el)
|
2019-03-20 |
2020-08-03 |
Φαρματεν Α.Β.Ε.Ε. |
Σκευασμα παρατεταμενης αποδεσμευσης που περιλαμβανει τακρολιμους
|
IL305524A
(en)
|
2021-03-03 |
2023-10-01 |
Sana Biotechnology Inc |
Immunosuppressive treatments for use with cardiomyocyte cell treatments, and associated methods and preparations
|