CY1119590T1 - Ρυθμιστες dll3 και μεθοδοι χρησης - Google Patents
Ρυθμιστες dll3 και μεθοδοι χρησηςInfo
- Publication number
- CY1119590T1 CY1119590T1 CY20171101098T CY171101098T CY1119590T1 CY 1119590 T1 CY1119590 T1 CY 1119590T1 CY 20171101098 T CY20171101098 T CY 20171101098T CY 171101098 T CY171101098 T CY 171101098T CY 1119590 T1 CY1119590 T1 CY 1119590T1
- Authority
- CY
- Cyprus
- Prior art keywords
- methods
- dll3
- regulators
- modulators
- derivatives
- Prior art date
Links
- 102100036466 Delta-like protein 3 Human genes 0.000 title 1
- 101000928513 Homo sapiens Delta-like protein 3 Proteins 0.000 title 1
- 229940127276 delta-like ligand 3 Drugs 0.000 title 1
- 230000002062 proliferating effect Effects 0.000 abstract 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
- A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
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- A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
- A61K31/5513—1,4-Benzodiazepines, e.g. diazepam or clozapine
- A61K31/5517—1,4-Benzodiazepines, e.g. diazepam or clozapine condensed with five-membered rings having nitrogen as a ring hetero atom, e.g. imidazobenzodiazepines, triazolam
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- A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
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Abstract
Παρέχονται νέοι ρυθμιστές, που περιλαμβάνουν αντισώματα και παράγωγα αυτών, και μέθοδοι χρήσης τέτοιων ρυθμιστών για θεραπεία πολλαπλασιαστικών διαταραχών.
Applications Claiming Priority (3)
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US201261603173P | 2012-02-24 | 2012-02-24 | |
US201261719803P | 2012-10-29 | 2012-10-29 | |
PCT/US2013/027391 WO2013126746A2 (en) | 2012-02-24 | 2013-02-22 | Novel modulators and methods of use |
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CY1119590T1 true CY1119590T1 (el) | 2018-03-07 |
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CY20171101098T CY1119590T1 (el) | 2012-02-24 | 2017-10-20 | Ρυθμιστες dll3 και μεθοδοι χρησης |
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BR (1) | BR112014020826A8 (el) |
CA (2) | CA3050672A1 (el) |
CL (2) | CL2014002240A1 (el) |
CO (1) | CO7111274A2 (el) |
CY (1) | CY1119590T1 (el) |
DK (1) | DK2817338T3 (el) |
ES (2) | ES2812849T3 (el) |
HK (4) | HK1200174A1 (el) |
HR (1) | HRP20171549T1 (el) |
HU (1) | HUE037021T2 (el) |
IL (2) | IL234155B (el) |
LT (1) | LT2817338T (el) |
ME (1) | ME02928B (el) |
MX (2) | MX2014010074A (el) |
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PE (2) | PE20190658A1 (el) |
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SG (2) | SG11201405131XA (el) |
SI (1) | SI2817338T1 (el) |
WO (1) | WO2013126746A2 (el) |
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