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CY1113530T1 - Εμβολιο εναντι του αναπαραγωγικου και αναπνευστικου συνδρομου των χοιρων, βασισμενο στο απομονωθεν στελεχος ja-142 - Google Patents

Εμβολιο εναντι του αναπαραγωγικου και αναπνευστικου συνδρομου των χοιρων, βασισμενο στο απομονωθεν στελεχος ja-142

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Publication number
CY1113530T1
CY1113530T1 CY20121100590T CY121100590T CY1113530T1 CY 1113530 T1 CY1113530 T1 CY 1113530T1 CY 20121100590 T CY20121100590 T CY 20121100590T CY 121100590 T CY121100590 T CY 121100590T CY 1113530 T1 CY1113530 T1 CY 1113530T1
Authority
CY
Cyprus
Prior art keywords
prrs
virus
forms
respiratory syndrome
pigs
Prior art date
Application number
CY20121100590T
Other languages
English (en)
Inventor
William L Mengeling
Ann Vorwald
Kelly Lager
Mike Roof
Kelly Burkhart
David E Gorcyca
Original Assignee
The United States Of America, As Represented By The Secretary Of Agriculture
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by The United States Of America, As Represented By The Secretary Of Agriculture filed Critical The United States Of America, As Represented By The Secretary Of Agriculture
Publication of CY1113530T1 publication Critical patent/CY1113530T1/el

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    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
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    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • C12N7/04—Inactivation or attenuation; Producing viral sub-units
    • C12N7/08—Inactivation or attenuation by serial passage of virus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A—HUMAN NECESSITIES
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    • A—HUMAN NECESSITIES
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525—Virus
    • A61K2039/5254—Virus avirulent or attenuated
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K2039/55—Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
    • A61K2039/552—Veterinary vaccine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • C12N2770/00011—Details
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    • C12N2770/10061—Methods of inactivation or attenuation
    • C12N2770/10064—Methods of inactivation or attenuation by serial passage
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    • Y10S424/00—Drug, bio-affecting and body treating compositions
    • Y10S424/815—Viral vaccine for porcine species, e.g. swine

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  • Health & Medical Sciences (AREA)
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  • Chemical & Material Sciences (AREA)
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  • Bioinformatics & Cheminformatics (AREA)
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  • Animal Behavior & Ethology (AREA)
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  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pulmonology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

Παρέχονται ουσιαστικά μη παθογόνες μορφές άτυπου ιού του αναπαραγωγικού και αναπνευστικού συνδρόμου των χοίρων (ΡRRS) και αντίστοιχα εμβόλια που προκύπτουν από ανακαλλιέργεια κυτταρικών καλλιεργειών λοιμογόνων μορφών του ΡRRS. Ο μη παθογόνος άτυπος ιός ΡRRS που προκύπτει είναι χρήσιμος ως εμβόλιο στο ότι προκαλείται ειδική ανταπόκριση αντισώματος έναντι του ΡRRS δια του ενοφθαλμισμού των ζώων ξενιστών, αποδίδοντας τοιουτοτρόπως αποτελεσματική ανοσία έναντι τόσο προγενέστερα γνωστών στελεχών του ιού ΡRRS όσο και προσφάτως απομονωθέντων άτυπων στελεχών του ιού ΡRRS. Η προτιμώμενη τεχνική ανακαλλιέργειας εξασφαλίζει ότι ο ιός παραμένει σε λογαριθμική φάση αναπτύξεως ουσιαστικά σε όλη τη διάρκεια της διεργασίας, που ελαχιστοποιεί το χρόνο τον απαιτούμενο για την επίτευξη της εξασθενήσεως.
CY20121100590T 1999-04-22 2012-06-29 Εμβολιο εναντι του αναπαραγωγικου και αναπνευστικου συνδρομου των χοιρων, βασισμενο στο απομονωθεν στελεχος ja-142 CY1113530T1 (el)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US29811099A 1999-04-22 1999-04-22
US46187999A 1999-12-15 1999-12-15
EP10169336A EP2251419B1 (en) 1999-04-22 2000-04-21 Porcine reproductive and respiratory syndrome vaccine, based on isolate JA-142

Publications (1)

Publication Number Publication Date
CY1113530T1 true CY1113530T1 (el) 2016-06-22

Family

ID=26970484

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CY20121100590T CY1113530T1 (el) 1999-04-22 2012-06-29 Εμβολιο εναντι του αναπαραγωγικου και αναπνευστικου συνδρομου των χοιρων, βασισμενο στο απομονωθεν στελεχος ja-142

Country Status (14)

Country Link
US (5) US6641819B2 (el)
EP (2) EP2251419B1 (el)
JP (2) JP4778620B2 (el)
KR (1) KR100900370B1 (el)
AT (1) ATE474041T1 (el)
AU (1) AU4482200A (el)
CA (2) CA2370372C (el)
CY (1) CY1113530T1 (el)
DE (1) DE60044672D1 (el)
DK (2) DK1183332T3 (el)
ES (2) ES2388909T3 (el)
MX (1) MXPA01010681A (el)
PT (1) PT2251419E (el)
WO (1) WO2000065032A1 (el)

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