CY1112412T1 - Διεργασια για την παρασκευη του αλατος ασβεστιου της ροσουβαστατινης - Google Patents
Διεργασια για την παρασκευη του αλατος ασβεστιου της ροσουβαστατινηςInfo
- Publication number
- CY1112412T1 CY1112412T1 CY20111100442T CY111100442T CY1112412T1 CY 1112412 T1 CY1112412 T1 CY 1112412T1 CY 20111100442 T CY20111100442 T CY 20111100442T CY 111100442 T CY111100442 T CY 111100442T CY 1112412 T1 CY1112412 T1 CY 1112412T1
- Authority
- CY
- Cyprus
- Prior art keywords
- preparation
- calcium salt
- rosuvastatin calcium
- useful
- dihydroxyept
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/32—One oxygen, sulfur or nitrogen atom
- C07D239/42—One nitrogen atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Urology & Nephrology (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Cardiology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Περιγράφεται μία βελτιωμένη διεργασία για την παρασκευή άλατος ασβεστίου (Ε)-7-[4-(4-φθοροφαινυλ)-6-ισοπροπυλ-2-[μεθυλ(μεθυλσουλφονυλ)αμινο]πυριμιδιν-5-υλ](3R,5S)-3,5-διυδροξυεπτ-6-ενοϊκού οξέος, το οποίο είναι χρήσιμο για την παραγωγή ενός φαρμακευτικού προϊόντος χρήσιμου στη θεραπεία, μεταξύ άλλων, της υπερχοληστερολαιμίας, της υπερλιποπρωτεϊναιμίας και της αθηροσκλήρωσης.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB0218781.3A GB0218781D0 (en) | 2002-08-13 | 2002-08-13 | Chemical process |
EP03784274A EP1539711B1 (en) | 2002-08-13 | 2003-08-07 | Process for preparing the calcium salt of rosuvastatin |
Publications (1)
Publication Number | Publication Date |
---|---|
CY1112412T1 true CY1112412T1 (el) | 2015-12-09 |
Family
ID=9942204
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CY20111100442T CY1112412T1 (el) | 2002-08-13 | 2011-05-09 | Διεργασια για την παρασκευη του αλατος ασβεστιου της ροσουβαστατινης |
Country Status (30)
Country | Link |
---|---|
US (2) | US7511140B2 (el) |
EP (1) | EP1539711B1 (el) |
JP (1) | JP4588446B2 (el) |
KR (1) | KR101325827B1 (el) |
CN (1) | CN100361979C (el) |
AR (1) | AR040868A1 (el) |
AT (1) | ATE501125T1 (el) |
AU (1) | AU2003251369B2 (el) |
BR (1) | BR0313394A (el) |
CA (1) | CA2495296C (el) |
CY (1) | CY1112412T1 (el) |
DE (1) | DE60336326D1 (el) |
DK (1) | DK1539711T3 (el) |
ES (1) | ES2361009T3 (el) |
GB (1) | GB0218781D0 (el) |
HK (1) | HK1082735A1 (el) |
IL (1) | IL166626A (el) |
IS (1) | IS7728A (el) |
MX (1) | MXPA05001582A (el) |
MY (1) | MY135301A (el) |
NO (1) | NO329439B1 (el) |
NZ (1) | NZ538070A (el) |
PL (1) | PL375296A1 (el) |
PT (1) | PT1539711E (el) |
RU (1) | RU2326871C2 (el) |
SI (1) | SI1539711T1 (el) |
TW (1) | TWI316058B (el) |
UA (1) | UA83805C2 (el) |
WO (1) | WO2004014872A1 (el) |
ZA (1) | ZA200500745B (el) |
Families Citing this family (56)
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GB0312896D0 (en) | 2003-06-05 | 2003-07-09 | Astrazeneca Ab | Chemical process |
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GB0324791D0 (en) * | 2003-10-24 | 2003-11-26 | Astrazeneca Ab | Chemical process |
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CA2594692A1 (en) * | 2005-01-31 | 2006-08-03 | Ciba Specialty Chemicals Holding Inc. | Crystalline forms of rosuvastatin calcium salt |
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WO2011132172A1 (en) | 2010-04-23 | 2011-10-27 | Ranbaxy Laboratories Limited | NOVEL INTERMEDIATES FOR THE PREPARATION OF HMG-CoA REDUCTASE INHIBITORS |
HU230987B1 (hu) | 2010-11-29 | 2019-08-28 | Egis Gyógyszergyár Nyrt. | Eljárás nagy tisztaságú gyógyszeripari intermedierek előállítására |
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