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CY1110322T1 - Αναστολεις της her3 δραστικοτητας - Google Patents

Αναστολεις της her3 δραστικοτητας

Info

Publication number
CY1110322T1
CY1110322T1 CY20091100593T CY091100593T CY1110322T1 CY 1110322 T1 CY1110322 T1 CY 1110322T1 CY 20091100593 T CY20091100593 T CY 20091100593T CY 091100593 T CY091100593 T CY 091100593T CY 1110322 T1 CY1110322 T1 CY 1110322T1
Authority
CY
Cyprus
Prior art keywords
inhibitions
her3 activity
her3
activity
composition
Prior art date
Application number
CY20091100593T
Other languages
English (en)
Inventor
Axel Ullrich
Der Horst Edward Htun-Van
Original Assignee
MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=8178284&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CY1110322(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. filed Critical MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V.
Publication of CY1110322T1 publication Critical patent/CY1110322T1/el

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/32Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against translation products of oncogenes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/57Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
    • A61K2039/572Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2 cytotoxic response
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/39558Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against tumor tissues, cells, antigens
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2863Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for growth factors, growth regulators
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/531Production of immunochemical test materials
    • G01N33/532Production of labelled immunochemicals

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Oncology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

Η παρούσα εφεύρεση σχετίζεται με μια φαρμακευτική σύνθεση η οποία περιλαμβάνει ως έναν δραστικό παράγοντα έναν αναστολέα της HER3 δραστικότητας, συγκεκριμένα ένα αντι-HER3-αντίσωμα. Περαιτέρω, η χρήση αυτής της σύνθεσης για τη διάγνωση, πρόγνωση ή αντιμετώπιση νόσων υπερβολικού πολλαπλασιασμού, συγκεκριμένα νόσων όγκου γνωστοποιείται.
CY20091100593T 2001-08-09 2009-06-03 Αναστολεις της her3 δραστικοτητας CY1110322T1 (el)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP01119260A EP1283053A1 (en) 2001-08-09 2001-08-09 Inhibitors of HER3 activity
EP02794590A EP1414494B1 (en) 2001-08-09 2002-08-09 Inhibitory antibodies of her3 activity

Publications (1)

Publication Number Publication Date
CY1110322T1 true CY1110322T1 (el) 2015-01-14

Family

ID=8178284

Family Applications (1)

Application Number Title Priority Date Filing Date
CY20091100593T CY1110322T1 (el) 2001-08-09 2009-06-03 Αναστολεις της her3 δραστικοτητας

Country Status (13)

Country Link
US (1) US9011851B2 (el)
EP (3) EP1283053A1 (el)
JP (1) JP5226926B2 (el)
CN (2) CN102078613A (el)
AT (1) ATE424219T1 (el)
AU (1) AU2002333384B2 (el)
CA (1) CA2456723C (el)
CY (1) CY1110322T1 (el)
DE (1) DE60231407D1 (el)
DK (1) DK1414494T3 (el)
ES (1) ES2323772T3 (el)
PT (1) PT1414494E (el)
WO (1) WO2003013602A1 (el)

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Also Published As

Publication number Publication date
DK1414494T3 (da) 2009-07-06
JP5226926B2 (ja) 2013-07-03
EP1283053A1 (en) 2003-02-12
EP1414494A1 (en) 2004-05-06
EP2067792A2 (en) 2009-06-10
CN102078613A (zh) 2011-06-01
PT1414494E (pt) 2009-06-12
EP1414494B1 (en) 2009-03-04
DE60231407D1 (de) 2009-04-16
CA2456723C (en) 2016-02-09
US20040197332A1 (en) 2004-10-07
AU2002333384B2 (en) 2007-11-15
CN1541109A (zh) 2004-10-27
JP2005504044A (ja) 2005-02-10
ATE424219T1 (de) 2009-03-15
WO2003013602A1 (en) 2003-02-20
CA2456723A1 (en) 2003-02-20
CN1541109B (zh) 2013-07-10
ES2323772T3 (es) 2009-07-24
US9011851B2 (en) 2015-04-21

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