CO4890847A1 - Compuestos de piridiloxi - Google Patents
Compuestos de piridiloxiInfo
- Publication number
- CO4890847A1 CO4890847A1 CO97034431A CO97034431A CO4890847A1 CO 4890847 A1 CO4890847 A1 CO 4890847A1 CO 97034431 A CO97034431 A CO 97034431A CO 97034431 A CO97034431 A CO 97034431A CO 4890847 A1 CO4890847 A1 CO 4890847A1
- Authority
- CO
- Colombia
- Prior art keywords
- compound
- formula
- hydrogen
- piridiloxi
- compounds
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pain & Pain Management (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
Un compuesto de fórmula (I) o una de sus sales: en la que: X es CH ó N; R1 es hidrógeno o alquilo C1-6 ; los grupos R2 y R3 son independientemente halógeno, alquilo C1-6 o trifluorometilo. Un procedimiento para la preparación de un compuesto de una cualquiera de las reivindicaciones 1 a 6, que comprende hacer reaccionar de un compuesto de fórmula (II): con un compuesto de fórmula (III): en las que R1 , R2 y R3 son como se definen en la fórmula (I) y A y B tienen los siguientes significados: (i) A es -N=C=O y B es hidrógeno, (ii) A es -NHCOL y B es hidrógeno, (iii) A es -NH2 y B es COL, o (iv) A es halógeno y B es -CONH2 en las que L es un grupo lábil, incluyendo un halógeno, imidazol o fenoxi o feniltio opcionalmente sustituidos.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9612883.0A GB9612883D0 (en) | 1996-06-20 | 1996-06-20 | Novel compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CO4890847A1 true CO4890847A1 (es) | 2000-02-28 |
Family
ID=10795575
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CO97034431A CO4890847A1 (es) | 1996-06-20 | 1997-06-20 | Compuestos de piridiloxi |
Country Status (33)
| Country | Link |
|---|---|
| US (1) | US6369060B1 (es) |
| EP (1) | EP0912554B1 (es) |
| JP (1) | JP2000512306A (es) |
| KR (1) | KR20000022045A (es) |
| CN (1) | CN1229408A (es) |
| AP (2) | AP9801410A0 (es) |
| AR (1) | AR008243A1 (es) |
| AT (1) | ATE228514T1 (es) |
| AU (1) | AU718597B2 (es) |
| BG (1) | BG103089A (es) |
| BR (1) | BR9709911A (es) |
| CA (1) | CA2258240A1 (es) |
| CO (1) | CO4890847A1 (es) |
| CZ (1) | CZ420598A3 (es) |
| DE (1) | DE69717449T2 (es) |
| DZ (1) | DZ2250A1 (es) |
| EA (1) | EA001780B1 (es) |
| ES (1) | ES2187783T3 (es) |
| GB (1) | GB9612883D0 (es) |
| HU (1) | HUP9903439A3 (es) |
| ID (1) | ID19433A (es) |
| IL (1) | IL127417A0 (es) |
| MA (1) | MA24214A1 (es) |
| NO (1) | NO985972D0 (es) |
| NZ (1) | NZ333229A (es) |
| OA (1) | OA10944A (es) |
| PE (1) | PE86698A1 (es) |
| PL (1) | PL330796A1 (es) |
| SK (1) | SK282706B6 (es) |
| TR (1) | TR199802661T2 (es) |
| TW (1) | TW382015B (es) |
| WO (1) | WO1997048699A1 (es) |
| ZA (1) | ZA975415B (es) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1999043650A2 (en) * | 1998-02-25 | 1999-09-02 | Smithkline Beecham Plc | Process(es) for the preparation of 6-trifluoromethyl-indoline derivatives |
| GB0019950D0 (en) * | 2000-08-12 | 2000-09-27 | Smithkline Beecham Plc | Compounds |
| EP1451176A2 (en) | 2001-11-28 | 2004-09-01 | PHARMACIA & UPJOHN COMPANY | Benzazepine derivatives and their use as 5-ht ligands |
| CA2475254A1 (en) * | 2002-03-04 | 2003-09-18 | Pharmacia & Upjohn Company | Pyridinyloxy derivatives as 5-ht receptor ligands |
| KR101062376B1 (ko) * | 2008-04-10 | 2011-09-06 | 한국화학연구원 | 신규 인돌 카르복실산 비스피리딜 카르복사마이드 유도체,이의 제조방법 및 이를 유효성분으로 함유하는 조성물 |
| JP2012515202A (ja) | 2009-01-16 | 2012-07-05 | マサチューセッツ インスティテュート オブ テクノロジー | 自閉症圏障害の診断および処置 |
| EP2651403B1 (en) | 2010-12-17 | 2020-12-02 | Glaxo Group Limited | Use of lp-pla2 inhibitors in the treatment and prevention of eye diseases |
| WO2014046544A1 (en) | 2012-09-21 | 2014-03-27 | Aapa B.V. | Substituted 3-heteroaryloxy-3-(hetero)aryl-propylamines as serotonin transporter and serotonin ht2c receptor modulators |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1989001333A1 (en) * | 1987-08-07 | 1989-02-23 | The Australian National University | IMIDAZO[1,2-b]PYRIDAZINES |
| NZ254785A (en) * | 1992-08-20 | 1995-09-26 | Smithkline Beecham Plc | Heterocyclically-condensed indoles and medicaments |
| GB9313913D0 (en) * | 1993-07-06 | 1993-08-18 | Smithkline Beecham Plc | Novel compounds |
| RO115522B1 (ro) * | 1995-02-02 | 2000-03-30 | Smithkline Beecham P.L.C. | Derivaţi de indolină, procedee pentru prepararea acestora, compoziţii farmaceutice care îi conţin şi metodă de tratament |
| GB9607219D0 (en) * | 1996-04-04 | 1996-06-12 | Smithkline Beecham Plc | Novel compounds |
| GB9615767D0 (en) * | 1996-07-26 | 1996-09-04 | Smithkline Beecham Plc | Novel treatment |
-
1996
- 1996-06-20 GB GBGB9612883.0A patent/GB9612883D0/en active Pending
-
1997
- 1997-06-16 ES ES97928224T patent/ES2187783T3/es not_active Expired - Lifetime
- 1997-06-16 TR TR1998/02661T patent/TR199802661T2/xx unknown
- 1997-06-16 WO PCT/EP1997/003156 patent/WO1997048699A1/en not_active Application Discontinuation
- 1997-06-16 SK SK1752-98A patent/SK282706B6/sk unknown
- 1997-06-16 JP JP10502259A patent/JP2000512306A/ja active Pending
- 1997-06-16 EA EA199900043A patent/EA001780B1/ru not_active IP Right Cessation
- 1997-06-16 AU AU32602/97A patent/AU718597B2/en not_active Ceased
- 1997-06-16 AT AT97928224T patent/ATE228514T1/de not_active IP Right Cessation
- 1997-06-16 IL IL12741797A patent/IL127417A0/xx unknown
- 1997-06-16 CN CN97197311A patent/CN1229408A/zh active Pending
- 1997-06-16 NZ NZ333229A patent/NZ333229A/xx unknown
- 1997-06-16 KR KR1019980710443A patent/KR20000022045A/ko not_active Application Discontinuation
- 1997-06-16 AP APAP/P/1998/001410A patent/AP9801410A0/en unknown
- 1997-06-16 CA CA002258240A patent/CA2258240A1/en not_active Abandoned
- 1997-06-16 CZ CZ984205A patent/CZ420598A3/cs unknown
- 1997-06-16 DE DE69717449T patent/DE69717449T2/de not_active Expired - Fee Related
- 1997-06-16 EP EP97928224A patent/EP0912554B1/en not_active Expired - Lifetime
- 1997-06-16 BR BR9709911A patent/BR9709911A/pt unknown
- 1997-06-16 HU HU9903439A patent/HUP9903439A3/hu unknown
- 1997-06-16 US US09/202,780 patent/US6369060B1/en not_active Expired - Fee Related
- 1997-06-16 PL PL97330796A patent/PL330796A1/xx unknown
- 1997-06-18 AP APAP/P/1997/001037A patent/AP745A/en active
- 1997-06-18 DZ DZ970100A patent/DZ2250A1/fr active
- 1997-06-18 AR ARP970102673A patent/AR008243A1/es unknown
- 1997-06-18 PE PE1997000510A patent/PE86698A1/es not_active Application Discontinuation
- 1997-06-18 MA MA24666A patent/MA24214A1/fr unknown
- 1997-06-19 TW TW086108551A patent/TW382015B/zh not_active IP Right Cessation
- 1997-06-19 ZA ZA975415A patent/ZA975415B/xx unknown
- 1997-06-20 ID IDP972126A patent/ID19433A/id unknown
- 1997-06-20 CO CO97034431A patent/CO4890847A1/es unknown
-
1998
- 1998-12-18 OA OA9800245A patent/OA10944A/en unknown
- 1998-12-18 NO NO985972A patent/NO985972D0/no unknown
-
1999
- 1999-01-15 BG BG103089A patent/BG103089A/xx unknown
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