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CO2019004203A2 - Compuestos del péptido tirosina tirosina cíclico con anticuerpo acoplado como moduladores de receptores de neuropéptido y - Google Patents

Compuestos del péptido tirosina tirosina cíclico con anticuerpo acoplado como moduladores de receptores de neuropéptido y

Info

Publication number
CO2019004203A2
CO2019004203A2 CONC2019/0004203A CO2019004203A CO2019004203A2 CO 2019004203 A2 CO2019004203 A2 CO 2019004203A2 CO 2019004203 A CO2019004203 A CO 2019004203A CO 2019004203 A2 CO2019004203 A2 CO 2019004203A2
Authority
CO
Colombia
Prior art keywords
tyrosine
compounds
cyclic
receptor modulators
peptide
Prior art date
Application number
CONC2019/0004203A
Other languages
English (en)
Inventor
Mark Macielag
Raymond J Patch
Rui Zhang
Martin A Case
Mark Wall
Yue-Mei Zhang
Shamina M Rangwala
James N Leonard
Raul C Camacho
Michael J Hunter
Katharine E D'aquino
Wilson Edwards
Ronald V Swanson
Wenying Jian
Ellen Chi
Original Assignee
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Publication of CO2019004203A2 publication Critical patent/CO2019004203A2/es

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Abstract

La presente invención comprende conjugados que comprenden un anticuerpo monoclonal conjugado con un péptido PYY cíclico. La invención se refiere, además, a composiciones farmacéuticas y a métodos para usarlas. Los conjugados novedosos son útiles para prevenir, tratar o corregir enfermedades y trastornos descritos en la presente descripción.
CONC2019/0004203A 2016-10-27 2019-04-26 Compuestos del péptido tirosina tirosina cíclico con anticuerpo acoplado como moduladores de receptores de neuropéptido y CO2019004203A2 (es)

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