CN220957216U - Sucking disc connects suitable for micro-fluidic chip - Google Patents

Abstract

The utility model discloses a sucking disc joint suitable for a microfluidic chip, which comprises: the device comprises a transfer tube, wherein one end of the transfer tube is integrally connected with a docking tray, and the docking tray is connected with a connecting port of a microfluidic chip in an adaptive manner; the adsorption disc is fixed on the outer side wall of the transfer tube and positioned at the outer side of the butt joint disc, and an adsorption fixing cavity is arranged between the inner side wall of the adsorption disc and the outer side wall of the butt joint disc; the ultraviolet curing optical adhesive layer is arranged in the adsorption fixing cavity and is used for connecting the transfer tube and the adsorption disc on the microfluidic chip in a sealing way, and the novel microfluidic chip is simple in structure, convenient to fix, good in light transmittance, small in size and applicable to microfluidic chips made of various materials.

Description

A suction cup connector suitable for microfluidic chip

Technical Field

The utility model relates to the technical field of microfluidic chips, in particular to a suction cup joint suitable for a microfluidic chip.

Background technique

Microfluidics chip technology integrates the basic operating units of biological, chemical and medical analysis processes such as sample preparation, reaction, separation and detection into a micron-scale chip to automatically complete the entire analysis process. The microfluidic chip used is also called "laboratory on a chip" (lab-on-a-chip). It has been listed as one of the most important cutting-edge technologies in the 21st century. It has the advantages of small sample and reagent consumption, short analysis time, miniaturization and portability.

Connectors are one of the difficult problems in the preparation and application of microfluidic chips. The most commonly used materials in the preparation of microfluidic chips are polydimethylsiloxane (PDMS), polymethyl methacrylate (PMMA), glass and other materials. Stainless steel connectors are often used for connectors of PDMS chips, but such connectors are prone to leakage. Polyetheretherketone (PEEK) connectors are mainly used for glass and PMMA chips. However, these PEEK connectors are large in size, expensive, and have poor light transmittance.

Therefore, how to provide a connector that is small in size, has good light transmittance, is easy to fix, and is suitable for microfluidic chips made of a variety of different materials is a problem that those skilled in the art urgently need to solve.

Utility Model Content

In view of this, the utility model provides a suction cup connector suitable for a microfluidic chip, which can be quickly fixed on a connecting port of the microfluidic chip and has good sealing performance.

In order to achieve the above object, the utility model adopts the following technical solution: a suction cup connector suitable for a microfluidic chip, comprising:

A transfer tube, one end of which is integrally connected with a docking plate, and the docking plate is adapted to be connected with a connection port of the microfluidic chip;

An adsorption plate, the adsorption plate is fixed on the outer side wall of the transfer tube and is located outside the docking plate, and an adsorption fixing cavity is provided between the inner side wall of the adsorption plate and the outer side wall of the docking plate;

The ultraviolet curing optical adhesive layer is arranged in the adsorption fixing cavity and seals and connects the transfer tube and the adsorption plate to the microfluidic chip.

The beneficial effects of the utility model are as follows: a docking plate and an adsorption plate are provided, and the docking plate and the adsorption plate are arranged at the same end of the transfer tube, and the adsorption plate is located on the outside of the docking plate. When in use, the docking plate is docked with the connection port of the microfluidic chip, and pressed down with force to discharge the air in the adsorption fixing cavity between the adsorption plate and the docking plate, and a UV-curing optical adhesive layer is pre-coated in the adsorption fixing cavity, so that the optical adhesive is cured under ultraviolet light, so that the overall joint is firmly and sealedly connected to the microfluidic chip, and the air pressure difference and the optical adhesive are used for double fixation to achieve stable connection between the joint and the chip. Compared with PEEK joints and stainless steel joints, the novel suction cup joint is small in size, easy to fix, and suitable for microfluidic chips made of a variety of different materials.

Preferably, the adapter tube, docking plate and adsorption plate are integrally formed by 3D printing of transparent rubber material.

Preferably, the large-diameter end of the docking plate is coplanar with the large-diameter end of the adsorption plate.

Preferably, the outer diameter of the large-diameter end corresponding to the docking plate is larger than the inner diameter of the connecting port of the microfluidic chip.

BRIEF DESCRIPTION OF THE DRAWINGS

FIG1 is an overall structural diagram of a suction cup connector suitable for a microfluidic chip according to the present invention;

FIG2 is a second overall structural diagram of a suction cup connector suitable for a microfluidic chip according to the present invention;

FIG3 is an application diagram of a suction cup connector suitable for a microfluidic chip according to the present invention.

1 adapter tube, 2 docking plate, 3 adsorption plate, 4 adsorption fixing cavity, 5 UV curing optical adhesive layer, 6 microfluidic chip.

Detailed ways

The following will be combined with the drawings in the embodiments of the utility model to clearly and completely describe the technical solutions in the embodiments of the utility model. Obviously, the described embodiments are only part of the embodiments of the utility model, not all of the embodiments. Based on the embodiments in the utility model, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the utility model.

Referring to Figures 1 to 3 of the present invention, according to an embodiment of the present invention, a suction cup connector suitable for a microfluidic chip includes:

A transfer tube 1, one end of which is integrally connected with a docking plate 2, and the docking plate 2 is adapted to be connected with a connection port of a microfluidic chip 6;

The adsorption plate 3 is fixed on the outer wall of the transfer tube 1 and is located outside the docking plate 2. An adsorption fixing cavity 4 is provided between the inner wall of the adsorption plate 3 and the outer wall of the docking plate 2;

The UV-curable optical adhesive layer 5 is coated in the adsorption fixing cavity 4 and seals and connects the transfer tube 1 and the adsorption plate 3 to the microfluidic chip 6 .

Specifically, the outer diameter of the large-diameter end of the docking plate 2 is 3 mm; the outer diameter of the large-diameter end of the adsorption plate 3 is 7.8 mm; the outer diameter of the transfer tube 1 is 2 mm, and the inner diameter is 0.88 mm.

In other embodiments, the adapter tube 1, the docking plate 2 and the adsorption plate 3 are integrally formed by 3D printing of a transparent rubber material.

In some other specific embodiments, the large-diameter end of the docking plate 2 is coplanar with the large-diameter end of the adsorption plate 3 .

In some other embodiments, the outer diameter of the large-diameter end corresponding to the docking plate 2 is larger than the inner diameter of the connection port of the microfluidic chip 6, so that the docking plate 2 can cover the connection port of the microfluidic chip and ensure the sealing effect of the joint.

During specific installation and use, apply NOA81 optical glue in the adsorption fixing cavity, cover the microfluidic chip connection port with the inner docking plate, and then push it down to evacuate the air between the docking plate and the adsorption plate. At this time, the adsorption plate generates adsorption force under air pressure and cures the NOA81 optical glue under ultraviolet light, thereby sealing the suction cup joint as a whole and fixing it to the microfluidic chip.

The utility model can realize the rapid and simple preparation of the microfluidic chip connector, and the connector is small in size and does not interfere with the use of microfluidics; in addition, the connector is suitable for microfluidic chips made of various materials.

Three different hardness (30°, 50° and 70°) suction cup joints were prepared by 3D printing technology. The three different hardness joints were continuously injected at a flow rate of 1 mL/min for 48 hours in the same channel. The results showed that no leakage occurred in the three different hardness joints. The results show that joints with different hardness can be used to prepare microfluidic chip suction cup joints.

A 50° suction cup connector was selected and fixed to the same channel. The connector was injected continuously for 2 hours at flow rates of 1, 2, 3, 4, 5, 6, 7, and 8 mL/min. At these different flow rates, the 50° suction cup connector did not leak. The connector has good stability.

As for the device and the method of use disclosed in the embodiment, since they correspond to the method disclosed in the embodiment, the description is relatively simple, and the relevant parts can be referred to the description of the method part.

The above description of the disclosed embodiments enables those skilled in the art to implement or use the present invention. Various modifications to these embodiments will be apparent to those skilled in the art, and the general principles defined herein may be implemented in other embodiments without departing from the spirit or scope of the present invention. Therefore, the present invention will not be limited to the embodiments shown herein, but will conform to the widest scope consistent with the principles and novel features disclosed herein.

Claims (4)

1. A suction cup fitting for a microfluidic chip, comprising:

The device comprises a transfer tube (1), wherein one end of the transfer tube (1) is integrally connected with a butt joint disc (2), and the butt joint disc (2) is connected with a connecting port of a microfluidic chip (6) in an adaptive manner;

The adsorption disc (3), the adsorption disc (3) is fixed on the outer side wall of the transfer pipe (1) and is positioned at the outer side of the butt joint disc (2), and an adsorption fixing cavity (4) is arranged between the inner side wall of the adsorption disc (3) and the outer side wall of the butt joint disc (2);

The ultraviolet curing optical adhesive layer (5), the ultraviolet curing optical adhesive layer (5) is arranged in the adsorption fixing cavity (4) and is used for connecting the transfer tube (1) and the adsorption disc (3) on the microfluidic chip (6) in a sealing way.

2. The suction cup joint suitable for the microfluidic chip according to claim 1, wherein the adapter tube (1), the butt-joint disc (2) and the suction disc (3) are integrally formed by 3D printing of transparent rubber materials.

3. A suction cup fitting for microfluidic chips according to claim 1, characterized in that the large-caliber end of the docking plate (2) is coplanar with the large-caliber end of the adsorption plate (3).

4. The suction cup joint suitable for the microfluidic chip according to claim 1, wherein the external diameter size of the large-caliber end corresponding to the butt-joint disc (2) is larger than the internal diameter size of the connecting port of the microfluidic chip (6).