CN201732066U - Blood coagulation factor and blood platelet aggregation tester - Google Patents
Blood coagulation factor and blood platelet aggregation tester Download PDFInfo
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- CN201732066U CN201732066U CN2010202006071U CN201020200607U CN201732066U CN 201732066 U CN201732066 U CN 201732066U CN 2010202006071 U CN2010202006071 U CN 2010202006071U CN 201020200607 U CN201020200607 U CN 201020200607U CN 201732066 U CN201732066 U CN 201732066U
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Abstract
The utility model relates to a blood coagulation factor and blood platelet aggregation tester, which comprises a base, the base is provided with an automatic control circuit and a matched program, a test bench top of the base is provided with a blood coagulation factor test unit, a blood platelet aggregation test unit, a cleaning disk unit, a reagent bottle unit and a sample disk unit, and a blood platelet aggregation sample-adding needle unit, a cleaning needle unit, a blood coagulation factor blood sample needle unit and a blood coagulation factor reagent needle unit are arranged over the test bench top. Downward discharge type blood platelet aggregation test cups are adopted in the tester, so that a whole set of sample-adding, testing, cleaning, waste liquid-discharging, drying actions is automatically and integrally controlled; because a novel vertical traveling mechanism design is adopted, the workload of a traveling unit is effectively decreased, the precision of the automated operation of a sample-adding needle and a cleaning needle is increased, and the working efficiency is increased.
Description
Technical field
The utility model relates to a kind of clotting factor and platelet aggregation tester, described tester comprises clotting factor proving installation, platelet aggregation proving installation, cleaning disc device, reagent bottle device, sample disc device, platelet aggregation sample needle and needle cleaning device, clotting factor blood sample pin and clotting factor reagent needles device, described platelet aggregation sample needle, clotting factor blood sample pin and clotting factor reagent needles are connected with automatic application of sample pipeline, and described cleaning needle is connected with automatic detergent line.
Background technology
Chinese patent 90207370.2 discloses intelligent platelet aggregation instrument, comprises that complete machine is made up of power supply, temperature-adjusting circuit, photoelectric switching circuit, amplifying circuit, programmable amplifying circuit, analog to digital conversion circuit, data converting circuit, imput output circuit, display, keyboard, printer, stirring motor and basic calculating system.Make central processing unit by 8-bit microprocessor, the control each several part has functions such as the automatic zero set (AZS) of test blood plasma, stirring, reporting printing and demonstration time.Adopt the micro computer special circuit that various corresponding control programs are solidificated in the integrated circuit, solve automatic zero set (AZS), different specimen blood plasma is carried out automatic zero set (AZS); Automatically drive stirring motor, and the gathering curve and the laboratory report of test can be printed automatically, duplicated and show at that time time automatically.But this patent once only can be measured a blood sample, the category that belongs to hand dipping not only can cause the prolongation of test period, also can be because of artificial negligence of operation, influence precision of test result, operating personnel are because of directly contacting contaminated with patient's blood sample.Mostly common in the market test clotting factor instrument is to utilize the optical method principle to test, but this kind method very easily is subjected to the interference of sample turbidity; Therefore, need to propose a kind of new clotting factor and platelet aggregation tester in order to address the above problem.
Summary of the invention
The purpose of this utility model is to provide a kind of clotting factor and platelet aggregation tester, this tester is according to double magnetic circuit paramagnetic particle method test clotting factor, according to photoelectric turbidimetry test platelet aggregation, described tester comprises the clotting factor proving installation, the platelet aggregation proving installation, the cleaning disc device, the reagent bottle device, the sample disc device, platelet aggregation sample needle and needle cleaning device, clotting factor blood sample pin and clotting factor reagent needles device, described platelet aggregation sample needle, clotting factor blood sample pin is connected with automatic application of sample pipeline with the clotting factor reagent needles, and described cleaning needle is connected with automatic detergent line; Tester of the present utility model; operating personnel have been avoided because of directly contacting contaminated with patient's blood sample; protected greatly that the operator's is healthy; all application of sample program, test procedure, cleaning procedure are finished automatically by instrument, have improved the test speed and the accuracy of clinical examination greatly.
The purpose of this utility model is realized by following technical proposals: a kind of clotting factor and platelet aggregation tester, a support is arranged, support is provided with automatic control circuit and matcher, and the testing stand of described support is provided with clotting factor proving installation, platelet aggregation proving installation, cleaning disc device, reagent bottle device, sample disc device; Be provided with a plurality of platelet aggregation test cups in the described platelet aggregation proving installation, the detection light path device be set, comprise the lighting transistor circuit and the photoelectric switching circuit of complete configuration in this detection light path device around this platelet aggregation test cup; Below the described platelet aggregation test cup magnetic stirring apparatus is set; A plurality of sample cups hole is set on the described sample disc device; Comprise cleaning fluid bottle and waste collection bottle in the described cleaning disc device; On the described reagent bottle device low temperature holding device is set; Described clotting factor proving installation middle part is provided with a plurality of tactic preheating positions in storehouse and detects position in storehouse, and described detection position in storehouse symmetria bilateralis is provided with two groups of drive coils, and described detection position in storehouse below is provided with the measurement coil; Described testing stand top is provided with platelet aggregation sample needle device, needle cleaning device, clotting factor blood sample needle device, clotting factor reagent needles device, described platelet aggregation sample needle device, needle cleaning device, clotting factor blood sample needle device, clotting factor reagent needles device are installed on the application of sample running gear, this application of sample running gear comprise vertical travel mechanism, laterally travel mechanism, vertically to travel mechanism; Platelet aggregation sample needle on the described application of sample running gear, clotting factor blood sample pin and clotting factor reagent needles are connected with automatic application of sample pipeline, and the cleaning needle on the described application of sample running gear is connected with automatic detergent line; Described support top is provided with the conveyer of clotting factor test cup, and the conveyer of described clotting factor test cup comprises and is positioned at grabbing cup device and being positioned at the winding conveying device of clotting factor proving installation one side of clotting factor proving installation top; The described cup device of grabbing is installed in one and grabs on glass running gear, and this is grabbed a glass running gear and comprises horizontal running mechanism, vertical travel mechanism; Described winding conveying device is provided with clotting factor test cup band, and this winding conveying device below is provided with delivery chute, and the output terminal of described delivery chute extends to and the corresponding position of preheating position in storehouse, conveying device is housed below the described delivery chute.
Compared with the prior art the utility model has following advantage:
1, the utility model adopts emission type platelet aggregation test cup down, makes application of sample, stirring, detection, cleaning, removal waste fluid, dry entire exercise form the integral body of a robotization control.
2, the utility model can be tested clotting factor and test platelet aggregation simultaneously, and the whole robotizations of one-machine-multi-function have improved the test speed of clinical examination greatly.
3, the utility model adopts novel vertically designing to travel mechanism, has alleviated the weight of vertical travel mechanism effectively, has improved the automatically working precision of sample needle and cleaning needle, has improved work efficiency.
4, the utility model can automatically carry out clotting factor test and platelet aggregation test; operating personnel are being avoided because of directly contacting contaminated risk with patient's blood sample; protect the healthy of operator greatly, simultaneously also avoided the operator pollution of blood sample to be influenced the accuracy of detection.
Description of drawings
The utility model is described in further detail below in conjunction with drawings and Examples.
Fig. 1 is a structural representation of the present utility model
Fig. 2 is a plan structure synoptic diagram of the present utility model
Fig. 3 is a vertical structural representation (A-A cut-open view among Fig. 2) to travel mechanism in the utility model
Fig. 4 is the structural representation (partial sectional view) of vertical travel mechanism in the utility model
Fig. 5 is the structural representation (cut-open view) of platelet aggregation test cup in the utility model
Fig. 6 is the structural representation of winding conveying device in the utility model
Fig. 7 is a piping diagram of the present utility model
Embodiment
Referring to Fig. 1, Fig. 2, Fig. 3, (Fig. 1 show be the situation of removing the tester front panel) shown in Figure 4, clotting factor of the present utility model and platelet aggregation tester, a support 1 is arranged, support is provided with automatic control circuit and matcher, and the testing stand 2 of described support is provided with clotting factor proving installation 3 (this proving installation configuration double magnetic circuit paramagnetic particle method test circuit), platelet aggregation proving installation 4 (this proving installation configuration photoelectric turbidimetry test circuit), cleaning disc device 5, reagent bottle device 6, sample disc device 7; Be provided with a plurality of platelet aggregation test cups 401 in the described platelet aggregation proving installation, the detection light path device be set, comprise the lighting transistor circuit and the photoelectric switching circuit of complete configuration in this detection light path device around this platelet aggregation test cup; Below the described platelet aggregation test cup magnetic stirring apparatus is set; A plurality of sample cups hole 701 is set on the described sample disc device; Comprise cleaning fluid bottle 501 and waste collection bottle 502 in the described cleaning disc device; On the described reagent bottle device low temperature holding device is set; Described clotting factor proving installation middle part is provided with a plurality of tactic preheating positions in storehouse 302 and detects position in storehouse 301, and described detection position in storehouse symmetria bilateralis is provided with two groups of drive coils, is provided with one group under the described detection position in storehouse and measures coil; Described testing stand top is provided with platelet aggregation sample needle device, needle cleaning device, clotting factor blood sample needle device, clotting factor reagent needles device, described platelet aggregation sample needle device, needle cleaning device, clotting factor blood sample needle device, clotting factor reagent needles device are installed on the application of sample running gear 9, this application of sample running gear comprise vertical travel mechanism 901, laterally travel mechanism 902, vertically to travel mechanism 903; Be provided with clotting factor blood sample pin in the clotting factor blood sample needle device on the described application of sample running gear, be provided with the clotting factor reagent needles in the clotting factor reagent needles device, be provided with the platelet aggregation sample needle in the platelet aggregation sample needle device, be provided with cleaning needle in the needle cleaning device, described clotting factor blood sample pin 801, clotting factor reagent needles 802, platelet aggregation sample needle 803, is connected with application of sample pipeline automatically, described cleaning needle 804 is connected with automatic detergent line; Described support top is provided with the conveyer of clotting factor test cup, and the conveyer of described clotting factor test cup comprises and is positioned at grabbing cup device 304 and being positioned at the winding conveying device 303 of clotting factor proving installation one side of clotting factor proving installation top; The described cup device of grabbing is installed in one and grabs on glass running gear, and this is grabbed a glass running gear and comprises horizontal running mechanism, vertical travel mechanism; Described winding conveying device is provided with clotting factor test cup and is with 305, and this winding conveying device below is provided with delivery chute 306, and the output terminal of described delivery chute extends to and the corresponding position of preheating position in storehouse, conveying device is housed below the described delivery chute.
In the present embodiment, double magnetic circuit paramagnetic particle method test circuit and photoelectric turbidimetry test circuit adopt prior art, are not described in detail.Computer Control Technology is adopted in control of the present utility model, and its control circuit adopts the routine techniques means, is not described in detail.
Referring to (Fig. 2 show be the situation of removing the tester top board) shown in Figure 2, in the present embodiment, be provided with 4 platelet aggregation test cup positions in the platelet aggregation proving installation, platelet aggregation test cup 401 is plugged on the platelet aggregation test cup position, can take out easily and insert, below the platelet aggregation test cup magnetic stirring apparatus is set, in platelet aggregation test cup, add a little bar magnet, magnetic agitation motor-driven disk rotates, little bar magnet rotates at any time, realizes stirring the effect of plasma sample in the platelet aggregation test cup; Belong to prior art, be not described in detail.The utility model carries out the platelet aggregation test according to photoelectric turbidimetry, the lighting transistor circuit and the photoelectric switching circuit that comprise complete configuration in the used detection light path device, comprise an infrarede emitting diode in the lighting transistor circuit, comprise an infrared receiving crystal pipe in the photoelectric switching circuit, cup one side of platelet aggregation test cup is provided with infrarede emitting diode, and a corresponding survey is provided with infrared receiving crystal pipe (owing to being not show among the prior art figure).For platelet aggregation test cup after cleaning is in time dried, below platelet aggregation test cup, a heating arrangement is set, this heating arrangement is a heating wiring board, generate heat by the lead on this wiring board, be used to reach the effect that makes test zone keep 37 ℃ of constant temperature, and to the platelet aggregation test cup oven dry in time after cleaning.
Referring to Fig. 1, Fig. 2, shown in Figure 6, in the present embodiment, 4-12 preheating position in storehouse of test platform middle part series arrangement of clotting factor proving installation, 4 detection positions in storehouse, detect the position in storehouse symmetria bilateralis two groups of drive coils are set, there is electromagnet drive coil inside, can produce magnetic field after the electromagnet energising.Under detecting position in storehouse one group of measurement coil is set, the measurement coil is a hot-wire coil; Below preheating position in storehouse and detection position in storehouse a heating arrangement is set, this heating arrangement is a heating wiring board, by the heating of the lead on this wiring board, is used to reach the effect that makes test zone keep 37 ℃ of constant temperature.The conveyer of clotting factor test cup comprises and is positioned at grabbing cup device and being positioned at the winding conveying device of clotting factor proving installation one side of clotting factor proving installation top; The described cup of grabbing is equipped with a pedestal, and pedestal top is provided with an electromagnetic driver, and described pedestal bottom is provided with a pair of body that grasps, and described two grasp on the body to be provided with and grasp spring; Described concrete structure of grabbing cup device can be with reference to disclosed content in the Chinese patent 200920107535.3.The described cup device of grabbing is installed in one and grabs on glass running gear, and this is grabbed and comprises horizontal running mechanism, vertical travel mechanism on glass running gear; Described horizontal running mechanism comprises horizontally disposed slide rail, stepper motor, synchronous cog belt, walking in a horizontal state carriage; Described vertical travel mechanism comprises the slide rail, stepper motor, synchronous cog belt of vertical setting, the vertical carriage of walking; Described winding conveying device is provided with clotting factor test cup and is with 305, and described clotting factor test cup one by one is contained on the long transparent base band in advance.The shape of clotting factor test cup can be referring to Chinese patent 200930126003.X, and clotting factor test cup is up big and down small prismatoid, base seal, and rectangular opening is opened on top, places a measuring steel ball in each clotting factor test cup.This winding conveying device below is provided with delivery chute, has in this delivery chute to press from both sides along the cup that pushes away that groove moves, and pushes away the cup folder and is provided with a U-shaped mouth, and the width of U-shaped mouth is slightly larger than the bottom width of clotting factor test cup.The output terminal of described delivery chute extends to and the corresponding position of preheating position in storehouse, belt conveyor is housed below the described delivery chute.Whole transportation process is sent unified instruction directs by programming controller and is finished, and all provide the motor of power to be stepper motor.
Referring to shown in Figure 5, the platelet aggregation test cup in the utility model is different with employed square platelet aggregation test cup in the prior art, and the cup end of platelet aggregation test cup of the prior art is sealed, and the utility model is open.In the present embodiment, platelet aggregation test cup comprises the transparent cup 402 of a pipe shape, and bottom of cup is provided with bottom outlet 403, installs back liquid pipe nipple 404 on the bottom outlet, and this liquid back pipe connects mouth and is connected with the liquid back pipe road.The utility model adopts pipe shape cup to be convenient to automatic cleaning, has eliminated the dead angle in the cup, improves cleaning degree, and simultaneously, pipe shape cup also helps the even stirring of little bar magnet to plasma sample.Adopt bottom outlet and liquid back pipe to connect mouth structure, can by control system realize platelet aggregation test cup externally by with the conversion of emissions status, make platelet aggregation instrument have the function of automatic washing, can be after having finished the blood sample test, raffinate is discharged in the waste collection bottle automatically, need not manually platelet aggregation test cup to be extracted to clean.
Referring to Fig. 1, shown in Figure 2, in the present embodiment, the cleaning disc device is provided with two independently service sinks, and a service sink is used for the cleaning of platelet aggregation sample needle and cleaning needle, and another service sink is used for the cleaning of clotting factor blood sample pin and clotting factor reagent needles.Service sink inside is provided with two pin hole shape rinse baths 503 and waste collection mouth 504, and the bottom is provided with the waste collection bottle, and the waste collection mouth is communicated with the waste collection bottle.Cleaning waste liquid and discarded blood plasma that platelet aggregation sample needle device, needle cleaning device, clotting factor blood sample needle device, clotting factor reagent needles device and test cup produce can be discharged in the waste collection bottle unified the collection.
Referring to Fig. 1, shown in Figure 2, in the present embodiment, reagent bottle device top is provided with reagent bottle hole 601, and its interpolation installed reagents bottle, described reagent bottle are divided into the platelet aggregation reagent bottle that is used to preserve the clotting factor reagent bottle of multiple clotting reagent and is used to preserve the platelet aggregation derivant.Get the temperature requirement of collection derivant and clotting reagent in order to satisfy blood platelet, in reagent bottle device bottom the low temperature holding device is set, this low temperature holding device comprises a semiconductor cooling device, this refrigerating plant is made of refrigeration circuit, heat radiator and fan, refrigeration circuit belongs to prior art, is not described in detail.
Referring to Fig. 1, shown in Figure 2, in the present embodiment, a plurality of sample cups hole 701 is set on the sample disc device, the sample cup hole is by the lineament layout, plug-in mounting has the sample cup of PRP (platelet rich plasma), PPP (platelet poor plasma) in the sample cup hole, and the sample needle device can be drawn to detect from sample cup and use plasma sample.After detecting end, sample cup is discarded.
Referring to Fig. 1, Fig. 3, Fig. 4, shown in Figure 7, in the present embodiment, described clotting factor blood sample needle device comprises clotting factor blood sample pin 801, flexible pipe, solenoid valve, suction pumps, measuring element; Described clotting factor reagent needles device comprises clotting factor reagent needles 802, flexible pipe, solenoid valve, suction pumps, measuring element; Described platelet aggregation sample needle device comprises platelet aggregation sample needle 803, flexible pipe, solenoid valve, suction pumps, measuring element; Described needle cleaning device comprises cleaning needle 804, flexible pipe, solenoid valve, suction pumps, measuring element; Said apparatus belongs to the prior art scope, is not described in detail
Referring to Fig. 1, Fig. 2, Fig. 3, shown in Figure 4, in the present embodiment, described application of sample running gear 9 comprise vertical travel mechanism, laterally travel mechanism, vertically to travel mechanism, described vertically (X-direction) travel mechanism comprises longitudinal rail, stepper motor, synchronous cog belt, the vertical carriage 910 of walking, and described vertical walking carriage fixedly mounts with synchronous cog belt; Described laterally (Y direction) travel mechanism comprises cross slide way, stepper motor, synchronous cog belt, the horizontal carriage 905 of walking, and described horizontal walking carriage fixedly mounts with synchronous cog belt; Describedly vertically comprise 4 vertically to 906,4 stepper motors 907 of 909,4 driving key axles of 904,4 synchronous cog belts of gangbar to (Z-direction) travel mechanism; 4 synchronous cog belt driving wheels 911 and 4 synchronous cog belt engaged wheels 912.Described horizontal travel mechanism is installed on vertical walking carriage; Vertically be installed on the horizontal walking carriage to travel mechanism; Described cross slide way one end is installed on described vertical walking carriage, at this cross slide way other end transversing gear fixture 908 is installed, and horizontal walking carriage is installed on this cross slide way; This laterally on walking carriage by in twos side by side mode be provided with 4 vertically to through hole, in described each through hole, all be coated with one vertically to gangbar, described clotting factor blood sample pin, the clotting factor reagent needles, platelet aggregation sample needle and cleaning needle be installed in respectively described 4 vertically on gangbar, described each synchronous cog belt all is vertically set in the described horizontal walking carriage, and vertically fixedly mount to gangbar with each, described each driving key axle installs with described each synchronous cog belt driving wheel respectively, this driving key axle one end is connected with described vertical walking carriage turns by bearing, the other end is rotationally connected by bearing and described transversing gear fixture, described each stepper motor all is arranged on described vertical walking carriage, each stepper motor respectively with described each driving key axle.Described horizontal walking carriage and driving key axle horizontal install, described 4 driving key axles all be arranged in parallel with cross slide way, the section configuration at described driving key axle two ends is circular, so that driving key axle and transversing gear fixture are rotationally connected, the section configuration of this driving key axle interlude is a rectangle, so that the driving key axle is connected with synchronous cog belt driving wheel key.Stepper motor rotates by the driving key axle and drives the synchronous cog belt rotation, vertically realizes independently moving up and down of sample needle and cleaning needle to the gangbar upper and lower displacement thereby this synchronous cog belt drives each.Be hollow vertically described in the present embodiment, so that the flexible pipe on clotting factor blood sample pin, clotting factor reagent needles, platelet aggregation sample needle and the cleaning needle passes through to gangbar.The installation relation of the vertical travel mechanism described in the utility model, cross slide way, stepper motor, synchronous cog belt and the carriage of laterally walking all belongs to prior art, is not described in detail.In traditional design, usually stepper motor is vertically mounted under the horizontal walking carriage, and drive vertically to the gangbar upper and lower displacement by lead screw transmission mechanism, though this kind structure is simple, but horizontal travel mechanism of the present utility model adopts the cantilever structure design, and need the stepper motor of installation many, if adopt this structure, increased the weight of horizontal walking carriage virtually, reduce the laterally kinematic accuracy of walking carriage, so this structure and be not suitable for clotting factor of the present utility model and the platelet aggregation tester; Vertical design to travel mechanism can well address this problem in employing the utility model.
Referring to shown in Figure 7, the pipeline 10 of present embodiment comprises automatic application of sample pipeline and detergent line automatically.Clotting factor blood sample pin 801, clotting factor reagent needles 802 and platelet aggregation sample needle 803 are connected with automatic application of sample pipeline respectively, this pipeline comprises solenoid valve, glass tube syringe pump 11, be used for drawing quantitative blood samples, inject platelet aggregation test cup from sample cup.The glass tube syringe pump is provided with three, is connected by pipeline with the clotting factor reagent needles with platelet aggregation sample needle, clotting factor blood sample pin respectively.The automatic detergent line of platelet aggregation sample needle, clotting factor blood sample pin and clotting factor reagent needles comprises cleaning fluid bottle 501, five-way valve 12, glass tube syringe pump, deposit has clear water in the washer bottle, is used to clean platelet aggregation sample needle, clotting factor blood sample pin and clotting factor reagent needles.Needle cleaning device is connected with automatic detergent line, and the automatic detergent line of cleaning needle 804 comprises washer bottle, T-valve, scavenging pump 13; Be used to clean platelet aggregation test cup.The liquid back pipe of platelet aggregation test cup 401 connects mouth and is connected with the liquid back pipe road, the liquid back pipe road comprises waste collection bottle 502, negative pressure pump 14, six-way valve 15, liquid level detection device, is used for platelet aggregation test cup raffinate, discarded blood plasma, cleans waste collection.
Principle of work of the present utility model is as follows:
Platelet aggregation is measured according to photoelectric turbidimetry, and clotting factor is measured according to the double magnetic circuit paramagnetic particle method, and determination step is:
A, collection blood samples of patients sample carry out anti-freezing to this blood sample and handle, and generate anticoagulated whole blood, with the anticoagulated whole blood centrifugal treating, and preparation platelet rich plasma and platelet poor plasma;
B, platelet rich plasma and the platelet poor plasma for preparing is placed in the sample disc device, sample number is set;
C, with the reagent bottle device that the platelet aggregation derivant for preparing and clotting reagent are put into automatic coagulation analyzer, cryopreservation is standby;
D, order blood are assembled sample needle and press examination criteria consumption absorption platelet poor plasma from described sample disc devices, inject the test cup of platelet aggregation proving installation, the platelet aggregation proving installation reads platelet poor plasma sample transmission data and storage automatically; Automatically platelet poor plasma is discharged from test cup bottom then, clean the test cup automatically;
E, order blood are assembled sample needle and press examination criteria consumption absorption platelet rich plasma from described sample disc devices, inject the test cup of platelet aggregation proving installation, the platelet aggregation proving installation reads platelet rich plasma sample transmission data and storage automatically, cleans blood then automatically and assembles sample needle;
F, order blood are assembled sample needle and press examination criteria consumption absorption platelet aggregation derivant from the reagent bottle devices, inject the test cup of platelet aggregation proving installation, the platelet aggregation proving installation reads the platelet rich plasma sample transmission data in the platelet aggregation forming process in the stipulated time automatically, describe to assemble curve and storage, automatically the platelet rich plasma sample is discharged from test cup bottom then, clean blood then automatically and assemble sample needle and test cup;
The blood clotting cup that the conveyer of G, blood clotting cup will contain steel ball is delivered on the preheating position in storehouse of blood coagulation proving installation, and application software is discerned sample number;
H, order blood coagulation blood sample pin are pressed the platelet poor plasma that the examination criteria consumption is drawn same patient from described sample disc device, inject the blood clotting cup, automatically the preheating platelet poor plasma;
The conveyer of I, blood clotting cup is delivered to the blood clotting cup on the detection position in storehouse of blood coagulation proving installation, drive steel ball continuous vibration at the bottom of the blood clotting cup, from the reagent bottle device, press the examination criteria consumption according to the mensuration project order clotting reagent pin of selecting and draw the reagent of selecting, inject selected blood clotting cup;
J, blood coagulation proving installation read the amplitude variations of steel ball automatically, determine solidifying point, and the clotting factor data of measuring are stored, and the conveyer of blood clotting cup abandons used blood clotting cup;
K, calculate the platelet aggregation rate of tested blood sample, the measurement result of platelet aggregation and clotting factor is generated test report according to the patient information of being imported.
In the present embodiment, the action of the data test of platelet aggregation and clotting factor is all undertaken by computer program control sequence.
Claims (6)
1. clotting factor and platelet aggregation tester, a support is arranged, support is provided with automatic control circuit, it is characterized in that, the testing stand of described support is provided with clotting factor proving installation, platelet aggregation proving installation, cleaning disc device, reagent bottle device, sample disc device; Be provided with a plurality of platelet aggregation test cups in the described platelet aggregation proving installation, the detection light path device be set, comprise the lighting transistor circuit and the photoelectric switching circuit of complete configuration in this detection light path device around this platelet aggregation test cup; Below the described platelet aggregation test cup magnetic stirring apparatus is set; A plurality of sample cups hole is set on the described sample disc device; Comprise cleaning fluid bottle and waste collection bottle in the described cleaning disc device; On the described reagent bottle device low temperature holding device is set; Described clotting factor proving installation middle part is provided with a plurality of tactic preheating positions in storehouse and detects position in storehouse, and described detection position in storehouse symmetria bilateralis is provided with two groups of drive coils, and described detection position in storehouse below is provided with the measurement coil; Described testing stand top is provided with platelet aggregation sample needle device, needle cleaning device, clotting factor blood sample needle device, clotting factor reagent needles device, described platelet aggregation sample needle device, needle cleaning device, clotting factor blood sample needle device, clotting factor reagent needles device are installed on the application of sample running gear, this application of sample running gear comprise vertical travel mechanism, laterally travel mechanism, vertically to travel mechanism; Platelet aggregation sample needle on the described application of sample running gear, clotting factor blood sample pin and clotting factor reagent needles are connected with automatic application of sample pipeline, and the cleaning needle on the described application of sample running gear is connected with automatic detergent line; Described support top is provided with the conveyer of clotting factor test cup, and the conveyer of described clotting factor test cup comprises and is positioned at grabbing cup device and being positioned at the winding conveying device of clotting factor proving installation one side of clotting factor proving installation top; The described cup device of grabbing is installed in one and grabs on glass running gear, and this is grabbed a glass running gear and comprises horizontal running mechanism, vertical travel mechanism; Described winding conveying device is provided with clotting factor test cup band, and this winding conveying device below is provided with delivery chute, and the output terminal of described delivery chute extends to and the corresponding position of preheating position in storehouse, conveying device is housed below the described delivery chute.
2. clotting factor according to claim 1 and platelet aggregation tester is characterized in that, described vertical travel mechanism comprises longitudinal rail, stepper motor, synchronous cog belt, the vertical carriage of walking; Described horizontal travel mechanism comprises cross slide way, stepper motor, synchronous cog belt, the horizontal carriage of walking; Vertically comprise 4 vertically to gangbar, 4 driving key axles, 4 stepper motors, 4 synchronous cog belts, 4 synchronous cog belt driving wheels and 4 synchronous cog belt engaged wheels to travel mechanism, described horizontal travel mechanism is installed on vertical walking carriage; Vertically be installed on the horizontal walking carriage to travel mechanism; Described cross slide way one end is installed on described vertical walking carriage, and this cross slide way other end is equipped with the transversing gear fixture, and horizontal walking carriage is installed on this cross slide way; Laterally be provided with 4 vertically to gangbar on the walking carriage at this, described clotting factor blood sample needle device, clotting factor reagent needles device, platelet aggregation sample needle device and needle cleaning device be installed in respectively described 4 vertically on gangbar, described each synchronous cog belt all is arranged in the described horizontal walking carriage, and vertically fixedly mount to gangbar with each, described each driving key axle respectively with described each synchronous cog belt on driving wheel install, this driving key axle one end is connected with described vertical walking carriage turns, the other end and described transversing gear fixture are rotationally connected, described each stepper motor all is arranged on described vertical walking carriage, and installs with described each driving key axle.
3. clotting factor according to claim 1 and platelet aggregation tester, it is characterized in that described platelet aggregation test cup comprises the transparent cup of a pipe shape, bottom of cup is provided with bottom outlet, install back the liquid pipe nipple on the bottom outlet, this liquid back pipe connects mouth and is connected with the liquid back pipe road.
4. clotting factor according to claim 1 and platelet aggregation tester is characterized in that, a heating arrangement are set below the described platelet aggregation test cup.
5. clotting factor according to claim 1 and platelet aggregation tester is characterized in that, in reagent bottle device bottom the low temperature holding device are set, and this low temperature holding device comprises a semiconductor cooling device.
6. clotting factor according to claim 1 and platelet aggregation tester is characterized in that, below described preheating position in storehouse and detection position in storehouse a heating arrangement are set.
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CN102262090A (en) * | 2010-05-24 | 2011-11-30 | 北京普利生仪器有限公司 | Method and equipment for measuring platelet aggregation and blood coagulation factor |
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CN104931460A (en) * | 2014-03-18 | 2015-09-23 | 北京泰利康信科技有限公司 | Method for improving stability of platelet aggregation index |
CN105938096A (en) * | 2015-03-02 | 2016-09-14 | 山东泰利信医疗科技有限公司 | Method for determination of platelet aggregation rate |
CN109444441A (en) * | 2018-12-19 | 2019-03-08 | 江苏鸿恩医疗器械有限公司 | Automatic coagulation analyzer |
CN113574392A (en) * | 2019-01-11 | 2021-10-29 | 迈恩医疗解决方案有限公司 | Pipetting device and method for liquid transfer |
CN115266647A (en) * | 2022-08-04 | 2022-11-01 | 长春星锐智能化科技有限公司 | Full-automatic turbidity sampling device and using method |
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2010
- 2010-05-24 CN CN2010202006071U patent/CN201732066U/en not_active Expired - Fee Related
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CN102262090B (en) * | 2010-05-24 | 2012-09-12 | 北京普利生仪器有限公司 | Method and equipment for measuring platelet aggregation and blood coagulation factor |
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CN105938096A (en) * | 2015-03-02 | 2016-09-14 | 山东泰利信医疗科技有限公司 | Method for determination of platelet aggregation rate |
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