CN206404586U - A kind of digestion instrument of space hydrogen peroxide - Google Patents
A kind of digestion instrument of space hydrogen peroxide Download PDFInfo
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- CN206404586U CN206404586U CN201621487140.7U CN201621487140U CN206404586U CN 206404586 U CN206404586 U CN 206404586U CN 201621487140 U CN201621487140 U CN 201621487140U CN 206404586 U CN206404586 U CN 206404586U
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- Prior art keywords
- hydrogen peroxide
- enzyme preparation
- space
- pipeline
- fog
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- MHAJPDPJQMAIIY-UHFFFAOYSA-N Hydrogen peroxide Chemical compound OO MHAJPDPJQMAIIY-UHFFFAOYSA-N 0.000 title claims abstract description 85
- 230000029087 digestion Effects 0.000 title claims abstract description 15
- 102000004190 Enzymes Human genes 0.000 claims abstract description 42
- 108090000790 Enzymes Proteins 0.000 claims abstract description 42
- 238000002360 preparation method Methods 0.000 claims abstract description 33
- 239000007921 spray Substances 0.000 claims abstract description 24
- 238000003860 storage Methods 0.000 claims abstract description 7
- 230000001954 sterilising effect Effects 0.000 claims description 10
- 238000001914 filtration Methods 0.000 claims description 5
- 239000000443 aerosol Substances 0.000 abstract description 7
- 239000002245 particle Substances 0.000 abstract description 4
- 238000005265 energy consumption Methods 0.000 abstract description 3
- 239000007789 gas Substances 0.000 abstract description 3
- 230000005611 electricity Effects 0.000 abstract description 2
- 230000036541 health Effects 0.000 abstract description 2
- OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 description 12
- 238000004659 sterilization and disinfection Methods 0.000 description 10
- 238000009423 ventilation Methods 0.000 description 8
- 150000002978 peroxides Chemical class 0.000 description 6
- 239000000645 desinfectant Substances 0.000 description 5
- 238000002474 experimental method Methods 0.000 description 5
- 102000016938 Catalase Human genes 0.000 description 4
- 108010053835 Catalase Proteins 0.000 description 4
- JPVYNHNXODAKFH-UHFFFAOYSA-N Cu2+ Chemical compound [Cu+2] JPVYNHNXODAKFH-UHFFFAOYSA-N 0.000 description 4
- 230000008859 change Effects 0.000 description 4
- 229910001431 copper ion Inorganic materials 0.000 description 4
- 230000000694 effects Effects 0.000 description 4
- 230000006872 improvement Effects 0.000 description 4
- 238000004378 air conditioning Methods 0.000 description 3
- 239000000463 material Substances 0.000 description 3
- 238000000034 method Methods 0.000 description 3
- 238000005507 spraying Methods 0.000 description 3
- 241000193830 Bacillus <bacterium> Species 0.000 description 2
- 241000726221 Gemma Species 0.000 description 2
- 238000000889 atomisation Methods 0.000 description 2
- LOKCTEFSRHRXRJ-UHFFFAOYSA-I dipotassium trisodium dihydrogen phosphate hydrogen phosphate dichloride Chemical compound P(=O)(O)(O)[O-].[K+].P(=O)(O)([O-])[O-].[Na+].[Na+].[Cl-].[K+].[Cl-].[Na+] LOKCTEFSRHRXRJ-UHFFFAOYSA-I 0.000 description 2
- 238000005516 engineering process Methods 0.000 description 2
- 208000015181 infectious disease Diseases 0.000 description 2
- 230000002147 killing effect Effects 0.000 description 2
- NUJOXMJBOLGQSY-UHFFFAOYSA-N manganese dioxide Chemical compound O=[Mn]=O NUJOXMJBOLGQSY-UHFFFAOYSA-N 0.000 description 2
- 239000002953 phosphate buffered saline Substances 0.000 description 2
- 239000000843 powder Substances 0.000 description 2
- 241000894006 Bacteria Species 0.000 description 1
- 206010011409 Cross infection Diseases 0.000 description 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 description 1
- OAICVXFJPJFONN-UHFFFAOYSA-N Phosphorus Chemical compound [P] OAICVXFJPJFONN-UHFFFAOYSA-N 0.000 description 1
- 230000002411 adverse Effects 0.000 description 1
- 230000008901 benefit Effects 0.000 description 1
- 230000033228 biological regulation Effects 0.000 description 1
- 239000000872 buffer Substances 0.000 description 1
- 230000015556 catabolic process Effects 0.000 description 1
- 239000003054 catalyst Substances 0.000 description 1
- 230000003013 cytotoxicity Effects 0.000 description 1
- 231100000135 cytotoxicity Toxicity 0.000 description 1
- 238000005202 decontamination Methods 0.000 description 1
- 230000003588 decontaminative effect Effects 0.000 description 1
- 230000007812 deficiency Effects 0.000 description 1
- 238000006731 degradation reaction Methods 0.000 description 1
- 230000000249 desinfective effect Effects 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 239000012895 dilution Substances 0.000 description 1
- 238000010790 dilution Methods 0.000 description 1
- 238000006073 displacement reaction Methods 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 235000013399 edible fruits Nutrition 0.000 description 1
- 238000011049 filling Methods 0.000 description 1
- 238000003958 fumigation Methods 0.000 description 1
- 230000000855 fungicidal effect Effects 0.000 description 1
- 239000003365 glass fiber Substances 0.000 description 1
- 239000003292 glue Substances 0.000 description 1
- 230000009036 growth inhibition Effects 0.000 description 1
- 231100000206 health hazard Toxicity 0.000 description 1
- 229910052739 hydrogen Inorganic materials 0.000 description 1
- 239000001257 hydrogen Substances 0.000 description 1
- 150000008040 ionic compounds Chemical class 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 244000005700 microbiome Species 0.000 description 1
- 239000003595 mist Substances 0.000 description 1
- 238000012856 packing Methods 0.000 description 1
- 239000008363 phosphate buffer Substances 0.000 description 1
- 229910052698 phosphorus Inorganic materials 0.000 description 1
- 239000011574 phosphorus Substances 0.000 description 1
- XNGIFLGASWRNHJ-UHFFFAOYSA-L phthalate(2-) Chemical compound [O-]C(=O)C1=CC=CC=C1C([O-])=O XNGIFLGASWRNHJ-UHFFFAOYSA-L 0.000 description 1
- 231100000614 poison Toxicity 0.000 description 1
- 239000002574 poison Substances 0.000 description 1
- 230000008569 process Effects 0.000 description 1
- 238000012545 processing Methods 0.000 description 1
- 230000009467 reduction Effects 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- 238000007789 sealing Methods 0.000 description 1
- 238000004904 shortening Methods 0.000 description 1
- 239000000243 solution Substances 0.000 description 1
- 238000012360 testing method Methods 0.000 description 1
- 238000009834 vaporization Methods 0.000 description 1
- 230000008016 vaporization Effects 0.000 description 1
Classifications
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/20—Air quality improvement or preservation, e.g. vehicle emission control or emission reduction by using catalytic converters
Landscapes
- Apparatus For Disinfection Or Sterilisation (AREA)
- Food Preservation Except Freezing, Refrigeration, And Drying (AREA)
Abstract
The utility model discloses a kind of digestion instrument of space hydrogen peroxide, including be arranged in space to be cleared up fog-spray nozzle, be arranged at biologically digesting enzyme preparation pipeline and negative pressure the generation pipeline of fog-spray nozzle connected outside space, described biologically digesting enzyme preparation pipeline is connected with the storage tank of biologically digesting enzyme preparation, and described negative pressure produces pipeline and is connected with filter, flowmeter, pressure regulator valve, air compressor machine in turn from fog-spray nozzle one end.The utility model passes through the sprayable biologically digesting enzyme preparation of digestion instrument, can by biologically digesting enzyme preparation with less than specified particle diameter, the quick disperse of sterile aerosol shape in confined space, the concentration of hydrogen peroxide remained in closed environment can be reduced rapidly, without nuisance generation, recover environment utilization ratio, the harm to personnel health and environment is reduced, electricity, gas is saved, energy consumption is reduced.The utility model apparatus structure is simple, is easy to quick connection disassembling.
Description
Technical field
The utility model is related to a kind of Quick digestion device of space environment disinfectant, is based especially on gaseous state and dry fog mistake
After hydrogen oxide sterilization in rapid-digestion air residual hydrogen dioxide digestion instrument.
Background technology
Hydrogen peroxide is a kind of disinfectant efficiently, environmentally friendly.Environment is carried out using the hydrogen peroxide of vaporization or spray pattern
Fumigation, space especially closed to one carries out high level disinfection processing, it has also become one kind is by more and more widely used life
Thing decontamination measure.Generally with vaporized hydrogen peroxide (VHP), hydrogen peroxide steam (HPV) and hydrogen peroxide dry fog (HP-FOG) shape
Formula, by the field extensive use such as pharmaceuticals industry, bio-safety and hospital infection control, the sterilization of such as high-level clean room, part
Low temperature sterilizing and the terminal disinfection in the place such as ICU, ward online of pharmaceutical equipment, Biohazard Safety Equipment.It is this based on gaseous state or dry
The hydrogen peroxide of mist has stronger diffusivity and osmosis, therefore also has stronger fungicidal effectiveness.After treatment, disappeared
The hydrogen peroxide of higher concentration can be remained in poison ring border in longer time, health hazard can be produced to personnel, also can be to one
A little production activities and product quality have a negative impact, so as to influence to be sterilized the use of environment；On the other hand, when for biology
When the environment for learning experiment uses disinfectant with hydrogen peroxide, cytotoxicity, microorganism can be produced because of the presence of residual peroxide thing
Growth inhibition etc. influences the unfavorable factor of result of the test.Therefore, the quick hydrogen peroxide removed in environment is needed after sterilization, to drop
The adverse effect of low residual peroxide thing.
In existing removal air in the mode of residual hydrogen peroxide disinfectant, what is be widely used is carried out using air
Ventilation displacement or natural degradation method.Both modes, which exist, clears up that time-consuming, inefficiency and the problem of be difficult to cleared, this
Have a strong impact on the follow-up application for using, also therefore limiting this kind of disinfectant with hydrogen peroxide technology in processed region.
Also some similar researchs are directed to solving this problem, such as Chinese patent CN201310159540.X discloses one
Plant hydrogen peroxide steam and decompose filtering material, be that filling is golden using divalence is based between layer glass fiber air filtering material
Belong to ionic compound, such as manganese dioxide particulate filter is decomposed as catalyst, handled in the form of circulating filtration,
Root is it was found that partially long, the problem of energy consumption is big and less efficient that similarly there is digestion time.
The content of the invention
The utility model is that there is provided a kind of hydrogen peroxide is residual for deficiency present in solution prior art is cleared up in hydrogen peroxide
Stay and clear up thoroughly digestion instrument.
The utility model solve existing issue technical scheme method be：A kind of digestion instrument of space hydrogen peroxide, bag
Include the fog-spray nozzle being arranged in space to be cleared up, be arranged at the biologically digesting enzyme preparation pipeline and negative pressure that fog-spray nozzle is connected outside space
Pipeline is produced, described biologically digesting enzyme preparation pipeline is connected with the storage tank of biologically digesting enzyme preparation, and described negative pressure is produced
Pipeline is connected with filter, flowmeter, pressure regulator valve, air compressor machine in turn from fog-spray nozzle one end.
Removed as a further improvement, described biologically digesting enzyme preparation pipeline is located to be additionally provided between storage tank and fog-spray nozzle
Bacterium filter.
As a further improvement, described negative pressure generation pipeline, which is located at, is additionally provided with magnetic valve between pressure regulator valve and air compressor machine,
Described air compressor machine is provided with controller, described controller coordinate control magnetic valve and air compressor machine.
As a further improvement, described fog-spray nozzle is threadably secured on the bulkhead in space.
As a further improvement, described fog-spray nozzle by screw thread straight joint or snap joint connect negative pressure produce pipeline with
Biologically digesting enzyme preparation pipeline.
Compared with prior art, its advantage is to pass through the sprayable biologically digesting enzyme of digestion instrument to the utility model
Preparation, can be by biologically digesting enzyme preparation so that less than specified particle diameter, the quick disperse of sterile aerosol shape, in confined space, energy is fast
The concentration of hydrogen peroxide remained in the low closed environment of prompt drop, no nuisance generation, recovers environment utilization ratio, and reduction is strong to personnel
The harm of health and environment, saves electricity, gas, reduces energy consumption.The utility model apparatus structure is simple, is easy to quick connection disassembling.
Brief description of the drawings
Fig. 1 is device internal structure schematic diagram of the present utility model.
Fig. 2 is the structural representation of the utility model device.
Fig. 3 is the stereogram of the utility model device.
Embodiment
Referring to Fig. 1-3, the implementation case includes：The fog-spray nozzle 1 that is arranged in space to be cleared up, it is arranged at outside space and connects
The biologically digesting enzyme preparation pipeline 11 of fog-spray nozzle 1 produces pipeline 12 with negative pressure, and biologically digesting enzyme preparation pipeline 11 is connected with biology
The storage tank 8 of enzyme preparation is cleared up, negative pressure produces pipeline 12 and is connected with filter 2, flowmeter 3, pressure regulation in turn from the one end of fog-spray nozzle 1
Valve 4, air compressor machine 7.
Biologically digesting enzyme preparation pipeline 11, which is located at, is additionally provided with sterilizing filter 9 between storage tank 8 and fog-spray nozzle 1.
Negative pressure produces pipeline 12 and is provided with controller positioned at magnetic valve 5, air compressor machine 7 is additionally provided between pressure regulator valve and air compressor machine 7
6, controller 6 coordinates control magnetic valve 5 and air compressor machine 7.Fog-spray nozzle 1 is threadably secured on the bulkhead 13 in space.
Fog-spray nozzle 1 connects negative pressure by screw thread straight joint or snap joint and produces pipeline 12 and biologically digesting enzyme preparation pipeline
11.Above-mentioned each part as outside may be disposed in casing 14, and body 14 is by bolt or is welded to connect in space
Bulkhead 13 on.
Space such as when clearing up of the hydrogen peroxide of isolator nacelle, utilizes the present apparatus to spray biologically digesting enzyme preparation
Mode produces aerosol, the aerosol of atomization be suspended in particulate form disperse needed for clear up in space or sealing space, with
Brownian movement mode clears up gaseous state or dry fog state hydrogen peroxide in closed environment.
Wherein, every cubic metre of space spraying usage amount of biologically digesting enzyme preparation is 1~5ml.The aerosol particle grain of atomization
Footpath is less than 10 μm, in order to which aerosol particle suspends, can uniformly be mixed with residual peroxide thing.Aerosol is that sterile gas is molten
Glue, sprays as sterile spraying.
Biologically digesting enzyme preparation include per 100ml components 100mg~200mg catalases dry powder, volume ratio be 1%~
10% methanol, surplus are the phosphate buffer of pH6.0~8.0, and described biologically digesting enzyme preparation copper ion concentration is
Activity of catalase is 2000U/ml~3000U/ml in 1mmol/L~10mmol/L, biologically digesting enzyme preparation.
Preferably, methanol volume ratio is 2%；Catalase dry powder is 200mg, and copper ion concentration is 2mmol/L；Phosphorus
Phthalate buffer is pH 7.0, and the vigor of hydrogen peroxide enzyme preparation is 3000U/ml.
In order to reach aseptic result, the packing material of biologically digesting enzyme preparation can be positioned in space to be cleared up in advance.
1st, the hydrogen peroxide in air is cleared up after the completion of the sterilization of infection ward hydrogen peroxide steam.
1) carry out arranging residual using the air-conditioning system of traditional rooms.
Using portable vaporized hydrogen peroxide generator to 80m3Ward is infected, portable vaporized hydrogen peroxide generator
Run background environment condition：20~25 DEG C of temperature, relative humidity 60% carries out terminal disinfection, work using hydrogen peroxide steam
Parameter is set to：
Disinfecting process concentration of hydrogen peroxide change curve such as following table one, two, three.
After three experiments terminate, residual peroxide concentration is respectively 1.4mg/m inside infection ward3, 1.2mg/m3,
1.4mg/m3。
2) row of progress is residual by the way of ventilation is combined with biologically digesting enzyme, uses portable vaporized hydrogen peroxide generator
To 80m3Infecting ward, (equipment runs background environment condition：20~25 DEG C of temperature, relative humidity 60%) steamed using hydrogen peroxide
Vapour carries out terminal disinfection, and running parameter is set to：
The implementation case includes methanol volume ratio as 2% using every 100ml biologically digestings enzyme preparation, and copper ion concentration is
Exemplified by 2mmol/L, catalase 200mg, pH 7.0 phosphate buffered saline biologically digesting enzyme, and pass through degerming mistake
Filter.Sterilize and terminate and after the air-conditioning system ventilation of 30 minutes in room, be combined using ventilation with sprinkling biologically digesting enzyme
Mode, immixture 30 minutes, as a result such as following table：
Concentration of hydrogen peroxide change curve such as following table one, two, three.
3) from the point of view of the result of two groups of experiments, divulged information the side being combined with sprinkling biologically digesting enzyme using room air conditioning system
Formula can the row's of greatly shortening residual time.
2. clear up residual hydrogen dioxide in Sterilized isolator.
1) carry out arranging residual using draft type.
Bio-decontaminated is carried out using vaporized hydrogen peroxide in Sterilized isolator, to the stearothermophilus gemma with typical drag
Bacillus (ATCC#7953) reaches 6 logarithm killing effects, and it is residual with arranging to carry out sterilization cycle using following parameter：
Concentration of hydrogen peroxide change curve such as following table one, two, three.
After three experiments terminate, residual peroxide concentration is respectively 4.9mg/m inside Sterilized isolator nacelle3,
5.3mg/m3, 6.3mg/m3。
2) row of progress is residual by the way of ventilation is combined with biologically digesting enzyme.
Bio-decontaminated is carried out using vaporized hydrogen peroxide in Sterilized isolator, to the stearothermophilus gemma with typical drag
Bacillus (ATCC#7953) reaches the killing effect of 6 logarithms, and it is residual with arranging to carry out sterilization cycle using following parameter：
Methanol volume ratio is included as 2% using every 100ml biologically digestings enzyme preparation, copper ion concentration is 2mmol/L, peroxide
Exemplified by the phosphate buffered saline biologically digesting enzyme for changing hydrogen enzyme 200mg, pH 7.0, above-mentioned enzyme preparation is diluted to 10 times of dilutions
Liquid prepares biologically digesting enzyme preparation, and passes through aseptic filtration.Sterilizing is completed in isolator and after the ventilation of 30 minutes, is used
Ventilation is with spraying the mode that is combined of biologically digesting enzyme, in immixture after 10 minutes, nacelle internal residual concentration such as following table：
Concentration of hydrogen peroxide change curve such as following table one, two, three.
1) from the point of view of the result of two groups of experiments, it can be contracted significantly by the way of sprinkling biologically digesting enzyme is combined using ventilation
Short row's residual time, and row residual effect fruit is more thorough.
Claims (5)
1. a kind of digestion instrument of space hydrogen peroxide, it is characterised in that：Including be arranged in space to be cleared up fog-spray nozzle, set
It is placed in outside space the biologically digesting enzyme preparation pipeline for connecting fog-spray nozzle and negative pressure produces pipeline, described biologically digesting enzyme preparation pipe
Road is connected with the storage tank of biologically digesting enzyme preparation, and described negative pressure produces pipeline and is connected with filtering in turn from fog-spray nozzle one end
Device, flowmeter, pressure regulator valve, air compressor machine.
2. the digestion instrument of space hydrogen peroxide as claimed in claim 1, it is characterised in that：Described biologically digesting enzyme preparation
Pipeline, which is located at, is additionally provided with sterilizing filter between storage tank and fog-spray nozzle.
3. the digestion instrument of space hydrogen peroxide as claimed in claim 1, it is characterised in that：Described negative pressure produces pipeline position
Magnetic valve is additionally provided between pressure regulator valve and air compressor machine, described air compressor machine is provided with controller, described controller coordinate control
Magnetic valve and air compressor machine.
4. the digestion instrument of space hydrogen peroxide as claimed in claim 1, it is characterised in that：Described fog-spray nozzle passes through screw thread
On fixed in space bulkhead.
5. the digestion instrument of the space hydrogen peroxide as described in claim 1 or 4, it is characterised in that：Described fog-spray nozzle passes through
Screw thread straight joint or snap joint connection negative pressure produce pipeline and biologically digesting enzyme preparation pipeline.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201621487140.7U CN206404586U (en) | 2016-12-31 | 2016-12-31 | A kind of digestion instrument of space hydrogen peroxide |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201621487140.7U CN206404586U (en) | 2016-12-31 | 2016-12-31 | A kind of digestion instrument of space hydrogen peroxide |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN206404586U true CN206404586U (en) | 2017-08-15 |
Family
ID=59553008
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201621487140.7U Active CN206404586U (en) | 2016-12-31 | 2016-12-31 | A kind of digestion instrument of space hydrogen peroxide |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN206404586U (en) |
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2016
- 2016-12-31 CN CN201621487140.7U patent/CN206404586U/en active Active
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