CN1726985A - Medication for treating chronic appendages inflammation, and preparation method - Google Patents
Medication for treating chronic appendages inflammation, and preparation method Download PDFInfo
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- CN1726985A CN1726985A CN 200410070645 CN200410070645A CN1726985A CN 1726985 A CN1726985 A CN 1726985A CN 200410070645 CN200410070645 CN 200410070645 CN 200410070645 A CN200410070645 A CN 200410070645A CN 1726985 A CN1726985 A CN 1726985A
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Abstract
A medicine in the form of powder for treating chronic adnexitis is disclosed. Its advantages are high cure rate, quickly taking its effect, and no recurrence.
Description
Technical field:
The present invention relates to a kind of medicine for the treatment of chronic adnexitis and preparation method thereof, belong to the field of Chinese medicines.
Background technology:
In internal genital organs of female, fallopian tube, ovary are called as uterus adnexa.Adnexitis is meant the inflammation of fallopian tube and ovary.The most common with salpingitis, because the contiguous mutually relation of the region of anatomy, often salpingitis, oophoritis, pelvioperitonitis are simultaneously and deposit and influence each other.But fallopian tube, oophoritis usually are associated with the other inflammation of connective tissue in palace, pelvioperitonitis, and also are not easily distinguishable when diagnosis, and like this, pelvioperitonitis, the other inflammation of connective tissue in palace have just also been put under the adnexitis scope.The most common with salpingitis in inflammatory disease of pelvic organs, its pathogenic factor mainly contains:
(1) childbirth or post-abortion, whole then pelvic cavity caused inflammation because resistance descends, and pathogen is through the up infection of reproductive tract and be diffused into fallopian tube, ovary.
(2) in the intrauterine device extensive use, the patient does not note Personal hygiene, or operation technique is not strict, and many acute salpingo-oophoritises, pelvioperitonitis all are therefore to take place.
(3) uteroventral operation that carries out without strict sterilization, as uterine aspiration, hysterosalpingography, cervical canal treatment, and the undemanding obstetric operation infection etc. of sterilizing.
(4) do not note menstrual hygiene, menstrual phase sexual intercourse or unclean sexual intercourse etc.
When (5) other positions of health have infection without treatment in time, but the tuberculosis disease is more common in the capable propagation of pathogen menses and cause adnexitis.
When (6) pelvic cavity or fallopian tube adjacent organs are inflamed as appendicitis, can cause adnexitis, pelvioperitonitis by direct extension.Inflammation generally occurs in contiguous an oviductus lateralis and ovary.
(7) sexually transmitted disease (STD) such as gonorrhea, infecting the back gonorrhea diplococcus can cause fallopian tube, ovary inflammation along mucosa to vertical spread.
[clinical manifestation]
Chronic salpingitis, pelvioperitonitis are many, and treatment is not thoroughly or do not give and paying attention to due to the treatment when suffering from acute salpingo-oophoritis, pelvioperitonitis.Chronic inflammatory disease is shown effect repeatedly, and with the passing of time delay makes pelvic congestion, connective fiberization, and pelvic organ is inter-adhesive.Patient's hypogastric region pain that weigh down to expand is modal symptom, and often in menstrual period or tired postemphasis, leucorrhoea grow in quantity simultaneously, menstrual blood volume more or less, lumbosacral aching pain, part patient also can have sexual anhedonia.See retroflextion during gynecologial examination, movable poor, the uterus is other can lay one's hand on and increase thick fallopian tube, and tenderness is arranged.If there is inflammatory mass to form, can touch enclosed mass on side, palace or rear, uterus during inspection, movable bad, tenderness is arranged.Chronic salpingitis does not heal for a long time, can cause mucosa adhesion in the fallopian tube, makes salpingemphraxis, secondary sterility, or fallopian tube tube chamber incomplete obstruction, the chance of occurrence of increase ectopic pregnancy.When fimbriated extremity of fallopian during, hydrosalpinx can also occur, but the patient may there be obvious subjective symptoms because of the inflammation adhesion.
Disease is seen few abdomen one side or two side pain, touch by painful to add, the nodosity lump, painfully be stubborn, pull, thorn, angor, or lead the breast side of body on the distending pain, or attack pain, or heavy aching and tired, Gu cold, meet cold touch water make moist disgruntled, symptom aggravation, menstrual period, more so profuse leukorrhea, color were greasy in vain sticking or clear rare as water, menstrual cycle postpones also or shifts to an earlier date menstrual period or length or weak point, more or less mensis in amount, amenorrhea very then, purple coloured menses, dark, deceive, have piece.General Symptoms is seen tired cold physique or edema, and lumbago is aching and tired, anorexia, and emaciated physique, complexion is blue or green or white, or dark or ecchymosis etc.Trouble for a long time as these diseases, patient's life and work is caused very big adverse effect.
[pathogen and pathology of tcm]
Be mainly in for a long time especially and touch water in menstrual phase and front and back and make moist and suffer from cold, easily call together in the cold-damp exopathogen goes into, have a liking for raw food for a long time and get fed up, or use cold and cool medicine for a long time, the yang-energy of damage spleen sun and kidney, deficiency of spleen-YANG then loses the fortuneization the lucid yang sending up, and water paddy goes into stomach and becomes with cold-damp, insufficiency of kidney-YANG then lose warm rising gasification and cold-damp with life, the uterus of making a bet, the vessels of the uterus of living in a place other than one's hometown, the uterus is lost warm easier calling together and is subjected to the cold-damp exopathogen, inside and outside combined pathogens occupies vessels of the uterus for a long time, and QI and blood is held back with fixed attention and closed knot; Chamber is forfeited one's integrity and is lost cleanly, decreases kidney qi and void on foot, and void then intrauterine is kept outer imperial miopragia, or serious disease prolonged illness must reach kidney thoroughly, or reports the plain void of body kidney qi and also can cause in the pathogen to go into outside living; The angry utmost point of crossing of long-term disorder of emotion melancholy, depression of liver-QI then, the QI and blood that vessels of the uterus is subjected to is closed knot by resistance.Also or because of at the inflammation initial stage, acute stage prolongs to control to lose to be controlled, pathogen occupies for a long time and does not remove healthy energy consumption and cause this for a long time.This disease mostly is comprehensive pathological factor and forms, the spleen kidney yang deficiency of vital energy, and the cold-damp gas stasis of blood is tied mutually, excess caused by deficiency, because of real more empty, simulataneous insufficiency and excessive is the pathogenesis main points.Heavy when light when becoming eventually, outbreak increases the weight of gradually repeatedly, the difficult pertinacious disease that does not heal for a long time.Ooze out hypertrophy in the long-term tube chamber and form the tuberosity lump, from interior and outside, involve connective tissue on every side, lump prolongs and increases thick increase for a long time day by day, adhesion obturation, secondary cyst, infertile, diseases such as menstruation is not normal, leukorrhagia, abdomen are painful, pain in the lumbar region.
[treatment of chronic adnexitis]
The treatment of chronic adnexitis at present only is confined to treat energetically acute salpingo-oophoritis, pelvioperitonitis, occurs as key with the prevention primary disease.Note Personal hygiene and menstrual hygiene at ordinary times, the prevention chronic infection.Because of bigger hydrosalpinx or the tubo-ovarian cyst that inflammation causes, row operative treatment etc.Cause infertile person for salpingemphraxis, row fallopian tube reduction operation.Medicine to the listing at present of the chronic adnexitis of acute attack repeatedly is many with anti-inflammatory treatment, heat-clearing and toxic substances removing, it is turbid to remove humidifying, blood circulation promoting and blood stasis dispelling etc., in, the patent medicine treatment.Weak curative effect, easily recurrence is difficult to reach the purpose of effecting a permanent cure.
I observe experience genus cold-damp gas stasis of blood person through the several years and see that at most the course of disease is long, and that controls is difficult, and damp and hot person is more rare, and the course of disease is shorter, and that controls is easier.Temperature born of the same parents cold expelling, it is turbid to remove humidifying, depressed liver-energy dispersing and QI regulating, blood circulation promoting and blood stasis dispelling, the strong liver spleen kidney of temperature always is dissolved in a stove, is that method is wanted in the treatment of chronic adnexitis.Our by Fructus Foeniculi, Radix Linderae, Radix et Bulbus Allii tuberosi, Rhizoma Cyperi, Semen Vaccariae, Fructus Liquidambaris, Flos Carthami, Radix Angelicae Sinensis, Ramulus Cinnamomi is formed.The hot temperature of Fructus Foeniculi is gone into liver spleen kidney in the side, and direct reach few abdomen and reach vessels of the uterus, dispersing cold for relieving pain, by wet water stain, the kind chronic diarrhea of controlling, gate of vitality's fire is mended at warm public region; The hot temperature of Radix Linderae is gone into Liver and kidney and is walked vessels of the uterus, regulating QI to remove the stagnation, dispersing cold for relieving pain, warm liver the kidney warming; The sweet sad heat of Radix et Bulbus Allii tuberosi, by Chen Han, warming the liver kidney, fonifying life-gate fire, circulation of qi promoting dissipating blood stasis, three medicines close 5 and strengthen the cold expelling circulation of qi promoting by wet gesture, the power of strong liver spleen kidney yang gas.Rhizoma Cyperiization Yu Liqi is apt to help Radix Linderae Radix et Bulbus Allii tuberosi regulating QI to remove the stagnation, incorporates the gas in the blood promoting the circulation of blood into, and the capable then blood of gas is lived, blood then stasis of blood facilitation alive; Flos Carthami, Fructus Liquidambaris, Semen Vaccariae blood circulation promoting and blood stasis dispelling promote qi circulation opening warp, and Fructus Liquidambaris and energy diuretic eliminating dampness and arresting leucorrhea; Chinese angelica blood supplementing and blood are moisturized, and the kind stomachache lump in the abdomen of controlling, the Ramulus Cinnamomi dissipating fluid-retention that activates yang is gone into blood system, and warm promoting blood circulation.All medicines close Ji the gathering knot detumescence piece that looses altogether, and promoting blood circulation opens and closes clean mansion, consolidates and sets upright, and set upright in eliminating evil, and are eliminating evil in setting upright, and dispel and can't harm, mend and helpless evil eutopic reduction only.Even empty partially real very person's 5 optimum curative effect side's medicines with the tight plus-minus that cooperates flexibly, can pertinacious disease speed be healed.Though the flat drug effect of we's flavour of a drug is strong, no matter do not subtract with decoct, electuary or immersion curative effect.
[summary of the invention]
The inventor is through a large amount of lucubrates repeatedly.By a large amount of clinical practice checkings, found finally for many years, better curative effect has been arranged, the simple and direct nimble oral medicinal herb medicine of specially controlling chronic adnexitis, thus finished the present invention.We also can be widely used in the metritis that belongs to cold-damp gas blood stasis syndrome, cervical erosion, and hysteromyoma, diseases such as ovarian cyst are respond well.
[preparation method of this Chinese medicine composition]
Our by Fructus Foeniculi, Radix Linderae, Radix et Bulbus Allii tuberosi, Rhizoma Cyperi, Semen Vaccariae, Fructus Liquidambaris, Flos Carthami, Radix Angelicae Sinensis, Ramulus Cinnamomi is formed.The hot temperature of Fructus Foeniculi is gone into liver spleen kidney in the side, and direct reach few abdomen and reach vessels of the uterus, dispersing cold for relieving pain, by wet water stain, the kind chronic diarrhea of controlling, gate of vitality's fire is mended at warm public region; The hot temperature of Radix Linderae is gone into Liver and kidney and is walked vessels of the uterus, regulating QI to remove the stagnation, dispersing cold for relieving pain, warm liver the kidney warming; The hot temperature of Radix et Bulbus Allii tuberosi, by Chen Han, warming the liver kidney, fonifying life-gate fire, circulation of qi promoting dissipating blood stasis, three medicines close 5 and strengthen the cold expelling circulation of qi promoting by wet gesture, the power of strong liver spleen kidney yang gas.Rhizoma Cyperiization Yu Liqi is apt to help Radix Linderae Radix et Bulbus Allii tuberosi regulating QI to remove the stagnation, incorporates the gas in the blood promoting the circulation of blood into, and the capable then blood of gas is lived, blood then stasis of blood facilitation alive; Flos Carthami, Fructus Liquidambaris, Semen Vaccariae blood circulation promoting and blood stasis dispelling promote qi circulation opening warp, and Fructus Liquidambaris and energy diuretic eliminating dampness and arresting leucorrhea; Chinese angelica blood supplementing and blood are moisturized, and the kind stomachache lump in the abdomen of controlling, the Ramulus Cinnamomi dissipating fluid-retention that activates yang is gone into blood system, and warm promoting blood circulation.All medicines close Ji the gathering knot detumescence piece that looses altogether, and promoting blood circulation opens and closes clean mansion, consolidates and sets upright, and set upright in eliminating evil, and are eliminating evil in setting upright, and dispel and can't harm, mend and helpless evil eutopic reduction only.Even empty partially real very person's 5 optimum curative effect side's medicines with the tight plus-minus that cooperates flexibly, can pertinacious disease speed be healed.Though the flat drug effect of we's flavour of a drug is strong, no matter do not subtract with decoct, electuary or immersion curative effect.We also can be widely used in the metritis that belongs to cold-damp gas blood stasis syndrome, cervical erosion, and hysteromyoma, diseases such as ovarian cyst are respond well.
Fructus Foeniculi under among the present invention is the fruit of samphire Fructus Foeniculi Foeniculum vulgarc Mill (Latin).Radix Linderae is the root of canella Radix Linderae Lindera strychnifolia (Sieb.etZucc.) Villar (Latin).Radix et Bulbus Allii tuberosi Allium tuberosum Rottler (Latin) is the root and the bulb of liliaceous plant fragrant-flowered garlic.Rhizoma Cyperi is sedge dried tuber Cyperus rotundus L (Latin) rhizome.Semen Vaccariae is the seed of pinkwort Vaccaria segetalis, former plant Vaccaria segetalis Vaccariasegetalis (Neek.) Gareke (Latin).Fructus Liquidambaris is the fruit of Hamamelidaceae plant sweetgum, former plant sweetgum Liquidambar formo ana Hance (Latin).Flos Carthami is the flower of feverfew Flos Carthami Carthamus tinclorius L (Latin).When the root that is classified as umbelliferae angelica Angelicasinensis (Oliv.) Diels (Latin).
The preparation method of pharmaceutically active component of the present invention is as follows:
With the Fructus Foeniculi (do and fry) of described heavy reason proportioning, Radix Linderae, Radix et Bulbus Allii tuberosi, Rhizoma Cyperi (vinegar system), Semen Vaccariae, Fructus Liquidambaris, Flos Carthami, Radix Angelicae Sinensis (processed with wine), Ramulus Cinnamomi is formed.
Decoct: pulverize behind each the medicine mix homogeneously in the above prescription, decocting, each 20-30 gram was fried in shallow oil to 30 minutes, the slag clothes juice of dispelling after each amount of water did not have powder 3cm to be advisable to filter.
Electuary: will pulverize behind each the medicine mix homogeneously in the above prescription, with each 10 grams of medicine foam, 3 times on the one direct warm boiled waters.
Soaking agent: will pulverize behind each the medicine mix homogeneously in the above prescription,, directly soak clothes after 60 minutes with the boiled water immersion with each 10 grams of medicine foam-20 grams.1-2 time on the one.
The active constituent of medicine of the present invention, can add various conventional adjuvant required when making different dosage form, the method of Chinese medicinal conventional as disintegrating agent, lubricant, binding agent etc. can be prepared into any peroral dosage form commonly used, as pill, powder, tablet, capsule, oral liquid etc.
Medicine of the present invention has warm born of the same parents' cold expelling, and it is turbid to remove humidifying, depressed liver-energy dispersing and QI regulating, and the dissipating fluid-retention that activates yang, blood circulation promoting and blood stasis dispelling, the strong liver spleen kidney of temperature always is dissolved in a stove, is the optimal medicine of chronic adnexitis.
The specific embodiment:
Drug therapy chronic adnexitis of the present invention clinical observation
1, clinical data
Accept patient's 2000 examples for medical treatment, most of through the clinical examination diagnosis, part through the color ultrasound ultrasound diagnosis as diagnosis basis.
2, diagnostic criteria
(1) tcm diagnosis standard: disease is seen few abdomen one side or two side pain, touch by painful to add, the nodosity lump, painfully be stubborn, pull, thorn, angor, or lead the breast side of body on the distending pain, or attack pain, or heavy aching and tired, Gu cold, meet cold touch water make moist disgruntled, symptom aggravation, menstrual period, more so profuse leukorrhea, color were greasy in vain sticking or clear rare as water, menstrual cycle postpones also or shifts to an earlier date menstrual period or length or weak point, more or less mensis in amount, amenorrhea very then, purple coloured menses, dark, deceive, have piece.General Symptoms is seen tired cold physique or edema, and lumbago is aching and tired, anorexia, and emaciated physique, complexion is blue or green or white, or dark or ecchymosis etc., troubles for a long time as these diseases, and patient's life and work is caused very big adverse effect.
(2) Western medicine diagnose standard: it is modal symptom that patient's hypogastric region weighs down the pain that expands, and often in menstrual period or tired postemphasis, the while leucorrhoea grow in quantity, chronic salpingitis does not heal for a long time, can cause mucosa adhesion in the fallopian tube, make salpingemphraxis, secondary sterility, or fallopian tube tube chamber incomplete obstruction, the chance of occurrence of increase ectopic pregnancy.When fimbriated extremity of fallopian during, hydrosalpinx can also occur, but the patient may there be obvious subjective symptoms because of the inflammation adhesion.Menstrual blood volume more or less or amenorrhea, lumbosacral aching pain, part patient also can have sexual anhedonia.See retroflextion during gynecologial examination, movable poor, the uterus is other can lay one's hand on and increase thick fallopian tube, and tenderness is arranged.If there is inflammatory mass to form, can touch enclosed mass on side, palace or rear, uterus during inspection, movable bad, tenderness is arranged.
1. medical history chronic salpingitis, pelvioperitonitis many when suffering from acute salpingo-oophoritis, pelvioperitonitis treatment not thoroughly or do not give and paying attention to due to the treatment, chronic inflammatory disease is shown effect repeatedly, delay with the passing of time, make pelvic congestion, connective fiberization, pelvic organ is inter-adhesive, and the infertility history is arranged.2. classical symptom and sign menstrual blood volume more or less, lumbosacral aching pain, part patient also can have sexual anhedonia.See retroflextion during gynecologial examination, movable poor, the uterus is other can lay one's hand on and increase thick fallopian tube, and tenderness is arranged.If there is inflammatory mass to form, can touch enclosed mass on side, palace or rear, uterus during inspection, movable bad, tenderness is arranged.3. laboratory examination, visible numeration of leukocyte of routine test and neutrophil cell counting increase, or normal.4. ultrasonic examination, ultrasound diagnosis are one-sided or the bilateral adnexa increases slightly.
3, criterion of therapeutical effect:
Produce effects: clinical symptoms and sign disappear, and the chemical examination hemogram is normal, and scorching change of B ultrasonic disappears.
Effectively: clinical symptoms and Signs alleviate, and the chemical examination hemogram descends, and scorching the change alleviates B ultrasonic.
Invalid: clinical symptoms and sign no change, the scorching no change that becomes of chemical examination hemogram and ultrasound diagnosis.
Worsen: sings and symptoms increases the weight of or increases, and the chemical examination hemogram raises, and B ultrasonic increases the weight of by scorching the change.
4, efficacy result
In a word, adopt quick-acting adnexaes to loose and treat chronic adnexitis 2000 examples.
Observation of curative effect after treating
95%5-7 days take effect, recovery from illness in 85%1-2 month, recovery from illness in 10%3 months, 5% weak curative effect.
Come further to set forth the preparation method of medicine of the present invention by the following examples
Embodiment
1: the preparation that the quick-acting adnexaes of medicine of the present invention loose: Fructus Foeniculi (do and fry) 10 grams, Radix Linderae 10 grams, Radix et Bulbus Allii tuberosi 10 grams, Rhizoma Cyperi (vinegar system) 10 grams, Semen Vaccariae 20 grams, Fructus Liquidambaris 10 grams, Flos Carthami 10 grams, Radix Angelicae Sinensis 30 grams (processed with wine), Ramulus Cinnamomi 10 grams.To pulverize behind each medicine mix homogeneously, foam 30 grams of getting it filled add water, and each amount of water did not have powder 3cm to be advisable, and 20 milliliters of decocting 20-30 minute rear filtrates can be taken.
2: will pulverize behind each the medicine mix homogeneously in [1], also can be with each 10 grams of medicine foam, 3 times on the one direct warm boiled waters.
3: soaking agent: will pulverize behind each the medicine mix homogeneously in the above prescription,, directly soak 60 minutes postprecipitations and soak clothes with boiled water with each 10 grams of medicine foam one 20 grams.1-2 time on the one.
Claims (3)
1. a medicine for the treatment of chronic adnexitis is characterized in that it mainly is to be made by following bulk drugs: Fructus Foeniculi (do and fry), Radix Linderae, Radix et Bulbus Allii tuberosi, Rhizoma Cyperi (vinegar system), Semen Vaccariae, Fructus Liquidambaris, Flos Carthami, Radix Angelicae Sinensis (processed with wine), Ramulus Cinnamomi composition.
2. according to the medicine of claim 1, wherein the consumption of a raw material is Fructus Foeniculi (do and fry) 10 grams, Radix Linderae 10 grams, Radix et Bulbus Allii tuberosi 10 grams, Rhizoma Cyperi (vinegar system) 10 grams, Semen Vaccariae 20 grams, Fructus Liquidambaris 10 grams, Flos Carthami 10 grams, Radix Angelicae Sinensis 30 grams (processed with wine), Ramulus Cinnamomi 10 grams.
3. the preparation method of claim 1 or 2 described medicines, it comprises the following steps:
A), weighting raw materials: Fructus Foeniculi (do fry), Radix Linderae, Radix et Bulbus Allii tuberosi, Rhizoma Cyperi (vinegar system), Semen Vaccariae, Fructus Liquidambaris, Flos Carthami, Radix Angelicae Sinensis (processed with wine), Ramulus Cinnamomi is standby.
B), with the Fructus Foeniculi of described dosage ratio (do and fry), Radix Linderae, Radix et Bulbus Allii tuberosi, Rhizoma Cyperi (vinegar system), Semen Vaccariae, Fructus Liquidambaris, Flos Carthami, Radix Angelicae Sinensis (processed with wine), Ramulus Cinnamomi is formed.To pulverize behind each medicine mix homogeneously, foam 30 grams of getting it filled add water, and each amount of water did not have powder 3cm to be advisable, and 20 milliliters of decocting 20-30 minute filtrates can be taken.Also can be with each 10 grams of medicine foam, 3 times on the one direct warm boiled waters.Medicine of the present invention.
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| CNB2004100706459A CN100475251C (en) | 2004-07-28 | 2004-07-28 | Medication for treating chronic appendages inflammation, and preparation method thereof |
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| CNB2004100706459A CN100475251C (en) | 2004-07-28 | 2004-07-28 | Medication for treating chronic appendages inflammation, and preparation method thereof |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102600399A (en) * | 2012-03-29 | 2012-07-25 | 常熟市常福有机复合肥有限公司 | Traditional Chinese medicine for treating chronic annex inflammatory mass and preparation method of traditional Chinese medicine |
| CN104352953A (en) * | 2014-10-11 | 2015-02-18 | 胥琴 | Traditional Chinese medicine composition for treating chronic annexitis |
| WO2021057988A1 (en) * | 2019-09-27 | 2021-04-01 | 廖睿 | Use of reagent for detecting content of faecal calprotectin in preparation of kit for screening fallopian tube lesions |
-
2004
- 2004-07-28 CN CNB2004100706459A patent/CN100475251C/en not_active Expired - Fee Related
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102600399A (en) * | 2012-03-29 | 2012-07-25 | 常熟市常福有机复合肥有限公司 | Traditional Chinese medicine for treating chronic annex inflammatory mass and preparation method of traditional Chinese medicine |
| CN104352953A (en) * | 2014-10-11 | 2015-02-18 | 胥琴 | Traditional Chinese medicine composition for treating chronic annexitis |
| CN104352953B (en) * | 2014-10-11 | 2016-02-10 | 胥琴 | A kind of Chinese medicine composition for the treatment of chronic adnexitis |
| WO2021057988A1 (en) * | 2019-09-27 | 2021-04-01 | 廖睿 | Use of reagent for detecting content of faecal calprotectin in preparation of kit for screening fallopian tube lesions |
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| Publication number | Publication date |
|---|---|
| CN100475251C (en) | 2009-04-08 |
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