CN113730165A

CN113730165A - Device for detecting lymphatic reflux of multiple parts of body surface

Info

Publication number: CN113730165A
Application number: CN202111162951.5A
Authority: CN
Inventors: 韩涛
Original assignee: Nanjing Childrens Hospital of Nanjing Medical University
Current assignee: Nanjing Childrens Hospital of Nanjing Medical University
Priority date: 2021-09-30
Filing date: 2021-09-30
Publication date: 2021-12-03

Abstract

The invention provides a device for detecting lymphatic return of a plurality of parts on the body surface, and relates to the technical field of lymph. The device comprises a control unit, an injection mechanism, a pressing mechanism, an operating platform and a developing mechanism, wherein the injection mechanism, the pressing mechanism and the developing mechanism are all arranged on the operating platform, a plurality of injection stations are arranged on the operating platform, any injection station corresponds to the injection mechanism, the injection mechanism is connected with the control unit and is used for injecting contrast medium to an injection part, the pressing mechanism is connected with the control unit and is used for pressing the injection part, the developing mechanism is connected with the control unit, and the developing mechanism is used for developing; the device can effectively develop the lymphatic return position to provide convenience for the diagnosis of lymphatic vessel diseases, and the operation is completed through automatic control, thereby providing convenience for medical staff.

Description

Device for detecting lymphatic reflux of multiple parts of body surface

Technical Field

The invention relates to the technical field of lymph, in particular to a device for detecting lymph reflux of a plurality of parts on a body surface.

Background

Cystic lymphangioma, which is known as lymphangioma, is a common congenital vascular malformation for infants, occurs in about 75% of head and neck, and is accompanied with local symptoms after birth, and the pathogenesis of the cystic lymphangioma is considered to be local lymphatic drainage obstacle in many aspects at present, so that lymphatic fluid retention is caused, and lymphatic vessels are expanded to form cystic masses. According to different structures of LM histology, the formed cystic masses are divided into three types, namely macrocystic type, microcystic type and mixed cystoid type. Clinically, lymph fluid can accumulate again after surgery at the specific site cLM, resulting in recurrence of the lesion. This suggests that we cLM are not isolated foci and may be associated with the normal lymphatic return system of the human body. Therefore, exploring cLM the relationship between lymphatic system helps to understand the origin of its focus and the pathophysiological changes.

Current imaging examinations, including ultrasound, MR, and CT, focus on studying and displaying cLM the condition of the cystic cavity itself or the lymph within the sac, which are of great value for locating, characterizing, and determining tissue type of lesions. However, these examination devices fail to show the surrounding lymphatic vessels, and there is no judgment about their relationship to the lymphatic system, so that a lymphatic imaging examination is required to perfect the diagnosis of cLM. It is worth noting that there are few centers currently in the world that explore cLM relationships to the normal lymphatic system, and cLM lymphatic fluid inflow and outflow tracts.

However, no report of the application of lymphography in the diagnosis and treatment of lymphatic diseases is available at home at present.

Disclosure of Invention

The invention aims to provide a device for detecting lymphatic return at a plurality of parts on the body surface, which can contrast lymphatic vessels by injecting contrast medium so as to provide convenience for diagnosing lymphatic vessel diseases and provide convenience for medical staff by completing operation through automatic control.

The embodiment of the invention is realized by the following steps:

the embodiment of the application provides a device for detecting a plurality of position lymph of body surface backward flow, it includes the control unit, injection mechanism, pressing mechanism, operation platform and video picture mechanism, injection mechanism, pressing mechanism and video picture mechanism all set up on operation platform, the last a plurality of injection stations that are provided with of operation platform, injection mechanism can freely move on operation platform, arbitrary injection station is corresponding with injection mechanism, injection mechanism is connected with the control unit, injection mechanism is used for injecting the contrast medium to the injection position, pressing mechanism is connected with the control unit, pressing mechanism is used for pressing the injection position, video picture mechanism is connected with the control unit, video picture mechanism is used for developing.

In some embodiments of the present invention, the operation platform is a fixed seat, the fixed seat includes a foot rest, an armrest and a backrest, the foot rest, the armrest and the backrest are all provided with an injection station, and the foot rest, the armrest and the backrest are all provided with a fixing assembly, and the fixing assembly is used for fixing limbs, the head and the body on the seat.

In some embodiments of the present invention, any of the fixing assemblies includes a belt, the belt is wound around two sides of the injection station, and the belt is used for fixing the injection site.

In some embodiments of the invention, the injection mechanism comprises a first gimbal arm disposed on the stationary seat and an injection assembly disposed at a free end of the first gimbal arm.

In some embodiments of the present invention, the injection assembly includes an injection cylinder, the injection cylinder is connected to the first universal arm, a push rod is movably disposed in the injection cylinder, the push rod is connected to a motor, the motor is connected to a control unit, and the control unit is configured to control a rotation number of the motor.

In some embodiments of the present invention, the pressing mechanism includes a second universal arm and a massage component, the second universal arm is disposed on the fixed seat, the second universal arm is connected with the control unit, and the massage component is disposed on the second universal arm.

In some embodiments of the present invention, the massage assembly includes a massage plate, a massage belt is disposed on the massage plate, the massage belt is connected to the control unit, and the control unit is configured to control the on/off and the vibration frequency of the massage belt.

In some embodiments of the present invention, the fixed seat is further provided with a positioning mechanism, the positioning mechanism is used for positioning an injection site, and the positioning mechanism is respectively matched with the pressing mechanism and the injection mechanism.

In some embodiments of the present invention, the imaging mechanism includes a display, the display is disposed on the fixed seat, and the display is connected with a near-infrared probe, and the near-infrared probe is used for exciting the contrast agent to image.

In some embodiments of the present invention, the near infrared probe is connected to a control unit, and the control unit is configured to count the number of lymphatic vessels and feed the count back to the display.

Compared with the prior art, the embodiment of the invention has at least the following advantages or beneficial effects:

the embodiment of the invention provides a device for detecting lymphatic return at multiple parts of a body surface, which can inject contrast agents at multiple parts of a human body through arranging multiple injection stations and a freely-moving injection mechanism, and can lead lymphatic fluid to return through a pressing mechanism, so that the development condition of the contrast agents in lymphatic vessels can be displayed on a developing mechanism, thereby facilitating medical staff to observe the parameters such as the form, contraction frequency, quantity and the like of the lymphatic vessels, and providing convenience for the detection of diseases at the lymphatic parts; and the whole device realizes semi-automatic control through the control of the control unit, thereby greatly reducing the operation complexity of medical personnel.

During the in-service use, place the human body in on operation platform, confirm the position that needs the injection by medical personnel, afterwards control injection mechanism by the control unit and inject the contrast medium to the injection position, the rethread presses the mechanism and presses the injection position to make lymph liquid backward flow, thereby it makes the contrast medium succeed in the radiography to drive the contrast medium inflow lymphatic vessel, later adopts the development mechanism to detect and develop the lymphatic vessel, so that the lymphatic vessel after the radiography forms images in development mechanism, again by medical personnel observation.

Drawings

In order to more clearly illustrate the technical solutions of the embodiments of the present invention, the drawings needed to be used in the embodiments will be briefly described below, it should be understood that the following drawings only illustrate some embodiments of the present invention and therefore should not be considered as limiting the scope, and for those skilled in the art, other related drawings can be obtained according to the drawings without inventive efforts.

FIG. 1 is a schematic structural diagram of an apparatus for detecting lymphatic return at multiple locations on a body surface according to an embodiment of the present invention;

FIG. 2 is a schematic view of the injection assembly in an embodiment of the present invention;

fig. 3 is a schematic structural diagram of a pressing assembly according to an embodiment of the present invention.

Icon: 1. fixing a seat; 101. a handrail; 102. a backrest; 103. a belt; 104. a foot rest; 2. a control unit; 3. an injection mechanism; 301. a first gimbal arm; 302. an injection tube; 303. a push rod; 304. a motor; 4. a pressing mechanism; 401. a second gimbal arm; 402. a massage plate; 403. a massage belt; 5. a developing mechanism; 501. a display; 502. a near-infrared probe; 6. a positioning mechanism.

Detailed Description

In order to make the objects, technical solutions and advantages of the embodiments of the present invention clearer, the technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are some, but not all, embodiments of the present invention. The components of embodiments of the present invention generally described and illustrated in the figures herein may be arranged and designed in a wide variety of different configurations.

Thus, the following detailed description of the embodiments of the present invention, presented in the figures, is not intended to limit the scope of the invention, as claimed, but is merely representative of selected embodiments of the invention. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.

It should be noted that: like reference numbers and letters refer to like items in the following figures, and thus, once an item is defined in one figure, it need not be further defined and explained in subsequent figures.

In the description of the embodiments of the present invention, it should be noted that, if the terms "center", "upper", "lower", "left", "right", "vertical", "horizontal", "inner", "outer", etc. indicate orientations or positional relationships based on the orientations or positional relationships shown in the drawings or the orientations or positional relationships that the products of the present invention are usually placed in when used, the orientations or positional relationships are only used for convenience of describing the present invention and simplifying the description, but the terms do not indicate or imply that the devices or elements indicated must have specific orientations, be constructed in specific orientations, and operate, and therefore, should not be construed as limiting the present invention. Furthermore, the terms "first," "second," "third," and the like are used solely to distinguish one from another and are not to be construed as indicating or implying relative importance.

Furthermore, the terms "horizontal", "vertical", "overhang" and the like do not require that the components be absolutely horizontal or overhang, but may be slightly inclined. For example, "horizontal" merely means that the direction is more horizontal than "vertical" and does not mean that the structure must be perfectly horizontal, but may be slightly inclined.

In the description of the embodiments of the present invention, "a plurality" represents at least 2.

In the description of the embodiments of the present invention, it should be further noted that unless otherwise explicitly stated or limited, the terms "disposed," "mounted," "connected," and "connected" should be interpreted broadly, and may be, for example, fixedly connected, detachably connected, or integrally connected; can be mechanically or electrically connected; they may be connected directly or indirectly through intervening media, or they may be interconnected between two elements. The specific meanings of the above terms in the present invention can be understood by those skilled in the art according to specific situations.

Examples

Referring to fig. 1, fig. 1 is a schematic structural diagram of an apparatus for detecting lymphatic return at multiple locations on a body surface according to an embodiment of the present invention.

The embodiment of the application provides a device for detecting a plurality of position lymph of body surface backward flow, it includes the control unit 2, injection mechanism 3, pressing mechanism 4, operation platform and video display mechanism 5, injection mechanism 3, pressing mechanism 4 and video display mechanism 5 all set up on operation platform, the last a plurality of injection stations that are provided with of operation platform, injection mechanism 3 can freely move on operation platform, arbitrary injection station is corresponding with injection mechanism 3, injection mechanism 3 is connected with the control unit 2, injection mechanism 3 is used for injecting the contrast medium to the injection position, pressing mechanism 4 is connected with the control unit 2, pressing mechanism 4 is used for pressing the injection position, video display mechanism 5 is connected with the control unit 2, video display mechanism 5 is used for developing. The system can inject contrast agents at a plurality of parts of a human body by arranging a plurality of injection stations and an injection mechanism 3 which can move freely, and enables lymph liquid to flow back by a pressing mechanism 4, so that the development condition of the contrast agents in lymph vessels can be displayed on a display mechanism 5, thereby facilitating medical workers to observe parameters such as the form, contraction frequency and quantity of the lymph vessels and providing convenience for the detection of diseases at the lymph parts; and the whole device realizes semi-automatic control through the control of the control unit 2, thereby greatly reducing the operation complexity of medical personnel. During the in-service use, place the human body in on operation platform, confirm the position that needs the injection by medical personnel, later control injection mechanism 3 by control unit 2 and inject the contrast medium to the injection position, rethread pressing means 4 presses the injection position, so that lymph fluid backward flow, thereby it makes the contrast medium succeed in the radiography to drive the contrast medium inflow lymphatic vessel, later adopt development mechanism 5 to detect and develop the lymphatic vessel, so that the lymphatic vessel imaging after the radiography is on development mechanism 5, observe by medical personnel again.

In this embodiment, the pressing mechanism 4 presses from far to near during the pressing process, and repeatedly presses 3 to 4 times to make the lymph fluid fully flow back, thereby facilitating the lymph fluid to completely drive the contrast agent to flow into the lymph vessel to realize clear and complete contrast. Alternatively, the pressing may be performed by other pressing methods as long as the lymph is allowed to flow back successfully.

In the embodiment, the contrast agent is indocyanine green, which is a near-infrared fluorescent contrast agent with high safety, after being excited by 750-810nm laser, ICG can emit infrared light to penetrate through a tissue with a thickness of about 1cm, and the infrared light is captured by an infrared camera to form a dynamic image, and due to the good penetrating power and low toxicity in biological tissues, the contrast agent is gradually applied to diagnosis and treatment of primary or secondary lymphedema in recent years, and scientific basis is provided for reconstruction of lymphatic circulation disorder, change of lymphatic structure function and lymphatic return.

The operation platform is a fixed seat 1, the fixed seat 1 comprises a foot rest 104, armrests 101 and a backrest 102, injection stations are arranged on the foot rest 104, the armrests 101 and the backrest 102, and fixing components are arranged on the foot rest 104, the armrests 101 and the backrest 102 and used for fixing limbs, the head and the body on the seat.

Any one of the fixing assemblies comprises a belt 103, the belt 103 is wound on two sides of the injection station, and the belt 103 is used for fixing the injection site. The injection site of the patient is secured by a band 103 to avoid shifting the injection site of the patient during the injection process, which in turn causes the injection site to shift.

In this embodiment, fixed subassembly still includes receiver and mounting, and receiver and mounting set up on the seat, and in the band 103 was around locating the receiver, the band 103 can freely contract in the receiver, and the mounting is used for the card to establish band 103 to accomplish the fixed of band 103, pull out the band 103 that is located the receiver when using, pass through the mounting joint with the other end of band 103, receiver and mounting set up respectively in the both sides of injecting the station. In addition, other structures such as magic tapes respectively arranged on the injection station and the strap 103 can be used to stretch and fix the strap 103.

The injection mechanism 3 comprises a first universal arm 301 arranged on the fixed seat 1, the first universal arm 301 is connected with the control unit 2, and an injection assembly arranged at the free end of the first universal arm 301. Wherein the first universal arm 301 can rotate freely on the stationary seat 1 so that the injection assembly can inject different parts of the human body.

The injection assembly comprises an injection tube 302, the injection tube 302 is connected with a first universal arm 301, a push rod 303 is movably arranged in the injection tube 302, the push rod 303 is connected with a motor 304, the motor 304 is connected with a control unit 2, and the control unit 2 is used for controlling the revolution number of the motor 304. The control unit 2 controls the number of revolutions of the motor 304 so that the motor 304 drives the push rod 303 to push forward according to the amount of contrast liquid required to be injected, so as to ensure that the injected amount of contrast liquid is accurate enough to avoid contrast failure caused by too much or too little injected contrast liquid.

The pressing mechanism 4 includes a second universal arm 401 and a massage component, the second universal arm 401 is disposed on the stationary seat 1, the second universal arm 401 is connected to the control unit 2, and the massage component is disposed on the second universal arm 401. Freely rotate on the fixed seat 1 through the second universal arm 401 to massage different injection parts, so that the lymph liquid flows back, the lymph liquid drives the contrast agent to flow back, and the lymph vessel is subjected to radiography.

The massage component comprises a massage plate 402, a massage belt 403 is arranged on the massage plate 402, the massage belt 403 is connected with a control unit 2, and the control unit 2 is used for controlling the on-off and vibration frequency of the massage belt 403. The vibration frequency of the massage belt 403 is controlled by the control unit 2 to ensure that the massage belt 403 can perform massage from far to near, thereby causing the lymph to flow back.

In this embodiment, the massage time is about 4-5min to avoid that lymph fluid cannot flow back sufficiently due to too short massage time, and then the contrast is not obvious, or lymph fluid flows back too much due to too long massage time, and then lymph vessels are damaged.

The fixed seat 1 is also provided with a positioning mechanism 6, the positioning mechanism 6 is used for positioning an injection part, and the positioning mechanism 6 is respectively matched with the pressing mechanism 4 and the injection mechanism 3. The injection site is positioned by the positioning mechanism 6 so that the injection mechanism 3 and the pressing mechanism 4 can be accurately aligned with the injection site.

In this embodiment, all be provided with infrared sensor on pressing mechanism 4 and the injection mechanism 3, positioning mechanism 6 can send infrared radiation on the injection site, comes to adjust positioning mechanism 6 through medical personnel to the injection site is aimed at to the infrared ray, and the infrared sensor on pressing mechanism 4 and the injection mechanism 3 can match with the infrared ray of emission on positioning mechanism 6, thereby realizes accurate injection and pressing. Alternatively, a camera may be provided on the positioning mechanism 6 and the image may be transmitted to the control unit 2 to identify the injection site, and the control unit 2 controls the injection mechanism 3 and the pressing mechanism 4 to inject and press the injection site.

The imaging mechanism 5 includes a display 501, the display 501 is disposed on the stationary seat 1, the display 501 is connected with a near-infrared probe 502, and the near-infrared probe 502 is used for exciting the contrast agent to image. Infrared rays are emitted through the near-infrared probe 502 to activate the contrast fluid, so that a lymphatic vessel image after contrast with the contrast fluid is displayed on the display 501.

The near-infrared probe 502 is connected to the control unit 2, and the control unit 2 is configured to count the number of lymphatic vessels and feed back the count to the display 501. The contrast region sensed by the near-infrared probe 502 can be identified by the control unit 2 to identify the number of lymphatic vessels.

In summary, embodiments of the present invention provide an apparatus for detecting lymphatic return at multiple locations on a body surface, which can inject contrast media at multiple locations on a human body by providing multiple injection stations and a freely movable injection mechanism 3, and can return lymph fluid by a pressing mechanism 4, so that the contrast media can be displayed on a visualization mechanism 5, thereby facilitating medical staff to observe parameters such as the form, contraction frequency and number of lymph vessels, and facilitating the detection of diseases at lymph locations; and the whole device realizes semi-automatic control through the control of the control unit 2, thereby greatly reducing the operation complexity of medical personnel. During the in-service use, place the human body in on operation platform, confirm the position that needs the injection by medical personnel, later control injection mechanism 3 by control unit 2 and inject the contrast medium to the injection position, rethread pressing means 4 presses the injection position, so that lymph fluid backward flow, thereby it makes the contrast medium succeed in the radiography to drive the contrast medium inflow lymphatic vessel, later adopt development mechanism 5 to detect and develop the lymphatic vessel, so that the lymphatic vessel imaging after the radiography is on development mechanism 5, observe by medical personnel again.

In the embodiment of the invention, the normal skin at the far end of the focus is taken as an injection point and ICG injection in the skin and subcutaneous is carried out at multiple points according to the judgment of medical staff, the injection amount of each point is about 0.05ml, and the total amount is not more than 0.5 mg/kg. The injection sites at specific sites are summarized as follows: (1) neck and face parts: taking a hair line leveling area of the temporal scalp on the same side, and an area before and after the ear; (2) chest: the area around the ipsilateral areola; (3) abdomen and waist back: injecting at multiple points along the midline with the distance of the focus of 3-5 cm; (4) upper limb: the first and second webs, the palm side of the wrist and the palm side of the elbow of the affected limb; (5) lower limb: the first and second toe webs, the lateral condylar inferior of the ankle, and the popliteal fossa of the affected limb; (6) finger or toe: two sides of the tip of the finger (toe) and under the nail bed; (7) tongue portion: the tongue tip.

The lymphatic vessel development is promoted by the local massage of the pressing mechanism 4: after being injected with indocyanine green, all parts are massaged from far end to near end for about 10min, and four limbs can be repeatedly pressed from far to near by using tourniquets for 3-4 times to promote lymphatic fluid backflow.

ICG fluorescence imaging: the display 501 (Mingde pharmaceutical biotechnology, Inc.) is adopted, the hand-held near infrared probe 502 is perpendicular to the skin, the extracorporeal irradiation is kept at a distance of 10cm, the subcutaneous ICG imaging can be excited, and the data is recorded in real time in a dynamic video mode.

Lymphography data: the visualization of the lymphatic vessels is observed, the number, the form and the contraction frequency of the input lymphatic vessels are recorded by the control unit 2, and the observation duration is about 10 min. In the massage process, people pay attention to timely wiping the skin with alcohol gauze, and the phenomenon that the contrast medium is remained on the skin to form artifacts is avoided.

The above is only a preferred embodiment of the present invention, and is not intended to limit the present invention, and various modifications and changes will occur to those skilled in the art. Any modification, equivalent replacement, or improvement made within the spirit and principle of the present invention should be included in the protection scope of the present invention.

Claims

1. The utility model provides a device for detecting a plurality of positions lymph of body surface backward flow, a serial communication port, including the control unit, inject mechanism, pressing means, operation platform and video picture mechanism, inject mechanism, pressing means and video picture mechanism all set up in operation platform is last, operation platform is last to be provided with a plurality of injection stations, injection mechanism can freely remove on the operation platform, arbitrary injection station with injection mechanism is corresponding, injection mechanism with the control unit is connected, injection mechanism is used for injecting the contrast medium to injection position, pressing means with the control unit is connected, pressing means is used for right injection position presses, video picture mechanism with the control unit is connected, video picture mechanism is used for developing.

2. The apparatus of claim 1, wherein the operation platform is a fixed seat comprising a foot rest, an armrest and a backrest, the injection station is disposed on the foot rest, the armrest and the backrest, and a fixing assembly is disposed on the foot rest, the armrest and the backrest, and the fixing assembly is used for fixing limbs, the head and the body on the seat.

3. The apparatus of claim 2, wherein each of the plurality of securing assemblies comprises a strap that is wrapped around the injection site, the strap being configured to secure the injection site.

4. The apparatus of claim 2, wherein the injection mechanism comprises a first gimbal arm disposed on the stationary seat, the first gimbal arm coupled to the control unit, and an injection assembly disposed at a free end of the first gimbal arm.

5. The device for detecting lymphatic return at multiple parts of a body surface according to claim 4, characterized in that the injection assembly comprises an injection tube, the injection tube is connected with the first universal arm, a push rod is movably arranged in the injection tube, the push rod is connected with a motor, the motor is connected with the control unit, and the control unit is used for controlling the number of revolutions of the motor.

6. The apparatus of claim 4, wherein the pressing mechanism comprises a second universal arm disposed on the stationary seat and a massage assembly coupled to the control unit, the massage assembly being disposed on the second universal arm.

7. The apparatus of claim 6, wherein the massage assembly comprises a massage plate, the massage plate is provided with a massage belt, the massage belt is connected to the control unit, and the control unit is configured to control the opening and closing of the massage belt and the vibration frequency.

8. The apparatus of claim 6, wherein the fixed seat is further provided with a positioning mechanism for positioning the injection site, and the positioning mechanism is respectively matched with the pressing mechanism and the injection mechanism.

9. The apparatus of claim 2, wherein the imaging mechanism comprises a display, the display is disposed on the stationary seat, and the display is connected to a near-infrared probe for exciting the contrast agent to image.

10. The apparatus of claim 9, wherein the near infrared probe is connected to the control unit, and the control unit is configured to count the number of lymphatic vessels and feed the count back to the display.