CN111990641A - Alcohol-dispelling liver-protecting tablet and construction method thereof - Google Patents

Abstract

The invention relates to an anti-alcohol liver-protecting tablet which comprises the following components in percentage by mass: 10-22% of hawthorn, 3-7% of radix puerariae, 8.5-17% of corn oligopeptide powder, 6.3-12.3% of oyster peptide, 2.5-5.8% of xylo-oligosaccharide, 1.3-2.7% of vitamin C, 1.1-3.5% of L-leucine, 0.3-1.4% of L-glutamic acid, 0.05-0.15% of L-cysteine, 0.11-1.4% of glycine, 0.8-3.5% of citric acid, 1.5-3.5% of L-malic acid, 0.3-1.8% of taurine and the balance of lactose. The preparation method comprises the five steps of preparing extract powder, mixing materials, preparing solution, granulating, coating and the like. The invention has wide raw material sources, low cost and small toxic and side effects, can fully exert the efficacy of each component, and greatly improve the capabilities of relieving alcoholism, sobering up and nourishing human bodies.

Description

Alcohol-dispelling liver-protecting tablet and construction method thereof

Technical Field

The invention relates to an anti-alcohol liver-protecting tablet and a construction method thereof, belonging to the technical field of health-care food.

Background

The anti-alcohol tablet, the anti-alcohol agent and other products on the market are used in huge quantities, but the anti-alcohol principle of the anti-alcohol tablet, the anti-alcohol agent and other products is usually two types of alcohol absorption inhibiting type and dry metabolism promoting type, wherein after the anti-alcohol product for inhibiting alcohol absorption is taken, the function of a human digestive system is usually inhibited, so that the alcohol absorption capacity of the human body is reduced, the functional disorder of the human digestive system can be caused, great discomfort can be caused to the human body, and meanwhile, the effective auxiliary treatment capacity is lacked for alcohol entering human blood and entering liver along with the blood, so that the adverse effect time of the alcohol on the human body is longer while the alcohol decomposition burden of the human liver is increased; the traditional Chinese medicine components such as the kudzu root and the hawthorn lamp act on the liver, the stomach, the kidney and other systems of the human body to improve the decomposition capacity and the whole metabolism level of the human body to alcohol, and accelerate the reduction of the alcohol concentration in the blood of the human body and the reduction of the alcohol content in the human body.

Meanwhile, various anti-alcohol products used at present often directly participate in anti-alcohol and sober-up physiological activities after being eaten, but due to serious differences of physiological levels of digestive system and liver functions of users, especially when the anti-alcohol products are used by people with poor digestive system capability, low liver function and the like, the performance of the effectiveness of the current anti-alcohol products is seriously influenced, and meanwhile, the anti-alcohol products increase the digestive burden of human bodies and the liver detoxification burden due to the fact that the anti-alcohol products are not fully and slowly exerted, and further harm is caused to the human bodies.

Therefore, although various existing anti-inebriation products can achieve the aim of anti-inebriation to a certain extent, the existing anti-inebriation products have poor stability of anti-inebriation effect to different extents, and can cause adverse effects on organs of human bodies such as intestines, stomachs and livers to different extents.

Therefore, in view of the current situation, a brand-new anti-hangover product and a preparation process thereof are urgently needed to meet the needs of practical use.

Disclosure of Invention

The invention aims to overcome the defects and provides an anti-alcohol liver-protecting tablet and a preparation method thereof.

In order to realize the purpose, the invention is realized by the following technical scheme:

an anti-alcohol liver-protecting tablet comprises the following substances in percentage by mass: 10-22% of hawthorn, 3-7% of radix puerariae, 8.5-17% of corn oligopeptide powder, 6.3-12.3% of oyster peptide, 2.5-5.8% of xylo-oligosaccharide, 1.3-2.7% of vitamin C, 1.1-3.5% of L-leucine, 0.3-1.4% of L-glutamic acid, 0.05-0.15% of L-cysteine, 0.11-1.4% of glycine, 0.8-3.5% of citric acid, 1.5-3.5% of L-malic acid, 0.3-1.8% of taurine, 0.01-0.21% of aspartame (containing phenylalanine), 0.3-0.35% of acesulfame potassium, 1.3-2.7% of magnesium stearate, 0.1-0.4% of lycopene, 0.3-1.1% of curcumin and the balance of lactose.

A preparation method of an anti-alcohol liver-protecting tablet comprises the following steps:

s1, preparing extract powder, adding deionized water into the hawthorn and the kudzuvine root, decocting twice at a constant temperature of 90-110 ℃, wherein the decocting time is 1-2 hours each time, filtering and collecting decoction after the first decoction is finished, naturally cooling the decoction, the residual hawthorn and the kudzuvine root to normal temperature, then adding deionized water into the residual hawthorn and the kudzuvine root for secondary decoction, filtering the secondary decoction after the decoction is finished, and mixing the filtered decoction with the first decoction; then filtering the mixed decoction, collecting the filtrate in a centralized manner, heating and concentrating the filtrate at the constant temperature of 60-80 ℃ to obtain thick paste with the relative density of 1.35-1.38 after the filtrate is collected, finally drying the thick paste in vacuum, and crushing the dried solid material to obtain extract powder of 80-500 meshes;

s2, mixing the materials, adding the extract powder obtained in the step S1, lactose, citric acid, L-malic acid and oyster peptide into a mixing device, mixing at the constant temperature of 20-40 ℃, adding vitamin C, aspartame, acesulfame potassium and taurine into a mixing machine for continuously mixing for 10-30 minutes after mixing for 1-3 minutes, and then intensively storing the mixed solid materials in the mixing machine for later use;

s3, preparing a solution, after the step S2 is completed, adding the lycopene into 1-4 kg of deionized water and uniformly mixing for later use, and simultaneously adding the curcumin into 1-4 kg of deionized water and uniformly mixing for later use;

s4, granulating, wherein after the step S3 is completed, a lycopene water solution is added into a mixer and mixed with solid materials in the mixer, the mixture is stirred and mixed for 5-15 minutes through the mixer, the mixture is filtered through a 12-20-mesh screen, the filtered mixed materials are added into the mixer again, a curcumin water solution is added into the mixer and mixed and stirred for 2-10 minutes, finally the mixture is transferred into a granulator and granulated through a 12-20-mesh screen, the prepared semi-finished granules are dried for 1-2 hours at 50-60 ℃ in a hot air circulation oven, and finally, the granules are granulated through a 14-20-mesh screen to obtain finished product particles for dispelling effects of alcohol;

and S5, coating, namely conveying the finished product of the hangover alleviating granules obtained in the step S4 into coating equipment, and coating a coating layer with the thickness of 1-5 mm on the outer surface of the hangover alleviating granules to obtain the finished product of the hangover alleviating and liver protecting tablet.

Further, the residual hawthorn and kudzu vine root residues and the filtered filter residues after the processing treatment in the step S1 are gathered, then yeast accounting for 1% -10% of the total amount of the residues and the filter residues is added into the residues and the filter residues and uniformly mixed, then the mixture is pressed into a filter cake with a block structure, the thickness of the filter cake is 3-10 cm, the length and the width of the filter cake are not more than 30 cm, and the water content of the filter cake is not more than 4%.

Furthermore, the total amount of the deionized water in the step S1 is 2.5-5 times of the total amount of the hawthorn and the kudzuvine root.

Further, in the step S5, the coating layer includes an auxiliary layer and a functional layer from the inside to the outside, wherein the thickness of the functional layer is 10% to 30% of the thickness of the auxiliary layer.

Further, the auxiliary layer is composed of the following substances in percentage by mass: 10-15% of schisandra chinensis powder, 3-7% of salvia miltiorrhiza powder, 3.5-7% of liquorice powder, 2.3-5.3% of gardenia powder, 11-21% of yam powder, 5.3-11.7% of cassia seed powder and the balance of refined honey.

Furthermore, the schisandra chinensis powder, the salvia miltiorrhiza powder, the liquorice powder, the gardenia powder, the yam powder and the cassia seed powder are all 20-100 meshes, and the schisandra chinensis powder, the salvia miltiorrhiza powder, the liquorice powder, the gardenia powder, the yam powder and the cassia seed powder are all freeze-dried powders.

Further, the functional layer is composed of the following substances in percentage by mass: 10-15% of L-arabinose, 5-11% of maltitol, 3.5-7.1% of carboxymethyl cellulose, 2.3-5.3% of sulfur-containing amino acid, 2.5-4.1% of inositol, 8.6-14.5% of glucose, 1-2.5% of acetic acid bacteria freeze-dried powder and the balance of milk powder.

A construction method of an anti-alcohol liver-protecting tablet comprises the following steps of:

firstly, mixing materials for preparation, namely heating refined honey to a molten state, adding schisandra chinensis powder, salvia miltiorrhiza powder, liquorice powder, gardenia powder, yam powder and semen cassiae powder into the refined honey, and uniformly stirring to obtain a liquid auxiliary layer for later use; simultaneously stirring and mixing L-arabinose, maltitol, carboxymethyl cellulose, sulfur-containing amino acid, inositol, glucose, acetic acid bacteria freeze-dried bacteria powder and milk powder at the constant temperature of 20-40 ℃ to obtain a powdery functional layer for later use;

secondly, primary coating, namely directly coating the liquid auxiliary layer prepared in the first step on the outer layer of the finished product hangover alleviating granule prepared in the step S4, granulating again, and carrying out air drying operation by cold wind at-5 ℃ to obtain a semi-finished product hangover alleviating and liver protecting tablet;

and thirdly, press-molding, namely mixing the semi-finished product of the alcohol-relieving and liver-protecting tablet prepared in the second step with the powdery functional layer prepared in the first step, so that the powdery functional layer is coated outside the semi-finished product of the alcohol-relieving and liver-protecting tablet, and press-molding the mixture by a tablet press to obtain the finished product of the alcohol-relieving and liver-protecting tablet.

The invention has wide raw material sources, low cost and small toxic and side effects, can fully exert the efficacies of each component, greatly improve the capabilities of relieving alcoholism, sobering up and nourishing human bodies, and simultaneously can effectively reduce the absorption efficiency and the absorption amount of the human bodies to alcohol, effectively improve the metabolism level of the human bodies and accelerate the decomposition capability of the human bodies to the alcohol and the excretion capability of the alcohol from the human bodies on the one hand, thereby achieving the purposes of quickly relieving alcoholism and sobering up and reducing the adverse effects of the alcohol on the digestive system and the nervous system of the human bodies; on the other hand, the alcohol-containing liver-protecting health-care wine can effectively reduce the damage of alcohol to the liver, prevent fat from accumulating at the liver part, effectively improve the regeneration capacity of stem cells, recover and improve the comprehensive physiological function of the liver, promote bile secretion, further improve the digestive capacity of a human body, eliminate the burden and adverse effect of alcohol on the digestive system of the human body, and quickly recover the physiological function of the human body, thereby effectively realizing the liver nourishing and protecting capacity while improving the capacity of dispelling the effects of alcohol.

Drawings

FIG. 1 is a schematic flow diagram of the process of the present invention;

FIG. 2 is a flow chart of the coating process.

Detailed Description

Example 1

As shown in fig. 1, an anti-hangover and liver-protecting tablet comprises the following components in percentage by mass: 10% of hawthorn, 3% of kudzuvine root, 8.5% of corn oligopeptide powder, 6.3% of oyster peptide, 2.5% of xylo-oligosaccharide, 1.3% of vitamin C, 1.1% of L-leucine, 0.3% of L-glutamic acid, 0.05% of L-cysteine, 0.11% of glycine, 0.8% of citric acid, 1.5% of L-malic acid, 0.3% of taurine, 0.01% of aspartame (containing phenylalanine), 0.3% of potassium sulfacetamide, 1.3% of magnesium stearate, 0.1% of lycopene, 0.3% of curcumin and the balance of lactose.

A preparation method of an anti-alcohol liver-protecting tablet comprises the following steps:

s1, preparing extract powder, adding deionized water into the hawthorn and the kudzuvine root, decocting twice at a constant temperature of 90 ℃, wherein the decocting time is 1 hour each time, filtering and collecting decoction after the first decoction is finished, naturally cooling the decoction, the residual hawthorn and the kudzuvine root to the normal temperature, then adding deionized water into the residual hawthorn and the kudzuvine root for secondary decoction, filtering the secondary decoction after the decoction is finished, and mixing the filtered secondary decoction with the first decoction; then filtering the mixed decoction, collecting the filtrate in a centralized manner, heating and concentrating the filtrate at the constant temperature of 60 ℃ to obtain thick paste with the relative density of 1.35 after the filtrate is collected, finally drying the thick paste in vacuum, and crushing the dried solid material to obtain 80-mesh extract powder;

s2, mixing the materials, adding the extract powder obtained in the step S1, lactose, citric acid, L-malic acid and oyster peptide into a mixing device, mixing at the constant temperature of 20 ℃, adding vitamin C, aspartame, acesulfame potassium and taurine into a mixing machine for continuously mixing for 10 minutes after mixing for 1 minute, and then intensively storing the mixed solid materials in the mixing machine for later use;

s3, preparing a solution, after the step S2 is completed, adding lycopene into 1kg of deionized water and uniformly mixing for later use, and simultaneously adding curcumin into 1kg of deionized water and uniformly mixing for later use;

s4, granulating, wherein after the step S3 is completed, a lycopene aqueous solution is added into a mixer and mixed with solid materials in the mixer, then the mixture is stirred and mixed for 5 minutes through the mixer, then the mixture is filtered through a 12-mesh screen, the filtered mixed materials are added into the mixer again, then a curcumin aqueous solution is added into the mixer and mixed and stirred for 2 minutes, finally the mixture is transferred into a granulator and granulated through the 12-mesh screen, then the prepared semi-finished granules are dried for 1 hour at 50 ℃ in a hot air circulation oven, and finally granules are granulated through a 14-mesh screen to obtain finished product hangover alleviating granules;

and S5, coating, namely conveying the finished product of the hangover alleviating granules obtained in the step S4 into coating equipment, and coating a coating layer with the thickness of 1 mm on the outer surface of the hangover alleviating granules to obtain the finished product of the hangover alleviating and liver protecting tablet.

And C, concentrating the residual hawthorn and kudzu vine root residues and the filtered filter residues after the processing treatment in the step S1, adding saccharomycetes accounting for 1% of the total amount of the residues and the filter residues into the residues and the filter residues, uniformly mixing, pressing into a filter cake with a block structure, wherein the thickness of the filter cake is 3 cm, the length and the width of the filter cake are not more than 10 cm, and the water content of the filter cake is not more than 4%.

Meanwhile, the total amount of the deionized water in the step S1 is 2.5 times of the total amount of the hawthorn and the kudzuvine root.

It is emphasized that, in the step S5, the coating layer includes an auxiliary layer and a functional layer from the inside to the outside, wherein the thickness of the functional layer is 10% of the thickness of the auxiliary layer.

Further, the auxiliary layer is composed of the following substances in percentage by mass: the Chinese magnoliavine fruit honey powder comprises 10% of Chinese magnoliavine fruit powder, 3% of salvia miltiorrhiza powder, 3.5% of licorice powder, 2.3% of gardenia powder, 11% of yam powder, 5.3% of cassia seed powder and the balance of refined honey, wherein the Chinese magnoliavine fruit powder, the salvia miltiorrhiza powder, the licorice powder, the gardenia powder, the yam powder and the cassia seed powder are all 20 meshes, and the Chinese magnoliavine fruit powder, the salvia miltiorrhiza powder, the licorice powder, the gardenia powder, the yam powder and the cassia seed powder are all.

Meanwhile, the functional layer consists of the following substances in percentage by mass: 10% of L-arabinose, 5% of maltitol, 3.5% of carboxymethyl cellulose, 2.3% of sulfur-containing amino acid, 2.5% of inositol, 8.6% of glucose, 1% of acetic acid bacteria freeze-dried powder and the balance of milk powder.

As shown in fig. 2, a method for constructing an anti-hangover and liver-protecting tablet, comprises the following steps:

firstly, mixing materials for preparation, namely heating refined honey to a molten state, adding schisandra chinensis powder, salvia miltiorrhiza powder, liquorice powder, gardenia powder, yam powder and semen cassiae powder into the refined honey, and uniformly stirring to obtain a liquid auxiliary layer for later use; simultaneously stirring and mixing L-arabinose, maltitol, carboxymethyl cellulose, sulfur-containing amino acid, inositol, glucose, acetic acid bacteria lyophilized bacteria powder and milk powder at the constant temperature of 20 ℃ to obtain a powdery functional layer for later use;

secondly, primary coating, namely directly coating the liquid auxiliary layer prepared in the first step on the outer layer of the finished product hangover alleviating granule prepared in the step S4, granulating again, and performing air drying operation by using cold air at the temperature of-5 ℃ to obtain a semi-finished product hangover alleviating and liver protecting tablet;

and thirdly, press-molding, namely mixing the semi-finished product of the alcohol-relieving and liver-protecting tablet prepared in the second step with the powdery functional layer prepared in the first step, so that the powdery functional layer is coated outside the semi-finished product of the alcohol-relieving and liver-protecting tablet, and press-molding the mixture by a tablet press to obtain the finished product of the alcohol-relieving and liver-protecting tablet.

Example 2

As shown in fig. 1, an anti-hangover and liver-protecting tablet comprises the following components in percentage by mass: 22% of hawthorn, 7% of kudzuvine root, 17% of corn oligopeptide powder, 12.3% of oyster peptide, 5.8% of xylo-oligosaccharide, 2.7% of vitamin C, 3.5% of L-leucine, 1.4% of L-glutamic acid, 0.15% of L-cysteine, 1.4% of glycine, 3.5% of citric acid, 3.5% of L-malic acid, 1.8% of taurine, 0.21% of aspartame (containing phenylalanine), 0.35% of acesulfame potassium, 2.7% of magnesium stearate, 0.4% of lycopene, 1.1% of curcumin and the balance of lactose.

A preparation method of an anti-alcohol liver-protecting tablet comprises the following steps:

s1, preparing extract powder, adding deionized water into the hawthorn and the kudzuvine root, decocting twice at a constant temperature of 110 ℃, wherein the decocting time is 2 hours each time, filtering and collecting decoction after the first decoction is finished, naturally cooling the decoction, the residual hawthorn and the kudzuvine root to the normal temperature, then adding deionized water into the residual hawthorn and the kudzuvine root for secondary decoction, filtering the secondary decoction after the decoction is finished, and mixing the filtered secondary decoction with the first decoction; then filtering the mixed decoction, collecting the filtrate in a centralized manner, heating and concentrating the filtrate at the constant temperature of 80 ℃ to obtain thick paste with the relative density of 1.38 after the filtrate is collected, finally drying the thick paste in vacuum, and crushing the dried solid material to obtain extract powder of 500 meshes;

s2, mixing the materials, adding the extract powder obtained in the step S1, lactose, citric acid, L-malic acid and oyster peptide into a mixing device, mixing at the constant temperature of 40 ℃, adding vitamin C, aspartame, acesulfame potassium and taurine into a mixing machine for continuously mixing for 30 minutes after mixing for 3 minutes, and then intensively storing the mixed solid materials in the mixing machine for later use;

s3, preparing a solution, after the step S2 is completed, adding lycopene into 4kg of deionized water and uniformly mixing for later use, and simultaneously adding curcumin into 4kg of deionized water and uniformly mixing for later use;

s4, granulating, wherein after the step S3 is completed, a lycopene aqueous solution is added into a mixer and mixed with solid materials in the mixer, the mixture is stirred and mixed for 15 minutes through the mixer, the mixture is filtered through a 20-mesh screen, the filtered mixed materials are added into the mixer again, a curcumin aqueous solution is added into the mixer and mixed and stirred for 10 minutes, the mixture is transferred into a granulator and granulated through a 20-mesh screen, the prepared semi-finished granules are dried for 2 hours at 60 ℃ in a hot air circulation oven, and the granules are granulated through the 20-mesh screen to obtain finished product hangover alleviating granules;

and S5, coating, namely conveying the finished product of the hangover alleviating granules obtained in the step S4 into coating equipment, and coating a coating layer with the thickness of 5 mm on the outer surface of the hangover alleviating granules to obtain the finished product of the hangover alleviating and liver protecting tablet.

Meanwhile, after the processing treatment in the step S1, the residual hawthorn and kudzu vine root residues and the filtered filter residues are gathered, saccharomycetes accounting for 10% of the total amount of the residues and the filter residues are added into the residues and the filter residues and are uniformly mixed, then the mixture is pressed into a filter cake with a block structure, the thickness of the filter cake is 10 cm, the length and the width of the filter cake are not more than 30 cm, the water content of the filter cake is not more than 4%, and in the step S1, the total amount of deionized water is 5 times of the total amount of the hawthorn and.

In addition, in the step S5, the coating layer includes an auxiliary layer and a functional layer from the inside to the outside, wherein the thickness of the functional layer is 30% of the thickness of the auxiliary layer.

The auxiliary layer is mainly composed of the following substances in percentage by mass: 15% of schisandra chinensis powder, 7% of salvia miltiorrhiza powder, 7% of licorice powder, 5.3% of gardenia powder, 21% of yam powder, 11.7% of semen cassiae powder and the balance of refined honey, wherein the schisandra chinensis powder, the salvia miltiorrhiza powder, the licorice powder, the gardenia powder, the yam powder and the semen cassiae powder are all 100 meshes, and the schisandra chinensis powder, the salvia miltiorrhiza powder, the licorice powder, the gardenia powder, the yam powder and the semen cassiae powder are all freeze-dried powders.

In addition, the functional layer is composed of the following substances in percentage by mass: 15% of L-arabinose, 11% of maltitol, 7.1% of carboxymethyl cellulose, 5.3% of sulfur-containing amino acid, 4.1% of inositol, 14.5% of glucose, 2.5% of acetic acid bacteria freeze-dried powder and the balance of milk powder.

As shown in fig. 2, a method for constructing an anti-hangover and liver-protecting tablet, comprises the following steps:

firstly, mixing materials for preparation, namely heating refined honey to a molten state, adding schisandra chinensis powder, salvia miltiorrhiza powder, liquorice powder, gardenia powder, yam powder and semen cassiae powder into the refined honey, and uniformly stirring to obtain a liquid auxiliary layer for later use; simultaneously stirring and mixing L-arabinose, maltitol, carboxymethyl cellulose, sulfur-containing amino acid, inositol, glucose, acetic acid bacteria lyophilized bacteria powder and milk powder at the constant temperature of 40 ℃ to obtain a powdery functional layer for later use;

secondly, primary coating, namely directly coating the liquid auxiliary layer prepared in the first step on the outer layer of the finished product hangover alleviating granule prepared in the step S4, granulating again, and performing air drying operation by using cold air at 5 ℃ to obtain a semi-finished product hangover alleviating and liver protecting tablet;

and thirdly, press-molding, namely mixing the semi-finished product of the alcohol-relieving and liver-protecting tablet prepared in the second step with the powdery functional layer prepared in the first step, so that the powdery functional layer is coated outside the semi-finished product of the alcohol-relieving and liver-protecting tablet, and press-molding the mixture by a tablet press to obtain the finished product of the alcohol-relieving and liver-protecting tablet.

Example 3

As shown in fig. 1, an anti-hangover and liver-protecting tablet comprises the following components in percentage by mass: 15% of hawthorn, 5% of kudzuvine root, 11% of corn oligopeptide powder, 8.3% of oyster peptide, 3.8% of xylo-oligosaccharide, 1.8% of vitamin C, 2.5% of L-leucine, 0.9% of L-glutamic acid, 0.1% of L-cysteine, 0.5% of glycine, 2.5% of citric acid, 2.4% of L-malic acid, 0.8% of taurine, 0.11% of aspartame (containing phenylalanine), 0.31% of acesulfame potassium, 1.8% of magnesium stearate, 0.2% of lycopene, 0.8% of curcumin and the balance of lactose.

A preparation method of an anti-alcohol liver-protecting tablet comprises the following steps:

s1, preparing extract powder, adding deionized water into the hawthorn and the kudzuvine root, decocting twice at a constant temperature of 100 ℃, wherein the decocting time is 1.2 hours each time, filtering and collecting decoction after the first decoction is finished, naturally cooling the decoction, the residual hawthorn and the kudzuvine root to the normal temperature, then adding deionized water into the residual hawthorn and the kudzuvine root for secondary decoction, filtering the secondary decoction after the decoction is finished, and mixing the secondary decoction with the first decoction; then filtering the mixed decoction, collecting the filtrate in a centralized manner, heating and concentrating the filtrate at the constant temperature of 70 ℃ to obtain thick paste with the relative density of 1.36 after the filtrate is collected, finally drying the thick paste in vacuum, and crushing the dried solid material to obtain extract powder of 100 meshes;

s2, mixing the materials, adding the extract powder obtained in the step S1, lactose, citric acid, L-malic acid and oyster peptide into a mixing device, mixing at the constant temperature of 30 ℃, adding vitamin C, aspartame, acesulfame potassium and taurine into a mixing machine for continuously mixing for 15 minutes after mixing for 2 minutes, and then intensively storing the mixed solid materials in the mixing machine for later use;

s3, preparing a solution, after the step S2 is completed, adding lycopene into 2kg of deionized water and uniformly mixing for later use, and simultaneously adding curcumin into 2.5kg of deionized water and uniformly mixing for later use;

s4, granulating, wherein after the step S3 is completed, the lycopene aqueous solution is added into a mixer and mixed with solid materials in the mixer, then the mixture is stirred and mixed for 10 minutes through the mixer, then the mixture is filtered through a 15-mesh screen, the filtered mixed materials are added into the mixer again, then the curcumin aqueous solution is added into the mixer and mixed and stirred for 8 minutes, finally the mixture is transferred into a granulator and granulated through a 15-mesh screen, then the prepared semi-finished granules are dried for 1.2 hours at 55 ℃ in a hot air circulation oven, and finally the granules are granulated through the 15-mesh screen to obtain finished product particles for dispelling the effects of the alcohol;

and S5, coating, namely conveying the finished product of the hangover alleviating granules obtained in the step S4 into coating equipment, and coating a coating layer with the thickness of 3 mm on the outer surface of the hangover alleviating granules to obtain the finished product of the hangover alleviating and liver protecting tablet.

Preferably, the hawthorn and kudzu vine root residues left after the processing treatment in the step S1 and the filtered filter residues are collected, saccharomycetes accounting for 8% of the total amount of the residues and the filter residues are added into the residues and the filter residues and are uniformly mixed, and then the mixture is pressed into a filter cake with a block structure, wherein the thickness of the filter cake is 5 cm, the length and the width of the filter cake are not more than 30 cm, and the water content of the filter cake is not more than 4%.

In addition, the total amount of the deionized water in the step of S1 is 3 times of the total amount of the hawthorn and the kudzuvine root.

It is emphasized that, in the step S5, the coating layer includes an auxiliary layer and a functional layer from the inside to the outside, wherein the thickness of the functional layer is 15% of the thickness of the auxiliary layer.

Meanwhile, the auxiliary layer consists of the following substances in percentage by mass: 12% of schisandra chinensis powder, 5% of salvia miltiorrhiza powder, 4.7% of licorice powder, 3.3% of gardenia powder, 15% of yam powder, 7.7% of semen cassiae powder and the balance of refined honey, wherein the schisandra chinensis powder, the salvia miltiorrhiza powder, the licorice powder, the gardenia powder, the yam powder and the semen cassiae powder are all 80 meshes, and the schisandra chinensis powder, the salvia miltiorrhiza powder, the licorice powder, the gardenia powder, the yam powder and the semen cassiae powder are all freeze-dried powders.

Meanwhile, the functional layer consists of the following substances in percentage by mass: 13% of L-arabinose, 8% of maltitol, 6.1% of carboxymethyl cellulose, 4.3% of sulfur-containing amino acid, 3.1% of inositol, 12.5% of glucose, 1.5% of acetic acid bacteria freeze-dried powder and the balance of milk powder.

As shown in fig. 2, a method for constructing an anti-hangover and liver-protecting tablet, comprises the following steps:

firstly, mixing materials for preparation, namely heating refined honey to a molten state, adding schisandra chinensis powder, salvia miltiorrhiza powder, liquorice powder, gardenia powder, yam powder and semen cassiae powder into the refined honey, and uniformly stirring to obtain a liquid auxiliary layer for later use; simultaneously stirring and mixing L-arabinose, maltitol, carboxymethyl cellulose, sulfur-containing amino acid, inositol, glucose, acetic acid bacteria lyophilized bacteria powder and milk powder at the constant temperature of 25 ℃ to obtain a powdery functional layer for later use;

secondly, primary coating, namely directly coating the liquid auxiliary layer prepared in the first step on the outer layer of the finished product hangover alleviating granule prepared in the step S4, granulating again, and performing air drying operation by using cold air at 0 ℃ to obtain a semi-finished product hangover alleviating and liver protecting tablet;

and thirdly, press-molding, namely mixing the semi-finished product of the alcohol-relieving and liver-protecting tablet prepared in the second step with the powdery functional layer prepared in the first step, so that the powdery functional layer is coated outside the semi-finished product of the alcohol-relieving and liver-protecting tablet, and press-molding the mixture by a tablet press to obtain the finished product of the alcohol-relieving and liver-protecting tablet.

Example 4

As shown in fig. 1, an anti-hangover and liver-protecting tablet comprises the following components in percentage by mass: 20% of hawthorn, 6.1% of kudzuvine root, 14.3% of corn oligopeptide powder, 9.3% of oyster peptide, 3.8% of xylo-oligosaccharide, 2.2% of vitamin C, 2.3% of L-leucine, 0.9% of L-glutamic acid, 0.11% of L-cysteine, 0.9% of glycine, 1.5% of citric acid, 2.1% of L-malic acid, 1.1% of taurine, 0.13% of aspartame (containing phenylalanine), 0.34% of acesulfame potassium, 2% of magnesium stearate, 0.25% of lycopene, 0.4% of curcumin and the balance of lactose.

A preparation method of an anti-alcohol liver-protecting tablet comprises the following steps:

s1, preparing extract powder, adding deionized water into the hawthorn and the kudzuvine root, decocting twice at a constant temperature of 95 ℃, wherein the decocting time is 1.8 hours each time, filtering and collecting decoction after the first decoction is finished, naturally cooling the decoction, the residual hawthorn and the kudzuvine root to the normal temperature, then adding deionized water into the residual hawthorn and the kudzuvine root for secondary decoction, filtering the secondary decoction after the decoction is finished, and mixing the secondary decoction with the first decoction; then filtering the mixed decoction, collecting the filtrate in a centralized manner, heating and concentrating the filtrate at the constant temperature of 75 ℃ to obtain thick paste with the relative density of 1.37 after the filtrate is collected, finally drying the thick paste in vacuum, and crushing the dried solid material to obtain extract powder of 200 meshes;

s2, mixing the materials, adding the extract powder obtained in the step S1, lactose, citric acid, L-malic acid and oyster peptide into a mixing device, mixing at the constant temperature of 35 ℃, adding vitamin C, aspartame, acesulfame potassium and taurine into a mixing machine for continuously mixing for 20 minutes after mixing for 2 minutes, and then intensively storing the mixed solid materials in the mixing machine for later use;

s3, preparing a solution, after the step S2 is completed, adding the lycopene into 2.1kg of deionized water and uniformly mixing for later use, and simultaneously adding the curcumin into 3.5kg of deionized water and uniformly mixing for later use;

s4, granulating, wherein after the step S3 is completed, the lycopene aqueous solution is added into a mixer and mixed with solid materials in the mixer, then the mixture is stirred and mixed for 11 minutes through the mixer, then the mixture is filtered through a 15-mesh screen, the filtered mixed materials are added into the mixer again, then the curcumin aqueous solution is added into the mixer and mixed and stirred for 8 minutes, finally the mixture is transferred into a granulator and granulated through a 20-mesh screen, then the prepared semi-finished granules are dried for 1.7 hours at 55 ℃ in a hot air circulation oven, and finally the granules are granulated through the 15-mesh screen to obtain finished product particles for dispelling the effects of the alcohol;

and S5, coating, namely conveying the finished product of the hangover alleviating granules obtained in the step S4 into coating equipment, and coating a coating layer with the thickness of 4 mm on the outer surface of the hangover alleviating granules to obtain the finished product of the hangover alleviating and liver protecting tablet.

Meanwhile, after the processing treatment in the step S1, the residual hawthorn and kudzu vine root residues and the filtered filter residues are gathered, saccharomycetes accounting for 6% of the total amount of the residues and the filter residues are added into the residues and the filter residues and are uniformly mixed, then the mixture is pressed into a filter cake with a block structure, the thickness of the filter cake is 9 cm, the length and the width of the filter cake are not more than 30 cm, the water content of the filter cake is not more than 4%, and in the step S1, the total amount of deionized water is 3.4 times of the total amount of the hawthorn and.

Meanwhile, in the step S5, the coating layer includes an auxiliary layer and a functional layer from the inside to the outside, wherein the thickness of the functional layer is 28% of the thickness of the auxiliary layer.

The auxiliary layer is mainly composed of the following substances in percentage by mass: 11% of schisandra chinensis powder, 4.1% of salvia miltiorrhiza powder, 4.6% of licorice powder, 3.3% of gardenia powder, 14.5% of yam powder, 9.7% of cassia seed powder and the balance of refined honey, wherein the schisandra chinensis powder, the salvia miltiorrhiza powder, the licorice powder, the gardenia powder, the yam powder and the cassia seed powder are all 80 meshes, and the schisandra chinensis powder, the salvia miltiorrhiza powder, the licorice powder, the gardenia powder, the yam powder and the cassia seed powder are all freeze-dried powders.

Meanwhile, the functional layer consists of the following substances in percentage by mass: 11.5 percent of L-arabinose, 7 percent of maltitol, 6.1 percent of carboxymethyl cellulose, 4.3 percent of sulfur-containing amino acid, 3.5 percent of inositol, 10.5 percent of glucose, 1.3 percent of acetic acid bacteria freeze-dried powder and the balance of milk powder.

As shown in fig. 2, a method for constructing an anti-hangover and liver-protecting tablet, comprises the following steps:

firstly, mixing materials for preparation, namely heating refined honey to a molten state, adding schisandra chinensis powder, salvia miltiorrhiza powder, liquorice powder, gardenia powder, yam powder and semen cassiae powder into the refined honey, and uniformly stirring to obtain a liquid auxiliary layer for later use; simultaneously stirring and mixing L-arabinose, maltitol, carboxymethyl cellulose, sulfur-containing amino acid, inositol, glucose, acetic acid bacteria lyophilized bacteria powder and milk powder at the constant temperature of 28 ℃ to obtain a powdery functional layer for later use;

secondly, primary coating, namely directly coating the liquid auxiliary layer prepared in the first step on the outer layer of the finished product hangover alleviating granule prepared in the step S4, granulating again, and performing air drying operation by using cold air at 3 ℃ to obtain a semi-finished product hangover alleviating and liver protecting tablet;

and thirdly, press-molding, namely mixing the semi-finished product of the alcohol-relieving and liver-protecting tablet prepared in the second step with the powdery functional layer prepared in the first step, so that the powdery functional layer is coated outside the semi-finished product of the alcohol-relieving and liver-protecting tablet, and press-molding the mixture by a tablet press to obtain the finished product of the alcohol-relieving and liver-protecting tablet.

In practical use, after the invention is taken, the invention enters the digestive tract of a human body and is characterized in that:

firstly, a functional layer of a coating layer is dissolved firstly, and after the functional layer is dissolved, on one hand, L-arabinose of the functional layer can effectively inhibit the absorption capacity of a human digestive system and reduce the absorption capacity of the human body to alcohol, on the other hand, carboxymethyl cellulose contains sulfur amino acid, inositol and glucose and can effectively nourish the digestive system and reduce the loss of alcohol and medicaments to the digestive system;

then, the medicine and nutrient components of the coated layer schisandra chinensis powder, the salvia miltiorrhiza powder, the liquorice powder, the gardenia powder, the yam powder and the cassia seed powder enter the blood from the copper drum digestive system, so that the purposes of nourishing the digestive system, the liver and the kidney, improving the metabolism level of human organ systems, accelerating the decomposition and excretion efficiency of alcohol, reducing the harm of alcohol to the human body, improving the cell activity of the digestive system, the liver and the kidney of the human body, reducing the damage of alcohol to human cells, effectively improving the absorption, transportation and transformation capacity of the human body to nutrient substances and keeping the digestive system, the liver and the kidney of the human body at a higher physiological activity level are achieved;

finally, after the coating layer preliminarily inhibits the alcohol absorption capacity of the human digestive system and preliminarily protects and improves the physiological level of the human digestive system, liver, kidney and other organs, the absorption, transportation and transformation capacities of nutritional ingredients and medicinal ingredients of components such as hawthorn, kudzuvine root, corn oligopeptide powder, oyster peptide, xylo-oligosaccharide, vitamin, L-leucine, L-glutamic acid, L-cysteine, glycine, citric acid, L-malic acid, taurine, aspartame (containing phenylalanine), acesulfame potassium, magnesium stearate, lycopene, curcumin, lactose and the like which form the anti-alcoholism granule are effectively improved through a digestive system with high physiological activity level, the defect that the efficacy of the medicinal ingredients is not fully exerted due to the insufficient function of the digestive system of a human body in the traditional anti-alcoholism product is overcome, thereby further improving the efficiency of relieving alcoholism and the nourishing capability to human liver and other organs while relieving alcoholism.

The invention has wide raw material sources, low cost and small toxic and side effects, and on one hand, the invention can effectively reduce the absorption efficiency and absorption amount of human body to alcohol, effectively improve the metabolism level of human body, accelerate the decomposition capability of human body to alcohol and the excretion capability of alcohol from human body, thereby achieving the purposes of quickly dispelling the effects of alcohol and sobering up and reducing the adverse effects of alcohol on the digestive system and nervous system of human body; on the other hand, the alcohol-containing liver-protecting health-care wine can effectively reduce the damage of alcohol to the liver, prevent fat from accumulating at the liver part, effectively improve the regeneration capacity of stem cells, recover and improve the comprehensive physiological function of the liver, promote bile secretion, further improve the digestive capacity of a human body, eliminate the burden and adverse effect of alcohol on the digestive system of the human body, and quickly recover the physiological function of the human body, thereby effectively realizing the liver nourishing and protecting capacity while improving the capacity of dispelling the effects of alcohol.

The foregoing shows and describes the general principles and broad features of the present invention and advantages thereof. It will be understood by those skilled in the art that the present invention is not limited to the embodiments described above, which are described in the specification and illustrated only to illustrate the principle of the present invention, but that various changes and modifications may be made therein without departing from the spirit and scope of the present invention, which fall within the scope of the invention as claimed. The scope of the invention is defined by the appended claims and equivalents thereof.

Claims (9)

1. An anti-alcohol liver-protecting tablet is characterized in that: the alcohol-relieving and liver-protecting tablet is composed of the following substances in percentage by mass: 10-22% of hawthorn, 3-7% of radix puerariae, 8.5-17% of corn oligopeptide powder, 6.3-12.3% of oyster peptide, 2.5-5.8% of xylo-oligosaccharide, 1.3-2.7% of vitamin C, 1.1-3.5% of L-leucine, 0.3-1.4% of L-glutamic acid, 0.05-0.15% of L-cysteine, 0.11-1.4% of glycine, 0.8-3.5% of citric acid, 1.5-3.5% of L-malic acid, 0.3-1.8% of taurine, 0.01-0.21% of aspartame (containing phenylalanine), 0.3-0.35% of acesulfame potassium, 1.3-2.7% of magnesium stearate, 0.1-0.4% of lycopene, 0.3-1.1% of curcumin and the balance of lactose.

2. A preparation method of a tablet for relieving alcoholism and protecting liver is characterized by comprising the following steps: the preparation method of the anti-alcohol liver-protecting tablet comprises the following steps:

s1, preparing extract powder, adding deionized water into the hawthorn and the kudzuvine root, decocting twice at a constant temperature of 90-110 ℃, wherein the decocting time is 1-2 hours each time, filtering and collecting decoction after the first decoction is finished, naturally cooling the decoction, the residual hawthorn and the kudzuvine root to normal temperature, then adding deionized water into the residual hawthorn and the kudzuvine root for secondary decoction, filtering the secondary decoction after the decoction is finished, and mixing the filtered decoction with the first decoction; then filtering the mixed decoction, collecting the filtrate in a centralized manner, heating and concentrating the filtrate at the constant temperature of 60-80 ℃ to obtain thick paste with the relative density of 1.35-1.38 after the filtrate is collected, finally drying the thick paste in vacuum, and crushing the dried solid material to obtain extract powder of 80-500 meshes;

s2, mixing the materials, adding the extract powder obtained in the step S1, lactose, citric acid, L-malic acid and oyster peptide into a mixing device, mixing at the constant temperature of 20-40 ℃, adding vitamin C, aspartame, acesulfame potassium and taurine into a mixing machine for continuously mixing for 10-30 minutes after mixing for 1-3 minutes, and then intensively storing the mixed solid materials in the mixing machine for later use;

s3, preparing a solution, after the step S2 is completed, adding the lycopene into 1-4 kg of deionized water and uniformly mixing for later use, and simultaneously adding the curcumin into 1-4 kg of deionized water and uniformly mixing for later use;

s4, granulating, wherein after the step S3 is completed, a lycopene water solution is added into a mixer and mixed with solid materials in the mixer, the mixture is stirred and mixed for 5-15 minutes through the mixer, the mixture is filtered through a 12-20-mesh screen, the filtered mixed materials are added into the mixer again, a curcumin water solution is added into the mixer and mixed and stirred for 2-10 minutes, finally the mixture is transferred into a granulator and granulated through a 12-20-mesh screen, the prepared semi-finished granules are dried for 1-2 hours at 50-60 ℃ in a hot air circulation oven, and finally, the granules are granulated through a 14-20-mesh screen to obtain finished product particles for dispelling effects of alcohol;

and S5, coating, namely conveying the finished product of the hangover alleviating granules obtained in the step S4 into coating equipment, and coating a coating layer with the thickness of 1-5 mm on the outer surface of the hangover alleviating granules to obtain the finished product of the hangover alleviating and liver protecting tablet.

3. The construction method of the alcohol-relieving liver-protecting tablet according to claim 2, wherein the construction method comprises the following steps: and (3) concentrating the residual hawthorn and kudzu root residues and the filtered filter residues after the processing treatment in the step S1, adding saccharomycetes accounting for 1-10% of the total amount of the residues and the filter residues into the residues and the filter residues, uniformly mixing, pressing into a filter cake with a block structure, wherein the thickness of the filter cake is 3-10 cm, the length and the width of the filter cake are not more than 30 cm, and the water content of the filter cake is not more than 4%.

4. The construction method of the alcohol-relieving liver-protecting tablet according to claim 2, wherein the construction method comprises the following steps: the total amount of the deionized water in the step S1 is 2.5-5 times of the total amount of the hawthorn and the kudzuvine root.

5. The construction method of the alcohol-relieving liver-protecting tablet according to claim 2, wherein the construction method comprises the following steps: in step S5, the coating layer includes an auxiliary layer and a functional layer from the inside to the outside, wherein the thickness of the functional layer is 10% to 30% of the thickness of the auxiliary layer.

6. The construction method of the alcohol-relieving liver-protecting tablet according to claim 5, wherein the construction method comprises the following steps: the auxiliary layer is composed of the following substances in percentage by mass: 10-15% of schisandra chinensis powder, 3-7% of salvia miltiorrhiza powder, 3.5-7% of liquorice powder, 2.3-5.3% of gardenia powder, 11-21% of yam powder, 5.3-11.7% of cassia seed powder and the balance of refined honey.

7. The construction method of the alcohol-relieving liver-protecting tablet according to claim 5, wherein the construction method comprises the following steps: the schisandra chinensis powder, the salvia miltiorrhiza powder, the liquorice powder, the gardenia powder, the yam powder and the cassia seed powder are all 20-100 meshes, and the schisandra chinensis powder, the salvia miltiorrhiza powder, the liquorice powder, the gardenia powder, the yam powder and the cassia seed powder are all freeze-dried powders.

8. The construction method of the alcohol-relieving liver-protecting tablet according to claim 5, wherein the construction method comprises the following steps: the functional layer is composed of the following substances in percentage by mass: 10-15% of L-arabinose, 5-11% of maltitol, 3.5-7.1% of carboxymethyl cellulose, 2.3-5.3% of sulfur-containing amino acid, 2.5-4.1% of inositol, 8.6-14.5% of glucose, 1-2.5% of acetic acid bacteria freeze-dried powder and the balance of milk powder.

9. The construction method of the alcohol-relieving liver-protecting tablet according to claim 2, wherein the construction method comprises the following steps: when the coating operation is performed in the step S5:

firstly, mixing materials for preparation, namely heating refined honey to a molten state, adding schisandra chinensis powder, salvia miltiorrhiza powder, liquorice powder, gardenia powder, yam powder and semen cassiae powder into the refined honey, and uniformly stirring to obtain a liquid auxiliary layer for later use; simultaneously stirring and mixing L-arabinose, maltitol, carboxymethyl cellulose, sulfur-containing amino acid, inositol, glucose, acetic acid bacteria freeze-dried bacteria powder and milk powder at the constant temperature of 20-40 ℃ to obtain a powdery functional layer for later use;

secondly, primary coating, namely directly coating the liquid auxiliary layer prepared in the first step on the outer layer of the finished product hangover alleviating granule prepared in the step S4, granulating again, and carrying out air drying operation by cold wind at-5 ℃ to obtain a semi-finished product hangover alleviating and liver protecting tablet;

and thirdly, press-molding, namely mixing the semi-finished product of the alcohol-relieving and liver-protecting tablet prepared in the second step with the powdery functional layer prepared in the first step, so that the powdery functional layer is coated outside the semi-finished product of the alcohol-relieving and liver-protecting tablet, and press-molding the mixture by a tablet press to obtain the finished product of the alcohol-relieving and liver-protecting tablet.

Images