CN111449093A - Natural essential oil composition with antibacterial and disinfecting effects and application thereof - Google Patents
Natural essential oil composition with antibacterial and disinfecting effects and application thereof Download PDFInfo
- Publication number
- CN111449093A CN111449093A CN202010428748.7A CN202010428748A CN111449093A CN 111449093 A CN111449093 A CN 111449093A CN 202010428748 A CN202010428748 A CN 202010428748A CN 111449093 A CN111449093 A CN 111449093A
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- Prior art keywords
- oil
- essential
- antibacterial
- cinnamon
- artemisia
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Abstract
The invention belongs to the technical field of disinfection products, and relates to a natural essential oil composition with an antibacterial effect for daily use and an application thereof. The composition comprises one or more of essential oils, preferably artemisia halodendron oil, artemisia annua oil, citronella oil, geranium oil, clove essential oil, vanillyl butyl ether, litsea cubeba oil, cinnamon oil, lemongrass oil, schizonepeta oil, rosemary oil, eucalyptus globulus oil, orange peel oil, peppermint oil, citrus oil, patchouli oil and eucalyptus citriodora oil. The essential oil composition can be prepared into daily sterilizing and killing products such as a no-clean skin care gel, an antibacterial wet tissue, an antibacterial spray, an antibacterial sachet and the like, and can be added into daily chemical products such as a facial cleanser, a hand sanitizer, a shampoo and the like to obtain the sterilizing and bacteriostasis effects on the surface of a washed object.
Description
Technical Field
The invention belongs to the technical field of disinfection products, and relates to a natural essential oil composition with an antibacterial effect for daily use and an application thereof.
Background
COVID-19 is a newly discovered acute respiratory infectious disease that lacks an effective control and treatment method. Compared with SARS, COVID-19 has wider spread range in the global scope and more related countries. The current internationally accepted preventive means are social isolation, wearing of masks, keeping the environment ventilated and clean, and keeping hands sanitary. The contact with public articles and parts in public places is reduced as much as possible; returning from public place, after cough and covering hands, before meal and after defecation, washing hands with running water by using liquid soap or perfumed soap, or using no-wash liquid soap containing alcohol component; when the hands are not determined to be clean, the hands are prevented from contacting the mouth, the nose, the eyes and the like. The clinical effects of the series of measures on controlling public health emergencies such as SARS and H1N1 influenza are remarkable, which indicates that keeping the environment clean and hand hygiene is an effective measure for preventing the occurrence of infectious diseases.
Since the living external environment is complex and changeable and the disinfectant with flammable and combustible properties is inconvenient to carry in some special conditions such as taking a vehicle like an airplane, a train and the like, the disinfectant which is safe, effective and non-flammable needs to be provided. How to guarantee indoor space or carry out preventive disinfection in narrow and closed spaces such as private cars for a long time in winter heating seasons and central air-conditioning environments will block transmission ways of various infectious diseases and needs to provide disinfectants for keeping the spaces clean. Meanwhile, how to provide safe and effective disinfection protection for hands and other skin exposed to the external environment in an environment inconvenient for hand washing without causing the dryness of the stratum corneum of the skin to reduce the barrier effect is also a problem needing deep thought.
Disclosure of Invention
The invention aims to provide an essential oil composition with disinfection and sterilization effects.
The invention also aims to provide the application of the essential oil composition with the disinfection and sterilization effects in preparing disinfection products.
The invention is realized by the following technical scheme:
the invention provides an essential oil composition with disinfection and sterilization effects, which comprises artemisia argyi oil, artemisia halodendron seed oil, artemisia apiacea oil, artemisia annua oil, pyrethrum extract, cedar wood oil, thuja oil, phellodendron amurense oil, camphor essential oil, tarragon essential oil, citronella oil, litsea cubeba oil, cinnamon oil, lemongrass oil, mint oil, rosemary oil, eucalyptus oil, catnip oil, cinnamon oil, eucalyptus oil, mint oil, eucalyptus globulus oil, geranium oil, orange peel oil, rotenone, peucedanum root volatile oil, eucommia bark leaf extract, liquidambar formosana flower oil, cassia twig alcohol, amomum cardamomum oil, peppermint oil, whiteflower oil, citrus essential oil, mikania oil, azadirachtin, citrus oil, agastache oil, coumarin, eucalyptus leaf essential oil, lemon eucalyptus oil, paeonol, thyme essential oil, clove essential oil, vanillyl butyl ether, parsley essential oil, cinnamon essential oil, hydroxycitronellalang propionate, One or more of hydroxycitronellal 1, 2-propanediol acetal, citronellal 1, 3-propanediacetal, (E) -2-hexenal, 8-hydroxydihydrocarvyl formate, campholenic aldehyde-1, 3-propanediol, geranium extract, peppermint extract and pyrethroid compound.
Preferably, the essential oil composition with disinfection and sterilization effects comprises one or more of artemisia halodendron oil, artemisia annua oil, citronella oil, geranium oil, clove essential oil, vanillyl butyl ether, litsea cubeba oil, cinnamon oil, lemongrass oil, schizonepeta oil, rosemary oil, eucalyptus globulus oil, orange peel oil, peppermint oil, citrus oil, patchouli oil and eucalyptus citriodora oil.
More preferably, the essential oil composition with disinfection and sterilization effects comprises one or more of artemisia halodendron oil, artemisia annua oil, citronella oil, geranium oil, clove essential oil, vanillyl butyl ether, litsea cubeba oil, rosemary oil, lemon grass oil, schizonepeta oil, cinnamon oil, eucalyptus globulus oil, orange peel oil, peppermint oil, citrus oil, patchouli oil and eucalyptus citriodora oil.
Further, the essential oil composition with the disinfection and sterilization effects comprises two, three or more of sweet wormwood oil, citronella oil, catnip oil, cinnamon oil, lemon oil, orange peel oil, geranium oil, clove essential oil and vanillyl butyl ether.
Still further, the present invention prefers a combination of essential oils:
1. artemisia halodendron seed oil, artemisia oil, geranium oil and citronella oil;
2. sweet wormwood oil, cinnamon oil, lemon grass oil and catnip oil;
3. artemisia halodendron oil, geranium oil, cinnamon oil, and eucalyptus oil;
4. clove oil, artemisia annua oil, eucalyptus globulus oil and eucalyptus citriodora leaf oil;
5. artemisia annua oil, citronella oil, litsea cubeba oil and vanillyl butyl ether;
6. artemisia halodendron oil, artemisia oil, catnip oil and cinnamon oil;
7. geranium oil, clove oil, citronella oil, and eucalyptus oil;
8. artemisia oil, cinnamon oil, geranium oil, and vanillyl butyl ether;
9. clove oil, sweet wormwood oil and vanillyl butyl ether;
10. clove oil, geranium oil and citronella oil;
11. sweet wormwood oil, citronella oil and eucalyptus oil;
12. sweet wormwood oil, cinnamon oil and citrus oil;
13. artemisia annua oil, citronella oil, and cinnamon oil;
14. eucalyptus oil, eucalyptus globulus oil, and vanillyl butyl ether;
15. citrus oil, citronella oil, and vanillyl butyl ether;
16. geranium oil, clove essential oil, citronella oil, cinnamon oil and vanillyl butyl ether.
When the two essential oil compositions are mixed for use, the weight ratio of the two essential oil compositions is 1-10:10-1, preferably 1-5: 5-1; when the three are mixed for use, the weight ratio of the three is 1-10:1-10:1-10, preferably 1-5:1-5:1-5, more preferably 1-3: 1-3: 1-3; when four kinds of the components are mixed, the weight ratio of the four kinds of the components is 1-10:1-10:1-10:1-10, preferably 1-5:1-5:1-5:1-5, more preferably 1-3: 1-3: 1-3: 1-3; when a plurality of compounds are used in combination, the ratio of the plurality is 1-10:1-10:1-10:1-10, preferably 1-5:1-5:1-5:1-5. When five or more than five are used in combination, the ratio of each component is 1-10:1-10, preferably 1-5:1-5, more preferably 1-3: 1-3.
The essential oil composition of the invention may be a combination of the following essential oils:
5-15 g of geranium oil, 10-15 g of clove essential oil, 5-15 g of citronella oil, 15-25 g of cinnamon oil, 5-10 g of vanillyl butyl ether
Wherein:
geranium oil: clove essential oil: citronella oil: cinnamon oil: vanillyl butyl ether 1-3: 2-3: 1-3: 3-5: 1-2;
preferably:
geranium oil: clove essential oil: citronella oil: cinnamon oil: vanillyl butyl ether 1-2: 2-3: 2-3: 4-5: 1-2.
The invention also provides application of the essential oil composition in preparation of a disinfection product.
The essential oil composition can be prepared into daily sterilizing and killing products such as a no-clean skin care gel, an antibacterial wet tissue, an antibacterial spray, an antibacterial sachet and the like, and can be added into daily chemical products such as a facial cleanser, a hand sanitizer, a shampoo and the like to obtain the sterilizing and bacteriostasis effects on the surface of a washed object.
In the antibacterial leave-on skin care gel, the antibacterial wet tissue, the antibacterial spray and the antibacterial sachet, the addition amount of the essential oil composition is 1-50% of the total weight of the product, and the balance is conventional additives such as a carrier, a solvent, an emulsifier, conventional additives and the like, wherein the solvent is water or alkyl alcohol, the alkyl alcohol is C1-C4 alcohol, preferably ethanol, and the volume concentration is 50-98%.
The addition amount of the essential oil composition of the daily chemical products such as the facial cleanser, the hand sanitizer, the shampoo and the like is 1-50% of the total weight of the product, and the balance is normal ingredients for preparing the daily chemical products, such as a carrier, a solvent, an emulsifier, conventional additives and the like, the solvent is water or alkyl alcohol, the alkyl alcohol is C1-C4 alcohol, preferably ethanol, and the volume concentration is 50-98%.
The essential oil composition can be prepared into an antibacterial skin-care wash-free gel, and the antibacterial wash-free gel is prepared by adding conventional auxiliary materials into the antibacterial essential oil composition. The antibacterial skin-care leave-on gel comprises the following components in parts by weight (percentage):
the essential oil composition can be prepared into an antibacterial skin-care wet tissue, so that the non-woven fabric contains a compound antibacterial essential oil solution, and the formula of the compound antibacterial solution is as follows:
antibacterial essential oil composition 45-65 g alcohol (75% concentration by volume) 40m L;
the essential oil composition can be prepared into antibacterial essential oil spray, and is prepared by mixing the essential oil composition with other conventional auxiliary materials to form a solution; and spraying the antibacterial essential oil solution to the space through the spray head to kill or inhibit microorganisms in the space. The formula of the antibacterial essential oil spray is as follows:
30-60 g of antibacterial essential oil composition, 30-50 g of Tween
Adding water to a constant volume of 40m L;
the essential oil composition can be used for treating the sachet and fillers therein to prepare an antibacterial sachet, and the antibacterial sachet is worn on the body or placed in a small-range closed space such as a vehicle to play a role in disinfection and sterilization.
The antibacterial essential oil composition consists of the following essential oils in parts by weight:
or
Further, the present invention preferably selects the antibacterial essential oil spray solution formulated as follows: adding citronella oil, cinnamon oil, geranium oil, clove essential oil and Tween into a container for uniform emulsification, then adding water for dispersion, and stirring uniformly to obtain the antibacterial essential oil solution.
The invention preferably selects the antibacterial skin-care wet tissue prepared from the compound antibacterial essential oil solution prepared by the following method: adding citronella oil, cinnamon oil, geranium oil, clove essential oil, lemon oil and orange peel oil into a container, uniformly stirring, adding 75% alcohol by volume concentration, rapidly stirring, and uniformly stirring to obtain the compound antibacterial essential oil solution.
On one hand, the essential oil composition provided by the invention has the advantages that phenolic substances in all components enter the cell wall of the microorganism, so that the function of the cell membrane is influenced, the content of the cell is promoted to leak, the cell structure is damaged, and the microorganism is killed; on the other hand, terpenoids in the components have inhibition effects on microbial metabolism, reduced coenzyme and other enzyme activities, so that the microbial metabolism is disordered, and the bacteriostatic effect is achieved. The two effects can play a synergistic role to achieve the effects of improving inflammation diminishing and antibiosis and improving the durability of the essential oil. The sterilization rate of the composition reaches more than 95 percent, and the composition is environment-friendly and safe. Can kill bacteria or viruses in a broad spectrum, has no irritation or anaphylactic reaction to skin, is safe and nontoxic to human bodies, does not contain harmful substances such as formaldehyde, heavy metal ions and the like, and meets the requirement of environmental protection. Meanwhile, the essential oil is free of flammability and explosiveness, has a certain moisturizing effect on skin after being used, is easy to prepare gel, disinfectant wet tissue and the like, is easy to prepare space disinfectant, disinfectant sachet and the like due to volatility and persistence of the essential oil, and has wide application value.
Detailed Description
In order to make the objects, technical solutions and advantages of the present invention more apparent, the present invention is further described in detail with reference to the following embodiments. It should be understood that the specific embodiments described herein are merely illustrative of the invention and are not intended to limit the invention. In the present invention, all amounts and parts are by weight and all raw materials are commercially available, unless otherwise specified.
Example 1 preparation of an antibacterial skin care Wet wipes
Enabling the non-woven fabric to contain a compound antibacterial essential oil solution, wherein the formula of the compound antibacterial essential oil solution comprises:
the compound antibacterial essential oil solution is prepared by the following method:
adding oleum Artemisiae Annuae, citronella oil, oleum Cinnamomi, geranium oil, oleum Caryophylli, water-soluble vitamin E, and emulsifier into the container, and stirring to obtain compound antibacterial essential oil solution. And (3) immersing the non-woven fabric into the antibacterial essential oil solution to obtain the wet tissue with the antibacterial effect.
According to the invention, the components are matched according to a specific weight ratio, the effect of killing pathogenic bacteria is synergistically enhanced, the action time can be prolonged, and the sterilization time effectiveness is improved. Moreover, the composition has good repelling and avoiding effects on mites compared with the mites, thereby reducing the infection of insect-borne pathogens. The invention has good bactericidal and bacteriostatic effects on staphylococcus aureus, candida albicans and mites.
Example 2
The compound essential oil wash-free gel is prepared according to the following mixture ratio:
the no-wash gel is prepared by the following method:
adding the sweet wormwood oil, the catnip oil, the citronella oil and the eucalyptus citriodora leaf oil into a container according to the formula amount, uniformly stirring, adding 75% alcohol by volume concentration, stirring, adding carbomer, and uniformly stirring to obtain the compound essential oil no-wash gel.
According to the invention, the components are matched according to a specific weight ratio, so that the sterilization effect is synergistically enhanced, the action time can be prolonged, and the sterilization time effectiveness is improved. The invention has good bactericidal and bacteriostatic effects on staphylococcus aureus and candida albicans.
Example 3
Preparing a compound antibacterial essential oil spray according to the following parts by weight:
according to the invention, the components are matched according to a specific weight ratio, so that the sterilization effect is synergistically enhanced, the action time can be prolonged, and the sterilization time effectiveness is improved. The composition has good repelling and avoiding effects on mites compared with the mite, thereby reducing the infection of insect-borne pathogens. The staphylococcus aureus, the candida albicans and the mites have good sterilization, bacteriostasis and evasion effects.
Example 4
The compound antibacterial essential oil of the embodiment 3 is added into wet tissues, hand washing liquids, hair washing products and laundry detergents, the addition amount of the compound antibacterial essential oil is 1-5% of the total weight, and other conventional additives and main components are added. The composition has good repelling and avoiding effects on mites compared with the mite, thereby reducing the infection of insect-borne pathogens. The invention has good effects of sterilization, bacteriostasis and evasion to staphylococcus aureus, candida albicans and acarid.
Example 5
The essential oil antibacterial agent is any one of artemisia halodendron seed oil, artemisia annua oil, cedar oil, thujor oil, cedar wood essential oil, camphor essential oil, citronella oil, litsea cubeba oil, cinnamon oil, lemongrass oil, mint oil, rosemary oil, eucalyptus oil, catnip oil, clove oil, eucalyptus oil, mint oil, eucalyptus globulus oil, rotenone, peppermint oil, citrus essential oil, mikania micrantha oil, azadirachtin, citronella oil, geranium oil, citrus oil, erysipelas oil, eucalyptus leaf essential oil, eucalyptus citriodora leaf oil and vanillylbutyl ether, and is added into wet tissues, hand washing liquids, hair washing products, fabric softeners and laundry detergents in an amount of 1-5 percent, and other conventional additives and main components are added. According to the invention, the components are matched according to a specific weight ratio, so that the sterilization effect is synergistically enhanced, the action time can be prolonged, and the sterilization time effectiveness is improved. The composition has good repelling and avoiding effects on mites compared with the mite, thereby reducing the infection of insect-borne pathogens. The invention has good effects of sterilization, bacteriostasis and evasion to staphylococcus aureus, candida albicans and acarid.
Example 6
Experiment for killing and avoiding pathogenic microorganisms by adopting combined essential oil
Essential oil composition for experiments:
5-15 g of geranium oil, 10-15 g of clove essential oil, 5-15 g of citronella oil, 15-25 g of cinnamon oil, 5-10 g of vanillyl butyl ether
Geranium oil: clove essential oil: citronella oil: cinnamon oil: vanillyl butyl ether 1-3: 2-3: 1-3: 3-5: 1-2;
preferably: geranium oil: clove essential oil: citronella oil: cinnamon oil: vanillyl butyl ether 1-2: 2-3: 2-3: 4-5: 1-2;
preparing 80g of essential oil compositions 1,2, 3 and 4 respectively according to the following formula;
essential oil composition 1: geranium oil: clove essential oil: citronella oil: cinnamon oil: vanillyl butyl ether 1: 2: 1: 3: 1
Essential oil composition 2: geranium oil: clove essential oil: citronella oil: cinnamon oil: vanillyl butyl ether 1: 3: 3: 5: 2
Essential oil composition 3: geranium oil: clove essential oil: citronella oil: cinnamon oil: vanillyl butyl ether 2: 2: 2: 4: 1
Essential oil composition 4: geranium oil: clove essential oil: citronella oil: cinnamon oil: vanillyl butyl ether 3: 3: 3: 5: 2, experimental method:
preparing agar plates, dripping 0.2ml of bacterial liquid after each agar plate is solidified, uniformly coating, taking 5m L of essential oil composition (15 g/L, ethanol is used as a solvent) to prepare bacteriostatic tablets, putting the dried tablets on the agar plates, culturing for 24 hours at 37 ℃, and observing the size of a bacteriostatic ring, the measuring diameter of a vernier caliper, statistical data and experimental results shown in table 1.
In addition, 5m L of vanillyl butyl ether, citronella oil, cinnamon oil, geranium oil and clove oil (15 g/L, solvent is ethanol) are respectively taken to prepare bacteriostatic tablets, the dried tablets are placed on a bacterial plate and cultured for 24 hours at 37 ℃, and the size of a bacteriostatic zone, the vernier caliper diameter, statistical data and experimental results are shown in table 1.
TABLE 1 experiments on the killing and avoidance of pathogenic organisms in essential oils
Claims (11)
1. An essential oil composition with antibacterial and disinfectant effects is characterized by comprising artemisia argyi oil, artemisia halodendron oil, artemisia apiacea oil, artemisia annua oil, chrysanthemum artemisia annua oil, pyrethrum extract, cedar wood oil, thuja oil, phellodendron amurense oil, cedar wood essential oil, camphor essential oil, tarragon essential oil, citronella oil, litsea cubeba oil, cinnamon oil, lemongrass oil, mint oil, rosemary oil, eucalyptus oil, catnip oil, cinnamon oil, eucalyptus oil, mint oil, eucalyptus globulus oil, geranium oil, orange peel oil, rotenone, peucedanum essential oil, eucommia ulmoides leaf extract, liquidambar formosana flower oil, cassia twig oil, amomum cardamomum oil, peppermint oil, erysipelas oil, citrus essential oil, mikania micrantha oil, azadirachtin, citrus oil, agastache rugo oil, coumarin, eucalyptus leaf essential oil, limonin, paeonol, thyme essential oil, clove essential oil, vanillyl butyl ether, parsley essential oil, cinnamon essential oil, hydroxycitronellalang propionate, One or more of hydroxycitronellal 1, 2-propanediol acetal, citronellal 1, 3-propanediacetal, (E) -2-hexenal, 8-hydroxydihydrocarvyl formate, campholenic aldehyde-1, 3-propanediol, geranium extract, peppermint extract and pyrethroid compound.
2. The essential oil composition with antibacterial and disinfectant effects as claimed in claim 1, comprising one or more of artemisia halodendron oil, artemisia annua oil, citronella oil, geranium oil, clove essential oil, vanillyl butyl ether, litsea cubeba oil, cinnamon oil, lemongrass oil, catnip oil, rosemary oil, eucalyptus globulus oil, orange peel oil, peppermint oil, citrus oil, patchouli oil and eucalyptus citriodora oil.
3. An essential oil composition having antibacterial and disinfectant effects according to any one of claims 1-2, comprising a mixture of two or more of sweet wormwood oil, citronella oil, catnip oil, lemon oil, orange peel oil, geranium oil, clove essential oil, and vanillyl butyl ether.
4. The essential oil composition having antibacterial and disinfectant effects according to any one of claims 1 to 3, wherein when both are used in admixture, the weight ratio of the two is 1-10:10-1, preferably 1-5: 5-1; when the three components are mixed for use, the weight ratio of the three components is 1-10:1-10:1-10, preferably 1-5:1-5:1-5, more preferably 1-3: 1-3: 1-3; when four kinds of the components are mixed, the weight ratio of the four kinds of the components is 1-10:1-10:1-10:1-10, preferably 1-5:1-5:1-5:1-5, more preferably 1-3: 1-3: 1-3: 1-3; when five or more than five are mixed for use, the weight ratio of each component is 1-10:1-10, preferably 1-5:1-5, more preferably 1-3: 1-3.
5. An antimicrobial disinfecting essential oil composition according to any one of claims 1 to 4 wherein the essential oil composition is one of the following combinations:
(1) artemisia halodendron seed oil, artemisia oil, geranium oil and citronella oil;
(2) sweet wormwood oil, cinnamon oil, lemon grass oil and catnip oil;
(3) artemisia halodendron oil, geranium oil, cinnamon oil, and eucalyptus oil;
(4) clove oil, sweet wormwood oil, cinnamon oil and eucalyptus citriodora leaf oil;
(5) artemisia annua oil, citronella oil, litsea cubeba oil and vanillyl butyl ether;
(6) artemisia halodendron oil, artemisia oil, catnip oil and cinnamon oil;
(7) geranium oil, clove oil, citronella oil, and eucalyptus oil;
(8) artemisia oil, cinnamon oil, geranium oil, and vanillyl butyl ether;
(9) clove oil, cinnamon oil, and vanillyl butyl ether;
(10) clove oil, geranium oil and citronella oil;
(11) sweet wormwood oil, citronella oil and eucalyptus oil;
(12) sweet wormwood oil, cinnamon oil and citrus oil;
(13) artemisia annua oil, citronella oil, and cinnamon oil;
(14) eucalyptus oil, eucalyptus globulus oil, and vanillyl butyl ether;
(15) citrus oil, citronella oil, and vanillyl butyl ether;
(16) geranium oil, clove essential oil, citronella oil, cinnamon oil and vanillyl butyl ether.
6. Use of the essential oil composition having antibacterial and disinfectant effects as claimed in any one of claims 1 to 5 for the preparation of a disinfectant product.
7. The use according to claim 6, wherein the biocidal product is: antibacterial wash-free gel, antibacterial wet tissue, antibacterial spray, and antibacterial sachet.
9. the use of claim 7, wherein the antimicrobial essential oil spray formulation comprises:
30-60 g of antibacterial essential oil composition Tween-8030-50 g
Adding water to a constant volume of 40m L.
10. The use of claim 7, wherein the antimicrobial wet wipe comprises a compound antimicrobial solution having the following formula:
the antibacterial essential oil composition comprises 45-65 g of alcohol (75% concentration by volume) 40m L.
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Cited By (12)
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