CN110251217B - Embryo transplantation system - Google Patents
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- CN110251217B CN110251217B CN201910565622.1A CN201910565622A CN110251217B CN 110251217 B CN110251217 B CN 110251217B CN 201910565622 A CN201910565622 A CN 201910565622A CN 110251217 B CN110251217 B CN 110251217B
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods
- A61B17/42—Gynaecological or obstetrical instruments or methods
- A61B17/425—Gynaecological or obstetrical instruments or methods for reproduction or fertilisation
- A61B17/435—Gynaecological or obstetrical instruments or methods for reproduction or fertilisation for embryo or ova transplantation
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- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Heart & Thoracic Surgery (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pregnancy & Childbirth (AREA)
- Gynecology & Obstetrics (AREA)
- Transplantation (AREA)
- Biomedical Technology (AREA)
- Reproductive Health (AREA)
- Medical Informatics (AREA)
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- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
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Abstract
The embodiment of the invention discloses an embryo transplantation system, and relates to the technical field of medical instruments. The embryo transfer system comprises a main tube, wherein an image sensor is arranged at the first end of the main tube, and an optical path channel and an embryo conveying channel are respectively arranged in the axial direction of the main tube and in parallel with the image sensor. The image sensor is used for shooting an image of the inside of a human body and outputting the image in real time, and the position of a uterine cavity can be observed in the embryo transfer process based on the image, so that the current situation that blind operation is carried out in the existing embryo transfer process only by means of the hand feeling and experience of a doctor is changed. The invention is suitable for gynecological examination and treatment operation.
Description
Technical Field
The invention relates to the technical field of medical instruments, in particular to an embryo transplantation system.
Background
Embryo transplantation is to transplant an embryo to a proper uterine cavity position so that the embryo can be implanted on an endometrium with good receptivity, and whether the embryo can be transplanted to the proper uterine cavity position is an important factor influencing the embryo transplantation result and the clinical pregnancy rate.
At present, the embryo transplantation operation is usually performed by blind operation only by the hand feeling and experience of doctors, the requirement on professional literacy of the doctors is high, and the success rate of transplanting the embryo to a proper uterine cavity position is low.
Disclosure of Invention
In view of this, the embodiment of the present invention provides an embryo transfer system, which can observe the position of a uterine cavity during embryo transfer to change the current situation that the current embryo transfer is performed only by the hand feeling and experience of a doctor for blind operation, so as to improve the success rate of transferring an embryo to a proper position of the uterine cavity.
In order to achieve the purpose, the invention adopts the following technical scheme:
the embryo transplantation system comprises a main body tube, wherein an image sensor is arranged at the first end of the main body tube, and an optical path channel and an embryo conveying channel are respectively arranged in the axial direction of the main body tube and in parallel with the image sensor.
Preferably, the embryo conveying channel is eccentrically arranged relative to the central line of the main tube, the image sensor is arranged adjacent to the embryo conveying channel, the optical path channel comprises a first optical path channel and a second optical path channel, and the first optical path channel and the second optical path channel are respectively arranged on two sides of the image sensor.
Preferably, the image sensor is a 0 < size specification ≦ 1/18 inch CMOS image sensor.
Preferably, the embryo conveying channel is a cylindrical channel, and the diameter of the cylindrical channel is more than 0 and less than or equal to 1.5 mm.
Preferably, the main tube has an elbow at a first end, the image sensor is disposed at an end of the elbow, and the optical path channel and the embryo conveying channel are opened at the end of the elbow.
Preferably, the first end of the main tube has a rounded configuration.
Preferably, 0 < the lens angle of view of the image sensor ≦ 120 °.
Preferably, the image sensor is electrically connected to an optical processing device, and the optical processing device is disposed at the second end of the main tube.
Preferably, an embryo conveying device is inserted in the embryo conveying channel, the embryo conveying device comprises a suction cup for adsorbing embryos, and the suction cup is connected to the air suction assembly through an air pipe; the sucking disc is close to the first end setting of main part pipe, the subassembly of breathing in is located the second end of main part pipe.
Preferably, a medium injection channel is arranged in the axial direction of the main body pipe and in parallel with the embryo conveying channel.
The embryo transfer system provided by the embodiment of the invention comprises a main tube, wherein an image sensor is arranged at the first end of the main tube, and an optical path channel and an embryo conveying channel are respectively arranged in the axial direction of the main tube and in parallel with the image sensor. When the embryo transplantation operation is carried out, the main body tube is inserted into a human body, an image of the interior of the human body, such as a uterine cavity and peripheral organs or tissues thereof, is shot through the image sensor at the first end of the main body tube, the image is output, an operator can observe the exact position of the uterine cavity through the image, and the operation is carried out based on the exact position of the uterine cavity presented by the image, so that the current situation that the existing embryo transplantation is carried out blind operation only by virtue of the hand feeling and experience of a doctor is changed; further, under the clear visual field presented by the image, because the embryo conveying channel is arranged on the circumference of the main body tube, the embryo can be conveniently conveyed to a proper position of the uterine cavity through the embryo conveying channel, so that the success rate of the operation can be improved to a certain extent.
Drawings
In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the drawings used in the description of the embodiments or the prior art will be briefly described below, it is obvious that the drawings in the following description are only some embodiments of the present invention, and for those skilled in the art, other drawings can be obtained according to the drawings without creative efforts.
FIG. 1 is a schematic diagram of an embodiment of an embryo transfer system of the present invention;
FIG. 2 is a schematic view of a partial structure of the embryo transplantation system of FIG. 1 according to an embodiment A;
FIG. 3 is a schematic view of a partial structure at position A of another embodiment of the embryo transplantation system shown in FIG. 1;
FIG. 4 is a schematic view of a partial structure of the embryo transfer system of FIG. 1 in accordance with still another embodiment A.
Detailed Description
Embodiments of the present invention will be described in detail below with reference to the accompanying drawings.
It should be apparent that numerous technical details are set forth in the following specific examples in order to provide a more thorough description of the present invention, and it should be apparent to one skilled in the art that the present invention may be practiced without some of these details. In addition, some methods, means, components and applications thereof known to those skilled in the art are not described in detail in order to highlight the gist of the present invention, but the implementation of the present invention is not affected thereby. The embodiments described herein are only a few embodiments of the present invention, and not all embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
The embryo transplantation system provided by the embodiment of the invention is suitable for gynecology, such as examination, diagnosis and operation treatment of human organs such as uterus, fallopian tube and the like, is also suitable for embryo transplantation operation, and is simple and convenient to operate.
Referring to fig. 1 to 4, the embryo transfer system comprises: the main body tube 1 is provided with an image sensor 2 at a first end of the main body tube 1, and an optical path channel 3 and an embryo transfer channel 4 are respectively provided in the axial direction of the main body tube 1 and in parallel with the image sensor 2.
Wherein, the first end of the main tube 1 is the end of the main tube which is inserted into the human body firstly when in work, namely the front end in general; specifically, the main tube is made of medical plastic materials, such as polyvinyl chloride (PVC), Polyethylene (PE), polypropylene (PP), Polystyrene (PS) and K resin, acrylonitrile-butadiene-styrene (ABS), Polycarbonate (PC), Polytetrafluoroethylene (PTFE) polyether block polyamide PEBAX/thermoplastic polyurethane elastomer rubber TPU, and the like; preferably made of medical hard plastic materials, and when the main body pipe is a round pipe, the diameter of the main body pipe is more than 0mm and less than or equal to 3.7 mm; the hysteroscope has small hardness and small diameter, has small harm to a patient, and can solve the technical problem that the hysteroscope cannot enter the oviduct communicated with the cervix due to the large diameter of the hysteroscope body, so that the embryo transplantation system can also realize the examination and the diagnosis of whether the oviduct has pathological changes. The image sensor 2 is used for shooting images of an examination or operation part and organs or tissues nearby the examination or operation part, and can output the images; specifically, the image sensor may be electrically connected to the optical processing device 5 to output an image of the human body examination or operation site or the vicinity thereof to the optical processing device 5, and the optical processing device 5 may display the image as a two-dimensional or three-dimensional image on the display after processing the image; the optical processing device 5 is provided at a second end of the main tube 1, which is generally referred to as a rear end of the main tube. The optical path channel 3 is used for providing the image sensor with the illumination condition required for taking an image in a human body. The embryo transfer channel 4 is used to transfer the embryo into position in the uterine cavity.
It can be understood that, the embryo transplantation system of the present embodiment can not only capture the image of the target part, such as the uterus, by the image sensor 2 and display it in real time, but also can inspect and treat the lesion of the human body organ by observing the image; particularly, in the embryo transplantation operation, the position of the uterine cavity can be clearly seen in the image, so that the embryo transplantation operation is visualized, and the current situation that the existing embryo transplantation is blindly operated only by the hand feeling and experience of doctors is changed; in addition, an embryo transfer device, such as a catheter for embryo transfer, can be inserted through the embryo conveying channel 4, so that the visualized embryo implantation operation can be performed, and the success rate of the operation can be improved to a certain extent.
In addition, because the patients need to make ovum hastening needles when preparing for the early period of the embryo transplantation operation, the patients are very painful during the preparation period, and if the embryo transplantation operation is not successful for many times, the psychological burden of the patients can be greatly caused.
The embryo transplantation system can also enable doctors to see the ovum implantation process in the operation, thereby improving the success rate of the operation, and reducing the physical pain and psychological burden of patients caused by repeated ovum-hastening needle for many times due to unsuccessful operation.
In this embodiment, specifically, the image sensor 2 is an electronic CMOS image sensor, the size specification of the image sensor 2 is greater than 0 and less than or equal to 1/18 inches, the image sensor 2 has at least 16 ten thousand effective pixels, and the cost thereof is low, with the progress of science and technology, the cost of the CMOS image sensor will be further reduced, from the viewpoint of hygiene and convenience of medical equipment, it is a development trend that the embryo transplantation system of this embodiment will gradually become a disposable medical equipment appliance in the future, and reasonable guess is made from the structure and manufacturing cost of the embryo transplantation system of this embodiment, so that the embryo transplantation system can be conveniently used as a disposable appliance in the future. The field angle of the lens of the image sensor 2 is more than 0 and less than or equal to 120 degrees. This can enlarge the field of view of the operator inside the human body.
In one embodiment, two image sensors 2 may be arranged side by side at intervals to form binocular stereo vision, and two images of the position of the examination or operation site, for example, the uterine cavity, are taken from different angles, so that the optical processing device can acquire three-dimensional geometric information of the target site according to the position difference between corresponding position points in the two images to generate a three-dimensional image display.
The embryo transfer system provided by the embodiment of the invention comprises a main tube 1, wherein an image sensor 2 is arranged at the first end of the main tube 1, and an optical path channel 3 and an embryo conveying channel 4 are respectively arranged in the axial direction of the main tube 1 and in parallel with the image sensor 2. When an embryo transplantation operation is carried out, the main tube 1 is inserted into a human body, images of the interior of the human body, such as a uterine cavity and peripheral organs or tissues thereof, are shot through the image sensor 2 at the first end of the main tube 1, the images are output, an operator can observe the exact position of the uterine cavity through the images, and the operation is carried out based on the exact position of the uterine cavity presented by the images, so that the current situation that the existing embryo transplantation is carried out blind operation only by means of the hand feeling and experience of a doctor is changed; further, under the clear visual field presented by the image, because the embryo conveying channel 4 is arranged on the circumference of the main tube 1, the embryo can be conveniently conveyed to a proper position of the uterine cavity through the embryo conveying channel 4, thereby improving the success rate of the operation to a certain extent.
Referring to fig. 2 to 4, in this embodiment, as an alternative embodiment, the embryo conveying channel 4 is eccentrically arranged relative to the central line of the main tube 1, the image sensor 2 is arranged adjacent to the embryo conveying channel 4, the optical path channel 3 includes a first optical path channel 31 and a second optical path channel 32, and the first optical path channel 31 and the second optical path channel 32 are respectively arranged at two sides of the image sensor 2. Like this, through rational utilization main part pipe 1 cross-section spatial layout each structure, can guarantee to shoot required illumination condition when, make structural arrangement comparatively compact.
Referring to fig. 2 to 4, in the present embodiment, two sides of the image sensor 2 are: the image sensor 2 is arranged on two sides which are not intersected with the central connecting line of the image sensor 2 and the embryo conveying channel 4; an optical fiber is arranged in the light path channel 3, the optical fiber is provided with a cold light source input end, and a cold light source connector is arranged on the cold light source input end; wherein the cold light source input end is located at the end of the optical fiber, which is located near the second end of the main tube 1.
The first optical path channel 31, the second optical path channel 32 and the embryo transfer channel 4 may share one channel in the axial full length of the main tube 1, or may be respectively disposed in different channels in the portion of the main tube 1 axially located at the second end of the main tube 1, and share one channel in the portion located at the first end of the main tube 1.
Referring to FIG. 2, in one embodiment, the embryo transfer channel 4 is internally tangent to the main tube 1, the image sensor 2 is disposed adjacent to the embryo transfer channel 4, and the first optical channel 31 and the second optical channel 32 are disposed on two sides of the image sensor 2.
Referring to fig. 3, in another embodiment, the image sensor 2, the first optical path channel 31 and the second optical path channel 32 are disposed in the channel with the rounded crescent cross section at the whole axial length of the main tube 1 or at a part of the length near the first end of the main tube 1, the embryo transfer channel 4 is disposed at the concave profile side of the channel with the rounded crescent cross section, and the first optical path channel 31 and the second optical path channel 32 are disposed at two sides of the image sensor 2.
Referring to FIG. 4, in another embodiment, the embryo transfer channel 4 and the image sensor 2 are symmetrically disposed about a first axial section of the main tube 1, the first light path channel 31 and the second light path channel 32 are disposed on two sides of the image sensor 2, and the first light path channel 31 and the second light path channel 32 are symmetrically disposed about a second axial section, wherein the first axial section is perpendicular to the second axial section.
Referring to FIG. 3, in one embodiment of the present invention, the main tube 1 is further provided with a medium injection channel 6 axially in parallel with the embryo transfer channel 4.
In the embodiment, the diameter of the medium injection channel 6 is more than 0 and less than or equal to 0.8 mm; the medium can be liquid or gas, when the embryo transfer system is used for examination, diagnosis or operation treatment, the liquid or gas can be injected into the human body through the medium injection channel 6, and the auxiliary main body tube 1 is easily inserted into a preset position in the human body, so that the pain of the human body is relieved to a certain extent. For example, when the embryo transfer implantation operation is performed by using the embryo transfer system of the present embodiment, it is necessary to insert the main body tube 1 into the vicinity of the uterus via the vagina, and during the insertion, the vagina is closed, and there is pain in directly inserting the main body tube 1 into the human body, and if a liquid or a gas is injected into the path of the main body tube 1 through the medium injection passage 6, the path of the main body tube 1 is first flushed and then inserted forward, and thus the main body tube 1 can be inserted into a predetermined position smoothly and the pain of the human body can be reduced.
It is understood that, when the embryo transfer operation is performed by those skilled in the art, according to the technical teaching of the present invention, the injection pressure of the liquid or gas can be selected to smoothly break the advancing path of the main tube 1; on the basis of the requirement, the injection pressure can be comprehensively selected by combining the impact force acceptable by the human body; the injection pressure parameters are not listed in detail here.
In another embodiment of the present invention, the main tube 1 has a bend 11 at the first end, the image sensor 2 is disposed at the end of the bend 11, and the optical path channel 3 and the embryo conveying channel 4 are opened at the end of the bend 11; through the main tube 1 with the elbow 11, the position of the uterus or the uterine cavity of the uterus is better adapted to facilitate the operation when the examination diagnosis or the operation treatment is performed.
When the main body pipe 1 is a round pipe, the diameter of the elbow 11 is more than 0 and less than or equal to 3.7mm, and the length is less than or equal to 1000 mm. The parameters are determined based on human physiology, particularly according to the positions and mutual position relations of vagina and/or cervix and uterus, when a system with the parameters is used for examination or diagnosis and treatment, the operation is convenient, and simultaneously, the resistance of the elbow 11 arranged at the front end of the main tube 1 and inserted into the human body is reduced as much as possible, so that the pain of the human body in the examination or diagnosis and treatment process is relieved to a certain extent.
In the embodiment, specifically, the first end of the main tube 1 has a rounded structure; because the first end of the main body tube 1 is provided with the rounded structure, the pain that the main body tube 1 touches the human body in the process of being inserted into the human body can be relieved, and the injury to the internal tissues or organs of the human body can be avoided to a certain extent.
In one embodiment of the invention, the embryo conveying channel 4 is a cylindrical channel, and the diameter of the cylindrical channel is more than 0 and less than or equal to 1.5 mm.
In another embodiment of the present invention, an embryo conveying device (not shown in the figure) is inserted into the embryo conveying channel 4, and the embryo conveying device comprises a suction cup for sucking embryos, and the suction cup is connected to a suction assembly through a trachea; the sucker is arranged close to the first end of the main pipe 1, and the air suction assembly is located at the second end of the main pipe 1.
In this embodiment, the subassembly of breathing in includes the solenoid valve, and when needs carried the embryo, press the inching switch of solenoid valve, adsorb the embryo on the sucking disc, through the human inside image of image sensor 2 shooting, observe the specific position in palace chamber, under the image guide that appears, the sucking disc is put the embryo to the suitable position in palace chamber.
The embryo transplantation system of the invention can not only detect and diagnose the pathological changes of human organs such as uterine cavity, etc., but also observe whether the fallopian tube has pathological changes or not because of the small diameter, thereby enlarging the range of the prior gynecological hysteroscope operation, and improving the accuracy of detection, diagnosis and treatment to a certain extent because the embryo transplantation system can go deep into pathological change tissues or organs for detection or diagnosis and treatment. In addition, through the integrated multichannel, insert embryo transfer pipe through embryo input channel, once can alleviate the secondary in the misery of human direct insertion, in addition, under the clear field of vision that the image sensor 2 shot provided, through embryo input channel, can conveniently carry out embryo implantation operation, replaced the mode that relies on doctor's feeling and experience to carry out blind operation at present, thereby also can improve the operation success rate to a certain extent.
It is noted that, herein, the terms "upper", "lower", and the like, indicate orientations or positional relationships and are used for convenience in describing the present invention and for simplicity in description, but do not indicate or imply that the indicated device or element must have a particular orientation, be constructed and operated in a particular orientation, and thus should not be construed as limiting the present invention. Unless expressly stated or limited otherwise, the terms "mounted," "connected," and "connected" are intended to be inclusive and mean, for example, that they may be fixedly connected, detachably connected, or integrally connected; may be directly connected or indirectly connected through an intermediate. Relational terms such as first and second, and the like may be used solely to distinguish one entity or action from another entity or action without necessarily requiring or implying any actual such relationship or order between such entities or actions. Also, the terms "comprises," "comprising," or any other variation thereof, are intended to cover a non-exclusive inclusion, such that a process, method, article, or apparatus that comprises a list of elements does not include only those elements but may include other elements not expressly listed or inherent to such process, method, article, or apparatus. Without further limitation, an element defined by the phrase "comprising an … …" does not exclude the presence of other identical elements in a process, method, article, or apparatus that comprises the element. As will be appreciated by one of ordinary skill in the art, the situation may be specified.
The above description is only for the specific embodiment of the present invention, but the scope of the present invention is not limited thereto, and any changes or substitutions that can be easily conceived by those skilled in the art within the technical scope of the present invention are included in the scope of the present invention. Therefore, the protection scope of the present invention shall be subject to the protection scope of the claims.
Claims (8)
1. An embryo transplantation system comprises a main body tube, wherein an image sensor is arranged at a first end of the main body tube, and an optical path channel and an embryo conveying channel are respectively arranged in the axial direction of the main body tube and in parallel with the image sensor; the image sensor is electrically connected to the optical processing device, and the optical processing device is arranged at the second end of the main body pipe; the embryo conveying channel is eccentrically arranged relative to the central line of the main tube, and the image sensor is arranged adjacent to the embryo conveying channel;
the first end of the main tube is provided with an elbow, the image sensor is arranged at the end part of the elbow, and the light path channel and the embryo conveying channel are opened at the end part of the elbow;
the two image sensors are arranged side by side at intervals and used for shooting two images of an examination or operation part from different angles so that the optical processing device generates a three-dimensional image display according to the position difference between corresponding position points in the two images; the light path channel is internally provided with an optical fiber, the optical fiber is provided with a cold light source input end, and the cold light source input end is provided with a cold light source connector; wherein the cold light source input end is located at the end of an optical fiber, and the end of the optical fiber is located near the second end of the main tube;
a medium injection channel is arranged in the axial direction of the main body pipe and is parallel to the embryo conveying channel;
light path includes first light path passageway and second light path passageway, first light path passageway and second light path passageway set up respectively in image sensor's both sides, image sensor, first light path passageway and second light path passageway locate the crescent cross-sectional passageway that has the radius angle jointly at main part pipe axial full length or the partial length that is close to the first end of main part pipe in, embryo transfer passage locates the indent profile side of the crescent cross-sectional passageway that has the radius angle.
2. The system of claim 1, wherein the image sensor is a 0 < specification ≦ 1/18 inch CMOS image sensor.
3. The system of claim 1 or 2, wherein the embryo transfer channel is a cylindrical channel, and the diameter of the cylindrical channel is 0 < 1.5 mm.
4. The system of claim 1, wherein the main tube first end has a rounded configuration.
5. The system of claim 1, wherein 0 < a lens field angle of the image sensor ≦ 120 °.
6. The system of claim 1, wherein an embryo transport device is inserted into the embryo transport channel, the embryo transport device comprising a suction cup for holding an embryo, the suction cup being connected to a suction assembly via an air tube; the sucker is arranged close to the first end of the main body pipe, and the air suction assembly is located at the second end of the main body pipe.
7. The system of claim 1, wherein the main tube is made of a medical grade plastic material.
8. The system of claim 1, wherein 0 < the main tube outside diameter ≦ 3.7 mm.
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| Application Number | Priority Date | Filing Date | Title |
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| CN201910565622.1A CN110251217B (en) | 2019-06-26 | 2019-06-26 | Embryo transplantation system |
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| CN201910565622.1A CN110251217B (en) | 2019-06-26 | 2019-06-26 | Embryo transplantation system |
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| CN110251217B true CN110251217B (en) | 2021-02-19 |
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| CN112168314A (en) * | 2020-10-20 | 2021-01-05 | 太平洋康泰科学仪器（济南）有限公司 | Puncture ovum-taking device with heat-insulating structure |
| CN116687534B (en) * | 2023-08-02 | 2023-11-07 | 新光维医疗科技(苏州)股份有限公司 | Insertion assembly and endoscope |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8292798B2 (en) * | 2004-06-08 | 2012-10-23 | Eurica Califorrniaa | Incubator for babies before implantation |
| CN105636500A (en) * | 2013-05-17 | 2016-06-01 | 恩多巧爱思股份有限公司 | Multiple viewing elements endoscope having two front service channels |
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| Publication number | Priority date | Publication date | Assignee | Title |
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