CN110025539A - One kind is from osmotrophy type cosmetics and preparation method - Google Patents
One kind is from osmotrophy type cosmetics and preparation method Download PDFInfo
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/55—Phosphorus compounds
- A61K8/553—Phospholipids, e.g. lecithin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
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- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
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- A61K8/65—Collagen; Gelatin; Keratin; Derivatives or degradation products thereof
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
- A61K8/732—Starch; Amylose; Amylopectin; Derivatives thereof
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- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
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- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9789—Magnoliopsida [dicotyledons]
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- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/02—Preparations for care of the skin for chemically bleaching or whitening the skin
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Abstract
The present invention relates to one kind from osmotrophy type cosmetics and preparation method, belongs to cosmetic technical field.The technical problem to be solved by the present invention is to provide one kind from osmotrophy type cosmetics and preparation method.Collagen, hyaluronic acid, Propiram and Hippophae Rhamnoides L. juice are uniformly dispersed by the preparation method, and hydrogel solution is then added, and are concentrated as paste, load collagen, hyaluronic acid and stablize with hydrogel；By lactalbumin liquid by freeze-drying, high-pressure spray-drying, a nanometer Whey protein micelles are obtained, lactalbumin micelle and concentrate, phosphatide, tristerin, jelly powder are dispersed, are obtained a kind of from osmotrophy type cosmetics.The method of the present invention is simple, low in cost, thus obtained cosmetics, and low in cost, good penetrability is full of nutrition, and Skin Cell vigor can be improved, and improves blood circulation, improves whitening, beauty treatment, soothing effect.
Description
Technical field
The present invention relates to one kind from osmotrophy type cosmetics and preparation method, belongs to cosmetic technical field.
Background technique
With the development of the social economy, people's lives level is continuously improved, life is become increasingly by the normality having enough to eat and wear
The life of high quality is pursued, personal image also becomes more important in the daily work, or even influences whether personal income.Cause
This, common skin care item, such as face cream, the demand of facial cleanser, suncream, facial mask etc. constantly expand, cosmetics in the market
Dazzling, a large amount of cosmetics company newly creates, and people are also ready to put into high fund on cosmetics.Especially female
Property, it is huge for skin care item demand.But skin care item own care is depended merely on, cosmetic result is not satisfactory.Therefore, more
Beauty mechanism has been selected come more women that likes to be beautiful, the nursery work of skin is carried out by specialist cosmetology teacher.
However existing most beauty is essentially all that beautician by some face cleaning decontamination modes clears up human body flesh
After the dirt in dead skin and pore on skin, then the mode that skin is nursed by some nutrition skin-protection product.This is needed
Professional is wanted to operate, and operation is often very unstable, cosmetic result is also undesirable.Especially because lack operation standard,
A degree of damage can be generated to the massage of human skin by hand, face skin is made to accelerate loose and generation wrinkle etc., and
Manual operations can only also act on the surface of human skin, and be difficult to realize the deep layer nursing to skin.In order to fully send out
Wave the cosmetic result of cosmetics, it is desirable to cosmetic active ingredient, nutritional ingredient be made to penetrate into skin.Currently used promotion beauty
Ingredient realizes the ingredient of ionization using method from DC current to Cutaneous permeation, such as iontophoresis, laser photorejuvenation method etc.
The inside to be penetrated to the skin and being powered to skin.
But cosmetic result is still unobvious, but also injury can be generated to skin, therefore this problem becomes puzzlement at present
One bottleneck problem of beauty market development.Therefore it studies efficiently from infiltration cosmetics, is not only able to reduce and goes to beauty parlor
Number, and can reduce the damage to skin, reach the cosmetic result of persistent high efficiency.
Application No. is 201810004815.5 Chinese invention patents to disclose whitening and skin-protecting composition and preparation method thereof
And application.The composition includes the raw material of following parts by weight: 0.1 part~0.5 part of sodium hydroxide, 0.5 part of water~1.5 parts, lemon
0.8 part~2 parts of lemon acid, 0.5 part~1 part of octadecyl alcolol, 0.2 part~0.8 part of sodium sulfite, two split the molten spore object 10 of yeast tunning
Part~30 parts, 15 parts~43 parts of edelweiss and 12 parts~38 parts of sturgeon caviar extract.The whitening and skin-protecting of the invention combines
Object, stability is good, and viscosity is suitable for that emulsifying effectiveness is good, and lotion is fine and smooth, and nutritional properties and permeance property are good, can effectively press down
The production of melanin processed improves in vivo and superoxide dismutase obtains activity in skin epidermal cells, reinforces living radical
Elimination, prevent the generation of internal harmful substance, improve the metabolism of body, moistened using rear dermal sensation, is fine and smooth, rich in bullet
Property, without greasy and tingling sensation.But the composition is in actual use, permeability is bad, and skin absorption is limited, is unable to reach
Good cosmetic result.
Application No. is 201711056114.8 Chinese patent applications to disclose a kind of α-black bearberry of high Skin Cell infiltration
Glycoside composition and its preparation method and application.The alpha-arbutin composition includes the component of following mass content: alpha-arbutin 1.0
~15.0%, lecithin 1.0%~15.0%, quaternized soybean protein 0.4~6.0%, polyalcohol 15.0~50.0% helps cream
Agent 2.0~10.0%, the water of stabilizer 0.1~1.5% and surplus.The alpha-arbutin combination of the high Skin Cell infiltration
Object skin permeability is good, skin hold-up is high, stability is good, drugloading rate is big, can efficiently promote alpha-arbutin through skin barrier
Skin care target area is reached, whitening, freckle effect are significant.But the composition depends critically upon alpha-arbutin, due to alpha-arbutin
Preparation be not easy, it is higher to cause the composition production cost.
As it can be seen that existing cosmetics and skincare product or permeability is bad or higher cost, therefore, research and develop a kind of cost compared with
Low, good penetrability skin care item are very necessary.
Summary of the invention
For existing cosmetics and skincare product or permeability be bad or the defect of higher cost, the present invention provide one kind
From osmotrophy type cosmetics and preparation method.
First technical problem that the present invention solves is to provide a kind of preparation method from osmotrophy type cosmetics.
The present invention includes the following steps: from the preparation method of osmotrophy type cosmetics
A, it prepares condensed cream: collagen, hyaluronic acid, Propiram and Hippophae Rhamnoides L. juice being uniformly dispersed, water-setting is then added
Sol solution is concentrated into paste, loads collagen, hyaluronic acid and stablizes with hydrogel, obtains condensed cream；By weight,
2~10 parts of collagen, 5~20 parts of hyaluronic acid, 1~8 part of Propiram, 1~8 part of Hippophae Rhamnoides L. juice, 30~60 parts of hydrogel；
B, nanometer Whey protein micelles are prepared: by lactalbumin liquid by freeze-drying, high-pressure spray-drying, obtaining nano-emulsion
Protein micelles；
C, it mixes: nanometer Whey protein micelles, condensed cream, phosphatide, tristerin and jelly powder being dispersed, obtained
From osmotrophy type cosmetics；Wherein, by weight, 5~10 parts of nanometer Whey protein micelles, 20~40 parts of condensed cream,
0~20 part of phosphatidase 1,5~10 parts of tristerin, 5~10 parts of gelatin.
Skin supplement ingredient collagen, hyaluronic acid, lactalbumin, phosphatide are carried on hydrogel by the method for the present invention,
Using Hippophae Rhamnoides L. juice as permeation enhancers, promote the permeability of skin the infiltration of nutritional ingredient using Hippophae Rhamnoides L. juice, there is nutrition good
Transdermal characteristic, facilitate penetration of cuticula；Meanwhile being easy to spread in deep skin under phosphatide effect, to improve Skin Cell
Vigor；Improve blood circulation, achievees the effect that good whitening, beauty treatment, moisturizing.
Each step of the method for the present invention is described in detail below.
The purpose of a step is that condensed cream is prepared, and collagen, hyaluronic acid, Propiram and Hippophae Rhamnoides L. juice is dispersed equal
It is even, hydrogel solution is then added, is concentrated into paste, loads collagen, hyaluronic acid and stablizes with hydrogel, be concentrated
Cream.
Wherein, Propiram, that is, pulullan polysaccharide is a kind of similar caused by Aureobasidium pullulans fermentation glucan, xanthan
The extracellular water solubility cement polysaccharide of glue, the polysaccharide are by α-Isosorbide-5-Nitrae glucosides key connection maltotriose recurring unit through α -1,6 glucosides
The straight-chain polysaccharide that key is polymerized, molecular weight 20,000~2,000,000, the degree of polymerization 100~5000.There are two important spies for the polysaccharide
Property: high resilience in structure, solubility are bigger.The film forming of pulullan polysaccharide, gas barrier property, plasticity, viscosity are relatively strong, and
And there are the good characteristics such as soluble easily in water, nontoxic, colorless and odorless Propiram therefore is added in cosmetics of the invention, with
Improve skin effect.
Hippophae Rhamnoides L. juice is squeezed out by sea-buckthorn (be commonly called as vinegar willow, feel unhappy and ashamed).Containing high vitamin, ascorbic content every 100
Gram fresh fruit contains 80 to 1500 milligrams, is 5 to 8 times of Kiwi berry, and 70 times of hawthorn, 80 times of tomato, 200 times of grape.
The study found that Hippophae Rhamnoides L. juice can promote the infiltration of nutritional ingredient, therefore, the present invention, as permeation enhancers, is promoted using Hippophae Rhamnoides L. juice
The infiltration of nutritional ingredient makes nutrition have good transdermal characteristic, facilitates penetration of cuticula.Hippophae Rhamnoides L. juice of the present invention is to use
The juice that sea-buckthorn is directly squeezed out.
Hydrogel is the gel using water as decentralized medium.One is introduced in water soluble polymer with cross-linked network
Divide hydrophobic grouping and hydrophilic residue, hydrophilic residue and water molecules, hydrone is connected to netted inside, and hydrophobic residue is met
Water swellable cross-linked polymer.It is a kind of macromolecule network system, property is soft, is able to maintain certain shape, can absorb a large amount of
Water.Common hydrogel is suitable for the present invention.Preferably, in a step, the hydrogel be polyvinyl alcohol, polyethylene glycol,
One or more of sodium alginate.
Preferably, the weight concentration of hydrogel solution is 10~20%.
Preferably, the weight concentration of hydrogel solution is 16%.Inventors have found that when hydrogel solution is dense herein
When spending, the nutrition for the cosmetics being prepared is best, and effect is best.
In a step, the proportion of various components is also to influence the key of cosmetics performance.Preferably, in a step,
By weight, 8 parts of collagen, 12 parts of hyaluronic acid, 5 parts of Propiram, 4 parts of Hippophae Rhamnoides L. juice, 50 parts of hydrogel.
B step is that lactalbumin liquid is passed through freeze-drying, high-pressure fog the step of nanometer Whey protein micelles are prepared
It is dry, obtain a nanometer Whey protein micelles.
Wherein, lactalbumin is referred to as the king of albumen, is a kind of protein extracted from milk, has nutritive value
It is high, easy to digest to absorb, contain the features such as a variety of active ingredients, it is generally acknowledged one of human body good protein replenishers.The present invention
It after lactalbumin is prepared into protomere, is added in cosmetics and is uniformly dispersed, to improve the skin effect of cosmetics.
High-pressure spray-drying in b step is routine techniques, can be carried out using common high-pressure spraying equipment, without into
The special technique setting of row, it is only necessary to which the protomere after guaranteeing spray drying is nanoscale.After spray drying, nanometer is obtained
Whey protein micelles.
Preferably, in b step, the partial size of the nanometer Whey protein micelles is 100~600nm.
A step of the invention and b step have no time sequencing.A step can first be carried out, condensed cream is prepared, then carried out
A nanometer Whey protein micelles are prepared in b step；B step can also first be carried out and a nanometer Whey protein micelles are prepared,
A step is carried out again obtains condensed cream；Further, it is also possible to which a step and b step are carried out simultaneously.
The step of step c is by the mixing of various components, nanometer Whey protein micelles, condensed cream, phosphatide, stearic acid is sweet
Grease and jelly powder dispersion, obtain from osmotrophy type cosmetics.
Wherein, phosphatide is also referred to as phospholipid, Phospholipids, refers to the lipid containing phosphoric acid, belongs to complex liped.Phosphatide composition biology
The main component of film is divided into glycerophosphatide and sphingomyelins two major classes, is made of respectively glycerol and sphingol.Phosphatide is both sexes point
Son, one end are hydrophilic nitrogenous or phosphorus head, and the other end is the long hydrocarbyl chain of hydrophobic (oleophylic).Due to this, phospholipid molecule
Water-wet side is close to each other, and hydrophobic side is close to each other, and double points of rouge are often collectively formed with other molecules such as protein, glycolipid, cholesterol
Sublayer, the i.e. structure of cell membrane.Therefore, phosphatide is added in the cosmetics that the present invention uses.Under the action of phosphatide, nutritional ingredient
It is easy to spread in deep skin, to improve Skin Cell vigor, improves blood circulation, improve the skin effect of cosmetics.
Preferably, in step c, the phosphatide be egg yolk lecithin, soybean lecithin, glycerophosphonolipid, sphingolipid,
At least one of pure and mild phosphatidyl myelin of glycosphingolipid, sphingomyelin, phosphatidyl choline, phosphatidyl-4.
In step c, the proportion of each component remains the key of cosmetics performance, and the present invention has been obtained preferably by research
Proportion relation.Preferably, parts by weight meter, 6~9 parts of nanometer Whey protein micelles, 25~33 parts of condensed cream, phosphatidase 1 3~17
Part, 6~8 parts of tristerin, 6~9 parts of gelatin.
Preferably, in step c, by weight, 7 parts of nanometer Whey protein micelles, 28 parts of condensed cream, phosphatide
15 parts, 7 parts of tristerin, 8 parts of gelatin.
Second technical problem that the present invention solves is to provide a kind of from osmotrophy type cosmetics.
The present invention is from osmotrophy type cosmetics, using the above-mentioned preparation method preparation from osmotrophy type cosmetics
At.The raw material of the cosmetics is easy to get, low in cost, and good penetrability is full of nutrition, and Skin Cell vigor can be improved, and improves blood
Liquid circulation, improves whitening, beauty treatment, soothing effect.
One kind of the invention is from osmotrophy type cosmetics and preparation method, compared with prior art, prominent feature and has
Beneficial effect is:
1, skin supplement ingredient collagen, hyaluronic acid, lactalbumin, phosphatide are carried on hydrogel, with Hippophae Rhamnoides L. juice
For permeation enhancers, promote the permeability of skin the infiltration of nutritional ingredient using Hippophae Rhamnoides L. juice, make nutrition that there is good transdermal characteristic,
Facilitate penetration of cuticula.
2, it is easy to spread in deep skin under phosphatide effect, to improve Skin Cell vigor；Improve blood circulation, reaches
To good whitening, beauty treatment, moisturizing effect.
3, its method is simple, low in cost, is suitable for mass production.
Specific embodiment
In the following, the present invention will be further described in detail by way of specific embodiments, but this should not be interpreted as to the present invention
Range be only limitted to example below.Without departing from the idea of the above method of the present invention, according to ordinary skill
The various replacements or change that knowledge and customary means are made, should be included in the scope of the present invention.
Embodiment 1
One kind is prepared with the following method from osmotrophy type cosmetics, including the following steps successively carried out:
A, it prepares condensed cream: collagen, hyaluronic acid, Propiram and Hippophae Rhamnoides L. juice being uniformly dispersed, water-setting is then added
Sol solution is displayed and is concentrated into paste for 24 hours, and condensed cream is obtained；By weight, 2 parts of collagen, 20 parts of hyaluronic acid, Pu Lu
It is 1 part, 1 part of Hippophae Rhamnoides L. juice, 30 parts of hydrogel blue；The hydrogel is polyvinyl alcohol；The weight concentration of hydrogel solution is 10%.
B, nanometer Whey protein micelles are prepared: by lactalbumin liquid by freeze-drying, high-pressure spray-drying, obtaining nano-emulsion
Protein micelles；The partial size of the nanometer Whey protein micelles is between 100~600nm.
C, it mixes: nanometer Whey protein micelles, condensed cream, phosphatide, tristerin and jelly powder being dispersed, obtained
From osmotrophy type cosmetics；Wherein, by weight, 5 parts of nanometer Whey protein micelles, 20 parts of condensed cream, 0 part of phosphatidase 2,
5 parts of tristerin, 5 parts of gelatin.Wherein, the phosphatide is egg yolk lecithin.
Embodiment 2
One kind is prepared with the following method from osmotrophy type cosmetics, including the following steps successively carried out:
A, nanometer Whey protein micelles are prepared: by lactalbumin liquid by freeze-drying, high-pressure spray-drying, obtaining nano-emulsion
Protein micelles；The partial size of the nanometer Whey protein micelles is between 100~600nm.
B, it prepares condensed cream: collagen, hyaluronic acid, Propiram and Hippophae Rhamnoides L. juice being uniformly dispersed, water-setting is then added
Sol solution is displayed and is concentrated into paste for 24 hours, and condensed cream is obtained；By weight, 10 parts of collagen, 5 parts of hyaluronic acid, Pu Lu
It is 8 parts, 8 parts of Hippophae Rhamnoides L. juice, 60 parts of hydrogel blue；The hydrogel is polyethylene glycol；The weight concentration of hydrogel solution is 20%.
C, it mixes: nanometer Whey protein micelles, condensed cream, phosphatide, tristerin and jelly powder being dispersed, obtained
From osmotrophy type cosmetics；Wherein, by weight, 10 parts of nanometer Whey protein micelles, 40 parts of condensed cream, phosphatidase 10
Part, 10 parts of tristerin, 10 parts of gelatin.Wherein, the phosphatide is soybean lecithin.
Embodiment 3
One kind is prepared with the following method from osmotrophy type cosmetics, including the following steps successively carried out:
A, it prepares condensed cream: collagen, hyaluronic acid, Propiram and Hippophae Rhamnoides L. juice being uniformly dispersed, water-setting is then added
Sol solution is displayed and is concentrated into paste for 24 hours, and condensed cream is obtained；By weight, 4 parts of collagen, 18 parts of hyaluronic acid, Pu Lu
It is 5 parts, 4 parts of Hippophae Rhamnoides L. juice, 40 parts of hydrogel blue；The hydrogel is sodium alginate；The weight concentration of hydrogel solution is 12%.
B, nanometer Whey protein micelles are prepared: by lactalbumin liquid by freeze-drying, high-pressure spray-drying, obtaining nano-emulsion
Protein micelles；The partial size of the nanometer Whey protein micelles is between 100~600nm.
C, it mixes: nanometer Whey protein micelles, condensed cream, phosphatide, tristerin and jelly powder being dispersed, obtained
From osmotrophy type cosmetics；Wherein, by weight, 6 parts of nanometer Whey protein micelles, 33 parts of condensed cream, 3 parts of phosphatidase 1,
6 parts of tristerin, 9 parts of gelatin.Wherein, the phosphatide is phosphatidylinositols.
Embodiment 4
One kind is prepared with the following method from osmotrophy type cosmetics, including the following steps successively carried out:
A, it prepares condensed cream: collagen, hyaluronic acid, Propiram and Hippophae Rhamnoides L. juice being uniformly dispersed, water-setting is then added
Sol solution is displayed and is concentrated into paste for 24 hours, and condensed cream is obtained；By weight, 8 parts of collagen, 15 parts of hyaluronic acid, Pu Lu
It is 7 parts, 6 parts of Hippophae Rhamnoides L. juice, 50 parts of hydrogel blue；The hydrogel is sodium alginate；The weight concentration of hydrogel solution is 15%.
B, nanometer Whey protein micelles are prepared: by lactalbumin liquid by freeze-drying, high-pressure spray-drying, obtaining nano-emulsion
Protein micelles；The partial size of the nanometer Whey protein micelles is between 100~600nm.
C, it mixes: nanometer Whey protein micelles, condensed cream, phosphatide, tristerin and jelly powder being dispersed, obtained
From osmotrophy type cosmetics；Wherein, by weight, 9 parts of nanometer Whey protein micelles, 25 parts of condensed cream, 7 parts of phosphatidase 1,
8 parts of tristerin, 6 parts of gelatin.Wherein, the phosphatide is phosphatidyl choline.
Embodiment 5
One kind is prepared with the following method from osmotrophy type cosmetics, including the following steps successively carried out:
A, it prepares condensed cream: collagen, hyaluronic acid, Propiram and Hippophae Rhamnoides L. juice being uniformly dispersed, water-setting is then added
Sol solution is displayed and is concentrated into paste for 24 hours, and condensed cream is obtained；By weight, 8 parts of collagen, 12 parts of hyaluronic acid, Pu Lu
It is 5 parts, 4 parts of Hippophae Rhamnoides L. juice, 50 parts of hydrogel blue；The hydrogel is sodium alginate；The weight concentration of hydrogel solution is 16%.
B, nanometer Whey protein micelles are prepared: by lactalbumin liquid by freeze-drying, high-pressure spray-drying, obtaining nano-emulsion
Protein micelles；The partial size of the nanometer Whey protein micelles is between 100~600nm.
C, it mixes: nanometer Whey protein micelles, condensed cream, phosphatide, tristerin and jelly powder being dispersed, obtained
From osmotrophy type cosmetics；Wherein, by weight, 8 parts of nanometer Whey protein micelles, 30 parts of condensed cream, 5 parts of phosphatidase 1,
7 parts of tristerin, 7 parts of gelatin.Wherein, the phosphatide is glycerophosphonolipid.
Embodiment 6
One kind is prepared with the following method from osmotrophy type cosmetics, including the following steps successively carried out:
A, it prepares condensed cream: collagen, hyaluronic acid, Propiram and Hippophae Rhamnoides L. juice being uniformly dispersed, water-setting is then added
Sol solution is displayed and is concentrated into paste for 24 hours, and condensed cream is obtained；By weight, 8 parts of collagen, 12 parts of hyaluronic acid, Pu Lu
It is 5 parts, 4 parts of Hippophae Rhamnoides L. juice, 50 parts of hydrogel blue；The hydrogel is sodium alginate；The weight concentration of hydrogel solution is 16%.
B, nanometer Whey protein micelles are prepared: by lactalbumin liquid by freeze-drying, high-pressure spray-drying, obtaining nano-emulsion
Protein micelles；The partial size of the nanometer Whey protein micelles is between 100~600nm.
C, it mixes: nanometer Whey protein micelles, condensed cream, phosphatide, tristerin and jelly powder being dispersed, obtained
From osmotrophy type cosmetics；Wherein, by weight, 7 parts of nanometer Whey protein micelles, 28 parts of condensed cream, 5 parts of phosphatidase 1,
7 parts of tristerin, 8 parts of gelatin.Wherein, the phosphatide is egg yolk lecithin.
Comparative example 1
A, it prepares condensed cream: collagen, hyaluronic acid, Propiram is uniformly dispersed, hydrogel solution is then added, it is old
It puts and is concentrated into paste for 24 hours, obtain condensed cream；By weight, 8 parts of collagen, 12 parts of hyaluronic acid, 5 parts of Propiram, water-setting
50 parts of glue；The hydrogel is sodium alginate；The weight concentration of hydrogel solution is 16%.
B, nanometer Whey protein micelles are prepared: by lactalbumin liquid by freeze-drying, high-pressure spray-drying, obtaining nano-emulsion
Protein micelles；The partial size of the nanometer Whey protein micelles is between 100~600nm.
C, it mixes: nanometer Whey protein micelles, condensed cream, phosphatide, tristerin and jelly powder being dispersed, obtained
From osmotrophy type cosmetics；Wherein, by weight, 7 parts of nanometer Whey protein micelles, 28 parts of condensed cream, 5 parts of phosphatidase 1,
7 parts of tristerin, 8 parts of gelatin.Wherein, the phosphatide is egg yolk lecithin.
Hippophae Rhamnoides L. juice is not used in comparative example 1.
Comparative example 2
A, it prepares condensed cream: collagen, hyaluronic acid, Propiram and Hippophae Rhamnoides L. juice being uniformly dispersed, water-setting is then added
Sol solution is displayed and is concentrated into paste for 24 hours, and condensed cream is obtained；By weight, 8 parts of collagen, 12 parts of hyaluronic acid, Pu Lu
It is 5 parts, 4 parts of Hippophae Rhamnoides L. juice, 50 parts of hydrogel blue；The hydrogel is sodium alginate；The weight concentration of hydrogel solution is 16%.
B, nanometer Whey protein micelles are prepared: by lactalbumin liquid by freeze-drying, high-pressure spray-drying, obtaining nano-emulsion
Protein micelles；The partial size of the nanometer Whey protein micelles is between 100~600nm.
C, it mixes: nanometer Whey protein micelles, condensed cream, tristerin and jelly powder is dispersed, obtain seeping certainly
Saturating auxotype cosmetics；Wherein, by weight, 7 parts of nanometer Whey protein micelles, 28 parts of condensed cream, tristerin 7
Part, 8 parts of gelatin.
Phosphatide is not used in comparative example 2.
Above-described embodiment 1~6 and the product of comparative example 1~2 are subjected to permeance property test, the result is shown in tables 1.Specifically
Test method are as follows: take the crystal soil that partial size is about 2mm as trial target, first measurement primary particles partial size d1, then set respectively
It in above-described embodiment 1~6 and the product of comparative example 1~2, is taken out after 15min, observes the degrees of expansion of crystal soil, measurement
Grain partial size d2, then crystal soil expansion multiple characterizes product osmotic effect than (d2/d1) with the variation of partial size.
Table 1
| Number | Crystal soil expansion multiple (again) |
| Embodiment 1 | 2.4 |
| Embodiment 2 | 2.5 |
| Embodiment 3 | 2.7 |
| Embodiment 4 | 2.6 |
| Embodiment 5 | 2.8 |
| Embodiment 6 | 3.0 |
| Comparative example 1 | 1.4 |
| Comparative example 2 | 2.5 |
Above-described embodiment 1~6 and the product of comparative example 1~2 are subjected to skin using test, and to before and after skin use into
The test such as row skin moisture, elasticity, dermatoglyph, the result is shown in tables 2.Specific test mode is as follows:
Test crowd: the 800 20-40 years old women selected at random；Every set product tests 100 people；
Test equipment: German DJM skinanalysis apparatus；
Test specification: to the hand inner forearm same position of each tester carry out skin moisture, skin temperature, elasticity,
Dermatoglyph test, measures initial value respectively, then smears same amount using cosmetics opponent's inner forearm of the invention,
Skin moisture, elasticity and dermatoglyph situation are tested after 10min, is hereafter smeared 1 time respectively sooner or later daily, and test uses 7 days
Skin moisture, elasticity, dermatoglyph situation, and the data of 100 people are averaged.
Table 2
Claims (10)
1. a kind of preparation method from osmotrophy type cosmetics, which comprises the steps of:
A, it prepares condensed cream: collagen, hyaluronic acid, Propiram and Hippophae Rhamnoides L. juice is uniformly dispersed, water-setting peptization is then added
Liquid is concentrated into paste, obtains condensed cream；By weight, 2~10 parts of collagen, 5~20 parts of hyaluronic acid, Propiram 1~
8 parts, 1~8 part of Hippophae Rhamnoides L. juice, 30~60 parts of hydrogel；
B, nanometer Whey protein micelles are prepared: by lactalbumin liquid by freeze-drying, high-pressure spray-drying, obtaining a nanometer whey egg
White protomere；
C, it mixes: nanometer Whey protein micelles, condensed cream, phosphatide, tristerin and jelly powder is dispersed, obtain seeping certainly
Saturating auxotype cosmetics；Wherein, by weight, 5~10 parts of nanometer Whey protein micelles, 20~40 parts of condensed cream, phosphatide
10~20 parts, 5~10 parts of tristerin, 5~10 parts of gelatin.
2. the preparation method according to claim 1 from osmotrophy type cosmetics, it is characterised in that: described in a step
Hydrogel is one or more of polyvinyl alcohol, polyethylene glycol, sodium alginate.
3. the preparation method according to claim 1 from osmotrophy type cosmetics, it is characterised in that: in a step, water-setting
The weight concentration of sol solution is 10~20%.
4. the preparation method according to claim 3 from osmotrophy type cosmetics, it is characterised in that: in a step, water-setting
The weight concentration of sol solution is 16%.
5. the preparation method according to claim 1 from osmotrophy type cosmetics, it is characterised in that: in a step, by weight
It measures part to count, 8 parts of collagen, 12 parts of hyaluronic acid, 5 parts of Propiram, 4 parts of Hippophae Rhamnoides L. juice, 50 parts of hydrogel.
6. the preparation method according to claim 1 from osmotrophy type cosmetics, it is characterised in that: described in b step
The partial size of nanometer Whey protein micelles is 100~600nm.
7. the preparation method according to claim 1 from osmotrophy type cosmetics, it is characterised in that: described in step c
Phosphatide is egg yolk lecithin, soybean lecithin, glycerophosphonolipid, sphingolipid, glycosphingolipid, sphingomyelin, phosphatidyl
At least one of pure and mild phosphatidyl myelin of choline, phosphatidyl-4.
8. the preparation method according to claim 1 from osmotrophy type cosmetics, it is characterised in that: in step c, by weight
It measures part to count, 6~9 parts of nanometer Whey protein micelles, 25~33 parts of condensed cream, 3~17 parts of phosphatidase 1, tristerin 6~8
Part, 6~9 parts of gelatin.
9. the preparation method according to claim 8 from osmotrophy type cosmetics, it is characterised in that: in step c, by weight
It measures part to count, 7 parts of nanometer Whey protein micelles, 28 parts of condensed cream, 5 parts of phosphatidase 1,7 parts of tristerin, 8 parts of gelatin.
10. a kind of from osmotrophy type cosmetics, it is characterised in that: using according to any one of claims 1 to 9 from infiltration battalion
The preparation method for supporting type cosmetics is prepared.
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