CN118767041A - Traditional Chinese medicine composition for treating qi-yin deficiency type chronic fatigue syndrome and application thereof - Google Patents
Traditional Chinese medicine composition for treating qi-yin deficiency type chronic fatigue syndrome and application thereof Download PDFInfo
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Abstract
The invention discloses a traditional Chinese medicine composition for treating qi-yin deficiency type chronic fatigue syndrome and application thereof, and belongs to the technical field of traditional Chinese medicines. The traditional Chinese medicine composition comprises the following raw materials: 5-10g of ginseng, 5-15g of raw astragalus, 3-6g of cinnamon, 5-10g of angelica, 5-10g of white paeony root, 5-15g of kudzuvine root, 5-10g of wine sealwort, 5-12g of hairyvein agrimony, 5-10g of dwarf lilyturf tuber, 9-15g of raw dragon bone, 9-15g of raw oyster, 5-10g of silktree albizia flower, 10-20g of fried spina date seed, 5-10g of poria with hostwood, 5-10g of poria cocos, 5-10g of achyranthes root and 3-6g of honey-fried licorice root. The traditional Chinese medicine composition has strict compatibility and reasonable formula, and clinical experiments prove that the traditional Chinese medicine composition has remarkable treatment effect on chronic fatigue syndrome, especially qi-yin deficiency type fatigue, and is worthy of clinical popularization and application.
Description
Technical Field
The invention relates to the technical field of traditional Chinese medicines, in particular to a traditional Chinese medicine composition for treating qi-yin deficiency type chronic fatigue syndrome and application thereof.
Background
Chronic fatigue syndrome (Chronic Fatigue Syndrome, CFS) is a group of multiple systemic disease syndromes that appear under high-rhythm, fast-living, strong pressure in contemporary society and are mainly manifested by long-term fatigue. Its clinical manifestation is mainly represented by hypofunction and fatigue in the nervous system, motor system, digestive system, urinary system and sensory system of organism. It is a basic feature that it is extremely low for a long time and can not be relieved after rest, and each examination has no related organic lesions. The incidence rate of CFS is higher, women are more, the trend of increasing year by year, reducing the age and high school is presented, the normal work is seriously influenced, the quality of life is reduced, immeasurable loss is brought to the health of individuals, the happiness of families and the development of society, and the problem to be solved in the current society is urgent. Its pathogenesis is very complex and is the result of the combined action of various factors including heredity, environment, infection, immune and nerve dysfunction, and the viral infection in recent years is one of the main factors causing chronic fatigue syndrome, such as novel coronavirus, norovirus, herpesvirus, etc. Chronic fatigue syndrome is mainly manifested by fatigue, with short-term hypomnesis or inadequacy, physical discomfort after mental work, sleep disorder and depression, and other somatic and mental nerve symptoms, especially fatigue and sleep disorder.
Even though there is no disease name of chronic fatigue syndrome in the traditional Chinese medicine, there is a great deal of description in ancient books about the symptom of fatigue. The "fatigue" related terms described in Huangdi's interior meridian are up to tens of, such as "resolution of the alpha", "transverse resolution", "stricken thin", "idle", "relaxing", "restless limbs", "straying" and so on. It is recorded in Jing Yue quan Shu and Xuan Sheng Ji (deficiency of the whole book), that the actions are barely known, but the actions should be regarded as delusions, all causing damage. "Huangdi's internal channel Su-Xuan five-qi Chan Zhi" points out: "impairment of blood due to chronic visual injury, impairment of qi due to chronic lying down, impairment of meat due to chronic sitting down, impairment of bone due to chronic running down", impairment of tendons due to overfatigue ". The "doctor four-purpose pathogenesis treatises" also indicates: the "the heart of the heart is exercised by the heart consider, the liver is exercised by the unexpected thinking, the spleen is exercised by the premenstrual matter, the lung is exercised by the worry, and the kidney is exercised by the erotic sexual desire excess". The viral infection belongs to the exogenous pathogenic factors, and six pathogenic factors can lead to the dysfunction of five zang organs, such as deficiency and impairment of one disease in the "not resident Ji" of Qing Dynasty Wu Cheng, which is not only caused by internal injury, but also common in exogenous six pathogenic factors, which are not solely caused by pathogenic wind, and six pathogenic factors can lead to overstrain. The pathogenesis of the disease is that the disease is related to a plurality of viscera and systems, and the disease is that the disease is deficient and excessive and the deficiency and excessive are mixed, so the pathogenesis can be summarized as viscera deficiency and loss, and the disease has low self-function and is fatigue.
The current western medicine treatment mainly supports symptomatic support, has the therapies of immunity, antidepressant, antivirus, sedative hypnotic, large-dose vitamin and other nutrition supplements, only can relieve partial clinical symptoms, has certain toxic and side effects, is easy to repeat and can not achieve effective improvement. The traditional Chinese medicine composition for treating the qi-yin deficiency type chronic fatigue syndrome has unique advantages, and provides a novel strategy for treating the qi-yin deficiency type chronic fatigue syndrome.
Disclosure of Invention
The invention aims to provide a traditional Chinese medicine composition for treating qi-yin deficiency type chronic fatigue syndrome and application thereof, so as to solve the problems in the prior art. The traditional Chinese medicine composition disclosed by the invention is combined with the medicines, takes qi and blood tonifying as a synopsis, and also has the effects of calming heart and soothing the nerves, greatly tonifying primordial qi without helping fire, ascending clear yang and descending turbid yin, strengthening the root and banking up primordial qi, and is strictly compatible, so that the traditional Chinese medicine composition has a reasonable formula, has a remarkable treatment effect on chronic fatigue syndrome, especially qi-yin deficiency type fatigue, and is worthy of clinical popularization and application.
In order to achieve the above object, the present invention provides the following solutions:
The invention provides a traditional Chinese medicine composition for treating qi-yin deficiency type chronic fatigue syndrome, which comprises the following raw materials: 5-10g of ginseng, 5-15g of raw astragalus, 3-6g of cinnamon, 5-10g of angelica, 5-10g of white paeony root, 5-15g of kudzuvine root, 5-10g of wine sealwort, 5-12g of hairyvein agrimony, 5-10g of dwarf lilyturf tuber, 9-15g of raw dragon bone, 9-15g of raw oyster, 5-10g of silktree albizia flower, 10-20g of fried spina date seed, 5-10g of poria with hostwood, 5-10g of poria cocos, 5-10g of achyranthes root and 3-6g of honey-fried licorice root. .
Further, the preparation method comprises the following raw materials: 6g of ginseng, 15g of raw astragalus, 3g of cinnamon, 10g of angelica, 10g of white peony root, 12g of kudzuvine root, 10g of rhizoma polygonati preparata, 12g of hairyvein agrimony, 10g of dwarf lilyturf tuber, 15g of raw dragon bone, 15g of raw oyster, 10g of albizia flower, 20g of fried spina date seed, 10g of poria with hostwood, 10g of poria cocos, 10g of achyranthes root and 6g of honey-fried licorice root.
The invention also provides a traditional Chinese medicine preparation for treating the qi-yin deficiency type chronic fatigue syndrome, and the effective components of the traditional Chinese medicine preparation are the traditional Chinese medicine composition.
Further comprises a carrier and auxiliary materials which are acceptable in the pharmacy.
The invention also provides the application of the traditional Chinese medicine composition or the traditional Chinese medicine preparation in preparing a medicine for treating qi-yin deficiency type chronic fatigue syndrome.
Further, the dosage form of the medicament comprises granules.
Further, methods of administration of the medicament include oral and parenteral administration.
The fatigue syndrome is diagnosed as 'consumptive disease', the cause of the consumptive disease is mainly considered to be two factors of congenital and acquired by the Chinese medicine, and the patient with the consumptive disease in young age usually takes congenital as the main cause; the general cause of the consumptive disease is the later days of the adult. Such as congenital weakness, acquired disease factors, overfatigue, improper diet, etc., can cause deficiency of qi, blood, yin and yang of viscera and can not be recovered for a long time. Therefore, the chronic fatigue syndrome is characterized by the pathological changes of the spleen and kidney, which are related to the exogenous environment. The south of the Ling area belongs to the subtropical monsoon marine climate type, the crowd is characterized by mainly middle-aged and young people, fast rhythm and high life mental pressure, the chronic fatigue syndrome in the area is usually caused by deficiency of both qi and yin, qi deficiency can not warm food essence, and yin deficiency can cause the disease that the joints of limbs are clear and lose nourishment. The traditional Chinese medicine composition formula (the particles for resisting the mental fatigue) starts from the traditional Chinese medicine integral dialectical theory and adjusts the viscera functions, thereby achieving the purpose and effect of treatment. Through years of clinical application and experience summarization, attention is paid to the coordination of qi and blood of the mind and body for the patients. Taking qi and yin nourishing, body resistance strengthening and principal consolidating as a general rule, and also calming and tranquillizing, the recipe can greatly tonify primordial qi without helping fire, nourish yin and eliminate pathogenic factors without generating dampness, raise clear yang and reduce turbid yin, consolidate principal qi and strengthen primordial qi sufficiently, and can promote sleep and self-relieve fatigue.
The traditional Chinese medicine composition takes ginseng, astragalus and cinnamon as monarch agents, and the ginseng can tonify primordial qi and tonify deficiency of five viscera. Sheng Huang Qi can tonify qi, promote qi flow and strengthen superficies. It can not only tonify qi of lung and spleen, but also raise yang and strengthen superficies, so it is combined with ren Shen to strengthen the actions of tonifying qi and consolidating primordial qi. Cinnamon is combined, which is to take the effect of warming and activating blood vessels, so that it can induce other drugs into blood system, warm kidney and strengthen yang, as described in "ancient and modern medical prescriptions": the ginseng and astragalus root are not led by cassia twig, can not be singly used, and the three medicines are combined together to play the roles of tonifying qi, warming yang and activating blood vessels. Ministerial wine, rhizoma Polygonati, nourishing yin qi of lung, spleen and kidney, and the interior channel of Huangdi: forty years and yin qi is from half, so that the special yellow essence nourishes yin qi, has mild wine property, does not obstruct spleen and stomach, prosecutes ginseng, astragalus, cassia Wen Yangyang qi, and the wine rhizoma polygonati and the dwarf lilyturf tuber are matched to nourish yin qi, tonify qi and promote the production of body fluid, so that yin and yang qi are both complemented, and the dryness of ginseng, astragalus and cassia can be adjunctively achieved; radix Ophiopogonis is matched with Ginseng radix to get the idea of activating pulse; the agrimony is also named as Deli grass, and the main medicine of the 'Sanxian decoction' which is a good prescription for strengthening the body resistance and tonifying deficiency and is created by the famous doctors and the ancestors is the agrimony. Dang Gui is combined with Bai Shao, so it also has the effect of nourishing yin and blood and combining with sound and movement. Poria with Poria has effects of tranquilizing mind, invigorating spleen, eliminating dampness, and Ginseng radix has effects of nourishing primordial qi of lower jiao, purging fire in kidney, nourishing yin, eliminating pathogenic factors, and promoting no generation of dampness. With the assistance of the albizia flower for resolving depression and tranquillizing, the stir-fried spina date seed for nourishing blood and tranquillizing, the effects of protecting spirit, nourishing heart and tranquillizing are achieved, the sleep is safe, the primordial qi is sufficient, and the fatigue is self-eliminated. The raw keels and the raw oysters can submerge yang qi, protect primordial qi, and consolidate the exterior of the astragalus, so that the raw keels and the raw oysters can not excessively dissipate, and can also consolidate nutrient and defensive qi, so that the vital qi is stored in the body, and pathogenic factors cannot be dried. The honey-fried licorice root not only assists the ginseng and astragalus root in tonifying qi, reinforcing spleen and regulating middle warmer, but also harmonizes the medicines. Pueraria root, radix Puerariae, has the actions of promoting the production of body fluid and moistening dryness, and nourishing yin. Niu xi has the actions of inducing fire to descend and combining with Pu Gou jin to promote clear yang and descend turbid qi, and combining with Rou Gui to promote warm yang and blood circulation to promote blood circulation.
The invention discloses the following technical effects:
The traditional Chinese medicine composition disclosed by the invention is used for all the medicines together, takes qi and yin tonifying, body resistance strengthening and principal strengthening as a general rule, and also has the effects of calming the heart and soothing the nerves, the traditional Chinese medicine composition is capable of greatly tonifying primordial qi without helping fire, nourishing yin and eliminating pathogenic factors without generating dampness, ascending clear yang and descending turbid yin, strengthening principal and banking up primordial qi, and is effective in treating etiology and pathogenesis of qi-yin deficiency type chronic fatigue syndrome, and is strict in compatibility and reasonable in formula. Clinical experiments prove that the traditional Chinese medicine composition provided by the invention can relieve symptoms of chronic fatigue syndrome, especially fatigue patients after virus infection such as hypodynamia, somnolence, dizziness and the like, and has the effects of tonifying qi, raising yang, tonifying qi and strengthening exterior; after 3 months of follow-up investigation, the long-term effect is found to be obvious, and the method is worthy of clinical popularization and application.
Detailed Description
Various exemplary embodiments of the invention will now be described in detail, which should not be considered as limiting the invention, but rather as more detailed descriptions of certain aspects, features and embodiments of the invention.
It is to be understood that the terminology used herein is for the purpose of describing particular embodiments only and is not intended to be limiting of the invention. In addition, for numerical ranges in this disclosure, it is understood that each intermediate value between the upper and lower limits of the ranges is also specifically disclosed. Every smaller range between any stated value or stated range, and any other stated value or intermediate value within the stated range, is also encompassed within the invention. The upper and lower limits of these smaller ranges may independently be included or excluded in the range.
Unless otherwise defined, all technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the art to which this invention belongs. Although only preferred methods and materials are described herein, any methods and materials similar or equivalent to those described herein can be used in the practice or testing of the present invention. All documents mentioned in this specification are incorporated by reference for the purpose of disclosing and describing the methods and/or materials associated with the documents. In case of conflict with any incorporated document, the present specification will control.
It will be apparent to those skilled in the art that various modifications and variations can be made in the specific embodiments of the invention described herein without departing from the scope or spirit of the invention. Other embodiments will be apparent to those skilled in the art from consideration of the specification of the present invention. The specification and examples of the present invention are exemplary only.
As used herein, the terms "comprising," "including," "having," "containing," and the like are intended to be inclusive and mean an inclusion, but not limited to.
The experimental methods in the following examples, unless otherwise specified, are conventional methods, and are carried out according to techniques or conditions described in the literature in the field or according to the product specifications. Materials, reagents and the like used in the examples described below are commercially available unless otherwise specified.
Example 1
A traditional Chinese medicine granule for treating qi-yin deficiency type chronic fatigue syndrome comprises the following raw materials in parts by weight:
6g of ginseng, 15g of raw astragalus, 3g of cinnamon, 10g of angelica, 10g of white peony root, 12g of kudzuvine root, 10g of rhizoma polygonati preparata, 12g of hairyvein agrimony, 10g of dwarf lilyturf tuber, 15g of raw dragon bone, 15g of raw oyster, 10g of albizia flower, 20g of fried spina date seed, 10g of poria with hostwood, 10g of poria cocos, 10g of achyranthes root and 6g of honey-fried licorice root.
The preparation method comprises the following steps: the preparation method of the traditional Chinese medicine granule adopts the existing conventional granule preparation method, and is as follows:
Mixing the above medicinal materials, decocting with water, each time with water amount of 8 times of the weight of the medicinal materials, decocting for 1 hr each time, mixing the decoctions, and concentrating under reduced pressure to obtain concentrated solution;
adding absolute ethyl alcohol to the concentrated solution until the ethanol content is 60vol%, standing, filtering to obtain filtrate, removing ethanol in the filtrate, and concentrating under reduced pressure to obtain thick paste;
Mixing the thick paste with dextrin (adjuvant) according to a weight ratio of 10:1, uniformly mixing, drying and granulating to obtain the traditional Chinese medicine granule for treating the chronic fatigue syndrome of deficiency of both qi and yin.
The traditional Chinese medicine granules are packaged according to 10 g/bag and named as the particles for protecting spirit and relieving fatigue.
Example 2
A traditional Chinese medicine granule for treating qi-yin deficiency type chronic fatigue syndrome comprises the following raw materials in parts by weight:
5g of ginseng, 5g of raw astragalus, 3g of cinnamon, 5g of angelica, 5g of white peony root, 5g of kudzuvine root, 5g of rhizoma polygonati preparata, 5g of hairyvein agrimony, 5g of dwarf lilyturf tuber, 9g of raw dragon bone, 9g of raw oyster, 5g of albizia flower, 10g of fried spina date seed, 5g of poria with hostwood, 5g of poria cocos, 5g of achyranthes root and 3g of honey-fried licorice root.
The preparation method is the same as in example 1.
Example 3
A traditional Chinese medicine granule for treating qi-yin deficiency type chronic fatigue syndrome comprises the following raw materials in parts by weight:
10g of ginseng, 15g of raw astragalus, 6g of cinnamon, 10g of angelica, 10g of white peony root, 15g of kudzuvine root, 10g of rhizoma polygonati preparata, 12g of hairyvein agrimony, 10g of dwarf lilyturf tuber, 15g of raw dragon bone, 15g of raw oyster, 10g of albizia flower, 20g of fried spina date seed, 10g of poria with hostwood, 10g of poria cocos, 10g of achyranthes root and 6g of honey-fried licorice root.
The preparation method is the same as in example 1.
Comparative example 1
A traditional Chinese medicine granule for treating qi-yin deficiency type chronic fatigue syndrome comprises the following raw materials in parts by weight:
6g of ginseng, 15g of raw astragalus, 3g of white peony root, 10g of Chinese angelica, 10g of cinnamon, 12g of kudzuvine root, 10g of rhizoma polygonati preparata, 12g of hairyvein agrimony, 10g of dwarf lilyturf tuber, 15g of raw dragon bone, 15g of raw oyster, 10g of albizia flower, 20g of fried spina date seed, 10g of poria with hostwood, 10g of poria cocos, 10g of achyranthes root and 6g of honey-fried licorice root.
The preparation method is the same as in example 1.
Comparative example 2
A traditional Chinese medicine granule for treating qi-yin deficiency type chronic fatigue syndrome comprises the following raw materials in parts by weight:
6g of ginseng, 15g of raw astragalus, 3g of cinnamon, 10g of angelica, 10g of white peony root, 12g of kudzuvine root, 10g of rhizoma polygonati preparata, 12g of hairyvein agrimony, 10g of dwarf lilyturf tuber, 15g of oriental waterplantain rhizome, 15g of peach seed, 15g of safflower, 15g of root of red-rooted salvia, 10g of poria with hostwood, 10g of poria cocos, 10g of achyranthes root and 6g of honey-fried licorice root.
The preparation method is the same as in example 1.
Effect example
1 Effect verification
1.1 Experimental methods
The present invention study was made with reference to the diagnostic criteria set by the U.S. center for disease control (Centers for Disease Control, CDC) 1994: patients have clinically rated, unexplained, persistent or recurrent chronic fatigue symptoms that are new or have a definite onset (e.g., not life-long), are not a result of sustained exertion, do not get sufficiently relieved upon rest, and have resulted in significantly reduced levels of work, education, society or personal activity than before; the following symptoms occur simultaneously in 4 or more than 4, and these symptoms have persisted or repeatedly developed for 3 months or more: (1) Discomfort after exertion (general uncomfortable or restless sensation, a non-specific sensation, often a precursor to sensation or other disease) is greater than 24 hours; (2) sleep incapable of being impaired; (3) severe short-term memory or attention deficit disorder; (4) A new type, pattern or severity of headache; (5) muscle pain; (6) polyarthritis pain without joint redness and swelling.
Patients meeting the 'qi-yin deficiency type fatigue syndrome' are selected, and total of 324 patients are selected. Randomly divided into 3 groups: example 1 group, comparative example 1 group and comparative example 2 group. Example 1 group was treated by taking the traditional Chinese medicine granule of example 1, comparative example 1 group was treated by taking the traditional Chinese medicine granule of comparative example 1, and comparative example 2 group was treated by taking the traditional Chinese medicine granule of comparative example 2. The administration method comprises the following steps: taken twice a day, one bag at a time after meals, and the treatment course is 4 weeks.
1.2 Observations index
Fatigue symptom sign score, fatigue Severity Scale (FSS), qi deficiency syndrome score, meridian detection in traditional Chinese medicine.
1.3 Efficacy evaluation criteria
According to the traditional Chinese medicine syndrome and symptom curative effect evaluation standard: and judging the curative effect of the total scores of the Chinese medicine syndromes and the scores of the symptoms, and referring to the guidelines of clinical research of new Chinese medicine.
① And (3) healing: the clinical symptoms of the traditional Chinese medicine disappear or the basal wood disappears, and n is more than or equal to 95%;
② The effect is shown: the clinical symptoms and physical signs of the traditional Chinese medicine are obviously improved, and n is more than or equal to 70% and less than 95%;
③ The method is effective: the clinical symptoms and physical signs of the traditional Chinese medicine are improved, and n is more than or equal to 30% and less than 70%;
④ Invalidation: the clinical symptoms and physical signs of the traditional Chinese medicine are not obviously improved or even aggravated, and n is less than 30 percent.
1.4 Total efficacy criterion
Significant efficiency= (number of recovery cases in this group + number of significant effects in this group)/number of total cases in this group x 100%.
Effective rate = (number of recovery cases in this group + number of significant cases in this group + number of effective cases in this group)/total number of cases in this group x 100%.
Total effective rate = significant rate + effective rate.
The experimental results are shown in table 1:
Table 1 curative effects of each group
| Group of | Has obvious effect | Effective and effective | Invalidation of | Total effective rate (%) | Inefficiency (%) |
| Example 1 group | 11 | 75 | 22 | 79.63 | 20.37 |
| Comparative example 1 group | 5 | 64 | 39 | 63.89 | 36.11 |
| Comparative example 2 group | 0 | 59 | 49 | 54.63 | 45.37 |
From the above experimental results, it can be seen that: the total effective rate of example 1 set reached 79% or more, the inefficiency was less than 21%, while the total effective rates of comparative examples 1-2 were all 64% or less, which is significantly different from example 1 set. Therefore, the traditional Chinese medicine composition provided by the invention can treat qi-yin deficiency type chronic fatigue syndrome and has a remarkable treatment effect.
1.5 Long-term Effect investigation
The patients in the group of example 1 were subjected to a follow-up survey for 3 months, the total number of follow-up was 86, 56 patients did not see significant recurrence, 26 patients had slight recurrence, and 4 patients had severe recurrence. The traditional Chinese medicine composition for treating the qi-yin deficiency type chronic fatigue syndrome has obvious long-term effect and is worthy of clinical popularization and application.
2. Typical cases
Case one: chronic fatigue of a male in 2022, after 12 months of deficiency of both qi and yin, has been 4 months, often diarrhea, 6-7 times/day, gastralgia and diarrhea after eating cold and cool food, flatulence, distention, belching, aversion to cold, aversion to wind, waiting for urination, sleep and anorexia. After the granule prescription for resisting spirit and relieving fatigue is taken for 4 weeks, the energy is improved, the fatigue is improved, the stool is better, and the stool is performed for 1-2 times a day.
Case two: some women, after qi and yin deficiency, the body is heavy and fatigued for 3 months, the limbs are weak, the memory is obviously reduced, the chloasma is increased, the menstruation amount is small, the sleeping is shallow and easy to wake up, and the dreaminess is realized. After the granule prescription for resisting spirit and relieving fatigue is taken for 4 weeks, fatigue is obviously improved, sleep is safe, complexion is ruddy and no repetition occurs.
Case three: some women with deficiency of both qi and yin have obvious fatigue and weakness, and after 2 months, the women have no relief, and the women have dyspnea due to movement, chest distress, reduced interest, difficulty in falling asleep, anorexia and weight loss of 4 jin. After the granule prescription for defending spirit and relieving fatigue is taken for 2 weeks, the fatigue is obviously improved, the sleep is fast, chest distress and sweating are avoided, the consciousness is full, and the fatigue is not repeated.
Case four: zhenga certain, 26 years old men, 2 years fatigued and debilitated with 1 year waist soreness. Fatigue, weakness, shortness of breath, palpitation, subjective feeling of blockage in the throat, soreness of waist and weakness of legs occur in 2 years, and the treatment effect is not obvious in 2 years after traditional Chinese and western medicine. After the granule prescription for defending spirit and relieving fatigue is taken for 4 weeks, the fatigue is obviously improved, waist soreness and lumbago are avoided, conscious legs are powerful, throat blockage is basically eliminated, chest distress and sweating are avoided, vigor is high, weight is increased, and fatigue is not repeated.
In conclusion, the traditional Chinese medicine composition provided by the invention can relieve symptoms of fatigue, somnolence, dizziness and the like of patients with chronic fatigue syndrome, and has the effects of tonifying qi, raising yang, tonifying qi and strengthening exterior; clinical experiments prove that the medicine has definite curative effect on treating the fatigue syndrome, has obvious long-term effect after being subjected to tracking investigation for 3 months, and is worthy of clinical popularization and application.
The above embodiments are only illustrative of the preferred embodiments of the present invention and are not intended to limit the scope of the present invention, and various modifications and improvements made by those skilled in the art to the technical solutions of the present invention should fall within the protection scope defined by the claims of the present invention without departing from the design spirit of the present invention.
Claims (7)
1. A traditional Chinese medicine composition for treating qi-yin deficiency type chronic fatigue syndrome is characterized by comprising the following raw materials: 5-10g of ginseng, 5-15g of raw astragalus, 3-6g of cinnamon, 5-10g of angelica, 5-10g of white paeony root, 5-15g of kudzuvine root, 5-10g of wine sealwort, 5-12g of hairyvein agrimony, 5-10g of dwarf lilyturf tuber, 9-15g of raw dragon bone, 9-15g of raw oyster, 5-10g of silktree albizia flower, 10-20g of fried spina date seed, 5-10g of poria with hostwood, 5-10g of poria cocos, 5-10g of achyranthes root and 3-6g of honey-fried licorice root.
2. The traditional Chinese medicine composition according to claim 1, comprising the following raw materials: 6g of ginseng, 15g of raw astragalus, 3g of cinnamon, 10g of angelica, 10g of white peony root, 12g of kudzuvine root, 10g of rhizoma polygonati preparata, 12g of hairyvein agrimony, 10g of dwarf lilyturf tuber, 15g of raw dragon bone, 15g of raw oyster, 10g of albizia flower, 20g of fried spina date seed, 10g of poria with hostwood, 10g of poria cocos, 10g of achyranthes root and 6g of honey-fried licorice root.
3. A traditional Chinese medicine preparation for treating qi-yin deficiency type chronic fatigue syndrome, which is characterized in that the effective component of the traditional Chinese medicine preparation is the traditional Chinese medicine composition as claimed in claim 1 or 2.
4. The traditional Chinese medicine preparation for treating qi-yin deficiency type chronic fatigue syndrome according to claim 3, which is characterized by further comprising a pharmaceutically acceptable carrier and auxiliary materials.
5. Use of a traditional Chinese medicine composition according to any one of claims 1-2 or a traditional Chinese medicine preparation according to any one of claims 3-4 for preparing a medicament for treating qi-yin deficiency type chronic fatigue syndrome.
6. The use according to claim 5, wherein the dosage form of the medicament comprises granules.
7. The use according to claim 5, wherein the method of administration of the medicament comprises oral and parenteral administration.
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