CN115103858A - 一种抗体药物偶联物的制备方法 - Google Patents
一种抗体药物偶联物的制备方法 Download PDFInfo
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- CN115103858A CN115103858A CN202180014771.4A CN202180014771A CN115103858A CN 115103858 A CN115103858 A CN 115103858A CN 202180014771 A CN202180014771 A CN 202180014771A CN 115103858 A CN115103858 A CN 115103858A
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- drug conjugate
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Abstract
Description
Claims (15)
- PCT国内申请,权利要求书已公开。
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MX2022011770A (es) * | 2020-03-25 | 2022-10-18 | Jiangsu Hengrui Pharmaceuticals Co Ltd | Composicion farmaceutica que contiene un conjugado de anticuerpo-farmaco y uso de la misma. |
US11814394B2 (en) | 2021-11-16 | 2023-11-14 | Genequantum Healthcare (Suzhou) Co., Ltd. | Exatecan derivatives, linker-payloads, and conjugates and thereof |
WO2023232145A1 (zh) * | 2022-06-02 | 2023-12-07 | 华东师范大学 | 一种高喜树碱类小分子及其应用 |
WO2023237050A1 (en) * | 2022-06-09 | 2023-12-14 | Beigene, Ltd. | Antibody drug conjugates |
WO2024109840A1 (zh) * | 2022-11-22 | 2024-05-30 | 康诺亚生物医药科技(成都)有限公司 | 稠环类化合物及其偶联物和用途 |
WO2024153229A1 (zh) * | 2023-01-19 | 2024-07-25 | 江苏恒瑞医药股份有限公司 | 抗her2抗体药物偶联物治疗乳腺癌 |
WO2024208314A1 (zh) * | 2023-04-07 | 2024-10-10 | 长春金赛药业有限责任公司 | 喜树碱衍生物、药物组合物及其制备方法和应用 |
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US4970198A (en) | 1985-10-17 | 1990-11-13 | American Cyanamid Company | Antitumor antibiotics (LL-E33288 complex) |
US5079233A (en) | 1987-01-30 | 1992-01-07 | American Cyanamid Company | N-acyl derivatives of the LL-E33288 antitumor antibiotics, composition and methods for using the same |
US5606040A (en) | 1987-10-30 | 1997-02-25 | American Cyanamid Company | Antitumor and antibacterial substituted disulfide derivatives prepared from compounds possessing a methyl-trithio group |
US5530101A (en) | 1988-12-28 | 1996-06-25 | Protein Design Labs, Inc. | Humanized immunoglobulins |
US5208020A (en) | 1989-10-25 | 1993-05-04 | Immunogen Inc. | Cytotoxic agents comprising maytansinoids and their therapeutic use |
US5773001A (en) | 1994-06-03 | 1998-06-30 | American Cyanamid Company | Conjugates of methyltrithio antitumor agents and intermediates for their synthesis |
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2021
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- 2021-03-25 CA CA3175048A patent/CA3175048A1/en active Pending
- 2021-03-25 EP EP21774485.3A patent/EP4130045A4/en active Pending
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- 2021-03-25 WO PCT/CN2021/083014 patent/WO2021190602A1/zh unknown
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Publication number | Priority date | Publication date | Assignee | Title |
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CN118290514A (zh) * | 2024-06-05 | 2024-07-05 | 东曜药业有限公司 | 基于阴离子膜的抗体偶联药物的纯化方法及抗体偶联药物 |
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WO2021190602A1 (zh) | 2021-09-30 |
TW202144014A (zh) | 2021-12-01 |
US20230241242A1 (en) | 2023-08-03 |
AU2021243080A1 (en) | 2022-09-22 |
CA3175048A1 (en) | 2021-09-30 |
EP4130045A1 (en) | 2023-02-08 |
EP4130045A4 (en) | 2023-12-27 |
JP2023521956A (ja) | 2023-05-26 |
BR112022019042A2 (pt) | 2022-11-01 |
KR20220157425A (ko) | 2022-11-29 |
MX2022011769A (es) | 2022-10-18 |
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