CN114137196A - Reagent card for blood detection - Google Patents
Reagent card for blood detection Download PDFInfo
- Publication number
- CN114137196A CN114137196A CN202111484850.XA CN202111484850A CN114137196A CN 114137196 A CN114137196 A CN 114137196A CN 202111484850 A CN202111484850 A CN 202111484850A CN 114137196 A CN114137196 A CN 114137196A
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- Prior art keywords
- blood
- reagent card
- gas injection
- blood sampling
- waste liquid
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- 210000004369 blood Anatomy 0.000 title claims abstract description 86
- 239000008280 blood Substances 0.000 title claims abstract description 86
- 239000003153 chemical reaction reagent Substances 0.000 title claims abstract description 56
- 238000001514 detection method Methods 0.000 title claims abstract description 41
- 238000010241 blood sampling Methods 0.000 claims abstract description 57
- 238000012360 testing method Methods 0.000 claims abstract description 48
- 239000007788 liquid Substances 0.000 claims abstract description 46
- 239000000523 sample Substances 0.000 claims abstract description 41
- 239000002699 waste material Substances 0.000 claims abstract description 33
- HTTJABKRGRZYRN-UHFFFAOYSA-N Heparin Chemical compound OC1C(NC(=O)C)C(O)OC(COS(O)(=O)=O)C1OC1C(OS(O)(=O)=O)C(O)C(OC2C(C(OS(O)(=O)=O)C(OC3C(C(O)C(O)C(O3)C(O)=O)OS(O)(=O)=O)C(CO)O2)NS(O)(=O)=O)C(C(O)=O)O1 HTTJABKRGRZYRN-UHFFFAOYSA-N 0.000 claims abstract description 9
- 229960002897 heparin Drugs 0.000 claims abstract description 9
- 229920000669 heparin Polymers 0.000 claims abstract description 9
- 238000002347 injection Methods 0.000 claims description 46
- 239000007924 injection Substances 0.000 claims description 46
- 238000009534 blood test Methods 0.000 claims description 10
- 238000003756 stirring Methods 0.000 claims description 6
- 238000003780 insertion Methods 0.000 claims description 2
- 230000037431 insertion Effects 0.000 claims description 2
- 238000005259 measurement Methods 0.000 abstract description 5
- 230000035931 haemagglutination Effects 0.000 abstract description 2
- 238000005406 washing Methods 0.000 abstract description 2
- 210000001772 blood platelet Anatomy 0.000 description 8
- 230000023555 blood coagulation Effects 0.000 description 6
- 230000006870 function Effects 0.000 description 5
- 238000000034 method Methods 0.000 description 5
- 238000005070 sampling Methods 0.000 description 4
- 239000000243 solution Substances 0.000 description 3
- 230000008859 change Effects 0.000 description 2
- 238000005034 decoration Methods 0.000 description 2
- 229950003499 fibrin Drugs 0.000 description 2
- 238000012986 modification Methods 0.000 description 2
- 230000004048 modification Effects 0.000 description 2
- 230000008569 process Effects 0.000 description 2
- 102000015081 Blood Coagulation Factors Human genes 0.000 description 1
- 108010039209 Blood Coagulation Factors Proteins 0.000 description 1
- 206010053567 Coagulopathies Diseases 0.000 description 1
- 102000009123 Fibrin Human genes 0.000 description 1
- 108010073385 Fibrin Proteins 0.000 description 1
- BWGVNKXGVNDBDI-UHFFFAOYSA-N Fibrin monomer Chemical compound CNC(=O)CNC(=O)CN BWGVNKXGVNDBDI-UHFFFAOYSA-N 0.000 description 1
- 230000004913 activation Effects 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 239000003114 blood coagulation factor Substances 0.000 description 1
- 229940019700 blood coagulation factors Drugs 0.000 description 1
- 150000001720 carbohydrates Chemical class 0.000 description 1
- 230000035602 clotting Effects 0.000 description 1
- 239000011248 coating agent Substances 0.000 description 1
- 238000000576 coating method Methods 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 239000003792 electrolyte Substances 0.000 description 1
- 239000003822 epoxy resin Substances 0.000 description 1
- 239000000835 fiber Substances 0.000 description 1
- 230000005484 gravity Effects 0.000 description 1
- 230000006872 improvement Effects 0.000 description 1
- 230000003907 kidney function Effects 0.000 description 1
- 230000003908 liver function Effects 0.000 description 1
- 230000002107 myocardial effect Effects 0.000 description 1
- 229920000647 polyepoxide Polymers 0.000 description 1
- 229920000728 polyester Polymers 0.000 description 1
Images
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Hematology (AREA)
- Immunology (AREA)
- Urology & Nephrology (AREA)
- Cell Biology (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Abstract
The invention relates to a reagent card for blood detection, which comprises a reagent card body, a blood sampling tube slot, a detection port, a probe cavity, a test cup, a blood sampling pipeline and a liquid level detection assembly, wherein a blood sampling needle is arranged in the blood sampling tube slot and is communicated with the blood sampling pipeline, the blood sampling pipeline is communicated with a waste liquid chamber, and the waste liquid chamber is arranged in the reagent card body and close to the test cup. And then improved the detection efficiency of integrated device, meanwhile, the waste liquid chamber can get rid of the front end blood that has washed the blood sampling pipeline, avoids washing the contaminated blood sample entering test cup of blood sampling pipeline and influence the measurement accuracy, effectively improves the reliability that the device detected, makes that the staff is better carry out detection work to hemagglutination and platelet in the heparin tube.
Description
Technical Field
The invention relates to the technical field of blood detection, in particular to a reagent card for blood detection.
Background
The blood coagulation and Platelet Function analyzer can provide information such as blood coagulation factor activation, fibrin formation, Platelet Function and hyperfibrinolysis in sequence, monitors the whole blood coagulation process, provides index parameters such as ACT (Activated Clotting Time), CR (Clot Rate-fibrin generation Rate), PF (Platelet Function) and the like, and is widely applied to tests of liver Function, kidney Function, myocardial zymogram, saccharides, blood fat, electrolytes and the like due to the advantages of high measurement speed, high accuracy, small reagent consumption and the like. When testing and sampling, a blood sample needs to be manually sucked into a test cup, tools such as a needle head, a blood collection tube or an injector need to be adopted for transferring between adjacent processes, and the amount of reagents consumed by a blood coagulation and platelet function analyzer is small, so that the operation of workers is complicated, the detection speed is low, in addition, the blood collection tube has the risk of polluting the blood sample when in use, the final detection result is interfered, the detection accuracy is influenced, and the detection result is unreliable, so that the further improvement is needed.
Disclosure of Invention
The invention aims to overcome the defects in the prior art and provide a reagent card for blood detection, which effectively improves the blood sampling efficiency and reliability.
The invention is realized by the following technical scheme:
the utility model provides a reagent card for blood test, its characterized in that, including the reagent card body, locate the heparin tube slot on the reagent card body, set up in the detection mouth of reagent card body upper surface, locate probe cavity, the relative detection mouth of reagent card body one side and locate reagent card this internal test cup, communicate in the blood sampling pipeline between heparin tube slot and test cup and the liquid level detection subassembly that links to each other with the test cup upper end, be equipped with the blood taking needle in the heparin tube slot, the blood taking needle is linked together with the blood sampling pipeline, blood sampling pipeline intercommunication has the waste liquid room, the waste liquid room is located this internal and be close to the test cup setting of reagent card.
According to the above technical scheme, preferably, the blood collection tube slot is communicated with a gas injection assembly outside the reagent card body.
According to the above technical scheme, preferably, the gas injection subassembly is including locating the gas injection needle in the heparin tube slot, the gas injection pipeline that links to each other with the gas injection needle and locate the gas injection hole on the reagent card body lateral wall, the gas injection needle links to each other with the gas injection pipeline, the gas injection pipeline links to each other with the gas injection hole.
According to the technical scheme, preferably, the gas injection hole is a one-way duckbill valve gas injection hole.
According to the above technical scheme, preferably, the blood sampling pipeline is arranged at the upper part of the waste liquid chamber, the blood sampling pipeline is arranged above the waste liquid chamber and is provided with the liquid discharge hole, and the blood sampling pipeline is communicated with the waste liquid chamber through the liquid discharge hole.
According to the above technical solution, preferably, the liquid level detection assembly includes a blood sample collection filter communicated with the upper portion of the test cup.
According to the technical scheme, preferably, a blood detection window is arranged on the side wall of the reagent card body at a position corresponding to the blood sample collection filter.
According to the technical scheme, preferably, a stirring assembly is arranged in the test cup.
According to the above technical solution, preferably, the stirring component is a magnetic stirrer.
The invention has the beneficial effects that:
according to the invention, a trace amount of blood sample can be transferred into the test cup through the reagent card, so that manual operation is replaced, the operation procedure is simplified, the sampling time is shortened, and the detection efficiency of the whole device is further improved; meanwhile, the waste liquid chamber can be eliminated the front end blood that has washed the blood sampling pipeline, avoids washing the contaminated blood sample entering test cup of blood sampling pipeline and influence the measurement accuracy, effectively improves the reliability that the device detected, makes better the hemagglutination and the platelet to in the heparin tube of staff detect work.
Drawings
Fig. 1 is a schematic front view of the present invention.
Fig. 2 is a side view of the present invention.
Fig. 3 is a schematic perspective view of the present invention.
Fig. 4 is a front view schematically showing the structure of the waste liquid chamber part of the present invention.
Fig. 5 is a schematic top view of the present invention.
In the figure: 1. a blood collection tube slot; 2. a blood collection tube; 3. a one-way duckbill valve gas injection hole; 4. a waste chamber; 5. a blood detection window; 6. a probe chamber; 7. a blood sample collection filter; 8. a magnetic stirrer; 9. a test cup; 10. a blood collection pipeline; 11. an air injection pipeline; 12. a blood collection needle; 13. an air injection needle; 14. a drain hole; 15. and (6) a detection port.
Detailed Description
In order to make the technical solutions of the present invention better understood by those skilled in the art, the present invention will be further described in detail with reference to the accompanying drawings and preferred embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
In the description of the present invention, it should be noted that the terms "center", "upper", "lower", "left", "right", "vertical", "horizontal", "inner", "outer", and the like indicate orientations or positional relationships based on the orientations or positional relationships shown in the drawings, and are only for convenience of describing the invention and simplifying the description, but do not indicate or imply that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation, and thus, should not be construed as limiting the invention.
As shown in the figure, the blood sampling device comprises a reagent card body, a blood sampling tube slot 1 arranged on the reagent card body, a detection port 15 arranged on the upper surface of the reagent card body, a probe cavity 6 arranged on one side of the reagent card body, a test cup 9 arranged in the reagent card body opposite to the detection port 15, a blood sampling pipeline 10 communicated between the blood sampling tube slot 1 and the test cup 9, and a liquid level detection assembly connected with the upper end of the test cup 9, wherein a blood sampling needle 12 is arranged in the blood sampling tube slot 1, the blood sampling needle 12 is communicated with the blood sampling pipeline 10, the blood sampling pipeline 10 is communicated with a waste liquid chamber 4, and the waste liquid chamber 4 is arranged in the reagent card body and is close to the test cup 9. The probe has been pegged graft in the probe cavity 6, and probe and reagent card are disposable product, and the reagent card is before the use, and the open position of detection mouth 15 has the film to paste on the surface of reagent card for ensure reagent card interior cleanness, it is during the use to tear this layer of film and ensure that the probe gets into test cup 9 from the detection mouth, all contains a probe in every reagent card, detects the head before detecting at every turn and snatchs the probe, is used for detecting the blood sample in the test cup 9. According to the invention, a trace amount of blood sample can be transferred into the test cup 9 through the reagent card, manual operation is replaced, the operation procedure is simplified, the sampling time is shortened, and further the detection efficiency of the whole device is improved, meanwhile, the waste liquid chamber 4 can discharge the blood at the front end of the blood sampling pipeline 10 which is washed, the influence on the measurement accuracy caused by the fact that the blood sample polluted by the blood sampling pipeline 10 enters the test cup 9 is avoided, the detection reliability of the device is effectively improved, and workers can better detect the blood coagulation and the blood platelets in the blood sampling pipe.
According to the above embodiment, preferably, the blood sampling tube slot 1 is communicated with an air injection assembly outside the reagent card body, and the air injection assembly is used for transferring the blood sample in the blood sampling tube into the test cup 9 through the blood sampling pipeline 10.
According to the above embodiment, preferably, the gas injection assembly includes a gas injection needle 13 disposed in the blood collection tube insertion slot 1, a gas injection pipeline 11 connected to the gas injection needle 13, and a gas injection hole disposed on the sidewall of the reagent card body, the gas injection needle 13 is connected to the gas injection pipeline 11, the gas injection pipeline 11 is connected to a gas injection hole, which is a one-way duckbill valve gas injection hole 3 in this embodiment. The blood sampling tube that will gather blood inserts in blood sampling tube slot 1, and blood taking needle 12 and gas injection needle 13 insert simultaneously to the blood sampling intraductal this moment, to injecting into the air in one-way duckbill valve gas injection hole 3, the air flows into the blood sampling tube through gas injection pipeline 11, and atmospheric pressure makes the intraductal blood of blood sampling flow in to blood sampling pipeline 10 from blood taking needle 12, makes blood can smoothly flow into in the test cup 9.
Wherein, the effect of waste liquid room 4 lies in getting rid of the front end blood that washes blood sampling pipeline 10, and the blood of blood sampling pipeline 10 front end is at first through flowing back hole 14 entering waste liquid room 4 in, and the blood that flows into waste liquid room 4 can sink in the bottom because of self viscosity and gravity, and after waste liquid room 4 was filled, subsequent blood can directly get into test cup 9 through blood sampling pipeline 10, and the connected mode of waste liquid room 4 and blood sampling pipeline 10 can be realized through following means in this example: the blood sampling pipeline 10 is arranged on the upper portion of the waste liquid chamber 4 and penetrates through the upper portion of the waste liquid chamber 4, in the embodiment, the connecting position of the waste liquid chamber 4 and the blood sampling pipeline 10 is sealed by coating epoxy resin, the blood sampling pipeline 10 is positioned above the waste liquid chamber 4 and is provided with a liquid discharge hole 14, the blood sampling pipeline 10 is communicated with the waste liquid chamber 4 through the liquid discharge hole 14, the width size of the waste liquid chamber 4 in the embodiment is preferably 8mm, and the aperture of the liquid discharge hole 14 is 1.5-2.5 mm.
According to the above embodiment, preferably, the liquid level detection assembly comprises a blood sample collection filter 7 communicated with the upper part of the test cup 9, and the side wall of the reagent card body is provided with a blood detection window 5 at a position opposite to the blood sample collection filter 7. After the blood enters the test cup 9 for a certain amount, the excess part is sucked out by the blood sample collecting filter 7, so that the quantitative determination of the blood in the test cup 9 is ensured, in the embodiment, the blood sample collecting filter 7 consists of polyester fibers, the blood sample collecting filter 7 is white, turns red after blood suction, then the color change of the blood sample collecting filter 7 is detected by a color code sensor in an analyzer, whether the test cup 9 is filled with the blood is judged, when the test cup 9 is filled with the blood, the gas injection is stopped, and the blood stops being injected into the test cup 9.
According to the above embodiment, preferably, a stirring assembly is arranged in the test cup 9, and in this example, the stirring assembly is a magnetic stirrer 8, so that the blood sample in the test cup 9 can be effectively prevented from being layered.
The preferred mode of use of the invention is as follows:
a. inserting the reagent card body into a blood coagulation and platelet function analyzer, starting a detection head to grab a probe when a probe cavity 6 provided with the probe moves to the position below the detection head of the analyzer, continuously inserting the reagent card body inwards, and further moving a detection port 15 to the position below the detection head provided with the probe;
b. inserting a blood collection tube 2 which collects blood into a blood collection tube slot 1, injecting air into a one-way duckbill valve air injection hole 3, allowing the air to flow into the blood collection tube through an air injection pipeline 11, and allowing the blood in the blood collection tube 2 to flow into a blood collection pipeline 10 from a blood collection needle 12 under atmospheric pressure;
c. the blood in the blood sampling pipeline 10 firstly enters the waste liquid chamber 4, the blood flushed at the front end of the blood sampling pipeline 10 is discharged, and after the waste liquid chamber 4 is filled, the blood enters the test cup 9;
d. after the blood enters the test cup 9 for a certain amount, the excessive part is sucked out by the blood sample collecting filter 7, so that the quantitative determination of the blood in the test cup 9 is ensured;
e. the blood sample collection filter 7 is white and turns red after blood suction, then the color change of the blood sample collection filter 7 is detected through a color mark sensor in the analyzer, whether the test cup 9 is filled with blood or not is judged, and when the test cup 9 is filled with blood, gas injection is stopped, and the blood stops being injected into the test cup 9.
According to the invention, a trace amount of blood sample can be transferred into the test cup 9 through the reagent card, so that manual operation is replaced, the operation procedure is simplified, the sampling time is shortened, and the detection efficiency of the whole device is further improved; meanwhile, the waste liquid chamber 4 can remove the blood at the front end which is washed through the blood sampling pipeline 10, so that the polluted blood sample which is washed through the blood sampling pipeline 10 is prevented from entering the test cup 9 to influence the measurement accuracy, the detection reliability of the device is effectively improved, and the blood coagulation and the blood platelet in the blood sampling tube can be better detected by workers.
The foregoing is only a preferred embodiment of the present invention, and it should be noted that, for those skilled in the art, various modifications and decorations can be made without departing from the principle of the present invention, and these modifications and decorations should also be regarded as the protection scope of the present invention.
Claims (9)
1. The utility model provides a reagent card for blood test, its characterized in that, including the reagent card body, locate the heparin tube slot on the reagent card body, set up in the detection mouth of reagent card body upper surface, locate probe cavity, the relative detection mouth of reagent card body one side and locate reagent card this internal test cup, communicate in the blood sampling pipeline between heparin tube slot and test cup and the liquid level detection subassembly that links to each other with the test cup upper end, be equipped with the blood taking needle in the heparin tube slot, the blood taking needle is linked together with the blood sampling pipeline, blood sampling pipeline intercommunication has the waste liquid room, the waste liquid room is located this internal and be close to the test cup setting of reagent card.
2. The reagent card for blood test according to claim 1, wherein an air injection member is communicated with the blood collection tube insertion slot to the outside of the reagent card body.
3. The reagent card of claim 2, wherein the gas injection assembly comprises a gas injection needle disposed in the slot of the blood collection tube, a gas injection pipeline connected to the gas injection needle, and a gas injection hole disposed on a sidewall of the reagent card body, the gas injection needle is connected to the gas injection pipeline, and the gas injection pipeline is connected to the gas injection hole.
4. The reagent card for blood test according to claim 3, wherein the gas injection hole is a one-way duckbill valve gas injection hole.
5. The reagent card for blood test according to any one of claims 1 to 4, wherein the blood sampling tube is provided at an upper portion of the waste liquid chamber, the blood sampling tube is provided above the waste liquid chamber with a liquid discharge hole, and the blood sampling tube is communicated with the waste liquid chamber through the liquid discharge hole.
6. The reagent card for blood test according to claim 1, wherein the liquid level detection unit comprises a blood sample collection filter communicating with an upper portion of the test cup.
7. The reagent card for blood test according to claim 6, wherein a blood test window is provided on a side wall of the reagent card body at a position corresponding to the blood sample collection filter.
8. The reagent card for blood test according to claim 1 or 7, wherein a stirring member is provided in the test cup.
9. The reagent card for blood test according to claim 8, wherein the stirring member is a magnetic stirrer.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202111484850.XA CN114137196B (en) | 2021-12-07 | 2021-12-07 | Reagent card for blood detection |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202111484850.XA CN114137196B (en) | 2021-12-07 | 2021-12-07 | Reagent card for blood detection |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN114137196A true CN114137196A (en) | 2022-03-04 |
| CN114137196B CN114137196B (en) | 2024-08-13 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202111484850.XA Active CN114137196B (en) | 2021-12-07 | 2021-12-07 | Reagent card for blood detection |
Country Status (1)
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| CN (1) | CN114137196B (en) |
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| Publication number | Publication date |
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| CN114137196B (en) | 2024-08-13 |
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