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CN102552492A - Traditional Chinese medicinal composition for treating herpes zoster and preparation method thereof - Google Patents

Traditional Chinese medicinal composition for treating herpes zoster and preparation method thereof Download PDF

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Publication number
CN102552492A
CN102552492A CN201210023151XA CN201210023151A CN102552492A CN 102552492 A CN102552492 A CN 102552492A CN 201210023151X A CN201210023151X A CN 201210023151XA CN 201210023151 A CN201210023151 A CN 201210023151A CN 102552492 A CN102552492 A CN 102552492A
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radix
parts
chinese medicine
medicine composition
herpes zoster
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CN102552492B (en
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李晓鲁
戴红艳
尤淑玲
尤家平
闫素华
陈玉国
薛梅
胡和生
程文娟
李涛
蔡卫东
刘静静
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Shandong Qianfoshan Hospital
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Shandong Qianfoshan Hospital
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Abstract

The invention discloses a traditional Chinese medicinal composition for treating herpes zoster. The traditional Chinese medicinal composition contains the following raw materials of: by weight, 10-30 parts of Scorzonera austriaca Wild, 5-15 parts of cirsium ovalifolium, 5-15 parts of baikal skullcap root, 5-15 parts of radix paeoniae rubrathe, 5-15 parts of licorice, 10-20 parts of akebia stem, 10-20 parts of Plantain seed, 10-20 parts of rheum officinale, 5-15 parts of rhizoma atractylodis, 5-15 parts of bitter orange, 5-15 parts of gentian, 10-20 parts of isatis root, 10-20 parts of gentrin knotweed and 5-15 parts of periostracum cicadae. The traditional Chinese medicinal composition is a proved prescription, has effects of purging liver-gallbladder fire, invigorating spleen, eliminating dampness, relieving the depressed liver, invigorating blood circulation and relieving pain, has a wide drug resource, has no toxic and side effect, can be used to effectively treat herpes zoster, and has a substantial curative effect as well as high success rate. The effective rate of the composition reaches 89.2%.

Description

A kind of Chinese medicine composition of treating herpes zoster and preparation method thereof
Technical field
The present invention relates to contain the medicinal preparation that derives from plant material, particularly a kind of Chinese medicine composition of treating herpes zoster and preparation method thereof.
Background technology
Herpes zoster is sent out in the adult well, sees season in spring and autumn more.Sickness rate is remarkable rising with the age increase.No matter rash is arranged or do not have the rash type, the difficult dormancy of pain is its main feature, and the skin of diseased region has scorching hot, sensation of pricking, and after a couple of days, eruption type patient sees intensive vesicle, surrounding skin is rubescent, diseased region as burn burn pain.General Symptomies such as the visible lymphadenectasis that the state of an illness is more serious, heating.The local bunch of bubble that catchments does to troop zonal distribution along a side peripheral nerve, with obvious neuralgia.The people is unique host of varicella zoster virus, and virus gets into blood through respiratory mucosa and forms infection, and in the body of can hiding for a long time.When body receives certain stimulation (like wound, fatigue, malignant tumor or weakness etc. after being ill) when causing Abwehrkraft des Koepers to descend; Latent virus is activated; Along descending this nerve of arrival of sensory nerve axon arrange the zone skin in duplicate the generation vesicle; Getting involved simultaneously, nerve is inflamed, necrosis, produces neuralgia.General Symptomies such as slightly weak, low grade fever, poor appetite can be arranged before the dermexanthesis, conscious burning sensation of illing skin or neuralgia, that touches has tangible hyperpathia, continue 1~3 day, but also absence of prodrome is a dermexanthesis.Predilection site is followed successively by intercostal nerves, cervical nerves, nervi trigeminus and waist sacral nerves domination zone.The flushing speckle appears in affected part Chang Shouxian, occurs the pimple of foxtail millet grain to Semen Glycines size very soon, and bunch shape distributes and do not merge, and that continues becomes vesicle rapidly, and tonic vesicle wall is shinny, and limpid vesicle fluid, periphery are around blush, and skin is normal between each bunch vesicle crowd.Skin lesion is banded along peripheral nerve to be arranged, and mostly occurs in a side of health, generally is no more than median line.Varicella zoster virus be varicella zoster virus (varicella-zoster virus, VZV), this virus primary infection chickenpox (child), recurrent infection herpes zoster (adult).Because virus has neurotropism; Can hide for a long time in the neuron of spinal nerves posterior root ganglion after the infection; When lower for the resistance or tired, infection, cat fever, anger is got angry etc., and virus can regrow breeding; And move to skin along nerve fiber, make the nerve and the skin of being invaded produce fierce inflammation.The characteristics that erythra generally has one-sided property and distributes by nerve segment are made up of the herpes of collection bunch property, and with pain; Age is bigger, and neuralgia is heavier.This sick modern medicine is called herpes zoster, the Fel Serpentis skin ulcer that is called among the people, and the skirt-roof dragon flies titles such as Serpentis.
Herpes zoster belongs to pathogenic cold-damp and is driven outer general in the performance of skin by kidney-Yang; Only neuralgia is arranged and do not have (promptly not the having the rash type) of herpes; Belong to that kidney-Yang is unable drives the performance to skin with cold-damp, erythema or blister occur, belong to kidney-Yang pathogenic cold-damp is driven in the performance of skin table.General patient has slight heating, symptom such as tired a couple of days before herpes takes place, performance that kidney-Yang starts that Here it is.Herpes zoster heat syndrome patient skin flushing, tonic vesicle wall, sharp ache, with bitter taste in the mouth and dry throat, irritated irritability, yellow urine, big dry stool, red tongue, yellow fur, stringy and rolling pulse.Control suitable purging liver and gallbladder excess-fire.Wet disease patient skin is light red, flaccid vesicle wall, and pain is lighter, poor appetite or abdominal distention, big loose stool, pale tongue, tongue is white thick or white greasy, deep-slow pulse.Control suitable spleen invigorating dehumidifying.Local pain more than person in back belongs to qi depression to blood stasis if herpes zoster disappears, and controls suitable depressed liver-energy dispersing and QI regulating, promoting blood circulation and stopping pain.External Chinese medicine can be selected for use clearing heat, releasing toxin, removing swelling or damp eliminating to receive dried liquid medicine according to the state of an illness and fry in shallow oil external application.No matter which kind of method, the treatment of herpes zoster should be grasped opportunity, and the early treatment effect is good more more.Frequent some middle-older patient, still gnawing pains take no rest after herpes zoster is cleared up and discharged fully, and local skin is excellent but dare not to be touched.The body constitution of its pain is get involved ganglionic inflammation even necrosis, and the degree weight of pain and time length and erythra not necessarily are consistent.Especially old people, the various functions of body are all going down with advancing age, and difficulty is repaired also by impaired nervous tissue, so be easy to take place post herpetic neuralgia.Particularly body constitution is relatively poor usually, or treats untimely person, the sustainable several months of this kind pain even more of a specified duration.
The common therapy Chang Buneng of herpes zoster is completely cured, though the herpes remission, but still gnawing pains take no rest.Chinese medicine is one of culture rarity of the Chinese nation, and it has significant curative effect for the treatment herpes zoster, and it is in the purging liver and gallbladder excess-fire, and spleen invigorating dehumidifies, depressed liver-energy dispersing and QI regulating, and promoting blood circulation and stopping pain aspect effect is remarkable, and the medicine source is many from plant extract, has no side effect.Chinese medicine has its unique advantage on the treatment herpes zoster.
Summary of the invention
Technical problem to be solved by this invention is; A kind of purging liver and gallbladder excess-fire is provided, spleen invigorating dehumidifying, depressed liver-energy dispersing and QI regulating; Promoting blood circulation and stopping pain aspect effect is remarkable; And the medicine source extensively, have no side effect, can effectively treat herpes zoster, a kind of Chinese medicine composition of treating herpes zoster of its obvious results and preparation method thereof.
For solving the problems of the technologies described above, the invention provides a kind of Chinese medicine composition of treating herpes zoster, wherein, each crude drug is following than configuration according to weight fraction: Radix Scorzonerae austriacae 10-30 part, Elephantopus scaber L. 5-15 part; Radix Scutellariae 5-15 part, Radix Paeoniae Rubra 5-15 part, Radix Glycyrrhizae 5-15 part, Caulis Akebiae 10-20 part; Semen Plantaginis 10-20 part, Radix Et Rhizoma Rhei 10-20 part, Rhizoma Atractylodis 5-15 part, Fructus Aurantii 5-15 part; Radix Gentianae 5-15 part, Radix Isatidis 10-20 part, Rhizoma Polygoni Cuspidati 10-20 part, Periostracum Cicadae 5-15 part.
Perhaps, each crude drug is following than configuration according to weight fraction: Radix Scorzonerae austriacae 20-30 part, Elephantopus scaber L. 10-15 part, Radix Scutellariae 10-15 part; Radix Paeoniae Rubra 10-15 part, Radix Glycyrrhizae 10-15 part, Caulis Akebiae 15-20 part, Semen Plantaginis 15-20 part; Radix Et Rhizoma Rhei 15-20 part, Rhizoma Atractylodis 10-15 part, Fructus Aurantii 10-15 part, Radix Gentianae 10-15 part; Radix Isatidis 15-20 part, Rhizoma Polygoni Cuspidati 15-20 part, Periostracum Cicadae 10-15 part.
Perhaps, each crude drug is following than configuration according to weight fraction: Radix Scorzonerae austriacae 10-20 part, Elephantopus scaber L. 5-10 part, Radix Scutellariae 5-10 part; Radix Paeoniae Rubra 5-10 part, Radix Glycyrrhizae 5-10 part, Caulis Akebiae 10-15 part, Semen Plantaginis 10-15 part; Radix Et Rhizoma Rhei 10-15 part, Rhizoma Atractylodis 5-10 part, Fructus Aurantii 5-10 part, Radix Gentianae 5-10 part; Radix Isatidis 10-15 part, Rhizoma Polygoni Cuspidati 10-15 part, Periostracum Cicadae 5-10 part.
Perhaps, each crude drug is following than configuration according to weight fraction: Radix Scorzonerae austriacae 15-25 part, Elephantopus scaber L. 8-12 part, Radix Scutellariae 8-12 part; Radix Paeoniae Rubra 8-12 part, Radix Glycyrrhizae 8-12 part, Caulis Akebiae 12-16 part, Semen Plantaginis 12-16 part; Radix Et Rhizoma Rhei 12-16 part, Rhizoma Atractylodis 8-12 part, Fructus Aurantii 8-12 part, Radix Gentianae 8-12 part; Radix Isatidis 12-16 part, Rhizoma Polygoni Cuspidati 12-16 part, Periostracum Cicadae 8-12 part.
Chinese medicine composition of the present invention when use is fried in shallow oil decoction and is taken, 1 dose of every day, clothes at twice, per 7 days is a course of treatment.
The dosage form of Chinese medicine composition of the present invention is: honey refining pill, hydration pill, capsule, oral liquid, tablet, drop pill or syrup.
Be better to realize the object of the invention, the present invention also provides a kind of method for preparing of treating the Chinese medicine composition of herpes zoster, and wherein, when the dosage form of Chinese medicine composition be that honey refines pill, its preparation method is:
Said each crude drug was soaked 30 minutes to 1 hour, and heated and boiled 30 minutes is filtered filtrate for later use; Filtering residue adds water, and heating was boiled 30 minutes for the second time, refiltered filtrate for later use; Filtering residue adds water again, and heated and boiled is 40 minutes for the third time, filters; Three filtratings are lumped together, and heating is concentrated into pasty state, puts into baking oven, is controlled at 80 ℃, dries postcooling, and mixing with Mel is twisted into slice, processes honey refining ball and wax seal packing.
When the dosage form of Chinese medicine composition is a capsule, its preparation method is:
Said crude drug is added the ethanol of 10 times of amounts of weight, heating and refluxing extraction 3 times, each 2 hours, 3 extracting solution are merged, decompression recycling ethanol, and to be concentrated into liquor strength be 0.5g crude drug/mL is behind the sucking filtration, when the relative density of filtrating is 20 ℃ 1.08; Said filtrate flow is the adsorption resin column of 10L through volume, uses the deionized water or the distilled water eluting of 10 times of resin column volumes afterwards, 95% ethanol elution of 5 times of resin column volumes of reuse; Collect ethanol elution; Remove alcohol solvent, obtain component medicated powder, incapsulate and be made as capsule.
When the dosage form of Chinese medicine composition is a tablet, its preparation method is:
Said each crude drug chopping is joined in the multi-function extractor, and the adding ratio of weight and number is that 3000 parts water logging was steeped 30~40 minutes, decocts after 1.5 hours, and decoction liquor is subsequent use for the first time in taking-up; Medicinal residues adding ratio of weight and number is after 3000 parts decocting boils 1 hour, to take out decoction liquor for the second time, aforementioned twice decoction liquor is merged filter; It is 1000 parts solution that filtrate decompression is concentrated into ratio of weight and number, staticly settles 24~36 hours, draws supernatant; Add starch after being heated to 40~50 ℃, heating is concentrated into pasty state, puts into baking oven; Be controlled at 80 ℃, oven dry postcooling, film-making, drying, molding, packing.
Chinese medicine composition of the present invention, eliminating pathogen in the liver gallbladder excess-fire, spleen invigorating dehumidifying, depressed liver-energy dispersing and QI regulating, promoting blood circulation and stopping pain, and the medicine source extensively, have no side effect, can effectively treat herpes zoster and pain symptom thereof, therapeutic effect is remarkable, success rate is high, effective percentage reaches 89.2%.
The specific embodiment
The invention discloses a kind of Chinese medicine composition of treating herpes zoster, wherein, each crude drug is following than configuration according to weight fraction: Radix Scorzonerae austriacae 10-30 part, Elephantopus scaber L. 5-15 part; Radix Scutellariae 5-15 part, Radix Paeoniae Rubra 5-15 part, Radix Glycyrrhizae 5-15 part, Caulis Akebiae 10-20 part; Semen Plantaginis 10-20 part, Radix Et Rhizoma Rhei 10-20 part, Rhizoma Atractylodis 5-15 part, Fructus Aurantii 5-15 part; Radix Gentianae 5-15 part, Radix Isatidis 10-20 part, Rhizoma Polygoni Cuspidati 10-20 part, Periostracum Cicadae 5-15 part.
Perhaps, each crude drug is following than configuration according to weight fraction: Radix Scorzonerae austriacae 20-30 part, Elephantopus scaber L. 10-15 part, Radix Scutellariae 10-15 part; Radix Paeoniae Rubra 10-15 part, Radix Glycyrrhizae 10-15 part, Caulis Akebiae 15-20 part, Semen Plantaginis 15-20 part; Radix Et Rhizoma Rhei 15-20 part, Rhizoma Atractylodis 10-15 part, Fructus Aurantii 10-15 part, Radix Gentianae 10-15 part; Radix Isatidis 15-20 part, Rhizoma Polygoni Cuspidati 15-20 part, Periostracum Cicadae 10-15 part.
Perhaps, each crude drug is following than configuration according to weight fraction: Radix Scorzonerae austriacae 10-20 part, Elephantopus scaber L. 5-10 part, Radix Scutellariae 5-10 part; Radix Paeoniae Rubra 5-10 part, Radix Glycyrrhizae 5-10 part, Caulis Akebiae 10-15 part, Semen Plantaginis 10-15 part; Radix Et Rhizoma Rhei 10-15 part, Rhizoma Atractylodis 5-10 part, Fructus Aurantii 5-10 part, Radix Gentianae 5-10 part; Radix Isatidis 10-15 part, Rhizoma Polygoni Cuspidati 10-15 part, Periostracum Cicadae 5-10 part.
Perhaps, each crude drug is following than configuration according to weight fraction: Radix Scorzonerae austriacae 15-25 part, Elephantopus scaber L. 8-12 part, Radix Scutellariae 8-12 part; Radix Paeoniae Rubra 8-12 part, Radix Glycyrrhizae 8-12 part, Caulis Akebiae 12-16 part, Semen Plantaginis 12-16 part; Radix Et Rhizoma Rhei 12-16 part, Rhizoma Atractylodis 8-12 part, Fructus Aurantii 8-12 part, Radix Gentianae 8-12 part; Radix Isatidis 12-16 part, Rhizoma Polygoni Cuspidati 12-16 part, Periostracum Cicadae 8-12 part.
When Chinese medicine composition of the present invention is fried in shallow oil decoction in use and is taken, 1 dose of every day, clothes at twice, per 7 days is a course of treatment.
The dosage form of Chinese medicine composition of the present invention is: honey refining pill, hydration pill, capsule, oral liquid, tablet, drop pill or syrup.
Each composition among the present invention:
Radix Scorzonerae austriacae, hardship, cold.Be used for heat-clearing and toxic substances removing, promoting blood circulation and detumescence.Furuncle is controlled in external, carbuncle, venom, mosquito bite, mastitis etc.Subduing swelling and detoxicating.Main infirmities and diseases; The furuncle carbuncle." Jiangsu medical material will ": subduing swelling and detoxicating.Control infirmities and diseases, the furuncle carbuncle." Ningxia Chinese herbal medicine handbook: little hardship, cold.
Elephantopus scaber L., performance: cold in nature, bitter in the mouth is hot; Heat-clearing and toxic substances removing, removing heat from blood detumescence, cough-relieving diuresis.Be used for heat-clearing and toxic substances removing, inducing diuresis to remove edema.Be used for flu, acute tonsillitis, pharyngolaryngitis, eye conjunctivitis, epidemic encephalitis type B, pertussis, acute icterohepatitis, cirrhotic ascites, acute and chronic nephritis, furuncle and phyma, eczema.
Radix Scutellariae can be controlled the pestilence heating, cough due to lung-heat, jaundice due to damp-heat, and diseases such as dysentery, frequent fetal movement, and effects such as antibiotic, analgesic, blood pressure lowering, the clear pestilence of pathogenic fire purging are arranged.
Radix Paeoniae Rubra, hardship is slightly cold.Return Liver Channel.Clearing away heat and cooling blood, eliminating stasis to stop pain.Be used for maculae caused by violent heat pathogen, hematemesis and epistaxis, conjunctival congestion and swelling pain, hypochondriac pain due to stagnation of liverQI, amenorrhea dysmenorrhea, lump in the abdomen stomachache, injury from falling down, carbuncle skin infection." herbal classic ": " bitter in the mouth, flat." " WU Pu Bencao ": " paulownia monarch: sweet, nontoxic.Fork primary: become.Li Shi: Slight Cold.Thunder God: acid." " not Lu ": " and acid, flat being slightly cold, slightly poisonous." amplification on Canon of Materia Medica: " puckery is bitter." go into liver, spleen channel.
Radix Glycyrrhizae, property is flat, and sweet in the mouth is returned 12 warps.Detoxifcation arranged, eliminate the phlegm, pain relieving, spasmolytic be so that pharmacological action such as anticancer.On the traditional Chinese medical science, be in harmonious proportion hundred medicines. invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain, coordinating the actions of various ingredients in a prescription.Be used for weakness of the spleen and stomach, fatigue and weakness, shortness of breath and palpitation, cough with copious phlegm, gastral cavity abdomen, the anxious pain of extremity contraction, carbuncle sore tumefacting virus, cushion toxicity, strong." book on Chinese herbal medicine converges and says ": Radix Glycyrrhizae and middle QI invigorating, the medicine of tonify deficiency detoxifcation also.Strengthening the spleen and stomach, Gu the weakness with emaciation of middle gas, association's negative and positive and uncomfortable battalion defend.So control the strain internal injury, deficiency-weakness of spleen-QI, first YANG deficiency, the lung qi void that declines, its Gan Wenping mends, and effect and ginseng, stilbene are also also.Laryngopharynx swelling and pain and for example, assistant Fructus Aurantii Immaturus, Mus are sticking, can lung heat clearing open pharynx; Sputum cough, Fructus Perillae, two old altogether, can expectorant pleasant.. " book on Chinese herbal medicine is newly organized ": Radix Glycyrrhizae, sweet in the mouth, gas is flat, and is warm in nature, can rise and can fall, and positive middle-jiao yang, function of the spleen and stomach is also.Nontoxic.Go into the warp of lunar, few the moon, the moon of fainting.
Caulis Akebiae, nature and flavor: bitter, be slightly cold.Gui Jing: go into heart channel, small intestine meridian, urinary bladder channel.Function: clearing away heart-fire, diuresis, the stimulating milk secretion of stimulating the menstrual flow.Cure mainly: be used for irritable feverish sensation in the chest, sore throat pharyngalgia, dark coloured urine, five types of stranguria, edema, whole body spasm and pain."Do not record": spa spleen jaundice often want to sleep, upset hiccup, the sounds, cure deafness, loose knot Needless carbuncles Zhu, and gold sores, malignant sore, rats atrophy, Wei fold, Weng nasal polyps, abortion, go three worms.
Semen Plantaginis, sweet, cold." herbal classic ": main stranguria due to disorder of QI, pain relieving, dredging water passages urine is removed arthralgia chiefly caused by damp pathogen." Shandong Chinese medicine ": apply eczema, impetigo, children's's head sore." property of medicine is sunk ": can remove pathogenic wind toxic, the liver affected by pathogenic wind heat, malicious wind dotting punch order, swelling pain is hidden from view, and irritable feverish sensation of chest and heart is removed in the headache lacrimation.
Radix Et Rhizoma Rhei, nature and flavor: hardship, cold.Gui Jing: stomach warp; Large intestine channel; Liver Channel; Spleen channel.Effect: attack stagnant; Clearing away damp-heat; Pathogenic fire purging; Removing heat from blood; Blood stasis dispelling; Detoxifcation.Cure mainly: the excess-heat constipation; The accumulation of heat feeling of stuffiness in chest; Damp-heat dysentery; Jaundice; Gonorrhea; The edema abdominal distention; Dysuria; Conjunctival congestion; Laryngopharynx swelling and pain; Aphtha of the mouth and tongue; Gastropyretic vomiting; Spit blood; Spitting of blood; Epistaxis; Have blood in stool; Hematuria; Blood-retention; Amenorrhea; The stasis of blood stagnated and suffered from abdominal pain puerperal; Lump in the abdomen; Traumatic injury; Pyretic toxicity carbuncle and ulcer; Erysipelas; Scald.Purging heat and dredging bowels, removing pathogenic heat from blood and toxic substance from the body, eliminating blood stasis and inducing menstruation.Be used for the excess-heat constipation, stagnant stomachache, dysentery is not well, jaundice due to damp-heat, heat in blood is told nosebleed, conjunctival congestion, pharyngeal swelling, abdominalgia with intestinal abscess, carbuncle furuncle, blood stasis amenorrhea, traumatic injury, external treatment burn due to hot liquid or fire; Upper gastrointestinal hemorrhage.Radix et Rhizoma Rhei (stir-fried with wine) is apt to clear part of the body cavity above the diaphragm housing the heart and lungs noxious heat in the blood system.Be used for the conjunctival congestion pharyngeal swelling, gingivitis.Radix Et Rhizoma Rhei rushes down exerts oneself to delay eliminating fire and detoxication.Be used for pathogenic fire,toxin and furuncles.The hemostasis of charred Radix Et Rhizoma Rhei cooling blood and removing stasis.Be used for heat in blood stasis of blood bleeder is arranged.
Rhizoma Atractylodis, hot, bitter, temperature.Return spleen, stomach, Liver Channel.Drying damp and strengthening spleen, expelling wind and cold makes eye bright.Be used for distension and fullness in the abdomen, the edema of having loose bowels, the beriberi flaccidity is preesed, rheumatic arthralgia, anemofrigid cold, nyctalopia.
Fructus Aurantii, nature and flavor are bitter; Acid; Cold nature is returned through lung; Spleen; Liver; Stomach; The large intestine channel function cures mainly: the septum pectorale feeling of fullness; Distending pain over the hypochondrium; Accumulation of food in the stomach and intes tine due to indigestion; Distension and fullness in the abdomen; Heavy behind the dysentery; Proctoptosis; Uterine prolapse.Controlling rubella itches incessantly.
Radix Gentianae has the effect of heat clearing away, eliminating pathogen in the liver, arresting convulsion.The Compendium of Material Medica record: " nature and flavor are bitter, and are puckery, Great Cold, nontoxic.Cure mainly cold and heat between bone, frightened pathogenic factor gas, the exhausted wound that continues is decided the five internal organs, the parasite killing poison.". " Japan hanako materia medica ": control infantile convulsive seizure due to fright, infantile malnutrition mansion gas, the calentura delirium, the skin ulcer scabies makes eye bright, and ends tired.
Radix Isatidis has antibiosis and antiviral functions and Detoxication." book on Chinese herbal medicine is stated ": hardship, cold, nontoxic.Heat clearing away, detoxifcation, removing heat from blood, sore-throat relieving.Cure mainly: maculae caused by violent heat pathogen; The hyperpyrexia headache; Major part pestilence; Crimson tongue is purple dark, scarlet fever; Erysipelas; Mumps; Sore throat; Skin ulcer is swollen, carbuncle; Chickenpox; Measles; Hepatitis; Influenza, epidemic encephalitis, encephalitis b, pneumonia, coma is told nosebleed, pharyngeal swelling, acute catarrhal conjunctivitis, skin ulcer rash; Can prevent and treat epidemic encephalitis type B, acute, chronic hepatitis, mumps, osteomyelitis.
Rhizoma Polygoni Cuspidati, little hardship is slightly cold.Return liver, gallbladder, lung meridian.Function with cure mainly: heat-clearing and toxic substances removing, promoting the function of the gallbladder to alleviate jaundice, expelling wind and removing dampness, dissipating blood stasis analgesic therapy, relieving cough and resolving phlegm.Be used for arthralgia, jaundice due to damp-heat, amenorrhea , WEIJIA, cough with copious phlegm, burn due to hot liquid or fire, injury from falling down, carbuncle sore tumefacting virus.
Periostracum Cicadae: sweet, cold.Return lung, Liver Channel.Function: the wind heat extraction that looses, sore-throat relieving, rash, nebula removing, spasmolytic.Be used for anemopyretic cold, pharyngalgia, hoarseness, measles without adequate eruption, rubella pruritus, conjunctival congestion cataracta, convulsion with spasms, tetanus.
In the method for preparing:
The dosage form of Chinese medicine composition of the present invention is a honey refining pill, and its preparation method is:
Said each crude drug was soaked 30 minutes to 1 hour, and heated and boiled 30 minutes is filtered filtrate for later use; Filtering residue adds water, and heating was boiled 30 minutes for the second time, refiltered filtrate for later use; Filtering residue adds water again, and heated and boiled is 40 minutes for the third time, filters; Three filtratings are lumped together, and heating is concentrated into pasty state, puts into baking oven, is controlled at 80 ℃, dries postcooling, and mixing with Mel is twisted into slice, processes honey refining ball and wax seal packing.
The dosage form of Chinese medicine composition of the present invention is a capsule, and its preparation method is:
Said crude drug is added the ethanol of 10 times of amounts of weight, heating and refluxing extraction 3 times, each 2 hours, 3 extracting solution are merged, decompression recycling ethanol, and to be concentrated into liquor strength be 0.5g crude drug/mL is behind the sucking filtration, when the relative density of filtrating is 20 ℃ 1.08; Said filtrate flow is the adsorption resin column of 10L through volume, uses the deionized water or the distilled water eluting of 10 times of resin column volumes afterwards, 95% ethanol elution of 5 times of resin column volumes of reuse; Collect ethanol elution; Remove alcohol solvent, obtain component medicated powder, incapsulate and be made as capsule.
The dosage form of Chinese medicine composition of the present invention is a tablet, and its preparation method is:
Said each crude drug chopping is joined in the multi-function extractor, and the adding ratio of weight and number is that 3000 parts water logging was steeped 30~40 minutes, decocts after 1.5 hours, and decoction liquor is subsequent use for the first time in taking-up; Medicinal residues adding ratio of weight and number is after 3000 parts decocting boils 1 hour, to take out decoction liquor for the second time, aforementioned twice decoction liquor is merged filter; It is 1000 parts solution that filtrate decompression is concentrated into ratio of weight and number, staticly settles 24~36 hours, draws supernatant; Add starch after being heated to 40~50 ℃, heating is concentrated into pasty state, puts into baking oven; Be controlled at 80 ℃, oven dry postcooling, film-making, drying, molding, packing.
Specifically be exemplified below
Embodiment 1: Mr. Wang, man, 24 years old.Patient skin is light red gets blister, and the bubble wall is lax, and broken back erosion is oozed out, and pain is lighter, thirsty and desire drink not, and poor appetite or abdominal distention after meal, big loose stool, pale tongue is fat, the deep pulse moderate and slippery pulse.Be the herpes zoster patient after diagnosing, use prescription as follows: Radix Scorzonerae austriacae 30g, Elephantopus scaber L. 15g, Radix Scutellariae 15g, Radix Paeoniae Rubra 15g, Radix Glycyrrhizae 15g, Caulis Akebiae 20g, Semen Plantaginis 20g, Radix Et Rhizoma Rhei 20g, Rhizoma Atractylodis 15g, Fructus Aurantii 15g, Radix Gentianae 15g, Radix Isatidis 20g, Rhizoma Polygoni Cuspidati 20g, Periostracum Cicadae 15g.Fry in shallow oil decoction during use and take, obey at twice 1 dose of every day, per 7 days is a course of treatment.After taking 2 courses of treatment, symptom goes down, and continues to take 1 course of treatment, and herpes zoster disappears, and consolidates and fully recovers after curative effect continued to take 1 course of treatment, visits after half a year, not recurrence.
Embodiment 2: the Ms Zhang, and 39 years old, the patient skin flushing had blister, tonic vesicle wall, scorching hot twinge forms red foxtail millet, and bitter taste in the mouth and dry throat is thirsty, irritated irritability, oliguria with reddish urine, constipation with dry stool, red tongue, yellow and thin fur, deep pulse moderate and slippery pulse.Be the herpes zoster patient after diagnosing, use prescription as follows: Radix Scorzonerae austriacae 10g, Elephantopus scaber L. 5g, Radix Scutellariae 5g, Radix Paeoniae Rubra 5g, Radix Glycyrrhizae 5g, Caulis Akebiae 10g, Semen Plantaginis 10g, Radix Et Rhizoma Rhei 10g, Rhizoma Atractylodis 5g, Fructus Aurantii 5g, Radix Gentianae 5g, Radix Isatidis 10g, Rhizoma Polygoni Cuspidati 10g, Periostracum Cicadae 5g.Fry in shallow oil decoction during use and take, obey at twice 1 dose of every day, per 7 days is a course of treatment.After taking 3 courses of treatment, symptom goes down, and continues to take 1 course of treatment, and herpes zoster disappears, and consolidates and fully recovers after curative effect continued to take 1 course of treatment, visits after three months, not recurrence.
Embodiment 3: Mr. Li, and 53 years old, the patient skin flushing, tonic vesicle wall has blister, sharp ache, with bitter taste in the mouth and dry throat, irritated irritability, yellow urine, big dry stool, red tongue, yellow fur, stringy and rolling pulse.Be the herpes zoster patient after diagnosing, use prescription as follows: Radix Scorzonerae austriacae 15g, Elephantopus scaber L. 8g, Radix Scutellariae 8g, Radix Paeoniae Rubra 8g, Radix Glycyrrhizae 8g, Caulis Akebiae 12g, Semen Plantaginis 12g, Radix Et Rhizoma Rhei 12g, Rhizoma Atractylodis 8g, Fructus Aurantii 8g, Radix Gentianae 8g, Radix Isatidis 12g, Rhizoma Polygoni Cuspidati 12g, Periostracum Cicadae 8g.Fry in shallow oil decoction during use and take, obey at twice 1 dose of every day, per 7 days is a course of treatment.After taking 2 courses of treatment, symptom goes down, and continues to take 2 courses of treatment, and herpes zoster disappears, and consolidates and fully recovers after curative effect continued to take 1 course of treatment, visits after half a year, not recurrence.
Embodiment 4: Zhang auntie, 47 years old, skin was light red, and the bleb wall is not obvious, and pleurobranch wall local pain is heavier, poor appetite or abdominal distention; Big loose stool, pale tongue, tongue is thick in vain, is the herpes zoster patient after diagnosing, uses prescription as follows: Radix Scorzonerae austriacae 25g, Elephantopus scaber L. 12g; Radix Scutellariae 12g, Radix Paeoniae Rubra 12g, Radix Glycyrrhizae 12g, Caulis Akebiae 16g, Semen Plantaginis 16g, Radix Et Rhizoma Rhei 16g; Rhizoma Atractylodis 12g, Fructus Aurantii 12g, Radix Gentianae 12g, Radix Isatidis 16g, Rhizoma Polygoni Cuspidati 16g, Periostracum Cicadae 12g.Fry in shallow oil decoction during use and take, obey at twice 1 dose of every day, per 7 days is a course of treatment.After taking 2 courses of treatment, symptom goes down, and continues to take 1 course of treatment, and herpes zoster disappears, and consolidates and fully recovers after curative effect continued to take 1 course of treatment, visits after half a year, not recurrence.
Use the present invention prescription, the first half of the year in 2011 accepted for medical treatment in 120 examples, and effective percentage reaches 89.2%.The Chinese medicine composition that the present invention is clear, eliminating pathogen in the liver gallbladder excess-fire, spleen invigorating dehumidifying, depressed liver-energy dispersing and QI regulating, promoting blood circulation and stopping pain, and the medicine source extensively, have no side effect, can effectively treat herpes zoster, therapeutic effect is remarkable, success rate is high.

Claims (9)

1. a Chinese medicine composition of treating herpes zoster is characterized in that, each crude drug is following than configuration according to weight fraction: Radix Scorzonerae austriacae 10-30 part, Elephantopus scaber L. 5-15 part; Radix Scutellariae 5-15 part, Radix Paeoniae Rubra 5-15 part, Radix Glycyrrhizae 5-15 part, Caulis Akebiae 10-20 part; Semen Plantaginis 10-20 part, Radix Et Rhizoma Rhei 10-20 part, Rhizoma Atractylodis 5-15 part, Fructus Aurantii 5-15 part; Radix Gentianae 5-15 part, Radix Isatidis 10-20 part, Rhizoma Polygoni Cuspidati 10-20 part, Periostracum Cicadae 5-15 part.
2. according to the Chinese medicine composition of the said treatment herpes zoster of claim 1, it is characterized in that each crude drug is following than configuration according to weight fraction: Radix Scorzonerae austriacae 20-30 part, Elephantopus scaber L. 10-15 part; Radix Scutellariae 10-15 part, Radix Paeoniae Rubra 10-15 part, Radix Glycyrrhizae 10-15 part, Caulis Akebiae 15-20 part; Semen Plantaginis 15-20 part, Radix Et Rhizoma Rhei 15-20 part, Rhizoma Atractylodis 10-15 part, Fructus Aurantii 10-15 part; Radix Gentianae 10-15 part, Radix Isatidis 15-20 part, Rhizoma Polygoni Cuspidati 15-20 part, Periostracum Cicadae 10-15 part.
3. according to the Chinese medicine composition of the said treatment herpes zoster of claim 1, it is characterized in that each crude drug is following than configuration according to weight fraction: Radix Scorzonerae austriacae 10-20 part, Elephantopus scaber L. 5-10 part; Radix Scutellariae 5-10 part, Radix Paeoniae Rubra 5-10 part, Radix Glycyrrhizae 5-10 part, Caulis Akebiae 10-15 part; Semen Plantaginis 10-15 part, Radix Et Rhizoma Rhei 10-15 part, Rhizoma Atractylodis 5-10 part, Fructus Aurantii 5-10 part; Radix Gentianae 5-10 part, Radix Isatidis 10-15 part, Rhizoma Polygoni Cuspidati 10-15 part, Periostracum Cicadae 5-10 part.
4. according to the Chinese medicine composition of the said treatment herpes zoster of claim 1, it is characterized in that each crude drug is following than configuration according to weight fraction: Radix Scorzonerae austriacae 15-25 part, Elephantopus scaber L. 8-12 part; Radix Scutellariae 8-12 part, Radix Paeoniae Rubra 8-12 part, Radix Glycyrrhizae 8-12 part, Caulis Akebiae 12-16 part; Semen Plantaginis 12-16 part, Radix Et Rhizoma Rhei 12-16 part, Rhizoma Atractylodis 8-12 part, Fructus Aurantii 8-12 part; Radix Gentianae 8-12 part, Radix Isatidis 12-16 part, Rhizoma Polygoni Cuspidati 12-16 part, Periostracum Cicadae 8-12 part.
5. according to the Chinese medicine composition of each said treatment herpes zoster among the claim 1-4, it is characterized in that, when said Chinese medicine composition is fried in shallow oil decoction in use and is taken, 1 dose of every day, clothes at twice, per 7 days is a course of treatment.
6. according to the Chinese medicine composition of claim, it is characterized in that the dosage form of said Chinese medicine composition is: honey refining pill, hydration pill, capsule, oral liquid, tablet, drop pill or syrup according to each said treatment herpes zoster among the claim 1-4.
7. the Chinese medicine composition of each said treatment herpes zoster among the claim 1-3 is characterized in that, the dosage form of said Chinese medicine composition is a honey refining pill, and its preparation method is:
Said each crude drug was soaked 30 minutes to 1 hour, and heated and boiled 30 minutes is filtered filtrate for later use; Filtering residue adds water, and heating was boiled 30 minutes for the second time, refiltered filtrate for later use; Filtering residue adds water again, and heated and boiled is 40 minutes for the third time, filters; Three filtratings are lumped together, and heating is concentrated into pasty state, puts into baking oven, is controlled at 80 ℃, dries postcooling, and mixing with Mel is twisted into slice, processes honey refining ball and wax seal packing.
8. the Chinese medicine composition of each said treatment herpes zoster among the claim 1-4 is characterized in that the dosage form of said Chinese medicine composition is a capsule, and its preparation method is:
Said crude drug is added the ethanol of 10 times of amounts of weight, heating and refluxing extraction 3 times, each 2 hours, 3 extracting solution are merged, decompression recycling ethanol, and to be concentrated into liquor strength be 0.5g crude drug/mL is behind the sucking filtration, when the relative density of filtrating is 20 ℃ 1.08; Said filtrate flow is the adsorption resin column of 10L through volume, uses the deionized water or the distilled water eluting of 10 times of resin column volumes afterwards, 95% ethanol elution of 5 times of resin column volumes of reuse; Collect ethanol elution; Remove alcohol solvent, obtain component medicated powder, incapsulate and be made as capsule.
9. the Chinese medicine composition of each said treatment herpes zoster among the claim 1-4 is characterized in that the dosage form of said Chinese medicine composition is a tablet, and its preparation method is:
Said each crude drug chopping is joined in the multi-function extractor, and the adding ratio of weight and number is that 3000 parts water logging was steeped 30~40 minutes, decocts after 1.5 hours, and decoction liquor is subsequent use for the first time in taking-up; Medicinal residues adding ratio of weight and number is after 3000 parts decocting boils 1 hour, to take out decoction liquor for the second time, aforementioned twice decoction liquor is merged filter; It is 1000 parts solution that filtrate decompression is concentrated into ratio of weight and number, staticly settles 24~36 hours, draws supernatant; Add starch after being heated to 40~50 ℃, heating is concentrated into pasty state, puts into baking oven; Be controlled at 80 ℃, oven dry postcooling, film-making, drying, molding, packing.
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Publication number Priority date Publication date Assignee Title
CN102988692A (en) * 2012-11-13 2013-03-27 黄文珍 Traditional Chinese medicine composition for treating herpes zoster and preparation method thereof
CN103656361A (en) * 2013-12-10 2014-03-26 张朝兰 Medicine used for treating herpes zoster, and preparation method thereof
CN106138251A (en) * 2016-08-25 2016-11-23 颜喜贤 A kind of Chinese medicine composition treating herpes zoster
CN108126084A (en) * 2018-01-11 2018-06-08 孙鲁娜 A kind of Chinese medicine composition for treating flat wart and its application in dept. of dermatology
CN111904991A (en) * 2020-09-24 2020-11-10 郑州铭泽生物科技有限公司 Traditional Chinese medicine composition for treating herpes zoster and preparation method thereof

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CN100571731C (en) * 2007-04-16 2009-12-23 北京艺信堂医药研究所 A kind of Chinese medicine decoction for the treatment of herpes zoster
CN101703732B (en) * 2009-09-29 2011-06-08 李家娣 Chinese medicinal ointment for treating herpes zoster and preparation method thereof
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EP0568001A2 (en) * 1992-04-27 1993-11-03 Showa Shell Sekiyu Kabushiki Kaisha Antiviral agent containing crude drug
CN100571731C (en) * 2007-04-16 2009-12-23 北京艺信堂医药研究所 A kind of Chinese medicine decoction for the treatment of herpes zoster
CN101129881A (en) * 2007-09-24 2008-02-27 北京艺信堂医药研究所 Traditional Chinese medicine composition for treating breast zoster
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CN101703732B (en) * 2009-09-29 2011-06-08 李家娣 Chinese medicinal ointment for treating herpes zoster and preparation method thereof

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102988692A (en) * 2012-11-13 2013-03-27 黄文珍 Traditional Chinese medicine composition for treating herpes zoster and preparation method thereof
CN102988692B (en) * 2012-11-13 2014-12-17 黄文珍 Traditional Chinese medicine composition for treating herpes zoster and preparation method thereof
CN103656361A (en) * 2013-12-10 2014-03-26 张朝兰 Medicine used for treating herpes zoster, and preparation method thereof
CN103656361B (en) * 2013-12-10 2015-06-03 张朝兰 Medicine used for treating herpes zoster, and preparation method thereof
CN106138251A (en) * 2016-08-25 2016-11-23 颜喜贤 A kind of Chinese medicine composition treating herpes zoster
CN108126084A (en) * 2018-01-11 2018-06-08 孙鲁娜 A kind of Chinese medicine composition for treating flat wart and its application in dept. of dermatology
CN111904991A (en) * 2020-09-24 2020-11-10 郑州铭泽生物科技有限公司 Traditional Chinese medicine composition for treating herpes zoster and preparation method thereof

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