CN102429747A - Atlas fusion prosthesis - Google Patents
Atlas fusion prosthesis Download PDFInfo
- Publication number
- CN102429747A CN102429747A CN2011104485192A CN201110448519A CN102429747A CN 102429747 A CN102429747 A CN 102429747A CN 2011104485192 A CN2011104485192 A CN 2011104485192A CN 201110448519 A CN201110448519 A CN 201110448519A CN 102429747 A CN102429747 A CN 102429747A
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- atlas
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- prosthese
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- 230000004927 fusion Effects 0.000 title claims abstract description 34
- 210000000988 bone and bone Anatomy 0.000 claims abstract description 29
- 210000000103 occipital bone Anatomy 0.000 claims abstract description 16
- 230000035479 physiological effects, processes and functions Effects 0.000 claims description 22
- 238000000034 method Methods 0.000 claims description 11
- 229910052751 metal Inorganic materials 0.000 claims description 6
- 239000002184 metal Substances 0.000 claims description 6
- 230000008569 process Effects 0.000 claims description 5
- 239000011247 coating layer Substances 0.000 claims description 4
- 229910052588 hydroxylapatite Inorganic materials 0.000 claims description 4
- XYJRXVWERLGGKC-UHFFFAOYSA-D pentacalcium;hydroxide;triphosphate Chemical compound [OH-].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O XYJRXVWERLGGKC-UHFFFAOYSA-D 0.000 claims description 4
- 239000011148 porous material Substances 0.000 claims description 4
- 239000011248 coating agent Substances 0.000 claims description 3
- 238000000576 coating method Methods 0.000 claims description 3
- 230000002787 reinforcement Effects 0.000 claims description 3
- 239000003351 stiffener Substances 0.000 claims description 3
- 230000002980 postoperative effect Effects 0.000 abstract description 3
- 230000008901 benefit Effects 0.000 abstract description 2
- 238000011084 recovery Methods 0.000 abstract description 2
- 238000013499 data model Methods 0.000 description 6
- 238000010894 electron beam technology Methods 0.000 description 6
- 239000007943 implant Substances 0.000 description 6
- 239000008187 granular material Substances 0.000 description 4
- 210000004409 osteocyte Anatomy 0.000 description 4
- 239000000843 powder Substances 0.000 description 4
- 238000007493 shaping process Methods 0.000 description 4
- RTAQQCXQSZGOHL-UHFFFAOYSA-N Titanium Chemical compound [Ti] RTAQQCXQSZGOHL-UHFFFAOYSA-N 0.000 description 3
- 238000013461 design Methods 0.000 description 3
- 238000005516 engineering process Methods 0.000 description 3
- 239000010936 titanium Substances 0.000 description 3
- 229910052719 titanium Inorganic materials 0.000 description 3
- 238000010276 construction Methods 0.000 description 2
- 230000000694 effects Effects 0.000 description 2
- 238000002513 implantation Methods 0.000 description 2
- 230000007774 longterm Effects 0.000 description 2
- 238000010309 melting process Methods 0.000 description 2
- 238000012545 processing Methods 0.000 description 2
- 238000003672 processing method Methods 0.000 description 2
- 210000001519 tissue Anatomy 0.000 description 2
- 206010010356 Congenital anomaly Diseases 0.000 description 1
- 206010028980 Neoplasm Diseases 0.000 description 1
- 206010041591 Spinal osteoarthritis Diseases 0.000 description 1
- 206010052428 Wound Diseases 0.000 description 1
- 208000027418 Wounds and injury Diseases 0.000 description 1
- 210000003484 anatomy Anatomy 0.000 description 1
- 238000013459 approach Methods 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 208000036319 cervical spondylosis Diseases 0.000 description 1
- 238000005520 cutting process Methods 0.000 description 1
- 230000008034 disappearance Effects 0.000 description 1
- 238000005553 drilling Methods 0.000 description 1
- 238000004070 electrodeposition Methods 0.000 description 1
- 238000000605 extraction Methods 0.000 description 1
- 230000009931 harmful effect Effects 0.000 description 1
- 230000008676 import Effects 0.000 description 1
- 230000006872 improvement Effects 0.000 description 1
- 230000001939 inductive effect Effects 0.000 description 1
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- 239000010410 layer Substances 0.000 description 1
- 238000003754 machining Methods 0.000 description 1
- 230000036244 malformation Effects 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 238000000465 moulding Methods 0.000 description 1
- 231100000915 pathological change Toxicity 0.000 description 1
- 230000036285 pathological change Effects 0.000 description 1
- 238000007750 plasma spraying Methods 0.000 description 1
- 238000012797 qualification Methods 0.000 description 1
- 206010039073 rheumatoid arthritis Diseases 0.000 description 1
- 239000002356 single layer Substances 0.000 description 1
- 238000005245 sintering Methods 0.000 description 1
- 210000003625 skull Anatomy 0.000 description 1
- 210000004872 soft tissue Anatomy 0.000 description 1
- 208000005801 spondylosis Diseases 0.000 description 1
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Images
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2/44—Joints for the spine, e.g. vertebrae, spinal discs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2002/30001—Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
Landscapes
- Health & Medical Sciences (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Transplantation (AREA)
- Neurology (AREA)
- Vascular Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Prostheses (AREA)
Abstract
The present invention provides an atlas fusion prosthesis, which is arranged between an occipital bone and an axis to replace a physiological atlas, comprising: a prosthesis body; the upper joint fusion surface is arranged at the upper part of the prosthesis main body and is used for being jointed with the occipital condyle joint surface of the occipital bone; the lower joint fusion surface is arranged at the lower part of the prosthesis main body and is used for being jointed with the upper joint surface of the axis. The main advantages of the invention are that the atlas prosthesis with a fusion surface matched with the occipital bone and the epistropheus is implanted to replace the physiological atlas, so that the function of the atlas can be quickly recovered, the bone fusion is promoted, the purpose of reconstructing the cervical vertebra to be stable is achieved, and the postoperative recovery is facilitated.
Description
Technical field
The present invention relates to the orthopaedics implant field, particularly a kind of atlas of alternative nature articulatio atlantoepistrophica merges prosthese.
Background technology
Articulatio atlantoepistrophica is the very special and important spinal structure that connects skull and spinal column.But atlas damage that causes owing to pathological changes such as a variety of causes such as wound, tumor, congenital malformation, tuberculosis, rheumatoid arthritis and disappearance have in orthopaedics therapy the time and run into.Because articulatio atlantoepistrophica position of living in and anatomical structure thereof are extremely special, conventional cervical vertebral fusion cage can't be suitable for, and does not still implant replacement scheme to the prosthese of atlas at present.Can only adopt as the case may be from body or allograph bone by the doctor in clinical temporarily and carry out bone grafting or implant the way of transforming titanium cage or titanium net and carry out bone and merge; This technology needs the head and neck shoulder of long period fixing until merging fully after operation, brings very big inconvenience for patient's life.
Summary of the invention
The present invention provides a kind of atlas to merge prosthese, and is slow with the fusion that implantation titanium cage causes to solve existing bone grafting, needs long-time fixed problem.
The present invention realizes through following technical scheme: a kind of atlas merges prosthese, is arranged between occipital bone and the dentata to substitute the physiology atlas, comprising: prosthetic main; Upper joint merges face, is arranged on prosthetic main top, is used for fitting with the occipital condyle articular surface of occipital bone; Hypozygal merges face, is arranged on the prosthetic main bottom, is used for fitting with the superior articular surface of dentata.
Further, comprise also that the prominent concave surface that combines of tooth is arranged on the side of prosthetic main, and is consistent with the prominent concave surface face shape that combines of the tooth of physiology atlas, the tooth that is used to hold dentata is dashed forward.
Further, the surface of upper joint fusion face, hypozygal fusion face and the prominent faying face of tooth has microcellular structure.
Further, microcellular structure is the multidirectional micro hole structure that is interconnected, and pore diameter is 100 μ m to 1800 μ m.
Further, prosthetic main is the microcellular structure that medical metal is processed.
Further, do not comprise transverse process and the corresponding bulge-structure of cantle with the physiology atlas in the shape of prosthetic main.
Further, prosthetic main is concordant with physiology atlas dead ahead physiology surface or be positioned at relatively in this physiology atlas dead ahead physiology surface on the surface of dead ahead.
Further, the prosthetic main upper end is provided with the screwing hole, and the prosthetic main lower end is provided with lower screw hole.
Further, the occupy-place height of atlas fusion prosthese is consistent with the physiology atlas.
Further, atlas merges prosthese to extending below until alternative dentata or third cervical vertebra or more cervical vertebral body, and the cervical vertebral body superior articular surface that hypozygal merges below face and the atlas fusion prosthese is fitted.
Further, prosthetic main is provided with a plurality of bone graftings hole.
Further, the aperture in bone grafting hole is 2mm to 30mm.
Further, the surface of prosthetic main and/or set inside have reinforcement or stiffener.
Further, the whole or local coating of the outer surface of prosthetic main and/or inner surface has hydroxyapatite coating layer.
Through technique scheme, major advantage of the present invention is to implant the atlas prosthese with the fusion face that agrees with occipital bone and dentata; Substitute the physiology atlas, can recover the function of atlas very soon, promote bone to merge; Reach and rebuild the stable purpose of cervical vertebra, help post-operative recovery.
Description of drawings
The accompanying drawing that constitutes a part of the present invention is used to provide further understanding of the present invention, and illustrative examples of the present invention and explanation thereof are used to explain the present invention, does not constitute improper qualification of the present invention.In the accompanying drawings:
Fig. 1 shows the schematic perspective view that atlas of the present invention merges prosthese;
What Fig. 2 showed that atlas of the present invention merges prosthese cooperates sketch map with bone structure up and down;
Fig. 3 shows atlas of the present invention and merges the connection status sketch map that prosthese cooperates with the bottom dentata; And
Fig. 4 shows the view that atlas of the present invention merges the extension lengthening embodiment of prosthese.
The specific embodiment
Below in conjunction with accompanying drawing embodiments of the invention are elaborated, but the multitude of different ways that the present invention can be defined by the claims and cover is implemented.
The atlas that one embodiment of the present of invention have been shown among Fig. 1 merges prosthese, comprising: atlas merges prosthetic main 10, on atlas fusion prosthetic main 10, is provided with upper joint fusion face 20 and merges face with hypozygal.The joint fusion face is to be processed by Digit Control Machine Tool after extracting the curved surface data of occipital condyle articular surface and dentata superior articular surface of occipital bone bottom respectively up and down; Also can utilize rapid shaping techniques such as laser sintered or high-power electron beam fusion to build surface with curved surface height match characteristic; Atlas fusion prosthese upper joint fusion face 20 is built according to the occipital condyle articular surface data of occipital bone and is well identical with the occipital condyle articular surface of occipital bone, and atlas merges prosthese hypozygal fusion face and well coincide according to the construction of dentata superior articular surface data and with the dentata superior articular surface.Atlas merges prosthese front inner side and is provided with the prominent concave surface 30 that combines of the tooth that can hold dens axis consistent with proatlas dental fovea shape.The prominent combination of joint fusion face and tooth concave surface 30 surfaces are microcellular structure; This microcellular structure is a kind of multidirectional micro hole structure that is interconnected; Pore diameter is 100 μ m～1800 μ m; This hole helps osteocyte creeps and grows into, and the postoperative atlas merges the prominent faying face of prosthese tooth will bone be taken place with dens axis and merge to reach steady in a long-term.
As shown in Figure 2; Needs from operative approach; This atlas merges prosthese can not keep transverse process, cantle structure; This atlas fusion prosthese keeps basically identical with the former physiology atlas of patient vertebral body dimensionally except that the design of necessary function property changes, and its overall occupy-place height was consistent with former physiology articulatio atlantoepistrophica after atlas merged the prosthese implant into body, kept original location status to guarantee the cervical vertebra surrounding tissue.Said dentata merges prosthese, and to be equipped with the joint fusion face well identical with the superior articular surface 51 of the occipital condyle articular surface of occipital bone 40 and dentata 50 respectively at two ends up and down; Said atlas merges prosthese and is provided with bone grafting hole 80 and can holds from body or allograph bone piece and osseous granules, is implanted in this bone grafting hole before the art or in the art can play to induce osteocyte to creep and grow into osseous granules from body or allograph bone piece to promote the effect of bone fusion; Said atlas merge prosthese in art, be directly fixed on below the occipital bone 40 with dentata 50 above to substitute atlas; Said atlas merges prosthese and is respectively equipped with screw hole 70,90 fixedly to carry out stablizing in early days through screw 60 with occipital bone 40 and dentata 50 in two ends up and down, treats can reach after the bone fusion is accomplished and rebuilds the stable purpose of cervical vertebra.
As shown in Figure 3, it is said zero incisura of medical circle that said atlas fusion prosthese its dead ahead surface after implantation does not protrude in proatlas dead ahead physiology surface, therefore the various soft tissue anatomical positions in atlas the place ahead is not had any harmful effect.
As shown in Figure 4; Said atlas merges the screwing hole 70 that the prosthese anterior arch left and right sides is provided with 1～2 oblique back upper place; Said atlas merges the prosthese lower end corresponding to the lower screw hole 90 that also is provided with 1～3 oblique back lower place on the position of dentata superior articular surface, in the art through screw 60 fixing with reach and occipital bone 40 and dentata 50 between early stage stable.Preferably; As shown in Figure 4; When patient's atlas, dentata or more cervical vertebras stage all need be substituted by prosthese, said atlas merges prosthetic main 1 can be according to the individual patients needs to extending below lengthening to contain alternative dentata and even third cervical vertebra until more cervical vertebral body sections.Said atlas merged prosthese and will be connected with the 3rd or other sections cervical vertebral bodies and fix this moment, and its fixing and fusing mode is with above-mentioned dock fixed mode with dentata identical.
Preferably, said atlas merges prosthetic main 1 and is provided with some bone graftings hole 80, and 80 apertures, bone grafting hole are 2mm～30mm, connects each other between the bone grafting hole or pass through micropore to connect said micropore size 100 μ m～1800 μ m.This bone grafting hole can hold from body or allograph bone piece and osseous granules, is implanted in this bone grafting hole before the art or in the art can play to induce osteocyte to creep and grow into osseous granules from body or allograph bone piece to promote the effect of bone fusion.
Preferably, it is the microcellular structure that medical metal is processed that said atlas merges prosthetic main, and the surface and the internal void of this microcellular structure connect each other, the pore diameter 100 μ m～1800 μ m of said microcellular structure, so it has good biocompatibility.
Preferably, said atlas fusion prosthetic main surface and/or set inside have reinforcement or stiffener.
Preferably, said atlas merges the body surfaces of prosthese and/or inner whole or local coating has hydroxyapatite coating layer, has the function of inducing the osteocyte growth.The processing method of this hydroxyapatite coating layer is: adopt conventional plasma spraying method or electrochemical deposition method and sintering process to form.
The processing method that atlas according to the invention merges prosthese is: obtain the tomoscan data such as patient's cervical vertebra position CT/MRI/UCT → in computer, set up three-dimensional data model → the extractions atlas model at cervical spondylosis position and the design of making amendment and generate atlas and merge prosthese three-dimensional data model → merge prosthese three-dimensional data model stimulated replacement physiology atlas with inspection and verify design → machine-shaping with atlas.
According to present process technology two comparatively ideal machining paths are arranged:
A. adopt numerical control machine tool to carry out machine-shaping, use methods such as spark machined, chemical attack, machine drilling cutting, high-temperature plasma metal spraying to bore then and mill processing and apply out needed bone grafting hole, screw hole and microcellular structure according to the processor that the atlas that in computer, generates merges prosthese data transaction one-tenth;
B. utilize laser sintered or rapid shaping technique melt molding such as high-power electron beam fusion, concrete grammar is following:
A) use professional software that the atlas fusion prosthese three-dimensional data model of design-build in computer is carried out layering, to obtain the outline data of a series of monolayer slices;
B) import above-mentioned serial synusia data to laser or high-power electron beam rapid forming equipment;
The medical metal powder of floor height respective thickness when c) in laser or high-power electron beam rapid forming equipment processing cabin, laying with aforementioned three-dimensional data model layering;
D) by computer controlled controlling laser beam or high-power electron beam the medical metal powder is scanned and selectively the fusing;
E) repeat aforementioned laying powder, scanning fusing step so that each layer is selected the mutual clinkering one-tenth of the material of fusing integral body;
F) remove the atlas fusion prosthese that not fused powder can obtain required shape and structure behind the melting process of the whole aspects of completion;
G) owing to needed entity, bone grafting hole, screw hole, micropore or the like structure has been designed in the lump in data file when atlas merges the prosthese three-dimensional data model building, therefore above-mentioned various structures in laser sintered or high-power electron beam melting process with disposable completion manufacturing.
Merge prosthese according to atlas of the present invention, have following beneficial effect:
Be consistent with the former physiology atlas of patient vertebral body dimensionally, guarantee that the cervical vertebra surrounding tissue keeps original location status; Atlas merges prosthetic joint and merges face according to occipital bone and dentata articular surface data construction and well identical with its articular surface; To dash forward good chimeric with the tooth of dentata behind the prosthese implant into body and form bone and merge to reach steady in a long-term.
The above is merely the preferred embodiments of the present invention, is not limited to the present invention, and for a person skilled in the art, the present invention can have various changes and variation.All within spirit of the present invention and principle, any modification of being done, be equal to replacement, improvement etc., all should be included within protection scope of the present invention.
Claims (14)
1. an atlas merges prosthese, is arranged between occipital bone (40) and the dentata (50) with alternative physiology atlas, it is characterized in that, comprising:
Prosthetic main (10);
Upper joint merges face (20), is arranged on said prosthetic main (10) top, is used for fitting with the occipital condyle articular surface of said occipital bone (40);
Hypozygal merges face, is arranged on said prosthetic main (10) bottom, is used for fitting with the superior articular surface (51) of said dentata (50).
2. atlas according to claim 1 merges prosthese, it is characterized in that, also comprises; The prominent concave surface (30) that combines of tooth; Be arranged on the side surface of said prosthetic main (10), consistent with the prominent concave that combines of the tooth of said physiology atlas, the tooth that is used to hold said dentata (50) is dashed forward.
3. atlas according to claim 2 merges prosthese, it is characterized in that, the surface that said upper joint merges face (20), said hypozygal fusion face and the prominent faying face (30) of said tooth has microcellular structure.
4. atlas according to claim 3 merges prosthese, it is characterized in that said microcellular structure is the multidirectional micro hole structure that is interconnected, and pore diameter is 100 μ m to 1800 μ m.
5. atlas according to claim 1 merges prosthese, it is characterized in that the microcellular structure that said prosthetic main (10) is processed for medical metal.
6. atlas according to claim 1 merges prosthese, it is characterized in that, does not comprise transverse process and the corresponding bulge-structure of cantle with said physiology atlas in the shape of said prosthetic main (10).
7. atlas according to claim 1 merges prosthese, it is characterized in that, said prosthetic main (10) is surperficial concordant with said physiology atlas dead ahead physiology or be positioned at relatively in the said physiology atlas dead ahead physiology surface on the surface of dead ahead.
8. atlas according to claim 1 merges prosthese, it is characterized in that, said prosthetic main (10) upper end is provided with screwing hole (70), and said prosthetic main (10) lower end is provided with lower screw hole (90).
9. atlas according to claim 1 merges prosthese, it is characterized in that, the occupy-place height of said atlas fusion prosthese is consistent with said physiology atlas.
10. atlas according to claim 1 merges prosthese; It is characterized in that; Said atlas merges prosthese to extending below until alternative said dentata (50) or third cervical vertebra or more cervical vertebral body, and the cervical vertebral body superior articular surface that said hypozygal merges below face and the said atlas fusion prosthese is fitted.
11. atlas according to claim 1 merges prosthese, it is characterized in that said prosthetic main (10) is provided with a plurality of bone graftings hole (80).
12. atlas according to claim 11 merges prosthese, it is characterized in that the aperture in said bone grafting hole (80) is 2mm to 30mm.
13. atlas according to claim 1 merges prosthese, it is characterized in that the surface and/or the set inside of said prosthetic main (10) have reinforcement or stiffener.
14. atlas according to claim 1 merges prosthese, it is characterized in that the outer surface of said prosthetic main (10) and/or the whole or local coating of inner surface have hydroxyapatite coating layer.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2011104485192A CN102429747A (en) | 2011-12-28 | 2011-12-28 | Atlas fusion prosthesis |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2011104485192A CN102429747A (en) | 2011-12-28 | 2011-12-28 | Atlas fusion prosthesis |
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| Publication Number | Publication Date |
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| CN102429747A true CN102429747A (en) | 2012-05-02 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN2011104485192A Pending CN102429747A (en) | 2011-12-28 | 2011-12-28 | Atlas fusion prosthesis |
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Cited By (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2013060168A1 (en) * | 2011-10-24 | 2013-05-02 | 北京爱康宜诚医疗器材股份有限公司 | Fusion prosthesis |
| CN104619279A (en) * | 2012-09-12 | 2015-05-13 | 新特斯有限责任公司 | Method for producing patient-specific plate |
| US9707044B2 (en) | 2012-05-03 | 2017-07-18 | DePuy Synthes Products, Inc. | Surgical guides from scanned implant data |
| CN108158699A (en) * | 2018-02-08 | 2018-06-15 | 中国人民解放军第二军医大学第二附属医院 | Upper cervical spine bearing-type rebuilds prosthese |
| CN109077835A (en) * | 2018-10-26 | 2018-12-25 | 北京爱康宜诚医疗器材有限公司 | Centrum prosthese |
| CN110664521A (en) * | 2019-11-04 | 2020-01-10 | 广州华钛三维材料制造有限公司 | Prosthesis is implanted to dentata |
| CN110916783A (en) * | 2019-12-05 | 2020-03-27 | 广州华钛三维材料制造有限公司 | Dentata centrum fixing and fusing device |
| CN114129308A (en) * | 2021-11-15 | 2022-03-04 | 中国人民解放军空军军医大学 | 3D prints fixed integration back way neck pillow and fuses false body |
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| WO2013060168A1 (en) * | 2011-10-24 | 2013-05-02 | 北京爱康宜诚医疗器材股份有限公司 | Fusion prosthesis |
| US9707044B2 (en) | 2012-05-03 | 2017-07-18 | DePuy Synthes Products, Inc. | Surgical guides from scanned implant data |
| US10467356B2 (en) | 2012-05-03 | 2019-11-05 | DePuy Synthes Products, Inc. | Surgical guide with cut resistant insert |
| CN104619279A (en) * | 2012-09-12 | 2015-05-13 | 新特斯有限责任公司 | Method for producing patient-specific plate |
| CN104619279B (en) * | 2012-09-12 | 2018-06-01 | 新特斯有限责任公司 | For manufacturing the method for patient's personality board |
| US10548668B2 (en) | 2012-09-12 | 2020-02-04 | DePuy Synthes Products, Inc. | Method for producing patient-specific plate |
| CN108158699A (en) * | 2018-02-08 | 2018-06-15 | 中国人民解放军第二军医大学第二附属医院 | Upper cervical spine bearing-type rebuilds prosthese |
| CN109077835A (en) * | 2018-10-26 | 2018-12-25 | 北京爱康宜诚医疗器材有限公司 | Centrum prosthese |
| CN110664521A (en) * | 2019-11-04 | 2020-01-10 | 广州华钛三维材料制造有限公司 | Prosthesis is implanted to dentata |
| CN110916783A (en) * | 2019-12-05 | 2020-03-27 | 广州华钛三维材料制造有限公司 | Dentata centrum fixing and fusing device |
| CN114129308A (en) * | 2021-11-15 | 2022-03-04 | 中国人民解放军空军军医大学 | 3D prints fixed integration back way neck pillow and fuses false body |
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