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CN102316885A - 通过奥利万星给药抑制艰难梭菌的方法 - Google Patents

通过奥利万星给药抑制艰难梭菌的方法 Download PDF

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Publication number
CN102316885A
CN102316885A CN2008801102448A CN200880110244A CN102316885A CN 102316885 A CN102316885 A CN 102316885A CN 2008801102448 A CN2008801102448 A CN 2008801102448A CN 200880110244 A CN200880110244 A CN 200880110244A CN 102316885 A CN102316885 A CN 102316885A
Authority
CN
China
Prior art keywords
clostridium difficile
glycopeptide antibiotics
spore
difficile
oritavancin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN2008801102448A
Other languages
English (en)
Chinese (zh)
Inventor
M·H·威尔科克斯
S·拜恩斯
D·勒乌
T·R·帕尔
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Medicines Co
Original Assignee
Medicines Co
Targanta Therapeutics Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Medicines Co, Targanta Therapeutics Corp filed Critical Medicines Co
Publication of CN102316885A publication Critical patent/CN102316885A/zh
Pending legal-status Critical Current

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/14Peptides containing saccharide radicals; Derivatives thereof, e.g. bleomycin, phleomycin, muramylpeptides or vancomycin
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/90Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having two or more relevant hetero rings, condensed among themselves or with a common carbocyclic ring system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Plant Pathology (AREA)
  • Pest Control & Pesticides (AREA)
  • Agronomy & Crop Science (AREA)
  • Dentistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Environmental Sciences (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CN2008801102448A 2007-09-12 2008-09-11 通过奥利万星给药抑制艰难梭菌的方法 Pending CN102316885A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US97176607P 2007-09-12 2007-09-12
US60/971766 2007-09-12
PCT/US2008/075949 WO2009036121A1 (en) 2007-09-12 2008-09-11 Method of inhibiting clostridium difficile by administration of oritavancin

Publications (1)

Publication Number Publication Date
CN102316885A true CN102316885A (zh) 2012-01-11

Family

ID=40452464

Family Applications (1)

Application Number Title Priority Date Filing Date
CN2008801102448A Pending CN102316885A (zh) 2007-09-12 2008-09-11 通过奥利万星给药抑制艰难梭菌的方法

Country Status (9)

Country Link
US (3) US8518873B2 (ru)
EP (1) EP2195004B1 (ru)
JP (1) JP5591112B2 (ru)
CN (1) CN102316885A (ru)
AU (1) AU2008298987B2 (ru)
CA (1) CA2699550C (ru)
EA (1) EA017564B1 (ru)
ES (1) ES2535928T3 (ru)
WO (1) WO2009036121A1 (ru)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109071607A (zh) * 2016-04-29 2018-12-21 中国科学院上海药物研究所 一类万古霉素衍生物、其制备方法、药物组合物和用途
CN115443286A (zh) * 2020-04-22 2022-12-06 尹特荣生物科技株式会社 对艰难梭菌具有溶菌活性的抗菌蛋白cdl200

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CA2699550C (en) * 2007-09-12 2020-08-18 Targanta Therapeutics Corp. Method of inhibiting clostridium difficile by administration of oritavancin
WO2009126502A2 (en) * 2008-04-08 2009-10-15 Targanta Therapeutics Corp. Methods of inhibiting and treating biofilms using glycopeptide antibiotics
BRPI1014767A2 (pt) * 2009-04-28 2016-04-19 Targanta Therapeutics Corp métodos de tratamento de infecções bacterianas usando oritavancina
JP5986416B2 (ja) * 2012-04-11 2016-09-06 花王株式会社 皮膚外用剤
US8906668B2 (en) 2012-11-23 2014-12-09 Seres Health, Inc. Synergistic bacterial compositions and methods of production and use thereof
JP6506173B2 (ja) 2012-11-23 2019-04-24 セレス セラピューティクス インコーポレイテッド 相乗的細菌組成物並びにその生成及び使用の方法
CN110917220A (zh) 2013-02-04 2020-03-27 赛里斯治疗公司 治疗组合物及其使用方法
US10973861B2 (en) 2013-02-04 2021-04-13 Seres Therapeutics, Inc. Compositions and methods
EP2967077A4 (en) 2013-03-15 2016-09-14 Seres Therapeutics Inc NETWORK-BASED MICROBIAL COMPOSITIONS AND METHOD
CN116370507A (zh) 2013-11-25 2023-07-04 赛里斯治疗公司 协同细菌组合物以及其制造方法和用途
EP3082431A4 (en) 2013-12-16 2017-11-15 Seres Therapeutics, Inc. Bacterial compositions and methods of use thereof for treatment of immune system disorders
JP6553074B2 (ja) * 2014-10-14 2019-07-31 アーゼッド・エレクトロニック・マテリアルズ(ルクセンブルグ)ソシエテ・ア・レスポンサビリテ・リミテ レジストパターン処理用組成物およびそれを用いたパターン形成方法
GB201509326D0 (en) 2015-05-29 2015-07-15 Antibio Tx Aps Novel use
MX2018009948A (es) 2016-02-18 2018-12-06 Melinta Therapeutics Inc Formulaciones de oritavancina.
EP3454883A1 (en) 2016-05-09 2019-03-20 Xellia Pharmaceuticals ApS Stabilized glycopeptide antibiotic formulations
KR20240110077A (ko) 2017-08-14 2024-07-12 세레스 테라퓨틱스, 인코포레이티드 담즙정체성 질환 치료를 위한 조성물 및 방법
CN111432826A (zh) 2017-10-30 2020-07-17 赛里斯治疗公司 用于治疗抗生素耐药性的组合物和方法
US20220096510A1 (en) * 2018-08-17 2022-03-31 Universidad Andrés Bello Method and pharmacological composition for the prevention of recurrent infections caused by clostridium difficile

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1918172A (zh) * 2003-12-23 2007-02-21 活跃生物工艺学公司 利福霉素类似物及其用途

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JP2961184B2 (ja) * 1990-05-07 1999-10-12 ミヤリサン株式会社 クロストリジウム・ディフィシル下痢症および偽膜性大腸炎の予防ならびに治療用医薬組成物
GB0212622D0 (en) * 2002-05-31 2002-07-10 Natural Technologies Group Ltd Bacterial transforming agent
CA2488803C (en) * 2002-06-06 2013-08-13 Vicuron Pharmaceuticals Inc. Use of ramoplanin to treat diseases associated with the use of antibiotics
CA2495144A1 (en) * 2002-08-29 2004-03-11 Activbiotics, Inc. Methods and reagents for treating infections of clostridium difficile and diseases associated therewith
US20070238652A1 (en) * 2006-02-08 2007-10-11 Biosynexus Incorporated Neutralization of bacterial spores
GB0714030D0 (en) * 2007-07-18 2007-08-29 Novacta Biosystems Ltd The use of type-B lantibiotic-based compounds having antimicrobial activity
CA2699550C (en) * 2007-09-12 2020-08-18 Targanta Therapeutics Corp. Method of inhibiting clostridium difficile by administration of oritavancin

Patent Citations (1)

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Publication number Priority date Publication date Assignee Title
CN1918172A (zh) * 2003-12-23 2007-02-21 活跃生物工艺学公司 利福霉素类似物及其用途

Non-Patent Citations (7)

* Cited by examiner, † Cited by third party
Title
ANIL K. GOEL ET AL: "inhibitory effect of penicillin on spore-specific functions in Bacillus polymyxa 2459", 《J.BIOSCI.》 *
SILLERSTROM, E. ET CL: "in vitro activity of LY 333328 against anaerobic gram-positive bacteria", 《JOURNAL OF CHEMOTHERAPY》 *
W.C.CHAN ET AL: "structure-activity relationships in the peptide antibiotic nisinL:role of dehydroalanine 5", 《APPLIED AND ENVIRONMENTAL MICROBIOLOGY》 *
WARD, KE ET CL.: "oritavancin-an investigational glycopeptides antibiotic", 《EXPERT OPINION ON INVESTIGATIONAL DRUGS》 *
WEI LIU ET AL: "the antimicrobial effect of a structural variant of subtilin against outgrowing bacillus cereus t spores and vegetative cells occus by different mechanisms", 《APPLIED AND ENVIRONMENTAL MICROBIOLOGY》 *
杨霖: "厌氧芽孢杆菌属", 《中国乡村医生杂志》 *
谭玲等: "新型糖肽类抗生素奥利万星", 《中国新药杂志》 *

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109071607A (zh) * 2016-04-29 2018-12-21 中国科学院上海药物研究所 一类万古霉素衍生物、其制备方法、药物组合物和用途
CN109071607B (zh) * 2016-04-29 2022-09-27 中国科学院上海药物研究所 一类万古霉素衍生物、其制备方法、药物组合物和用途
CN115443286A (zh) * 2020-04-22 2022-12-06 尹特荣生物科技株式会社 对艰难梭菌具有溶菌活性的抗菌蛋白cdl200
CN115443286B (zh) * 2020-04-22 2023-08-29 尹特荣生物科技株式会社 对艰难梭菌具有溶菌活性的抗菌蛋白cdl200

Also Published As

Publication number Publication date
EP2195004A1 (en) 2010-06-16
US20100311646A1 (en) 2010-12-09
EA017564B1 (ru) 2013-01-30
AU2008298987B2 (en) 2013-12-05
US20130310308A1 (en) 2013-11-21
JP5591112B2 (ja) 2014-09-17
AU2008298987A1 (en) 2009-03-19
CA2699550C (en) 2020-08-18
US8629100B2 (en) 2014-01-14
EA201000383A1 (ru) 2010-10-29
CA2699550A1 (en) 2009-03-19
ES2535928T3 (es) 2015-05-19
JP2010539179A (ja) 2010-12-16
EP2195004B1 (en) 2015-04-01
EP2195004A4 (en) 2011-12-28
BRPI0816662A2 (pt) 2017-06-13
US20140100157A1 (en) 2014-04-10
WO2009036121A1 (en) 2009-03-19
US8518873B2 (en) 2013-08-27
US9220749B2 (en) 2015-12-29

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Free format text: FORMER OWNER: MEDICINES CORP.

Effective date: 20131119

Owner name: MEDICINES CORP.

Free format text: FORMER OWNER: TARGANTA THERAPEUTICS CORP.

Effective date: 20131119

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Address after: new jersey

Applicant after: The Medicines Company

Address before: new jersey

Applicant before: Targanta Therapeutics Corp.

Applicant before: The Medicines Company

RJ01 Rejection of invention patent application after publication

Application publication date: 20120111

RJ01 Rejection of invention patent application after publication