CN101676275B - 一种富马酸喹硫平的制备方法 - Google Patents
一种富马酸喹硫平的制备方法 Download PDFInfo
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- CN101676275B CN101676275B CN200810222433.6A CN200810222433A CN101676275B CN 101676275 B CN101676275 B CN 101676275B CN 200810222433 A CN200810222433 A CN 200810222433A CN 101676275 B CN101676275 B CN 101676275B
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- quetiapine fumarate
- ethanol
- dibenzo
- ethyl acetate
- chloroethoxy
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CN200810222433.6A CN101676275B (zh) | 2008-09-17 | 2008-09-17 | 一种富马酸喹硫平的制备方法 |
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CN200810222433.6A CN101676275B (zh) | 2008-09-17 | 2008-09-17 | 一种富马酸喹硫平的制备方法 |
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CN101676275A CN101676275A (zh) | 2010-03-24 |
CN101676275B true CN101676275B (zh) | 2014-05-07 |
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Families Citing this family (1)
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CN102391208A (zh) * | 2011-10-25 | 2012-03-28 | 湖南洞庭药业股份有限公司 | 富马酸喹硫平的新晶形i及其制备方法 |
Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0282236A1 (en) * | 1987-03-10 | 1988-09-14 | Imperial Chemical Industries Plc | Process for the preparation of a thiazepine compound |
CN1537847A (zh) * | 2000-01-25 | 2004-10-20 | ����˹ҩ�﹤�� | 制备奎替阿平的中间体及所述中间体的制备方法 |
CN1777594A (zh) * | 2003-02-22 | 2006-05-24 | 特瓦制药工业有限公司 | 喹迪平及其可药用盐的合成 |
US20060276641A1 (en) * | 2005-04-14 | 2006-12-07 | Kansal Vinod K | Process for preparing quetiapine fumarate |
CN101198599A (zh) * | 2005-04-14 | 2008-06-11 | 特瓦制药工业有限公司 | 制备富马酸喹硫平的方法 |
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- 2008-09-17 CN CN200810222433.6A patent/CN101676275B/zh active Active
Patent Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0282236A1 (en) * | 1987-03-10 | 1988-09-14 | Imperial Chemical Industries Plc | Process for the preparation of a thiazepine compound |
CN1537847A (zh) * | 2000-01-25 | 2004-10-20 | ����˹ҩ�﹤�� | 制备奎替阿平的中间体及所述中间体的制备方法 |
CN1777594A (zh) * | 2003-02-22 | 2006-05-24 | 特瓦制药工业有限公司 | 喹迪平及其可药用盐的合成 |
US20060276641A1 (en) * | 2005-04-14 | 2006-12-07 | Kansal Vinod K | Process for preparing quetiapine fumarate |
CN101198599A (zh) * | 2005-04-14 | 2008-06-11 | 特瓦制药工业有限公司 | 制备富马酸喹硫平的方法 |
Non-Patent Citations (4)
Title |
---|
半富马酸喹硫平的合成研究;梁伟周等;《中国医药工业杂志》;20041231;第35卷(第12期);705-706 * |
喹硫平的合成改进研究;谭云等;《中国新药杂志》;20070615;第16卷(第11期);867-868 * |
梁伟周等.半富马酸喹硫平的合成研究.《中国医药工业杂志》.2004,第35卷(第12期),705-706. |
谭云等.喹硫平的合成改进研究.《中国新药杂志》.2007,第16卷(第11期),867-868. |
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