CN101328169B - 一种乙氧碳酰基-取代噻唑二氢嘧啶 - Google Patents

一种乙氧碳酰基-取代噻唑二氢嘧啶 Download PDF

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Publication number: CN101328169B
Authority: CN; China
Prior art keywords: compound; general formula; composition; salt; medicine
Prior art date: 2007-06-18
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Active

Application number

CN2008101257239A

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English (en)

Chinese (zh)

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CN101328169A (zh

Inventor

S·戈尔德曼

李静

刘遗松

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Guangdong HEC Pharmaceutical

Original Assignee

ZHANG ZHONGNENG

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2007-06-18

Filing date

2008-06-18

Publication date

2011-05-25

2008-06-18 Application filed by ZHANG ZHONGNENG filed Critical ZHANG ZHONGNENG

2008-06-18 Priority to CN2008101257239A priority Critical patent/CN101328169B/zh

2008-12-24 Publication of CN101328169A publication Critical patent/CN101328169A/zh

2011-05-25 Application granted granted Critical

2011-05-25 Publication of CN101328169B publication Critical patent/CN101328169B/zh

Status Active legal-status Critical Current

2028-06-18 Anticipated expiration legal-status Critical

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Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Veterinary Medicine (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
Communicable Diseases (AREA)
Oncology (AREA)
Virology (AREA)
Gastroenterology & Hepatology (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

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WO2010069147A1 (fr) *	2008-12-17	2010-06-24	张中能	Derives de la dihydropyrimidine, leurs compositions et leur utilisation
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KR20210081451A (ko)	2012-08-28	2021-07-01	얀센 사이언시즈 아일랜드 언리미티드 컴퍼니	설파모일-아릴아미드 및 b형 간염 치료제로서의 그 용도
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US9169212B2 (en)	2014-01-16	2015-10-27	Novira Therapeutics, Inc.	Azepane derivatives and methods of treating hepatitis B infections
US10392349B2 (en)	2014-01-16	2019-08-27	Novira Therapeutics, Inc.	Azepane derivatives and methods of treating hepatitis B infections
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DK3102572T3 (en)	2014-02-06	2019-02-04	Janssen Sciences Ireland Uc	SULFAMOYLPYRROLAMIDE DERIVATIVES AND THEIR USE AS MEDICINES TO TREAT HEPATITIS B
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US10875876B2 (en)	2015-07-02	2020-12-29	Janssen Sciences Ireland Uc	Cyclized sulfamoylarylamide derivatives and the use thereof as medicaments for the treatment of hepatitis B
AU2016330964B2 (en)	2015-09-29	2021-04-01	Novira Therapeutics, Inc.	Crystalline forms of a hepatitis B antiviral agent
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CN101328169B (zh)	2011-05-25	一种乙氧碳酰基-取代噻唑二氢嘧啶
CN102066369B (zh)	2013-05-29	一种溴苯基-取代的噻唑二氢嘧啶
CN101328168B (zh)	2011-09-07	一种乙氧碳酰基-取代噻唑二氢嘧啶
CN101328170B (zh)	2011-09-14	一种氟苯基-取代噻唑二氢嘧啶
EP2218720B1 (fr)	2013-01-09	Dérivés de 2-2'-Bis-thiazole en tant que agents antivirales
US6503913B1 (en)	2003-01-07	2-heterocyclically substituted dihydropyrimidines
DE10012549A1 (de)	2001-09-20	Arzneimittel gegen virale Erkrankungen
TW201201804A (en)	2012-01-16	Quinoline compounds and their use for treating viral infection
DE10012824A1 (de)	2001-09-20	Arzneimittel gegen virale Erkrankungen
CZ20021457A3 (cs)	2002-07-17	Tetrahydrothiopyranové sloučeniny
DE10013125A1 (de)	2001-09-20	Arzneimittel gegen virale Erkrankungen
JP2003514896A (ja)	2003-04-22	新規な５−ピリミジンカルボキサミド誘導体及び該誘導体を含む製薬組成物
KR20080058708A (ko)	2008-06-26	Ｚ－ｄｎａ 결합 단백질의 활성을 제어하는 피라졸리딘계 화합물

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