CN108379168A - A kind of cosmetics and preparation method thereof of phytoremediation cuticula - Google Patents
A kind of cosmetics and preparation method thereof of phytoremediation cuticula Download PDFInfo
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
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- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/36—Carboxylic acids; Salts or anhydrides thereof
- A61K8/361—Carboxylic acids having more than seven carbon atoms in an unbroken chain; Salts or anhydrides thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/63—Steroids; Derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/68—Sphingolipids, e.g. ceramides, cerebrosides, gangliosides
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
- A61Q17/005—Antimicrobial preparations
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/10—General cosmetic use
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/20—Chemical, physico-chemical or functional or structural properties of the composition as a whole
- A61K2800/30—Characterized by the absence of a particular group of ingredients
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/41—Particular ingredients further characterized by their size
- A61K2800/412—Microsized, i.e. having sizes between 0.1 and 100 microns
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/59—Mixtures
- A61K2800/592—Mixtures of compounds complementing their respective functions
- A61K2800/5922—At least two compounds being classified in the same subclass of A61K8/18
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Abstract
The present invention provides a kind of cosmetics and preparation method thereof of phytoremediation cuticula, ceramide, aliphatic acid and cholesterine in the cosmetics are combined in certain proportion, synthesize long-chain, and it is folded into meagre layer structure, form cutin, the metabolic turnover for promoting cuticula, improves the safeguard function of cuticula；Purslane extract and Gotu Kola P.E cooperate, and have antiallergic, anti-oxidant, slow down aging, promote the effect of collagen forms, promotes skin quality in skin corium；Peony root extractive and phytosterol cooperate, and have the function of antibacterial, anti-inflammatory, while can improve the permeability of skin.Various components in the cosmetics of phytoremediation cuticula provided by the invention cooperate, and have the metabolism for promoting cuticula, protective barrier is provided for skin；Promote the formation that collagen band is white in skin corium, is improved from deep skin, delay skin aging；Improve the permeability of skin, the effect of promoting the absorbability of skin.
Description
Technical field
The invention belongs to cosmetic fields, and in particular to a kind of cosmetics and preparation method thereof of phytoremediation cuticula.
Background technology
Cosmetics refer to interspersing among any position of human body surface, such as skin with smearing, sprinkling or other similar approach
Skin, hair refer to toenail, lips and teeth etc., to reach cleaning, maintenance, beauty, modification and change appearance, or correct human scent, protect
Hold the chemical industrial product or fine chemical product for the purpose of kilter.Cosmetics are distinguished according to different effects, are had
Can cleaning skin, what is had can obstruct the injury of outer bound pair skin, and what is had can modify appearance etc..And the cosmetics good and the bad is not
Together, the cosmetics much protected can not reach the function of protection, and the safeguard function of cosmetics is mainly realized by cuticula,
The cuticula of skin is the outermost part of epidermis, mainly by 10-20 layers it is flat, do not have nucleolate dead cell to form, when
When these cell detachments, the beneath cell positioned at basal layer, which can be brought to, to be come, and new cuticula is formed.At many people, angle
Matter layer is made of dead flat horn cell, and that maintains it has little significance, in fact on the contrary, skin care
The actually maintenance of Stratum Corneum.And cosmetics in the prior art focus on the supplement of nutritional ingredient, ignore cuticula
It repairs, therefore can not achieve the effect that skin care.
Invention content
For the technical problem more than solving, the present invention, which provides one kind, can effectively repair cuticula, promote cuticula
Metabolism, improves the holding to moisture of cuticula, and the cosmetics with phytoremediation cuticula that is anti-oxidant, promoting infiltration and its
Preparation method.
The object of the present invention is to provide a kind of cosmetics of phytoremediation cuticula.
Another mesh of the present invention is to provide a kind of preparation method of the cosmetics of above-mentioned phytoremediation cuticula.
According to effective group of the cosmetics of the phytoremediation cuticula of the specific embodiment of the invention, including following parts by weight
Point：10-20 parts of purslane extract, 8-12 parts of Gotu Kola P.E, 5-8 parts of peony root extractive, 20-25 parts of phytosterol,
5-8 parts of 8-20 parts of Cer EOS, 15-20 parts of aliphatic acid and cholesterine.
Cuticula is the line of demarcation inside and outside body, has the function of " protecting film ", can not only prevent body interior moisture,
The losses such as nutrient, can also obstruct the stimulants such as viral ultraviolet light or impurity enters in body.It is normally metabolic with skin,
Corneocyte finally can extremely fall off always.But with the continuous growth at age, the metabolic capabilities of human body slow down.Therefore,
Old dead cell also can constantly be accumulated, and pachylosis is caused, lackluster, or even have decortication phenomenon.Plant provided by the invention is repaiied
Ceramide, aliphatic acid and cholesterine in the cosmetics of multiple cuticula is with 18-20:15-20:The ratio of 5-8 is combined, and is closed
At long-chain, and it is folded into meagre layer structure, forms cutin, promote the metabolism of cuticula, improve the protection of cuticula
Function delays the injury of outer bound pair skin, meanwhile, the purslane extract contained in cosmetics provided by the invention and centella
Extract cooperates, and has antiallergic, anti-oxidant, slows down aging, and promotes collagen in skin corium to be formed, promotes skin quality
The effect of；Peony root extractive provided by the invention and phytosterol cooperate, and have natural antibacterial, antiviral, anti-inflammatory
Effect, while have improve skin permeability, keep the moisture of skin surface, promote skin metabolism effect.
The cosmetics of phytoremediation cuticula provided by the invention promote the metabolism of cuticula, excellent protection are provided for skin first
Barrier, then coordinate plant extracts, promote the formation that collagen band is white in skin corium, improved from deep skin, promotes skin
Quality, delay skin aging, and coordinate with antibacterial, antivirus plant extract component, the infiltration of skin can be improved
Property, increase absorption of the skin to nutriment, improves the water lock ability of cuticula, while the present invention avoids chemically synthesized anti-corrosion
The use of agent reduces the burden of skin.
According to the cosmetics of the phytoremediation cuticula of the specific embodiment of the invention, it is preferable that including following parts by weight
Active principle：15 parts of purslane extract, 10 parts of Gotu Kola P.E, 6 parts of peony root extractive, 20 parts of phytosterol, god
Through 6 parts of 20 parts of amide, 20 parts of aliphatic acid and cholesterine.
The cosmetics of phytoremediation cuticula provided by the invention can be used in preparing lotion, day cream, night frost and isolation
In the cosmetics such as frost.
According to the cosmetics of the phytoremediation cuticula of the specific embodiment of the invention, it is preferable that the active principle is also
Including 3-5 parts of N- palmityls hydroxy-proline cetyl.N- palmityl hydroxy-prolines cetyl can be with phytosterol, nerve
Amide, aliphatic acid and cholesterine collective effect, increase the thickness of cuticula, increase the elasticity of skin, inhibit invading for harmful substance
Enter, enhances the adhesion strength between horn cell, improve the sub-health state of skin.
According to the cosmetics of the phytoremediation cuticula of the specific embodiment of the invention, it is preferable that further include auxiliary agent, it is described
The weight ratio of active principle and the auxiliary agent is 81-113:20-30.The component of cosmetics provided by the invention is in addition to including effective
Group exceptionally further includes auxiliary agent, the cosmetics obtained when active principle is combined with auxiliary agent with aforementioned proportion, and fine texture is touched
Feel splendid.
According to the cosmetics of the phytoremediation cuticula of the specific embodiment of the invention, it is preferable that the auxiliary agent include with
The component of lower parts by weight：10-15 parts of 5-7 parts of emulsifier, 5-8 parts of moisturizer and water.
According to the cosmetics of the phytoremediation cuticula of the specific embodiment of the invention, it is preferable that the phytosterol is
Campesterol class.Campesterol class (BRASSICA CAMPESTRIS RAPESEED STEROLS) has human body stronger anti-
Inflammation effect has very high permeability to skin, can promote the metabolism of skin.
According to the preparation method of the cosmetics of the phytoremediation cuticula of the specific embodiment of the invention, including following step
Suddenly：
(1) purslane extract is prepared：Purslane is taken, is crushed, sieving is added in 8-12 times of ethanol solution, in 55-65
DEG C, 45-60min is extracted, filtering takes filtrate, decolourizes, and concentrates, and freeze-drying obtains the purslane extract；
(2) Gotu Kola P.E is prepared：Centella is taken, the ethanol solution of 6-10 times of weight, ultrasonic extraction 20- is added
30min, filtering, obtains filtrate and filter residue, and the ethanol solution of 3-5 times of weight, refluxing extraction 30- are added into the filter residue
60min, filtering obtain filtrate, merge gained filtrate twice, and concentration obtains thick paste, is dissolved in water, obtains into the thick paste
Extracting solution will elute the extracting solution using resin separating column, and eluting solvent is ethanol solution, collect eluent, dense
Contracting, it is dry, obtain the Gotu Kola P.E；
(3) peony root extractive is prepared：Moutan root bark is taken, dry, pulverize, the ethanol solution of 8-12 times of parts by weight is added,
8-10h is extracted, filtering obtains filtrate and filter residue, and the ethanol solution of 5-8 times of parts by weight is added into filter residue, extracts 5-6h, mistake
Filtrate is collected in filter, is merged gained filtrate twice, is concentrated, and freeze-drying obtains the peony root extractive；
(4) Gotu Kola P.E that purslane extract that step (1) obtains, step (2) obtain, step (3) are obtained
Peony root extractive and remaining ingredient mixed, homogeneous obtains the cosmetics of the phytoremediation cuticula.
According to the preparation method of the cosmetics of the phytoremediation cuticula of the specific embodiment of the invention, it is preferable that step
(1) in, the volume fraction of the ethanol solution is 70-80%.
According to the preparation method of the cosmetics of the phytoremediation cuticula of the specific embodiment of the invention, it is preferable that step
(2) in, the detailed process of the elution is that the ethanol solution for being first 15-20% with volume fraction carries out first time elution, then
Using the ethanol solution that volume fraction is 55-60% elute for second, it is the ethyl alcohol of 75-90% finally to use volume fraction
Solution carries out third time elution.The method of the stepwise elution of Gotu Kola P.E provided by the invention, gradually elutes centella
In active ingredient, extraction efficiency is high.
According to the preparation method of the cosmetics of the phytoremediation cuticula of the specific embodiment of the invention, it is preferable that step
(4) in, the pressure of the homogeneous is 45-50MPa.
The pressure homogenization through 45-50MPa in homogenizing process of the cosmetics of the phytoremediation cuticula of the present invention obtains
To cosmetics in average grain diameter for 1 μm hereinafter, and the average diameter of human epidermal micropore at 1.5 μm or so, therefore this hair
The cosmetics that the method for bright offer obtains can be deep into human skin, promote the absorption of active ingredient.
Beneficial effects of the present invention are：
The present invention provides a kind of cosmetics of phytoremediation cuticula, ceramide, aliphatic acid in the cosmetics and
Cholesterine is combined in certain proportion, synthesizes long-chain, and be folded into meagre layer structure, forms cutin, is promoted
The metabolic turnover of cuticula improves the safeguard function of cuticula, delays the injury of outer bound pair skin；Cosmetics provided by the invention
In the purslane extract that contains and Gotu Kola P.E cooperate, there is antiallergic, it is anti-oxidant, slow down aging, promote corium
The effect of collagen is formed in layer, promotion skin quality；Peony root extractive provided by the invention and phytosterol phase interworking
It closes, has the function of natural antibacterial, antiviral, anti-inflammatory, while the permeability of skin can be improved, keep the water of skin surface
Point, promote effect of the metabolism of skin.The cosmetics of phytoremediation cuticula provided by the invention, promote cuticula first
Metabolism, excellent protective barrier is provided for skin, then coordinate plant extracts, promotes the white formation of collagen band in skin corium,
Improved from deep skin, promotes the quality of skin, delay skin aging, and coordinate with antibacterial, antivirus plant
Extract component can improve the permeability of skin, increase absorption of the skin to nutriment, while the present invention is closed without using chemistry
At preservative, reduce the burden of skin.
The present invention provides the preparation method of the cosmetics of above-mentioned phytoremediation cuticula, by prepare purslane extract,
Gotu Kola P.E, peony root extractive improve the extraction efficiency of the active ingredient in these plants, obtain active constituent content
Then each component is carried out homogenization by high plant extracts, the cosmetics permeance property of obtained phytoremediation cuticula
Height is added without chemical preservative, safe and non-toxic.
Specific implementation mode
To make the object, technical solutions and advantages of the present invention clearer, technical scheme of the present invention will be carried out below
Detailed description.Obviously, described embodiments are only a part of the embodiments of the present invention, instead of all the embodiments.Base
Embodiment in the present invention, those of ordinary skill in the art are obtained all without making creative work
Other embodiment belongs to the range that the present invention is protected.
Embodiment 1
The cosmetics of phytoremediation cuticula, including active principle 81g and auxiliary agent 20g, active principle include that purslane carries
Take object 10g, Gotu Kola P.E 8g, peony root extractive 5g, phytosterol 20g, Cer EOS 8g, aliphatic acid 15g and cholesteric
Alcohol 5g；Auxiliary agent includes：Emulsifier 5g, moisturizer 5g and water 10g.
The preparation method of the cosmetics of above-mentioned phytoremediation cuticula, includes the following steps：
(1) purslane extract is prepared：Purslane is taken, is crushed, it is molten that the ethyl alcohol that 8 times of volume fractions are 70% is added in sieving
In liquid, at 55 DEG C, 60min is extracted, filtering takes filtrate, decolourizes, and concentrates, and freeze-drying obtains the purslane extract；
(2) Gotu Kola P.E is prepared：Centella is taken, the ethanol solution that the volume fraction of 6 times of weight is 75% is added, surpasses
Sound extracts 20min, and filtering obtains filtrate and filter residue, and the volume fraction of 3 times and total amount is added into the filter residue as 75% second
Alcoholic solution, refluxing extraction 30min, filtering obtain filtrate, merge gained filtrate twice, and concentration obtains thick paste, to the thick paste
In be dissolved in water, obtain extracting solution, the extracting solution will be eluted using resin separating column, the detailed process of elution is：
First with volume fraction be 15% ethanol solution carries out first time elution, then use volume fraction for 55% ethanol solution into
Second of elution of row, finally uses the ethanol solution that volume fraction is 75% to carry out third time elution, collects eluent, concentrate,
It is dry, obtain the Gotu Kola P.E；
(3) peony root extractive is prepared：Moutan root bark is taken, dry, pulverize, the volume fraction that 8 times of parts by weight are added is
75% ethanol solution extracts 8h, and filtering obtains filtrate and filter residue, and the volume fraction that 5 times of parts by weight are added into filter residue is
75% ethanol solution extracts 5h, and filtrate is collected in filtering, merges gained filtrate twice, concentrates, and freeze-drying obtains described male
Red root extract；
(4) Gotu Kola P.E that purslane extract that step (1) obtains, step (2) obtain, step (3) are obtained
Peony root extractive and remaining ingredient mixed, pressure be 45MPa under carry out homogeneous, obtain the phytoremediation cutin
The cosmetics of layer.
Embodiment 2
The cosmetics of phytoremediation cuticula, including active principle 113g and auxiliary agent 30g, active principle include that purslane carries
Take object 20g, Gotu Kola P.E 12g, peony root extractive 8g, phytosterol 25g, Cer NS 0g, aliphatic acid 20g and courage
Sterol 8g；Auxiliary agent includes：Emulsifier 7g, moisturizer 8g and water 15g.
The preparation method of the cosmetics of above-mentioned phytoremediation cuticula, includes the following steps：
(1) purslane extract is prepared：Purslane is taken, is crushed, it is molten that the ethyl alcohol that 12 times of volume fractions are 80% is added in sieving
In liquid, at 65 DEG C, 45min is extracted, filtering takes filtrate, decolourizes, and concentrates, and freeze-drying obtains the purslane extract；
(2) Gotu Kola P.E is prepared：Centella is taken, the ethanol solution that the volume fraction of 10 times of weight is 75% is added,
Ultrasonic extraction 20min, filtering, obtains filtrate and filter residue, and the second that the volume fraction of 5 times of weight is 75% is added into the filter residue
Alcoholic solution, refluxing extraction 60min, filtering obtain filtrate, merge gained filtrate twice, and concentration obtains thick paste, to the thick paste
In be dissolved in water, obtain extracting solution, the extracting solution will be eluted using resin separating column, the detailed process of elution is：
First with volume fraction be 20% ethanol solution carries out first time elution, then use volume fraction for 60% ethanol solution into
Second of elution of row, finally uses the ethanol solution that volume fraction is 90% to carry out third time elution, collects eluent, concentrate,
It is dry, obtain the Gotu Kola P.E；
(3) peony root extractive is prepared：Moutan root bark is taken, dry, pulverize, the volume fraction that 12 times of parts by weight are added is
75% ethanol solution extracts 12h, and filtering obtains filtrate and filter residue, and the volume fraction that 8 times of parts by weight are added into filter residue is
75% ethanol solution extracts 6h, and filtrate is collected in filtering, merges gained filtrate twice, concentrates, and freeze-drying obtains described male
Red root extract；
(4) Gotu Kola P.E that purslane extract that step (1) obtains, step (2) obtain, step (3) are obtained
Peony root extractive and remaining ingredient mixed, pressure be 50MPa under carry out homogeneous, obtain the phytoremediation cutin
The cosmetics of layer.
Embodiment 3
The cosmetics of phytoremediation cuticula, including active principle 99g and auxiliary agent 24g, active principle include that purslane carries
Take object 15g, Gotu Kola P.E 10g, peony root extractive 6g, phytosterol 20g, Cer NS 0g, aliphatic acid 20g and courage
Sterol 8g；Auxiliary agent includes：Emulsifier 6g, moisturizer 6g and water 12g.
The preparation method of the cosmetics of above-mentioned phytoremediation cuticula, includes the following steps：
(1) purslane extract is prepared：Purslane is taken, is crushed, it is molten that the ethyl alcohol that 10 times of volume fractions are 75% is added in sieving
In liquid, at 60 DEG C, 60min is extracted, filtering takes filtrate, decolourizes, and concentrates, and freeze-drying obtains the purslane extract；
(2) Gotu Kola P.E is prepared：Centella is taken, the ethanol solution that the volume fraction of 10 times of weight is 75% is added,
Ultrasonic extraction 30min, filtering, obtains filtrate and filter residue, and the second that the volume fraction of 5 times of weight is 75% is added into the filter residue
Alcoholic solution, refluxing extraction 60min, filtering obtain filtrate, merge gained filtrate twice, and concentration obtains thick paste, to the thick paste
In be dissolved in water, obtain extracting solution, the extracting solution will be eluted using resin separating column, the detailed process of elution is：
First with volume fraction be 20% ethanol solution carries out first time elution, then use volume fraction for 60% ethanol solution into
Second of elution of row, finally uses the ethanol solution that volume fraction is 90% to carry out third time elution, collects eluent, concentrate,
It is dry, obtain the Gotu Kola P.E；
(3) peony root extractive is prepared：Moutan root bark is taken, dry, pulverize, the volume fraction that 10 times of parts by weight are added is
75% ethanol solution extracts 10h, and filtering obtains filtrate and filter residue, and the volume fraction that 6 times of parts by weight are added into filter residue is
75% ethanol solution extracts 6h, and filtrate is collected in filtering, merges gained filtrate twice, concentrates, and freeze-drying obtains described male
Red root extract；
(4) Gotu Kola P.E that purslane extract that step (1) obtains, step (2) obtain, step (3) are obtained
Peony root extractive and remaining ingredient mixed, pressure be 50MPa under carry out homogeneous, obtain the phytoremediation cutin
The cosmetics of layer.
Embodiment 4
The cosmetics of phytoremediation cuticula, including active principle 102g and auxiliary agent 24g, active principle include that purslane carries
Take object 15g, Gotu Kola P.E 10g, peony root extractive 6g, campesterol class 20g, Cer NS 0g, aliphatic acid 20g, courage
Sterol 8g and N- palmityl hydroxy-proline cetyl 3g；Auxiliary agent includes：Emulsifier 6g, moisturizer 6g and water 12g.
The preparation method of the cosmetics of above-mentioned phytoremediation cuticula, includes the following steps：
(1) purslane extract is prepared：Purslane is taken, is crushed, it is molten that the ethyl alcohol that 10 times of volume fractions are 75% is added in sieving
In liquid, at 60 DEG C, 60min is extracted, filtering takes filtrate, decolourizes, and concentrates, and freeze-drying obtains the purslane extract；
(2) Gotu Kola P.E is prepared：Centella is taken, the ethanol solution that the volume fraction of 10 times of weight is 75% is added,
Ultrasonic extraction 30min, filtering, obtains filtrate and filter residue, and the second that the volume fraction of 5 times of weight is 75% is added into the filter residue
Alcoholic solution, refluxing extraction 60min, filtering obtain filtrate, merge gained filtrate twice, and concentration obtains thick paste, to the thick paste
In be dissolved in water, obtain extracting solution, the extracting solution will be eluted using resin separating column, the detailed process of elution is：
First with volume fraction be 20% ethanol solution carries out first time elution, then use volume fraction for 60% ethanol solution into
Second of elution of row, finally uses the ethanol solution that volume fraction is 90% to carry out third time elution, collects eluent, concentrate,
It is dry, obtain the Gotu Kola P.E；
(3) peony root extractive is prepared：Moutan root bark is taken, dry, pulverize, the volume fraction that 10 times of parts by weight are added is
75% ethanol solution extracts 10h, and filtering obtains filtrate and filter residue, and the volume fraction that 6 times of parts by weight are added into filter residue is
75% ethanol solution extracts 6h, and filtrate is collected in filtering, merges gained filtrate twice, concentrates, and freeze-drying obtains described male
Red root extract；
(4) Gotu Kola P.E that purslane extract that step (1) obtains, step (2) obtain, step (3) are obtained
Peony root extractive and remaining ingredient mixed, pressure be 50MPa under carry out homogeneous, obtain the phytoremediation cutin
The cosmetics of layer.
Embodiment 5
The cosmetics of phytoremediation cuticula, including active principle 104g and auxiliary agent 24g, active principle include that purslane carries
Take object 15g, Gotu Kola P.E 10g, peony root extractive 6g, campesterol class 20g, Cer NS 0g, aliphatic acid 20g, courage
Sterol 8g and N- palmityl hydroxy-proline cetyl 5g；Auxiliary agent includes：Emulsifier 6g, moisturizer 6g and water 12g.
The preparation method of the cosmetics of above-mentioned phytoremediation cuticula, includes the following steps：
(1) purslane extract is prepared：Purslane is taken, is crushed, it is molten that the ethyl alcohol that 10 times of volume fractions are 75% is added in sieving
In liquid, at 60 DEG C, 60min is extracted, filtering takes filtrate, decolourizes, and concentrates, and freeze-drying obtains the purslane extract；
(2) Gotu Kola P.E is prepared：Centella is taken, the ethanol solution that the volume fraction of 10 times of weight is 75% is added,
Ultrasonic extraction 30min, filtering, obtains filtrate and filter residue, and the second that the volume fraction of 5 times of weight is 75% is added into the filter residue
Alcoholic solution, refluxing extraction 60min, filtering obtain filtrate, merge gained filtrate twice, and concentration obtains thick paste, to the thick paste
In be dissolved in water, obtain extracting solution, the extracting solution will be eluted using resin separating column, the detailed process of elution is：
First with volume fraction be 20% ethanol solution carries out first time elution, then use volume fraction for 60% ethanol solution into
Second of elution of row, finally uses the ethanol solution that volume fraction is 90% to carry out third time elution, collects eluent, concentrate,
It is dry, obtain the Gotu Kola P.E；
(3) peony root extractive is prepared：Moutan root bark is taken, dry, pulverize, the volume fraction that 10 times of parts by weight are added is
75% ethanol solution extracts 10h, and filtering obtains filtrate and filter residue, and the volume fraction that 6 times of parts by weight are added into filter residue is
75% ethanol solution extracts 6h, and filtrate is collected in filtering, merges gained filtrate twice, concentrates, and freeze-drying obtains described male
Red root extract；
(4) Gotu Kola P.E that purslane extract that step (1) obtains, step (2) obtain, step (3) are obtained
Peony root extractive and remaining ingredient mixed, pressure be 50MPa under carry out homogeneous, obtain the phytoremediation cutin
The cosmetics of layer.
Test example 1
Choose certain commercially available oxidation resistant face cream of brand moisturizing (control group) and phytoremediation cuticula that embodiment 5 obtains
Cosmetics (test group) carry out moisture content of skin test using moisture of skin tester, the temperature of test is room temperature, relatively wet
Degree is (45 ± 5) %；Every morning and evening use once respectively, and the average applying amount of each skin is 1.5mg/cm2, even
It is continuous to use 10 days, it is once tested within every two days, test is multiple every time, calculates and records average result, the results are shown in Table 1.
1 moisture content of skin test result of table
| Time (day) | Control group water content (%) | Test group water content (%) |
| 0 | 21.31±1.52 | 21.42±1.78 |
| 2 | 24.64±2.36 | 24.53±2.48 |
| 4 | 25.35±3.12 | 27.89±3.25 |
| 6 | 26.58±3.54 | 30.69±3.12 |
| 8 | 26.54±3.16 | 34.13±2.68 |
| 10 | 27.16±3.42 | 37.68±3.24 |
From the results shown in Table 1, the cosmetics of phytoremediation cuticula provided by the invention, being capable of constantly improve skin
The moisture-retaining capacity of skin, and the moisture-retaining capacity of skin will be realized by cuticula, this also illustrates cosmetics provided by the invention
The effect of cuticula can be repaired, reach protection moisturizing.
The above description is merely a specific embodiment, but scope of protection of the present invention is not limited thereto, any
Those familiar with the art in the technical scope disclosed by the present invention, can easily think of the change or the replacement, and should all contain
Lid is within protection scope of the present invention.Therefore, protection scope of the present invention should be based on the protection scope of the described claims.
Claims (10)
1. a kind of cosmetics of phytoremediation cuticula, which is characterized in that include the active principle of following parts by weight：Purslane carries
Take 10-20 parts of object, 8-12 parts of Gotu Kola P.E, 5-8 parts of peony root extractive, 20-25 parts of phytosterol, Cer EOS 8-
5-8 parts of 20 parts, 15-20 parts of aliphatic acid and cholesterine.
2. the cosmetics of phytoremediation cuticula according to claim 1, which is characterized in that including having for following parts by weight
Imitate component：15 parts of purslane extract, 10 parts of Gotu Kola P.E, 6 parts of peony root extractive, 20 parts of phytosterol, neural acyl
6 parts of 20 parts of amine, 20 parts of aliphatic acid and cholesterine.
3. the cosmetics of phytoremediation cuticula according to claim 1, which is characterized in that the active principle further includes
3-5 parts of N- palmityls hydroxy-proline cetyl.
4. the cosmetics of phytoremediation cuticula according to claim 1, which is characterized in that further include auxiliary agent, it is described to have
The weight ratio for imitating component and the auxiliary agent is 81-113:20-30.
5. the cosmetics of phytoremediation cuticula according to claim 4, which is characterized in that the auxiliary agent includes following heavy
Measure the component of part：10-15 parts of 5-7 parts of emulsifier, 5-8 parts of moisturizer and water.
6. according to the cosmetics of any phytoremediation cuticula of claim 1-5, which is characterized in that the phytosterol
For campesterol class.
7. the preparation method of the cosmetics of any phytoremediation cuticula of claim 1-5, which is characterized in that including with
Lower step：
(1) purslane extract is prepared：Purslane is taken, is crushed, sieving is added in 8-12 times of ethanol solution, at 55-65 DEG C, carries
45-60min is taken, filters, takes filtrate, is decolourized, is concentrated, freeze-drying obtains the purslane extract；
(2) Gotu Kola P.E is prepared：Centella is taken, the ethanol solution of 6-10 times of weight, ultrasonic extraction 20-30min, mistake is added
Filter, obtains filtrate and filter residue, and the ethanol solution of 3-5 times of weight is added into the filter residue, and refluxing extraction 30-60min is filtered,
Filtrate is obtained, gained filtrate twice is merged, concentration obtains thick paste, is dissolved in water into the thick paste, obtains extracting solution, utilizes
Resin separating column elutes the extracting solution, and eluting solvent is ethanol solution, collects eluent, concentrates, dry, obtains institute
State Gotu Kola P.E；
(3) peony root extractive is prepared：Moutan root bark is taken, dry, pulverize, the ethanol solution of 8-12 times of parts by weight, extraction is added
8-10h, filtering, obtains filtrate and filter residue, and the ethanol solution of 5-8 times of parts by weight is added into filter residue, extracts 5-6h, filters, and receives
Collect filtrate, merge gained filtrate twice, concentrate, freeze-drying obtains the peony root extractive；
(4) Gotu Kola P.E that purslane extract that step (1) obtains, step (2) obtain, step (3) are obtained male
Red root extract and remaining ingredient are mixed, homogeneous, obtain the cosmetics of the phytoremediation cuticula.
8. the preparation method of the cosmetics of phytoremediation cuticula according to claim 7, which is characterized in that step (1)
In, the volume fraction of the ethanol solution is 70-80%.
9. the preparation method of the cosmetics of phytoremediation cuticula according to claim 7, which is characterized in that step (2)
In, the detailed process of the elution is：The ethanol solution for being first 15-20% with volume fraction carries out first time elution, then makes
The ethanol solution for being 55-60% with volume fraction carries out second and elutes, and finally uses the ethyl alcohol that volume fraction is 75-90% molten
Liquid carries out third time elution.
10. the preparation method of the cosmetics of phytoremediation cuticula according to claim 7, which is characterized in that step (4)
In, the pressure of the homogeneous is 45-50MPa.
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