CN1079649C - Nutrient concurrently used as medicated diet and cosmetics for preventing and curing hypersensitive stain, senility and obesity and its manufacture method - Google Patents

Abstract

The present invention relates to a nutrient concurrently used as a medicated diet and a cosmetic for preventing and treating allergy, stain, senility and obesity, and a preparing method thereof. The nutrient is characterized in that the nutrient is prepared from the compound oil of linoleic acid sources, the compound oil of linolenic acid sources, compound trace elements and compound nucleotide. The nutrient can be used for producing edible cosmetics, nutrients, health-care products, medicines, foods, beverages, flavorings and infant or baby foods, and can be used for preventing and treating skin allergy, such as dermatitis, skin rash, miliaria, alopecia, stain, obesity, other diseases of cardiovascular systems and cerebrovascular systems, etc. The nutrient is capable of improving cell viability and immunity, restoring skin and nerve cell damage, resisting senility and improving vision, intelligence and memory, and is an ideal multifunctional cosmetic which can be used as a medicated diet and can be used internally and externally.

Description

Prevent and treat the medicine food cosmetic dual-purpose nutrient and the manufacture method of irritated color spot senility and obesity

The present invention relates to nutrient and method field of manufacturing.

Disclose the old and feeble secret of delaying skin (hair is the extension of skin organ), the appearance of remaining youthful forever and health-physical fitness, the people all thirsts for through the ages.For example the history of the cosmetics ancient Egyptian that can demand before more than 4000 year does eye shadow with rouge and malachite powder, the Cleopatra Ao Paitela that is called as the most beautiful girl in the world, make the beauty treatment cosmetics with olive oil, China women's cosmetics use Shi Yeke traces back to the period in Spring and Autumn and Warring States's epoch before more than 2000 year, and the European just brings into use cosmetics after 18th century.Cosmetics no longer are woman's patents now, and the man has also begun to pay attention to and add this market.

Only thick 2 millimeter of skin deserve to be called " shallow " really, but the organ of human body maximum and the natural cover for defense are the windows of viscera disease, and the traditional Chinese medical science " is hoped, hears, asks, cut " first place that prestige is come the method for diagnosing a disease and proved its importance.Current people the eager desire of delaying decrepitude of skin, to the strong pursuit of desirable skin beauty health-care product and require the strong desire of the panoramic disease of skin of radical cure and a feast for the eyes cosmetics that arise at the historic moment between the generation phychology not only liking but also be afraid of, what like is that the skin care science is in continuous development, what be afraid of is to mix the genuine with the fictitious, uncertain therapeutic efficacy is cut, even produces various serious toxic and side effects.The problem of people's this ambivalence and cosmetics generation now need be such as multi-disciplinary joint efforts and breakthroughs such as skin biology, biochemistry, nutrition, make further progress and solve, this will promote the production and consumption of cosmetics undoubtedly again, and provide scientific basis for people correctly select beauty and health care nutriment such as cosmetics.Therefore, the skin scientific research is an important frontier branch of science and system engineering, is worth further investigation, and its theory and application prospect are very wide.

Yet just skin science present Research be it seems at present, can say still to rest on the primary stage so far have many eternal unsolved mysteries to remain to be untied, and has many can the wait for the research topic that the mankind benefit to explore.Document, monograph data about aspects such as skin biology is not only few but also disperse both at home and abroad, increases the difficulty of innovation research, also makes lots of manufacturers and consumer face the outstanding achievement worthy of the name and the critical shortage of commodity in this respect.That is to say that skin does not occupy due status on its scientific research history, advocating the modern times of liking to be beautiful, should strengthen and quicken the scientific research and the achievement Application and Development of this respect.

Take a broad view of all kinds of cosmetics on the market, be broadly divided into by its function and adjust skin basic cosmetics that makes it to lubricate and the cosmetics that make the skin beauty.A lot of consumers blindly use cosmetics, ignorance can exempt the basic cosmetics that skin is subjected to environmental stimuli for beauty treatment, as scientific research personnel and manufacturer, should consider the two unification, make the consumer dual benefited, have also expanded self potential market.Owing to thinking natural component by mistake, consumers in general do not have the carcinogenic doubtful point that waits of food additives, so natural product comparatively consumer is accepted, cosmetics such as beauty and skin care hair care are no exception, have only natural component can guarantee that just pure safe viewpoint in fact is wrong although think, for example may contain Toxic matter, raw material quality equally can be different different because of region, season etc., problem such as incompatible with other compositions in operational restriction of production technology and the preparation, but the producer finally still has to yield to consumer's requirement, competitively produces so-called natural cosmetics.; simple natural materials can not satisfy the various main nutritional needs of skin; and some compositions are not clear in the plant extraction liquid; effect between the heterogeneity and interact not necessarily complementaryly, the compound prescription that different plant extraction liquids are formed may produce incompatible, and quality is also more difficult stable; maybe can't guarantee comfortable, non-stimulated, nothing allergy; particularly anaphylaxis is the primary safety problem that cosmetics should be considered, because a lot of natural component itself is exactly an anaphylactogen.A lot of natural prodcuts be difficult to satisfy simultaneously four big characteristics that cosmetics must have be effect, comfortable, non-stimulated, do not have allergy, it is allergic that desirable cosmetics also should have control, as dermatitis and some other common disease of very paying close attention to for the consumer again or functions such as defective such as color spot, acne, also should have the Skin Cell of raising vigor simultaneously, critical functions such as opposing senescence process.In addition, existing cosmetics nearly all are single external applications, and skin is difficult to absorb and utilize big molecular nutrition material, even there is a small amount of absorption also only to act on top layer skin, can't penetrate deep layer, big molecule itself easily causes allergy again, has ignored that for oral administration to decompose big molecule by digestive system be little molecular nutrition skin and human body, and the important channel of eliminating its this skin care of anaphylaxis, cosmetics for external use also might cause potential safety hazard because of eating by mistake to child.Have, fat removing has a strong impact on physical and mental health, also follows superfluous skin and flesh, has a strong impact on skin fitness again.

Purpose of the present invention is exactly that the scientific and technological principle of its foundation is as follows for the deficiency that solves prior art provides a kind of medicine food cosmetic dual-purpose nutrient and manufacture method of preventing and treating irritated color spot senility and obesity:

Essential fatty acid EFA (Essential Fat Acid) comprises linoleic acid family and leukotrienes family, and human body can not synthesize voluntarily, must be unrighted acid by food supply.Because human body can be from the synthetic successively a series of essential fatty acids of linoleic acid plus linolenic acid, so they are only real essential fatty acid, i.e. parent essential fatty acid.Under the situation that no parent linoleic acid plus linolenic acid exists, can not synthesize any essential fatty acid in the body, can only from food, obtain.The 4-5% that EFA only need account for total amount of heat can reach the metabolic process that suitable heat energy physiology tired, guaranteed that skin, retina, brain and nervous system normal configuration and function, normal PFT and all energy rely on.It is all low that EFA lacks the EFA content that causes brain, skin and retina cell's phosphatide to reach wherein, the formation of myelin and the growth of brain are damaged greatly, weight and generation dysnusia as direct reduction brain, particularly pregnant, wet nurse and embryo, infant are damaged outstanding weight, last 3 months of gestation to be born back 18 months be the human brain ramp phase, therefore pregnant, wet nurse EFA nutrition is on the low side and premature labor, the infant of low-birth weight have the bigger harm of brain and nervous system disorders.EFA is the important composition of phosphatide, and phosphatide is again biomembranous Main Ingredients and Appearance, epithelial cell and fibroblast dysmaturity when EFA lacks, and the fatty acid structure of skin tissue cell membrane lipid changes, and permeability increases, and easily by microbial infection, and produces irritated.For example the low milk side of baby children feed linoleic acid is when staphy lococcus infection is popular, easily seriously infected; EFA lacks common, multiple skin disease susceptible diseases such as also can making warts disease, prickly heat, dermatitis and is difficult to healing, and scald waits the skin injury healing time to prolong; EFA deficiency or dysbolism make the synthetic minimizing of prostaglandin, because some metabolites of EFA such as arachidonic acid and two all type acid and gamma-linolenics (linoleic acid metabolism generation) and 20 carbon 5 alkene acids (leukotrienes metabolism generation) all are the predecessors of prostaglandin, one of numerous functions of prostaglandin are the mitogenetic and differentiation of management normal epithelium cell, deficiency can cause the skin defense function undermined, other function is synthetic as regulating blood pressure and cholesterol, inflammation such as control such as allergy take place and promote cell proliferation etc., and are all closely related with skin health; The EFA shortage also can lack zinc when causing prostaglandin to lack, because its assists zinc to absorb, eczema sample pathology such as mouth eczema sample pathology on every side occurs, and cystic fibrosis becomes and courage enucleation patient also can cause because of fat absorption is bad.The minimizing of EFA and prostaglandin, can suppress the phosphorylation of happiness oxygen biology and the metabolic process that all energy rely on, depress the formation of blood red cell membrane oxyhemoglobin is seriously disturbed as normal lung oxygen, oxygenate and cellular respiration in the systemic cell are suppressed, the arterial oxygen pressure drop is low, the energy level of supply reduces, and health condition worsens; The FEA also interior saturated fatty acid of control agent makes it unlikely too much, thereby the death rates such as the heart, cerebrovascular system disease such as atherosclerotic that reduction is caused by too much saturated fatty acid, obesity, fatty liver are high, are called human first killer's serious ciril disease.Because EFA is with respect to the demand of fat and total amount of heat 4-5% (minimum 1%) only, amount not quite but very easily lacks for example meets anoxic, stress situation or generation infectious diseases etc. all significantly increase the consumption of EFA, show symptom rapidly, and above-mentioned many critical functions are arranged, during again because of EFA amount in the body and the increase of other unrighted acids, vitamin E metabolism and consumption in vivo also strengthens, vitamin E can improve linoleic physiological function again, it is very similar when the corresponding pathology that body produces during shortage lacks to EFA, vitamin E also can quicken the healing speed of EFA shortage etc., so in recent years more and more scholars generally acknowledge EFA be vitamin and EFA come vitamin E after claim vitaminF, represent that also EFA is a fatty vitamin.Leukotrienes and effect are worth further pointing out among the EFA: clinical medicine proves, the linoleic acid that people ingest generally is converted into gamma-Linolenic acid in vivo earlier, it is prostaglandin that this reaction needs with being converted into two all type gamma-Linolenic acids again after δ-the 6-desaturase is participated in, and it is higher 170 times than linoleic acid that gamma-Linolenic acid reduces the effect of plasma cholesterol; Numerous disease such as diabetes, senile disease, virus infections and idiosyncrasy disorder etc., the capital is disturbed the function of δ-6-D acid and is hindered γ one linolenic generation, even there is this moment sufficient linoleic acid also can cause the prostaglandin hyposecretion, body's immunity regulating system and metabolism further weaken; Alpha-linolenic acid in human body through desaturation and carbochain prolongation effect, generating DHA is that DHA and eicosapentaenoic acid are metabolism materials such as EPA, DHA and EPA tool strengthen memory and eyesight effect, because they are main components of cephalin and retina phosphatide, can protect the 26S Proteasome Structure and Function of brain and central nervous system cell well, by laudatory title is brain gold, is the effective constituent that mainly contains of expensive deep sea fish oil; Alpha-linolenic acid is also had a reducing blood lipid, antithrombotic and is formed and the control diseases of cardiovascular and cerebrovascular systems, suppresses the cancer cell diffusion and effect such as anticancer.In addition, another key property of EFA can be smeared and be absorbed rapidly exactly and bring into play various effects by skin, does not only have any spread effect, prevents and treats serial disease of skin such as dermatitis again, and, also can only cure and to take effect rapidly and thoroughly healing by EFA because of EFA lacks the disease that causes.

Vitamin C is participated in the formation of collagen, make injured neural rehabilitation, keep skin elasticity and vigor and prevent and treat disease such as neurodermatitis, vitamin C impels the tyrosine oxidation, reducing melanin generates, be beneficial to the removal skin splash, also can reduce cholesterol and triglyceride is prevented and treated artery sclerosis, increase interferon and generate antiviral and anti-infective as staphylococcus aureus etc.Vitamin E can be strengthened also can quickening to remove antigen outside the EFA effect as described above, reduces allergic reaction such as fash, color spot etc., improves whole body to effects such as the resistance, the protection vitamin A that infect are not oxidized.Vitamin A can reduce collagen degraded and crease-resistant, delay or reverse skin senescence, keep epithelial cell integrality and cell membrane stability, opposing is irritated and infect, lack to cause that skin delayed type hypersensitivity, DTH, Keratoderma papule, dry coarse furfur, pigmentation, hair simply come off etc.Cobastab ₅Be the bioactive pantothenic acid form of tool, can reduce the time of wound healing 40%, glabrous skin and hair, be absorbed fast and the skin nutrition hair, regulate and maintenance moisture, strengthen pliability, opposing machinery and chemical damage improve humoral immunity etc. as washing and dressing and scalding, have hair dyed.Cobastab ₁, B ₂And B ₆Have the oiliness that reduces oily hair and skin, prevent and treat seborrhea, oedema and pigmentation improve functions such as infecting resistance.The trace element zinc deficiency makes that collagen is synthetic to produce that obstacle, dermatitis, baby's dermatitis, baldness, cell and humoral immunity descend as the killing tumor cells ability reduces, in the body surplus in the of 100 the enzyme of kind and immunity, energy and nucleic acid metabolism the zinc participation is all arranged or makes constituent.Trace elements of selenium makes the peroxide accelerated decomposition, and vitamin E prevents the generation of unsaturated fat acid peroxide, though the two mechanism of action is different, but the identical production concentration that promptly reduces the generation of body peroxide or generate thus of oxidation resistant biochemical effect, selenium has resistant function to some carcinogenic substance, and this is to very easily directly carcinogenic skin of contact and cosmetics are particularly important.Inosine is uniquely can replace ATP, be atriphos (can not directly enter cell membrane) and CoA be the direct permeate through cell membranes of coacetylase enter human body cell with remove the purine class nucleotides source of cell low-energy state, make the cell that is under the low energy anaerobic condition particularly cosmetics directly the Skin Cell vigor of service return to normal level rapidly; Thymidine is a miazines nucleotides, inosine and thymidine have the various purine that can change into nucleic acid respectively and pyrimidine nucleotide simultaneously and through the synthetic complete nucleic acid of nucleic acid synthesis mechanism to improve cell viability, from solving an anti-ageing difficult problem in essence, and thymidine has replacement VB ₁₂Keep the cell proper splitting with folic acid, assist the synthetic critical functions such as strengthening immunity that reaches of active methyl, these are very important to protection skin and body cell vigor.

The medicine food cosmetic dual-purpose nutrient of the irritated color spot senility and obesity of control provided by the invention is with refining turnip oil, Semen Lepidii Semen Desurainiae oil, corn oil, safflower oil, sunflower seed oil, linseed oil, Cobastab ₁, B ₂, B ₅, B ₆A, C, E, sodium selenite, zinc oxide, inosine, or corresponding inosinicacid and sodium salt and thymidine or corresponding thymidylic acid and sodium salt make, and its raw material materials (deduction water content) are by weight: turnip oil 1-20 part (containing linoleic acid 50%), safflower oil (safflower oil) 1-20 part (containing linoleic acid 70%), corn oil 1-20 part (containing linoleic acid 50%), sunflower seed oil 1-20 part (containing linoleic acid 50%), Semen Lepidii Semen Desurainiae oil 1-20 part (contain leukotrienes 48% and 38% and be alpha-linolenic acid), primrose oil 1-20 part (containing linoleic acid 86%), linseed oil 1-20 part (containing leukotrienes 43%), inosine or inosinicacid or inosinicacid sodium salt 1-3.5 part, thymidine or thymidylic acid or thymidylic acid sodium salt 1-3.2 part, VA 0.001-0.01 part, VC 1-2 part, VE 1-2 part, VB ₁0.1-0.3 part, VB ₂0.1-0.3 part, VB ₅0.1-0.3 part, VB ₆0.1-0.3 part, sodium selenite 0.001-0.01 part, zinc oxide 0.01-0.2 part

The derivative of the identical physiological action of the also available GB2760-1996 approval of the various vitamins in the above-mentioned prescription and selenium, zinc substitutes or share, and consumption is by the conversion of tiring of active principle and physiology.

The foundation of prescription is supplemented as follows:

Be tested and appraised to 1998 from national natural science fund subsidy project in 1988 " research and the utilization of new oilseed plant Orychophragmus violaceus " and confirm that turnip oil is the extremely cheap and outstanding essential fatty acid source that contains linoleic acid 49%; 1985 colleges and universities of State Education Commission fund assistance problem " development and use of Cruciferae oilseed plant genetic resources " put special scientific research fund approval with the doctor of colleges and universities of State Education Commission subject in 1992 and subsidize problem and " use relevant Plant Biotechnology; " and be tested and appraised to 1998 to newfound special oil Study on plants, most important achievement is to broadcast ma wormwood artemisia variety source and oil with being worth.Semen Lepidii Semen Desurainiae oil contains alpha-linolenic acid and reaches 38%, be converted into expensive EPA and DHA in vivo, and self is equally cheap and easy to get with turnip oil, 5 pieces of paper income world authoritative journal SCI are arranged, and scientific research level reaches rank first, is latest scientific research, of fine qualities, nutrition and prevention effect are good, and it contains linoleic acid (18%) and leukotrienes simultaneously, are perfect form essential fatty acid sources.

The medicine food cosmetic dual-purpose nutrient and the manufacture method of preventing and treating irritated color spot senility and obesity are:

1. linoleic acid source compound oil and manufacture method are:

In desinfection chamber, press turnip oil 1-20 part, corn oil 1-20 part, safflower oil 1-20 part, sunflower seed oil 1-20 from, primrose oil 1-20 part appoint get a kind of several or all take and do the linoleic acid source, join in the stainless steel equipment of belt stirrer, stirred 5-10 minute the fully airtight use of mixing with 20-60 rev/min rotating speed.

2. flax acid source compound oil and manufacture method are:

In desinfection chamber, press Semen Lepidii Semen Desurainiae oil 1-20 part, linseed oil 1-20 part is appointed and is got a kind of or take and make flax acid source, is added in the stainless steel equipment of belt stirrer, stirs 5-10 minute with 20-60 rev/min rotating speed, and fully mixing is airtight standby.

3. B B-complex and manufacture method are:

Press VA 0.001-0.01, VC 1-2 part, VE 1-2 part, VB at desinfection chamber ₁0.1-0.3 part, VB ₂0.1-0.3 part, VB ₅0.1-0.3 part, VB ₆0.1-0.3 part take by weighing, in the stainless steel mortar porphyrize 2-4 minute, fully grind well and be paste, airtight preservation is standby.

4. composite trace element and manufacture method are:

Aseptic indoor get sodium selenite 0.001-0.01 part, zinc oxide 0.01-0.2 part are arranged, grind in the body to grind at stainless steel and be the smalls shape in 3-5 minute, airtight preservation is standby.

5. compound nucleotide and manufacture method are:

In desinfection chamber, to appoint by inosine, inosinicacid or Sodium Inosinate 1-3.5 part and to get a kind ofly, thymidine, thymidylic acid or thymidylic acid sodium 1-3.2 part are appointed and got a kind ofly, grind 2-3 minute abundant mixing in the stainless steel mortar, and is airtight standby.

6. prevent and treat the preparation of the medicine food cosmetic dual-purpose nutrient of irritated color spot senility and obesity:

In desinfection chamber, the formula rate weighing is pressed in linoleic acid source and flax acid source compound oil, B B-complex, composite trace element and compound nucleotide, in having the stainless steel equipment of agitator, stirred 5-10 minute with 20-40 rev/min rotating speed, fully mixing product.

Prevent and treat the medicine food cosmetic dual-purpose nutrient product of irritated color spot senility and obesity, be limited to example more than the main nutrient composition that contains in per 100 grams (by the calculating of over dry material) and be:

Linoleic acid source compound oil (turnip oil, corn oil, safflower oil, sunflower seed oil, primrose oil one or several) 38.46 grams, flax acid source compound oil (Semen Lepidii Semen Desurainiae oil, linseed oil or any) 38.46 grams, B B-complex 10.00 grams, composite trace element 0.20 gram, compound nucleotide 12.88 grams.

The present invention prevents and treats the purposes of the medicine food cosmetic dual-purpose nutrient product of irritated color spot senility and obesity and produces all kinds of edible cosmetics and the host as Cosmetic Manufacture except that can be used as, but also production varieties of food items.Baby-children product particularly, beverage, flavouring, health products, the host that these products are produced in medicine and conduct, consumption all can add by GMP (ordinary production needs) standard, as various beverages, sweet food, salty food, soup stock, animal and plant sexual health edible blend oil, fragrant, peppery, numb, hot, salty, sweet, bright, sour, flavouring, skin or hair care cream, skin or hair care liquid, medicine and health products such as glue Liang, tablet, oral liquid and cream, electuary, nutrient solution and cream, electuary etc.

Medicine food cosmetic dual-purpose nutrient and manufacture method that the present invention prevents and treats irritated color spot senility and obesity have following advantage:

1. the present invention is according to traditional Chinese medical science inner disease outer treat, the anti-double total inventive concept that principle and consumption habit are considered as a whole of controlling of holding concurrently, adopting the composite natral composition to keep product is natural product, overcome the thin shortcoming of single natural goods effect single force, various nutritional labelings, content, effect and the relation of influencing each other are clear simultaneously, both can be qualitative, and again can be quantitative, raw material quality is stable, and it is in line with international standards to be beneficial to product; It is not clear to have overcome composite parts in the original plant extracts and content and interaction relationship, is difficult for qualitative and quantitative analysis, significant drawback such as raw material quality and source de-stabilising effect production and steady quality.

2. all the components all meets country edible or food additives GB2760-1996 and FDA (FDA), The World Health Organization (WHO), FAO's internal authority organizational standards such as (FAO) and about the definition of natural component promptly from naturally occurring material or with the synthetic material identical of manual method with natural materials, as the dimension C that takes from plant all is considered as natural materials with artificial synthetic dimension C, this has paved road for product and production and marketing merchant open up wide domestic and international market, has solved the suitability for industrialized production raw material sources that adapt to it and has ensured a difficult problem.

3. the high linoleic acid oil sources is extensive relatively in the two class essential fatty acids, but super quality and competitive price the high linolenic oil sources then relatively difficulty seek, particularly the alpha-linolenic acid source can be converted into expensive EPA and DHA in vivo, the present invention is with linoleic acid and leukotrienes and usefulness, not only transferred the interior normal linoleic acid of body and be converted into linolenic function to save flax acid source, the conversion disorder of also having prevented and treated because of aforementioned various common disease settings causes lacking the serial complication that causes because of leukotrienes, thereby make product efficacy comprehensive, with low cost.

4. the B B-complex of the present invention design is the easiest shortage of human body in the numerous kinds of vitamins, and has complementary advantages, do not have antagonism mutually, makes the product overall efficacy extend greatly and strengthen.This four biostearin is jointly used, anti-oxidation efficacy is a synergism, to preventing and treating multiple pathology of other organs of all kinds of dermatitis and body and courses of infection, anti-multiple allergic reaction, sound damaged skin and nerve cell structure and the function of repairing, raising animal economy immunity etc. are evident in efficacy.

5. the composite trace element of the present invention's design is that the numerous crowds in vast region very easily lack, they not only work in coordination with and strengthen the effect of aforementioned each biostearin, selenium also strengthens immunity and improves its physiology and tire with dimension E, dimension C are collaborative, and participates in or swash the in vivo vigor of hundreds of enzyme; Zinc is prevented and treated dermatitis and very itching of causing thus, baldness, short collagen is synthetic, and the short nucleic acid of collaborative B family vitamin is synthetic to improve cell viability, delaying decrepitude of skin etc.

6. the compound nucleotide of the present invention design, purine and pyrimidine are complete, all are single little molecules, very permeable is crossed skin and is directly absorbed, express life-information through changing the complete human body nucleic acid chains of one-tenth capable of being combined, strengthen cell viability, what at first be benefited is Skin Cell, cell hypoxia be can remove immediately and energy and fatigue state lacked, effectively prevent and treat even reverse skin and body aging, and inosine is cheap and easy to get, and effect is got instant result, and this is not only expensive but also can not be difficult to accomplish by ATP and the CoA that the human skin cell is directly advanced in external application; Though the chest pyrimidine is than the inosine costliness, it also can replace VB except that can directly doing the nucleotides application ₁₂Wait effect with these two kinds of vitamins of folic acid in that aforesaid promotion nucleic acid is synthetic, having overcome folic acid needs the just stable and cosmetics of alkaline environment must acid (PH5.5-6.0) just to meet the shortcoming of skin biochemistry environment, VB ₁₂Though acid stable, molecular weight are too big, skin is difficult for absorbing, and absorbs through alimentary canal, needs the glycoprotein combination with a kind of the crying " internal factor " of stomachus pyloricus mucous membrane secretion, could see through the intestines wall to be absorbed, and some people lacks internal factor and causes VB ₁₂Lack and oral invalid, can only inject and make troubles with painful.

7. cosmetics should be subacidity and will guarantee anti-oxidant anti-corruption, the present invention adopt the dimension C adjustment of acidity and with the dimension A, E is jointly anti-oxidant for dimension, the pure natural component and the effect of product have not only been guaranteed, and having prevented may be to the side effects such as allergy of skin as commonly used 0.01% anticorrisive agent triethanolamine and 2-bromo-2-nitro-1 because of adding conventional anti-oxidant and anticorrisive agent, the easy oxidation of ammediol generates nitrosamine and causes irritated and carcinogenic, they can stop the formation of nitrosamine, VA also can reduce the degraded of collagen enzymatic activity and collagen, can obviously reduce the true property of wrinkle, particularly person in middle and old age intractable wrinkle (50-70 year) in 5 weeks.

8. all the components external application is for oral administration because the present invention fills a prescription all easily absorbs, so the production edible cosmetics becomes a reality, has not only improved security, and can bring into play the function of two different absorption approach simultaneously, receives double effect and instant effect.

9. the present invention's not only effect complementation of all the components of filling a prescription, nonirritant, but also initiative is prevented and treated multiple diseases such as skin that various reasons causes and body aging, allergy, color spot, and shorten treatment time greatly, internal and external application is held concurrently anti-.

10. the present invention does not contain any hormone, does not only have any hormone side effect, and the VB in the prescription ₆, the various metabolic deficiencies that all jointly antiestrogenic and other oral contraceptives caused of VC, VA, nucleotides such as tryptophan metabolism defective and side effect significantly consume as the above-mentioned various vitamins that cause because of the clothes contraceptive and the side effect such as go down of the mental depression, anaemia, the sugared dosis tolerata that cause, this is to the numerous women of child-bearing age, and lactication mother and infant's health is very important.

11.EFA shortage make that phosphatide is synthetic to be reduced, cholesterol metabolic is also with phosphatide contention EFA, VB ₆, hypovitaminosis such as pantothenic acid also causes the fat metabolism bad, selenium, zinc are the components of plurality of enzymes in the energetic supersession, these factors all seriously cause fat disease, fatty liver diseases, this product tackles fat good recipe beyond doubt, prevents and treats serious diseases such as obesity in beauty and skin care, and without any side effects, dietary restriction determined curative effect not, instant effect and stable lasting, but no overweight people's health-care face-beautifying is strengthened physique.

12. it is good effect, allergy comfortable, non-stimulated and that therefore cause that the present invention has four big characteristics of outstanding cosmetics.Allergic contact dermatitis accounts for 80% of cosmetics adverse effect, and easily betides important sight position and more little easy more generations of age such as face, lip, eye, and they just are the high-frequency users of cosmetics, so it is very important to prevent and treat allergy.Formula components of the present invention all is little molecules and is the natural existence of the easy shortage of human body and the nutrient that directly absorbs with molecular state, immune system can not be encroached on processing as the big molecule of allosome with it and be caused that immune response stimulates and allergy as producing, and every kind of composition is all at producing irritated material and approach, comprise cosmetics in addition 20% adverse effect as mainly by hormone, brightening agent such as mercury salt and quinhydrones, pigment and unabsorbable mineral oil, self components such as spices cause allergy, pigmentation, heavy metal poisoning and outside sensitizing agent such as pollen, dust, germs etc. are adsorbed in by cosmetics and cause allergic reaction on the skin and the dermatitis that causes of ultraviolet ray (containing light) and pigmentation etc., and jointly control is irritated, skin diseases such as color spot; They absorb and transform rapidly, and softness is not sticking, and so gloss skin is comfortable; Their absorption rates are high, more than 90%, and instant effect, general one course of treatment of 5-6 day, 3-5 days take effect, and how dermatitis disappearance in 7-10 days, 2-3 week cures, and effect is comprehensively complementary, is that VA, VE surfactant are beneficial to the skin absorption as EFA, so effect is good; Their full nutrition skin, improve cell viability, effectively opposing senescence process and obesity, fat liver and series cause disease, oral administration and externally makes renders a service multiplication, and does not have the dosage restriction, and scientific and technological content is very high, science and technology is theoretical genuine and believable, the compound basis abundance, academia generally acknowledges and domestic and international official quality standands is arranged both at home and abroad, meets the various requirement of desirable cosmetics.

13. the control color spot is the cosmetics a great problems, common color spot (pigment deposition) is broadly divided into because of Pigmented butterfly macules of hormonal such as gestation, oral contraceptives, the present invention can effectively prevent and treat and be useful and harmless to pregnant, female tire, baby as described above, and prevent because of stop with quinhydrones, mercurial tyrosinase activity (copper is prothetic group) and bleaching exert an influence the hair blackness and in toxic and side effect; The acne blackspot can and be prevented and treated by B family vitamin control sebum secretion and the short fat metabolism of EFA; Freckle, chloasma increase melanin because of ultraviolet ray and liver function are bad and form, and the present invention also gives solution, and particularly nucleic acid is strengthened the liver cell vigor, and inducing interferon opposing virus etc. make the initiative prevention effect better, are the action that effects a permanent cure; Senile plaque expelling is that the generation of multiple dermatitis also relates to free radical because of the lipofuscin deposition gradually becomes, and these color spots form roughly as follows:

Free radical causes lipid peroxidation to generate material such as MDA making protein cross form polymer such as lipofuscin (senile plaque expelling), be the essential characteristic of cell senescence, be insoluble in water, be difficult for getting rid of so be piled into spot; Free radical is attacked DNA, and the activation carcinogenic substance suppresses the C-AMP enzyme and makes C-AMP and the change of C-GMP concentration cause cell to lose normal contact inhibition, infinitely divides and induced tumor; Free radical activates collagen and hyaluronidase activity and degrade collagen albumen and hyaluronic acid cause skin senescence, wrinkle, arthritis, cataract and retinal damage etc., ultra-violet radiation causes the reaction of light juxtaposition, be photosensitization source (haptens), the free radical that produces becomes holoantigen to start tardy allergy with protein combination, the short tyrosine series of the oxygen radical that produces oxidation reaction generates melanin and the generation of short lipofuscin and causes their deposition, so free radical is the real murderer of skin senescence.The present invention designs multivitamin associating Green Tea Extract, not only power is powerful, and because of the antioxidation that multiplies each other, reduced consumption, avoid certain vitamin effect of single a large amount of use low and side effect also easily do not arranged comprehensively, can cause endocrine disturbance as crossing multidimensional E, also replaced SOD commonly used, Agifutols etc. reach easy oxidation and loss of activity and expensive antioxidant reductase, guarantee the product curative effect and prolong shelf and operating period, also transfer the Skin Cell internal vitality simultaneously and initiatively resist pigment old and feeble as that quicken metabolism and eliminating deposition, prevent from and alleviate to produce new pigment and deposition etc. with nucleic acid.

Embodiment:

1. get 20 parts of linoleic acid source compound oils, 20 parts of flax acid source compound oils, 3 parts of B B-complexes, 0.1 part of composite trace element, 6 parts of compound nucleotides, in the stainless steel agitator, fully mix thoroughly, be used to produce medicine for oral administration, as capsule and pill (every 0.5-2 gram), oral liquid or nutrient solution (5ml-10ml/ bottle), add an amount of cyclodextrin curing and be pressed into tablet (0.5-2 gram/grain), or make health food, beverage additive, enriched nutritive is worth, consumption needs by ordinary production, no dosage restriction prevents and treats diseases such as dermatitis, color spot, obesity.

2. get 15 parts of linoleic acid source compound oils, 15 parts of flax acid source compound oils, 4 parts of B B-complexes, 0.2 part of composite trace element, 3 parts of compound nucleotides, in the stainless steel agitator, fully mix thoroughly, be used for the production external application and smear medicine and edibility cosmetics treatment the dermatitis particularly scorching and all kinds of expansion skin hair care dews of baby's sekunda, liquid, adding an amount of Powdered sucrose ester solidifies or semi-solid preparation, produce all kinds of paste cosmetics, as face cream, face cream, lipstick, lipstick, lip fat, the cream of haircuting, suntan lotion, frost, toothpaste etc.Sucrose fat is nontoxic, and is tasteless, non-stimulated, edible, thus do not influence security and edibility, and sucrose ester tool hydrophilic and oleophilic bidirectional characteristic, with VB ₆Jointly control skin oiliness in appropriate scope, prevent and treat dry skin or seborrhea, improve skin appearance.

3. get 10 parts of linoleic acid source compound oils, 10 parts of flax acid source compound oils, fully miscible with the low EFA edible oil (comprising animal oil) of 80% vegetable seed wet goods, be mixed with edible blend oil, can significantly improve its nutrition, health care, physiology and tire etc. edible and economic worth and promote fat metabolism, control fatty liver diseases.Edible oil market is extremely wide, and market prospects are infinitely bright.

4. get 5 parts of linoleic acid source compound oils, 5 parts of flax acid source compound oils, 2 parts of B B-complexes, 0.02 part of composite trace element, 6 parts of compound nucleotides (inosine is changed to inosinicacid or guanylic acid to increase aquatic foods), in the stainless steel agitator, fully mix thoroughly, produce the high-grade nutrient flavouring or as additive of flavourings as mixing or share with salt, monosodium glutamate, various perfume (or spice), suffering, fiber crops, the former material list of peppery, bright seasoning, produce all kinds of high-grade nutrients, increase bright flavor enhancement.

Claims (3)

1. a medicine of preventing and treating irritated color spot senility and obesity is eaten cosmetic dual-purpose nutrient, is grouped into by following one-tenth:

Linoleic acid source compound oil 1-20 part

Flax acid source compound oil 1-20 part

B B-complex 2.4-5.2 part

Composite trace element 0.011-0.21 part

Compound nucleotide 2-6.7 part

Wherein, the linoleic acid compound oil is made up of turnip oil, corn oil, safflower oil, sunflower oil, primrose oil, and flax acid source compound oil is made up of Semen Lepidii Semen Desurainiae oil, linseed oil, and B B-complex is by VA, VC, VE, VB ₁, VB ₂, VB ₅, VB ₆Form, composite trace element is made up of sodium selenite, zinc oxide, compound nucleotide is made up of inosine, inosinicacid, inosinicacid sodium salt, thymidine, thymidylic acid, thymidylic acid sodium salt, or the derivative that uses the identical physiological action of tool of GB2760-1996 approval substitutes said vitamin and trace element or share, and consumption is by the conversion of tiring of active principle and physiology.

2. prevent and treat the manufacture method foot of the medicine food cosmetic dual-purpose nutrient of irritated color spot senility and obesity:

(1) preparation of linoleic acid source compound oil:

In desinfection chamber, press turnip oil 1-20 part, corn oil 1-20 part, safflower oil 1-20 part, sunflower seed oil 1-20 part, primrose oil 1-20 part appoint get a kind of several or all take and do the linoleic acid source, join in the stainless steel equipment of belt stirrer, stirred 5-10 minute the fully airtight use of mixing with 20-60 rev/min rotating speed;

(2) preparation of flax acid source compound oil:

In desinfection chamber, press Semen Lepidii Semen Desurainiae oil 1-20 part, linseed oil 1-20 part is appointed and is got a kind of or take and make flax acid source, is added in the stainless steel equipment of belt stirrer, stirs 5-10 minute with 20-60 rev/min rotating speed, and fully mixing is airtight standby;

(3) preparation of B B-complex:

Press VA 0.001-0.01, VC 1-2 part, VE 1-2 part, VB at desinfection chamber ₁0.1-0.3 part, VB ₂0.1-0.3 part, VB ₅0.1-0.3 part, VB ₆0.1-0.3 part take by weighing, in the stainless steel mortar porphyrize 2-4 minute, fully grind well and be paste, airtight preservation is standby;

(4) preparation of composite trace element:

Aseptic indoor get sodium selenite 0.001-0.01 part, zinc oxide 0.01-0.2 part are arranged, grind in the body to grind at stainless steel and be the smalls shape in 3-5 minute, airtight preservation is standby;

(5) preparation of compound nucleotide:

In desinfection chamber, to appoint by inosine, inosinicacid or Sodium Inosinate 1-3.5 part and to get a kind ofly, thymidine, thymidylic acid or thymidylic acid sodium 1-3.2 part are appointed and got a kind ofly, grind 2-3 minute abundant mixing in the stainless steel mortar, and is airtight standby;

(6) preparation of the medicine food cosmetic dual-purpose nutrient of the irritated color spot senility and obesity of control:

In desinfection chamber, the formula rate weighing is pressed in linoleic acid source and flax acid source compound oil, B B-complex, composite trace element and compound nucleotide, in having the stainless steel equipment of agitator, stirred 5-10 minute with 20-40 rev/min rotating speed, fully mixing product.

3. prevent and treat the purposes of the medicine food cosmetic dual-purpose nutrient of irritated color spot senility and obesity, it is characterized in that being used for: produce edible cosmetics, host as Cosmetic Manufacture, as producing food particularly baby-children product, beverage, flavouring, health products, medicine and host, consumption needs to use by ordinary production, produce sweet, salty food and beverage, soup stock, of animal or plant nature edible health ready-mixed oil, fragrant, hot, numb, peppery, bright, salty flavouring, skin or hair care cream, liquid, dew, toothpaste, capsule, tablet, electuary, oral liquid, cream, nutrient solution, cream.