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CN107898832A - A kind of canarium pimela rusting vulnerary and preparation method thereof - Google Patents

A kind of canarium pimela rusting vulnerary and preparation method thereof Download PDF

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Publication number
CN107898832A
CN107898832A CN201711258895.9A CN201711258895A CN107898832A CN 107898832 A CN107898832 A CN 107898832A CN 201711258895 A CN201711258895 A CN 201711258895A CN 107898832 A CN107898832 A CN 107898832A
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parts
oil
canarium pimela
extracting solution
vulnerary
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陈志友
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DAXIN COUNTY SCIENCE AND TECHNOLOGY INFORMATION INSTITUTE
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    • A—HUMAN NECESSITIES
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A—HUMAN NECESSITIES
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    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
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    • A61K36/185—Magnoliopsida (dicotyledons)
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    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
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    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/61—Myrtaceae (Myrtle family), e.g. teatree or eucalyptus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/70—Polygonaceae (Buckwheat family), e.g. spineflower or dock
    • A61K36/704—Polygonum, e.g. knotweed
    • A—HUMAN NECESSITIES
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30—Extraction of the material
    • A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation or decoction
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    • A61K2236/333—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using mixed solvents, e.g. 70% EtOH
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    • A61K2236/39—Complex extraction schemes, e.g. fractionation or repeated extraction steps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/50—Methods involving additional extraction steps
    • A61K2236/51—Concentration or drying of the extract, e.g. Lyophilisation, freeze-drying or spray-drying

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Abstract

The invention discloses a kind of canarium pimela rusting vulnerary and preparation method thereof, it is made of the raw material of following parts by weight：20 ~ 30 parts of 8 ~ 15 parts of canarium pimela oil, 3 ~ 8 parts of Baeckea frutescens oil, 8 ~ 15 parts of eucalyptus oil, 20 ~ 30 parts of giant knotweed extracting solution, 20 ~ 30 parts of Flos Lonicerae extractive solution and sowthistle tasselflower herb extracting solution.Preparation method includes：（1）The preparation of extracting solution：Giant knotweed, honeysuckle and sowthistle tasselflower herb are taken, adds medicinal material 8 ~ 12 times of water of weight, decocting 3 times, recycles filtrate, heating concentration, obtains medicinal extract；Ethanol is added in medicinal extract, heating and refluxing extraction three times, recycles merging filtrate, concentration, obtains relative density at 20 DEG C and obtain medicinal extract for 1.12 ~ 1.14, to obtain the final product；（2）Canarium pimela oil, Baeckea frutescens oil and eucalyptus oil are added in extracting solution, is thoroughly mixed, mixture of viscous form is made, be sealed, up to canarium pimela rusting vulnerary.Canarium pimela rusting vulnerary of the present invention relieves pain, is antipruritic, anti-infective, work rapid, preventing from scar.

Description

A kind of canarium pimela rusting vulnerary and preparation method thereof
Technical field
The invention belongs to the field of Chinese medicines, and in particular to a kind of canarium pimela rusting vulnerary and preparation method thereof.
Background technology
Burn refers generally to heating power, including hydrothermal solution（Water, soup, oil etc.）, steam, high-temperature gas, flame, red-hot metal liquid or Solid（Such as molten steel, steel ingot）Deng caused histologic lesion, refer mainly to skin and/or mucous membrane, severe patient can also injure it is subcutaneous or/ And sub-mucosal tissues, such as muscle, bone, joint even internal organ.Scald is as the tissue damage caused by hydrothermal solution, steam etc., is heat One kind of power burn.
And the medicine currently used for burn is very much, common are：Chinese medicine class：Garden burnet, bletilla, giant knotweed, caulis lonicerae, the coptis, Borneol；Long river allusion ~ antimicrobial spray：Smilax, rheum officinale, Cortex Phellodendri, honeysuckle, Fructus Forsythiae, safflower, Asian puccoon, frankincense, myrrh, Angelica sinensis, Radix astragali, the root of Dahurain angelica, earthworm, borneol.Major function：Purging fire and cooling blood, swelling and pain relieving.Be mainly used for burning, scald, can on the surface of a wound shape Into protective film, surface of a wound moisture evaporation is reduced, prevents from infecting, reduce pain.After the application of large area burn, shock hair can be mitigated It is raw.It is more reliable to burn curative effect below small areas I degree.Solar dermatitis also can use.Western medicine：Sulfadiazine Silver Cream etc..But By long-time service for many years, as daily conventional treatment drug, but there is also following shortcoming：（1）Blistering is treated after scald Effect is poor；（2）Easily infection；（3）Antalgesic-antipruritic is ineffective；（4）Easily stay scar.
The content of the invention
In view of the deficiencies of the prior art, the present invention provides it is a kind of can relieve pain, antipruritic, anti-infective, preventing from scar canarium pimela Rusting vulnerary and preparation method thereof.
The technical proposal of the invention is realized in this way：
A kind of canarium pimela rusting vulnerary, is made of the raw material of following parts by weight：8 ~ 15 parts of canarium pimela oil, 3 ~ 8 parts of Baeckea frutescens oil, eucalyptus oil 8 ~ 20 ~ 30 parts of 15 parts, 20 ~ 30 parts of giant knotweed extracting solution, 20 ~ 30 parts of Flos Lonicerae extractive solution and sowthistle tasselflower herb extracting solution.
Further, the canarium pimela rusting vulnerary, is made of the raw material of following parts by weight：Canarium pimela oil 10 parts, Baeckea frutescens oil 5 Part, 10 parts of eucalyptus oil, 25 parts of giant knotweed extracting solution, 25 parts of Flos Lonicerae extractive solution and 25 parts of sowthistle tasselflower herb extracting solution.
The preparation method of the canarium pimela rusting vulnerary, includes the following steps：
（1）The preparation of extracting solution：Giant knotweed, honeysuckle and sowthistle tasselflower herb are taken by above-mentioned parts by weight, is put into crock, adds medicinal material weight 8 ~ 12 times of water are measured, decocting 3 times, 1 ~ 1.5h, recycles filtrate, heating concentration filtrate, it is 1.018 to obtain relative density at 20 DEG C every time ~ 1.110 medicinal extract；Add the ethanol that volume fraction is 85 ~ 95% in medicinal extract, heating and refluxing extraction, it is heated to reflux 2 for the first time ~ 3h, is heated to reflux 1.5h for the second time, is heated to reflux 1h for the third time, recycles merging filtrate, concentrates filtrate, obtains relatively close at 20 DEG C Spend and obtain medicinal extract for 1.12 ~ 1.14, up to extracting solution.
（2）Canarium pimela oil, Baeckea frutescens oil and the eucalyptus oil of above-mentioned parts by weight are added in extracting solution, is thoroughly mixed, makes Into mixture of viscous form, it is sealed, up to canarium pimela rusting vulnerary.
Chinese medicine is good compared with doctor trained in Western medicine to the therapeutic effect of burn, this is because：1. dressing is simple, pain is few.Western medicine is mostly oil Property paste, using ointment medicine, it is necessary to first scrape off/wash away residual ointment during dressing, could again add medicine to, otherwise remains medicine Thing can influence drug effect, or even the arch-criminal as the inflammation for causing wound.2. beneficial to the change of the observation surface of a wound, Chinese medicine is mostly Medicine film water-based, that aqueous pharmaceutical is formed in the surface of a wound, without thickness, and that ointment then to be applied is thicker, can disturb the observation surface of a wound.For Child scalds or human face scalds patient, and aqueous pharmaceutical is even more preferable selection.
It is in addition, as follows for burn, differentiation of tcm viewpoint：
1. thermal burn battalion defends card：Mild burn, no constitutional symptom, is controlled without interior.
2. fiery poison hinders Tianjin card：Syndrome：High fever is irritated, dry happiness drink, and constipation urine is red；Deep red tongue and do, yellow tongue fur or yellow rough, or Tongue light is counted accurately without tongue, full and rapid pulse or string.Therapy：It is clearing heat and detoxicating, supplementing qi and nourishing yin.
3. the impairment of yin sun exhaustion of vital energy at the critical stage of an illness：Syndrome：God is tired sleeping, and pale complexion, tidal air is micro-, apathy, drowsiness, and spontaneous perspiration limb is cold, Body temperature does not rise anti-low, oliguria；Whole body or local edema, the big quantity of fluid exudation of the surface of a wound；The dark tongue of pale tongue is greyish black, or the tender no tongue of pale tongue, Feeble and impalpable pulse is empty powerless etc. greatly.Therapy：Recuperating depleted yang, QI invigorating shield are cloudy.
4. the flourishing card of fiery poison：Syndrome：High fever does not move back, dry mouth and lips, constipation, scanty drak urine；Tongue is red and dry, and yellow tongue fur is done Or yellow greasy, full and rapid pulse.Therapy：It is clearing heat and detoxicating.
5. fiery poison inward invasion syndrome：Syndrome：High fever does not move back, dry mouth and lips, restlessness, constipation, scanty drak urine；Deep red tongue And do, yellow tongue fur or yellow rough or parch play thorn, wiry and frequent pulse etc.；If fiery poison telepathy, it is seen that have the fidgets, coma and delirium；Fiery poison passes lung, It can be seen that rough breath, nasal ala flap, gurgling weith sputum of coughing, blood-stained sputum；Fiery poison passes liver, it is seen that jaundice, double anoopsias, spasm twitch； If fiery poison passes spleen, it is seen that abdominal distension is just tied, and loose stool sticks smelly, nausea and vomiting, do not feel like eating, or is had spitting blood, had blood in stool；Fiery poison passes kidney, can See edema, hematuria or renal shutdown medicine | education network arranges.Therapy：Clearing Ying heat and cooling blood detoxifies.
6. syndrome of deficiency of both qi and blood：Syndrome：End-stage disease, fiery poison are gradually moved back, and low-heat or are not generated heat, tired spirit, the lazy speech of shortness of breath, shape Body is become thin, lusterless complexion, loss of appetite, spontaneous perspiration, night sweat；Wound granulation color is light, and healing is slow；Pale tongue, tongue is thin white or thin Huang, arteries and veins It is thin and delicate.Therapy：Benefiting qi and nourishing blood, and clear residual poison.
7. insufficiency of the spleen impairment of yin card：Syndrome：End-stage disease, fiery poison have been moved back, weakness of the spleen and the stomach, yin jin consume；Sallow complexion, indigestion and loss of appetite food It is few, abdominal distension loose stool, the few Tianjin of dry, or erosion of mucous membrane of the oral cavity and the tongue；Tongue is dark red and dry, tongue stripping or smooth no tongue, thready rapid pulse.Therapy：Tonifying Qi Invigorating the spleen, beneficial stomach yin-nourishing.
Canarium pimela rusting vulnerary of the present invention is controlled viewpoint by differential diagnosis in tcm opinion and is developed, and is below the pharmacological property of each component Analysis：
Canarium pimela oil, for the oil formed using canarium pimela fruit cold press, the oil also squeezed including black canarytree seed.It is natural that canarium pimela oil remains canarium pimela Nutritional ingredient, there is important medical value.Burseraceae olive platymiscium canarium pimela（Canarium pimela Koenig）Alias：Wood Prestige, Hei Lan, black olive.Canarium pimela bark is used for hematemesis with internal injury《Osmanthus medicine is compiled》.Root (black canarytree root)：It is sour, puckery, put down.Hemostasis, resolving sputum, Li Shui, subduing inflammation.For hematemesis with internal injury, cough is numb in every limb, has a stomachache, scald, rheumatalgia, pain in waist and lower extremities.Leaf (black canarytree leaf)： It is puckery, temperature.Hemostasis.For uterine bleeding.Fruit (black canarytree seed)：It is sweet, it is light.Moistening lung, lower gas, enriches blood.Inventor is by grinding canarium pimela oil Study carefully discovery, it maintains most medicinal effects of canarium pimela, especially has particularly pertinent work to scalding, burning etc. With.
Baeckea frutescens oil, is Myrtaceae baeckea frutescen platymiscium baeckea frutescenBaeckea frutescensL. the branches and leaves with flowers and fruits pass through The volatile oil that steam distillation obtains, its main component have：Firpene, 1,8 ~ Cineole, linalool, carypohyllene, humulene etc..Quilt Research thinks that 1,8 ~ Cineole and firpene have eliminating fish parasites tricyclic worm, Dactylogyrus cause to get killed effect；Also research is thought：α ~ pinane Alkene has 7 kinds of Main Stored Grain Insects such as sitophilus zea-mais, confused flour beetle, lesser grain borer, red flour beetle, saw-toothed grain beetle when concentration is higher than 50ppm Very strong smoked kill effect；Linalool is using pest repellant for a long time.Baeckea frutescen nature and flavor：Hardship, trembles with fear, nontoxic；Major function：Stagnation resolvation stops Bitterly, heat-clearing unit of weight measurement, about six liang poison, inducing diuresis for treating strangurtia, desinsection are antipruritic；Cure mainly traumatic injury, tripe hardens, heat is rushed down, heat gonorrhea, difficult urination, pruritus vulvae, foot Gas, eczema, pruitus, mange, scald, worm snake bite；Jiangxi《Herbal medicine handbook》Middle record：Fresh baeckea frutescen is appropriate.Mash External application can control centipede, scorpion, wasp sting.
Eucalyptus oil, also known as cajuputole, cineole, are a kind of colourless oil liquids.With steam distillation from blue gum, eucalyptus Essential oil is extracted in the leaf of Ye Shu, cinnamomum camphora tree and camphor tree etc., branch, processing is re-refined and is made.Main composition：1,8 ~ Cineole（80% with On）, amphene, phellandrene, terpinol, geranyl alcohol, isopentyl aldehyde, citronellal and piperitone etc..With bactericidal effect, greatly Amount is used for pharmaceutical products, is also used in cough drop, chewing gum, gargle, toothpaste and air sanitizer etc..
Giant knotweed（Reynoutria japonica Houtt.）, it is polygonaceae plant giant knotweedPolygonumcuspidatum Sielb.etZucc. dry rhizome and root.【Nature and flavor】Slight bitter, is slightly cold.【Channel tropism】Return liver, courage, lung channel.【Major function】Profit Wet removing jaundice, clearing heat and detoxicating, removing blood stasis and analgesics is relieving cough and reducing sputum.For jaundice with damp-heat pathogen, stranguria with turbid discharge, under band, arthralgia pain due to rheumatism, carbuncle sore tumefacting virus, water Burning hot wound, Amenorrhea, lame lump in the abdomen, traumatic injury, cough with lung heat.
Honeysuckle（Lonicera japonicaThunb.）This product is caprifoliaceae plant honeysuckle, lonicera hypoglauca miq, Honeysuckle flower （Hair calyx honeysuckle or the dry flower of hair style honeysuckle or with the flower just opened.The flowers are in blossom puts preceding harvesting for early summer, dry.【Nature and flavor】It is sweet, It is cold.【Channel tropism】Return lung, the heart, stomach.It is clearing heat and detoxicating, wind-heat dissipating.【Major function】For carbuncle swells furunculosis, larynx numbness, erysipelas, heat toxin Bloody flux, anemopyretic cold, warm disease heating.
Sowthistle tasselflower herb（Emilia sonchifolia (L.)DC.）, for the herb or whole herb with root of feverfew tassel flower. Whole year can adopt, and using fresh herb or dry.【Nature and flavor】Hardship, it is cool.①《The south of the Five Ridges is gathered medicinal herbs record》：" it is sweet in flavor, it is mild-natured."②《Nanning City's medicine will》：" Hardship, it is cool."③《Guangdong Chinese medicine》Ⅱ：" it is cool in nature, it is lightly seasoned, it is nontoxic."【Major function】Heat-clearing, Li Shui, cool blood, removing toxic substances.Control dysentery, Diarrhea, has blood in stool, oedema, acute appendicitis, engages ear, mesh also, tonsillitis, furunculosis, pyogenic infections.
Beneficial effects of the present invention are：
（1）Traditional Chinese medicine for outer use of the present invention by canarium pimela oil, Baeckea frutescens oil, eucalyptus oil, giant knotweed extracting solution, Flos Lonicerae extractive solution and Sowthistle tasselflower herb extracting solution is refined according to scientific compatibility to be formed.Wherein canarium pimela oil not only has the work(of hemostasis, stagnation resolvation, micro- also containing what is enriched The nutrient such as secondary element and mineral matter, controls benefit for burn affected part and combines, and to quick healing of wound, mitigating patient pain has greatly Benefit.In addition Baeckea frutescens oil blood-activating analgetic, heat-clearing unit of weight measurement, about six liang poison, inducing diuresis for treating strangurtia, desinsection are antipruritic, eucalyptus oil sterilizing and itch-relieving, both combinations pair Quick anti-inflammatory, reducing infection is of great benefit to.Giant knotweed stops blooding rapidly；Honeysuckle is clearing heat and detoxicating；Sowthistle tasselflower herb removing toxic substances cool blood.More than it is all into Distribution conjunction brings out the best in each other, and can play the effect of stopping blooding promoting blood circulation, swelling and pain relieving, symplectic bone myogenic, preventing from scar.
（2）Canarium pimela rusting vulnerary of the present invention relieves pain, antipruritic, anti-infective, preventing from scar, compared with traditional Chinese medicine, medicine Effect is rapid, and after first time is by burn or scald, which is uniformly applied to patient skin wound, not blistering, does not infect, Persistently use 3 ~ 7 days, automatic swelling and pain relieving, fully recovers after 10 days.
Embodiment
A kind of canarium pimela rusting vulnerary 1 of embodiment 1
（1）20 parts of giant knotweeds, 20 portions of honeysuckles and 20 parts of sowthistle tasselflower herbs are taken, are put into crock, add medicinal material 8 ~ 12 times of water of weight, decocting 3 times, 1 ~ 1.5h, recycles filtrate, heating concentration filtrate, obtains the medicinal extract that relative density at 20 DEG C is 1.018 ~ 1.110 every time；Leaching The ethanol that volume fraction is 85 ~ 95% is added in cream, heating and refluxing extraction, is heated to reflux 2 ~ 3h, is heated to reflux for the second time for the first time 1.5h, is heated to reflux 1h for the third time, recycles merging filtrate, concentrates filtrate, and relative density must soak for 1.12 ~ 1.14 when obtaining 20 DEG C Cream, up to extracting solution.
（2）8 parts of canarium pimela oil, 3 parts of Baeckea frutescens oils and 8 parts of eucalyptus oils are added in extracting solution, is thoroughly mixed, is made sticky Shape mixture, is sealed, up to canarium pimela rusting vulnerary.
A kind of canarium pimela rusting vulnerary 2 of embodiment 2
（1）25 parts of giant knotweeds, 25 portions of honeysuckles and 25 parts of sowthistle tasselflower herbs are taken, are put into crock, add medicinal material 8 times of water of weight, decocting 3 Secondary, each 1h, recycles filtrate, heating concentration filtrate, obtains to the medicinal extract that relative density at 20 DEG C is 1.018 ~ 1.110；Medicinal extract Middle to add the ethanol that volume fraction is 95%, heating and refluxing extraction, is heated to reflux 2h for the first time, is heated to reflux 1.5h for the second time, the Be heated to reflux 1h three times, recycle merging filtrate, concentrate filtrate, obtain relative density at 20 DEG C and obtain medicinal extract for 1.12 ~ 1.14, to obtain the final product Extracting solution.
（2）10 parts of canarium pimela oil, 5 parts of Baeckea frutescens oils and 10 parts of eucalyptus oils are added in extracting solution, is thoroughly mixed, is made viscous Thick shape mixture, is sealed, up to canarium pimela rusting vulnerary.
A kind of canarium pimela rusting vulnerary 3 of embodiment 3
（1）30 parts of giant knotweeds, 30 portions of honeysuckles and 30 parts of sowthistle tasselflower herbs are taken, are put into crock, add medicinal material 12 times of water of weight, decocting 3 Secondary, each 1.5h, recycles filtrate, heating concentration filtrate, obtains the medicinal extract that relative density at 20 DEG C is 1.018 ~ 1.110；Medicinal extract Middle to add the ethanol that volume fraction is 85%, heating and refluxing extraction, is heated to reflux 3h for the first time, is heated to reflux 1.5h for the second time, the Be heated to reflux 1h three times, recycle merging filtrate, concentrate filtrate, obtain relative density at 20 DEG C and obtain medicinal extract for 1.12 ~ 1.14, to obtain the final product Extracting solution.
（2）15 parts of canarium pimela oil, 8 parts of Baeckea frutescens oils and 15 parts of eucalyptus oils are added in extracting solution, is thoroughly mixed, is made viscous Thick shape mixture, is sealed, up to canarium pimela rusting vulnerary.
A kind of canarium pimela rusting vulnerary 4 of embodiment 4
（1）22 parts of giant knotweeds, 28 portions of honeysuckles and 26 parts of sowthistle tasselflower herbs are taken, are put into crock, add medicinal material 10 times of water of weight, decocting 3 Secondary, each 1.h, recycles filtrate, heating concentration filtrate, obtains the medicinal extract that relative density at 20 DEG C is 1.018 ~ 1.110；In medicinal extract The ethanol that volume fraction is 90% is added, heating and refluxing extraction, is heated to reflux 2.5h for the first time, is heated to reflux 1.5h for the second time, the Be heated to reflux 1h three times, recycle merging filtrate, concentrate filtrate, obtain relative density at 20 DEG C and obtain medicinal extract for 1.12 ~ 1.14, to obtain the final product Extracting solution.
（2）9 parts of canarium pimela oil, 6 parts of Baeckea frutescens oils and 12 parts of eucalyptus oils are added in extracting solution, is thoroughly mixed, is made viscous Thick shape mixture, is sealed, up to canarium pimela rusting vulnerary.
A kind of canarium pimela rusting vulnerary 5 of embodiment 5
（1）23 parts of giant knotweeds, 24 portions of honeysuckles and 28 parts of sowthistle tasselflower herbs are taken, are put into crock, add medicinal material 9 times of water of weight, decocting 3 Secondary, each 1.2h, recycles filtrate, heating concentration filtrate, obtains the medicinal extract that relative density at 20 DEG C is 1.018 ~ 1.110；Medicinal extract Middle to add the ethanol that volume fraction is 85%, heating and refluxing extraction, is heated to reflux 2h for the first time, is heated to reflux 1.5h for the second time, the Be heated to reflux 1h three times, recycle merging filtrate, concentrate filtrate, obtain relative density at 20 DEG C and obtain medicinal extract for 1.12 ~ 1.14, to obtain the final product Extracting solution.
（2）14 parts of canarium pimela oil, 7 parts of Baeckea frutescens oils and 13 parts of eucalyptus oils are added in extracting solution, is thoroughly mixed, is made viscous Thick shape mixture, is sealed, up to canarium pimela rusting vulnerary.
A kind of canarium pimela rusting vulnerary 6 of embodiment 6
（1）27 parts of giant knotweeds, 29 portions of honeysuckles and 23 parts of sowthistle tasselflower herbs are taken, are put into crock, add medicinal material 11 times of water of weight, decocting 3 Secondary, each 1h, recycles filtrate, heating concentration filtrate, obtains the medicinal extract that relative density at 20 DEG C is 1.018 ~ 1.110；In medicinal extract The ethanol that volume fraction is 95% is added, heating and refluxing extraction, is heated to reflux 2.5h for the first time, is heated to reflux 1.5h for the second time, the Be heated to reflux 1h three times, recycle merging filtrate, concentrate filtrate, obtain relative density at 20 DEG C and obtain medicinal extract for 1.12 ~ 1.14, to obtain the final product Extracting solution.
（2）9 parts of canarium pimela oil, 4 parts of Baeckea frutescens oils and 9 parts of eucalyptus oils are added in extracting solution, is thoroughly mixed, is made sticky Shape mixture, is sealed, up to canarium pimela rusting vulnerary.
Embodiment 7
By carrying out clinical test for many years to canarium pimela rusting vulnerary of the present invention, case 1155, wherein male 589 are treated altogether Example, women 566,5 years old of age minimum, maximum 49 years old, be below clinical trial result：
Model case
Case 1：Sun, 6 years old, boy, at upper kindergarten, accidentally run into vacuum flask, had scalded instep, red and swollen, kindergarten After teacher's simple process, using canarium pimela rusting vulnerary of the present invention, fully recover after 3 days.
Case 2：Mr. Wang, 32 years old, man, certain factory electric welder, in once customary welding operation, accidentally touched welding head Arm is arrived, skin is burnt by high temperature immediately, and pain is incomparable, and fortunately burn surface area is not very big.Applied at once with burn medicine of the present invention Smear, fully recover after 4 days, preventing from scar.
Case 3：Lee, 44 years old, man, certain dining room chef.When cooking is eaten, since liquid gas storage tank connector is damaged, cause liquid Changing gas explosion to fry, Lee is by large-area burns, and burn surface area is up to 80%, and death is expected at any moment, after giving certain hospital's Emergency Medical Dept. to rescue, Affected part is smeared using burn medicine of the present invention, relieves pain after 3 days, subsides a swelling after 5 days, affected part is scabbed after 8 days, and affected part is fully recovered after 12 days, is not had Have and leave too big scar.
Case 4：Mr. Wang, female, 14 years old, certain junior middle school student, went to open water at noon during meal, and imprudence tap ruptures, Arm has been scalded, it is immediately red and swollen, then start to deteriorate.Teacher sends in a hurry hospital and handles, and after simple process, uses the present invention to burn Vulnerary, fully recovers after 4 days, and process no pain, swelling and pain relieving is fast, and infection phenomenons do not occur.

Claims (3)

  1. A kind of 1. canarium pimela rusting vulnerary, it is characterised in that：It is made of the raw material of following parts by weight：8 ~ 15 parts of canarium pimela oil, Baeckea frutescens oil 3 20 ~ 30 parts of ~ 8 parts, 8 ~ 15 parts of eucalyptus oil, 20 ~ 30 parts of giant knotweed extracting solution, 20 ~ 30 parts of Flos Lonicerae extractive solution and sowthistle tasselflower herb extracting solution.
  2. 2. canarium pimela rusting vulnerary according to claim 1, it is characterised in that：It is made of the raw material of following parts by weight：Canarium pimela 10 parts of oil, 5 parts of Baeckea frutescens oil, 10 parts of eucalyptus oil, 25 parts of giant knotweed extracting solution, 25 parts of Flos Lonicerae extractive solution and sowthistle tasselflower herb extracting solution 25 Part.
  3. 3. the preparation method of the canarium pimela rusting vulnerary described in claim 1, it is characterised in that：Include the following steps：
    （1）The preparation of extracting solution：Giant knotweed, honeysuckle and sowthistle tasselflower herb are taken by above-mentioned parts by weight, is put into crock, adds medicinal material weight 8 ~ 12 times of water are measured, decocting 3 times, 1 ~ 1.5h, recycles filtrate, heating concentration filtrate, it is 1.018 to obtain relative density at 20 DEG C every time ~ 1.110 medicinal extract；Add the ethanol that volume fraction is 85 ~ 95% in medicinal extract, heating and refluxing extraction, it is heated to reflux 2 for the first time ~ 3h, is heated to reflux 1.5h for the second time, is heated to reflux 1h for the third time, recycles merging filtrate, concentrates filtrate, obtains relatively close at 20 DEG C Spend and obtain medicinal extract for 1.12 ~ 1.14, up to extracting solution；
    （2）Canarium pimela oil, Baeckea frutescens oil and the eucalyptus oil of above-mentioned parts by weight are added in extracting solution, is thoroughly mixed, is made viscous Thick shape mixture, is sealed, up to canarium pimela rusting vulnerary.
CN201711258895.9A 2017-12-04 2017-12-04 A kind of canarium pimela rusting vulnerary and preparation method thereof Pending CN107898832A (en)

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Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002007745A1 (en) * 2000-07-26 2002-01-31 Yuuzou Tsuchida Antipruritic compositions and compositions promoting wound healing
CN106606524A (en) * 2016-12-06 2017-05-03 苏州健雄职业技术学院 Burn and scald injury ointment and preparation method and application thereof
CN107260850A (en) * 2017-06-07 2017-10-20 广西源安堂药业有限公司 The Chinese medicine preparation and its production method of a kind of digestive discomfort inner disease outer treat

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Publication number Priority date Publication date Assignee Title
WO2002007745A1 (en) * 2000-07-26 2002-01-31 Yuuzou Tsuchida Antipruritic compositions and compositions promoting wound healing
CN106606524A (en) * 2016-12-06 2017-05-03 苏州健雄职业技术学院 Burn and scald injury ointment and preparation method and application thereof
CN107260850A (en) * 2017-06-07 2017-10-20 广西源安堂药业有限公司 The Chinese medicine preparation and its production method of a kind of digestive discomfort inner disease outer treat

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Application publication date: 20180413