KR20110138459A - Herb medicine composition - Google Patents

Abstract

PURPOSE: A functional medical herb food composition, and a producing method thereof are provided to use the composition as an aiding agent for an anti-tubercular agent. CONSTITUTION: A functional medical herb food composition contains 1-25wt% of citrus unshiu, 1-25wt% of lampetra japonica, 1-25wt% of angelica sinensis, 1-25wt% of atractylodes japonica, 1-25wt% of paeonia lactiflora, 1-25wt% of liriope platyphylla, 1-25wt% of glycyrrhizae radix, 0-20wt% of schisandra chinensis, 0-20wt% of polygonatum sibiricum, 0-20wt% of cinnamomum loureirii, 0-20wt% of cnidium officinale, 0-20wt% of amomum xanthioides, 0-10wt% of mica, 0-10wt% of fritillaria verticillata, and 0-10wt% of sinapis alba.

Description

Functional herbal food composition {HERB MEDICINE COMPOSITION}

The present invention relates to a functional herbal food composition that can be used as an adjuvant to treat tuberculosis, and more particularly, isoniazid, rifampicin, pyrazinamide, ethambutol, and streptomycin. The present invention relates to a dietary supplement based on herbal ingredients that can be used as an adjunct to tuberculosis therapeutics and to treating tuberculosis using the same.

Much of the world's population is at risk of tuberculosis, and tuberculosis is one of the top ten causes of death in Korea. The treatment method is known to be treated with anti-tuberculosis drugs such as isoniazid (INH), rifampin (RFP), pyrazinamide (PZA), ethambutol (EMB), streptomycin (SM), but the cure rate is low. Long, there is a problem that the lung cells are petrified even after treatment and the lung function is lowered.

Therefore, there is a continuing need for a new adjuvant therapeutic agent that can enhance the therapeutic effect of anti-tuberculosis drugs, increase the cure rate, shorten the treatment period, prevent pulmonary cell calcification, and prevent lung function decline after treatment.

The problem to be solved in the present invention is to provide a new adjuvant therapeutic agent that can enhance the therapeutic effect of the anti-tuberculosis drug to increase the cure rate, shorten the treatment period, prevent pulmonary cell calcification and prevent the decrease of lung function after treatment .

Another problem to be solved in the present invention is to provide a new adjuvant therapy that can help to treat lung diseases such as pneumonia or lung cancer.

In order to solve the above problems, the present invention is 1-25% by weight of dermis, 1-25% by weight of seven-sea fish, 1-25% by weight of Angelica, 1-25% by weight, 1-25% by weight of Baek, Dongmunmun 1 -25 wt%, licorice 1-25 wt%, Schisandra chinensis 0-20 wt%, Astragalus 0-20 wt%, Broiler (cinnamon) 0-20 wt%, Cheongung 0-20 wt%, Civilian 0-20 wt% , 0-10% by weight of mica (defense), 0-10% by weight of the feather, characterized in that to provide a live ring consisting of 0-10% by weight of white field.

In the practice of the present invention, the ring closure is twice daily in adults with tuberculosis treatment agents such as isoniazid (INH), rifampin (RFP), pyrazinamide (PZA), ethambutol (EMB), streptomycin (SM) The dose is in the range of 100 g / dose, more preferably in the range of 10-50 g / dose.

In the practice of the present invention, the live ring is 1-25% by weight, 1-25% by Count, 1-25% by weight, 1-25% by weight, 1-25% by weight, Astragalus 1-25 It is better to take with active acid consisting of 0% by weight, 0-20% by weight of bark, 0-20% by weight of flakes, 0-20% by weight of clove, 0-20% by weight of white sand and 0-20% by weight of licorice.

In the practice of the present invention, the active acid is taken in a 5-100 g / dosing range twice a day with a live ring, more preferably in the 10-50 g / dosing range.

In the present invention, the baekryeul used in the live ring and the live acid is a perennial herb of the perennial herb belonging to the Asteraceae, which has inherent scent as a medicine that helps digestion and diuretic action, but is not limited in theory, Anti-inflammatory effect [Chem. Pham. Bull., 27 (12), 2965, 1979] as an adjunct to tuberculosis treatment.

In the present invention, the Baekjak (白). Paeonia japonica) used in the ring-open ring and the acid is a plant whose roots are thick and fleshy and the bottom is covered with scale-like leaves, the body (의) and 血 ( It is used when blood) is broken together. Although not theoretically limited, in the present invention, the earl medicament is used as an adjuvant of tuberculosis treatment as a medicine that harmonizes the negative and positive states of the body during treatment.

In the present invention, the licorice used for the live ring and the live acid can be purchased commercially available from conventional materials sold on medicinal herbs.

In the present invention, the Astragalus used for the Lung ring and Lung acid is a perennial plant belonging to the legumes, and enhances the biological capacity, diuretic action and blood pressure lowering action, blood vessel expansion and improvement of blood circulation and nutrition, heart Strong against the weakness is excellent. In the present invention, although not limited in theory, it is used as an adjuvant of tuberculosis treatment for blood pressure, drainage (preventing pus), and tonic blood.

In the present invention, the cheonunggung used in the live ring and live mountain is a perennial herb of the mountain cultivars, and grows up to 30-60 cm in height, the root stem is a thick, hairless material as a whole, soothing, analgesic and tonic It contains coumarin and mannitol in the horoscope and contains 1 ~ 2% of essential oils such as knidylide, neoctilide, liqueuside, cheongung acid, butylphthalide and cheongung acid ester. It is. In the present invention, the uterus is not limited in theory, but is used as an adjuvant for the treatment of tuberculosis as a medicine for analgesic and sedation.

In the present invention, the dermis used in the ring-closure is dried tangerine peel, and is not limited in the present invention, but is used for promoting digestion, clearing the phlegm and controlling cough.

In the present invention, the chilsung fish used in the live ring is a kind of eel, a chilsung fish called chilsung fish.

In the present invention, the donkey used in the ring lung is commercially available as one of the most commonly used material in the clinical, and is not limited in the present invention, but theoretically limited, blood circulation, internal bleeding, blood flow stagnation It is used to solve this problem.

In the present invention, the Liriope Tuber used in the ring-closure ring (Liriope Tuber) is a perennial root of the perennial root of the perennial root (Liriope platyphylla Wanget Tang) or lobular vegetation (Ophiopogon japonicus Ker-Gawler) The bulge of the root. Although not theoretically limited in the present invention, the pulmonary dong includes various chemical components as described in Korean Patent Laid-Open No. 2003-0004040, and is not theoretically limited in the present invention, but is used to assist in treating pulmonary tuberculosis.

In the present invention, the Schizandra chinensis used in the ring-closing ring can be purchased and used commercially as known medicines. In the present invention, the Schizandra Chinensis is a deciduous woody plant belonging to the Magnolia family, which is cultivated for ornamental or medicinal use, blooms in June-August, and has a reddish round fruit after flowering. Schisandra chinensis is known for its five flavors, bitter, sour, sweet, spicy, and salty, called Schisandra chinensis (五味子) and is known to be rich in vitamins A and C. Various pharmacological functions of Schisandra chinensis have been reported and have been used as herbal medicine since ancient times.

In the present invention, the broiler (cinnamon) used in the ring-closure is a plant name is Cassia, and the herbal name is cinnamon (cassiae cortkex), broiler (cinnamomi) as described in the reference 10-2004-0046309 cortex), presence, branch, scientific names Cinnamomum cassia, Cinnamomum loureitii. In Chinese medicine, cinnamon and cinnamon are used as medicines. Cinnamon is the bark of cassia, and broiler used to refer to the bark of cinnamon, but the cinnamon (stalk bark), cinnamon (bark) and superficial layer of cinnamon Somewhat removed, commonly used as cinnamon. Presence takes only the central part by removing the outer surface of the broiler and removing the inner skin. Gage is the thinnest, thinnest and softest of the branches of cassia. Cinnamon is a warm, nontoxic drug. The main ingredient of cinnamon is essential oil called cinnamon oil, which is cinnamic aldehyde, camphene cineol, linalool, eugenol, sugar, fat, phosphorus, iron, vitamin It contains ingredients such as A, B1, and B2. It stimulates the gastrointestinal mucosa, stimulates secretion, suppresses cramping pain in the stomach, promotes the movement of the gastrointestinal tract, and releases gas and improves absorption. In addition, cinnamon stimulates nerves, promotes blood circulation, warms the body, and has an antiseptic effect that suppresses abnormal fermentation in the intestines. Cinnamic aldehydes in cinnamon have persistent peripheral vasodilation (hypertension) and platelet aggregation inhibition, and other perspiration and clay action. Commonly used for colds, pain and pain. The basin of the cassia tree is particularly strong heart and promote blood circulation, so weak people with common sense. In addition, the cinnamon extract has an antimicrobial activity that suppresses the decay of food, and the effect of cinnamon extract on the skin is not only to prevent hair loss when using the skin of the cinnamon on the head, but also to prevent hair loss, to remove the itch, to repair the wound It is also known to regulate congestion. Cinnamon concentrate is said to have a strong anti-inflammatory effect on the scalp, and when sprayed on the scalp from the outside, it removes wounds and inflammation of the scalp and prevents whitening to prevent white hair. In addition, cinnamon was found to have a lethal effect on the harmful bacterium E. Coil O157: H7. Researchers at Kansas State University have demonstrated antimicrobial activity using apple juice and cinnamon heavily contaminated with the bacteria. In the practice of the present invention, the cinnamon is not limited in theory, but exhibits antibacterial properties and is used as an adjuvant for treating tuberculosis.

In the present invention, the construction worker used for the ring-back ring is a perennial herb of the monocotyledonous plant Ginger, Gingeraceae, scientific name is Amomum xanthoides, the stem is about 2m high and the leaf looks like a red vinegar leaf. Bottom is wrapped around each other and pointed end. In the practice of the present invention, the construction worker is not limited in theory, but serves as an adjuvant for treating tuberculosis while functioning as an aromatic dry agent, a gust and an extinguishing agent.

In the present invention, the mica used in the live ring is flat and tasteless and has no poison, and is a medicine that makes the breath better and weaker. It is thin and light like a cicada wing. It can be used in various ways and can be purchased commercially. In the practice of the present invention, the mica is respiratory, so the properties are flat, the taste is sweet, and there is no poison. In the practice of the present invention, it is used as an adjuvant for the treatment of tuberculosis to prepare breathing.

In the present invention, the hair follicle used in the ring ring is the name Fritillaria verticillata Will, English name is A checkered lily is a perennial herb belonging to the family Liliaceae (Lillaceae), the leaves are long line-shaped, the diameter of the root is white It is a spherical sphere with many bumps. A flower comes out at the end of the stem, and it is purple and blooms around May. Pemo is peeled off the outer shell of the outer shell and used for medicinal purposes, the component contains alkaloids, such as fritline (fritilline), fritillarine (verticine), beticillin (verticilline), etc. and glycosides such as peimine and peiminoside. In the present invention, the famo is an antitussive expectorant that is effective for acute bronchitis, bronchial asthma, seawater caused by cold, and the pharmacological action of hydrochloric acid, which significantly inhibits the respiratory and seawater centers, resulting in the effect of the antitussive effect. To generate. In the present invention, the hair loss is not theoretically limited, but is used as an adjuvant for treating tuberculosis that acts on seawater, hemoptysis, chest pain, and sore throat as an antitussive expectorant.

In the present invention, the white chicken used in the ring-closure ring tinnitus dog (芥子), yellow dog (黄 芥子), palates (胡 芥子), white dog (白 芥) and the scientific name Sinapis alba (L.) Mature seeds of mustard and gad, which are annual or adult herbs. The form of medicinal herbs is 1.5 ~ 2.5㎜ in diameter, the surface is pale yellow with net pattern, and the seedling is thin and fragile. The mature fruit is collected in summer and autumn, and the seeds are taken and dried in the sun. In the practice of the present invention, the white leucine is not limited in theory, but stops coughing or asthma, stops bloating, stuffiness and pain, and is effective in chronic bronchitis or bronchial dilatation, and is used as an adjuvant for treating tuberculosis.

In the present invention, the Coicis Semen used in the active acid (Coicis Semen) is a seed of Yulmu (Coix lacryma-jobi var. Mayuen Stapf), dry drift, blue heat drainage (등), etc. There is the effect of diuretic, tonic, analgesic, anti-inflammatory effect. Although not limited in theory, the right ear is used as an adjuvant of tuberculosis treatment to prevent side effects such as edema, neuralgia, rheumatism, bladder stones, and the like during treatment.

In the present invention, the Moutan Cortex Radicis used in the active acid is a peony (Paeonia suffruticosa) root bark in the root of paeonol (paeonol), paeoonoside (paeonoside), paeonolide (paeonolide), pae It contains paeoniflorin. The neck bark is not limited in theory, but is used as an adjuvant of tuberculosis treatment for its antimicrobial effect.

In the present invention, the engraver used in the active acid is thorns, leaves and the like obtained from the gliding tree (Gleditschia officinalis). It is a deciduous arborescent tree belonging to Legumes (Leguminosae) native to China. It is 15 m high, reddish brown, thick and thorny. Leaves are superior bilobal, with 4-7 pairs of lobules. Lobules are egg-shaped, egg-shaped lanceolate, and oval-shaped. Leaf bottoms are round or wedge-shaped, with dull dimples on the edges, and flowers are mixed, with hyacinths or aquatic inflorescences. Calyxes are bell-shaped, lobes are 4, egg-shaped lanceolate. Engraver is effective in treating shame and intestinal tract in Tokyeongchocho, and it is effective in treating chifeng fever, Jongpok, and large intestinal herb in herbal wood. In medical introductory, it is said to cure five winds. In the present invention, the engraver is not limited in theory, but is used as an adjuvant of tuberculosis treatment for antitumor, antipyretic, anti-inflammatory and antibacterial action.

In the present invention, the clove used for the active acid is the scientific name Eugenia caryophyllata, the herbal name is Caryophlii flos, which is not yet bud of the clove. The clove has a dark brown or dark red color with 10 to 18 mm long hilly burns, 4 thick calyxes and membranous stools above, with a peculiar smell and a strong taste and later numb the tongue. Representative main components of the clove are eugenol (70 to 85%), and besides, acetogenol, gallotic acid, β-carophyllene, 2-hydroxy4, 6-dimethoxy, 5-methylacetophenone and the like It contains. In the present invention, the clove is not limited in theory, but is used as an anticoagulant effect as an anti-coagulant as a component of a co-formulation and is an adjuvant for tuberculosis treatment used as a natural anticoagulant.

In the present invention, the baekhwasa has the effect of driving out the wind and the meridians and relieve convulsions. In the present invention, the baekhwasa is not limited in theory, but is used as an adjuvant of tuberculosis treatment so that the meridians may be circulated to soothe spasms and the like.

In the present invention, the ring-opening ring or the ring-opening acid composition is not limited to the ring or acid form as a composition for oral administration, and may be prepared in various forms as possible. In another embodiment of the present invention, it can be consumed by various methods such as decoctions, extracts, ground products, pills.

In the practice of the present invention, the manufacture of a pill form is to prepare a Chinese medicine in a solid pill (pill) according to a known method to minimize the odor and convenience for storage and drinking, herbal medicine material After pulverizing is added to the appropriate extender (extender) to prepare agglomerates in the form of granules. In this case, the extender functions as a binder to aggregate the insufficient viscosity of the powder into granules, and serves as a dilution function for concentration control.

In another aspect of the present invention, the live ring or live lung according to the present invention can be used as an adjuvant therapeutic agent for diseases related to lung function, for example, pneumonia or lung cancer.

Functional herbal composition according to the present invention can be used as an adjuvant therapeutic agent to help the treatment of tuberculosis patients by enhancing the function of the lungs. In addition, the functional herbal composition according to the present invention can be effectively used for the treatment of other diseases related to the lung, for example, pneumonia or lung cancer.

Example 1

Baekchul 10%, Baekjakak 10% by weight, Cheongung 15% by weight, Licorice 5% by weight, Dermis 10% by weight, Chilsung fresh fish 5% by weight, Angelica 5% by weight, Macmundong 5% by weight, Schisandra chinensis 5%, Astragalus 5% by weight , 5% by weight of broiler (cinnamon), 5% by weight of construction workers, 5% by weight of mica (defense), 5% by weight of famo, 5% by weight of 100% mixture of the mixture and 100 parts by weight of the extender to prepare a ring, Patients treated with isoniazid were orally administered 40 g of pills twice daily. Ten control patients were treated only with isoniazid and the like, and no pill was administered. After receiving a complete cure, control periods and the function of lung cells were examined. Pulmonary cell function was determined by x-ray imaging to determine whether it was petrified.

patient Treatment period Lung cell function Administration group 3 months No waste petrification Control group 6 months In waste stone

Example 2

Patients diagnosed with severe pulmonary tuberculosis and treated with isoniazid, etc., 10% by weight, 10% by weight, 10% by weight, 15% by weight, licorice 5%, 10% by weight, Euiin 20%, 5% by weight of bark, 5 Live waste acid consisting of 10% by weight, 10% by weight of clove, and 10% by weight of white sand was orally administered 50 g each twice daily with the live ring disclosed in Example 1. Ten control patients were treated only with isoniazid and the like and were not given hwan and acid. After receiving a complete cure, control periods and the function of lung cells were examined. Pulmonary cell function was determined by x-ray imaging to determine whether it was petrified.

patient Treatment period Lung cell function Administration group 4 months No waste petrification Control group 7 months In waste stone

Claims (5)

1-25 wt% dermis, 1-25 wt% Chilsung Fish, 1-25 wt% Angelica, 1-25 wt% Baekchul, 1-25 wt% Baekjak, 1-25 wt% Megmundong, 1-25 wt% Licorice, Schisandra 0-20 wt%, Astragalus 0-20 wt%, Broiler (cinnamon) 0-20 wt%, Cheongung 0-20 wt%, Construction worker 0-20 wt%, Mica (defense) 0-10 wt%, Famo A live ring consisting of 0-10% by weight and 0-10% by weight of white. Whitening 1-25%, Earl 1-25%, Euiin 1-25%, Cheongung 1-25%, Astragalus 1-25%, Bark skin 0-20%, Engraver 0-20%, Cloves Active waste acid consisting of 0-20% by weight, 0-20% by weight of white sand and 0-20% by weight licorice. A method for treating lung disease according to claim 1 to a patient diagnosed with pulmonary tuberculosis and treated with isoniazid or the like. The treatment according to claim 3, wherein the patient is diagnosed with severe pulmonary tuberculosis and treated with isoniazid or the like, and the active lung acid according to claim 2 is additionally taken as an adjuvant therapy. Way. A treatment method comprising administering a live lung ring according to claim 1 alone or with a live lung acid according to claim 2 to a patient diagnosed with lung disease such as pneumonia or lung cancer.