CN107174560B - Mild moisturizing and relieving cleansing water and preparation method thereof - Google Patents
Mild moisturizing and relieving cleansing water and preparation method thereof Download PDFInfo
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- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
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- A61K8/00—Cosmetics or similar toiletry preparations
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- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/84—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions otherwise than those involving only carbon-carbon unsaturated bonds
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- A61Q19/10—Washing or bathing preparations
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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Abstract
The invention discloses a mild moisturizing and relieving cleansing water. The cleansing water comprises the following raw material components in percentage by mass: 3-15% of nonionic surfactant, 8-18% of moisture-keeping functional component, 3-10% of soothing functional component, 0.01-0.05% of citric acid, 0.02-0.1% of sodium citrate, 0.15-0.25% of polyaminopropyl biguanide and the balance of water. The nonionic surfactant used by the makeup remover disclosed by the invention has the effects of quick makeup dissolving and mild makeup removing through compounding in different proportions. The moisturizing effective component used by the makeup remover can effectively repair skin barriers and achieve the moisturizing effect. In addition, the soothing functional component used by the cleansing water disclosed by the invention has the effects of mildness, sedation and soothing.
Description
Technical Field
The invention relates to a makeup remover composition, belongs to the technical field of cosmetics, and particularly relates to a mild moisturizing and relieving makeup remover and a preparation method thereof.
Background
In recent years, makeup removal products are favored by people due to the rise of the makeup market. The makeup removing products on the market mainly take makeup removing oil and makeup removing water as main materials. The makeup removing oil mainly utilizes the characteristic of similarity and intermiscibility between grease, takes the oil as a solvent, dissolves color makeup or dirt on the face, and has high-efficiency and thorough makeup removing effect. However, the skin feel is thick and greasy when the skin care product is used, and pores can be blocked once the skin care product is not cleaned in time, so that skin problems such as acne and comedo are caused. The makeup remover mainly comprises water and a surfactant, and is used for removing makeup by the principle of micelle solubilization, so that the makeup remover is fresh in texture, simple and easy to use, and is more popular with young people.
At present, the makeup remover on the market mainly takes PEG-6 caprylic/capric glycerides as makeup removing components, and has high makeup dissolving speed and good makeup removing effect. Although the makeup remover is excellent in makeup removal effect, it has problems of large irritation, dry skin after makeup removal, and excessive degreasing power.
Chinese patent CN104490680A proposes a mild moisturizing cleansing water and a preparation method thereof. The makeup removing component is single PEG-6 caprylic/capric glycerides, and moisture-keeping components such as trimethylglycine, polyglutamic acid and the like are added, so that the problem of overlarge degreasing force after makeup removing is solved.
Chinese patent CN104000745B proposes a spray makeup remover which has no stimulation to eyes and a preparation method thereof. The makeup removing composition is single poloxamer 184, and a plurality of glucose soothing agents are added, so that the mildness of the product is well ensured, but the makeup removing effect is slightly insufficient.
Aiming at the defects of the prior art, the invention aims to develop mild moisturizing and relieving cleansing water and a preparation method thereof so as to meet various market requirements.
Disclosure of Invention
The invention aims to provide the makeup remover which is good in makeup removing effect, safe, mild, and mild in moisture retention and the preparation method thereof.
In order to solve the problems, the invention adopts the following technical scheme:
the mild moisturizing and relieving cleansing water comprises the following raw material components in percentage by mass:
3-15% of nonionic surfactant;
8-18% of a moisturizing effective component, wherein the moisturizing effective component is a combination of an alcohol humectant, a saccharide humectant and a plant extract humectant;
3-10% of a relieving functional component, wherein the relieving functional component is any three or four of a sophora flavescens root extract, hamamelis virginiana, a white-flower spring yellow chrysanthemum extract and a tea extract;
0.01 to 0.05 percent of citric acid, 0.02 to 0.1 percent of sodium citrate, 0.15 to 0.25 percent of poly aminopropyl biguanide and the balance of water.
Preferably, the mild moisturizing and soothing cleansing water comprises the following raw material components in percentage by mass: 5-12% of nonionic surfactant;
10-15% of a moisturizing effective component, wherein the moisturizing effective component is a combination of an alcohol humectant, a saccharide humectant and a plant extract humectant;
5-10% of a relieving functional component, wherein the relieving functional component is any three or four of a sophora flavescens root extract, hamamelis virginiana, a white-flower spring yellow chrysanthemum extract and a tea extract;
0.01 to 0.05 percent of citric acid, 0.02 to 0.1 percent of sodium citrate, 0.15 to 0.25 percent of poly aminopropyl biguanide and the balance of water.
The mild moisturizing and relieving cleansing water disclosed by the invention has the beneficial effects that the nonionic surfactants are any three or four of PEG-6 caprylic acid/capric acid glycerides, poloxamer 184, PEG/PPG-17/6 copolymer and xylitol-based glucoside.
The alcohol humectant is 8% of dipropylene glycol, the saccharide humectant is 0.5% of trehalose, and the plant extract humectant is one or two of an ophiopogon root extract and a twisted cactus stem extract.
The invention also provides a preparation method of the cleansing water, which comprises the following steps:
1) weighing the component A according to the mass percentage: deionized water and nonionic surfactant, and stirring and mixing uniformly.
2) Weighing the component B according to the mass percentage: moisture-keeping functional components for later use.
3) Weighing the component C according to the mass percentage: relieving the functional components for later use.
4) Heating the component A to 80-85 ℃, preserving heat, stirring for 30 minutes, and then cooling.
5) Cooling to 45 ℃, adding B, C components and the rest of the components D: the preparation method comprises the following steps of stirring the components of the polyaminopropyl biguanide, the citric acid and the sodium citrate until the components are uniform and transparent.
The properties of the important raw materials used in the invention are as follows:
PEG-6 caprylic/capric glycerides are water-soluble liquids with surface activity, are used as fat-imparting agents and solubilizers in cosmetic and pharmaceutical formulations, have an HLB value of 19, are used in makeup remover, and are used as surfactants, can dissolve various oils and fats, can make makeup fall off easily, and are therefore widely applied.
Poloxamer 184, a block copolymer of ethylene glycol and propylene glycol, is commonly used in pharmaceuticals, for example in parenteral and oral preparations for intravenous injection. The product has high mildness and safety, and is widely used as an emulsifier in cosmetics to oral care products.
The PEG/PPG-17/6 copolymer is a water-soluble mild nonionic surfactant, is often used as a sticky feeling remover in skin care products, and is particularly suitable for solvents of eye makeup removing products.
The xylitol-based glucoside also has certain surface activity, is prepared by synthesizing glucose and xylitol, has small stimulation to skin, is safe, has obvious thickening, tackifying and detergency power, and has very good tolerance. The natural plant moisturizer has excellent skin tendering and relieving effects, and can reduce skin discomfort and relieve external irritation.
The radix ophiopogonis extract is derived from radix ophiopogonis, is rich in polyfructose active ingredients, has strong drought resistance, and can reduce the disintegration of stratum corneum by strengthening the adhesion of the upper layer of epidermis and recombining the barrier function of skin to achieve the moisturizing effect.
An extract of the stem of Opuntia Dillenii belonging to the family of desert plants of the order Caryophyllales. In order to adapt to the water-deficient climate of desert, the leaves evolve into short thorns to reduce the evaporation of water. The twisted cactus has good antioxidation, also has remarkable effects of high-efficiency water replenishing and radiation protection, ensures high nutrition, high purity and high activity of natural organic functional components, and prevents skin from being damaged by ultraviolet rays and radiation of computers, televisions and mobile phones.
Sophora flavescens ait root extract is an alkaloid extracted from Sophora flavescens ait of Sophora genus of Leguminosae family. Is cold in nature, has the effects of clearing heat, eliminating dampness, resisting inflammation, relieving itching, balancing lipid secretion, dredging and astringing pores, removing toxin impurities in skin, promoting the growth and repair of damaged vascular nerve cells, and recovering the activity of subcutaneous capillary cells.
Hamamelis virginiana has antiinflammatory, tranquilizing, soothing, and soothing effects in cosmetics, and can relieve irritated skin, promote lymph blood circulation, regulate sebum secretion, and improve chap, sunburn, and acne. The skin can be comprehensively adjusted from inside to outside, the pH value and the grease secretion of the skin are balanced, pores are purified, the damaged skin is repaired, the dilated pores are effectively adjusted, the coarse pores are obviously converged, blackheads and acnes are prevented from being generated, and the skin is enabled to quickly present a fine, smooth and compact state.
The extract of the white-flower spring yellow chrysanthemum is sweet and fragrant, can improve eyesight, reduce liver fire, treat insomnia and reduce blood pressure. Has good effects of relieving allergy, relieving pain, diminishing inflammation, repairing sensitive skin, resisting external stimulation, reducing thin red blood streak, reducing redness, adjusting uneven skin color and the like.
The tea extract is rich in 500 biochemical components such as tea polyphenol (catechin), vitamins, mineral elements, amino acids, etc. Because tea polyphenol has astringency and can denature protein precipitate, tea polyphenol has inhibiting and killing effects on various bacteria such as staphylococcus aureus, freund dysentery bacterium, typhoid dysentery bacterium, pseudomonas aeruginosa, bacillus subtilis and the like, and the tea is used for washing wounds and treating scalds in folk, namely, the astringency sterilization and inflammation diminishing effects of tea polyphenol are utilized to promote wound healing.
The invention has the beneficial effects that:
1) the nonionic surfactant composition used in the invention has the advantages of high makeup dissolving speed, good makeup removing effect and wider application range. By optimizing the compounding ratio of the nonionic surfactant, the irritation of PEG-6 caprylic/capric glycerides can be obviously reduced.
2) The moisturizing and soothing cleansing water has the moisturizing, soothing and calming effects, further reduces the irritation of the surfactant to the skin, and can reduce red blood filaments and alleviate irritated skin.
3) The technical scheme of the invention is used as a whole in a mutually matched way, and the final formula achieves the effects by optimizing the content of the components.
Detailed Description
The technical solution of the present invention is further specifically described below by combining the effect test examples with specific preferred embodiments, but the present invention is not limited to the following embodiments.
Example 1
The mild moisturizing and relieving cleansing water comprises the following raw material components in percentage by mass:
a: nonionic surfactant:
4% of PEG-6 caprylic/capric glycerides, 1841% of poloxamer, 2% of PEG/PPG-17/6 copolymer and the balance of water.
B: moisture retention functional components:
8% of dipropylene glycol, 0.5% of trehalose and 1.5% of radix ophiopogonis extract.
C: the components with the relieving effect are as follows: 1% of sophora flavescens root extract, 0.8% of hamamelis and 1.5% of white-flower spring yellow chrysanthemum extract.
D: the rest components are as follows:
0.01 percent of citric acid, 0.03 percent of sodium citrate and 0.2 percent of polyaminopropyl biguanide.
Example 2
The mild moisturizing and relieving cleansing water comprises the following raw material components in percentage by mass:
a: nonionic surfactant:
4% of PEG-6 caprylic/capric glycerides, 1841% of poloxamer, 2% of xylitol-based glucoside and the balance of water.
B: moisture retention functional components:
8% of dipropylene glycol, 0.5% of trehalose, 1.5% of radix ophiopogonis extract and 0.5% of prickly pear extract.
C: the components with the relieving effect are as follows: 1.5 percent of sophora flavescens root extract, 1.5 percent of chrysanthemum flower in white flower spring and 0.5 percent of tea extract.
D: the rest components are as follows:
0.01 percent of citric acid, 0.03 percent of sodium citrate and 0.2 percent of polyaminopropyl biguanide.
Example 3
The mild moisturizing and relieving cleansing water comprises the following raw material components in percentage by mass:
a: nonionic surfactant:
3% of PEG-6 caprylic/capric glycerides, 1842% of poloxamer, 3% of PEG/PPG-17/6 copolymer, 2% of xylitol-based glucoside and the balance of water.
B: moisture retention functional components:
8% of dipropylene glycol, 0.5% of trehalose, 1.5% of radix ophiopogonis extract and 1% of prickly pear extract.
C: the components with the relieving effect are as follows: 1.5% of sophora flavescens root extract, 1% of hamamelis virginiana, 2% of chamomile extract and 1% of tea extract.
D: the rest components are as follows:
0.01 percent of citric acid, 0.03 percent of sodium citrate and 0.2 percent of polyaminopropyl biguanide.
Example 4
The mild moisturizing and relieving cleansing water comprises the following raw material components in percentage by mass:
a: nonionic surfactant:
4% of PEG-6 caprylic/capric glycerides, 1842% of poloxamer, 2% of PEG/PPG-17/6 copolymer, 2% of xylitol-based glucoside and the balance of water.
B: moisture retention functional components:
8% of dipropylene glycol, 0.5% of trehalose, 1.5% of radix ophiopogonis extract and 1% of prickly pear extract.
C: the components with the relieving effect are as follows: 1.5% of sophora flavescens root extract, 1.5% of hamamelis virginiana, 2.5% of chamomile extract and 1.5% of tea extract.
D: the rest components are as follows:
0.01 percent of citric acid, 0.03 percent of sodium citrate and 0.2 percent of polyaminopropyl biguanide.
Example 5
The mild moisturizing and relieving cleansing water comprises the following raw material components in percentage by mass:
a: nonionic surfactant:
4% of PEG-6 caprylic/capric glycerides, 1842% of poloxamer, 2% of PEG/PPG-17/6 copolymer, 2% of xylitol-based glucoside and the balance of water.
B: moisture retention functional components:
8% of dipropylene glycol, 0.5% of trehalose, 3.5% of radix ophiopogonis extract and 2% of prickly pear extract.
C: the components with the relieving effect are as follows: 2% of sophora flavescens root extract, 2% of hamamelis virginiana, 2.5% of chamomile extract and 2.5% of tea extract.
D: the rest components are as follows:
0.01 percent of citric acid, 0.03 percent of sodium citrate and 0.2 percent of polyaminopropyl biguanide.
The makeup remover described in examples 1 to 5 above was prepared as follows:
1) weighing the component A according to the mass percentage: deionized water and nonionic surfactant, and stirring and mixing uniformly.
2) Weighing the component B according to the mass percentage: moisture-keeping functional components for later use.
3) Weighing the component C according to the mass percentage: relieving the functional components for later use.
4) Heating the component A to 80-85 ℃, preserving heat, stirring for 30 minutes, and then cooling.
5) Cooling to 45 ℃, adding B, C components and the rest of the components D: the preparation method comprises the following steps of stirring the components of the polyaminopropyl biguanide, the citric acid and the sodium citrate until the components are uniform and transparent.
Comparative example 1:
the makeup remover comprises the following components in percentage by mass:
a: nonionic surfactant component:
7% of PEG-6 caprylic/capric glycerides and the balance of water.
B: moisture retention functional components:
8% of dipropylene glycol and 0.5% of trehalose.
C: the components with the relieving effect are as follows:
1.5 percent of Hamamelis virginiana.
D: the rest components are as follows:
0.01 percent of citric acid, 0.03 percent of sodium citrate and 0.2 percent of polyaminopropyl biguanide.
Comparative example 2:
the makeup remover comprises the following components in percentage by mass:
a: nonionic surfactant component:
5% of PEG-6 caprylic/capric glycerides, 1842% of poloxamer, and the balance of water.
B: moisture retention functional components:
8% of dipropylene glycol and 0.5% of trehalose.
C: the components with the relieving effect are as follows:
1.5 percent of Hamamelis virginiana and 2.5 percent of white-flower spring yellow chrysanthemum extract.
D: the rest components are as follows:
0.01 percent of citric acid, 0.03 percent of sodium citrate and 0.2 percent of polyaminopropyl biguanide.
The makeup remover of comparative examples 1 to 2 was prepared in the same manner as in examples 1 to 5.
For comparison, the makeup remover formulations of the respective examples and comparative examples are shown in table 1 below.
TABLE 1 cleansing water formulations of examples 1-5 and comparative examples 1-2
1. Effect embodiment: physical and chemical testing
The makeup remover of examples 1-5 was subjected to physical and chemical tests, the specific test methods are well known to those skilled in the art and will not be described herein. The test results were as follows:
appearance: a colorless transparent liquid; pH value: 5.0-7.0; heat stability at 45 ℃ for 24 h: qualified; cold resistance stability-10 ℃ 24 h: and (4) passing.
The results show that the makeup remover has qualified physical and chemical indexes and good heat resistance, cold resistance and stability.
2. Effect embodiment: safety test
Selecting 30 volunteers, placing about 0.020-0.025mL of a test object of each embodiment of the invention and a blank control group (deionized water) in a spot tester by a closed spot test method, externally applying a medical adhesive tape to the left back and the right back of the test object, removing the test object after 24 hours, observing skin reactions 0.5h, 24h and 48h after the spot patch is removed respectively, and recording the results according to the skin reaction grading standard in technical Specification for safety of cosmetics (2015).
Compared with the control group, after the product of the invention is coated for 0.5h, 24h and 48h, no allergic phenomena such as skin redness or erythema and the like appear, which indicates that the makeup remover prepared by the embodiments of the invention is safe and does not cause any adverse phenomenon.
3. Effect embodiment: makeup removal effect test
10 testers were selected for each sample, the makeup remover in each of examples 1-5 and comparative examples 1-2 was used for removing facial makeup, the feedback of the testers was recorded, and the makeup removal test results are shown in table 2.
TABLE 2 cosmetic removal Effect test of examples and comparative examples
From the results of table 2, it can be seen that: 80% of the testers consider the makeup removing effect of the example 1 to be good, and 20% of the testers consider the makeup removing effect of the example 1 to be general; 90% of the testers consider the makeup removing effect of the example 2 to be good, and 10% of the testers consider the makeup removing effect of the example 2 to be general; the makeup removal effect of examples 3, 4, 5 and comparative examples 1, 2 was considered good by 100% of the testers.
4. Effect embodiment: moisture retention effectiveness test (7 days)
20 testers were selected for each sample, the makeup remover in each of examples 1-5 and comparative examples 1-2 was used for removing facial makeup, the feedback of the testers was recorded, and the makeup removal test results are shown in table 3.
TABLE 3 moisturizing Effect test (7 days) of examples and comparative examples
From the results of table 3, it can be seen that: 75% of testers consider the moisturizing effect of the makeup remover water in the example 1 after makeup removal to be good, and 25% of testers consider the moisturizing effect of the makeup remover water in the example 1 after makeup removal to be general; 80% of testers consider that the moisturizing effect of the makeup remover water in the example 2 after makeup removal is good, and 20% of testers consider that the moisturizing effect of the makeup remover water in the example 2 after makeup removal is general; 90% of testers consider that the moisturizing effect of the makeup removing water of the examples 3 and 4 after makeup removal is good, and 10% of testers consider that the moisturizing effect of the makeup removing water of the examples 3 and 4 after makeup removal is general; 95% of testers consider that the moisturizing effect of the makeup remover water in the example 5 after makeup removal is good, and 5% of testers consider that the moisturizing effect of the makeup remover water in the example 5 after makeup removal is general; 40% of testers consider that the moisturizing effect of the cleansing water of the comparative example 1 after makeup removal is general, and 60% of testers consider that the moisturizing effect of the cleansing water of the comparative example 1 after makeup removal is poor; 5% of testers consider that the moisturizing effect of the cleansing water of the comparative example 2 after makeup removal is good, 45% of testers consider that the moisturizing effect of the cleansing water of the comparative example 2 after makeup removal is general, and 50% of testers consider that the moisturizing effect of the cleansing water of the comparative example 2 after makeup removal is poor;
5. effect embodiment: stimulation experiment of human eyes
10 test subjects were selected for each sample, the makeup remover water in each of examples 1 to 5 and comparative examples 1 to 2 described above was diluted to a 10% solution, and the test solution was dropped 2 drops to the left eye of the test subjects, and the sterilized deionized water was dropped 2 drops to the right eye of the test subjects. The instillation of both eyes was completed within 15 seconds, the feedback of the tester was recorded, and the test results are shown in table 4.
Table 4 irritation test of human eyes of each example and comparative example
From the results of table 4, it can be seen that: 70% of the testers did not irritate the makeup remover of example 1, and 30% of the testers considered the makeup remover of example 1 to be mild; 80% of the testers did not irritate the makeup remover of example 2, and 20% of the testers considered the makeup remover of example 2 to be mild; 90% of the testers did not irritate the makeup remover of example 3, and 10% of the testers considered the makeup remover of example 3 to be mild; 100% of the test subjects did not irritate the makeup remover according to examples 4 and 5; 80% of the testers considered that the cleansing water of comparative example 1 was not tolerable to severe irritation, 10% of the testers considered that the cleansing water of comparative example 1 was tolerable, and 10% of the testers considered that the cleansing water of comparative example was mild; the makeup remover of comparative example 2 was considered to be intolerable by 60% of the testers, intolerable by 30% of the testers, and mild by 10% of the testers.
The above 1-5 effect examples show that: according to the cleansing water provided by the embodiment of the invention, through optimized compounding of any three or four nonionic surfactants such as PEG-6 caprylic acid/capric acid glycerides, poloxamer 184, PEG/PPG-17/6 copolymer, xylitol-based glucoside and the like, and addition of moisturizing effective components formed by combining three types of humectants including alcohol moisturizers, saccharide moisturizers and plant extract moisturizers, any three or four types of soothing effective components such as a sophora flavescens root extract, hamamelis virginiana, a chamomile extract and a tea extract are further added on the basis, and on the premise of ensuring the cleansing effect of the product, the moisturizing property and the mildness of the product are improved to a great extent.
The above description is only a preferred embodiment of the present invention, and is not intended to limit the present invention in any way, so that any simple modification, equivalent change and modification made to the above embodiment according to the technical spirit of the present invention are within the scope of the technical solution of the present invention.
Claims (3)
1. The mild moisturizing and relieving cleansing water is characterized in that: the cleansing water comprises the following raw material components in percentage by mass:
7-10% of nonionic surfactant; the nonionic surfactant is any three or four of PEG-6 caprylic/capric glycerides, poloxamer 184, PEG/PPG-17/6 copolymer and xylitol-based glucoside;
8-18% of a moisturizing effective component, wherein the moisturizing effective component is a combination of an alcohol humectant, a saccharide humectant and a plant extract humectant; the alcohol humectant is 8% of dipropylene glycol, the saccharide humectant is 0.5% of trehalose, and the plant extract humectant is one or two of an ophiopogon root extract and a twisted cactus stem extract;
3-10% of a relieving functional component, wherein the relieving functional component is any three or four of a sophora flavescens root extract, hamamelis virginiana, a white-flower spring yellow chrysanthemum extract and a tea extract;
0.01 to 0.05 percent of citric acid, 0.02 to 0.1 percent of sodium citrate, 0.15 to 0.25 percent of poly aminopropyl biguanide and the balance of water.
2. The mild moisturizing soothing cleansing water of claim 1, wherein: the cleansing water comprises the following raw material components in percentage by mass:
7-10% of nonionic surfactant; the nonionic surfactant is any three or four of PEG-6 caprylic/capric glycerides, poloxamer 184, PEG/PPG-17/6 copolymer and xylitol-based glucoside;
10-15% of a moisturizing effective component, wherein the moisturizing effective component is a combination of an alcohol humectant, a saccharide humectant and a plant extract humectant; the alcohol humectant is 8% of dipropylene glycol, the saccharide humectant is 0.5% of trehalose, and the plant extract humectant is one or two of an ophiopogon root extract and a twisted cactus stem extract;
5-10% of a relieving functional component, wherein the relieving functional component is any three or four of a sophora flavescens root extract, hamamelis virginiana, a white-flower spring yellow chrysanthemum extract and a tea extract;
0.01 to 0.05 percent of citric acid, 0.02 to 0.1 percent of sodium citrate, 0.15 to 0.25 percent of poly aminopropyl biguanide and the balance of water.
3. A method of preparing a mild moisturizing soothing cleansing water according to claim 1 or 2, comprising the steps of:
1) weighing the component A according to the mass percentage: deionized water and a nonionic surfactant are stirred and mixed uniformly;
2) weighing the component B according to the mass percentage: moisture-preserving functional components for later use;
3) weighing the component C according to the mass percentage: relieving functional components for later use;
4) heating the component A to 80-85 ℃, preserving heat, stirring for 30 minutes, and then cooling;
5) cooling to 45 ℃, adding B, C components and the rest of the components D: the preparation method comprises the following steps of stirring the components of the polyaminopropyl biguanide, the citric acid and the sodium citrate until the components are uniform and transparent.
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CN111249217A (en) * | 2020-03-19 | 2020-06-09 | 西安润玉医疗科技有限公司 | Cleansing liquid for adjusting skin micro-ecological balance and preparation method thereof |
CN112137948A (en) * | 2020-11-11 | 2020-12-29 | 上海古腊国际贸易有限公司 | Antibacterial soothing toothpaste and preparation method thereof |
CN112656744A (en) * | 2020-12-30 | 2021-04-16 | 上海优萃生物科技有限公司 | Makeup removing composition and preparation method and application thereof |
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