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CN106264786B - A kind of chest enhancement prosthesis - Google Patents

A kind of chest enhancement prosthesis Download PDF

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Publication number
CN106264786B
CN106264786B CN201610845249.1A CN201610845249A CN106264786B CN 106264786 B CN106264786 B CN 106264786B CN 201610845249 A CN201610845249 A CN 201610845249A CN 106264786 B CN106264786 B CN 106264786B
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CN
China
Prior art keywords
parts
shell body
main leaf
vitellarium
riser
Prior art date
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Expired - Fee Related
Application number
CN201610845249.1A
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Chinese (zh)
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CN106264786A (en
Inventor
郑浩
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Beijing Sheng Jiarong medical beauty hospital limited liability company
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Chengdu Cedisen Biological Technology Co Ltd
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Priority to CN201610845249.1A priority Critical patent/CN106264786B/en
Publication of CN106264786A publication Critical patent/CN106264786A/en
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Publication of CN106264786B publication Critical patent/CN106264786B/en
Expired - Fee Related legal-status Critical Current
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/12Mammary prostheses and implants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/02Inorganic materials
    • A61L27/025Other specific inorganic materials not covered by A61L27/04 - A61L27/12
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14Macromolecular materials
    • A61L27/18Macromolecular materials obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14Macromolecular materials
    • A61L27/20Polysaccharides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14Macromolecular materials
    • A61L27/22Polypeptides or derivatives thereof, e.g. degradation products
    • A61L27/227Other specific proteins or polypeptides not covered by A61L27/222, A61L27/225 or A61L27/24
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/38Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
    • A61L27/3804Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by specific cells or progenitors thereof, e.g. fibroblasts, connective tissue cells, kidney cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/38Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
    • A61L27/3839Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by the site of application in the body
    • A61L27/3873Muscle tissue, e.g. sphincter
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Transplantation (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Dermatology (AREA)
  • Biomedical Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Vascular Medicine (AREA)
  • Botany (AREA)
  • Cell Biology (AREA)
  • Zoology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Inorganic Chemistry (AREA)
  • Cardiology (AREA)
  • Prostheses (AREA)

Abstract

The invention discloses a kind of chest enhancement prosthesis, belongs to face-lifting device field.A kind of chest enhancement prosthesis of the present invention, including shell body, the shell body are hollow cavity, the shell body outline is in human breast shape, and the shell body bottom caves inward, and middle part is provided with vitellarium in the shell body, inside the shell body, vitellarium both sides are provided with fill area.A kind of chest enhancement prosthesis of the invention is each individual with that perfect can adapt to, with excellent handle and form, there is high security simultaneously, rebound performance is good, is unlikely to deform, and histocompatbility is good, tissue can be avoided to reject and attack, reduce the possibility that implant triggers complication, human body is had no toxic side effect, enable to be implanted the characteristics of people obtains body-sensing identical with basic stitch.

Description

A kind of chest enhancement prosthesis
Technical field
The present invention relates to a kind of lift face apparatus, particularly a kind of chest enhancement prosthesis.
Background technology
Prosthese is enlarged the bosom, and material category is more, and classification is different, can be divided into Silica hydrogel packed type and life by its intracapsular tolerant difference Manage salt solution filling type etc.;It can be divided into injection type by its application method and insert type, general Silica hydrogel packed type is to insert type, physiology Salt solution filling type is injection type;In addition, the material such as also superseded atoleine, liquid-state silicon gel, Elipten AG, these Material can cause many severe complications, have toxic side effect, be prohibited use.It is existing to enlarge the bosom material still Using Silica hydrogel and physiological saline as main flow, although biological respinse caused by Silica hydrogel and physiological saline is minimum, compared with other materials more Add softness, naturally, still physiological saline has very strong also body-sensing, easy to leak, the effect of mamaplasty is difficult to maintain, meeting after salt solution oozes out Breast deflating phenomenon is caused, influences profile.It is not good enough with respect to form for silicon gel artificial body and feel, and put for a long time in human body Putting can make the intracapsular portion of salt solution easily produce mould;And the capsule contracture incidence of Silica hydrogel is higher, while there is immunity connective Organize disease and carcinogenic risk, and Silica hydrogel generally using so for many years after, complication gradually shows, it is known that complication master Will be by granuloma, simultaneously as Silica hydrogel is prefabricated implant, shapes and sizes are usually the fixed dimension of standard, can not Perfectly agreed with each individual, and formality complexity is customized according to each individual, it is with high costs;No matter but which kind of Implant, it can not all make it that being implanted human body obtains and basic stitch identical body-sensing.
The content of the invention
The goal of the invention of the present invention is:For above-mentioned problem, there is provided one kind perfect can adapt to each individual, With excellent handle and form, while there is high security, rebound performance is good, is unlikely to deform, and histocompatbility is good, can keep away Exempt from tissue rejection and attack, reduce implant trigger complication possibility, human body is had no toxic side effect, enable to by It is implanted into the chest enhancement prosthesis that people obtains body-sensing identical with basic stitch.
The technical solution adopted by the present invention is as follows:
A kind of chest enhancement prosthesis of the present invention, including shell body, the shell body are hollow cavity, the shell body foreign steamer Exterior feature is in human breast shape, and the shell body bottom caves inward, and middle part is provided with vitellarium, the shell body in the shell body Inside, vitellarium both sides are provided with fill area, the vitellarium of the total volume 65%, and the vitellarium is hollow cavity, the life The cavity rate in long area is 24%, and the cavity of the vitellarium is used to fill autologous adipose tissue.
By adopting the above-described technical solution, outer housing bottom set depressed area, can implant be implanted into human body after, Rest area is provided for original breast tissue, can be avoided after implant is taken out, original breast tissue shape is destroyed, The space that may be grown is provided for intramammary histocyte simultaneously, ensures the free degree that human body organizer has, aforementioned proportion chi It is very little most appropriate, after filling autologous adipose tissue, good organism adaptability can be ensured.
A kind of chest enhancement prosthesis of the present invention, the vitellarium top are provided with connecting at the top of shell body in the vitellarium Some stators and some fibre pipes, the stator surface are evenly equipped with some through holes, and the fibre pipe will be fixed through through hole Piece connects.
By adopting the above-described technical solution, can be capillary, nerve fibre tip by stator and fibre pipe Deng providing growing space, ensure the blood circulation of basic stitch, so as to ensure the connection of basic stitch body and overlaying skin, so as to ensure Implant can still bring original body-sensing.
A kind of chest enhancement prosthesis of the present invention, the stator include main leaf, and the main leaf is vertically located at vitellarium Middle part, the main leaf surface are evenly equipped with three row through holes;The main leaf both sides are provided with two transverse sheets, each described horizontal stroke in the horizontal direction Piece surface is evenly equipped with an exhausting hole;Both sides are provided with two risers below the main leaf, and each described riser surface is evenly equipped with a row Through hole.
By adopting the above-described technical solution, the through hole arranged by different directions can ensure that fibre pipe is staggered, Growth closest to the original capillary of human body, nerve fibre tip is arranged.
A kind of chest enhancement prosthesis of the present invention, the transverse sheet level height are less than the level height on main leaf top, the transverse sheet Level height is more than the level height on riser top;The top of the main leaf and shell body interval, the bottom of the main leaf with it is outer Housing bottom connects, both ends and the vitellarium inwall interval of the transverse sheet, bottom and the shell body bottom connection of the riser, institute Main leaf, transverse sheet and riser is stated to be spaced.
A kind of chest enhancement prosthesis of the present invention, the surface area of the transverse sheet are the 40% of main leaf surface, the surface area of the riser For the 35% of main leaf surface.
A kind of chest enhancement prosthesis of the present invention, the fibre pipe are distributed in the both sides of main leaf, and each described fibre pipe passes through Riser, transverse sheet and/or main leaf connect shell body bottom with top, and the fibre pipe per side has three kinds to pass through mode respectively, wrap Include and sequentially pass through transverse sheet and riser from top to bottom, up to sequentially pass through main leaf, transverse sheet and riser down, and sequentially pass through from top to bottom Main leaf and riser.
A kind of chest enhancement prosthesis of the present invention, the shell body is by 27 parts of polyethers of mass parts, 13 parts of modified silica-gels, 17 parts of octamethylcy-clotetrasiloxanes, 8 parts of methyl methacrylates 55 parts of Silica hydrogels and 3 parts of sodium carboxymethyl starch compositions, the thickness of the shell body is 0.8cm.
By adopting the above-described technical solution, shell body, which using Silica hydrogel as base material, has carried out modification, reduces Silica hydrogel bag Film contracture incidence, adds the rebound performance of shell body, is unlikely to deform, can long term shape retention, it is nontoxic to human body secondary to make With reducing granulomatous occurrence probability.
A kind of chest enhancement prosthesis of the present invention, the fibre pipe is by 6 parts of foam silicon carbons of mass parts, 23 parts of polycaprolactones, and 17 Part PLA, 37 parts of PEKKs, 32 parts of fat stem cell-protein hydrogels and 3 parts of dilute citric acids compositions, it is described to gather in oneself Ester, PLA and PEKK are cross-linked to form porous support, and the porosity of the porous support is 43.8%, and the fat is dry thin In born of the same parents-protein hydrogel, protein hydrogel is Nano chitosan BMP, and the pH of the protein hydrogel is 6.4, described Fat stem cell:Chitosan:Bone morphogenic proteins quality is than 2.3:17.2:6.
By adopting the above-described technical solution, fat stem cell can live for organization survival, it is thin to provide angiogenic growth for growth Born of the same parents, after cell forms stable structure, hydrogel structure is metabolized decomposition, its position being originally present, and just turns into and is available for Blood vessel extends and the cavity of development.
A kind of chest enhancement prosthesis of the present invention, it is described gel filled by mass parts 55 filled with gel filled in the fill area Part agarose, 13 parts of chitosans, 72 parts of Silica hydrogels, 19 parts of N- carboxymethyl chitosans and 7 parts of carboxymethyl celluloses compositions.
By adopting the above-described technical solution, packing material can reduce the risk that Silica hydrogel induces complication, have simultaneously There is good feel, close to tissue, the adaptation that can carry out shape as needed in implantation changes material softness, so as to Reach adapt to each individual demand, gel filled condensation performance is good, when alteration of form occurs, be not in hole, Crack etc..
In summary, by adopting the above-described technical solution, the beneficial effects of the invention are as follows:
1st, each individual perfect can be adapted to, there is excellent handle and form, while there is high security, rebound performance It is good, it is unlikely to deform, histocompatbility is good, and tissue can be avoided to reject and attack, and reduce that implant triggers complication can Energy property, has no toxic side effect to human body, enables to be implanted people's acquisition body-sensing identical with basic stitch.
2nd, reduce the risk that Silica hydrogel induces complication, while there is good feel, material softness close to tissue, The adaptation that shape can be carried out as needed in implantation changes, gel filled so as to reach each individual demand that adapts to Condensation performance it is good, be not in hole, crack etc. when alteration of form occurs.
Brief description of the drawings
Fig. 1 is a kind of chest enhancement prosthesis structural representation.
Marked in figure:1 is shell body, and 2 be vitellarium, and 3 be fill area, and 4 be main leaf, and 5 be transverse sheet, and 6 be riser.
Embodiment
Below in conjunction with the accompanying drawings, the present invention is described in detail.
In order that the object, technical solution and advantage of invention are more clearly understood, below in conjunction with drawings and Examples, to this Invention is further elaborated.It should be appreciated that the specific embodiments described herein are merely illustrative of the present invention, not For limiting the present invention.
Embodiment 1
As shown in figure 1, a kind of chest enhancement prosthesis, including shell body 1, shell body 1 is hollow cavity, the outline of shell body 1 In human breast shape, the bottom of shell body 1 caves inward, and middle part is provided with vitellarium 2 in shell body 1, inside shell body 1, grows The both sides of area 2 are provided with fill area 3, vitellarium 2 of the total volume 65%, and vitellarium is hollow cavity, and the cavity rate of vitellarium is 24%, Vitellarium 2 of the total volume 65%, vitellarium are hollow cavity, and the cavity rate of vitellarium is 24%, and the cavity of vitellarium is used to fill out Fill autologous adipose tissue.The top of vitellarium 2 connects with the top of shell body 1, if being provided with some stators and dry fibers in vitellarium 2 Pipe, stator surface are evenly equipped with some through holes, and fibre pipe connects stator through through hole.Stator includes main leaf 4, main leaf edge For vertical direction located at the middle part of vitellarium 2, the surface of main leaf 4 is evenly equipped with three row through holes;The both sides of main leaf 4 are provided with two transverse sheets in the horizontal direction 5, each described transverse sheet surface is evenly equipped with an exhausting hole;The lower section both sides of main leaf 4 are provided with two risers 6, each described riser table Face is evenly equipped with a row through hole.Transverse sheet level height is less than the level height on main leaf top, and transverse sheet level height is more than riser top Level height;The top of main leaf is spaced with shell body 1, bottom and the bottom connection of shell body 1, the both ends of transverse sheet and the life of main leaf The long inwall interval of area 2, bottom and the bottom connection of shell body 1 of riser, main leaf, transverse sheet and riser are spaced.The surface of transverse sheet Product is the 40% of main leaf surface, and the surface area of riser is the 35% of main leaf surface.Fibre pipe is distributed in the both sides of main leaf, and each is fine Dimension pipe connects the bottom of shell body 1 with top through riser, transverse sheet and/or main leaf, and the fibre pipe per side has three kinds to wear respectively Mode is crossed, including sequentially passes through transverse sheet and riser from top to bottom, up to sequentially passes through main leaf, transverse sheet and riser down, and from up to Under sequentially pass through main leaf and riser.
Shell body 1 is by 27 parts of polyethers of mass parts, 13 parts of modified silica-gels, 17 parts of octamethylcy-clotetrasiloxanes, 8 parts of methyl methacrylates, 55 parts of Silica hydrogels Formed with 3 parts of sodium carboxymethyl starches, the thickness of shell body 1 is 0.8cm.For fibre pipe by 6 parts of foam silicon carbons of mass parts, 23 parts poly- Caprolactone, 17 parts of PLAs, 37 parts of PEKKs, 32 parts of fat stem cell-protein hydrogels and 3 parts of dilute citric acid compositions, gather Caprolactone, PLA and PEKK are cross-linked to form porous support, and the porosity of porous support is 43.8%, fat stem cell-egg In plain boiled water gel, protein hydrogel is Nano chitosan BMP, and the pH of protein hydrogel is 6.4, fat stem cell:Shell Glycan:Bone morphogenic proteins quality is than 2.3:17.2:6.It is gel filled by 55 parts of fine jades of mass parts filled with gel filled in fill area 3 Lipolysaccharide, 13 parts of chitosans, 72 parts of Silica hydrogels, 19 parts of N- carboxymethyl chitosans and 7 parts of carboxymethyl cellulose compositions.
Embodiment 2
PolyethersSynthesize by the following method:
At room temperature to configuration mechanical agitation, reflux condensing tube, thermometer, dropping funel four-hole bottle in add 69.5g (0.2mol)Hexachlorocyclotriph,sphazene and 200mL tetrahydrofurans, after stirring is dissolved after solid whole portion, it is added dropwise dissolved with 69.7g phenol The tetrahydrofuran solution of sodium;After being added dropwise to complete, back flow reaction 3h, filter and collect filtrate;A four-hole bottle separately is taken, is sequentially added 146.5g parahydroxyben-zaldehydes, 300mL tetrahydrofurans and 414.6g Anhydrous potassium carbonates, stir completely molten to parahydroxyben-zaldehyde Xie Hou, the filtrate of above-mentioned gained is added dropwise thereto, is added dropwise to complete rear back flow reaction 6h, is filtered after the completion of reaction, after collecting filtrate It is concentrated into the 1/4 of original volume;Then, remaining mixture is slowly put into frozen water, quick stirring is until faint yellow creamy liquid Body all separates out;Successively with 10% KOH solution, water, methanol detergent cream grease, until all solids separate out;Vacuum after suction filtration Dry to weight, obtain pale yellow powder shape solid.
Embodiment 3
Modified silica-gelSynthesize by the following method:
20g silica gel is added in concentrated hydrochloric acid, 6h is heated to reflux, is washed with deionized to neutrality, 16h is dried at 180 DEG C After obtain activated silica gel.8g activated silica gels are added in the toluene solvant that 80mL is dried, 8mL3- chloropropyls are slowly added dropwise thereto Triethoxysilane, under nitrogen protection, back flow reaction 12h, filtering, product is repeatedly washed with toluene, ethanol and ether successively, 6h is dried in vacuo at 80 DEG C.6g thiosemicarbazides is added in 100mL ethanol, heating makes its dissolving, adds 8g the said goods, backflow 8h is reacted, filtering, is repeatedly washed with ethanol and hot water, is dried in vacuo 12h at 80 DEG C, obtains target product.
Embodiment 4
Fat stem cell-protein hydrogel is prepared by the following method:
BMP is wrapped in Nano chitosan solution first, 2 ~ 4h of sealing and standing, under magnetic stirring, by than Fat stem cell is included in solution by example, and 56% sodium β-glycerophosphate is added dropwise in chitosan solution, and solution is gradually muddy, It is in limpid state to continue to be added dropwise to solution, stops being added dropwise, adds 0.1mmol/L second acid for adjusting pH to 7.2.Filtration sterilization, it is close Envelope, obtains fat stem cell-protein hydrogel.
The foregoing is merely illustrative of the preferred embodiments of the present invention, is not intended to limit the invention, all essences in the present invention All any modification, equivalent and improvement made within refreshing and principle etc., should be included in the scope of the protection.

Claims (7)

  1. A kind of 1. chest enhancement prosthesis, it is characterised in that:Including shell body(1), the shell body(1)It is described outer for hollow cavity Housing(1)Outline is in human breast shape, the shell body(1)Bottom caves inward, the shell body(1)Interior middle part is provided with Vitellarium(2), the shell body(1)Inside, vitellarium(2)Both sides are provided with fill area(3), the vitellarium(2)Account for cumulative volume 65%, the vitellarium is hollow cavity, and the cavity rate of the vitellarium is 24%, the cavity of the vitellarium be used to filling from Body adipose tissue;The vitellarium(2)Top and shell body(1)Top connects, the vitellarium(2)It is interior to be provided with some stators With some fibre pipes, the stator surface is evenly equipped with some through holes, and the fibre pipe connects stator through through hole;It is described Fibre pipe is dry thin by 6 parts of foam silicon carbons of mass parts, 23 parts of polycaprolactones, 17 parts of PLAs, 37 parts of PEKKs, 32 parts of fat Born of the same parents-protein hydrogel and 3 parts of dilute citric acid compositions, the polycaprolactone, PLA and PEKK are cross-linked to form porous support, The porosity of the porous support is 43.8%, and in the fat stem cell-protein hydrogel, protein hydrogel gathers for nanoshell Sugared BMP, the pH of the protein hydrogel is 6.4, the fat stem cell:Chitosan:Bone morphogenic proteins quality ratio 2.3:17.2:6.
  2. A kind of 2. chest enhancement prosthesis as claimed in claim 1, it is characterised in that:The stator includes main leaf(4), the main leaf Vertically it is located at vitellarium(2)Middle part, the main leaf(4)Surface is evenly equipped with three row through holes;The main leaf(4)Both sides Yan Shui Square to provided with two transverse sheets(5), each described transverse sheet surface is evenly equipped with an exhausting hole;The main leaf(4)Lower section both sides are provided with Two risers(6), each described riser surface is evenly equipped with a row through hole.
  3. A kind of 3. chest enhancement prosthesis as claimed in claim 2, it is characterised in that:The transverse sheet level height is less than main leaf top Level height, the transverse sheet level height are more than the level height on riser top;The top of the main leaf and shell body(1)Between Every the bottom of the main leaf and shell body(1)Bottom connection, the both ends and vitellarium of the transverse sheet(2)Inwall interval, it is described perpendicular The bottom of piece and shell body(1)Bottom connection, the main leaf, transverse sheet and riser are spaced.
  4. A kind of 4. chest enhancement prosthesis as claimed in claim 2 or claim 3, it is characterised in that:The surface area of the transverse sheet is main leaf surface 40%, the surface area of the riser is the 35% of main leaf surface.
  5. A kind of 5. chest enhancement prosthesis as claimed in claim 4, it is characterised in that:The fibre pipe is distributed in the both sides of main leaf, often One fibre pipe passes through riser, transverse sheet and/or main leaf by shell body(1)Bottom connects with top, the fibre pipe per side There are three kinds to pass through mode respectively, including sequentially pass through transverse sheet and riser from top to bottom, up to sequentially pass through main leaf down, transverse sheet and perpendicular Piece, and main leaf and riser are sequentially passed through from top to bottom.
  6. A kind of 6. chest enhancement prosthesis as claimed in claim 5, it is characterised in that:The shell body(1)By 27 parts of polyethers of mass parts, 13 parts of modified silica-gels, 17 parts of prestoxs Cyclotetrasiloxane, 8 parts of methyl methacrylates, 55 parts of Silica hydrogels and 3 parts of sodium carboxymethyl starch compositions, the shell body(1)Thickness Spend for 0.8cm.
  7. A kind of 7. chest enhancement prosthesis as claimed in claim 6, it is characterised in that:The fill area(3)It is interior filled with gel filled, institute State gel filled by 55 parts of agaroses of mass parts, 13 parts of chitosans, 72 parts of Silica hydrogels, 19 parts of N- carboxymethyl chitosans and 7 parts of carboxylics Methylcellulose forms.
CN201610845249.1A 2016-09-24 2016-09-24 A kind of chest enhancement prosthesis Expired - Fee Related CN106264786B (en)

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Application Number Priority Date Filing Date Title
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Application Number Priority Date Filing Date Title
CN201610845249.1A CN106264786B (en) 2016-09-24 2016-09-24 A kind of chest enhancement prosthesis

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CN106264786B true CN106264786B (en) 2018-01-26

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109745147B (en) * 2019-02-28 2021-06-29 浙江省肿瘤医院 Method for manufacturing full-autologous tissue double-layer envelope conformable breast prosthesis
CN112022437A (en) * 2019-06-03 2020-12-04 陈建霞 Chest augmentation prosthesis based on five-line inner edge and implantation method thereof

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