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CN105920709B - The Po Nang mechanism of powder spray drug delivery device - Google Patents

The Po Nang mechanism of powder spray drug delivery device Download PDF

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Publication number
CN105920709B
CN105920709B CN201610389658.5A CN201610389658A CN105920709B CN 105920709 B CN105920709 B CN 105920709B CN 201610389658 A CN201610389658 A CN 201610389658A CN 105920709 B CN105920709 B CN 105920709B
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China
Prior art keywords
powder spray
anther sac
medicine storehouse
lancet tip
delivery device
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CN201610389658.5A
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Chinese (zh)
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CN105920709A (en
Inventor
刘金玲
吴磊
周勇
陈志敏
王颖硕
胡锡江
章子毅
王天星
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
ZHEJIANG E-LINKCARE MEDICAL TECHNOLOGY Co.,Ltd.
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Zhejiang Bai'an Medical Technology Co Ltd
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  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)

Abstract

The invention discloses a kind of Po Nang mechanisms of powder spray drug delivery device, medicine storehouse including built-in powder spray anther sac and the pricker through medicine storehouse inner wall, the tip of pricker is towards in medicine storehouse and being located at the position of powder spray anther sac, pricker is located at the other end on the outside of medicine storehouse equipped with key, the medicine storehouse places powder spray anther sac uprightly, the key at least has two pieces of prickers, the upper end that at least one piece of lancet tip is located at powder spray anther sac, the lower end that at least another piece of lancet tip is located at powder spray anther sac, lancet tip positioned at powder spray anther sac upper end is biased relative to the lancet tip for being located at powder spray anther sac upper end.Due to arrangement and the left and right biasing up and down of two pieces of prickers on key of the present invention, powder spray anther sac is upright, so that the powder spray anther sac Emptying Rate 100% of drug treatment, dust cloud mixed gas concentration partial deviations are less than 1%, and the self-consistent property of drug treatment effect is up to 99% or more in the entire course for the treatment of.

Description

The Po Nang mechanism of powder spray drug delivery device
Technical field
The present invention relates to the field of medical instrument technology more particularly to a kind of for treating the powder spray of chronic respiratory disease The drug delivery device of sucking.
Background technique
Respiratory disease is a kind of common disease, and with the deterioration of air quality, the disease incidence of respiratory disease is higher and higher, Especially chronic respiratory disease can bring the higher pain of misery index to patient.Chronic respiratory is treated in Hospitals at Present Main, the most effective way of tract disease have metered dose inhalation aerosol, Foradil Aerolizer formoterol fumarate, atomized inhalation, Foradil Aerolizer formoterol fumarate It is called powder spray, the administration apparatus of powder spray is powder spray drug delivery device.
In the prior art as the notification number of Granted publication on the 28th in Patent Office of the People's Republic of China's November in 2007 is CN 200980876Y Utility model patent, a kind of dust cloud inhaler described in the patent, it is that both ends respectively have a root thorn capsule pricker and help equipped with air-flow The capsule type inhalation aerosol powder drug delivery device of power device is made of box cover, mouth haustorium, chassis and air-flow booster, two root thorn needles point It is not fixed in the key of chassis two sides, blister cavities and air-flow aperture constitute the air-flow booster connecting with chassis, and blister cavities is by having The pliable material of elasticity is made.These dust cloud inhalers be essentially all powder spray anther sac is horizontal, respectively pierced at the both ends of anther sac A medicine outlet hole out is rotated anther sac by air-flow booster, using anther sac rotation generate centrifugal force by powder spray from Medicine outlet hole throws away to realize administration, since the medicine outlet hole of anther sac is located at the endpoint at anther sac both ends, the dust cloud of anther sac lower half portion Agent is difficult to throw away completely under gravity, is also difficult to reach drug uniform purpose during throwing away, to can give Administering effect brings adverse effect.
Summary of the invention
In order to overcome drawbacks described above, the present invention is intended to provide a kind of Po Nang mechanism of powder spray drug delivery device, makes powder spray The medicine outlet hole reasonable Arrangement of anther sac, drug are in the right direction, to ensure that powder spray anther sac drug completely, uniformly, reaches for patient Best therapeutic effect offer is effectively ensured.
The present invention solves prior art technical solution of problems: a kind of Po Nang mechanism of powder spray drug delivery device, Medicine storehouse including built-in powder spray anther sac and the pricker through medicine storehouse inner wall, the tip of pricker is towards in medicine storehouse and being located at powder spray At the position of anther sac, pricker is located at the other end on the outside of medicine storehouse equipped with key, and the medicine storehouse places powder spray anther sac uprightly, institute Stating key at least has two pieces of prickers, the upper end that at least one piece of lancet tip is located at powder spray anther sac, and at least another piece Lancet tip is located at the lower end of powder spray anther sac, and the lancet tip positioned at powder spray anther sac upper end is relative to positioned at powder spray The lancet tip of anther sac lower end is to the left or right side biases.The shape of powder spray anther sac is general intermediate cylindrical, and both ends are in Spherical crown shape uprightly places powder spray anther sac, does not pierce out through-hole in the upper and lower spherical cap portion of powder spray anther sac, upper through-hole is mainly used In air inlet, lower through-hole is mainly used for drug, and such powder spray anther sac is rotated in the case where the wind-force of air inlet drives, and powder spray is in gravity It is thrown away under effect from lower through-hole, since air is replenished in time in upper through-hole, negative pressure will not be generated in powder spray anther sac, so that powder spray It can uniformly, fully be administered.Due to being located at the lancet tip of powder spray anther sac upper end relative on powder spray anther sac The lancet tip of end is to the left or right side biasing, it is preferable that the lancet tip in spherical crown portion and is located on powder spray anther sac The lancet tip in spherical crown portion is arranged on powder spray anther sac central axis under powder spray anther sac and the central axis of key up and down direction is common The plane two sides of formation, and be located at powder spray anther sac on spherical crown portion pricker and the pricker in spherical crown portion is equal under powder spray anther sac It is tangent with spherical crown portion inner wall, in this way, the air entered from upper through-hole can form spiral shape whirlwind, punching along powder spray anther sac inner wall The powder spray being adhered on powder spray anther sac inner wall is hit, so that it is fallen off, it is ensured that powder spray is administered completely.
Preferably, the number of keys is two, two keys are located at the opposite two sides in medicine storehouse.It is operating in this way When key, the active force positioned at two keys of medicine storehouse opposite sides can liquidate, and convenient for patients uses.
Preferably, the pricker configuration mode of described two keys is consistent.In this way, not only there is good interchangeability, and And the type of accessory can be reduced, reduce manufacturing cost, ease of assembly.It can make the upper lower through-hole of powder spray anther sac can be with simultaneously It is axially symmetric relative to powder spray anther sac, be conducive to the uniformity of administration.
Preferably, being equipped with the cavity to match with powder spray anther sac upright state in the medicine storehouse.It may insure powder in this way Mist agent anther sac is kept upright state when rotated.
Preferably, the cavity inner wall is equipped with the air inlet of perforation, the side of air inlet inner wall axial direction and cavity Inner wall is tangent.In this way, the air entered from air inlet can form spiral shape whirlwind along cavity inner wall, and then push powder spray medicine Capsule quickly rotates, and quickly rotates the centrifugal force of generation for the powder spray in powder spray anther sac from powder spray medicine using powder spray anther sac The lower through-hole of capsule is thrown away, while the powder spray thrown away can be broken up by whirlwind again and form uniform mixed gas with air, favorably In the drug treatment effect of patient.
Preferably, be circumferentially with multiple through holes on the inner wall in the medicine storehouse, multiple through holes be located at powder spray medicine The lancet tip of capsule upper end is in same plane.Multiple through holes on the inner wall of medicine storehouse rotate a circle in dust cloud agent capsules can be with Wind is repeatedly given to upper through-hole, generates multiple fitful wind formula whirlwind in powder spray anther sac inner wall, it is ensured that powder spray is administered completely.
Compared with prior art, the invention has the following advantages:
Due to arrangement and the left and right biasing up and down of two pieces of prickers on key of the present invention, powder spray anther sac is upright, so that dust cloud Agent anther sac pierce out two on through-hole, two lower through-holes be respectively symmetrically located at the upper and lower spherical crown portion of powder spray anther sac, and upper vent hole can be with Fitful wind formula spiral shape whirlwind is repeatedly generated in powder spray anther sac, so that the powder spray anther sac Emptying Rate of drug treatment 100%, dust cloud mixed gas concentration partial deviations are less than 1%, and the self-consistent property of drug treatment effect is up to 99% in the entire course for the treatment of More than.
Detailed description of the invention
Fig. 1 is a kind of structural upright schematic diagram of powder spray drug delivery device;
Fig. 2 is a kind of structural blast schematic diagram of powder spray drug delivery device;
Fig. 3 is the echelon sectional view in Chinese medicine storehouse of the present invention;
Fig. 4 is the stereoscopic schematic diagram of key in the present invention;
Fig. 5 is the schematic front view of key in the present invention;
Fig. 6 is A-A schematic cross-sectional view in Fig. 3;
Fig. 7 is B-B schematic cross-sectional view in Fig. 3;
Fig. 8 is C-C schematic cross-sectional view in Fig. 3.
In figure: suction nozzle 1, pedestal 2, key 3, spring 4, medicine storehouse 5, through hole 6, pricker 7, air inlet 8, pricker hole 9, powder Mist agent anther sac 10, upper through-hole 11, lower through-hole 12.
Specific embodiment
Below by specific embodiment, and in conjunction with attached drawing, the technical solution of invention is described in further detail:
Embodiment: a kind of Po Nang mechanism of powder spray drug delivery device, as shown in Figure 1 and Figure 2, including suction nozzle 1, medicine storehouse 5, bullet Spring 4, key 3, pedestal 2, as shown in figure 3, the cavity to match with 10 upright state of powder spray anther sac is equipped in medicine storehouse 5, in cavity Powder spray anther sac 10 is placed, the upper/lower terminal of powder spray anther sac 10 is in spherical crown shape, and the centre of powder spray anther sac 10 is cylindrical, As shown in Figure 2, Figure 3, Figure 4, it is provided with the pricker hole 9 of perforation on 5 inner wall of medicine storehouse, is arranged on the key 3 of 5 two opposite outer of medicine storehouse Two pieces of prickers 7 are equipped with, pricker 7 runs through 5 cavity inner wall of medicine storehouse by pricker hole 9, wherein the tip of one piece of pricker 7 is directed at dust cloud At the upper spherical crown of agent anther sac 10, at the lower spherical crown of the tip alignment powder spray anther sac 10 of another piece of pricker 7, in this way, in powder spray The upper and lower spherical crown portion of anther sac 10 can pierce out through-hole 11, lower through-hole 12 respectively, as shown in figs. 3 and 5, be located at powder spray anther sac 10 Pricker 7 at upper spherical crown and the pricker 7 at the lower spherical crown of powder spray anther sac 10 are arranged on the symmetrical of 3 up and down direction of key extension The two sides of axis, and it is equidistant with the symmetry axis, 7 configuration mode of pricker of two keys 3 is consistent, as shown in Fig. 3, Fig. 6, medicine storehouse 5 Multiple through holes 6 are circumferentially evenly equipped on inner wall, multiple through holes 6 and the upper through-hole 11 in spherical crown portion on powder spray anther sac 10 are in together The inner wall of one plane, upper through-hole 11 and upper spherical crown is tangent, and as shown in Fig. 3, Fig. 7, the opposite two sides of the cavity inner wall are set respectively There is the air inlet 8 of perforation, the side of air inlet 8 inner wall axial direction and the inner wall of cavity are tangent, as shown in Fig. 3, Fig. 8, lower through-hole 12 It is tangent with the inner wall of lower spherical crown.
Powder spray drug delivery device of the invention passes through experimental verification, the result of detection are as follows: the powder spray anther sac of drug treatment Emptying Rate 100%, dust cloud mixed gas concentration partial deviations are less than 1%, the self-consistent property of drug treatment effect in the entire course for the treatment of Up to 99% or more.
Embodiment described above is a kind of preferred version of the invention, not does limit in any form to the present invention System, there are also other variations and modifications on the premise of not exceeding the technical scheme recorded in the claims.
The content being not described in detail in this specification belongs to the prior art well known to those skilled in the art.

Claims (4)

1. a kind of Po Nang mechanism of powder spray drug delivery device, the medicine storehouse including built-in powder spray anther sac and the thorn through medicine storehouse inner wall Needle, towards in medicine storehouse and being located at the position of powder spray anther sac, the other end that pricker is located on the outside of medicine storehouse is equipped with for the tip of pricker Key, it is characterised in that: the medicine storehouse places powder spray anther sac uprightly, and the key at least has two pieces of prickers, at least One piece of lancet tip is located at the upper spherical crown portion of powder spray anther sac, the lower ball that at least another piece of lancet tip is located at powder spray anther sac Bizet, positioned at spherical crown portion on powder spray anther sac lancet tip relative to be located at powder spray anther sac under spherical crown portion lancet tip to Left or right side biasing;It is equipped with the cavity to match with powder spray anther sac upright state in the medicine storehouse, is set on the cavity inner wall There is the air inlet of perforation, the side of air inlet inner wall axial direction and the inner wall of cavity are tangent, and the air inlet is located at upper and lower spherical crown portion Between.
2. the Po Nang mechanism of powder spray drug delivery device according to claim 1, it is characterised in that: the number of keys is two A, two keys are located at the opposite two sides in medicine storehouse.
3. the Po Nang mechanism of powder spray drug delivery device according to claim 2, it is characterised in that: the thorn of described two keys Needle configuration mode is consistent.
4. the Po Nang mechanism of powder spray drug delivery device according to any one of claims 1 to 3, it is characterised in that: the medicine storehouse Inner wall on be circumferentially with multiple through holes, the lancet tip in multiple through holes and the spherical crown portion on powder spray anther sac that is located at is in same One plane.
CN201610389658.5A 2016-06-06 2016-06-06 The Po Nang mechanism of powder spray drug delivery device Active CN105920709B (en)

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CN201610389658.5A CN105920709B (en) 2016-06-06 2016-06-06 The Po Nang mechanism of powder spray drug delivery device

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Application Number Priority Date Filing Date Title
CN201610389658.5A CN105920709B (en) 2016-06-06 2016-06-06 The Po Nang mechanism of powder spray drug delivery device

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CN105920709B true CN105920709B (en) 2019-05-21

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109821118A (en) 2017-11-23 2019-05-31 正大天晴药业集团股份有限公司 Novel lung delivery system
CN114534032B (en) * 2021-04-16 2023-06-06 浙江萃泽医药科技有限公司 Dry powder inhalation device and method of operating a dry powder inhalation device
CN115814217B (en) * 2023-02-14 2023-05-12 杭州希溪制药有限公司 Powder aerosol inhalation device

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN2753402Y (en) * 2004-12-17 2006-01-25 上海医药工业研究院 Capsule dry-powder inhaling device
CN2933442Y (en) * 2006-07-28 2007-08-15 李国华 Double-air-passage inhalation device for medicament powder inhaler
CN200960345Y (en) * 2006-10-17 2007-10-17 温明春 Spring-inserting needle type dry powder inhalation device
CN205849935U (en) * 2016-06-06 2017-01-04 浙江亿联健医疗器械有限公司 The Po Nang mechanism of powder spray doser

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Effective date of registration: 20190423

Address after: 317300 Tongjiang Road, Baita District, Xianju County Economic Development Zone, Taizhou City, Zhejiang Province

Applicant after: Zhejiang Bai'an Medical Technology Co Ltd

Address before: 317300 Room 402, Unit 1, 2 Buildings, Tianli International Hall, Chengguan, Xianju County, Taizhou City, Zhejiang Province

Applicant before: Wang Tianxing

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Effective date of registration: 20201019

Address after: 317300 industrial cluster area of Baita Town Xianju County Taizhou city Zhejiang Province

Patentee after: ZHEJIANG E-LINKCARE MEDICAL TECHNOLOGY Co.,Ltd.

Address before: Baita block Tong Jiang Road Economic Development Zone in Xianju County of Taizhou City, Zhejiang Province, No. 30 317300

Patentee before: ZHEJIANG BAIAN MEDICAL TECHNOLOGY Co.,Ltd.

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