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CN105892317A - Implantable medical device, data outputting and receiving methods thereof and communication mechanism - Google Patents

Implantable medical device, data outputting and receiving methods thereof and communication mechanism Download PDF

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Publication number
CN105892317A
CN105892317A CN201610200540.3A CN201610200540A CN105892317A CN 105892317 A CN105892317 A CN 105892317A CN 201610200540 A CN201610200540 A CN 201610200540A CN 105892317 A CN105892317 A CN 105892317A
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CN
China
Prior art keywords
implantable medical
module
medical device
signal
control module
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Pending
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CN201610200540.3A
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Chinese (zh)
Inventor
姚建江
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Microport Sorin CRM Shanghai Co Ltd
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Microport Sorin CRM Shanghai Co Ltd
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Priority to CN201610200540.3A priority Critical patent/CN105892317A/en
Publication of CN105892317A publication Critical patent/CN105892317A/en
Pending legal-status Critical Current

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    • GPHYSICS
    • G05CONTROLLING; REGULATING
    • G05BCONTROL OR REGULATING SYSTEMS IN GENERAL; FUNCTIONAL ELEMENTS OF SUCH SYSTEMS; MONITORING OR TESTING ARRANGEMENTS FOR SUCH SYSTEMS OR ELEMENTS
    • G05B19/00Programme-control systems
    • G05B19/02Programme-control systems electric
    • G05B19/04Programme control other than numerical control, i.e. in sequence controllers or logic controllers

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  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Engineering & Computer Science (AREA)
  • Automation & Control Theory (AREA)
  • Electrotherapy Devices (AREA)
  • Prostheses (AREA)

Abstract

The invention provides an implantable medical device comprising a control module and a communication module. After the control module receives a complete wave-up signal, the communication module is woken up so as to enable the implantable medical device to receive external data. In an internal data outputting process, the control module controls a pulse generation unit to generate pulse signals, a demodulation circuit is utilize to demodulate the pulse signals into demodulated signals, and the demodulated signals are transmitted to the control module, so that the demodulated signals are utilized to generate a data sending time sequence for internal data outputting. The invention further provides data outputting and receiving methods of the implantable medical device and a communication mechanism. A wireless communication interface, a receiving end and a sending end of the implantable medical device are effectively processed, the wireless communication power consumption of the implantable medical device is substantially lowered, micro-power consumption of the communication module is realized, and the average current of communication is lower than 10[mu]A. The power consumption of the implantable medical device in the communication process is lowered, and the service lifetime of a cell of the implantable medical device is also prolonged.

Description

Implantable medical device and data thereof export and method of reseptance and communication mechanism
Technical field
The present invention relates to field of medical device, particularly relate to a kind of implantable medical device and data output thereof and Method of reseptance and communication mechanism.
Background technology
Programme-control (being called for short program control: programmability) is indivisible one of implantable medical device Function, in today worldwide, major part implantable medical device all possesses programmable function, and along with planting Entering developing rapidly of engineering, the programmable function of implantable medical device gets more and more, and becomes increasingly complex.Just Utilization parameter to benefit can make implantable medical device play its greatest benefit, and patient obtains greatest treatment efficacy.
Implantable medical device system is typically made up of implantable medical device and vitro program controlled device two parts.And Data exchange between implantable medical device and vitro program controlled device is a kind of two-way wireless data transmission, body On the one hand outer program controller needs to be sent to program control command implantable medical device, receives the most again and plants Enter feedback information and measurement diagnostic message that formula armarium sends.
As it is shown in figure 1, the main funtion part of the implantable medical device program control device that currently uses includes: Implantable medical device 1 and vitro program controlled device 2.Implantable medical device 1 is being implanted after human body, journey to be passed through Control device carries out regular follow-up to patient, understands the working condition of implantable medical device 1.When following up a case by regular visits to, Implantable medical device 1 program control device is entered by vitro program controlled device 2 and the implantable medical device implanting human body Row bidirectional data communication.
Generally, the program control command data that vitro program controlled device 2 sends to implantable medical device are less, The highest to transmission rate request;And the data volume that implantable medical device 1 sends to vitro program controlled device 2 is relatively big, And require to must assure that data are reliable with in real time.Therefore, to implantable medical device 1 to vitro program controlled device 2 The design sending data method is the most critically important.
In the patent application of Application No. 201410423172.X, implantable medical device is to vitro program controlled device Sending data method is to open when doctor needs program control to intercept module so that implantable medical device and external Control device and carry out proper communication.But it is the most always on that the defect of this scheme is to intercept module, may lead Cause the loss of data.
Summary of the invention
In order to reduce the communication power consumption of implantable medical device, the present invention provides a kind of implantable medical device, Including control module and the communication module of the described control module of connection, when described control module receives complete After wake-up signal, wake up described communication module up, so that described implantable medical device receives external data.
Optionally, described implantable medical device also includes the module of intercepting connecting described control module, uses In wake-up signal described in perception.
Optionally, intercept module described in wake up up described in perception by the way of detecting described wake-up signal rising edge Signal.
Optionally, described implantable medical device also includes the synchronization signal detection connecting described control module Module, for detecting the integrity of described wake-up signal.
Optionally, described implantable medical device also includes the correction verification module connecting described control module, uses In described wake-up signal is carried out error checking and correction.
Optionally, described correction verification module is by receiving password, and described password carries out the mode of CRC check Described wake-up signal is carried out error checking and correction.
Optionally, described implantable medical device also includes impulse generating unit and demodulator circuit, described arteries and veins Rush generation unit and demodulator circuit and constitute loop with described control module;
Described control module is used for controlling described impulse generating unit and produces pulse signal, and described demodulator circuit is used Being demodulated signal in demodulating described pulse signal and pass to described control module, described control module is according to described Demodulated signal generates data transmission timing, and sets according to the described data transmission timing described implantable medical of control Standby output internal data.
Optionally, described implantable medical device also includes switch element, be connected to described control module and Between described impulse generating unit, described control module controls described pulses generation list by described switch element Unit produces pulse.
Optionally, described impulse generating unit is resonance circuit.
Optionally, described control module is PLD/controller.
The present invention also provides for a kind of data receiver method of above-mentioned implantable medical device, including
Thering is provided implantable medical device, described implantable medical device includes control module and connects described control The communication module of module;And
After described control module receives complete wake-up signal, wake up described communication module up so that described in plant Enter formula armarium and receive external data;If described control module does not receives complete wake-up signal, institute State communication module to remain stationary.
Optionally, after intercepting wake-up signal described in module perception, transmit described wake-up signal to described control mould Block receives for described control module;Maintain when not perceiving wake-up signal and intercept state.
Optionally, intercept module described in wake up up described in perception by the way of detecting described wake-up signal rising edge Signal.
Optionally, after the detection of synchronization signal detection module confirms the integrity of described wake-up signal, wake up up described Communication module.
Optionally, after the detection of described synchronization signal detection module confirms the integrity of described wake-up signal, open Correction verification module carries out error checking and correction to described wake-up signal, if error checking and correction passes through, then wakes up described communication mould up Block;If error checking and correction does not passes through, then intercept module maintenance and intercept state.
Optionally, described correction verification module is by receiving password, and described password carries out the mode of CRC check Described wake-up signal is carried out error checking and correction.
Optionally, also include the communication check module connecting described control module, be used for detecting described implanted Armarium receives whether external data interrupts, and when interrupting more than the setting time, closes and intercepts described in removing Other modules beyond module.
The present invention also provides for the data output method of a kind of above-mentioned implantable medical device, including:
Impulse generating unit and demodulator circuit, described impulse generating unit and demodulator circuit and described control are provided Module composition loop;
Described control module controls described impulse generating unit and produces pulse signal;
Described demodulator circuit demodulates described pulse signal and is demodulated signal and passes to described control module;And
Described control module generates data transmission timing according to described demodulated signal, and sends according to described data Implantable medical device output internal data described in sequencing contro.
Optionally, described control module is by being connected between described control module and described impulse generating unit Switch element control described impulse generating unit produce pulse.
Optionally, described impulse generating unit is resonance circuit.
Optionally, described control module is PLD/controller.
The present invention also provides for the communication mechanism of a kind of implantable medical device, when control module receives complete Communication module is waken up up, so that described implantable medical device receives external data after wake-up signal.
The present invention provides a kind of implantable medical device, including control module with connect the logical of described control module Letter module, wakes up described communication module after control module receives complete wake-up signal again up, so that implanting Formula armarium receives external data.In output internal data, control module is used to control pulses generation list Unit produces pulse signal, and is demodulated signal with demodulator circuit demodulation pulse signal and passes to described control module, Thus utilize demodulated signal to generate data transmission timing to export internal data.The present invention also provides for a kind of implantation The data output of formula armarium and method of reseptance and communication mechanism, by wireless to implantable medical device Effective process of communication interface, receiving terminal and transmission, greatly reduces the radio communication of implantable medical device Power consumption so that communication module reaches Micro Energy Lose, the average current of communication is less than 10uA.Reduce implantable medical While equipment power consumption in the communications, improve the battery of implantable medical device.
Accompanying drawing explanation
Fig. 1 is the funtion part schematic diagram that existing implantable medical device program control device is main;
Fig. 2 is the structural representation of implantable medical device described in one embodiment of the invention;
Fig. 3 is that implantable medical device described in one embodiment of the invention passively wakes up up and receives the stream of external data Cheng Tu;
Fig. 4 is the structural representation of implantable medical device data output unit described in one embodiment of the invention.
Detailed description of the invention
Implantable medical device is typically all and uses battery to power, owing to the existing energy content of battery is limited, to implantation The power consumption requirements of formula armarium is the highest.So necessarily requiring each functional module of implantable medical device It is all low-power consumption or Micro Energy Lose module.In order to more preferably realize energy between implantable medical device and vitro program controlled device Enough stable, reliable, safe transmission, the present invention is while ensureing reliable data transmission, it is ensured that plurality Output according to amount.
Below in conjunction with the drawings and specific embodiments, the present invention is described in further detail.According to following explanation and Claims, advantages and features of the invention will be apparent from.It should be noted that, accompanying drawing all uses the simplest The form changed and all use non-ratio accurately, only in order to convenient, aid in illustrating the embodiment of the present invention lucidly Purpose.
The present invention provides a kind of implantable medical device, as in figure 2 it is shown, include control module 6 and connect institute State the communication module 40 of control module, after described control module 6 receives complete wake-up signal, wake up up Described communication module 40, so that described implantable medical device receives external data.
In the present embodiment, what described implantable medical device also included connecting described control module intercepts mould Block 10, for wake-up signal described in perception.In preferred version, described in intercept module 10 by detection described in call out Wake-up signal described in the mode perception of awake signal rising edge.Described implantable medical device also includes connecting institute State the synchronization signal detection module 20 of control module 6, for detecting the integrity of described wake-up signal.Also wrap Include the correction verification module 30 connecting described control module 6, for described wake-up signal is carried out error checking and correction.Can To be understood by, described correction verification module 30 being carried out to the mode verified, the present invention is not restricted, such as Can be correction verification module 30 by receiving password, and described password be carried out the mode of CRC check to described Wake-up signal carries out error checking and correction.
Understanding based on features described above, described implantable medical device uses and passively wakes up up outside mode of operation reception Portion's data.In this working method, implantable medical device is constantly under wait wake-up signal mode of operation. When can make the wake-up condition that equipment works when there being outer signals to reach, equipment is just started working, the most always In a dormant state.
Specifically, the principle of above-mentioned passive wake module is as it is shown on figure 3, include:
1. intercept after module 10 detects wake-up signal rising edge when implantable medical device, triggering is synchronized Signal detection module 20 (synchronization of for example, FPGA communication ends), if signal detection module 20 detects one Individual complete sync (synchronization) width, then trigger the correction verification module 30 of implantable medical device communication receiver Open error checking and correction.(the most above-mentioned correction verification module 30 of concrete grammar by receiving password, and to described Password carries out CRC check).Without complete sync (synchronization) width being detected, then implant Formula armarium returns initial conditions, only intercepts module 10 in running order, and other module is all in pass Closed state.
2., in order to strengthen the safety of communication system, wake-up signal detects by rear, and communication module 40 enters close Code receives link.Password Length for example, 32bit data, it is by after CRC check, and implantable medical sets There is program control request command for being considered the outside program controller of a complete identification, start implantable medical device Communication module 40, enters formal programmed communication state to receive external data.
3., when communication interruption time is more than the setting time, implantable medical device communication module 40 returns Initial equilibrium state, only intercepts module 10 in running order, and other module is all in closed mode, to reach to subtract The effect of low power consumption.
Implantable medical device of the present invention is except including that above-mentioned employing wireless awakening mode receives external number According to feature outside, also include for interior data output low power dissipation design.
Please continue to refer to Fig. 1, described implantable medical device also includes impulse generating unit 3 and demodulator circuit 5, described impulse generating unit 3 and demodulator circuit 5 constitute loop with described control module 6.Wherein, described Control module 6 is used for controlling described impulse generating unit 3 and produces pulse signal, and described demodulator circuit 5 is used for Demodulating described pulse signal to be demodulated signal and pass to described control module 6, described control module 6 is according to described Demodulated signal generates data transmission timing, and sets according to the described data transmission timing described implantable medical of control Standby output internal data.
Described implantable medical device also includes switch element 4, is connected to described control module 6 and described pulse Between generation unit 3, described control module 6 controls described impulse generating unit 3 by described switch element 4 Produce pulse.
In the present embodiment, as shown in Figure 4, impulse generating unit 3 is private radio communication loop feature, Being made up of LC resonance circuit, generation and the signal of being responsible for RF signal receive.Switch element 4 is N-channel gold Belong to oxide semiconductor field effect pipe (MOSFET), be responsible for sending, receiving the switching of circuit, control module 6 is PLD, can be specifically FPGA, can directly control switch element 4, reach RF defeated Go out the generation of (sequential) Burst.Demodulator circuit 5 is responsible for the burst signal received to be converted to control module 6 (FPGA) discernible digital signal.FPGA is the core control part of RF communication, generates and sends number According to sequential, and to receive modulation-demodulation signal analyze.
The data output unit of implantable medical device, i.e. impulse generating unit 3 and demodulator circuit 5 are with described The specific works flow process that control module 6 constitutes loop is as follows:
1) transmitting terminal of implantable medical device communication uses conducting and the pass of Digital Circuit Control MOSFET Close, thus utilize the vibration of LC resonant tank to produce Burst, FPGA only need to be used to turn on MOSFET, just Can export by communication protocol sequential.
FPGA controls conducting MOSFET pipe, allows electric capacity charge, and is then shut off MOSFET pipe.The most permissible LC resonant tank is allowed to produce fixing Burst as follows.
Implantable medical device uses LC antiresonant circuit, and it is as follows that its resonant frequency calculates formula:
f 0 = 1 2 π 1 L C - ( 2 L R ) 2 - - - [ 1 - 1 ]
Due toSo formula [1-1] may be approximately equal to formula [1-2].
f 0 = 1 2 π L C - - - [ 1 - 2 ]
Owing to the conducting resistance of electric capacity ESR and MOSFET is the least, it is fully charged that electric capacity is almost moment.Implant Formula medical device communication transmitting terminal electric current may be approximately equal to 0.
In conjunction with above-mentioned implantable medical device communication system, the present invention also provides for a kind of implantable medical device Communication system, including above-mentioned implantable medical device and program controller, it is external that described program controller is positioned at patient, uses In sending external data extremely described implantable medical device, and receive the inside number of described implantable medical device According to.
The present invention also provides for a kind of data receiver method of implantable medical device, including:
Thering is provided implantable medical device, described implantable medical device includes control module and connects described control The communication module of module;And
After described control module receives complete wake-up signal, wake up described communication module up so that described in plant Enter formula armarium and receive external data.
The present invention also provides for the data output method of a kind of implantable medical device, including:
Impulse generating unit and demodulator circuit, described impulse generating unit and demodulator circuit and described control are provided Module composition loop;
Described control module controls described impulse generating unit and produces pulse signal;
Described demodulator circuit demodulates described pulse signal and is demodulated signal and passes to described control module;And
Described control module generates data transmission timing according to described demodulated signal, and sends according to described data Implantable medical device output internal data described in sequencing contro.
The data receiver method of the implantable medical device of the present invention and data output intent, above-mentioned to implantation The description of formula armarium is described in detail, therefore here is omitted.
The present invention provides a kind of implantable medical device, including control module with connect the logical of described control module Letter module, wakes up described communication module after control module receives complete wake-up signal again up, so that implanting Formula armarium receives external data.In output internal data, control module is used to control pulses generation list Unit produces pulse signal, and is demodulated signal with demodulator circuit demodulation pulse signal and passes to described control module, Thus utilize demodulated signal to generate data transmission timing to export internal data.The present invention also provides for a kind of implantation The data output of formula armarium and method of reseptance and communication mechanism, by wireless to implantable medical device Effective process of communication interface, receiving terminal and transmission, greatly reduces the radio communication of implantable medical device Power consumption so that communication module reaches Micro Energy Lose, the average current of communication is less than 10uA.Reduce implantable medical While equipment power consumption in the communications, improve the battery of implantable medical device.
Obviously, those skilled in the art can carry out various change and modification without deviating from the present invention to invention Spirit and scope.So, if the present invention these amendment and modification belong to the claims in the present invention and Within the scope of equivalent technologies, then the present invention is also intended to change and including modification include these.

Claims (22)

1. an implantable medical device, it is characterised in that include control module and connect described control module Communication module, after described control module receives complete wake-up signal, wake up described communication module up, So that described implantable medical device receives external data.
2. implantable medical device as claimed in claim 1, it is characterised in that also include connecting described control Molding block intercept module, for wake-up signal described in perception.
3. implantable medical device as claimed in claim 2, it is characterised in that described in intercept module and pass through Detect wake-up signal described in the mode perception of described wake-up signal rising edge.
4. implantable medical device as claimed in claim 1, it is characterised in that also include connecting described control The synchronization signal detection module of molding block, for detecting the integrity of described wake-up signal.
5. implantable medical device as claimed in claim 1, it is characterised in that also include connecting described control The correction verification module of molding block, for carrying out error checking and correction to described wake-up signal.
6. implantable medical device as claimed in claim 5, it is characterised in that described correction verification module passes through Receive password, and the mode that described password carries out CRC check carries out error checking and correction to described wake-up signal.
7. implantable medical device as claimed in claim 1, it is characterised in that also include pulses generation list Unit and demodulator circuit, described impulse generating unit and demodulator circuit constitute loop with described control module;
Described control module is used for controlling described impulse generating unit and produces pulse signal, and described demodulator circuit is used Being demodulated signal in demodulating described pulse signal and pass to described control module, described control module is according to described Demodulated signal generates data transmission timing, and sets according to the described data transmission timing described implantable medical of control Standby output internal data.
8. implantable medical device as claimed in claim 7, it is characterised in that also include switch element, Being connected between described control module and described impulse generating unit, described control module is by described switch unit Part controls described impulse generating unit and produces pulse.
9. implantable medical device as claimed in claim 7, it is characterised in that described impulse generating unit For resonance circuit.
10. implantable medical device as claimed in claim 1, it is characterised in that described control module is PLD/controller.
The data receiver of 11. 1 kinds of implantable medical devices as described in claim 1-10 any one Method, it is characterised in that include
Thering is provided implantable medical device, described implantable medical device includes control module and connects described control The communication module of module;And
After described control module receives complete wake-up signal, wake up described communication module up so that described in plant Enter formula armarium and receive external data;If described control module does not receives complete wake-up signal, institute State communication module to remain stationary.
The data receiver method of 12. implantable medical devices as claimed in claim 11, it is characterised in that After intercepting wake-up signal described in module perception, transmit described wake-up signal to described control module for described control Molding block receives;Maintain when not perceiving wake-up signal and intercept state.
The data receiver method of 13. implantable medical devices as claimed in claim 12, it is characterised in that Described module of intercepting is by detecting wake-up signal described in perception by the way of described wake-up signal rising edge.
The data receiver method of 14. implantable medical devices as claimed in claim 12, it is characterised in that After the detection of synchronization signal detection module confirms the integrity of described wake-up signal, wake up described communication module up.
The data receiver method of 15. implantable medical devices as claimed in claim 14, it is characterised in that After the detection of described synchronization signal detection module confirms the integrity of described wake-up signal, open correction verification module to institute State wake-up signal and carry out error checking and correction, if error checking and correction passes through, then wake up described communication module up;If mistake school Test and do not pass through, then intercept module maintenance and intercept state.
The data receiver method of 16. implantable medical devices as claimed in claim 15, it is characterised in that Described correction verification module is by receiving password, and the mode that described password carries out CRC check wakes up letter up to described Number carry out error checking and correction.
The data receiver method of 17. implantable medical devices as claimed in claim 15, it is characterised in that Also include the communication check module connecting described control module, be used for detecting described implantable medical device and receive Whether external data interrupts, when interrupt more than the setting time time, close except described in intercept module in addition to its His module.
The data output side of 18. 1 kinds of implantable medical devices as described in claim 7-10 any one Method, it is characterised in that including:
Impulse generating unit and demodulator circuit, described impulse generating unit and demodulator circuit and described control are provided Module composition loop;
Described control module controls described impulse generating unit and produces pulse signal;
Described demodulator circuit demodulates described pulse signal and is demodulated signal and passes to described control module;And
Described control module generates data transmission timing according to described demodulated signal, and sends according to described data Implantable medical device output internal data described in sequencing contro.
The data output method of 19. implantable medical devices as claimed in claim 18, it is characterised in that Described control module is by the switch element control being connected between described control module and described impulse generating unit Make described impulse generating unit and produce pulse.
20. implantable medical devices as claimed in claim 18, it is characterised in that described pulses generation Unit is resonance circuit.
21. implantable medical devices as claimed in claim 18, it is characterised in that described control module For PLD/controller.
The communication mechanism of 22. 1 kinds of implantable medical devices, it is characterised in that when control module has received Communication module is waken up up, so that described implantable medical device receives external data after whole wake-up signal.
CN201610200540.3A 2016-03-31 2016-03-31 Implantable medical device, data outputting and receiving methods thereof and communication mechanism Pending CN105892317A (en)

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Publication number Priority date Publication date Assignee Title
CN107362449A (en) * 2017-06-23 2017-11-21 西安交通大学 A kind of radio communication circuit structure and method applied to Implanted cardiac pacemaker
CN107875516A (en) * 2017-10-31 2018-04-06 乐普医学电子仪器股份有限公司 A kind of wireless communications method between implantable medical devices and vitro program controlled device
CN113663219A (en) * 2020-05-14 2021-11-19 上海神奕医疗科技有限公司 Implantable medical device and pulse generation method thereof

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CN104301973A (en) * 2014-10-30 2015-01-21 西安电子科技大学 Fast association wakeup method of wireless body area network
CN104606784A (en) * 2015-02-06 2015-05-13 上海微创医疗器械(集团)有限公司 Cardiac pacemaker system and control method thereof
CN104645499A (en) * 2015-03-16 2015-05-27 北京品驰医疗设备有限公司 In vitro controller of implantable medical device for patients

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Publication number Priority date Publication date Assignee Title
US20060113396A1 (en) * 2004-12-01 2006-06-01 Derocco Paul Implantable device and communication integrated circuit implementable therein
CN101926097A (en) * 2007-11-27 2010-12-22 普罗秋斯生物医学公司 Transbody communication systems employing communication channels
CN104225790A (en) * 2014-09-19 2014-12-24 清华大学 Closed loop nerve stimulation system
CN104301973A (en) * 2014-10-30 2015-01-21 西安电子科技大学 Fast association wakeup method of wireless body area network
CN104606784A (en) * 2015-02-06 2015-05-13 上海微创医疗器械(集团)有限公司 Cardiac pacemaker system and control method thereof
CN104645499A (en) * 2015-03-16 2015-05-27 北京品驰医疗设备有限公司 In vitro controller of implantable medical device for patients

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107362449A (en) * 2017-06-23 2017-11-21 西安交通大学 A kind of radio communication circuit structure and method applied to Implanted cardiac pacemaker
CN107875516A (en) * 2017-10-31 2018-04-06 乐普医学电子仪器股份有限公司 A kind of wireless communications method between implantable medical devices and vitro program controlled device
CN113663219A (en) * 2020-05-14 2021-11-19 上海神奕医疗科技有限公司 Implantable medical device and pulse generation method thereof

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Application publication date: 20160824