CN105770381A - Preparation taken by patients suffering from gastric ulcers and production method of preparation - Google Patents
Preparation taken by patients suffering from gastric ulcers and production method of preparation Download PDFInfo
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- CN105770381A CN105770381A CN201610267780.5A CN201610267780A CN105770381A CN 105770381 A CN105770381 A CN 105770381A CN 201610267780 A CN201610267780 A CN 201610267780A CN 105770381 A CN105770381 A CN 105770381A
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Abstract
The invention discloses a preparation taken by patients suffering from gastric ulcers. The preparation is mainly produced from the following raw material medicines in parts by mass: 5-15 parts of perilla leaves, 6-14 parts of cushaw stems, 4-9 parts of great burdock stems and leaves, 10-16 parts of psilotum nudum, 15-20 parts of thorny elaeagnus roots, 4-8 parts of lily flowers, 5-10 parts of rice beans, 3-7 parts of (calcined) clam shells, 7-14 parts of yellowflower toadlily herbs, 8-14 parts of Yunnan tylophora roots, 6-9 parts of caudate sweetleaf roots, 7-10 parts of hairyvein agrimonia herbs, 10-15 parts of spinach beet, 4-8 parts of beechey fig roots and 6-10 parts of citrus aurantium. The preparation disclosed by the invention is scientific in formula and synergistic in effects; obtained products have the efficacies of reducing swelling, easing pains, regulating the function of the stomach, stopping bleeding and the like, the treatment effects are good, recurrence can be effectively avoided, and the action time is long.
Description
Technical field
The present invention relates to traditional Chinese medicine field, particularly relate to preparation and preparation method that a kind of patients w ith peptic ulcer disease is taken.
Background technology
Gastric ulcer is a kind of fairly common digestive system disease, and its Etiological is owing to having infected H. pylori
Bacterium, and abuse NSAID (non-steroidal anti-inflammatory drug) etc..Abdominal pain is the cardinal symptom of gastric ulcer, and pain is positioned at epigastrium more, it is possible to go out
Now after left upper abdomen, breastbone or xiphoid-process, often in dull pain, dull pain, distending pain, burn the pain such as sample pain.The pain of gastric ulcer many
Occurring in 1 hour after the meal, gradually alleviated after 1～2 hour, until reappearing the above-mentioned rhythm and pace of moving things again after lower meal feed, part is suffered from
Person can be asymptomatic, or using complication such as hemorrhage, perforation as onset symptoms.For the treatment of gastric ulcer, current more options are damaged
Relatively low the medicine such as antacid, anticholinergic agent of factor, H2 receptor antagonist, proglumide, the synthetics of PGE2 and
Omeprazoles etc., give the medicine such as sucralfate, bismuth of gastric mucosal protection, carbenoxolone (carbenoxolone) etc. and antibiotic simultaneously
Application.
Publication No. CN 103386073 A(application number 201310345113.0) Chinese patent literature disclose one and control
Treating the Chinese medicine of gastric ulcer, the weight portion of crude drug composition is, roud cardamon seed 10-13, Fructus Toosendan 8-11, stir-fry Rhizoma Cyperi 7-11, Pericarpium Citri Reticulatae 8-
10, Rhizoma Acori Graminei 6-8, Fructus Mume 4-7, Radix Aucklandiae 3-5, Radix Bupleuri 4-6, Radix Et Rhizoma Nardostachyos 4-7, Herba Cistanches 2-4, Semen Raphani 2-5, Cortex Phellodendri 7-10, trifoliate orange
Shell 8-11, Rhizoma Alpiniae Officinarum 6-9, by above-mentioned 14 taste crude drug, be soaked in water, then decoct, filtrate of removing slag to obtain.Publication No. CN
104740014 A(application numbers 201310737297.5) Chinese patent literature disclose the prescription for the treatment of gastric ulcer, it is special
Point is: component: Pericarpium Citri Reticulatae, Endoconcha Sepiae, Radix Notoginseng, Rhizoma Corydalis, Fructus Evodiae, Radix Ginseng Rubra, Radix Bupleuri, the Radix Paeoniae Alba, orange；Every dose of amounts of components: old
Skin 10 grams, Endoconcha Sepiae 15 grams, Radix Notoginseng 15 grams, Rhizoma Corydalis 10 grams, Fructus Evodiae 10 grams, Radix Ginseng Rubra 10 grams, Radix Bupleuri 12 grams, the Radix Paeoniae Alba
15 grams, orange 10 grams.Publication No. CN 104258262 A(application number 201410553431.0) Chinese patent literature open
A kind of Chinese medicine treating gastric ulcer, is made up of the crude drug of following weight portion, Semen Oroxyli 77-87 part, Jacob's ladder 41-51 part, removes
The 25-35 of falling rice steamer part, Fructus Aristolochiae Kwangsiensis 33-43 part, Semen Aesculi 25-35 part, Fructus Citri Sarcodactylis 18-28 part, Herba Sedi Bulbiferi 21-31 part, Fructus Amomi Rotundus 19-29
Part, Bulbus Allii Macrostemonis 14-24 part, Semen Alpiniae Katsumadai 20-30 part, venushair fern 13-23 part, Semen Cuscutae 16-26 part, Rhizoma Dioscoreae Cirrhosae 10-20 part, Flos jasmini
37-47 part, Fructus Polygoni Orientalis 24-34 part, Herba pterocephali 26-36 part, Herba Polygoni cymosi 8-18 part, Rhizoma alpiniae pumilae 6-16 part, Rubus corchorifolius Linn. f. 8-18 part, will
It is soaked in water after the mixing of above-mentioned raw materials medicine, filtrate of removing slag after decocting to obtain.
The side effect of Western medicine long-term taking is relatively big the most on the market, has a strong impact on the healthy of patient, and mostly can not be thorough
The end, cures, and causes aggravation, therefore for improving therapeutic effect, can develop a kind of significantly more efficient Chinese medicine formula, safely and fast
Treatment gastric ulcer.
Summary of the invention
For the deficiencies in the prior art, it is an object of the invention to provide that a kind of curative effect is reliable, take safe gastric ulcer suffers from
Preparation that person takes and preparation method.
The technical scheme is that
The preparation that patients w ith peptic ulcer disease is taken, is mainly prepared from by following bulk drugs, is mass parts: Folium Perillae 5-15, Fructus Cucurbitae moschatae
Rattan 6-14, Caulis et Folium Arctii 4-9, Herba Psiloti Nudi 10-16, Radix Elaeagni 15-20, Flos Lilii viriduli 4-8, Semen Phaseoli 5-10, Concha Arcae (is forged)
3-7, Herba Tricyrtis Pilosae 7-14, Radix Tylophorae Yunnanensis 8-14, Radix Symplocoris Caudatae 6-9, Herba Agrimoniae 7-10, dish 10-15, Radix Fici beecheyanae 4-8, Citrus aurantium L. var. amara Engl.
6-10。
Preferred version is, Folium Perillae 7-13, Caulis Cucurbitae 8-12, Caulis et Folium Arctii 5-8, Herba Psiloti Nudi 12-14, Radix Elaeagni 16-
19, Flos Lilii viriduli 5-7, Semen Phaseoli 6-9, Concha Arcae (forging) 4-6, Herba Tricyrtis Pilosae 9-12, Radix Tylophorae Yunnanensis 10-12, Radix Symplocoris Caudatae 7-8, Herba Agrimoniae
8-9, dish 11-14, Radix Fici beecheyanae 5-7, Citrus aurantium L. var. amara Engl. 7-9.
It is more preferable that Folium Perillae 10, Caulis Cucurbitae 10, Caulis et Folium Arctii 6.5, Herba Psiloti Nudi 13, Radix Elaeagni 17.5, Bulbus Lilii
Spend 6, Semen Phaseoli 7.5, Concha Arcae (forging) 5, Herba Tricyrtis Pilosae 10.5, Radix Tylophorae Yunnanensis 11, Radix Symplocoris Caudatae 7.5, Herba Agrimoniae 8.5, dish 12.5,
Radix Fici beecheyanae 6, Citrus aurantium L. var. amara Engl. 8.
The preparation method of the soft extract of described preparation, step is as follows:
(1) take Folium Perillae, Caulis et Folium Arctii, Flos Lilii viriduli and Citrus aurantium L. var. amara Engl. to clean, add soda water moistening 18-28 minute (preferably: vexed
Moisten 20-26 minute；More preferably: moistening 23 minutes), taking out, slow fire is fried to being dried and pulverizing；
(2) Caulis Cucurbitae and dish remove impurity being cleaned, cut into chunks, be placed in frying pan, slow fire stir-fries 6-12 minute (preferably: literary composition
Fire stir-fries 9 minutes), taking-up is pulverized, and drenches and mixes 15 minutes into saline solution, then under the conditions of being placed in 45 DEG C, freeze-day with constant temperature；
(3) take Radix Elaeagni, Radix Tylophorae Yunnanensis, Radix Symplocoris Caudatae and Radix Fici beecheyanae to clean, be placed in washing water of rice and infiltrate 20-36 minute (preferably
: infiltrate 24-32 minute；More preferably: infiltrate 28 minutes), taking out section, drenching into concentration is the white vinegar of 10%, and constant temperature dries
Dry；
(4) Semen Phaseoli and Concha Arcae (forging) are placed in marmite, add the water of boiled crude drug quality 10-14 times (preferably: add
Enter the water of boiled crude drug quality 12 times), big fire decocts to boiling, adds Herba Psiloti Nudi, Herba Tricyrtis Pilosae and Herba Agrimoniae, changes little fire and continue
Continuous decoction, is collected by filtration filtrate, and filtering residue adds water and again decocts, and merges twice gained filtrate；
(5) step (1) (2) (3) made crude drug is pulverized, make medicated powder, add to step (4) gained filtrate, reduce pressure dense
It is reduced to thick paste, obtains soft extract.
The preparation method of described preparation soft extract, step (4) changes little fire and continues to decoct 30-44 minute (preferably: continue
Decoct 34-40 minute；More preferably: continue to decoct 37 minutes).
The preparation method of the decoction of described preparation, step is as follows:
(1) take Folium Perillae, Caulis et Folium Arctii, Flos Lilii viriduli and Citrus aurantium L. var. amara Engl. to clean, add soda water moistening 18-28 minute (preferably: vexed
Moisten 20-26 minute；More preferably: moistening 23 minutes), taking out, slow fire is fried to being dried and pulverizing；
(2) Caulis Cucurbitae and dish remove impurity being cleaned, cut into chunks, be placed in frying pan, slow fire stir-fries 6-12 minute (preferably: literary composition
Fire stir-fries 9 minutes), taking-up is pulverized, and drenches and mixes 15 minutes into saline solution, then under the conditions of being placed in 45 DEG C, freeze-day with constant temperature；
(3) take Radix Elaeagni, Radix Tylophorae Yunnanensis, Radix Symplocoris Caudatae and Radix Fici beecheyanae to clean, be placed in washing water of rice and infiltrate 20-36 minute (preferably
: infiltrate 24-32 minute；More preferably: infiltrate 28 minutes), taking out section, drenching into concentration is the white vinegar of 10%, and constant temperature dries
Dry；
(4) Semen Phaseoli and Concha Arcae (forging) are placed in marmite, add the water of boiled crude drug quality 10-14 times (preferably: add
Enter the water of boiled crude drug quality 12 times), big fire decocts to boiling, adds Herba Psiloti Nudi, Herba Tricyrtis Pilosae and Herba Agrimoniae, changes little fire and continue
Continuous decoction 35 minutes, is collected by filtration filtrate, and filtering residue adds water and again decocts, and merges twice gained filtrate；
(5) being pulverized and sieved by step (1) (2) (3) made crude drug, mix with step (4) gained filtrate, heating is concentrated into substance
Long-pending half, filters, obtains decoction.
The preparation method of described preparation decoction, step (5) pulverized 100-180 mesh sieve (preferably: pulverized 120-
160 mesh sieves；More preferably: pulverized 140 mesh sieves).
The preparation method of the pill of described preparation, step is as follows:
(1) take Folium Perillae, Caulis et Folium Arctii, Flos Lilii viriduli and Citrus aurantium L. var. amara Engl. to clean, add soda water moistening 18-28 minute (preferably: vexed
Moisten 20-26 minute；More preferably: moistening 23 minutes), taking out, slow fire is fried to being dried and pulverizing；
(2) Caulis Cucurbitae and dish remove impurity being cleaned, cut into chunks, be placed in frying pan, slow fire stir-fries 6-12 minute (preferably: literary composition
Fire stir-fries 9 minutes), taking-up is pulverized, and drenches and mixes 15 minutes into saline solution, then under the conditions of being placed in 45 DEG C, freeze-day with constant temperature；
(3) take Radix Elaeagni, Radix Tylophorae Yunnanensis, Radix Symplocoris Caudatae and Radix Fici beecheyanae to clean, be placed in washing water of rice and infiltrate 20-36 minute (preferably
: infiltrate 24-32 minute；More preferably: infiltrate 28 minutes), taking out section, drenching into concentration is the white vinegar of 10%, and constant temperature dries
Dry；
(4) Semen Phaseoli and Concha Arcae (forging) are placed in marmite, add the water of boiled crude drug quality 8-10 times (preferably: add
Enter the water of boiled crude drug quality 9 times), big fire decocts to boiling, adds Herba Psiloti Nudi, Herba Tricyrtis Pilosae and Herba Agrimoniae, changes little fire and continue
Continuous decoction 35 minutes, is collected by filtration filtrate, and filtering residue adds water and again decocts, and merges twice gained filtrate；
(5) step (1) (2) (3) made crude drug is pulverized, add to step (4) gained filtrate, be spray-dried, make medicine
Powder, adds that refined honey is general makes ball, is dried, packaging, makes pill.
The preparation method of described preparation pill, step (5) add refined honey amount be 0.1-0.3 times of medicated powder quality (preferably
: addition refined honey amount is 0.2 times of medicated powder quality).
The preparation method of the powder of described preparation, step is as follows:
(1) take Folium Perillae, Caulis et Folium Arctii, Flos Lilii viriduli and Citrus aurantium L. var. amara Engl. to clean, add soda water moistening 18-28 minute (preferably: vexed
Moisten 20-26 minute；More preferably: moistening 23 minutes), taking out, slow fire is fried to being dried and pulverizing；
(2) Caulis Cucurbitae and dish remove impurity being cleaned, cut into chunks, be placed in frying pan, slow fire stir-fries 6-12 minute (preferably: literary composition
Fire stir-fries 9 minutes), taking-up is pulverized, and drenches and mixes 15 minutes into saline solution, then under the conditions of being placed in 45 DEG C, freeze-day with constant temperature；
(3) take Radix Elaeagni, Radix Tylophorae Yunnanensis, Radix Symplocoris Caudatae and Radix Fici beecheyanae to clean, be placed in washing water of rice and infiltrate 20-36 minute (preferably
: infiltrate 24-32 minute；More preferably: infiltrate 28 minutes), taking out section, drenching into concentration is the white vinegar of 10%, and constant temperature dries
Dry；
(4) Semen Phaseoli and Concha Arcae (forging) are placed in marmite, add the water of boiled crude drug quality 8-12 times (preferably: add
Enter the water of boiled crude drug quality 10 times), big fire decocts to boiling, adds Herba Psiloti Nudi, Herba Tricyrtis Pilosae and Herba Agrimoniae, changes little fire and continue
Continuous decoction 35 minutes, is collected by filtration filtrate, and filtering residue adds water and again decocts, and merges twice gained filtrate；
(5) heating concentration step (4) gained filtrate, pulverizes and sieves after drying together with step (1) (2) (3) made crude drug, system
Become medicated powder, obtain powder.
The preparation method of described preparation powder, step (5) pulverized 200-280 mesh sieve (preferably: pulverized 220-
260 mesh sieves；More preferably: pulverized 240 mesh sieves).
The preparation not only scientific formula that the patients w ith peptic ulcer disease that the present invention provides is taken, and preparation method is simple, product is taken
Convenient.In addition, the excellent results of the present invention is also manifested by:
1, therapeutic effect of the present invention is good, can effectively prevent recurrence, long action time；
2, this prescription complies fully with Chinese medicine principle, has the effect such as reducing swelling and alleviating pain, stomach function regulating hemostasis；
3, materials safety of the present invention has no side effect, cheap, does not increase patient burden.
Detailed description of the invention
Describe technical scheme in detail below in conjunction with embodiment and experimental example, but protection domain is not limited to this.
Used by the present invention, the pharmacology of main raw material of Chinese medicine is as follows:
Folium Perillae: base: for the leaf of labiate wrinkle Folium Perillae, point Folium Perillae etc..Nature and flavor: pungent, temperature.Gui Jing: enter lung, spleen channel.Merit
Can cure mainly: expelling cold and relieving exterior syndrome；Dispersing lung-QI and dissipating phlegm；Circulation of qi promoting and in；Antiabortive；Cowfish Eriocheir sinensis poison.Main exterior syndrome due to wind-cold；Cough with copious phlegm；Crisp distension；Dislike
The heart is vomitted；Stomachache is vomited and diarrhoea；Nausea is got along well；Gestation dislikes the moon；Ichthyophagy Eriocheir sinensis is poisoned.
Caulis Cucurbitae: base: for the stem of cucurbitaceous plant Fructus Cucurbitae moschatae.Nature and flavor: sweet in the mouth；Bitter；Cold nature.Gui Jing: enter liver；Stomach；Lung
Warp.Function cures mainly: lung heat clearing；Suppressing the hyperactive liver；Stomach function regulating；Dredging collateral.Main pulmonary tuberculosis low grade fever；Stomachache due to hyperactive liver-QI attacking the stomach；Menoxenia；Acute catarrhal conjunctivitis swelling pain；Extreme misery scalds
Wound.
Caulis et Folium Arctii: base: for the stem and leaf of feverfew Fructus Arctii.Nature and flavor: bitter in the mouth；Micro-sweet；Cool in nature.Function cures mainly: heat clearing away
Relieving restlessness；Reducing swelling and alleviating pain.Main headache due to pathogenic wind-heat；Vexed xerostomia；Laryngopharynx swelling and pain；Urine is puckery few；Carbuncle furuncle；Skin pruritus due to wind pathogen；Seborrhea ichthyosis.
Herba Psiloti Nudi: base: for the herb of Psilotaceae plant Psilotum nudum.Nature and flavor: sweet；Pungent；Temperature；Nontoxic；Puckery.Gui Jing: the heart；
Liver；Stomach warp.Function cures mainly: promoting blood circulation and hemostasis；Stimulate the menstrual flow；Expelling wind and removing dampness.Main air pain of dampness syndrome；Women's amenorrhea；Spit blood；Traumatic injury；Wind
Rash.
Radix Elaeagni: base: for the root of Elaeangnaceae plant Fructus Elaeagni.Nature and flavor: bitter in the mouth；Acid；Property flat.Gui Jing: lung；Spleen
Warp.Function cures mainly: promoting blood circulation and hemostasis；Expelling wind and removing dampness；Relieving cough and asthma；Removing toxic substances sore.Main taste blood；Spitting of blood；Have blood in stool；Menorrhagia；Wind
Wet arthralgia；Jaundice；Edema；Dysentery；Infantile malnutrition；Cough with asthma；Laryngopharynx swelling and pain；Skin ulcer scabies；Injury from falling down.
Flos Lilii viriduli: base: for the flower of liliaceous plant Bulbus Lilii, tiger lily, Bulbus lilii concoloris or Bulbus Lilii.Nature and flavor: sweet；Bitter；It is slightly cold.Return
Warp: lung.Function cures mainly: clearing heat and moistening lung；Mind tranquilizing and the heart calming.Main cough expectorant is few or viscous；Dizziness；Uneasy sleeping at night；It bleb eczema.
Semen Phaseoli: base: for leguminous plant Semen Phaseoli or the seed of Semen Phaseoli.Nature and flavor: sweet in the mouth；Acid；Cold nature.Gui Jing: the heart；
Spleen；Kidney；Small intestine meridian.Function cures mainly: inducing diuresis to remove edema jaundice eliminating；Heat-clearing and toxic substances removing eliminating carbuncle.Main edema；Tinea pedis；Jaundice；Gonorrhea；Have blood in stool；Swollen
Skin infection infections；Scall.
Concha Arcae (is forged): base: for Carnis Arca inflata section animal Scapharca subcrenata, Tegillarca granosa or the shell of Scapharca broughtonii.Take clean Concha Arcae and put in container, in
In smokeless stove fire, being calcined to crisp, taking-up cools, and pulverizes.Concha Arcae (calcined) is used for relieving gastric hyperacidity to alleviate stomachache.Nature and flavor with return through: salty, flat.Return
Lung, stomach, Liver Channel.Function with cure mainly: expectorant blood stasis dispelling, hard masses softening and resolving, relieving gastric hyperacidity to alleviate stomachache.Cementing for pertinacious phlegm, sticky difficulty is coughed up, goiter,
Scrofula, addiction abdominal mass mass in the abdomen, pantothenic acid of having a stomachache.
Herba Tricyrtis Pilosae: base: for the herb of liliaceous plant Hemerocallis citrina Baroni Herba Tricyrtidis macropodae.Nature and flavor: sweet；Cold nature.Function cures mainly: heat clearing away
Relieving restlessness；Promoting blood circulation and detumescence.Main gastric heat is thirsty；Dysphoria；Impairment caused by overstrain；Edema.
Radix Tylophorae Yunnanensis: base: for the root of dicotyledon Yao Luo section plant Yunnan Radix tylophorae floribundae.Nature and flavor: bitter in the mouth, pungent；Property is micro-
Temperature.Gui Jing: liver；Spleen channel.Function cures mainly: Kuai, a state in the Zhou Dynasty dish dredging collateral；Promoting blood circulation and stopping pain.Main rheumatic ostalgia hepatitis, gastric ulcer, lose after poliomyelitis
Disease, traumatic injury.
Radix Symplocoris Caudatae: base: for the root of Symplocaceae plant mountain vitriol.Nature and flavor: bitter；Pungent；Property flat.Gui Jing: liver, stomach warp.Function master
Control: clearing away heat-damp and promoting diuresis；Cooling blood for hemostasis；Wind-expelling pain-stopping.Main jaundice；Have loose bowels；Dysentery；Metrorrhagia；Acute toothache；Headache；Rheumatic arthralgia.
Herba Agrimoniae: base: for the dry aerial parts of rosaceous plant Agrimony.Nature and flavor with return through: bitter, puckery, flat.Return
The heart, Liver Channel.Function with cure mainly: astringing to arrest bleeding, preventing the attack (or recurrence) of malaria, dysentery relieving, removing toxic substances, qi-restoratives.For spitting blood, spit blood, metrostaxis, malaria,
Dysentery, carbuncle sore tumefacting virus, pudendal pruritus leukorrhagia, de-power impairment caused by overstrain.
Dish: base: plant the stem of plant dish, leaf for multitude.Nature and flavor: sweet；Bitter；Cold in nature.Gui Jing: lung；Kidney；Large intestine
Warp.Function cures mainly: heat-clearing and toxic substances removing；Clots absorbing stops blooding.Row calentura time main；Hemorrhoid；Measles without adequate eruption；Spit blood；Pyretic toxicity dysentery；Close
Warp；Stranguria with turbid discharge；Carbuncle；Traumatic injury；Snakeworm hinders.
Radix Fici beecheyanae: base: for the root of moraceae plants Fructus Fici Beecheyanae.Nature and flavor: sweet；Pungent；Warm in nature.Gui Jing: lung；Spleen；Kidney channel.Merit
Can cure mainly: replenishing QI to invigorate the spleen；Promoting blood circulation to remove obstruction in the collateral；Expelling wind and removing dampness.Main overstrain is weak；Lack of appetite；Agalactia；Insufficiency of the spleen leucorrhea；Proctoptosis；Menstruation
Uncomfortable；Wind syndrome of head pain；Traumatic injury；Rheumatic arthralgia.
Citrus aurantium L. var. amara Engl.: base: for the alabastrum of rutaceae Citrus aurantium L. var. amara Engl..Nature and flavor: pungent；Sweet；Micro-hardship；Property flat.Function cures mainly: reason
Gas the chest stuffiness relieving；Stomach function regulating preventing or arresting vomiting.Main painful abdominal mass in the heart is vexed；Abdominal distention；Anorexia；Nausea and vomiting.
The preparation that embodiment 1 patients w ith peptic ulcer disease is taken, is mainly prepared from (every part of 10g) by following bulk drugs: Folium Perillae
5 parts, Caulis Cucurbitae 6 parts, Caulis et Folium Arctii 4 parts, Herba Psiloti Nudi 10 parts, Radix Elaeagni 15 parts, Flos Lilii viriduli 4 parts, Semen Phaseoli 5 parts, Concha Arcae
(forging) 3 parts, Herba Tricyrtis Pilosae 7 parts, Radix Tylophorae Yunnanensis 8 parts, Radix Symplocoris Caudatae 6 parts, Herba Agrimoniae 7 parts, dish 10 parts, Radix Fici beecheyanae 4 parts, Citrus aurantium L. var. amara Engl.
6 parts.The preparation method of the preparation soft extract that above-mentioned patients w ith peptic ulcer disease is taken is:
(1) taking Folium Perillae, Caulis et Folium Arctii, Flos Lilii viriduli and Citrus aurantium L. var. amara Engl. to clean, add soda water moistening 23 minutes, take out, slow fire is fried
To being dried and pulverizing；
(2) Caulis Cucurbitae and dish remove impurity being cleaned, cut into chunks, be placed in frying pan, slow fire stir-fries 9 minutes, and taking-up is pulverized, drench into
Saline solution mixes 15 minutes, then under the conditions of being placed in 45 DEG C, freeze-day with constant temperature；
(3) taking Radix Elaeagni, Radix Tylophorae Yunnanensis, Radix Symplocoris Caudatae and Radix Fici beecheyanae to clean, be placed in washing water of rice infiltration 28 minutes, taking-up is cut
Sheet, drenching into concentration is the white vinegar of 10%, constant temperature drying；
(4) Semen Phaseoli and Concha Arcae (forging) being placed in marmite, add the water of boiled crude drug quality 12 times, big fire decocts to boiling
Rising, add Herba Psiloti Nudi, Herba Tricyrtis Pilosae and Herba Agrimoniae, change little fire and continue to decoct 37 minutes, filtrate is collected by filtration, filtering residue adds water again
Decoct, merge twice gained filtrate；
(5) step (1) (2) (3) made crude drug is pulverized, make medicated powder, add to step (4) gained filtrate, reduce pressure dense
It is reduced to thick paste, obtains soft extract.
The preparation that embodiment 2 patients w ith peptic ulcer disease is taken, is mainly prepared from (every part of 10g) by following bulk drugs: Folium Perillae
15 parts, Caulis Cucurbitae 14 parts, Caulis et Folium Arctii 9 parts, Herba Psiloti Nudi 16 parts, Radix Elaeagni 20 parts, Flos Lilii viriduli 8 parts, Semen Phaseoli 10 parts, Concha Arcae
Son (forging) 7 parts, Herba Tricyrtis Pilosae 14 parts, Radix Tylophorae Yunnanensis 14 parts, Radix Symplocoris Caudatae 9 parts, Herba Agrimoniae 10 parts, dish 15 parts, Radix Fici beecheyanae 8 parts,
Citrus aurantium L. var. amara Engl. 10 parts.The preparation method of the preparation decoction that patients w ith peptic ulcer disease is taken is:
(1) taking Folium Perillae, Caulis et Folium Arctii, Flos Lilii viriduli and Citrus aurantium L. var. amara Engl. to clean, add soda water moistening 23 minutes, take out, slow fire is fried
To being dried and pulverizing；
(2) Caulis Cucurbitae and dish remove impurity being cleaned, cut into chunks, be placed in frying pan, slow fire stir-fries 9 minutes, and taking-up is pulverized, drench into
Saline solution mixes 15 minutes, then under the conditions of being placed in 45 DEG C, freeze-day with constant temperature；
(3) taking Radix Elaeagni, Radix Tylophorae Yunnanensis, Radix Symplocoris Caudatae and Radix Fici beecheyanae to clean, be placed in washing water of rice infiltration 28 minutes, taking-up is cut
Sheet, drenching into concentration is the white vinegar of 10%, constant temperature drying；
(4) Semen Phaseoli and Concha Arcae (forging) being placed in marmite, add the water of boiled crude drug quality 12 times, big fire decocts to boiling
Rising, add Herba Psiloti Nudi, Herba Tricyrtis Pilosae and Herba Agrimoniae, change little fire and continue to decoct 35 minutes, filtrate is collected by filtration, filtering residue adds water again
Decoct, merge twice gained filtrate；
(5) step (1) (2) (3) made crude drug being pulverized 140 mesh sieves, and mixed with step (4) gained filtrate, heating concentrates
To the half of original volume, filter, obtain decoction.
Model case: xxx, female, 36 years old.Main suit: epigastrium pain, acid regurgitation are felt sick；Medical history: patient starts to subtract the year before
Fertilizer, diet is irregular, causes body constitution to decline, and periodically pain occurs in epigastrium the most over the past half year, occasionally has acid regurgitation and feels sick
Uncomfortable disease, appetite is poor, sleeps poor, and gastroscopy of being admitted to hospital is diagnosed as gastric ulcer.
Take the preparation decoction that the present embodiment gained patients w ith peptic ulcer disease is taken, every day 2 times, each 150-250ml, warm clothes
With, 10 days courses for the treatment of.After patient takes five days, pain symptom alleviates, and continues to take two courses for the treatment of, and uncomfortable disease substantially eliminates,
Appetite is normal, check display, and ulcer eliminates, and after consolidating one week, patient fully recovers, and follows up a case by regular visits to, in 1 year, not recur.
The preparation that embodiment 3 patients w ith peptic ulcer disease is taken, is mainly prepared from (every part of 10g) by following bulk drugs: Folium Perillae
7 parts, Caulis Cucurbitae 8 parts, Caulis et Folium Arctii 5 parts, Herba Psiloti Nudi 12 parts, Radix Elaeagni 16 parts, Flos Lilii viriduli 5 parts, Semen Phaseoli 6 parts, Concha Arcae
(forging) 4 parts, Herba Tricyrtis Pilosae 9 parts, Radix Tylophorae Yunnanensis 10 parts, Radix Symplocoris Caudatae 7 parts, Herba Agrimoniae 8 parts, dish 11 parts, Radix Fici beecheyanae 5 parts, turtle turtle
Spend 7 parts.The preparation method of the preparation pill that patients w ith peptic ulcer disease is taken is:
(1) taking Folium Perillae, Caulis et Folium Arctii, Flos Lilii viriduli and Citrus aurantium L. var. amara Engl. to clean, add soda water moistening 23 minutes, take out, slow fire is fried
To being dried and pulverizing；
(2) Caulis Cucurbitae and dish remove impurity being cleaned, cut into chunks, be placed in frying pan, slow fire stir-fries 9 minutes, and taking-up is pulverized, drench into
Saline solution mixes 15 minutes, then under the conditions of being placed in 45 DEG C, freeze-day with constant temperature；
(3) taking Radix Elaeagni, Radix Tylophorae Yunnanensis, Radix Symplocoris Caudatae and Radix Fici beecheyanae to clean, be placed in washing water of rice infiltration 28 minutes, taking-up is cut
Sheet, drenching into concentration is the white vinegar of 10%, constant temperature drying；
(4) Semen Phaseoli and Concha Arcae (forging) being placed in marmite, add the water of boiled crude drug quality 9 times, big fire decocts to boiling
Rising, add Herba Psiloti Nudi, Herba Tricyrtis Pilosae and Herba Agrimoniae, change little fire and continue to decoct 35 minutes, filtrate is collected by filtration, filtering residue adds water again
Decoct, merge twice gained filtrate；
(5) step (1) (2) (3) made crude drug is pulverized, add to step (4) gained filtrate, be spray-dried, make medicine
Powder, the refined honey of addition medicated powder quality 0.2 times is general makes ball, is dried, packs, makes pill.
Model case: xxx, man, 28 years old.Medical history: recurrent abdominal pain distending pain 1 year；Medical history: patient often stays up late overtime work, drink
Eat irregular, from starting that abdominal part distending pain occurs the year before, have feeling of repletion after meal, and with the symptom such as acid regurgitation, gas, be on inspection
Gastric ulcer, once took western medicine, remission, but two months ago, conditions of patients recurred again, then sought treatment by Chinese herbs.
Take the preparation pill that the present embodiment gained patients w ith peptic ulcer disease is taken, use every day 2 times, each 2-3 grain, open by temperature
Mixing in water for oral taking, 10 days courses for the treatment of.After patient takes a course for the treatment of, abdominal part distending pain is alleviated, and acid regurgitation eliminates, after taking two courses for the treatment of,
Symptom substantially eliminates, and spirit takes a turn for the better, and continues to take drug withdrawal after the course for the treatment of, and patient checks, and the state of an illness is fully recovered.
The preparation that embodiment 4 patients w ith peptic ulcer disease is taken, is mainly prepared from (every part of 10g) by following bulk drugs: Folium Perillae
13 parts, Caulis Cucurbitae 12 parts, Caulis et Folium Arctii 8 parts, Herba Psiloti Nudi 14 parts, Radix Elaeagni 19 parts, Flos Lilii viriduli 7 parts, Semen Phaseoli 9 parts, Concha Arcae
Son (forging) 6 parts, Herba Tricyrtis Pilosae 12 parts, Radix Tylophorae Yunnanensis 12 parts, Radix Symplocoris Caudatae 8 parts, Herba Agrimoniae 9 parts, dish 14 parts, Radix Fici beecheyanae 7 parts, turtle
Turtle spends 9 parts.The preparation method of the preparation powder that patients w ith peptic ulcer disease is taken is:
(1) taking Folium Perillae, Caulis et Folium Arctii, Flos Lilii viriduli and Citrus aurantium L. var. amara Engl. to clean, add soda water moistening 23 minutes, take out, slow fire is fried
To being dried and pulverizing；
(2) Caulis Cucurbitae and dish remove impurity being cleaned, cut into chunks, be placed in frying pan, slow fire stir-fries 9 minutes, and taking-up is pulverized, drench into
Saline solution mixes 15 minutes, then under the conditions of being placed in 45 DEG C, freeze-day with constant temperature；
(3) taking Radix Elaeagni, Radix Tylophorae Yunnanensis, Radix Symplocoris Caudatae and Radix Fici beecheyanae to clean, be placed in washing water of rice infiltration 28 minutes, taking-up is cut
Sheet, drenching into concentration is the white vinegar of 10%, constant temperature drying；
(4) Semen Phaseoli and Concha Arcae (forging) being placed in marmite, add the water of boiled crude drug quality 10 times, big fire decocts to boiling
Rising, add Herba Psiloti Nudi, Herba Tricyrtis Pilosae and Herba Agrimoniae, change little fire and continue to decoct 35 minutes, filtrate is collected by filtration, filtering residue adds water again
Decoct, merge twice gained filtrate；
(5) heating concentration step (4) gained filtrate, pulverized 240 mesh after drying together with step (1) (2) (3) made crude drug
Sieve, makes medicated powder, obtains powder.
Model case: xxx, man, 48 years old.Medical history: patient's persistence epigastrium pain 3 years, and with acid regurgitation, feel sick or
Vomiting, always by the alleviation state of an illness of taking medicine, exacerbation of symptoms in nearly month during beginning, invalid after taking medicine, admission examination, gastroscope shows
Ulcer circular seen from stomach, and stool blood is positive, is diagnosed as gastric ulcer hemorrhage.
Take the preparation powder that the present embodiment gained patients w ith peptic ulcer disease is taken, use every day 2 times, each 4-6g, opens by temperature
Mixing in water for oral taking, 10 days courses for the treatment of.After patient takes one week, pain is slightly alleviated, and appetite strengthens, after adhering to taking two courses for the treatment of,
Acid regurgitation, the uncomfortable disease such as feel sick substantially alleviate, and consolidate a course for the treatment of, and disease all eliminates, check display, and gastric ulcer is fully recovered, and follows up a case by regular visits to
In 1 year, have no recurrence.
The preparation that embodiment 5 patients w ith peptic ulcer disease is taken, is mainly prepared from (every part of 10g) by following bulk drugs: Folium Perillae
10 parts, Caulis Cucurbitae 10 parts, Caulis et Folium Arctii 6.5 parts, Herba Psiloti Nudi 13 parts, Radix Elaeagni 17.5 parts, Flos Lilii viriduli 6 parts, Semen Phaseoli 7.5
Part, Concha Arcae (forging) 5 parts, Herba Tricyrtis Pilosae 10.5 parts, Radix Tylophorae Yunnanensis 11 parts, Radix Symplocoris Caudatae 7.5 parts, Herba Agrimoniae 8.5 parts, dish 12.5
Part, Radix Fici beecheyanae 6 parts, Citrus aurantium L. var. amara Engl. 8 parts.The preparation method of the preparation soft extract that patients w ith peptic ulcer disease is taken is:
(1) taking Folium Perillae, Caulis et Folium Arctii, Flos Lilii viriduli and Citrus aurantium L. var. amara Engl. to clean, add soda water moistening 23 minutes, take out, slow fire is fried
To being dried and pulverizing；
(2) Caulis Cucurbitae and dish remove impurity being cleaned, cut into chunks, be placed in frying pan, slow fire stir-fries 9 minutes, and taking-up is pulverized, drench into
Saline solution mixes 15 minutes, then under the conditions of being placed in 45 DEG C, freeze-day with constant temperature；
(3) taking Radix Elaeagni, Radix Tylophorae Yunnanensis, Radix Symplocoris Caudatae and Radix Fici beecheyanae to clean, be placed in washing water of rice infiltration 28 minutes, taking-up is cut
Sheet, drenching into concentration is the white vinegar of 10%, constant temperature drying；
(4) Semen Phaseoli and Concha Arcae (forging) being placed in marmite, add the water of boiled crude drug quality 12 times, big fire decocts to boiling
Rising, add Herba Psiloti Nudi, Herba Tricyrtis Pilosae and Herba Agrimoniae, change little fire and continue to decoct 37 minutes, filtrate is collected by filtration, filtering residue adds water again
Decoct, merge twice gained filtrate；
(5) step (1) (2) (3) made crude drug is pulverized, make medicated powder, add to step (4) gained filtrate, reduce pressure dense
It is reduced to thick paste, obtains soft extract.
The clinical practice of the preparation (embodiment 5) that test example 1 gained of the present invention patients w ith peptic ulcer disease is taken:
Choose crowd: in February, 2015 in December ,-2015, according to medical case history, the patients w ith peptic ulcer disease that screening is accepted for medical treatment in four hospitals
279 examples, age 18-62 year, 44.5 ± 1.6 years old mean age, the course of disease 6 months-6 years, wherein male patient 153 example, women suffer from
Person 126 example.All patients all check through gastroscope etc. and make a definite diagnosis, and not taking antibiotic or antisecretory before inspection, selected patient rejects
Gastric cancer, cirrhosis patients in decompensation, hematological system tumor and lower digestive tract hemorrhage patient, and follow the principle of voluntariness.
Before test, patient being randomly divided into two groups, experimental group 155 example and matched group 124 example, two groups in sex, age, disease
The aspect such as journey, the state of an illness is without significant difference.Experimental group takes products obtained therefrom of the present invention, each 6-8g, and one day twice, warm water is rushed
Clothes, 10 days are a course for the treatment of；Matched group takes other conventional medicines (omeprazole, bismuth potassium citrate, ranitidine etc.).The medication phase
Between two groups of patients are carried out Continuous Observation, record symptom and change.
Curative effect determinate standard: reference literature criterion of therapeutical effect, (1) cures: without the pain symptom of ulcer, through gastroscopy ulcer
Healing；(2) effective: substantially to heal through gastroscopy ulcer, occasionally there is unconspicuous canker sores symptom；(3) effective: to examine through gastroscope
Looking into ulcer healing reduction of area little by more than 50%, canker sores symptom still has；(4) invalid: to reduce through gastroscopy ulcer healing area
Less than 50%, canker sores symptom is for improving or increasing the weight of.
Clinical effectiveness: after the treatment of four courses for the treatment of, the therapeutic outcome of two groups is as shown in table 1:
The therapeutic outcome of 1 liang of table group
As shown in Table 1, the cure rate of experimental group is 69.0%, and total effective rate is 98.1%, and the cure rate of matched group is 51.6%,
Total effective rate is 88.7%, and contrast understands, and the therapeutic effect of experimental group is apparently higher than matched group, and experimental group recurs 8 examples, recurrence
Rate is 5.3%, and matched group recurs 22 examples, and relapse rate is 20.0%, illustrates that products obtained therefrom of the present invention can effectively treat gastric ulcer, prevents
The state of an illness recurs again.
Chinese medicine used in the present invention, Folium Perillae circulation of qi promoting and in, Caulis Cucurbitae stomach function regulating dredging collateral, Caulis et Folium Arctii reducing swelling and alleviating pain,
Herba Psiloti Nudi promoting blood circulation and hemostasis, Radix Elaeagni expelling wind and removing dampness, Flos Lilii viriduli clearing heat and moistening lung, Semen Phaseoli inducing diuresis to remove edema, Concha Arcae relieving gastric hyperacidity to alleviate stomachache,
Herba Tricyrtis Pilosae promoting blood circulation and detumescence, Radix Tylophorae Yunnanensis promoting blood circulation and stopping pain, Radix Symplocoris Caudatae cooling blood for hemostasis, Herba Agrimoniae astringing to arrest bleeding, dish clots absorbing stops blooding, cattle
Milk slurry root replenishing QI to invigorate the spleen, Citrus aurantium L. var. amara Engl. stomach function regulating preventing or arresting vomiting, multiple medical material synergism, play reducing swelling and alleviating pain, effect of stomach function regulating hemostasis altogether, can
Recover stomach function.
It should be pointed out that, the detailed description of the invention more representational example that is the present invention, it is clear that the skill of the present invention
Art scheme is not limited to above-described embodiment, it is also possible to have many variations.Those of ordinary skill in the art, the most public with present invention institute
What what that open or according to file written description was undoubted obtained, all it is considered as this patent scope of the claimed.
Claims (10)
1. the preparation that patients w ith peptic ulcer disease is taken, it is characterised in that be mainly prepared from by following bulk drugs, be mass parts: purple
Folium Perillae 5-15, Caulis Cucurbitae 6-14, Caulis et Folium Arctii 4-9, Herba Psiloti Nudi 10-16, Radix Elaeagni 15-20, Flos Lilii viriduli 4-8, Semen Phaseoli 5-
10, Concha Arcae (forging) 3-7, Herba Tricyrtis Pilosae 7-14, Radix Tylophorae Yunnanensis 8-14, Radix Symplocoris Caudatae 6-9, Herba Agrimoniae 7-10, dish 10-15, milk
Slurry root 4-8, Citrus aurantium L. var. amara Engl. 6-10.
2. the preparation that patients w ith peptic ulcer disease as claimed in claim 1 is taken, it is characterised in that Folium Perillae 7-13, Caulis Cucurbitae 8-12,
Caulis et Folium Arctii 5-8, Herba Psiloti Nudi 12-14, Radix Elaeagni 16-19, Flos Lilii viriduli 5-7, Semen Phaseoli 6-9, Concha Arcae (forging) 4-6, stain
Grass 9-12, Radix Tylophorae Yunnanensis 10-12, Radix Symplocoris Caudatae 7-8, Herba Agrimoniae 8-9, dish 11-14, Radix Fici beecheyanae 5-7, Citrus aurantium L. var. amara Engl. 7-9(is preferred
: Folium Perillae 10, Caulis Cucurbitae 10, Caulis et Folium Arctii 6.5, Herba Psiloti Nudi 13, Radix Elaeagni 17.5, Flos Lilii viriduli 6, Semen Phaseoli 7.5, watt
Stupefied son (forging) 5, Herba Tricyrtis Pilosae 10.5, Radix Tylophorae Yunnanensis 11, Radix Symplocoris Caudatae 7.5, Herba Agrimoniae 8.5, dish 12.5, Radix Fici beecheyanae 6, Citrus aurantium L. var. amara Engl.
8).
3. the preparation method of the soft extract of the preparation as described in claim 1-2 is arbitrary, it is characterised in that step is as follows:
(1) take Folium Perillae, Caulis et Folium Arctii, Flos Lilii viriduli and Citrus aurantium L. var. amara Engl. to clean, add soda water moistening 18-28 minute (preferably: vexed
Moisten 20-26 minute；More preferably: moistening 23 minutes), taking out, slow fire is fried to being dried and pulverizing；
(2) Caulis Cucurbitae and dish remove impurity being cleaned, cut into chunks, be placed in frying pan, slow fire stir-fries 6-12 minute (preferably: literary composition
Fire stir-fries 9 minutes), taking-up is pulverized, and drenches and mixes 15 minutes into saline solution, then under the conditions of being placed in 45 DEG C, freeze-day with constant temperature；
(3) take Radix Elaeagni, Radix Tylophorae Yunnanensis, Radix Symplocoris Caudatae and Radix Fici beecheyanae to clean, be placed in washing water of rice and infiltrate 20-36 minute (preferably
: infiltrate 24-32 minute；More preferably: infiltrate 28 minutes), taking out section, drenching into concentration is the white vinegar of 10%, and constant temperature dries
Dry；
(4) Semen Phaseoli and Concha Arcae (forging) are placed in marmite, add the water of boiled crude drug quality 10-14 times (preferably: add
Enter the water of boiled crude drug quality 12 times), big fire decocts to boiling, adds Herba Psiloti Nudi, Herba Tricyrtis Pilosae and Herba Agrimoniae, changes little fire and continue
Continuous decoction, is collected by filtration filtrate, and filtering residue adds water and again decocts, and merges twice gained filtrate；
(5) step (1) (2) (3) made crude drug is pulverized, make medicated powder, add to step (4) gained filtrate, reduce pressure dense
It is reduced to thick paste, obtains soft extract.
4. the preparation method of preparation soft extract as claimed in claim 3, it is characterised in that step (4) changes little fire and continues to decoct
30-44 minute (preferably: continue to decoct 34-40 minute；More preferably: continue to decoct 37 minutes).
5. the preparation method of the decoction of the preparation as described in claim 1-2 is arbitrary, it is characterised in that step is as follows:
(1) take Folium Perillae, Caulis et Folium Arctii, Flos Lilii viriduli and Citrus aurantium L. var. amara Engl. to clean, add soda water moistening 18-28 minute (preferably: vexed
Moisten 20-26 minute；More preferably: moistening 23 minutes), taking out, slow fire is fried to being dried and pulverizing；
(2) Caulis Cucurbitae and dish remove impurity being cleaned, cut into chunks, be placed in frying pan, slow fire stir-fries 6-12 minute (preferably: literary composition
Fire stir-fries 9 minutes), taking-up is pulverized, and drenches and mixes 15 minutes into saline solution, then under the conditions of being placed in 45 DEG C, freeze-day with constant temperature；
(3) take Radix Elaeagni, Radix Tylophorae Yunnanensis, Radix Symplocoris Caudatae and Radix Fici beecheyanae to clean, be placed in washing water of rice and infiltrate 20-36 minute (preferably
: infiltrate 24-32 minute；More preferably: infiltrate 28 minutes), taking out section, drenching into concentration is the white vinegar of 10%, and constant temperature dries
Dry；
(4) Semen Phaseoli and Concha Arcae (forging) are placed in marmite, add the water of boiled crude drug quality 10-14 times (preferably: add
Enter the water of boiled crude drug quality 12 times), big fire decocts to boiling, adds Herba Psiloti Nudi, Herba Tricyrtis Pilosae and Herba Agrimoniae, changes little fire and continue
Continuous decoction 35 minutes, is collected by filtration filtrate, and filtering residue adds water and again decocts, and merges twice gained filtrate；
(5) being pulverized and sieved by step (1) (2) (3) made crude drug, mix with step (4) gained filtrate, heating is concentrated into substance
Long-pending half, filters, obtains decoction.
6. the preparation method of preparation decoction as claimed in claim 5, it is characterised in that step (5) pulverized 100-180 mesh sieve
(preferably: pulverized 120-160 mesh sieve；More preferably: pulverized 140 mesh sieves).
7. the preparation method of the pill of the preparation as described in claim 1-2 is arbitrary, it is characterised in that step is as follows:
(1) take Folium Perillae, Caulis et Folium Arctii, Flos Lilii viriduli and Citrus aurantium L. var. amara Engl. to clean, add soda water moistening 18-28 minute (preferably: vexed
Moisten 20-26 minute；More preferably: moistening 23 minutes), taking out, slow fire is fried to being dried and pulverizing；
(2) Caulis Cucurbitae and dish remove impurity being cleaned, cut into chunks, be placed in frying pan, slow fire stir-fries 6-12 minute (preferably: literary composition
Fire stir-fries 9 minutes), taking-up is pulverized, and drenches and mixes 15 minutes into saline solution, then under the conditions of being placed in 45 DEG C, freeze-day with constant temperature；
(3) take Radix Elaeagni, Radix Tylophorae Yunnanensis, Radix Symplocoris Caudatae and Radix Fici beecheyanae to clean, be placed in washing water of rice and infiltrate 20-36 minute (preferably
: infiltrate 24-32 minute；More preferably: infiltrate 28 minutes), taking out section, drenching into concentration is the white vinegar of 10%, and constant temperature dries
Dry；
(4) Semen Phaseoli and Concha Arcae (forging) are placed in marmite, add the water of boiled crude drug quality 8-10 times (preferably: add
Enter the water of boiled crude drug quality 9 times), big fire decocts to boiling, adds Herba Psiloti Nudi, Herba Tricyrtis Pilosae and Herba Agrimoniae, changes little fire and continue
Continuous decoction 35 minutes, is collected by filtration filtrate, and filtering residue adds water and again decocts, and merges twice gained filtrate；
(5) step (1) (2) (3) made crude drug is pulverized, add to step (4) gained filtrate, be spray-dried, make medicine
Powder, adds that refined honey is general makes ball, is dried, packaging, makes pill.
8. the preparation method of preparation pill as claimed in claim 7, it is characterised in that it is medicated powder that step (5) adds refined honey amount
0.1-0.3 times (preferably: addition refined honey amount is 0.2 times of medicated powder quality) of quality.
9. the preparation method of the powder of the preparation as described in claim 1-2 is arbitrary, it is characterised in that step is as follows:
(1) take Folium Perillae, Caulis et Folium Arctii, Flos Lilii viriduli and Citrus aurantium L. var. amara Engl. to clean, add soda water moistening 18-28 minute (preferably: vexed
Moisten 20-26 minute；More preferably: moistening 23 minutes), taking out, slow fire is fried to being dried and pulverizing；
(2) Caulis Cucurbitae and dish remove impurity being cleaned, cut into chunks, be placed in frying pan, slow fire stir-fries 6-12 minute (preferably: literary composition
Fire stir-fries 9 minutes), taking-up is pulverized, and drenches and mixes 15 minutes into saline solution, then under the conditions of being placed in 45 DEG C, freeze-day with constant temperature；
(3) take Radix Elaeagni, Radix Tylophorae Yunnanensis, Radix Symplocoris Caudatae and Radix Fici beecheyanae to clean, be placed in washing water of rice and infiltrate 20-36 minute (preferably
: infiltrate 24-32 minute；More preferably: infiltrate 28 minutes), taking out section, drenching into concentration is the white vinegar of 10%, and constant temperature dries
Dry；
(4) Semen Phaseoli and Concha Arcae (forging) are placed in marmite, add the water of boiled crude drug quality 8-12 times (preferably: add
Enter the water of boiled crude drug quality 10 times), big fire decocts to boiling, adds Herba Psiloti Nudi, Herba Tricyrtis Pilosae and Herba Agrimoniae, changes little fire and continue
Continuous decoction 35 minutes, is collected by filtration filtrate, and filtering residue adds water and again decocts, and merges twice gained filtrate；
(5) heating concentration step (4) gained filtrate, pulverizes and sieves after drying together with step (1) (2) (3) made crude drug, system
Become medicated powder, obtain powder.
10. the preparation method of preparation powder as claimed in claim 9, it is characterised in that step (5) pulverized 200-280 mesh
Sieve is (preferably: pulverized 220-260 mesh sieve；More preferably: pulverized 240 mesh sieves).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610267780.5A CN105770381A (en) | 2016-04-27 | 2016-04-27 | Preparation taken by patients suffering from gastric ulcers and production method of preparation |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610267780.5A CN105770381A (en) | 2016-04-27 | 2016-04-27 | Preparation taken by patients suffering from gastric ulcers and production method of preparation |
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| Publication Number | Publication Date |
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| CN105770381A true CN105770381A (en) | 2016-07-20 |
Family
ID=56398635
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|---|---|---|---|
| CN201610267780.5A Withdrawn CN105770381A (en) | 2016-04-27 | 2016-04-27 | Preparation taken by patients suffering from gastric ulcers and production method of preparation |
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| Country | Link |
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Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105327296A (en) * | 2015-12-12 | 2016-02-17 | 徐士杰 | Medicine for treating peptic ulcer and preparing method of medicine |
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2016
- 2016-04-27 CN CN201610267780.5A patent/CN105770381A/en not_active Withdrawn
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105327296A (en) * | 2015-12-12 | 2016-02-17 | 徐士杰 | Medicine for treating peptic ulcer and preparing method of medicine |
Non-Patent Citations (1)
| Title |
|---|
| 张兆辉: "由消化性溃疡相关文献探讨中医治疗与处方用药规律", 《中国博士学位论文全文数据库(电子期刊)》 * |
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Address after: 810000, building 3, No. 361, Qilian Road, Chengbei District, Qinghai, Xining 1-302 Applicant after: Zhang Guichen Address before: 250000 No. 23, Hualong Road, Licheng District, Shandong, Ji'nan Applicant before: Zhang Guichen |
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