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CN105534815B - A kind of skin care compositions and preparation method thereof containing lotus active constituent - Google Patents

A kind of skin care compositions and preparation method thereof containing lotus active constituent Download PDF

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Publication number
CN105534815B
CN105534815B CN201610037899.3A CN201610037899A CN105534815B CN 105534815 B CN105534815 B CN 105534815B CN 201610037899 A CN201610037899 A CN 201610037899A CN 105534815 B CN105534815 B CN 105534815B
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parts
skin
silicone polymer
lotus
dimethyl silicone
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CN105534815A (en
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张�雄
成晓松
梁永琰
陈玉兰
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CHONGQING PUPU BIOTECHNOLOGY Co Ltd
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CHONGQING PUPU BIOTECHNOLOGY Co Ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/92Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
    • A61K8/927Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of insects, e.g. shellac
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/19Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/19Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
    • A61K8/29Titanium; Compounds thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/494Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with more than one nitrogen as the only hetero atom
    • A61K8/4946Imidazoles or their condensed derivatives, e.g. benzimidazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73Polysaccharides
    • A61K8/735Mucopolysaccharides, e.g. hyaluronic acid; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/84Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions otherwise than those involving only carbon-carbon unsaturated bonds
    • A61K8/89Polysiloxanes
    • A61K8/891Polysiloxanes saturated, e.g. dimethicone, phenyl trimethicone, C24-C28 methicone or stearyl dimethicone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/84Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions otherwise than those involving only carbon-carbon unsaturated bonds
    • A61K8/89Polysiloxanes
    • A61K8/891Polysiloxanes saturated, e.g. dimethicone, phenyl trimethicone, C24-C28 methicone or stearyl dimethicone
    • A61K8/893Polysiloxanes saturated, e.g. dimethicone, phenyl trimethicone, C24-C28 methicone or stearyl dimethicone modified by an alkoxy or aryloxy group, e.g. behenoxy dimethicone or stearoxy dimethicone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q1/00Make-up preparations; Body powders; Preparations for removing make-up
    • A61Q1/02Preparations containing skin colorants, e.g. pigments
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/02Preparations for care of the skin for chemically bleaching or whitening the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/08Anti-ageing preparations
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/42Colour properties
    • A61K2800/43Pigments; Dyes
    • A61K2800/432Direct dyes

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
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  • Dermatology (AREA)
  • Chemical & Material Sciences (AREA)
  • Inorganic Chemistry (AREA)
  • Insects & Arthropods (AREA)
  • Zoology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Gerontology & Geriatric Medicine (AREA)
  • Cosmetics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

The present invention provides a kind of skin care compositions and preparation method thereof containing lotus active constituent,The ingredient of the skin care compositions includes glycerine,1,3 butanediols,Saualane,Dimethyl silicone polymer,Modified dimethyl polysiloxane,Carbonic acid dioctyl ester,Isopropyl myristate,Cetostearyl alcohol,Cera alba,Titanium dioxide,Iron oxides,Sodium chloride,Nuciferine,Lotus pollen,Allantoin,Sodium Hyaluronate,Methyl hydroxybenzoate,Nipasol,Bi-imidazolidinyl urea,Iron oxide red,Iron oxide yellow,Essence,Deionized water,Powder of the present invention makes full use of the active ingredient of lotus,The classification and its dosage of each ingredient of reasonable disposition,Using rational preparation method,The colour of skin of the color of skin care item obtained close to human body,Aberration is not will produce after being applied to skin surface,And significantly improve the moisturizing degree of skin,Reduce the transdermal percentage of water loss of skin,Improve skin elasticity.

Description

A kind of skin care compositions and preparation method thereof containing lotus active constituent
Technical field
The present invention relates to skin care fields, more particularly to a kind of skin care compositions and its system containing lotus active constituent Preparation Method.
Background technology
Lotus is called lotus flower, is the perennial root water plant of Nymphaeceae Nelumbo, and lotus perennation is draft in water Plant, rhizome is initially tiny such as finger, tool it is horizontal walk root-like stock, i.e. our daily lotus rhizomes eaten.Leaf is round, is higher by the water surface, there is length Petiole, tool thorn, grows at peltate.Flower Dan Sheng is in bennet top, 10~20 centimetres of diameter;Sepal is caducous;Petal majority be it is red, Pink or white;Majority is stamen;Lotus nut skin is more, and from life, embedding life is in spongy holder cave.Its nut it is oval or It is oval, it is commonly called as lotus seeds.
Lotus whole body is precious, and lotus root, leaf, petiole, lotus stamen, lotus pod (holder) can be used as medicine, can clearing away heat to stop bleeding;Lotus nut be (seed Embryo) there are clearing away the heart-fire, cardiac stimulant antihypertensive effect;Lotus seeds (nut) have tonifying spleen and stopping diarrhea, relieving mental strain and strengthening the kidney effect.Lotus rhizome can for vegetable consumption or Extract starch (lotus root starch).Lotus original refers to its fruit, is commonly called as the seedpod of the lotus;Flower, fruit are all loosely referred to as lotus, and rhizomatous loose part claims Lotus root.
The warm-natured bitter but sweet flavor of lotus, can be promoting blood circulation and removing blood stasis, and relieving summer-heat goes heat toxin, can be used for treating traumatic injury, and lotus, which also has, dispels The wet effect of weathering can be used for treating wet sore mange, and it is broken that when use takes lotus to rub, and it is effective to be affixed on red and swollen affected part.According to《Herbal guiding principle Mesh》It carries:Lotus energy relieving palpitation QI invigorating, takes lotus to cook congee with glutinous rice, then QI invigorating, which is preserved youthful looks, makes light of one's life by commiting suicide.Tao Hongjing cloud:" lotus flower relieving palpitation benefit color, It preserves youthful looks and makes light of one's life by commiting suicide.”
In the prior art there are no the active constituent of lotus to be applied in skin care compositions, more without corresponding producer Method.
Invention content
In view of the foregoing deficiencies of prior art, the purpose of the present invention is to provide a kind of containing lotus active constituent Skin care compositions and preparation method thereof, it is poor to the moisture retention of skin for solving skin care item in the prior art, use rear skin The problems such as lacking flexibility.
In order to achieve the above objects and other related objects, the present invention provide first aspect provide it is a kind of containing lotus activity at Divide skin care compositions, includes the component of following parts by weight:
0-10 parts of glycerine, 0.05-5 parts of saualane, 0.1-10 parts of dimethyl silicone polymer, changes 0-10 parts of 1,3-BDO 0.1-10 parts of dimethyl silicone polymer of property, 0-10 parts of carbonic acid dioctyl ester, 0-5 parts of isopropyl myristate, cetostearyl alcohol 0.1-5 Part, 0.1-5 parts of cera alba, 0.1-5 parts of sodium chloride, 0.05-5 parts of Nuciferine, 0.1-10 parts of lotus pollen, 0.1-5 parts of allantoin, 0.01-2 parts of Sodium Hyaluronate, 0.05-0.5 parts of methyl hydroxybenzoate, 0.05-0.5 parts of Nipasol, 0.1-1 parts of bi-imidazolidinyl urea, 0.05-1 parts of essence, 20-90 parts of deionized water.
Further, include the component of following parts by weight:
2-6 parts of glycerine, 3-8 parts of 1,3-BDO, 1-4 parts of saualane, 4-8 parts of dimethyl silicone polymer, modified poly- diformazan 3-8 parts of radical siloxane, 0.1-8 parts of carbonic acid dioctyl ester, 1-4 parts of isopropyl myristate, 1-4 parts of cetostearyl alcohol, cera alba 1-4 Part, 1-4 parts of sodium chloride, 0.5-2 parts of Nuciferine, 1-8 parts of lotus pollen, 0.5-2 parts of allantoin, 0.1-1.5 parts of Sodium Hyaluronate, 0.3-0.4 parts of methyl hydroxybenzoate, 0.15-0.3 parts of Nipasol, 0.4-0.6 parts of bi-imidazolidinyl urea, 0.2-0.5 parts of essence, go from Sub- water 30-85 parts.
Further, further include the component for there are following parts by weight:0.1-3 parts of titanium dioxide, 0.05-0.2 parts of iron oxides, 0.05-0.2 parts of iron oxide red, 0.05-0.2 parts of iron oxide yellow.
Further, further include the component for there are following parts by weight:0.5-2.5 parts of titanium dioxide, iron oxides 0.1-0.2 Part, 0.1-0.2 parts of iron oxide red, 0.1-0.2 parts of iron oxide yellow.
Wherein, INCI (name of international cosmetic raw material) entitled IRON OXIDES of iron oxides are (referring to state food Pharmaceuticals administration general bureau issued on June 30th, 2014《Cosmetic material Names Catalogue is used》), color is black Color also known as iron oxide black.
Further, the dimethyl silicone polymer is low viscosity dimethyl silicone polymer or low viscosity poly dimethyl silicon The mixture of the dimethyl silicone polymer of oxygen alkane and hyperviscosity, the viscosity of the low viscosity dimethyl silicone polymer≤ 50mPa·s;The dimethyl silicone polymer viscosity > 200,000,00mPas of the hyperviscosity, low viscosity poly dimethyl silicon When oxygen alkane is mixed with the dimethyl silicone polymer of hyperviscosity, the weight of low viscosity dimethyl silicone polymer accounts for the two total weight Percentage is 75%-90%.
Further, the modified group of the modified dimethyl polysiloxane is the mixing of polyethers, alkyl or the two, i.e., The mixing of one or both of specially polyether-modified dimethyl silicone polymer, alkyl-modified dimethyl silicone polymer.
Further, the modified polyether group of the polyether-modified dimethyl silicone polymer is ethylene oxide, epoxy third The mixing of alkane or the two.
Further, the total moles of the modified group on the polyether-modified dimethyl silicone polymer are 1-30.
Further, the carbochain of the modified alkyl group of the alkyl-modified dimethyl silicone polymer is straight chain, described The number of carbon is 10-20 in the carbochain of modified alkyl group.
Further, the molecular weight of the Sodium Hyaluronate is 800,000 to 2,000,000.
Further, the essence is daily essence, and the INCI (name of international cosmetic raw material) of daily essence is entitled FRAGRANCE (is issued referring to state food pharmaceuticals administration general bureau on June 30th, 2014《Cosmetic material is used Names Catalogue》).
Second aspect of the present invention provides the preparation method of above-mentioned skin care compositions, includes the following steps:
1) sodium chloride, glycerine, 1,3-BDO, allantoin are weighed respectively by formula, mix, appropriate deionization is added Water, being sufficiently stirred makes it be uniformly dispersed, heating, spare as A phases;
2) by formula, to weigh the saualane, dimethyl silicone polymer, modified dimethyl polysiloxane, carbonic acid two respectively pungent Ester, isopropyl myristate, cetostearyl alcohol, cera alba, methyl hydroxybenzoate, Nipasol, mixing, being sufficiently stirred keeps its dispersion equal Even, heating is spare as B phases;
3) Sodium Hyaluronate, Nuciferine, lotus pollen are weighed respectively by formula, then use appropriate amount of deionized water molten respectively Solution, it is spare;
4) B phases reserve liquid made from step 2) is mixed with A phases reserve liquid obtained in step 1), stirs 30min or more, Mixing carries out first time cooling, then titanium dioxide, iron oxides, iron oxide red, iron oxide yellow and surplus is added by formula ratio Deionized water stirs 30min or more, mixing;It carries out second to cool down, adds Sodium Hyaluronate made from step 3), lotus leaf Alkali, lotus pollen aqueous solution stir 30min or more, mixing;Carry out third time cooling, by formula ratio addition bi-imidazolidinyl urea, Essence stirs 30min or more, mixing, finished product.
Further, it is both heated to 75-85 DEG C in the step 1) and step 2), on the one hand which is conducive to each component Dissolving, on the other hand component will not be caused to fail because of high temperature;The dosage of deionized water is respectively corresponding in step 3) One times or more of bright matter acid sodium, Nuciferine, lotus pollen weight, which is conducive to the dissolving of solute;Step 4) Middle first time is cooled to 70-75 DEG C, which is conducive to the dissolving of four kinds of colorants, while colorant will not be due to high temperature Failure, is cooled to 45-50 DEG C for the second time, since Sodium Hyaluronate, Nuciferine, lotus pollen are easy inactivation at high temperature, The temperature range not only improves the dissolving of Sodium Hyaluronate, Nuciferine, lotus pollen, while effectively avoiding these three compositions because of height Temperature and inactivate, be cooled to 35-40 DEG C for the third time, which not only improves the dissolving of bi-imidazolidinyl urea, essence, meanwhile, It effectively avoids preservative bi-imidazolidinyl urea from inactivating, also effectively reduces the volatilization of essence.
As described above, the skin care compositions and preparation method thereof containing lotus active constituent of the present invention, has with following Beneficial effect:
Nuciferine is a kind of aporphine alkaloids contained in lotus leaf, is the main Lipid-lowering activities ingredient in lotus leaf;Lotus Leaf alkali is to shine the lotus leaf of dry grinding as raw material, using cellulase pretreatment, dilute hydrochloric acid extraction, ultrasonic wave assisted extraction, chloroform Extraction serial of methods is extracted, and purity is 98% (i.e. mass fraction).Nuciferine is active tune in inventive formulation Manage agent.
Lotus pollen be honeybee acquisition lotus essence, specially honeybee acquisition lotus pollen, then through honeybee processing and At pollen dough.Its main dietotherapy ingredient is:Protein, amino acid, vitamin, trace element, organized enzyme, flavonoids Close object, lipid, nucleic acid, brassin, phytic acid etc..Wherein amino acid content and ratio are closest to FAO (Food and Agriculture Organization of the United Nation) (FAO) The amino acid pattern of recommendation, this is extremely rare in wholefood.Lotus pollen is rich in protein, amino acid, and content is more than 5-7 times of egg, milk is referred to as in " concentrated nutrition library " in nutrition.It is people that unsaturated fatty acid in pollen, which has several, The essential fatty acid that body cannot synthesize.It is also simultaneously a kind of concentrate of natural complex, content is very high, and B family vitamin is abundant, And there is the element of obvious effect also compared with horn of plenty human body beauty treatment.Lotus pollen adjusts endocrine, can promote endocrinal glands Development, improve the secreting function of body of gland.It neutralizes a toxin, adjusts internal circulation system, restore and maintain body normal function;Beauty treatment Beauty, anti-aging.Lotus pollen is not only conducive to human consumption and absorbs, and can be also directly absorbed and utilized for skin.Lotus pollen energy Improve the nutritional status of Skin Cell, boost metabolism, delay cell senescence, increases skin elasticity, smooth away wrinkles, make skin Soft health, smooth exquisiteness, skin whitening eliminate various spots, reduce wrinkle.For oral administration or external application lotus pollen can promote new old Metabolism improves nutrition condition, enhances the vigor of skin and the resistance to extraneous poor environment.Lotus pollen is in inventive formulation In be active additive, lotus pollen is a group under Bee Pollen, and the lotus pollen in the present invention is a kind of commercially available edible High-quality Bee Pollen product, index meet《Bee Pollen》(GB/T30359-2013).
Glycerine:That is glycerine is colourless sweet clear and bright thick liquid.It is odorless, there is warm sweet taste, is commonly called as glycerine, it can be from air Middle absorption moisture.Relative density 1.26362,17.8 DEG C of fusing point, boiling point 290.0 DEG C (decomposition), index of refraction 1.4746, flash-point (is opened Cup) 176 DEG C, acute toxicity:LD50:29600mg/kg (rat oral);23500mg/kg (mouse oral).It can be used as solvent, Lubricant, medicament and sweetener.Glycerine is used as moisturizer in the present invention.
1,3-BDO:1,3-BDO has the characteristics that the reactive, odorless, less toxic of dihydric alcohol, good water solubility.At this Moisturizer is used as in invention.In terms of moisturizing, since 1,3-BDO is small molecule moisturizing composition, so water ratio very little is grabbed, Also there is certain bacteriostasis simultaneously.The safety of 1,3-BDO is higher, experiments have shown that, interruption smearing is being carried out to human body When, it is primary every other day to smear, totally 16 days, in all 200 people for participating in experiment, all find no any irritating inflammation Disease.About the irritation to eye mucous membrane, once there is researcher to be tested with white mouse, obtained result is still safety very It is high.Researcher is added into the oral cavity experiment that surrounding is carried out in toothpaste, as a result, it is also nonirritant to mucous membrane of mouth, is one The very high composition of kind safety.
Saualane (Squalane):Molecular formula C30H62, being that the squalene that is extracted from hydrogenated hydro carbons grease is hydrogenated is made A kind of squalene extracting haveing excellent performance, it is also known as eepwater shark liver oils.Scientific research finds that saualane is rare chemical stabilization Property it is high, the splendid animal fat of use feeling has preferable compatibility to skin, will not cause allergy and stimulation, and can accelerate to match Other active components are permeated into skin in side;With lower polarity and medium spreadability, and pure, colourless, free from extraneous odour; It may also suppress the growth of mould.Saualane can reinforce maintenance epidermis, be effectively formed natural protective film, help between skin and sebum Balance.Saualane is a kind of lipid closest to human sebaceous, and affinity is strong, and it is one that can melt with the sebum film of mankind itself Body forms one layer of natural barrier in skin surface.Saualane can also inhibit the peroxidating of skin lipid, can effectively infiltrate through flesh Skin, and promote the proliferation of skin base cell, to delay skin aging, improving and eliminating chloasma has apparent physiology to imitate Fruit.Saualane can also be such that skin pore opens, and promote blood microcirculation, promote the metabolism of cell, and help is repaired damaged thin Born of the same parents.Saualane is used as emollient in the present invention.
Dimethyl silicone polymer (Polydimethylsiloxane, PDMS):Also referred to as dimethicone, as a kind of high Molecule organo-silicon compound have optical clear, and under normal circumstances, it is considered to be inertia, it is nontoxic, and it is nonflammable.Poly- diformazan Radical siloxane is a kind of organic silicon materials of hydrophilic class, and there are many derivatives for it, are applied to drug, daily chemical product, food etc. Various aspects are also applied to the cosmetics and skincare products such as cosmetics, shampoo, shower cream, lipstick, the sunblock lotion of lotion or creme In.Dimethyl silicone polymer is emollient in the present invention.Dimethyl silicone polymer in the present invention is low viscosity poly dimethyl The mixture of siloxanes or the dimethyl silicone polymer of low viscosity dimethyl silicone polymer and hyperviscosity, the low viscosity are poly- Viscosity≤50mPas of dimethyl siloxane;The dimethyl silicone polymer viscosity > 200,000 of the hyperviscosity, 00mPa·s。
Modified dimethyl polysiloxane refers to the part methyl group that certain organic groups replace dimethyl silicone polymer, with It improves certain performance of dimethyl silicone polymer and adapts to a variety of different purposes.Modified dimethyl polysiloxane is in the present invention As emulsifier.The modified group of modified dimethyl polysiloxane is preferably the mixing of alkyl, polyethers or the two in the present invention, It can be described poly- with the mixing for one or both of alkyl dimethyl polysiloxanes, polyether-modified dimethyl silicone polymer The modified polyether group of ether modified dimethyl polysiloxane is preferably the mixing of ethylene oxide, propylene oxide or the two, polyethers The total moles of modified group on modified dimethyl polysiloxane are preferably 1-30;The modification of alkyl-dimethyl based polysiloxane Alkyl group is straight chain, and the number of carbon is preferably 10-20 in carbochain.In existing commercially available product, it is specifically as follows Japanese SHIN-ETSU HANTOTAI The KF-6017 of company, DC 5200, the DC 5324 of Dow Corning Corporation, Germany win the ABIL EM of wound Degussa-Gao Shi meter Te 90, ABIL EM 180 etc..
Carbonic acid dioctyl ester:Its appearance is limpid colourless liquid, almost odorlessness, and cloud point is less than 20 DEG C, molecular weight about 286g/ Mol, characteristic are as follows:1, high dispersion rate, reaches 1600mm2/10min;2, the skin sense for exquisiteness of feeling well, good permeability are similar Volatile silicone oils;3, grease, resistance to oxidation, hydrolysis are saturated;4, low polarity, is easily emulsified;5, vegetable fat source, biology drop Solution, irritation are low;6, there is very high solubility to crystalloid sun-screening agent, the sun-proof ability of product can be improved;7, to titanium dioxide, Zinc oxide has good dispersibility, is suitble to prepare foundation cream;8, there is good makeup removing effect to color make-up;9, anti-sweat product can be eliminated Albinism.Its application range:Skin care item, sunscreen product, foundation cream, anti-sweat agent, clean skin product.Carbonic acid dioctyl ester is a kind of novel Emollient, it have extremely dry and comfortable skin sense and good spreadability, can compare favourably with volatile silicone oils;Meanwhile it to crystallization Type Orangic sunscreen and titanium dioxide, zinc oxide have fine dissolubility, and the sun-proof of product is remarkably improved in sunscreen product Coefficient (spf value) and the greasy feeling for lowering sun-screening agent.As a kind of grease of plant origin, carbonic acid dioctyl ester has splendid skin Skin compatibility, it is very low to the irritation of skin and mucous membrane, it is highly suitable for infant's product and high-grade skin care item.Carbonic acid dioctyl ester It is skin conditioning agent in the present invention.
Isopropyl myristate:Alias is isopropyl myristate, isopropyl myristate, is the liquid of colorless and odorless, can be with It is mixed and is transparent with arbitrary proportion with vegetable oil, not facile hydrolysis and rancid.The component plays the role of moisturizing and skin care, Skin is preferable to the absorbability of this product, can effectively be contacted with hair follicle in cortex, penetrates into cortex depths, and by the work in cosmetics Property component is brought into, and the effect of active ingredient is given full play to.It is used as cosmetic solvents, skin moisturizer, bleeding agent, used also as The dispersant of lipstick, hair cream, lipstick, cleaning frost, face powder and medical cream, can also make perfume fixastive.This composition is medium-to-high grade One of important addition composition of cosmetics, to skin have it is fabulous permeate, moisten and emollescence, be used as the emulsifier of cosmetics And wetting agent.Isopropyl myristate is skin conditioning agent in the present invention.
Cetostearyl alcohol:Trade name is cetostearyl alcohol cetostearyl alcohol, and white crystalline solid is particle or wax stone Shape, savory, relative density d is 4500.8176, and refractive index n (D) is 391.4283,48~50 DEG C of fusing point, 344 DEG C of boiling point.No It is dissolved in water, is dissolved in ethyl alcohol, ether, chloroform and mineral oil.Suitable for all kinds of cosmetics, as matrix, particularly suitable for cream And lotion.Cetostearyl alcohol rises in the present invention assigns fat, conditioning, thickening power.
Cera alba:Cera alba is to be refined by beeswax (wax that honeybee secrets out of) oxidation bleaching and obtained, and is white or faint yellow Solid, matt, nodeless mesh, 62~67 DEG C of fusing point, relative density:0.954~0.964, (75 DEG C) of index of refraction is 1.4410- 1.4430;Acid value is 5.0~8.0 (middle beeswaxs) or 16.0~23.0 (western beeswaxs);Saponification number is 85~100;Iodine number is 8.0- 13.0;Can be used for increasing the consistency of emulsifiable paste and ointment, stablize water-in-oil emulsion etc..Cera alba is emulsifier in the present invention, Cera alba can be the arbitrary mixing of one or both of middle beeswax, western beeswax in the present invention.
Titanium dioxide, iron oxides, iron oxide red, iron oxide yellow are colorant, and the code name of iron oxide red is The code name of CI77491, iron oxide yellow are CI77492.
Sodium chloride:Additive is used as auxiliary additive in the present invention.
Allantoin:Alias Allantoin, Allantoin, Allantion, Allantoin are a kind of second Interior ureide derivative.Classification system is Allantoin, and No. CAS is 97-59-6, is made as Material synthesis using glyoxalic acid, urea. Allantoin is white powder, and free from extraneous odour, purity is 98.6%-100% (mass fraction);Skin can be made to keep moisture content, and then made Skin keeps moist and soft.Allantoin sterling is a kind of nontoxic, tasteless and nonirritant, without hypersensitive white crystal, in water Crystallization is single prism or colorless crystalline powder;Hot water, hot alcohol and diluted sodium hydroxide solution can be dissolved in;It is slightly soluble in the water of room temperature And alcohol, it is insoluble in the organic solvents such as ether and chloroform;Its saturated aqueous solution (a concentration of 0.6wt%) is in subacidity;PH is 5.5. Stablize in the aqueous solution that pH value is 4-9, also stablize in nonaqueous solvents and dry air, is boiled in strong alkali solution and day Decomposable asymmetric choice net under light exposure, molecular weight:158.12, fusing point:226-240 DEG C, loss on drying (%)≤1.0, ignition residue (%)≤ 0.1, heavy metal (in terms of pb)≤10ppm.Allantoin is skin conditioning agent in the present invention.
Essence:Specially daily essence is in the present invention odorant.
Methyl hydroxybenzoate, Nipasol, bi-imidazolidinyl urea are preservative in the present invention.
Sodium Hyaluronate:Hyaluronic acid (Hyaluronic Acid, abbreviation HA) is glucuronic acid and N-acetylamino The straight chain polymer mucopolysaccharide that the disaccharide repetitive unit of glucose connects and composes, Sodium Hyaluronate (SODIUM HYALURONATE) For the substance extracted from cockscomb, it can also be fermented and be made by Lactococcus, the hyaluronic acid as commodity is generally its sodium salt, That is Sodium Hyaluronate (Sodium Hyaluronate), traditionally still referred to as hyaluronic acid.Sodium Hyaluronate is emerging both at home and abroad Advanced bio product, molecular weight be it is tens of thousands of to millions of, aqueous solution with high moisture retention, viscoplasticity and lubricity, It is the bio-molecules being widely present in skin and other tissues, there is fabulous moisture-keeping function, is known as ideal in the world Natural moisturizing factor (Natural MolsturlZlng Factor, NMF).It is the cosmetics found in current nature With the best substance of performance of keeping humidity.Hyaluronic acid acts on skin surface, and macromolecular Sodium Hyaluronate can be formed in skin surface One layer of ventilative film, makes skin smooth moisten, and can obstruct the intrusion of alien bacteria, dust, ultraviolet light, protects the skin from Infringement;Micromolecule hyaluronic acid sodium can penetrate into corium, have mild dilation capillary, increase blood circulation, improve intermediate generation It thanks, promote skin-nourishing absorption, have the function of stronger wrinkle-chasing, skin elasticity, delay skin aging can be increased.Hyalomitome Acid can also promote the proliferation and differentiation, scavenging activated oxygen of epidermal cell, can prevent and repair skin injury.The water of hyaluronic acid Solution has very high viscosity, water phase can be made to thicken, and the lotion uniform and smooth after being emulsified with oil phase has stable emulsion effect. Hyaluronic acid is the best natural moisture preserving ingredient of the cosmetics of super quality, and compatibility is good, and the additive amount in cosmetics is generally 0.05- 0.5wt%.This product is white or off-white color particle or powder, odorless, when dry, nitrogen content 2.8wt%-4.0wt%, and Portugal Glucuronic acid content is 37.0wt%-51.0wt%;The efficient water lock moisturizer of toiletries and skin repair group are promoted sun-proof The sun protection factor (spf value) of product assigns product water and moistens soft skin sense;With the skin that compacts, permanent moisturizing, prevent dehydration, The effects that promoting histocyte regeneration.Sodium Hyaluronate is moisture-regulating agent in the present invention.Hyalomitome of the present invention For sour sodium molecule amount 800,000 to 2,000,000, specific targets are as follows:
Index subjet Index request
Appearance White or off-white color particle or powder
Smell It is odorless
PH value (0.5%) 6.0-7.5
Sodium Hyaluronate >=92.0wt%
Glucuronic acid >=44.0wt%
Heavy metal ≤20ppm
Loss on drying ≤ 8.0%
Protein content ≤ 0.041%
Total number of bacteria <10CFU/g
Mould and saccharomycete sum <10CFU/g
Staphylococcus aureus It must not detect
Pseudomonas aeruginosa It must not detect
Skin care compositions of the present invention makes full use of the active ingredient of lotus, the classification and its dosage of each ingredient of reasonable disposition, Preparation method reaches most fast solution rate, the skincare composition under the premise of fully considering the highest heating temperature of each component Object have moisturizing, whitening, increase skin elasticity, persistently increase skin vigor, resist environmental pollution, delay skin aging effect The color of obtained skin care item after four kinds of titanium dioxide, iron oxides, iron oxide red, iron oxide yellow colorants is added in fruit Close to the color of Asia yellow race application on human skin, aberration is not will produce after being applied to skin surface, and significantly improve the moisturizing of skin Degree reduces the transdermal percentage of water loss of skin, improves skin elasticity.
Specific implementation mode
Illustrate that embodiments of the present invention, those skilled in the art can be by this specification below by way of specific specific example Disclosed content understands other advantages and effect of the present invention easily.The present invention can also pass through in addition different specific realities The mode of applying is embodied or practiced, the various details in this specification can also be based on different viewpoints with application, without departing from Various modifications or alterations are carried out under the spirit of the present invention.
Embodiment 1
A kind of skin care compositions containing lotus active constituent, includes the component of following parts by weight:
10 parts of glycerine, 10 parts of 1,3-BDO, 5 parts of saualane, 0.1 part of dimethyl silicone polymer, modified polydimethyl silicon 10 parts of oxygen alkane, 5 parts of isopropyl myristate, 5 parts of cetostearyl alcohol, 0.1 part of cera alba, 1.2 parts of titanium dioxide, iron oxides 0.05 part, 5 parts of sodium chloride, 5 parts of Nuciferine, 10 parts of lotus pollen, 5 parts of allantoin, 2 parts of Sodium Hyaluronate, methyl hydroxybenzoate 0.5 Part, 0.5 part of Nipasol, 1 part of bi-imidazolidinyl urea, 0.05 part of iron oxide red, 0.05 part of iron oxide yellow, 0.5 part of daily essence, 25 parts of deionized water.
The modified dimethyl polysiloxane of the present embodiment uses the KF-6017 emulsifiers of Japan XINYUE.
The preparation method of above-mentioned skin care compositions includes the following steps:
1) weigh appropriate amount of deionized water and preheat, then by formula weigh respectively the sodium chloride, glycerine, 1,3-BDO, Allantoin is put into clean emulsification pot, and mixing is added in the deionized water of preheating, and being sufficiently stirred makes it be uniformly dispersed, heating It is spare as A phases to 75 DEG C;
2) saualane, dimethyl silicone polymer, modified dimethyl polysiloxane, myristic acid are weighed respectively by formula Isopropyl ester, cetostearyl alcohol, cera alba, methyl hydroxybenzoate, Nipasol are put into clean oil cauldron, and mixing, being sufficiently stirred makes it It is uniformly dispersed, is heated to 75 DEG C, it is spare as B phases;
3) Sodium Hyaluronate, Nuciferine, lotus pollen are weighed respectively by formula, then one times or more weight is respectively added Deionized water dissolving, it is spare;
4) B phases reserve liquid made from step 2) is mixed with A phases reserve liquid obtained in step 1), stirs 30min or more, Mixing carries out first time cooling, is cooled to 75 DEG C, then titanium dioxide, iron oxides, iron oxide red, oxidation is added by formula ratio Iron oxide yellow and balance deionized water stir 30min or more, mixing;It carries out second to cool down, is cooled to 50 DEG C, adds step 3) Sodium Hyaluronate made from, Nuciferine, lotus pollen aqueous solution stir 30min or more, mixing;Carry out third time cooling, drop Bi-imidazolidinyl urea, daily essence is added to 40 DEG C, by formula ratio in temperature, stirs 30min or more, mixing, finished product.
Embodiment 2
A kind of skin care compositions containing lotus active constituent, includes the component of following parts by weight:
10 parts of glycerine, 0.05 part of saualane, 10 parts of dimethyl silicone polymer, 0.1 part of modified dimethyl polysiloxane, carbonic acid 0.1 part of dioctyl ester, 4 parts of cetostearyl alcohol, 4 parts of cera alba, 2.5 parts of titanium dioxide, 0.05 part of iron oxides, 0.1 part of sodium chloride, 0.05 part of Nuciferine, 0.1 part of lotus pollen, 0.1 part of allantoin, 0.01 part of Sodium Hyaluronate, 0.05 part of methyl hydroxybenzoate, oxybenzene third 0.05 part of ester, 0.1 part of bi-imidazolidinyl urea, 0.05 part of iron oxide red, 0.05 part of iron oxide yellow, 1 part of daily essence, deionized water 63 parts.
The modified dimethyl polysiloxane of the present embodiment uses the DC 5200 of Dow Corning Corporation.
The preparation method of above-mentioned skin care compositions includes the following steps:
1) it weighs appropriate amount of deionized water and preheats, then the sodium chloride, glycerine, allantoin are weighed respectively by formula, put into In clean emulsification pot, mixing is added in the deionized water of preheating, and being sufficiently stirred makes it be uniformly dispersed, and is heated to 77 DEG C, as A phases, it is spare;
2) by formula, to weigh the saualane, dimethyl silicone polymer, modified dimethyl polysiloxane, carbonic acid two respectively pungent Ester, cetostearyl alcohol, cera alba, methyl hydroxybenzoate, Nipasol are put into clean oil cauldron, and mixing, being sufficiently stirred makes its dispersion Uniformly, 77 DEG C are heated to, it is spare as B phases;
3) Sodium Hyaluronate, Nuciferine, lotus pollen are weighed respectively by formula, then one times or more weight is respectively added Deionized water dissolving, it is spare;
4) B phases reserve liquid made from step 2) is mixed with A phases reserve liquid obtained in step 1), stirs 30min or more, Mixing carries out first time cooling, is cooled to 74 DEG C, then titanium dioxide, iron oxides, iron oxide red, oxidation is added by formula ratio Iron oxide yellow and balance deionized water stir 30min or more, mixing;It carries out second to cool down, is cooled to 49 DEG C, adds step 3) Sodium Hyaluronate made from, Nuciferine, lotus pollen aqueous solution stir 30min or more, mixing;Carry out third time cooling, drop Bi-imidazolidinyl urea, daily essence is added to 39 DEG C, by formula ratio in temperature, stirs 30min or more, mixing, finished product.
Embodiment 3
A kind of skin care compositions containing lotus active constituent, includes the component of following parts by weight:
10 parts of 1,3-BDO, 1 part of saualane, 8 parts of dimethyl silicone polymer, 8 parts of modified dimethyl polysiloxane, carbonic acid 10 parts of dioctyl ester, 1 part of isopropyl myristate, 0.1 part of cetostearyl alcohol, 5 parts of cera alba, 0.1 part of titanium dioxide, iron oxides 0.1 part, 1 part of sodium chloride, 0.5 part of Nuciferine, 1 part of lotus pollen, 0.5 part of allantoin, 0.1 part of Sodium Hyaluronate, methyl hydroxybenzoate 0.4 part, 0.2 part of Nipasol, 0.5 part of bi-imidazolidinyl urea, 0.1 part of iron oxide red, 0.1 part of iron oxide yellow, daily essence 0.05 part, 52 parts of deionized water.
The modified dimethyl polysiloxane of the present embodiment uses the DC 5324 of Dow Corning Corporation.
The preparation method of above-mentioned skin care compositions includes the following steps:
1) it weighs appropriate amount of deionized water and preheats, then the sodium chloride, 1,3-BDO, allantois are weighed respectively by formula Element is put into clean emulsification pot, and mixing is added in the deionized water of preheating, being sufficiently stirred makes it be uniformly dispersed, and is heated to 80 DEG C, it is spare as A phases;
2) by formula, to weigh the saualane, dimethyl silicone polymer, modified dimethyl polysiloxane, carbonic acid two respectively pungent Ester, isopropyl myristate, cetostearyl alcohol, cera alba, methyl hydroxybenzoate, Nipasol are put into clean oil cauldron, mixing, Being sufficiently stirred makes it be uniformly dispersed, and is heated to 80 DEG C, spare as B phases;
3) Sodium Hyaluronate, Nuciferine, lotus pollen are weighed respectively by formula, then one times or more weight is respectively added Deionized water dissolving, it is spare;
4) B phases reserve liquid made from step 2) is mixed with A phases reserve liquid obtained in step 1), stirs 30min or more, Mixing carries out first time cooling, is cooled to 73 DEG C, then titanium dioxide, iron oxides, iron oxide red, oxidation is added by formula ratio Iron oxide yellow and balance deionized water stir 30min or more, mixing;It carries out second to cool down, is cooled to 48 DEG C, adds step 3) Sodium Hyaluronate made from, Nuciferine, lotus pollen aqueous solution stir 30min or more, mixing;Carry out third time cooling, drop Bi-imidazolidinyl urea, daily essence is added to 38 DEG C, by formula ratio in temperature, stirs 30min or more, mixing, finished product.
Embodiment 4
A kind of skin care compositions containing lotus active constituent, includes the component of following parts by weight:
6 parts of glycerine, 3 parts of 1,3-BDO, 2 parts of saualane, 6 parts of dimethyl silicone polymer, modified dimethyl polysiloxane 5 Part, 8 parts of carbonic acid dioctyl ester, 4 parts of isopropyl myristate, 3 parts of cetostearyl alcohol, 3 parts of cera alba, 3 parts of titanium dioxide, iron oxide 0.1 part of class, 4 parts of sodium chloride, 1 part of Nuciferine, 8 parts of lotus pollen, 1 part of allantoin, 1 part of Sodium Hyaluronate, methyl hydroxybenzoate 0.4 Part, 0.2 part of Nipasol, 0.6 part of bi-imidazolidinyl urea, 0.1 part of iron oxide red, 0.1 part of iron oxide yellow, 0.2 part of daily essence, 40 parts of deionized water.
The modified dimethyl polysiloxane of the present embodiment wins the ABIL EM 90 for creating Degussa-Gao Shi meter Te using Germany.
The preparation method of above-mentioned skin care compositions includes the following steps:
1) weigh appropriate amount of deionized water and preheat, then by formula weigh respectively the sodium chloride, glycerine, 1,3-BDO, Allantoin is put into clean emulsification pot, and mixing is added in the deionized water of preheating, and being sufficiently stirred makes it be uniformly dispersed, heating It is spare as A phases to 82 DEG C;
2) by formula, to weigh the saualane, dimethyl silicone polymer, modified dimethyl polysiloxane, carbonic acid two respectively pungent Ester, isopropyl myristate, cetostearyl alcohol, cera alba, methyl hydroxybenzoate, Nipasol are put into clean oil cauldron, mixing, Being sufficiently stirred makes it be uniformly dispersed, and is heated to 82 DEG C, spare as B phases;
3) Sodium Hyaluronate, Nuciferine, lotus pollen are weighed respectively by formula, then one times or more weight is respectively added Deionized water dissolving, it is spare;
4) B phases reserve liquid made from step 2) is mixed with A phases reserve liquid obtained in step 1), stirs 30min or more, Mixing carries out first time cooling, is cooled to 72 DEG C, then titanium dioxide, iron oxides, iron oxide red, oxidation is added by formula ratio Iron oxide yellow and balance deionized water stir 30min or more, mixing;It carries out second to cool down, is cooled to 47 DEG C, adds step 3) Sodium Hyaluronate made from, Nuciferine, lotus pollen aqueous solution stir 30min or more, mixing;Carry out third time cooling, drop Bi-imidazolidinyl urea, daily essence is added to 37 DEG C, by formula ratio in temperature, stirs 30min or more, mixing, finished product.
Embodiment 5
A kind of skin care compositions containing lotus active constituent, includes the component of following parts by weight:
4 parts of glycerine, 8 parts of 1,3-BDO, 4 parts of saualane, 4 parts of dimethyl silicone polymer, modified dimethyl polysiloxane 4 Part, 5 parts of carbonic acid dioctyl ester, 2 parts of isopropyl myristate, 1 part of cetostearyl alcohol, 2 parts of cera alba, 2 parts of titanium dioxide, iron oxide 0.2 part of class, 3 parts of sodium chloride, 2 parts of Nuciferine, 5 parts of lotus pollen, 2 parts of allantoin, 1.5 parts of Sodium Hyaluronate, methyl hydroxybenzoate 0.5 Part, 0.3 part of Nipasol, 0.4 part of bi-imidazolidinyl urea, 0.2 part of iron oxide red, 0.2 part of iron oxide yellow, 0.4 part of daily essence, 52 parts of deionized water.
The modified dimethyl polysiloxane of the present embodiment wins the ABIL EM 180 for creating Degussa-Gao Shi meter Te using Germany.
The preparation method of above-mentioned skin care compositions includes the following steps:
1) weigh appropriate amount of deionized water and preheat, then by formula weigh respectively the sodium chloride, glycerine, 1,3-BDO, Allantoin is put into clean emulsification pot, and mixing is added in the deionized water of preheating, and being sufficiently stirred makes it be uniformly dispersed, heating It is spare as A phases to 83 DEG C;
2) by formula, to weigh the saualane, dimethyl silicone polymer, modified dimethyl polysiloxane, carbonic acid two respectively pungent Ester, isopropyl myristate, cetostearyl alcohol, cera alba, methyl hydroxybenzoate, Nipasol are put into clean oil cauldron, mixing, Being sufficiently stirred makes it be uniformly dispersed, and is heated to 83 DEG C, spare as B phases;
3) Sodium Hyaluronate, Nuciferine, lotus pollen are weighed respectively by formula, then one times or more weight is respectively added Deionized water dissolving, it is spare;
4) B phases reserve liquid made from step 2) is mixed with A phases reserve liquid obtained in step 1), stirs 30min or more, Mixing carries out first time cooling, is cooled to 71 DEG C, then titanium dioxide, iron oxides, iron oxide red, oxidation is added by formula ratio Iron oxide yellow and balance deionized water stir 30min or more, mixing;It carries out second to cool down, is cooled to 46 DEG C, adds step 3) Sodium Hyaluronate made from, Nuciferine, lotus pollen aqueous solution stir 30min or more, mixing;Carry out third time cooling, drop Bi-imidazolidinyl urea, daily essence is added to 36 DEG C, by formula ratio in temperature, stirs 30min or more, mixing, finished product.
Embodiment 6
A kind of skin care compositions containing lotus active constituent, includes the component of following parts by weight:
2 parts of glycerine, 4 parts of 1,3-BDO, 2 parts of saualane, 6 parts of dimethyl silicone polymer, modified dimethyl polysiloxane 3 Part, 3 parts of carbonic acid dioctyl ester, 1 part of isopropyl myristate, 2 parts of cetostearyl alcohol, 1 part of cera alba, 0.5 part of titanium dioxide, oxidation 0.2 part of iron class, 2 parts of sodium chloride, 0.5 part of Nuciferine, 2 parts of lotus pollen, 0.5 part of allantoin, 0.5 part of Sodium Hyaluronate, oxybenzene 0.3 part of methyl esters, 0.15 part of Nipasol, 0.4 part of bi-imidazolidinyl urea, 0.2 part of iron oxide red, 0.2 part of iron oxide yellow, daily perfume (or spice) Smart 0.2 part, 67 parts of deionized water.
The modified dimethyl polysiloxane of the present embodiment wins the ABIL EM 180 for creating Degussa-Gao Shi meter Te using Germany.
The preparation method of above-mentioned skin care compositions includes the following steps:
1) weigh appropriate amount of deionized water and preheat, then by formula weigh respectively the sodium chloride, glycerine, 1,3-BDO, Allantoin is put into clean emulsification pot, and mixing is added in the deionized water of preheating, and being sufficiently stirred makes it be uniformly dispersed, heating It is spare as A phases to 85 DEG C;
2) by formula, to weigh the saualane, dimethyl silicone polymer, modified dimethyl polysiloxane, carbonic acid two respectively pungent Ester, isopropyl myristate, cetostearyl alcohol, cera alba, methyl hydroxybenzoate, Nipasol are put into clean oil cauldron, mixing, Being sufficiently stirred makes it be uniformly dispersed, and is heated to 85 DEG C, spare as B phases;
3) Sodium Hyaluronate, Nuciferine, lotus pollen are weighed respectively by formula, then one times or more weight is respectively added Deionized water dissolving, it is spare;
4) B phases reserve liquid made from step 2) is mixed with A phases reserve liquid obtained in step 1), stirs 30min or more, Mixing carries out first time cooling, is cooled to 70 DEG C, then titanium dioxide, iron oxides, iron oxide red, oxidation is added by formula ratio Iron oxide yellow and balance deionized water stir 30min or more, mixing;It carries out second to cool down, is cooled to 45 DEG C, adds step 3) Sodium Hyaluronate made from, Nuciferine, lotus pollen aqueous solution stir 30min or more, mixing;Carry out third time cooling, drop Bi-imidazolidinyl urea, daily essence is added to 35 DEG C, by formula ratio in temperature, stirs 30min or more, mixing, finished product.
The preparation of control sample:
The formula of traditional skin care composition is (by weight) as follows:
71 parts of deionized water, 2 parts of glycerine, 4 parts of 1,3-BDO, 2 parts of saualane, 6 parts of dimethyl silicone polymer, stearic acid 3 parts of glyceride, 3 parts of carbonic acid dioctyl ester, 1 part of isopropyl myristate, 2 parts of cetostearyl alcohol, 1 part of cera alba, titanium dioxide 2.0 Part, 0.1 part of iron oxides, 0.5 part of allantoin, 0.2 part of daily essence, 0.3 part of methyl hydroxybenzoate, 0.15 part of Nipasol, double miaows 0.4 part of oxazolidinyl urea, 0.5 part of Sodium Hyaluronate, 0.1 part of iron oxide red, 0.1 part of iron oxide yellow.
Above-mentioned traditional skin care composition is prepared as follows:
1) it weighs appropriate amount of deionized water and preheats, then the glycerine, 1,3-BDO, allantoin are weighed respectively by formula, It puts into clean emulsification pot, mixing is added in the deionized water of preheating, being sufficiently stirred makes it be uniformly dispersed, and is heated to 75-85 DEG C, it is spare as A phases;
2) saualane, dimethyl silicone polymer, tristerin, carbonic acid dioctyl ester, nutmeg are weighed by formula Isopropyl propionate, cetostearyl alcohol, cera alba, methyl hydroxybenzoate, Nipasol are put into clean oil cauldron, and mixing, being sufficiently stirred makes It is uniformly dispersed, and is heated to 75-85 DEG C, spare as B phases;
3) Sodium Hyaluronate is weighed by formula, the deionized water dissolving of one times or more weight is added, it is spare;
4) B phases reserve liquid made from step 2) is mixed with A phases reserve liquid obtained in step 1), stirs 30min or more, Mixing carries out first time cooling, is cooled to 70-75 DEG C, then titanium dioxide, iron oxides, iron oxide red, oxygen is added by formula ratio Change iron oxide yellow and balance deionized water, stirs 30min or more, mixing;It carries out second to cool down, is cooled to 45-50 DEG C, adds Aqueous solution of sodium hyaluronate made from step 3) stirs 30min or more, mixing;Third time cooling is carried out, is cooled to 35-40 DEG C, Bi-imidazolidinyl urea, daily essence is added by formula ratio, stirs 30min or more, mixing, finished product.
Skin moisture-keeping degree, transdermal percentage of water loss, skin elasticity test experiments
One, samples selection
Select 20 people altogether, men and women is fifty-fifty, the age at 24-45 years old, no allergies, no systemic disease and skin disorder, one Non- favour other diseases and unused any skin care item in all.Women is not in the gestational period or nursing period.Voluntary participation full distance test.
Two, material
Skin care item used in this experiment are the present embodiment sample and the control sample by the preparation of above-mentioned formula.
Three, instrument
The Corneometer CM 825 of German Courage+Khazaka Elect ronic GmbH companies production are measured Skin moisture-keeping degree.
The DERMALAB of Cortex Technoiogy ApS companies of Denmark production, has transdermal percentage of water loss and skin elasticity Component b 61 measures transdermal percentage of water loss, skin elasticity.
Four, test condition
It is measured in the interior of 22-24 DEG C of temperature, relative humidity 35-45%, subject enters test cabinet and rests 30 points Start to test after clock.
Five, test method
1, to avoid the difference of left and right arm to the influence of experimental result, by subjects number consecutively, by random digit Table is selected, and determines a tested arm.
2, qualified 20 people of subject, male to female ratio about 1 are selected:1, randomly choose the arm of each subject To test arm.Tested arm is bent into side and is divided into three sections from wrist joint line to elbow joint line, wrist joint nearside bisector midpoint is circle The heart, lcm are that the circle region of radius is testing site, and the corresponding region of a bisector is control point.It is previous in first time standard wash In week and experimental period, tests elbow joint or less and only washed daily with clear water, once in the morning and once at night.Every time when washing, to testing arm The same below equal processing of elbow joint.
3, first time standard wash only carries out standard wash, test area and control zone since at night in experiment arm Same processing, is not washed elsewhere as possible.Using standard laundry method washing, that night begins to use tested material after a week, every time It is used immediately after washing.Test area is uniformly smeared using 0.5g or so skin care item, and extra skin care item are smeared to wrist joint direction, A skin care item are smeared daily, measure corresponding index after skin care item being used continuously l days, 7 days, 30 days and 90 days respectively.
4, using second of test of progress after January.
Standard laundry method:The sponge of diameter 5cm, thick 1cm are saturated with detergent (the 5wt% dodecyl sodium sulfonates of autogamy Sodium water solution), it is gently put on the skin back and forth 50 times in washing zone, often puts 10 times on the skin and soak sponge again once, finally wash most skin table with clear water The detergent in face.
Six, the measurement of test index:
1, transdermal percentage of water loss measurement carries out in air-flow shielded box.To avoid interfering with each other between testing index, measure Sequence is followed successively by skin moisture-keeping degree, transdermal percentage of water loss and skin elasticity, and the time interval of measurement is no less than 5 minutes.
2, skin moisture-keeping degree takes 5 seconds replications of interruption, 10 values of each replication that its average value is taken to be protected for skin Humidity value.It is 1 second that transdermal percentage of water loss, which uses METHOD FOR CONTINUOUS DETERMINATION, read period, surveys 1 minute every time, measures the average value of 60 data For transdermal percentage of water loss.It is 5 seconds that skin elasticity, which measures cycle set, and in 10 periods of METHOD FOR CONTINUOUS DETERMINATION, it is skin bullet to take geometric mean Property value.
3, experimental period is three months, measures three skin moisture-keeping degree, transdermal percentage of water loss, skin elasticity indexs.
Seven, data processing and analysis:
All test sample data make arithmetic mean of instantaneous value, are compareed with blank sample to test specimen and sample itself uses survey Sample cross-reference.
Test result
Remarks:1, the corresponding index measured value in following data table " before experiment " refer to subject skin without appoint Measured value when where is managed.
2, the corresponding index measured value in following data table " before use " refers to that the skin of subject passes through sponge daily It is saturated with detergent to be washed by standard laundry method, washing after a week, uses the corresponding index measured value before skin care item.
3, the corresponding index measured value in following data table " after use " refers to that the skin of subject is saturated with by sponge After a week, then the corresponding index measured value of different time points after skin care item is used continuously in detergent standard wash.
A, skin moisture-keeping degree experimental result is as follows:
Table 1 uses different time skin moisture-keeping degree measured value after skin care item
Note:C1 indicates inventive samples experimental point measured value;
C2 indicates control sample experimental point measured value;
C3 indicates blank control point measured value.
From upper table 1, it is apparent that continuous use inventive samples are after one week, one month, the moisturizing degree of skin is higher than Use control sample and the skin moisture-keeping degree of blank control group;After continuous use three months, the moisturizing degree of skin is apparently higher than Use control sample and the skin moisture-keeping degree of blank control group.
B, transdermal percentage of water loss experimental result is as follows:
Table 2 uses the transdermal percentage of water loss measured value (g/hm of different time after skin care item2)
Note:T1 indicates inventive samples experimental point measured value;
T2 indicates control sample experimental point measured value;
T3 indicates blank control point measured value.
From upper table 2, it is apparent that continuous use inventive samples are after one week, one month, the transdermal percentage of water loss of skin Less than the transdermal percentage of water loss for using control sample and blank control group;After continuous use three months, the transdermal percentage of water loss of skin Significantly lower than the transdermal percentage of water loss for using control sample and blank control group, therefore, inventive samples may make user's Transdermal percentage of water loss is greatly reduced.
C, skin elasticity experimental result is as follows:
Table 3 uses different time skin elasticity measured value (MPa) before and after skin care item
Note:E1 indicates inventive samples experimental point measured value;
E2 indicates control sample experimental point measured value;
E3 indicates blank control point measured value.
From upper table 3, it is apparent that continuous use inventive samples are after one week, one month, skin elasticity measured value is high In the skin elasticity measured value using control sample and blank control group;After continuous use three months, skin elasticity measured value It is apparently higher than the skin elasticity measured value using control sample and blank control group.Inventive samples make the skin of user Elasticity significantly improves.
In conclusion the skin care compositions that the present invention contains lotus active constituent makes full use of the active ingredient of lotus, it is bright The aobvious moisturizing degree for improving skin, reduces the transdermal percentage of water loss of skin, improves skin elasticity.
The above-described embodiments merely illustrate the principles and effects of the present invention, and is not intended to limit the present invention.It is any ripe The personage for knowing this technology can all carry out modifications and changes to above-described embodiment without violating the spirit and scope of the present invention.Cause This, institute is complete without departing from the spirit and technical ideas disclosed in the present invention by those of ordinary skill in the art such as At all equivalent modifications or change, should by the present invention claim be covered.

Claims (10)

1. a kind of skin care compositions containing lotus active constituent, which is characterized in that include the component of following parts by weight:
0-10 parts of glycerine, 0.05-5 parts of saualane, 0.1-10 parts of dimethyl silicone polymer, changes 0-10 parts of 1,3-BDO 0.1-10 parts of dimethyl silicone polymer of property, 0-10 parts of carbonic acid dioctyl ester, 0-5 parts of isopropyl myristate, cetostearyl alcohol 0.1-5 parts, 0.1-5 parts of cera alba, 0.1-5 parts of sodium chloride, 0.05-5 parts of Nuciferine, 0.1-10 parts of lotus pollen, allantois 0.1-5 parts plain, 0.01-2 parts of Sodium Hyaluronate, 0.05-0.5 parts of methyl hydroxybenzoate, 0.05-0.5 parts of Nipasol, double imidazoles 0.1-1 parts of ureine, 0.05-1 parts of essence, 20-90 parts of deionized water.
2. the skin care compositions according to claim 1 containing lotus active constituent, it is characterised in that:Including following weight The component of part:
2-6 parts of glycerine, 3-8 parts of 1,3-BDO, 1-4 parts of saualane, 4-8 parts of dimethyl silicone polymer, modified poly- diformazan 3-8 parts of radical siloxane, 0.1-8 parts of carbonic acid dioctyl ester, 1-4 parts of isopropyl myristate, 1-4 parts of cetostearyl alcohol, white bee 1-4 parts of wax, 1-4 parts of sodium chloride, 0.5-2 parts of Nuciferine, 1-8 parts of lotus pollen, 0.5-2 parts of allantoin, Sodium Hyaluronate 0.1-1.5 parts, 0.3-0.4 parts of methyl hydroxybenzoate, 0.15-0.3 parts of Nipasol, 0.4-0.6 parts of bi-imidazolidinyl urea, essence 0.2-0.5 parts, 30-85 parts of deionized water.
3. the skin care compositions according to claim 1 or 2 containing lotus active constituent, which is characterized in that further include as The component of lower parts by weight:0.1-3 parts of titanium dioxide, 0.05-0.2 parts of iron oxide red, 0.05-0.2 parts of iron oxide yellow.
4. the skin care compositions according to claim 1 or 2 containing lotus active constituent, it is characterised in that:Described poly- two Methylsiloxane is the poly dimethyl of low viscosity dimethyl silicone polymer or low viscosity dimethyl silicone polymer and hyperviscosity The mixture of siloxanes, viscosity≤50mPa s of the low viscosity dimethyl silicone polymer, the poly dimethyl of the hyperviscosity 200,000,00 mPa s of siloxanes viscosity >;The polydimethylsiloxanes of the low viscosity dimethyl silicone polymer and hyperviscosity When alkane mixes, it is 75%-90% that the weight of low viscosity dimethyl silicone polymer, which accounts for the percentage of the two total weight,.
5. the skin care compositions according to claim 1 or 2 containing lotus active constituent, it is characterised in that:The modification Dimethyl silicone polymer is one or both of polyether-modified dimethyl silicone polymer, alkyl-modified dimethyl silicone polymer Mixing.
6. the skin care compositions according to claim 5 containing lotus active constituent, it is characterised in that:It is described polyether-modified The modified polyether group of dimethyl silicone polymer is one or two kinds of mixing in ethylene oxide, propylene oxide.
7. the skin care compositions according to claim 6 containing lotus active constituent, it is characterised in that:It is described alkyl-modified The carbochain of the modified alkyl group of dimethyl silicone polymer is straight chain, and the number of carbon is in the carbochain of the modified alkyl group 10-20。
8. the skin care compositions according to claim 1 or 2 containing lotus active constituent, it is characterised in that:It is described transparent The molecular weight of matter acid sodium is 800,000 to 2,000,000.
9. the preparation method of skin care compositions as claimed in claim 3, which is characterized in that include the following steps:
1)The sodium chloride, glycerine, 1,3-BDO, allantoin are weighed respectively by formula, is mixed, and appropriate amount of deionized water is added, Being sufficiently stirred makes it be uniformly dispersed, heating, spare as A phases;
2)By formula weigh respectively the saualane, dimethyl silicone polymer, modified dimethyl polysiloxane, carbonic acid dioctyl ester, Isopropyl myristate, cetostearyl alcohol, cera alba, methyl hydroxybenzoate, Nipasol, mixing, being sufficiently stirred makes it be uniformly dispersed, Heating, it is spare as B phases;
3)The Sodium Hyaluronate, Nuciferine, lotus pollen are weighed respectively by formula, then are dissolved respectively with appropriate amount of deionized water, It is spare;
4)By step 2)B phases reserve liquid obtained and step 1)In A phases reserve liquid obtained mixing, stir 30min or more, mix It is even, first time cooling is carried out, then titanium dioxide, iron oxide red, iron oxide yellow and balance deionized water is added by formula ratio, stirred Mix 30min or more, mixing;It carries out second to cool down, adds step 3)Sodium Hyaluronate obtained, Nuciferine, lotus pollen Aqueous solution stirs 30min or more, mixing;Third time cooling is carried out, bi-imidazolidinyl urea, essence, stirring is added by formula ratio 30min or more, mixing, finished product.
10. the preparation method of skin care compositions according to claim 9, it is characterised in that:The step 1)With step 2) In be both heated to 75-85 DEG C;Step 3)The dosage of middle deionized water is respectively corresponding Sodium Hyaluronate, Nuciferine, lotus flower One times or more of powder weight;Step 4)Middle first time is cooled to 70-75 DEG C, is cooled to 45-50 DEG C for the second time, is cooled to for the third time 35-40℃。
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