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CN105445084A - Sample dilution device with reusable dilution stations - Google Patents

Sample dilution device with reusable dilution stations Download PDF

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Publication number
CN105445084A
CN105445084A CN201510912454.0A CN201510912454A CN105445084A CN 105445084 A CN105445084 A CN 105445084A CN 201510912454 A CN201510912454 A CN 201510912454A CN 105445084 A CN105445084 A CN 105445084A
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CN
China
Prior art keywords
dilution
cleaning head
chamber
dilution chamber
cleaning
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CN201510912454.0A
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Chinese (zh)
Other versions
CN105445084B (en
Inventor
沙利烽
吴冬
苗新利
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Suzhou Hybiome Biomedical Engineering Co Ltd
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Suzhou Hybiome Biomedical Engineering Co Ltd
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Priority to CN201510912454.0A priority Critical patent/CN105445084B/en
Publication of CN105445084A publication Critical patent/CN105445084A/en
Application granted granted Critical
Publication of CN105445084B publication Critical patent/CN105445084B/en
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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00Sampling; Preparing specimens for investigation
    • G01N1/28Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/38Diluting, dispersing or mixing samples
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00Sampling; Preparing specimens for investigation
    • G01N1/28Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/38Diluting, dispersing or mixing samples
    • G01N2001/386Other diluting or mixing processes

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  • Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Sampling And Sample Adjustment (AREA)

Abstract

The invention discloses a sample dilution device with reusable dilution stations. The sample dilution device comprises a purge chamber, a dilution chamber, a dilution chamber rotation driving part, a cleaning head part and a cleaning head driving part. The purge chamber comprises a purge cavity, the top of which is provided with a liquid feed inlet and the bottom of which is provided with a liquid outlet. The dilution chamber comprises two symmetrically-arranged dilution cavities which have openings facing towards two ends of the dilution chamber. The dilution chamber is rotatably installed inside the purge chamber and can be driven by the dilution chamber rotation driving part to rotate with the two dilution cavities' openings alternately facing upwards. The cleaning head part comprises a liquid inlet tube and a cleaning head. The cleaning head is provided with a liquid outlet hole communicated with the liquid inlet tube. The cleaning head is mounted below the dilution chamber. The cleaning head driving part is connected to the cleaning head part, and the cleaning head can be driven by the cleaning head driving part to move up and down so as to enter or exit from the dilution cavity. According to the invention, dilution stations can be cleaned after dilution. Thus, the same dilution station can be repeatedly used for dilution work.

Description

The reusable Sample Dilution device in a kind of dilution position
Technical field
The invention of this reality relates to technical field of medical instruments, particularly the reusable Sample Dilution device in a kind of dilution position.
Background technology
Chemiluminescence equipment needs when detecting to dilute sample, current most equipment is diluted in certain glass of position of reaction cup by absorption sample and dilution, because the cup position place of reaction cup cannot clean up, so each dilution all needs to take a cup position, this greatly reduces the utilization factor of reaction cup.
Summary of the invention
The technical problem to be solved in the present invention is: by arranging multiple dilution position, in dilution operation is carried out, cleans, make same dilution position can be recycled and reused for dilution work to the dilution position that non-present dilution operation takies, improve dilution process efficiency.
The technical scheme that the present invention takes is specially: the reusable Sample Dilution device in a kind of dilution position, and it comprises: purge chamber, dilution chamber, dilution chamber's rotary drive assembly, cleaning head assembly, and cleaning head driven unit, wherein:
Purge chamber comprises cleaning chambers, and the top of cleaning chambers is provided with filling opening, and bottom is provided with liquid outlet;
Dilution chamber comprises two symmetrically arranged dilution chamber, and two dilution chamber are respectively to the both ends open of dilution chamber; Dilution chamber rotates and is installed in purge chamber, and under the driving of dilution chamber's rotary drive assembly, can rotate in alternate open mode upwards between two dilution chamber;
Cleaning head assembly comprises feed tube and cleaning head, and cleaning head is provided with the fluid hole be connected with feed tube; Cleaning head is installed on below dilution chamber; Cleaning head driven unit connects cleaning head assembly, and cleaning head can move up and down under the driving of cleaning head driven unit, to enter or to exit dilution chamber.
The present invention is when applying, can tune to one of them dilution chamber opening upwards, the dilution chamber of this opening upwards can be used to add sample and dilution dilutes, and enters dilution chamber for the liquid feeding pin that adds sample or dilution by the filling opening at cleaning chambers top.Now can the dilution chamber that Open Side Down be cleaned, namely run by controlling cleaning head driven unit, thus make cleaning head be moved upward in dilution chamber, cleaning fluid and oven dry gas can pass in feed tube, and then spray from the fluid hole cleaning head, dilution chamber cleaned and dries, cleaning the complete cleaning head that can control and move down, exit dilution chamber.Treat that current dilution operation is complete, before diluting next time, run by controlling dilution chamber's rotary drive assembly, thus two dilution chamber positions are exchanged, cleaned dilution chamber now can be utilized to proceed dilution work, and leave the dilution chamber of the rear raffinate of dilution last time, can clean it.
Further, in dilution chamber of the present invention, be provided with splash guard between two dilution chamber, splash guard periphery connects with cleaning chambers inwall.This setting can avoid the cleaning fluid in the matting of below to be splashed into current carrying out, in the dilution chamber of diluting, affects dilution effect and test findings.
In order to make structure more succinct, the present invention also comprises installing plate, purge chamber, dilution chamber's rotary drive assembly, and cleaning head driven unit is installed on installing plate respectively.
In order to make the mobile route of cleaning head more reliable and stable, described installing plate is provided with guide rail, and feed tube can move along guide rail.
Concrete, described dilution chamber rotary drive assembly comprises electric rotating machine, driving wheel, engaged wheel and driving belt, and dilution chamber connects purge chamber sidewall by axis of rotation, and engaged wheel is connected described roller end, driving wheel is connected the output shaft of electric rotating machine, and driving belt connects driving wheel and engaged wheel.
Described cleaning head driven unit comprises linear electric motors and cleaning head erecting frame, and cleaning head assembly is connected by cleaning head erecting frame the output shaft of linear electric motors.
Beneficial effect of the present invention is: by diluting structure and the ingenious combination of wiper mechanism, dilution operation is made to carry out to clean diluting last time the dilution position of applying in process, thus dilution potential energy is enough recycled, greatly improve the efficiency of dilution, and cleaning fluid and gas can be passed into respectively in cleaning head assembly, dilution position is cleaned, and the dilution chamber after cleaned is dried up, to treat dilution next time, cleaning quality is improved.
Accompanying drawing explanation
Figure 1 shows that structural representation of the present invention;
Figure 2 shows that dilution chamber of the present invention rotary drive assembly structural representation;
Figure 3 shows that purge chamber's structural representation;
Figure 4 shows that dilution chamber's structural representation;
Figure 5 shows that cleaning head modular construction schematic diagram;
Figure 6 shows that cleaning head driven unit structural representation.
Embodiment
Further describe below in conjunction with the drawings and specific embodiments.
Composition graphs 1 to Fig. 6, the inventive system comprises purge chamber 1, dilution chamber 2, dilution chamber's rotary drive assembly, cleaning head assembly 4, and cleaning head driven unit, wherein:
As Fig. 3, purge chamber 1 comprises cleaning chambers, and the top of cleaning chambers is provided with filling opening 10, and bottom is provided with liquid outlet 11;
As Fig. 4, dilution chamber 2 comprises the both ends open of two symmetrically arranged dilution chamber 21, two dilution chamber 21 respectively to dilution chamber 2; Dilution chamber 2 rotates and is installed in purge chamber 1, and under the driving of dilution chamber's rotary drive assembly, can rotate in alternate open mode upwards between two dilution chamber 21;
Cleaning head assembly 4 comprises feed tube 42 and cleaning head 41, and cleaning head 41 is provided with the fluid hole 43 be connected with feed tube 42; Cleaning head 41 is installed on below dilution chamber 2; Cleaning head driven unit connects cleaning head assembly 4, and cleaning head 41 can move up and down under the driving of cleaning head driven unit, to enter or to exit dilution chamber 21.
Embodiment
Please refer to Fig. 1, in dilution chamber 2, be provided with splash guard 22 between two dilution chamber 21, splash guard 22 periphery connects with cleaning chambers inwall.This setting can avoid the cleaning fluid in the matting of below to be splashed into current carrying out, in the dilution chamber of diluting, affects dilution effect and test findings.
Composition graphs 1,2 and Fig. 4, in order to make structure more succinct, the present embodiment is also provided with installing plate 3, purge chamber 1, dilution chamber's rotary drive assembly, and cleaning head driven unit is installed on installing plate 3 respectively.
With reference to figure 2, dilution chamber's rotary drive assembly comprises electric rotating machine 51, driving wheel 52, engaged wheel 53 and driving belt 54, dilution chamber 2 connects purge chamber 1 sidewall by axis of rotation, engaged wheel 53 is connected described roller end, driving wheel 52 is connected the output shaft of electric rotating machine 51, and driving belt 54 connects driving wheel 52 and engaged wheel 53.
With reference to figure 6, described cleaning head driven unit comprises linear electric motors 61 and cleaning head erecting frame 62, and cleaning head assembly 4 is connected by cleaning head erecting frame 62 output shaft of linear electric motors 61.
Composition graphs 5 and Fig. 6, in the present embodiment, feed tube 42 is straight tube, and feed tube 42 is fixed on cleaning head erecting frame 62.In order to make the mobile route of cleaning head more reliable and stable, installing plate 3 is provided with guide rail 7, and feed tube 42 can move along guide rail 7.
When applying, dilution chamber is rotated by dilution chamber's rotary drive assembly, make one of them dilution chamber opening upwards, now can add sample in this dilution chamber and dilution dilutes, enter dilution chamber for the liquid feeding pin that adds sample or dilution by the filling opening at cleaning chambers top.The dilution chamber that Open Side Down can be cleaned simultaneously, namely run by controlling cleaning head driven unit, thus make cleaning head be moved upward in dilution chamber, cleaning fluid passes in feed tube, and then spray from the fluid hole cleaning head, dilution chamber is cleaned, cleans the complete cleaning head that can control and move down, exit dilution chamber.Treat that current dilution operation is complete, before diluting next time, run by controlling dilution chamber's rotary drive assembly, thus two dilution chamber positions are exchanged, cleaned dilution chamber now can be utilized to proceed dilution work, and leave the dilution chamber of the rear raffinate of dilution last time, can clean it.The present invention will be by diluting structure and the ingenious combination of wiper mechanism, dilution operation is made to carry out to clean diluting last time the dilution position of applying in process, thus dilution potential energy is enough recycled, greatly improve the efficiency of dilution, and cleaning fluid and gas can be passed into respectively in cleaning head assembly, dilution position is cleaned, and the dilution chamber after cleaned is dried up, to treat dilution next time, cleaning quality is improved.
Described in the present invention, concrete case study on implementation is only better case study on implementation of the present invention, is not used for limiting practical range of the present invention.Namely all equivalences done according to the content of the present patent application the scope of the claims change and modify, all should as technology category of the present invention.

Claims (6)

1. dilute the reusable Sample Dilution device in position, it is characterized in that, comprise purge chamber, dilution chamber, dilution chamber's rotary drive assembly, cleaning head assembly, and cleaning head driven unit, wherein:
Purge chamber comprises cleaning chambers, and the top of cleaning chambers is provided with filling opening, and bottom is provided with liquid outlet;
Dilution chamber comprises two symmetrically arranged dilution chamber, and two dilution chamber are respectively to the both ends open of dilution chamber; Dilution chamber rotates and is installed in purge chamber, and under the driving of dilution chamber's rotary drive assembly, can rotate in alternate open mode upwards between two dilution chamber;
Cleaning head assembly comprises feed tube and cleaning head, and cleaning head is provided with the fluid hole be connected with feed tube; Cleaning head is installed on below dilution chamber; Cleaning head driven unit connects cleaning head assembly, and cleaning head can move up and down under the driving of cleaning head driven unit, to enter or to exit dilution chamber.
2. the reusable Sample Dilution device in dilution position according to claim 1, is characterized in that, in dilution chamber, be provided with splash guard between two dilution chamber, splash guard periphery connects with cleaning chambers inwall.
3. the reusable Sample Dilution device in dilution position according to claim 1, is characterized in that, also comprise installing plate, purge chamber, dilution chamber's rotary drive assembly, and cleaning head driven unit is installed on installing plate respectively.
4. the reusable Sample Dilution device in dilution position according to claim 3, it is characterized in that, described installing plate is provided with guide rail, and feed tube can move along guide rail.
5. the reusable Sample Dilution device in the dilution position according to any one of Claims 1-4, it is characterized in that, dilution chamber's rotary drive assembly comprises electric rotating machine, driving wheel, engaged wheel and driving belt, dilution chamber connects purge chamber's sidewall by axis of rotation, engaged wheel is connected described roller end, driving wheel is connected the output shaft of electric rotating machine, and driving belt connects driving wheel and engaged wheel.
6. the reusable Sample Dilution device in the dilution position according to any one of Claims 1-4, is characterized in that, cleaning head driven unit comprises linear electric motors and cleaning head erecting frame, and cleaning head assembly is connected by cleaning head erecting frame the output shaft of linear electric motors.
CN201510912454.0A 2015-12-11 2015-12-11 One kind dilution reusable Sample Dilution device in position Active CN105445084B (en)

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Application Number Priority Date Filing Date Title
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CN105445084B CN105445084B (en) 2018-01-16

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Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107167360A (en) * 2017-06-16 2017-09-15 苏州长光华医生物医学工程有限公司 A kind of Sample Dilution device
CN108106918A (en) * 2017-12-11 2018-06-01 河南科技大学第附属医院 A kind of medical test liquid feeding diluter
CN108458915A (en) * 2018-03-05 2018-08-28 苏州长光华医生物医学工程有限公司 A kind of dual cavity dilution device
CN110487618A (en) * 2019-09-11 2019-11-22 苏州长光华医生物医学工程有限公司 A kind of band shakes up the Sample Dilution device of function

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20090053824A1 (en) * 2006-01-27 2009-02-26 Randox Laboratories Ltd Assay Device Processing Apparatus and Method
CN102998473A (en) * 2012-12-19 2013-03-27 北京利德曼生化股份有限公司 Full-automatic chemiluminescence immune analyzer
CN202824042U (en) * 2012-09-27 2013-03-27 国家电网公司 Biochemical reaction cup cleaning machine
CN103769022A (en) * 2014-01-16 2014-05-07 东软安德医疗科技有限公司 Automatic biochemical analyzing device and reaction cup set thereof
CN205228922U (en) * 2015-12-11 2016-05-11 苏州长光华医生物医学工程有限公司 Dilute sample diluting device that position can be multiplexing

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20090053824A1 (en) * 2006-01-27 2009-02-26 Randox Laboratories Ltd Assay Device Processing Apparatus and Method
CN202824042U (en) * 2012-09-27 2013-03-27 国家电网公司 Biochemical reaction cup cleaning machine
CN102998473A (en) * 2012-12-19 2013-03-27 北京利德曼生化股份有限公司 Full-automatic chemiluminescence immune analyzer
CN103769022A (en) * 2014-01-16 2014-05-07 东软安德医疗科技有限公司 Automatic biochemical analyzing device and reaction cup set thereof
CN205228922U (en) * 2015-12-11 2016-05-11 苏州长光华医生物医学工程有限公司 Dilute sample diluting device that position can be multiplexing

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107167360A (en) * 2017-06-16 2017-09-15 苏州长光华医生物医学工程有限公司 A kind of Sample Dilution device
CN107167360B (en) * 2017-06-16 2023-08-15 苏州长光华医生物医学工程有限公司 Sample diluting device
CN108106918A (en) * 2017-12-11 2018-06-01 河南科技大学第附属医院 A kind of medical test liquid feeding diluter
CN108106918B (en) * 2017-12-11 2020-07-07 河南科技大学第一附属医院 Liquid adding diluter for medical examination
CN108458915A (en) * 2018-03-05 2018-08-28 苏州长光华医生物医学工程有限公司 A kind of dual cavity dilution device
WO2019169841A1 (en) * 2018-03-05 2019-09-12 苏州长光华医生物医学工程有限公司 Dual-cavity dilution apparatus
CN110487618A (en) * 2019-09-11 2019-11-22 苏州长光华医生物医学工程有限公司 A kind of band shakes up the Sample Dilution device of function

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