CN105125765A - Prescription for treating lung cancer and capable of moistening lung and reducing phlegm and preparation method thereof - Google Patents
Prescription for treating lung cancer and capable of moistening lung and reducing phlegm and preparation method thereof Download PDFInfo
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Abstract
The invention discloses a prescription for treating lung cancer and capable of moistening the lung and reducing phlegm. The prescription comprises, by weight, 8-14 parts of paper mulberry fruit, 10-16 parts of folium isatidis, 9-15 parts of large angiopteris, 7-14 parts of hedyotis caudatifolia, 10-15 parts of fringed pink, 8-16 parts of canscora lucidissima, 7-12 parts of radix trichosanthis, 9-13 parts of Melastoma affine D. Don, 10-14 parts of tussilago farfara, 9-12 parts of hibiscus syriacus, 6-10 parts of Solanum Lyratum Thunb, 7-13 parts of twoflower lycianthes herb, 9-14 parts of clover, 8-15 parts of radix sophorae tonkinensis, 6-14 parts of monochoria vaginalis, 5-10 parts of meadowrue root and rhizome and 11-16 parts of Wuzhishan ginseng. The prescription has the advantages that the prescription is made of Chinese herbal medicine and is safe, free of evident toxic and side effects, and capable of relieving adverse reactions after chemotherapy, the prescription completely conforms to traditional Chinese medicine principles and has effects of nourishing yin and clearing away heat, expelling phlegm to arrest coughing, clearing away lung heat and removing stasis, and the like, the prescription is good in curative effect and stable and reliable in effect, a patient can take the prescription for a long time without economic burden, and the prescription can be easily accepted by the patient.
Description
Technical field
The present invention relates to traditional Chinese medicine field, particularly relate to a kind of moistening the lung and resolving phlegm prescription and preparation method for the treatment of pulmonary carcinoma.
Background technology
Pulmonary carcinoma betides bronchial mucosa epithelium, also known as bronchogenic carcinoma.Long-term smoking a cigarette in a large number is an important paathogenic factor of pulmonary carcinoma.In addition, occupation and environmental exposure, radiation, pulmonary's chronic infection, heredity, atmospheric pollution etc. are all the reasons causing lung cancer morbidity.How asymptomatic pulmonary carcinoma is early stage, and almost the patients with lung cancer of 2/3 has been late period (III phase or IV phase) when medical, and the patient of 95% can have result of clinical detection, and the head of primary tumor, metastatic tumor, General Symptoms or tumor simultaneous phenomenon all patient examines symptom.The typical clinical symptom of pulmonary carcinoma has sputum mixed with blood silk, bronchial tree pressurized, dry cough, heating companion cough, cough up phlegm, chest pain, plantation are sent out with sticky or purulent sputum with bad smell.Lung cancer patient great majority are male, and the ratio of boys and girls is about 4 ~ 8:1, and patient age is mostly more than 40 years old.The treatment of pulmonary carcinoma has surgical intervention, radiotherapy, chemotherapy and immunotherapy.Current surgical intervention has been acknowledged as the prefered method for the treatment of pulmonary carcinoma.
Publication No. CN103800719A(application number 201410041332.4) Chinese patent literature disclose a kind of Chinese medicine for the treatment of pulmonary carcinoma, Fructus Ligustri Lucidi 4-9 gram, Herba Lophatheri 1-5 gram, Rhizoma Paridis 5-15 gram, Flos Carthami 10-20 gram, Radix Achyranthis Bidentatae 6-10 gram, Rhizoma Corydalis 4-15 gram, Radix Astragali 5-10 gram, Radix Notoginseng 3-8 gram.Publication No. CN103623349A(application number 201310639157.4) Chinese patent literature disclose a kind of lung cancer drug, be made up of by certain weight ratio 41 taste medicines such as crude drug Pseudobulbus Cremastrae Seu Pleiones, Semen Strychni, Nidus Vespae, Mylabris, Herba Solani Nigri, Herba Scutellariae Barbatae Rhizoma Sparganii, Sargassum, Thallus Laminariae (Thallus Eckloniae), Radix Codonopsis, the Radix Astragali, Radix Rehmanniae Preparata, the Radix Polygoni Multiflori, the Rhizoma Atractylodis Macrocephalae, six songs, Fructus Crataegi, Fructus Aurantii, Rhizoma Cyperi, Rhizoma Curcumae Longae, Eupolyphaga Seu Steleophagas.Publication No. CN104800538A(application number 201510251333.6) Chinese patent literature disclose a kind of Chinese medicine for the treatment of pulmonary carcinoma, Rhizoma Paridis 10 ~ 20 parts, Bulbus Fritillariae Cirrhosae 5 ~ 10 parts, Rabdosia rubescens 5 ~ 15 parts, dried Alumen 10 ~ 20 parts, the Radix Astragali 10 ~ 20 parts, Borneolum Syntheticum 10 ~ 20 parts, Flos Lonicerae 5 ~ 15 parts, Radix Ginseng 5 ~ 10 parts, Ganoderma 5 ~ 10 parts, SHANZHIZI 5 ~ 15 parts, Poria 15 ~ 30 parts, Rhizoma Acori Calami 10 ~ 20 parts, Herba Andrographis 5 ~ 10 parts, 10 ~ 20 parts, Radix Glycyrrhizae, Rhizoma Polygoni Cuspidati 25 ~ 40 parts, lobule buys numb Teng 15 ~ 25 parts, Radix Tripterygii Wilfordii 5 ~ 10 parts, Herba Scutellariae Barbatae 5 ~ 15 parts, Hedyotidis Diffusae 5 ~ 10 parts.
Surgical intervention pulmonary carcinoma needs to possess certain condition and just can perform the operation, and is not suitable for all patients, and medical expense is high, have a big risk, patients ' life quality is poor, and Chinese medicine risk is low, expense is few, therefore needs to develop the traditional Chinese medical science formula that a kind of determined curative effect treats pulmonary carcinoma reliably.
Summary of the invention
For the deficiencies in the prior art, the object of this invention is to provide a kind of moistening the lung and resolving phlegm prescription and the preparation method of preparing treatment pulmonary carcinoma that is simple, that easily take for a long time.
Technical scheme of the present invention is:
The moistening the lung and resolving phlegm prescription for the treatment of pulmonary carcinoma, is prepared from primarily of following bulk drugs, is mass parts: Fructus Broussonetiae 8-14, Folium Isatidis 10-16, Angiopteris magna Ching (Angiopteris majuscula Ching) 9-15, Herba Hedyotis Lanceae 7-14, Herba Dianthi 10-15, Herba Canscorae 8-16, Radix Trichosanthis 7-12, broken bowl palm foot tree 9-13, Flos Farfarae 10-14, Fructus Hibisci 9-12, Herba Solani Lyrati 6-10, Herba Lycianthis Biflorae 7-13, Herba Galii Bungei 9-14, Radix Sophorae Tonkinensis 8-15, Herba monochoriae vaginalis 6-14, Radix et Rhizoma Thalictri 5-10, Radix Abelmoschi Sagittifolii 11-16.
In preferred scheme, Fructus Broussonetiae 10-12, Folium Isatidis 12-14, Angiopteris magna Ching (Angiopteris majuscula Ching) 10-14, Herba Hedyotis Lanceae 9-12, Herba Dianthi 11-14, Herba Canscorae 10-14, Radix Trichosanthis 9-10, broken bowl palm foot tree 10-12, Flos Farfarae 11-13, Fructus Hibisci 10-11, Herba Solani Lyrati 7-9, Herba Lycianthis Biflorae 9-11, Herba Galii Bungei 10-13, Radix Sophorae Tonkinensis 10-13, Herba monochoriae vaginalis 8-12, Radix et Rhizoma Thalictri 6-9, Radix Abelmoschi Sagittifolii 13-14.
Be more preferably, Fructus Broussonetiae 11, Folium Isatidis 13, Angiopteris magna Ching (Angiopteris majuscula Ching) 12, Herba Hedyotis Lanceae 10.5, Herba Dianthi 12.5, Herba Canscorae 12, Radix Trichosanthis 9.5, broken bowl palm foot tree 11, Flos Farfarae 12, Fructus Hibisci 10.5, Herba Solani Lyrati 8, Herba Lycianthis Biflorae 10, Herba Galii Bungei 11.5, Radix Sophorae Tonkinensis 11.5, Herba monochoriae vaginalis 10, Radix et Rhizoma Thalictri 7.5, Radix Abelmoschi Sagittifolii 13.5.
The moistening the lung and resolving phlegm prescription of described treatment pulmonary carcinoma, be made into pharmaceutically acceptable decoction, its preparation method is:
(1) get Fructus Broussonetiae and Fructus Hibisci roguing to clean, be placed in slow fire in frying pan and fry to buff, take out, mix thoroughly with Sucus Zingberis and saline, moistening 15-20 minute (preferred, moistening 16-19 minute; Be more preferably, moistening 17 minutes), take out, dry;
(2) get Radix Trichosanthis and Herba Lycianthis Biflorae to clean, with bean curd with boiling, well-done rear taking-up, section, dries;
(3) Radix Sophorae Tonkinensis, Radix et Rhizoma Thalictri and Radix Abelmoschi Sagittifolii are cleaned, section, infiltrates 20 minutes with yellow wine, takes out, is placed in frying pan, together fries with Oryza glutinosa, and when frying Huang micro-to crude drug surface, take out, sieve removes Oryza glutinosa, dries;
(4) Angiopteris magna Ching (Angiopteris majuscula Ching), Herba Hedyotis Lanceae, Herba Dianthi, broken bowl palm foot tree, Herba Solani Lyrati and Herba monochoriae vaginalis roguing are cleaned, together add decocting in water with step (2) (3) made crude drug, big fire is boiled rear little fire and is decocted 25-35 minute (preferred, 27-33 minute decocted by little fire; Be more preferably, little fire decocts 30 minutes), Guan Huo, adds Folium Isatidis, Herba Canscorae, Flos Farfarae and Herba Galii Bungei vexed 20 minutes, filters, and collects filtrate;
(5) medicated powder is made in made for step (1) crude drug pulverizing, join in step (4) made filtrate, mix thoroughly, obtain decoction.
The preparation method of the moistening the lung and resolving phlegm prescription decoction of described treatment pulmonary carcinoma, the 7-9 that step (4) amount of water is boiled crude drug quality is (preferred, amount of water is 8 times of boiled crude drug quality) doubly.
The moistening the lung and resolving phlegm prescription of described treatment pulmonary carcinoma, be made into pharmaceutically acceptable powder, its preparation method is:
(1) get Fructus Broussonetiae and Fructus Hibisci roguing to clean, be placed in slow fire in frying pan and fry to buff, take out, mix thoroughly with Sucus Zingberis and saline, moistening 15-20 minute (preferred, moistening 16-19 minute; Be more preferably, moistening 17 minutes), take out, dry;
(2) get Radix Trichosanthis and Herba Lycianthis Biflorae to clean, with bean curd with boiling, well-done rear taking-up, section, dries;
(3) Radix Sophorae Tonkinensis, Radix et Rhizoma Thalictri and Radix Abelmoschi Sagittifolii are cleaned, section, infiltrates 20 minutes with yellow wine, takes out, is placed in frying pan, together fries with Oryza glutinosa, and when frying Huang micro-to crude drug surface, take out, sieve removes Oryza glutinosa, dries;
(4) Folium Isatidis, Angiopteris magna Ching (Angiopteris majuscula Ching), Herba Hedyotis Lanceae, Herba Dianthi, Herba Canscorae, broken bowl palm foot tree, Flos Farfarae, Herba Solani Lyrati, Herba Galii Bungei and Herba monochoriae vaginalis roguing are cleaned, pulverize and sieve together with step (1) (2) (3) made crude drug, obtain powder.
The preparation method of the moistening the lung and resolving phlegm prescription powder of described treatment pulmonary carcinoma, step (4) was pulverized 200-280 mesh sieve and (preferably, was pulverized 220-260 mesh sieve; Be more preferably, pulverized 240 mesh sieves).
The moistening the lung and resolving phlegm prescription of described treatment pulmonary carcinoma, be made into pharmaceutically acceptable pill, its preparation method is:
(1) get Fructus Broussonetiae and Fructus Hibisci roguing to clean, be placed in slow fire in frying pan and fry to buff, take out, mix thoroughly with Sucus Zingberis and saline, moistening 15-20 minute (preferred, moistening 16-19 minute; Be more preferably, moistening 17 minutes), take out, dry;
(2) get Radix Trichosanthis and Herba Lycianthis Biflorae to clean, with bean curd with boiling, well-done rear taking-up, section, dries;
(3) Radix Sophorae Tonkinensis, Radix et Rhizoma Thalictri and Radix Abelmoschi Sagittifolii are cleaned, section, infiltrates 20 minutes with yellow wine, takes out, is placed in frying pan, together fries with Oryza glutinosa, and when frying Huang micro-to crude drug surface, take out, sieve removes Oryza glutinosa, dries;
(4) Folium Isatidis, Angiopteris magna Ching (Angiopteris majuscula Ching), Herba Hedyotis Lanceae, Herba Dianthi, Herba Canscorae, broken bowl palm foot tree, Flos Farfarae, Herba Solani Lyrati, Herba Galii Bungei and Herba monochoriae vaginalis roguing are cleaned, pulverize and sieve together with step (1) (2) (3) made crude drug, make medicated powder, add yellow wine and refined honey water, generally make ball, obtain pill.
The preparation method of the moistening the lung and resolving phlegm prescription pill of described treatment pulmonary carcinoma, step (4) was pulverized 100-160 mesh sieve and (preferably, was pulverized 120-140 mesh sieve; Be more preferably, pulverized 130 mesh sieves).
The moistening the lung and resolving phlegm prescription of described treatment pulmonary carcinoma, be made into pharmaceutically acceptable capsule, its preparation method is:
(1) get Fructus Broussonetiae and Fructus Hibisci roguing to clean, be placed in slow fire in frying pan and fry to buff, take out, mix thoroughly with Sucus Zingberis and saline, moistening 15-20 minute (preferred, moistening 16-19 minute; Be more preferably, moistening 17 minutes), take out, dry;
(2) get Radix Trichosanthis and Herba Lycianthis Biflorae to clean, with bean curd with boiling, well-done rear taking-up, section, dries;
(3) Radix Sophorae Tonkinensis, Radix et Rhizoma Thalictri and Radix Abelmoschi Sagittifolii are cleaned, section, infiltrates 20 minutes with yellow wine, takes out, is placed in frying pan, together fries with Oryza glutinosa, and when frying Huang micro-to crude drug surface, take out, sieve removes Oryza glutinosa, dries;
(4) Angiopteris magna Ching (Angiopteris majuscula Ching), Herba Hedyotis Lanceae, Herba Dianthi, broken bowl palm foot tree, Herba Solani Lyrati and Herba monochoriae vaginalis roguing are cleaned, decocting in water (amount of water is 8 times of boiled crude drug quality) is together added with step (2) (3) made crude drug, big fire is boiled rear little fire and is decocted 25-35 minute, add Folium Isatidis, Herba Canscorae, Flos Farfarae and Herba Galii Bungei vexed 20 minutes, filter, collect filtrate, filtering residue adds water and again decocts, merge twice filtrate, add and be condensed into thick paste;
(5) medicated powder is made in made for step (1) crude drug pulverizing, join in step (4) made thick paste, mix thoroughly, with sucrose and 10% starch slurry soft material, granulate, dry, granulate, obtained granule, incapsulates, obtains capsule.
The preparation method of the moistening the lung and resolving phlegm prescription capsule of described treatment pulmonary carcinoma, step (4) big fire is boiled rear little fire and is decocted little fire and decoct 27-33 minute (preferred, little fire decocts 30 minutes).
The moistening the lung and resolving phlegm prescription science collocation for the treatment of pulmonary carcinoma provided by the invention, dialectical treatmert, preparation is simple.In addition, excellent results of the present invention also shows:
1, the present invention is made up of Chinese medicinal plant material, safely without obvious toxic-side effects, and the untoward reaction symptom occurred after simultaneously also can alleviating chemotherapy;
2, this prescription meets Chinese medicine principle completely, can play the effects such as nourishing YIN and clearing away heat, expelling phlegm for arresting cough, lung heat clearing eliminating stagnation;
3, good effect of the present invention, effect stability is reliable, and long-term taking is without financial burden, and patient easily accepts.
Detailed description of the invention
Describe technical scheme of the present invention in detail below in conjunction with embodiment and experimental example, but protection domain is not limited thereto.
The pharmacology of the present invention's main raw material of Chinese medicine used is as follows:
Fructus Broussonetiae: base is former: be the fruit of moraceae plants Broussonetia papyrifera.Nature and flavor: sweet, cold.Gui Jing: enter liver, spleen, kidney channel.Function cures mainly: nourishing kidney, liver heat removing, improving eyesight.Control asthenia, blurred vision, corneal nebula, aqueous vapor edema.
Folium Isatidis: base is former: be leaf or the branch and leaf of Verbenaceae Herba Diclipterae Chinensis, few section plant polygonum tinctorium ait., cruciferae isatis, careless Folium Isatidis or acanthaceous vegetable acanthaceous indigo etc.Nature and flavor: bitter, cold.Gui Jing: GUIXIN, stomach warp.Function cures mainly: heat-clearing and toxic substances removing, blood cooling and ecchymoses removing.Join the army for pathogenic warmth, unconsciousness due to high fever, sends out speckle dermexanthesis, jaundice, hematodiarrhoea, mumps, sore throat, erysipelas, carbuncle.
Angiopteris magna Ching (Angiopteris majuscula Ching): base is former: be the root stock of the large lotus throne Herba pteridii latiusculi of Angiopteridaceae plant.Nature and flavor: pained, cold.Function cures mainly: heat-clearing and toxic substances removing, hemostasis, damp eliminating diuresis.Control enteritis, dysentery, dyspepsia abdominal distention.Oedema due to nephritis, pulmonary tuberculosis, hemoptysis, metrorrhagia, traumatic injury, rheumatism, gastric and duodenal ulcers.
Herba Hedyotis Lanceae: base is former: be the herb of dicotyledon medicine Maguireothamnus speciosus Herba Hedyotis Lanceae.Nature and flavor: sweet are flat.Gui Jing: lung, liver, spleen channel.Function cures mainly: relieving cough and resolving phlegm, spleen invigorating removing food stagnancy.Main bronchus asthma, bronchitis, pulmonary tuberculosis is spat blood, infantile malnutrition, traumatic injury, traumatic hemorrhage.
Herba Dianthi: base is former: be the wounded in the battle herb of pinkwort Herba Dianthi or Dianthus chinensis.Nature and flavor: bitter, cold.Gui Jing: GUIXIN, small intestine meridian.Function cures mainly: inducing diuresis for treating stranguria syndrome, and removing blood stasis stimulates the menstrual flow.For pyretic stranguria, stranguria with blood, stranguria caused by urinary stone, urinary obstruction, drenches the puckery pain of drop, menstruation apolipsis.
Herba Canscorae: base is former: be the herb of gentianaceae plant Herba Canscorae.Nature and flavor: micro-sweet, micro-hardship are flat.Function cures mainly: heat-clearing and toxic substances removing, cough-relieving, pain relieving.For cough due to lung-heat, stomachache, icterohepatitis, venom.
Radix Trichosanthis: base is former: be the root of cucurbitaceous plant Fructus Trichosanthis.Nature and flavor: sweet, micro-hardship, is slightly cold.Gui Jing: attach to the lung and stomach meridians.Function cures mainly: clearing away heat and promoting production of body fluid, detumescence and apocenosis.For calentura excessive thirst, lung-heat type cough, interior-heat is quenched one's thirst, sore swollen toxin.
Broken bowl palm foot tree: base is former: be the Herb of Melastomateae plants Herba Melastomatis polyanthi.Nature and flavor: bitter in the mouth, puckery, cool in nature.Function cures mainly: clearing away heat-damp and promoting diuresis, removing stasis to stop bleeding, removing toxic substances.Main enteritis, dysentery, hepatitis, malaria, migraine, spitting of blood, hemoptysis, epistaxis, has blood in stool, hematuria, menoxenia, difficult labour, cervical erosion, cyclomastopathy, carbuncle furuncle and phyma poison, burn due to hot liquid or fire, eczema, and traumatic injury wound is swollen.
Flos Farfarae: base is former: be the alabastrum of feverfew coltsfoot.Nature and flavor: pungent, micro-hardship, temperature.Gui Jing: return lung meridian.Function cures mainly: nourishing the lung to keep the adverse QI downward, relieving cough and resolving phlegm.Cough for new chronic cough, dyspnea and cough with excessive sputum, chronic cough hemoptysis.
Fructus Hibisci: base is former: be the fruit of Malvaceae plant Hibiscus syriacus L..Nature and flavor: sweet, cold.Gui Jing: lung, the heart, Liver Channel.Function cures mainly: removing heat from the lung and dissipating phlegm, only headache, removing toxic substances.Main phlegm dyspnea cough, bronchitis, migraine and general headache, impetigo, eczema.
Herba Solani Lyrati: base is former: be the herb of plant of Solanaceae Herba Solani Lyrati.Nature and flavor: sweetness and bitterness, cold.Function cures mainly: heat clearing away, and dampness removing dispels the wind, removing toxic substances.Treating malaria disease, jaundice, edema, gonorrhea, rheumatic arthritis, erysipelas, furuncle.
Herba Lycianthis Biflorae: base is former: be the Herb of plant of Solanaceae ten calyx eggplant.Nature and flavor: bitter in the mouth, cool in nature.Function cures mainly: heat-clearing and toxic substances removing, expelling phlegm for arresting cough.Cure mainly cough, asthma, dysentery, pyretic stranguria, lyssodexis, furuncle is red and swollen, traumatic hemorrhage.
Herba Galii Bungei: base is former: be the herb of Maguireothamnus speciosus four leaf humulus or thin four leaf humulus.Nature and flavor: sweet are flat.Function cures mainly: heat clearing away, diuresis, removing toxic substances, detumescence.Control urinary tract infection, leucorrhea with red and white discharge, dysentery, carbuncle, traumatic injury.
Radix Sophorae Tonkinensis: base is former: the root being mainly leguminous plant root of subprostrate sophora.Nature and flavor: bitter, cold, poisonous.Gui Jing: attach to the lung and stomach meridians.Function cures mainly: heat-clearing and toxic substances removing, detumescence sore-throat relieving.Pent up for fire-toxin, laryngopharynx swelling and pain, gingivitis.
Herba monochoriae vaginalis: base is former: be the Herb of Pontederiaceae plant Herba monochoriae vaginalis.Nature and flavor: sweet are cool.Function cures mainly: heat-clearing and toxic substances removing.For enteritis, dysentery, laryngopharynx swelling and pain, gingival abscess, worm venom is controlled in external, furuncle.
Radix et Rhizoma Thalictri: base is former: be rhizome and the root of the leafy Thalictrum aquilegifolium L. var. sibiricum Regel of ranunculaceae plant, baikal meadowrue root etc.Nature and flavor: bitter, cold.Gui Jing: enter the heart, liver, gallbladder, large intestine four warp.Function cures mainly: heat clearing and damp drying, eliminating fire and detoxication.For enteritis, dysentery, jaundice, conjunctival congestion and swelling pain.
Radix Abelmoschi Sagittifolii: base is former: be the root of Malvaceae plant arrowleaf abelmoschus.Nature and flavor: micro-sweet are flat.Function cures mainly: nourishing YIN and clearing away heat, and evacuation of pus is drawn out pus by applying a plaster to the affected part.Cure mainly pulmonary tuberculosis, xeropulmonary cough, puerperal constipation, neurasthenia.Carbuncle pyogenic infections from tumour or sore is controlled in external.
embodiment 1the moistening the lung and resolving phlegm prescription for the treatment of pulmonary carcinoma, is prepared from (every part of 10g) primarily of following bulk drugs: Fructus Broussonetiae 8 parts, Folium Isatidis 10 parts, Angiopteris magna Ching (Angiopteris majuscula Ching) 9 parts, Herba Hedyotis Lanceae 7 parts, Herba Dianthi 10 parts, Herba Canscorae 8 parts, Radix Trichosanthis 7 parts, broken bowl palm foot sets 9 parts, Flos Farfarae 10 parts, Fructus Hibisci 9 parts, Herba Solani Lyrati 6 parts, Herba Lycianthis Biflorae 7 parts, Herba Galii Bungei 9 parts, Radix Sophorae Tonkinensis 8 parts, Herba monochoriae vaginalis 6 parts, Radix et Rhizoma Thalictri 5 parts, Radix Abelmoschi Sagittifolii 11 parts.
The preparation method of the moistening the lung and resolving phlegm prescription decoction of above-mentioned treatment pulmonary carcinoma is:
(1) get Fructus Broussonetiae and Fructus Hibisci roguing to clean, be placed in slow fire in frying pan and fry to buff, take out, mix thoroughly with Sucus Zingberis and saline, moistening 17 minutes, take out, dry;
(2) get Radix Trichosanthis and Herba Lycianthis Biflorae to clean, with bean curd with boiling, well-done rear taking-up, section, dries;
(3) Radix Sophorae Tonkinensis, Radix et Rhizoma Thalictri and Radix Abelmoschi Sagittifolii are cleaned, section, infiltrates 20 minutes with yellow wine, takes out, is placed in frying pan, together fries with Oryza glutinosa, and when frying Huang micro-to crude drug surface, take out, sieve removes Oryza glutinosa, dries;
(4) Angiopteris magna Ching (Angiopteris majuscula Ching), Herba Hedyotis Lanceae, Herba Dianthi, broken bowl palm foot tree, Herba Solani Lyrati and Herba monochoriae vaginalis roguing are cleaned, decocting in water (amount of water is 8 times of boiled crude drug quality) is together added with step (2) (3) made crude drug, big fire is boiled rear little fire and is decocted 30 minutes, Guan Huo, add Folium Isatidis, Herba Canscorae, Flos Farfarae and Herba Galii Bungei vexed 20 minutes, filter, collect filtrate;
(5) medicated powder is made in made for step (1) crude drug pulverizing, join in step (4) made filtrate, mix thoroughly, obtain decoction.
embodiment 2the moistening the lung and resolving phlegm prescription for the treatment of pulmonary carcinoma, is prepared from (every part of 10g) primarily of following bulk drugs: Fructus Broussonetiae 14 parts, Folium Isatidis 16 parts, Angiopteris magna Ching (Angiopteris majuscula Ching) 15 parts, Herba Hedyotis Lanceae 14 parts, Herba Dianthi 15 parts, Herba Canscorae 16 parts, Radix Trichosanthis 12 parts, broken bowl palm foot sets 13 parts, Flos Farfarae 14 parts, Fructus Hibisci 12 parts, Herba Solani Lyrati 10 parts, Herba Lycianthis Biflorae 13 parts, Herba Galii Bungei 14 parts, Radix Sophorae Tonkinensis 15 parts, Herba monochoriae vaginalis 14 parts, Radix et Rhizoma Thalictri 10 parts, Radix Abelmoschi Sagittifolii 16 parts.
The preparation method of the moistening the lung and resolving phlegm prescription powder for the treatment of pulmonary carcinoma is:
(1) get Fructus Broussonetiae and Fructus Hibisci roguing to clean, be placed in slow fire in frying pan and fry to buff, take out, mix thoroughly with Sucus Zingberis and saline, moistening 17 minutes, take out, dry;
(2) get Radix Trichosanthis and Herba Lycianthis Biflorae to clean, with bean curd with boiling, well-done rear taking-up, section, dries;
(3) Radix Sophorae Tonkinensis, Radix et Rhizoma Thalictri and Radix Abelmoschi Sagittifolii are cleaned, section, infiltrates 20 minutes with yellow wine, takes out, is placed in frying pan, together fries with Oryza glutinosa, and when frying Huang micro-to crude drug surface, take out, sieve removes Oryza glutinosa, dries;
(4) Folium Isatidis, Angiopteris magna Ching (Angiopteris majuscula Ching), Herba Hedyotis Lanceae, Herba Dianthi, Herba Canscorae, broken bowl palm foot tree, Flos Farfarae, Herba Solani Lyrati, Herba Galii Bungei and Herba monochoriae vaginalis roguing are cleaned, pulverized 240 mesh sieves together with step (1) (2) (3) made crude drug, obtain powder.
Model case: xxx, female, 63 years old.Cough uncomfortable in chest 3 years, increases the weight of two weeks, examination in hospital, be diagnosed as upper right pulmonary carcinoma, carry out lobectomy of lungs operation, postoperative pathological biopsy display right upper lung Bronchiolo-alveolar cell carcinoma, is transferred to hilar lymph node, feeling of oppression and pain in the chest, asthma, cough with copious phlegm, with right pleural effusion, postoperatively carry out chemotherapy, because untoward reaction serious symptom is uncomfortable, stop chemotherapy, select tcm therapy.
Take the moistening the lung and resolving phlegm prescription powder of the present embodiment gained treatment pulmonary carcinoma, every day 2 times, each 3-5g, warm boiled water, 20 days courses for the treatment of.After taking a course for the treatment of, patient's pain uncomfortable in chest, asthma alleviate, and expectoration reduces, sleep improvement, after taking two courses for the treatment of, hydrothorax reduces, and malaise symptoms obviously alleviates, after taking four courses for the treatment of, patient clinical symptom disappears substantially, hydrothorax absorbs completely, foci disappearance, follows up a case by regular visits to patient without recurrence after 2 years.
embodiment 3the moistening the lung and resolving phlegm prescription for the treatment of pulmonary carcinoma, is prepared from (every part of 10g) primarily of following bulk drugs: Fructus Broussonetiae 10 parts, Folium Isatidis 12 parts, Angiopteris magna Ching (Angiopteris majuscula Ching) 10 parts, Herba Hedyotis Lanceae 9 parts, Herba Dianthi 11 parts, Herba Canscorae 10 parts, Radix Trichosanthis 9 parts, broken bowl palm foot sets 10 parts, Flos Farfarae 11 parts, Fructus Hibisci 10 parts, Herba Solani Lyrati 7 parts, Herba Lycianthis Biflorae 9 parts, Herba Galii Bungei 10 parts, Radix Sophorae Tonkinensis 10 parts, Herba monochoriae vaginalis 8 parts, Radix et Rhizoma Thalictri 6 parts, Radix Abelmoschi Sagittifolii 13 parts.
The preparation method of the moistening the lung and resolving phlegm prescription pill for the treatment of pulmonary carcinoma is:
(1) get Fructus Broussonetiae and Fructus Hibisci roguing to clean, be placed in slow fire in frying pan and fry to buff, take out, mix thoroughly with Sucus Zingberis and saline, moistening 17 minutes, take out, dry;
(2) get Radix Trichosanthis and Herba Lycianthis Biflorae to clean, with bean curd with boiling, well-done rear taking-up, section, dries;
(3) Radix Sophorae Tonkinensis, Radix et Rhizoma Thalictri and Radix Abelmoschi Sagittifolii are cleaned, section, infiltrates 20 minutes with yellow wine, takes out, is placed in frying pan, together fries with Oryza glutinosa, and when frying Huang micro-to crude drug surface, take out, sieve removes Oryza glutinosa, dries;
(4) Folium Isatidis, Angiopteris magna Ching (Angiopteris majuscula Ching), Herba Hedyotis Lanceae, Herba Dianthi, Herba Canscorae, broken bowl palm foot tree, Flos Farfarae, Herba Solani Lyrati, Herba Galii Bungei and Herba monochoriae vaginalis roguing are cleaned, 130 mesh sieves were pulverized together with step (1) (2) (3) made crude drug, make medicated powder, add yellow wine and refined honey water, generally make ball, obtain pill.
Model case: xxx, man, 56 years old.Main suit: chest pain is uncomfortable in chest, expectoration is mingled with the blood streak 1 wheat harvesting period, examination in hospital, and figure is become thin, chest pain, feel oppressed, cough, uttering phlegm is with the blood streak, soreness of the waist and knees, body is tired weak, sleeps poor, dark tongue quality, tongue is white, and deep pulse is thin and delicate, two lung audible and moist rales, auxiliary examination, CT points out superior lobe of left lung central type carcinoma of lung (mid-term), there is hydrops in thoracic cavity, and pathology biopsy is shown as scale cancer, is diagnosed as pulmonary carcinoma.
Coordinate normal chemotherapy protocols, and take the moistening the lung and resolving phlegm prescription pill of the present embodiment gained treatment pulmonary carcinoma, adopt every day 2 times, each 4, with warm water delivery service, 20 days courses for the treatment of.After taking a course for the treatment of, cough, uncomfortable in chestly obviously to alleviate, appetite increases, spirit takes a turn for the better, and after taking three courses for the treatment of, malaise symptoms disappears completely, lump obviously reduces, and hydrothorax absorbs completely, after taking four courses for the treatment of, lump is without significant change, also without other metastasis, health without other malaise symptoms, patient's drug withdrawal, follow up a case by regular visits to after 2 years, patient body is in good condition.
embodiment 4the moistening the lung and resolving phlegm prescription for the treatment of pulmonary carcinoma, is prepared from (every part of 10g) primarily of following bulk drugs: Fructus Broussonetiae 12 parts, Folium Isatidis 14 parts, Angiopteris magna Ching (Angiopteris majuscula Ching) 14 parts, Herba Hedyotis Lanceae 12 parts, Herba Dianthi 14 parts, Herba Canscorae 14 parts, Radix Trichosanthis 10 parts, broken bowl palm foot sets 12 parts, Flos Farfarae 13 parts, Fructus Hibisci 11 parts, Herba Solani Lyrati 9 parts, Herba Lycianthis Biflorae 11 parts, Herba Galii Bungei 13 parts, Radix Sophorae Tonkinensis 13 parts, Herba monochoriae vaginalis 12 parts, Radix et Rhizoma Thalictri 9 parts, Radix Abelmoschi Sagittifolii 14 parts.
The preparation method of the moistening the lung and resolving phlegm prescription capsule for the treatment of pulmonary carcinoma is:
(1) get Fructus Broussonetiae and Fructus Hibisci roguing to clean, be placed in slow fire in frying pan and fry to buff, take out, mix thoroughly with Sucus Zingberis and saline, moistening 17 minutes, take out, dry;
(2) get Radix Trichosanthis and Herba Lycianthis Biflorae to clean, with bean curd with boiling, well-done rear taking-up, section, dries;
(3) Radix Sophorae Tonkinensis, Radix et Rhizoma Thalictri and Radix Abelmoschi Sagittifolii are cleaned, section, infiltrates 20 minutes with yellow wine, takes out, is placed in frying pan, together fries with Oryza glutinosa, and when frying Huang micro-to crude drug surface, take out, sieve removes Oryza glutinosa, dries;
(4) Angiopteris magna Ching (Angiopteris majuscula Ching), Herba Hedyotis Lanceae, Herba Dianthi, broken bowl palm foot tree, Herba Solani Lyrati and Herba monochoriae vaginalis roguing are cleaned, decocting in water (amount of water is 8 times of boiled crude drug quality) is together added with step (2) (3) made crude drug, big fire is boiled rear little fire and is decocted 30 minutes, add Folium Isatidis, Herba Canscorae, Flos Farfarae and Herba Galii Bungei vexed 20 minutes, filter, collect filtrate, filtering residue adds water and again decocts, merge twice filtrate, add and be condensed into thick paste;
(5) medicated powder is made in made for step (1) crude drug pulverizing, join in step (4) made thick paste, mix thoroughly, with sucrose and 10% starch slurry soft material, granulate, dry, granulate, obtained granule, incapsulates, obtains capsule.
Model case: xxx, man, 63 years old.Found before 2 years and suffer from pulmonary carcinoma, symptom is itching throat cough, coughs white expectorant, accompanies the blood streak once in a while, pain uncomfortable in chest, tachypnea, with back dull pain, after chemotherapeutic treatment, the state of an illness is improved not obvious, vertical phrenic lymph nodes enlargement, and two lung is dispersed in multiple transfer, household considers the condition of patient, abandons chemotherapy, select Chinese traditional treatment, time medical, tongue is dark red, yellow and thin fur, thready and rolling pulse, inappetence, lethargy.
Take the moistening the lung and resolving phlegm prescription capsule of the present embodiment gained treatment pulmonary carcinoma, adopt every day 2 times, each 4, with warm water delivery service, 20 days courses for the treatment of.After taking a course for the treatment of, cough disappears substantially, and hemoptysis disappears, alleviation of pain uncomfortable in chest is light, and after taking two courses for the treatment of, clinical symptoms is eliminated substantially, vertical phrenic lymph nodes is without enlargement, mass reduction, after taking four courses for the treatment of, two lungs are without obvious lump, without other new focuses, adhere to taking half a year, follow up a case by regular visits to after 2 years, patient body is in good condition.
embodiment 5the moistening the lung and resolving phlegm prescription for the treatment of pulmonary carcinoma, is prepared from (every part of 10g) primarily of following bulk drugs: Fructus Broussonetiae 11 parts, Folium Isatidis 13 parts, Angiopteris magna Ching (Angiopteris majuscula Ching) 12 parts, Herba Hedyotis Lanceae 10.5 parts, Herba Dianthi 12.5 parts, Herba Canscorae 12 parts, Radix Trichosanthis 9.5 parts, broken bowl palm foot sets 11 parts, Flos Farfarae 12 parts, Fructus Hibisci 10.5 parts, Herba Solani Lyrati 8 parts, Herba Lycianthis Biflorae 10 parts, Herba Galii Bungei 11.5 parts, Radix Sophorae Tonkinensis 11.5 parts, Herba monochoriae vaginalis 10 parts, Radix et Rhizoma Thalictri 7.5 parts, Radix Abelmoschi Sagittifolii 13.5 parts.
The preparation method of the moistening the lung and resolving phlegm prescription decoction for the treatment of pulmonary carcinoma is:
(1) get Fructus Broussonetiae and Fructus Hibisci roguing to clean, be placed in slow fire in frying pan and fry to buff, take out, mix thoroughly with Sucus Zingberis and saline, moistening 17 minutes, take out, dry;
(2) get Radix Trichosanthis and Herba Lycianthis Biflorae to clean, with bean curd with boiling, well-done rear taking-up, section, dries;
(3) Radix Sophorae Tonkinensis, Radix et Rhizoma Thalictri and Radix Abelmoschi Sagittifolii are cleaned, section, infiltrates 20 minutes with yellow wine, takes out, is placed in frying pan, together fries with Oryza glutinosa, and when frying Huang micro-to crude drug surface, take out, sieve removes Oryza glutinosa, dries;
(4) Angiopteris magna Ching (Angiopteris majuscula Ching), Herba Hedyotis Lanceae, Herba Dianthi, broken bowl palm foot tree, Herba Solani Lyrati and Herba monochoriae vaginalis roguing are cleaned, decocting in water (amount of water is 8 times of boiled crude drug quality) is together added with step (2) (3) made crude drug, big fire is boiled rear little fire and is decocted 30 minutes, Guan Huo, add Folium Isatidis, Herba Canscorae, Flos Farfarae and Herba Galii Bungei vexed 20 minutes, filter, collect filtrate;
(5) medicated powder is made in made for step (1) crude drug pulverizing, join in step (4) made filtrate, mix thoroughly, obtain decoction.
test example 1the clinical practice of the moistening the lung and resolving phlegm prescription (embodiment 5) of gained treatment pulmonary carcinoma of the present invention:
In November ,-2014 in June, 2012,240 routine Patients with Advanced Non-small Cell Lung Cancers are filtered out at 4 hospital's Respiratory Medicines, wherein women 92 example, male 148 example, age 40-65 year, year mean age (56.2 ± 5.1), wherein adenocarcinoma 164 example, scale cancer 76 example, III a phase 79 example, III b phase 137 example, IV phase 24 example.Get rid of and merge severe cardiac, liver, nephropathy and disease in the blood system and severe infections patient.
Patient is divided into two groups at random, experimental group 160 example and matched group 80 routine, two groups in sex, age, the course of disease, the state of an illness etc. without significant difference (
p> 0.05), there is comparability.Matched group adopts TP chemotherapy regimen, experimental group takes products obtained therefrom of the present invention on the basis of chemotherapy, and take every day twice (warm), each 200m1-300m1(adjusts to some extent depending on concrete condition), within 20 days, be a treatment cycle, treatment two all after date observe the curative effect continuously.Treatments period carries out Continuous Observation to two groups of patients, record symptom and change.
Curative effect situation criterion: complete incidence graph: all focuses disappear completely, and maintain more than 4 weeks; Partial rcsponse: the product summation minimizing of each focus maximum gauge and maximum perpendicular diameter thereof is more than or equal to 50%, and maintains more than 4 weeks; Stable: the achievement summation of each focus maximum gauge and maximum perpendicular diameter thereof reduces and is less than 50% or increase and be less than 25%; Progress: the product increase of at least one focus maximum gauge and maximum perpendicular diameter thereof is more than or equal to 25%, or occurs new focus.
Table 1 liang group patient treatment outcome
Therapeutic outcome is as shown in table 1: therefrom known, and the Overall response rate of experimental group is 95.1%, and the Overall response rate of matched group is 77.5%, two groups and compares, good compared with matched group of the therapeutic effect of experimental group.And after chemotherapy, experimental group patient occur untoward reaction symptom compared with matched group less and degree is lower.
The present invention selects Fructus Broussonetiae Zishen Qinggan, Folium Isatidis, Herba monochoriae vaginalis heat-clearing and toxic substances removing, Angiopteris magna Ching (Angiopteris majuscula Ching) damp eliminating diuresis, Herba Hedyotis Lanceae relieving cough and resolving phlegm, Herba Dianthi inducing diuresis for treating stranguria syndrome, Herba Canscorae cough-relieving pain relieving, Radix Trichosanthis detumescence and apocenosis, broken bowl palm foot tree removing stasis to stop bleeding, Flos Farfarae nourishing the lung to keep the adverse QI downward, Fructus Hibisci removing heat from the lung and dissipating phlegm, Herba Solani Lyrati clearing away heat-damp and promoting diuresis, Herba Lycianthis Biflorae expelling phlegm for arresting cough, Herba Galii Bungei clearing away heat and promoting diuresis, Radix Sophorae Tonkinensis detumescence sore-throat relieving, Radix et Rhizoma Thalictri eliminating fire and detoxication, Radix Abelmoschi Sagittifolii evacuation of pus is drawn out pus by applying a plaster to the affected part, plurality of raw materials medicine use together, can play the effects such as nourishing YIN and clearing away heat, expelling phlegm for arresting cough, lung heat clearing eliminating stagnation.
It should be pointed out that detailed description of the invention is the more representational example of the present invention, obvious technical scheme of the present invention is not limited to above-described embodiment, can also have a lot of distortion.Those of ordinary skill in the art, with the present invention clear and definite disclosed or according to undoubted the obtaining of the written description of file, the claimed scope of this patent all should be thought.
Claims (10)
1. treat the moistening the lung and resolving phlegm prescription of pulmonary carcinoma, it is characterized in that, be prepared from primarily of following bulk drugs, be mass parts: Fructus Broussonetiae 8-14, Folium Isatidis 10-16, Angiopteris magna Ching (Angiopteris majuscula Ching) 9-15, Herba Hedyotis Lanceae 7-14, Herba Dianthi 10-15, Herba Canscorae 8-16, Radix Trichosanthis 7-12, broken bowl palm foot tree 9-13, Flos Farfarae 10-14, Fructus Hibisci 9-12, Herba Solani Lyrati 6-10, Herba Lycianthis Biflorae 7-13, Herba Galii Bungei 9-14, Radix Sophorae Tonkinensis 8-15, Herba monochoriae vaginalis 6-14, Radix et Rhizoma Thalictri 5-10, Radix Abelmoschi Sagittifolii 11-16.
2. the moistening the lung and resolving phlegm prescription for the treatment of pulmonary carcinoma as claimed in claim 1, it is characterized in that, Fructus Broussonetiae 10-12, Folium Isatidis 12-14, Angiopteris magna Ching (Angiopteris majuscula Ching) 10-14, Herba Hedyotis Lanceae 9-12, Herba Dianthi 11-14, Herba Canscorae 10-14, Radix Trichosanthis 9-10, broken bowl palm foot tree 10-12, Flos Farfarae 11-13, Fructus Hibisci 10-11, Herba Solani Lyrati 7-9, Herba Lycianthis Biflorae 9-11, Herba Galii Bungei 10-13, Radix Sophorae Tonkinensis 10-13, Herba monochoriae vaginalis 8-12, Radix et Rhizoma Thalictri 6-9, Radix Abelmoschi Sagittifolii 13-14 is (preferred, Fructus Broussonetiae 11, Folium Isatidis 13, Angiopteris magna Ching (Angiopteris majuscula Ching) 12, Herba Hedyotis Lanceae 10.5, Herba Dianthi 12.5, Herba Canscorae 12, Radix Trichosanthis 9.5, broken bowl palm foot tree 11, Flos Farfarae 12, Fructus Hibisci 10.5, Herba Solani Lyrati 8, Herba Lycianthis Biflorae 10, Herba Galii Bungei 11.5, Radix Sophorae Tonkinensis 11.5, Herba monochoriae vaginalis 10, Radix et Rhizoma Thalictri 7.5, Radix Abelmoschi Sagittifolii 13.5).
3. the moistening the lung and resolving phlegm prescription of the treatment pulmonary carcinoma as described in as arbitrary in claim 1-2, it is characterized in that, be made into pharmaceutically acceptable decoction, its preparation method is:
(1) get Fructus Broussonetiae and Fructus Hibisci roguing to clean, be placed in slow fire in frying pan and fry to buff, take out, mix thoroughly with Sucus Zingberis and saline, moistening 15-20 minute (preferred, moistening 16-19 minute; Be more preferably, moistening 17 minutes), take out, dry;
(2) get Radix Trichosanthis and Herba Lycianthis Biflorae to clean, with bean curd with boiling, well-done rear taking-up, section, dries;
(3) Radix Sophorae Tonkinensis, Radix et Rhizoma Thalictri and Radix Abelmoschi Sagittifolii are cleaned, section, infiltrates 20 minutes with yellow wine, takes out, is placed in frying pan, together fries with Oryza glutinosa, and when frying Huang micro-to crude drug surface, take out, sieve removes Oryza glutinosa, dries;
(4) Angiopteris magna Ching (Angiopteris majuscula Ching), Herba Hedyotis Lanceae, Herba Dianthi, broken bowl palm foot tree, Herba Solani Lyrati and Herba monochoriae vaginalis roguing are cleaned, together add decocting in water with step (2) (3) made crude drug, big fire is boiled rear little fire and is decocted 25-35 minute (preferred, 27-33 minute decocted by little fire; Be more preferably, little fire decocts 30 minutes), Guan Huo, adds Folium Isatidis, Herba Canscorae, Flos Farfarae and Herba Galii Bungei vexed 20 minutes, filters, and collects filtrate;
(5) medicated powder is made in made for step (1) crude drug pulverizing, join in step (4) made filtrate, mix thoroughly, obtain decoction.
4. the preparation method of the moistening the lung and resolving phlegm prescription decoction for the treatment of pulmonary carcinoma as claimed in claim 3, is characterized in that, the 7-9 that step (4) amount of water is boiled crude drug quality is (preferred, amount of water is 8 times of boiled crude drug quality) doubly.
5. the moistening the lung and resolving phlegm prescription of the treatment pulmonary carcinoma as described in as arbitrary in claim 1-2, it is characterized in that, be made into pharmaceutically acceptable powder, its preparation method is:
(1) get Fructus Broussonetiae and Fructus Hibisci roguing to clean, be placed in slow fire in frying pan and fry to buff, take out, mix thoroughly with Sucus Zingberis and saline, moistening 15-20 minute (preferred, moistening 16-19 minute; Be more preferably, moistening 17 minutes), take out, dry;
(2) get Radix Trichosanthis and Herba Lycianthis Biflorae to clean, with bean curd with boiling, well-done rear taking-up, section, dries;
(3) Radix Sophorae Tonkinensis, Radix et Rhizoma Thalictri and Radix Abelmoschi Sagittifolii are cleaned, section, infiltrates 20 minutes with yellow wine, takes out, is placed in frying pan, together fries with Oryza glutinosa, and when frying Huang micro-to crude drug surface, take out, sieve removes Oryza glutinosa, dries;
(4) Folium Isatidis, Angiopteris magna Ching (Angiopteris majuscula Ching), Herba Hedyotis Lanceae, Herba Dianthi, Herba Canscorae, broken bowl palm foot tree, Flos Farfarae, Herba Solani Lyrati, Herba Galii Bungei and Herba monochoriae vaginalis roguing are cleaned, pulverize and sieve together with step (1) (2) (3) made crude drug, obtain powder.
6. the preparation method of the moistening the lung and resolving phlegm prescription powder for the treatment of pulmonary carcinoma as claimed in claim 5, it is characterized in that, step (4) was pulverized 200-280 mesh sieve and (preferably, was pulverized 220-260 mesh sieve; Be more preferably, pulverized 240 mesh sieves).
7. the moistening the lung and resolving phlegm prescription of the treatment pulmonary carcinoma as described in as arbitrary in claim 1-2, it is characterized in that, be made into pharmaceutically acceptable pill, its preparation method is:
(1) get Fructus Broussonetiae and Fructus Hibisci roguing to clean, be placed in slow fire in frying pan and fry to buff, take out, mix thoroughly with Sucus Zingberis and saline, moistening 15-20 minute (preferred, moistening 16-19 minute; Be more preferably, moistening 17 minutes), take out, dry;
(2) get Radix Trichosanthis and Herba Lycianthis Biflorae to clean, with bean curd with boiling, well-done rear taking-up, section, dries;
(3) Radix Sophorae Tonkinensis, Radix et Rhizoma Thalictri and Radix Abelmoschi Sagittifolii are cleaned, section, infiltrates 20 minutes with yellow wine, takes out, is placed in frying pan, together fries with Oryza glutinosa, and when frying Huang micro-to crude drug surface, take out, sieve removes Oryza glutinosa, dries;
(4) Folium Isatidis, Angiopteris magna Ching (Angiopteris majuscula Ching), Herba Hedyotis Lanceae, Herba Dianthi, Herba Canscorae, broken bowl palm foot tree, Flos Farfarae, Herba Solani Lyrati, Herba Galii Bungei and Herba monochoriae vaginalis roguing are cleaned, pulverize and sieve together with step (1) (2) (3) made crude drug, make medicated powder, add yellow wine and refined honey water, generally make ball, obtain pill.
8. the preparation method of the moistening the lung and resolving phlegm prescription pill for the treatment of pulmonary carcinoma as claimed in claim 7, it is characterized in that, step (4) was pulverized 100-160 mesh sieve and (preferably, was pulverized 120-140 mesh sieve; Be more preferably, pulverized 130 mesh sieves).
9. the moistening the lung and resolving phlegm prescription of the treatment pulmonary carcinoma as described in as arbitrary in claim 1-2, it is characterized in that, be made into pharmaceutically acceptable capsule, its preparation method is:
(1) get Fructus Broussonetiae and Fructus Hibisci roguing to clean, be placed in slow fire in frying pan and fry to buff, take out, mix thoroughly with Sucus Zingberis and saline, moistening 15-20 minute (preferred, moistening 16-19 minute; Be more preferably, moistening 17 minutes), take out, dry;
(2) get Radix Trichosanthis and Herba Lycianthis Biflorae to clean, with bean curd with boiling, well-done rear taking-up, section, dries;
(3) Radix Sophorae Tonkinensis, Radix et Rhizoma Thalictri and Radix Abelmoschi Sagittifolii are cleaned, section, infiltrates 20 minutes with yellow wine, takes out, is placed in frying pan, together fries with Oryza glutinosa, and when frying Huang micro-to crude drug surface, take out, sieve removes Oryza glutinosa, dries;
(4) Angiopteris magna Ching (Angiopteris majuscula Ching), Herba Hedyotis Lanceae, Herba Dianthi, broken bowl palm foot tree, Herba Solani Lyrati and Herba monochoriae vaginalis roguing are cleaned, decocting in water (amount of water is 8 times of boiled crude drug quality) is together added with step (2) (3) made crude drug, big fire is boiled rear little fire and is decocted 25-35 minute, add Folium Isatidis, Herba Canscorae, Flos Farfarae and Herba Galii Bungei vexed 20 minutes, filter, collect filtrate, filtering residue adds water and again decocts, merge twice filtrate, add and be condensed into thick paste;
(5) medicated powder is made in made for step (1) crude drug pulverizing, join in step (4) made thick paste, mix thoroughly, with sucrose and 10% starch slurry soft material, granulate, dry, granulate, obtained granule, incapsulates, obtains capsule.
10. the preparation method of the moistening the lung and resolving phlegm prescription capsule for the treatment of pulmonary carcinoma as claimed in claim 9, is characterized in that, step (4) big fire is boiled rear little fire and decocted little fire and decoct 27-33 minute (preferred, little fire decocts 30 minutes).
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| 王中奇: "《抗肿瘤中药临床应用手册 第1版》", 30 June 2013, 中国中医药出版社 * |
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| CN112190654A (en) * | 2020-11-04 | 2021-01-08 | 海南医学院 | Traditional Chinese medicine prescription for moistening lung and reducing phlegm and preparation method thereof |
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Address after: 336000, Jiangxi, Yuanzhou District, Xiu Xiu Jiang Road, No. 9, District, No. 2 building 3-501 Applicant after: Zhang Guangmin Address before: 250000 Ji'nan Province, Lixia District, Shandong by Road No. ten, No. 12372 Applicant before: Zhang Guangmin |
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| CB02 | Change of applicant information | ||
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Application publication date: 20151209 |
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| WD01 | Invention patent application deemed withdrawn after publication |