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CN104997995A - Traditional Chinese medicinal ointment for treating tinea pedis, and preparation method thereof - Google Patents

Traditional Chinese medicinal ointment for treating tinea pedis, and preparation method thereof Download PDF

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Publication number
CN104997995A
CN104997995A CN201510395605.XA CN201510395605A CN104997995A CN 104997995 A CN104997995 A CN 104997995A CN 201510395605 A CN201510395605 A CN 201510395605A CN 104997995 A CN104997995 A CN 104997995A
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ethanol
extraction
tinea pedis
water extract
chinese medicinal
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吴克
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Jiangsu Qilikang Skin Pharmaceutical Co Ltd
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Jiangsu Qilikang Skin Pharmaceutical Co Ltd
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Abstract

The invention belongs to the field of traditional Chinese medicines, and discloses a traditional Chinese medicinal ointment for treating tinea pedis, and a preparation method thereof. The traditional Chinese medicinal ointment for treating tinea pedis comprises, by weight, 5-10 parts of water extract of common cnidium fruit, 5-10 parts of water extract of Chinense Golden Larch Bark, 4-8 parts of water extract of Hainan Chaulmoogra Seed, 3-6 parts of 50wt% ethanol-containing water extract of Cortex Lycii, 4-8 parts of 50wt% ethanol-containing water extract of Rhizoma Cyperi, 6-12 parts of ethanol extract of Quisqualis indica, 5-10 parts of ethanol extract of Radix Peucedani, 6-10 parts of sodium stearate and 5-10 parts of glycerin. The preparation method comprises the following steps: drying, carrying out solvent extraction, separating, and concentrating to prepare the traditional Chinese medicinal ointment for treating tinea pedis. The traditional Chinese medicinal ointment for treating tinea pedis has the characteristics of good curative effect and low recurrence rate in the treatment of tinea pedis.

Description

A kind of Chinese medicinal ointment for the treatment of tinea pedis and preparation method thereof
Technical field
The invention belongs to the field of Chinese medicines, relate to a kind of Chinese medicinal ointment and preparation method thereof, particularly relate to a kind of Chinese medicinal ointment for the treatment of tinea pedis and preparation method thereof.
Background technology
Tinea pedis is by fungus-caused common skin diseases.Have the to be grown up summer sickness rate of tinea pedis of investigation display to reach 60%, particularly in south, because temperature is high and high humidity, sickness rate can be higher.Tinea pedis is a kind of conditionality infectious disease, often the bamboo telegraph because of shared washbasin, foot washing basin, foot towel, towel, slippers, socks, footwear and bathtub.Symptom is play vesicle, decortication or skin whitening between toe to wet soft, also erosion or pachyderma, coarse, cracking can be there is, and can spread to sole and the first edge of foot, play is itched, scratch companion local suppuration often, red and swollen, pain, inguinal lymphadenopathy, even forms the secondary infection such as shank erysipelas and cellulitis.The Chinese medicine formula for the treatment of tinea pedis is more, and as Radix Sophorae Flavescentis, Cortex Dictamni ` Herba Portulacae, each 30 grams of Herba Plantaginis, each 15 grams of Rhizoma Atractylodis, Cortex Phellodendri, decocts and wash 1-2 time every day.Apply to vesicle or when having infection and have good result.White Flos Impatientis 30 grams, Fructus Gleditsia 30 grams, 15 grams, Pericarpium Zanthoxyli, optional-kind, put into half jin of vinegar, soak after one day, in foot bath 20 minutes just before going to bed every night.Continuous treatment 7 days, diagonalization type has good effect.But tinea pedis can be effected a radical cure completely and the Chinese medicine do not recurred is considerably less.
Summary of the invention
The technical problem solved: tinea pedis is as a kind of persistent ailment, treatment tinea pedis good effect and the medicine do not recurred is less, most medicine curative effect in treatment tinea pedis is comparatively conventional, and after discontinuing medication, tinea pedis recurrence rate is higher, the object of the invention is openly a kind ofly to treat tinea pedis curative effect better and Chinese medicinal ointment not easily recurred and preparation method thereof.
Technical scheme: the invention discloses a kind of Chinese medicinal ointment for the treatment of tinea pedis and preparation method thereof, the Chinese medicinal ointment of described treatment tinea pedis comprises the composition of following weight parts:
Fructus Cnidii water extract 5-10 part,
Cortex Pseudolaricis water extract 5-10 part,
Semen Hydnocarpi water extract 4-8 part,
Cortex Lycii 50wt% ethanol-water extraction thing 3-6 part,
Rhizoma Cyperi 50wt% ethanol-water extraction thing 4-8 part,
Fructus Quisqualis ethanol extraction 6-12 part,
Radix Peucedani ethanol extraction 5-10 part,
Sodium stearate 6-10 part,
Glycerol 5-10 part.
Further, described a kind of Chinese medicinal ointment for the treatment of tinea pedis, comprises the composition of following weight parts:
Fructus Cnidii water extract 6-9 part,
Cortex Pseudolaricis water extract 6-9 part,
Semen Hydnocarpi water extract 5-7 part,
Cortex Lycii 50wt% ethanol-water extraction thing 4-5 part,
Rhizoma Cyperi 50wt% ethanol-water extraction thing 5-7 part,
Fructus Quisqualis ethanol extraction 7-11 part,
Radix Peucedani ethanol extraction 6-9 part,
Sodium stearate 7-9 part,
Glycerol 6-8 part.
Treat a preparation method for the Chinese medicinal ointment of tinea pedis, step is as follows:
(1) Fructus Cnidii, Cortex Pseudolaricis, Semen Hydnocarpi is got respectively, after drying, above-mentioned Chinese medicine is pulverized respectively, hot water is added respectively after pulverizing, separately carry out heated and stirred extraction, heated and stirred extracts rear centrifugalize, the supernatant of collected by centrifugation is separated vacuum concentration, prepares Fructus Cnidii water extract, Cortex Pseudolaricis water extract, Semen Hydnocarpi water extract respectively;
(2) grind after Cortex Lycii and Rhizoma Cyperi separate drying, add 50wt% ethanol water and carry out agitating heating extraction respectively, filter after extracting, filtering and collecting filter liquid, filtrate is separated vacuum concentration, is prepared as Cortex Lycii 50wt% ethanol-water extraction thing and Rhizoma Cyperi 50wt% ethanol-water extraction thing;
(3) Fructus Quisqualis and Radix Peucedani are dried, dry rear dehydrated alcohol and carry out heated and stirred extraction, leave standstill after extracting, filter after leaving standstill, get filtrate, filtrate is carried out vacuum concentration, after concentrated, be respectively Fructus Quisqualis ethanol extraction and Radix Peucedani ethanol extraction;
(4) Fructus Cnidii water extract 5-10 part, Cortex Pseudolaricis water extract 5-10 part, Semen Hydnocarpi water extract 4-8 part, Cortex Lycii 50wt% ethanol-water extraction thing 3-6 part, Rhizoma Cyperi 50wt% ethanol-water extraction thing 4-8 part, Fructus Quisqualis ethanol extraction 6-12 part, Radix Peucedani ethanol extraction 5-10 part, sodium stearate 6-10 part, glycerol 5-10 part is got by weight respectively, by above-mentioned various composition mixing, for treating the Chinese medicinal ointment of tinea pedis.
Described a kind of preparation method for the treatment of the Chinese medicinal ointment of tinea pedis, in step (1), heating-up temperature is 80 DEG C, and feed liquid total amount ratio is 1:7, and extraction time is 5h.
Described a kind of preparation method for the treatment of the Chinese medicinal ointment of tinea pedis, in step (2), heating-up temperature is 60 DEG C, and feed liquid total amount ratio is 1:10, and extraction time is 3h.
Described a kind of preparation method for the treatment of the Chinese medicinal ointment of tinea pedis, in step (3), heating-up temperature is 50 DEG C, and feed liquid total amount ratio is 1:12, and extraction time is 5h.
Described a kind of preparation method for the treatment of the Chinese medicinal ointment of tinea pedis, step (2) middle employing order number is that the filter cloth of more than 200 orders filters extracting solution.
Described a kind of preparation method for the treatment of the Chinese medicinal ointment of tinea pedis, vacuum concentration temperature is 50-60 DEG C.
Beneficial effect: in the Chinese medicinal ointment for the treatment of tinea pedis of the present invention, Extraction and separation has been carried out to the medicable composition of tool in Chinese medicine, obtain the ingredient that multiple treatment tinea pedis has remarkable effect, and above-mentioned composition is mixed into Chinese medicinal ointment, treatment tinea pedis has the advantages that therapeutic effect is good, not easily recur.To the cure rate of tinea pedis patient about 90%, and after treatment terminates, in half a year, recurrence rate is very low.
Detailed description of the invention
Embodiment 1
(1) Fructus Cnidii, Cortex Pseudolaricis, Semen Hydnocarpi is got respectively, after drying, above-mentioned Chinese medicine is pulverized respectively, hot water is added respectively after pulverizing, separately carry out heated and stirred extraction, heating-up temperature is 80 DEG C, and feed liquid total amount ratio is 1:7, extraction time is 5h, heated and stirred extracts rear centrifugalize, the supernatant of collected by centrifugation is separated vacuum concentration, prepares Fructus Cnidii water extract, Cortex Pseudolaricis water extract, Semen Hydnocarpi water extract respectively; (2) grind after Cortex Lycii and Rhizoma Cyperi separate drying, add 50wt% ethanol water and carry out agitating heating extraction respectively, heating-up temperature is 60 DEG C, feed liquid total amount ratio is 1:10, extraction time is 3h, filters, filtering and collecting filter liquid after extracting, filtrate is separated vacuum concentration, is prepared as Cortex Lycii 50wt% ethanol-water extraction thing and Rhizoma Cyperi 50wt% ethanol-water extraction thing; (3) Fructus Quisqualis and Radix Peucedani are dried, dry rear dehydrated alcohol and carry out heated and stirred extraction, heating-up temperature is 50 DEG C, feed liquid total amount ratio is 1:12, and extraction time is 5h, leaves standstill after extracting, filter after leaving standstill, get filtrate, filtrate is carried out vacuum concentration, after concentrated, be respectively Fructus Quisqualis ethanol extraction and Radix Peucedani ethanol extraction; (4) Fructus Cnidii water extract 5 parts, Cortex Pseudolaricis water extract 10 parts, Semen Hydnocarpi water extract 4 parts, Cortex Lycii 50wt% ethanol-water extraction thing 6 parts, Rhizoma Cyperi 50wt% ethanol-water extraction thing 8 parts, Fructus Quisqualis ethanol extraction 6 parts, Radix Peucedani ethanol extraction 10 parts, sodium stearate 6 parts, glycerol 10 parts is got by weight respectively, by above-mentioned various composition mixing, for treating the Chinese medicinal ointment of tinea pedis.
Embodiment 2
(1) Fructus Cnidii, Cortex Pseudolaricis, Semen Hydnocarpi is got respectively, after drying, above-mentioned Chinese medicine is pulverized respectively, hot water is added respectively after pulverizing, separately carry out heated and stirred extraction, heating-up temperature is 80 DEG C, and feed liquid total amount ratio is 1:7, extraction time is 5h, heated and stirred extracts rear centrifugalize, the supernatant of collected by centrifugation is separated vacuum concentration, prepares Fructus Cnidii water extract, Cortex Pseudolaricis water extract, Semen Hydnocarpi water extract respectively; (2) grind after Cortex Lycii and Rhizoma Cyperi separate drying, add 50wt% ethanol water and carry out agitating heating extraction respectively, heating-up temperature is 60 DEG C, feed liquid total amount ratio is 1:10, extraction time is 3h, filters, filtering and collecting filter liquid after extracting, filtrate is separated vacuum concentration, is prepared as Cortex Lycii 50wt% ethanol-water extraction thing and Rhizoma Cyperi 50wt% ethanol-water extraction thing; (3) Fructus Quisqualis and Radix Peucedani are dried, dry rear dehydrated alcohol and carry out heated and stirred extraction, heating-up temperature is 50 DEG C, feed liquid total amount ratio is 1:12, and extraction time is 5h, leaves standstill after extracting, filter after leaving standstill, get filtrate, filtrate is carried out vacuum concentration, after concentrated, be respectively Fructus Quisqualis ethanol extraction and Radix Peucedani ethanol extraction; (4) Fructus Cnidii water extract 10 parts, Cortex Pseudolaricis water extract 5 parts, Semen Hydnocarpi water extract 8 parts, Cortex Lycii 50wt% ethanol-water extraction thing 3 parts, Rhizoma Cyperi 50wt% ethanol-water extraction thing 4 parts, Fructus Quisqualis ethanol extraction 12 parts, Radix Peucedani ethanol extraction 5 parts, sodium stearate 10 parts, glycerol 5 parts is got by weight respectively, by above-mentioned various composition mixing, for treating the Chinese medicinal ointment of tinea pedis.
Embodiment 3
(1) Fructus Cnidii, Cortex Pseudolaricis, Semen Hydnocarpi is got respectively, after drying, above-mentioned Chinese medicine is pulverized respectively, hot water is added respectively after pulverizing, separately carry out heated and stirred extraction, heating-up temperature is 80 DEG C, and feed liquid total amount ratio is 1:7, extraction time is 5h, heated and stirred extracts rear centrifugalize, the supernatant of collected by centrifugation is separated vacuum concentration, prepares Fructus Cnidii water extract, Cortex Pseudolaricis water extract, Semen Hydnocarpi water extract respectively; (2) grind after Cortex Lycii and Rhizoma Cyperi separate drying, add 50wt% ethanol water and carry out agitating heating extraction respectively, heating-up temperature is 60 DEG C, feed liquid total amount ratio is 1:10, extraction time is 3h, filters, filtering and collecting filter liquid after extracting, filtrate is separated vacuum concentration, is prepared as Cortex Lycii 50wt% ethanol-water extraction thing and Rhizoma Cyperi 50wt% ethanol-water extraction thing; (3) Fructus Quisqualis and Radix Peucedani are dried, dry rear dehydrated alcohol and carry out heated and stirred extraction, heating-up temperature is 50 DEG C, feed liquid total amount ratio is 1:12, and extraction time is 5h, leaves standstill after extracting, filter after leaving standstill, get filtrate, filtrate is carried out vacuum concentration, after concentrated, be respectively Fructus Quisqualis ethanol extraction and Radix Peucedani ethanol extraction; (4) Fructus Cnidii water extract 6 parts, Cortex Pseudolaricis water extract 9 parts, Semen Hydnocarpi water extract 5 parts, Cortex Lycii 50wt% ethanol-water extraction thing 4 parts, Rhizoma Cyperi 50wt% ethanol-water extraction thing 7 parts, Fructus Quisqualis ethanol extraction 11 parts, Radix Peucedani ethanol extraction 6 parts, sodium stearate 9 parts, glycerol 8 parts is got by weight respectively, by above-mentioned various composition mixing, for treating the Chinese medicinal ointment of tinea pedis.
Embodiment 4
(1) Fructus Cnidii, Cortex Pseudolaricis, Semen Hydnocarpi is got respectively, after drying, above-mentioned Chinese medicine is pulverized respectively, hot water is added respectively after pulverizing, separately carry out heated and stirred extraction, heating-up temperature is 80 DEG C, and feed liquid total amount ratio is 1:7, extraction time is 5h, heated and stirred extracts rear centrifugalize, the supernatant of collected by centrifugation is separated vacuum concentration, prepares Fructus Cnidii water extract, Cortex Pseudolaricis water extract, Semen Hydnocarpi water extract respectively; (2) grind after Cortex Lycii and Rhizoma Cyperi separate drying, add 50wt% ethanol water and carry out agitating heating extraction respectively, heating-up temperature is 60 DEG C, feed liquid total amount ratio is 1:10, extraction time is 3h, filters, filtering and collecting filter liquid after extracting, filtrate is separated vacuum concentration, is prepared as Cortex Lycii 50wt% ethanol-water extraction thing and Rhizoma Cyperi 50wt% ethanol-water extraction thing; (3) Fructus Quisqualis and Radix Peucedani are dried, dry rear dehydrated alcohol and carry out heated and stirred extraction, heating-up temperature is 50 DEG C, feed liquid total amount ratio is 1:12, and extraction time is 5h, leaves standstill after extracting, filter after leaving standstill, get filtrate, filtrate is carried out vacuum concentration, after concentrated, be respectively Fructus Quisqualis ethanol extraction and Radix Peucedani ethanol extraction; (4) Fructus Cnidii water extract 9 parts, Cortex Pseudolaricis water extract 6 parts, Semen Hydnocarpi water extract 7 parts, Cortex Lycii 50wt% ethanol-water extraction thing 5 parts, Rhizoma Cyperi 50wt% ethanol-water extraction thing 5 parts, Fructus Quisqualis ethanol extraction 7 parts, Radix Peucedani ethanol extraction 9 parts, sodium stearate 7 parts, glycerol 6 parts is got by weight respectively, by above-mentioned various composition mixing, for treating the Chinese medicinal ointment of tinea pedis.
Embodiment 5
(1) Fructus Cnidii, Cortex Pseudolaricis, Semen Hydnocarpi is got respectively, after drying, above-mentioned Chinese medicine is pulverized respectively, hot water is added respectively after pulverizing, separately carry out heated and stirred extraction, heating-up temperature is 80 DEG C, and feed liquid total amount ratio is 1:7, extraction time is 5h, heated and stirred extracts rear centrifugalize, the supernatant of collected by centrifugation is separated vacuum concentration, prepares Fructus Cnidii water extract, Cortex Pseudolaricis water extract, Semen Hydnocarpi water extract respectively; (2) grind after Cortex Lycii and Rhizoma Cyperi separate drying, add 50wt% ethanol water and carry out agitating heating extraction respectively, heating-up temperature is 60 DEG C, feed liquid total amount ratio is 1:10, extraction time is 3h, filters, filtering and collecting filter liquid after extracting, filtrate is separated vacuum concentration, is prepared as Cortex Lycii 50wt% ethanol-water extraction thing and Rhizoma Cyperi 50wt% ethanol-water extraction thing; (3) Fructus Quisqualis and Radix Peucedani are dried, dry rear dehydrated alcohol and carry out heated and stirred extraction, heating-up temperature is 50 DEG C, feed liquid total amount ratio is 1:12, and extraction time is 5h, leaves standstill after extracting, filter after leaving standstill, get filtrate, filtrate is carried out vacuum concentration, after concentrated, be respectively Fructus Quisqualis ethanol extraction and Radix Peucedani ethanol extraction; (4) Fructus Cnidii water extract 7 parts, Cortex Pseudolaricis water extract 8 parts, Semen Hydnocarpi water extract 6 parts, Cortex Lycii 50wt% ethanol-water extraction thing 4 parts, Rhizoma Cyperi 50wt% ethanol-water extraction thing 6 parts, Fructus Quisqualis ethanol extraction 9 parts, Radix Peucedani ethanol extraction 7 parts, sodium stearate 8 parts, glycerol 7 parts is got by weight respectively, by above-mentioned various composition mixing, for treating the Chinese medicinal ointment of tinea pedis.
Comparative example 1
(1) Fructus Cnidii, Cortex Pseudolaricis, Semen Hydnocarpi is got respectively, after drying, above-mentioned Chinese medicine is pulverized respectively, hot water is added respectively after pulverizing, separately carry out heated and stirred extraction, heating-up temperature is 80 DEG C, and feed liquid total amount ratio is 1:7, extraction time is 5h, heated and stirred extracts rear centrifugalize, the supernatant of collected by centrifugation is separated vacuum concentration, prepares Fructus Cnidii water extract, Cortex Pseudolaricis water extract, Semen Hydnocarpi water extract respectively; (2) Fructus Quisqualis and Radix Peucedani are dried, dry rear dehydrated alcohol and carry out heated and stirred extraction, heating-up temperature is 50 DEG C, feed liquid total amount ratio is 1:12, and extraction time is 5h, leaves standstill after extracting, filter after leaving standstill, get filtrate, filtrate is carried out vacuum concentration, after concentrated, be respectively Fructus Quisqualis ethanol extraction and Radix Peucedani ethanol extraction; (3) Fructus Cnidii water extract 5 parts, Cortex Pseudolaricis water extract 10 parts, Semen Hydnocarpi water extract 4 parts, Fructus Quisqualis ethanol extraction 6 parts, Radix Peucedani ethanol extraction 10 parts, sodium stearate 6 parts, glycerol 10 parts is got by weight respectively, by above-mentioned various composition mixing, for treating the Chinese medicinal ointment of tinea pedis.
Comparative example 2
(1) Fructus Cnidii, Cortex Pseudolaricis, Semen Hydnocarpi is got respectively, after drying, above-mentioned Chinese medicine is pulverized respectively, hot water is added respectively after pulverizing, separately carry out heated and stirred extraction, heating-up temperature is 80 DEG C, and feed liquid total amount ratio is 1:7, extraction time is 5h, heated and stirred extracts rear centrifugalize, the supernatant of collected by centrifugation is separated vacuum concentration, prepares Fructus Cnidii water extract, Cortex Pseudolaricis water extract, Semen Hydnocarpi water extract respectively; (2) grind after Cortex Lycii and Rhizoma Cyperi separate drying, add 50wt% ethanol water and carry out agitating heating extraction respectively, heating-up temperature is 60 DEG C, feed liquid total amount ratio is 1:10, extraction time is 3h, filters, filtering and collecting filter liquid after extracting, filtrate is separated vacuum concentration, is prepared as Cortex Lycii 50wt% ethanol-water extraction thing and Rhizoma Cyperi 50wt% ethanol-water extraction thing; (3) Fructus Cnidii water extract 5 parts, Cortex Pseudolaricis water extract 10 parts, Semen Hydnocarpi water extract 4 parts, Cortex Lycii 50wt% ethanol-water extraction thing 6 parts, Rhizoma Cyperi 50wt% ethanol-water extraction thing 8 parts, sodium stearate 6 parts, glycerol 10 parts is got by weight respectively, by above-mentioned various composition mixing, for treating the Chinese medicinal ointment of tinea pedis.
Tinea pedis patient is divided into 7 groups, and often organize patient smears embodiment and comparative example every day Chinese medicinal ointment in affected part, the time of smearing is 30 days, and after 30 days, observe the cure rate of patient and the percentage ratio of recurrence in half a year, result is as follows:
Embodiment 1 Embodiment 2 Embodiment 3 Embodiment 4 Embodiment 5 Comparative example 1 Comparative example 2
Cure rate 90% 90% 92% 91% 95% 76% 74%
In half a year, compositely proportional is as follows:
Embodiment 1 Embodiment 2 Embodiment 3 Embodiment 4 Embodiment 5 Comparative example 1 Comparative example 2
Relapse rate 6% 5% 3% 4% 1% 17% 19%

Claims (8)

1. treat a Chinese medicinal ointment for tinea pedis, it is characterized in that the Chinese medicinal ointment of described treatment tinea pedis comprises the composition of following weight parts:
Fructus Cnidii water extract 5-10 part,
Cortex Pseudolaricis water extract 5-10 part,
Semen Hydnocarpi water extract 4-8 part,
Cortex Lycii 50wt% ethanol-water extraction thing 3-6 part,
Rhizoma Cyperi 50wt% ethanol-water extraction thing 4-8 part,
Fructus Quisqualis ethanol extraction 6-12 part,
Radix Peucedani ethanol extraction 5-10 part,
Sodium stearate 6-10 part,
Glycerol 5-10 part.
2. a kind of Chinese medicinal ointment for the treatment of tinea pedis according to claim 1, is characterized in that the Chinese medicinal ointment of described treatment tinea pedis comprises the composition of following weight parts:
Fructus Cnidii water extract 6-9 part,
Cortex Pseudolaricis water extract 6-9 part,
Semen Hydnocarpi water extract 5-7 part,
Cortex Lycii 50wt% ethanol-water extraction thing 4-5 part,
Rhizoma Cyperi 50wt% ethanol-water extraction thing 5-7 part,
Fructus Quisqualis ethanol extraction 7-11 part,
Radix Peucedani ethanol extraction 6-9 part,
Sodium stearate 7-9 part,
Glycerol 6-8 part.
3. treat a preparation method for the Chinese medicinal ointment of tinea pedis, it is characterized in that, the preparation method step of the Chinese medicinal ointment of described treatment tinea pedis is as follows:
(1) Fructus Cnidii, Cortex Pseudolaricis, Semen Hydnocarpi is got respectively, after drying, above-mentioned Chinese medicine is pulverized respectively, hot water is added respectively after pulverizing, separately carry out heated and stirred extraction, heated and stirred extracts rear centrifugalize, the supernatant of collected by centrifugation is separated vacuum concentration, prepares Fructus Cnidii water extract, Cortex Pseudolaricis water extract, Semen Hydnocarpi water extract respectively;
(2) grind after Cortex Lycii and Rhizoma Cyperi separate drying, add 50wt% ethanol water and carry out agitating heating extraction respectively, filter after extracting, filtering and collecting filter liquid, filtrate is separated vacuum concentration, is prepared as Cortex Lycii 50wt% ethanol-water extraction thing and Rhizoma Cyperi 50wt% ethanol-water extraction thing;
(3) Fructus Quisqualis and Radix Peucedani are dried, dry rear dehydrated alcohol and carry out heated and stirred extraction, leave standstill after extracting, filter after leaving standstill, get filtrate, filtrate is carried out vacuum concentration, after concentrated, be respectively Fructus Quisqualis ethanol extraction and Radix Peucedani ethanol extraction;
(4) Fructus Cnidii water extract 5-10 part, Cortex Pseudolaricis water extract 5-10 part, Semen Hydnocarpi water extract 4-8 part, Cortex Lycii 50wt% ethanol-water extraction thing 3-6 part, Rhizoma Cyperi 50wt% ethanol-water extraction thing 4-8 part, Fructus Quisqualis ethanol extraction 6-12 part, Radix Peucedani ethanol extraction 5-10 part, sodium stearate 6-10 part, glycerol 5-10 part is got by weight respectively, by above-mentioned various composition mixing, for treating the Chinese medicinal ointment of tinea pedis.
4. a kind of preparation method for the treatment of the Chinese medicinal ointment of tinea pedis according to claim 3, is characterized in that, in described preparation method step (1), heating-up temperature is 80 DEG C, and feed liquid total amount ratio is 1:7, and extraction time is 5h.
5. a kind of preparation method for the treatment of the Chinese medicinal ointment of tinea pedis according to claim 3, is characterized in that, in described preparation method step (2), heating-up temperature is 60 DEG C, and feed liquid total amount ratio is 1:10, and extraction time is 3h.
6. a kind of preparation method for the treatment of the Chinese medicinal ointment of tinea pedis according to claim 3, is characterized in that, in described preparation method step (3), heating-up temperature is 50 DEG C, and feed liquid total amount ratio is 1:12, and extraction time is 5h.
7. a kind of preparation method for the treatment of the Chinese medicinal ointment of tinea pedis according to claim 3, is characterized in that, described preparation method step (2) middle employing order number is that the filter cloth of more than 200 orders filters extracting solution.
8. a kind of preparation method for the treatment of the Chinese medicinal ointment of tinea pedis according to claim 3, is characterized in that, in described preparation method, vacuum concentration temperature is 50-60 DEG C.
CN201510395605.XA 2015-07-08 2015-07-08 Traditional Chinese medicinal ointment for treating tinea pedis, and preparation method thereof Pending CN104997995A (en)

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