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CN104983674A - External use drug for quickly relieving itching, eliminating swelling and rash, and resisting mosquito and insect bites - Google Patents

External use drug for quickly relieving itching, eliminating swelling and rash, and resisting mosquito and insect bites Download PDF

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Publication number
CN104983674A
CN104983674A CN201510372571.2A CN201510372571A CN104983674A CN 104983674 A CN104983674 A CN 104983674A CN 201510372571 A CN201510372571 A CN 201510372571A CN 104983674 A CN104983674 A CN 104983674A
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CN
China
Prior art keywords
parts
bite
erythema
mosquito
used medicine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201510372571.2A
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Chinese (zh)
Inventor
李燃
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wuhan Langqi Biological Science & Technology Co Ltd
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Wuhan Langqi Biological Science & Technology Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Priority to CN201510372571.2A priority Critical patent/CN104983674A/en
Publication of CN104983674A publication Critical patent/CN104983674A/en
Pending legal-status Critical Current

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  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

The invention discloses an external use drug for quickly relieving itching, eliminating swelling and rash, and resisting mosquito and insect bites. The external use drug is prepared by mixing the following raw materials in parts by weight: 10 to 150 parts of menthol, 10 to 150 parts of borneol, 5 to 30 parts of ethylparaben, 40-300 parts of natural gel, 500-1000 parts of ethanol, 200-500 parts of glycerin and 0-500 parts of pure water. According to the external use drug provided by the invention, the natural gel is used as a carrier, the natural menthol is used as the main raw material, some natural polymeric substances are matched, and a percutaneous absorption process is adopted to enable the active ingredients to penetrate the skin, so that the effects of relieving itching and eliminating swelling and rash are achieved; the manner of applying the drug externally is adopted; after the drug is applied to the meridian points of human bodies, the active ingredients run with meridian circulation, and the effects of removing heat and resisting mosquito and insect bites are remarkable; in addition, the drug does not enter the digestive system of human bodies, therefore, no harm or toxic or side effect is caused; the external use drug is a safe, and environment-friendly product with the functions of relieving itching, eliminating swelling and rash, and resisting mosquito and insect bites.

Description

The external used medicine of Quick itch stopping, elimination redness, erythema and anti-mosquito bite and insect bite
Technical field
The present invention relates to external used medicine technical field, be specifically related to a kind of Quick itch stopping, eliminate the external used medicine of redness, erythema and anti-mosquito bite and insect bite.
Background technology
Current known floral water is all be Main Ingredients and Appearance by Mentholum, ethanol, essence, due to the difference of kind, or has and adds dimethyl phthalate, Moschus, Calculus Bovis etc.Its major function is all emphasize anophelifuge, mosquito-proof, miliaria of dispelling, antipruritic, eliminate red and swollen, erythema, and plays the mainly dimethyl phthalate of mosquito-repelling function, and its composition is pesticide, is large-arealy for a long time sprayed on skin, has and has no side effect or problem controversial at present.And after really running into mosquito bite, or epidemic disease summer heat, the various pains that miliaria causes, swell, itching there is no effect.
Medicine of the present invention is in body surface medication, does not have drug damages, can Reusability not by time restriction, directly spread upon skin surface not only can Quick itch stopping, eliminate red and swollen, erythema, effectively can also prevent mosquito bite and insect bite.
Summary of the invention
Object of the present invention is exactly the deficiency that will overcome the existence of above-mentioned prior art, the external used medicine of a kind of Quick itch stopping, elimination redness, erythema and prevention mosquito bite and insect bite is provided, spread upon and got final product Quick itch stopping by mosquito bite place, eliminate red and swollen, erythema, if spread upon skin surface effectively can prevent mosquito bite and insect bite, and can repeated multiple timesly smear, have no side effect.
For achieving the above object, the invention provides a kind of Quick itch stopping, the external used medicine of eliminating red and swollen, erythema and anti-mosquito bite and insect bite that do not add any farm chemical ingredients, it is mixed according to parts by weight proportioning by following component raw material, and the parts by weight of each component raw material are as follows:
Mentholum 10-150 part, Borneolum Syntheticum 10-150 part, ethyl hydroxybenzoate 5-30 part, Native Gel 40-300 part, ethanol 500-1000 part, glycerol 200-500 part, pure water 0-500 part.
Preferably, this external used medicine is mixed according to parts by weight proportioning by following component raw material, and the parts by weight of each component raw material are as follows:
Mentholum 50-150 part, Borneolum Syntheticum 50-150 part, ethyl hydroxybenzoate 5-30 part, Native Gel 40-300 part, ethanol 500-1000 part, glycerol 200-500 part, pure water 0-500 part.
Preferably, this external used medicine is mixed according to parts by weight proportioning by following component raw material, and the parts by weight of each component raw material are as follows:
Mentholum 50 parts, Borneolum Syntheticum 50 parts, ethyl hydroxybenzoate 25 parts, Native Gel 300 parts, ethanol 800 parts, glycerol 500 parts, pure water 0-500 part.
Preferably, the dosage form of this external used medicine described is patch.Patch is pasted onto on skin, and medicine can produce whole body or local action.Patch can be used for intact skin surface, and also can be used for has illness or incomplete skin surface.
Preferably, the dosage form of this external used medicine described is gel.
Preferably, the dosage form of this external used medicine described is pearl agent.Open bottle cap, ball down, is placed in be smeared back and forth by the position of mosquito bite and gets final product Quick itch stopping, eliminates red and swollen, erythema by bottleneck.Each position is repeated multiple times smear after can eliminate redness, erythema etc.
Preferably, described pure water is deionized water or distilled water.
Preferably, described Native Gel is the mixture of xanthan gum and guar gum.
Borneolum Syntheticum is had one's ideas straightened out refreshment, the loose poison of heat clearing away, and Borneolum Syntheticum through mucous membrane, subcutaneous tissue all easily absorb, is combined with glucuronic acid in vivo get rid of afterwards external; The volatile loose wind heat of Mentholum, can be used for skin or mucosa produces refrigerant sense to alleviate discomfort and pain; Ethyl hydroxybenzoate uses as antibacterial; Glycerol has moisture-keeping function, nice and cool lubrication after medicine external; Ethanol is good organic solvent, and has stronger osmosis, and Mentholum, Borneolum Syntheticum are dissolved in ethanol, can strengthen antiinflammatory, antibacterial action.
The invention has the beneficial effects as follows:
First, Raw Borneolum Syntheticum of the present invention is had one's ideas straightened out refreshment, the loose poison of heat clearing away, the volatile loose wind heat of Mentholum, antiinflammatory, utilize two kinds of composition synergism, with pure natural Mentholum for primary raw material, coordinate the polymer substance that some are natural, use Transdermal absorption technique, make active ingredient permeate subcutaneous, antipruritic, eliminate redness, erythema, antiinflammatory, antibacterial effect are better;
The second, Native Gel is good point subrack, is uniformly distributed by effective ingredient in the carrier, makes drug action evenly lasting;
3rd, the present invention adopts external mode of smearing, by being applied in health by mosquito bite place, can Quick itch stopping, eliminate red and swollen, erythema, and without any injury or toxic and side effects, be a safe, green, environmental protection antipruritic, eliminate redness, erythema product.
4th, the present invention spreads upon skin surface effectively can prevent mosquito bite and insect bite.
Detailed description of the invention
Below in conjunction with specific embodiment, the present invention is described in further detail.
Embodiment 1
An external used medicine for Quick itch stopping, elimination redness, erythema and anti-mosquito bite and insect bite, it is mixed according to parts by weight proportioning by following component raw material, and the parts by weight of each component raw material are as follows:
Mentholum 50 parts, Borneolum Syntheticum 50 parts, ethyl hydroxybenzoate 25 parts, xanthan gum 150 parts, guar gum 150 parts, ethanol 800 parts, glycerol 500 parts, pure water 0 part.
The dosage form adopting the present embodiment to obtain medicine is patch.
Embodiment 2
An external used medicine for Quick itch stopping, elimination redness, erythema and anti-mosquito bite and insect bite, it is mixed according to parts by weight proportioning by following component raw material, and the parts by weight of each component raw material are as follows:
Mentholum 10 parts, Borneolum Syntheticum 10 parts, ethyl hydroxybenzoate 5 parts, xanthan gum 50, guar gum 50, ethanol 800 parts, glycerol 500 parts, pure water 50 parts.
The dosage form adopting the present embodiment to obtain medicine is patch.
Embodiment 3
An external used medicine for Quick itch stopping, elimination redness, erythema and anti-mosquito bite and insect bite, it is mixed according to parts by weight proportioning by following component raw material, and the parts by weight of each component raw material are as follows:
Mentholum 10 parts, Borneolum Syntheticum 10 parts, ethyl hydroxybenzoate 5 parts, xanthan gum 150, guar gum 150, ethanol 800 parts, glycerol 500 parts, pure water 100 parts.
The dosage form adopting the present embodiment to obtain medicine is gel.
Embodiment 4
An external used medicine for Quick itch stopping, elimination redness, erythema and anti-mosquito bite and insect bite, it is mixed according to parts by weight proportioning by following component raw material, and the parts by weight of each component raw material are as follows:
Mentholum 150 parts, Borneolum Syntheticum 150 parts, ethyl hydroxybenzoate 20 parts, xanthan gum 100, guar gum 100, part, ethanol 500 parts, glycerol 500 parts, pure water 100 parts.
The dosage form adopting the present embodiment to obtain medicine is gel.
Embodiment 5
An external used medicine for Quick itch stopping, elimination redness, erythema and anti-mosquito bite and insect bite, it is mixed according to parts by weight proportioning by following component raw material, and the parts by weight of each component raw material are as follows:
Mentholum 100 parts, Borneolum Syntheticum 100 parts, ethyl hydroxybenzoate 5 parts, xanthan gum 20, guar gum 20, ethanol 800 parts, glycerol 500 parts, pure water 250 parts.
The dosage form adopting the present embodiment to obtain medicine is pearl agent.
Embodiment 6
An external used medicine for Quick itch stopping, elimination redness, erythema and anti-mosquito bite and insect bite, it is mixed according to parts by weight proportioning by following component raw material, and the parts by weight of each component raw material are as follows:
Mentholum 150 parts, Borneolum Syntheticum 100 parts, ethyl hydroxybenzoate 10 parts, xanthan gum 50, guar gum 50 ethanol 800 parts, glycerol 500 parts, pure water 350 parts.
The dosage form adopting the present embodiment to obtain medicine is pearl agent.
Clinical trial one:
Select 90 white mice, depilation process, be divided into three groups at random and make marks, often organize 30 white mice, test group 30 white mice smear antipruritic, the external used medicine of eliminating red and swollen, erythema and anti-mosquito bite and insect bite of the present invention, matched group 30 white mice smear floral water, and blank group 30 white mice do not smear any medicine.
Under 90 white mice are placed on the experimental situation of mosquito, after one hour, observe white mice epidermis red packet, red point and the situation that tickles.
Concrete therapeutic effect is as following table:
Curative effect judging standard: under 90 white mice are placed on the experimental situation of mosquito, observes white mice epidermis red packet, red point and the situation that tickles after one hour.
From table, the effect that the present invention is used for anti-mosquito bite and insect bite is very remarkable.
The present invention does not add any harmful substance, adopt external mode of smearing, by being applied in by mosquito bite place, antipruritic, eliminate red and swollen, erythema effect is remarkable fast, anti-mosquito bite and insect bite successful, and do not enter the digested system of body, without any injury or toxic and side effects, be antipruritic, the product of eliminating red and swollen, erythema and prevention mosquito bite and insect bite of a safe, green, environmental protection.
The above is the preferred embodiment of the present invention, but is not limited thereto.

Claims (8)

1. an external used medicine for Quick itch stopping, elimination redness, erythema and anti-mosquito bite and insect bite, is characterized in that: it is mixed according to parts by weight proportioning by following component raw material, and the parts by weight of each component raw material are as follows:
Mentholum 10-150 part, Borneolum Syntheticum 10-150 part, ethyl hydroxybenzoate 5-30 part, Native Gel 40-300 part, ethanol 500-1000 part, glycerol 200-500 part, pure water 0-500 part.
2. the external used medicine of Quick itch stopping according to claim 1, elimination redness, erythema and anti-mosquito bite and insect bite, is characterized in that: it is mixed according to parts by weight proportioning by following component raw material, and the parts by weight of each component raw material are as follows:
Mentholum 50-150 part, Borneolum Syntheticum 50-150 part, ethyl hydroxybenzoate 5-30 part, Native Gel 40-300 part, ethanol 500-1000 part, glycerol 200-500 part, pure water 0-500 part.
3. the external used medicine of Quick itch stopping according to claim 1, elimination redness, erythema and anti-mosquito bite and insect bite, is characterized in that: it is mixed according to parts by weight proportioning by following component raw material, and the parts by weight of each component raw material are as follows:
Mentholum 50 parts, Borneolum Syntheticum 50 parts, ethyl hydroxybenzoate 25 parts, Native Gel 300 parts, ethanol 800 parts, glycerol 500 parts, pure water 0-500 part.
4. the external used medicine of Quick itch stopping according to claims 1 to 3, elimination redness, erythema and anti-mosquito bite and insect bite, is characterized in that: the dosage form of this external used medicine described is patch.
5. the external used medicine of Quick itch stopping according to claims 1 to 3, elimination redness, erythema and anti-mosquito bite and insect bite, is characterized in that: the dosage form of this external used medicine described is gel.
6. the external used medicine of Quick itch stopping according to claims 1 to 3, elimination redness, erythema and anti-mosquito bite and insect bite, is characterized in that: the dosage form of this external used medicine described is pearl agent.
7. the external used medicine of Quick itch stopping according to claims 1 to 3, elimination redness, erythema and anti-mosquito bite and insect bite, is characterized in that: described pure water is deionized water or distilled water.
8. the external used medicine of Quick itch stopping according to claims 1 to 3, elimination redness, erythema and anti-mosquito bite and insect bite, is characterized in that: described Native Gel is the mixture of xanthan gum and guar gum.
CN201510372571.2A 2015-06-30 2015-06-30 External use drug for quickly relieving itching, eliminating swelling and rash, and resisting mosquito and insect bites Pending CN104983674A (en)

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CN201510372571.2A CN104983674A (en) 2015-06-30 2015-06-30 External use drug for quickly relieving itching, eliminating swelling and rash, and resisting mosquito and insect bites

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Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108114025A (en) * 2018-03-01 2018-06-05 遵义医学院 A kind of hydrogel Antipruritic adhesive plaster of pure plant
CN108703975A (en) * 2018-08-30 2018-10-26 黄汝怡 A kind of liniment treated poisonous insect and bitten
CN108785379A (en) * 2018-06-26 2018-11-13 苏州尚宜佳生物科技有限公司 One kind gram vertical refrigerant release membranes of boron sieve and preparation method thereof
CN111436397A (en) * 2020-02-07 2020-07-24 湖南师范大学 Method for constructing animal model for simulating mosquito bite symptoms
CN115252704A (en) * 2022-06-10 2022-11-01 广西中医药大学 Yao medicine composition for treating skin diseases and preparation method thereof

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102048817A (en) * 2010-12-21 2011-05-11 东莞市腾业实业有限公司 Itch relieving and detoxifying liquid for mosquito and insect biting
CN102319142A (en) * 2011-05-26 2012-01-18 谭波 Antipyretic gel

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102048817A (en) * 2010-12-21 2011-05-11 东莞市腾业实业有限公司 Itch relieving and detoxifying liquid for mosquito and insect biting
CN102319142A (en) * 2011-05-26 2012-01-18 谭波 Antipyretic gel

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
王元凤等译: "《功能性食品碳水化合物》", 30 April 2009, 中国轻工业出版社 *

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108114025A (en) * 2018-03-01 2018-06-05 遵义医学院 A kind of hydrogel Antipruritic adhesive plaster of pure plant
CN108785379A (en) * 2018-06-26 2018-11-13 苏州尚宜佳生物科技有限公司 One kind gram vertical refrigerant release membranes of boron sieve and preparation method thereof
CN108703975A (en) * 2018-08-30 2018-10-26 黄汝怡 A kind of liniment treated poisonous insect and bitten
CN111436397A (en) * 2020-02-07 2020-07-24 湖南师范大学 Method for constructing animal model for simulating mosquito bite symptoms
CN111436397B (en) * 2020-02-07 2021-11-30 湖南师范大学 Method for constructing animal model for simulating mosquito bite symptoms
CN115252704A (en) * 2022-06-10 2022-11-01 广西中医药大学 Yao medicine composition for treating skin diseases and preparation method thereof

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Application publication date: 20151021