CN104960006A - Automatic anti-toxin gel cutting machine, imager and gel cutting method of anti-toxin automatic gel cutting machine - Google Patents
Automatic anti-toxin gel cutting machine, imager and gel cutting method of anti-toxin automatic gel cutting machine Download PDFInfo
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- CN104960006A CN104960006A CN201510300790.XA CN201510300790A CN104960006A CN 104960006 A CN104960006 A CN 104960006A CN 201510300790 A CN201510300790 A CN 201510300790A CN 104960006 A CN104960006 A CN 104960006A
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- cover cap
- gel
- imager
- cutting
- grid
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Abstract
The invention relates to an automatic anti-toxin gel cutting machine and an imager. The automatic anti-toxin gel cutting machine comprises a base plate and a cold cutter. The base plate is square and is provided with a first grid. The cold cutter is a cover lid. A second grid is arranged on the top of the cover lid. The first grid is the same with the second grid. Cutting needles or cutting pieces are arranged on the cover lid. The base plate is matched with the cover lid. The anti-toxin gel cutting machine is arranged in the imager. The invention further provides a cutting method of the anti-toxin gel cutting machine. The automatic anti-toxin gel cutting machine, the imager and the cutting method of the anti-toxin automatic gel cutting machine have the advantages that the shape and the position of gel to be cut can be determined through the grid on the base plate, gel cutting is completed in the imager under the coordination of the cover lid, a human body is prevented from making contact with ultraviolet rays and ED colorants during gel cutting, and therefore the harm of the ultraviolet rays and the ED colorants to the human body is avoided.
Description
Technical field
The present invention relates to a kind of gelatin cutting device, specifically, is the automatic gel cutting device of a kind of gas defence and imager and rubber tapping method thereof.
Background technology
The most frequently used at present technology of biotechnology just belongs to round pcr, research gene molecule all will be from here on, what the checking of PCR primer was the most basic runs sample about agarose gel electrophoresis exactly, carry out electrophoretic separation by the size of the gene molecule amount of amplification, form the band of different molecular weight size gene.Gene band after separation needs just can see by after imager imaging, and gel wants imaging then must have EB coloring agent and Ultraviolet radiation.EB coloring agent is a kind of super-sensitive fluorescent dye, and excite with standard 302nm ultraviolet light transmission instrument and radiate orange red signal, but EB has certain carcinogenicity, can volatilize, health is easily poisoned in laboratory.Although invented nontoxic EB substituting agent abroad now, expensive effect has not had EB good, therefore EB or main flow.Have now special gel imaging instrument, the built-in ultraviolet lamp in the inside, because EB needs the imaging of ultraviolet ability, so need out uviol lamp when imaging, imager present at present is all directly observed by computer and is avoided the irradiation of ultraviolet to people.
Although now this technology people is little contact these two murder by poisoning, also having a necessary step in the research of some gene molecule, is exactly " rubber tapping is reclaimed ", so-called rubber tapping reclaim exactly the gel phase run through in requisition for the glue of molecular weight cut down.Because the Ago-Gel running through electrophoresis is still transparent blob of viscose, only under the condition at ultraviolet irradiation after EB dyeing, just can observe the gene of the molecular weight required for oneself at which particular location, so the craft rubber tapping that current rubber tapping is all artificial exposure to be carried out under ultraviolet light, EB is also easy to diffusion and is detrimental to health in atmosphere.
Therefore, a kind of device that ultraviolet and EB harmful to human, safety and precise can be avoided to tap rubber is needed.About such device, yet there are no report.
Summary of the invention
The object of the invention is for deficiency of the prior art, a kind of gas defence gel cutting device is provided.
The present invention again one object be that a kind of imager being provided with gel cutting device is provided.
The another object of the present invention provides a kind of rubber tapping method.
For achieving the above object, the technical scheme that the present invention takes is:
A kind of gas defence gel cutting device, comprise chassis and cold cut cutter, described chassis is provided with the first grid.
Described cold cut cutter is cover cap, the top of described cover cap is provided with the second grid, the first described grid is identical with the second grid, on described cover cap, the Nodes of the second grid is provided with through hole, in through hole, slippage is connected with cutting needle, the overall rectangular array-like of described cutting needle, described cover cap and chassis match.
Described cold cut cutter is cover cap, the top of described cover cap is provided with the second grid, the first described grid is identical with the second grid, the inside top of described cover cap is provided with articulamentum, articulamentum is provided with cutting blade, described cutting blade is banded, and be made up of flexible metallic material, described cover cap and chassis match.
Described cold cut cutter is automatic gas cutting machine, described automatic gas cutting machine is provided with base, the first travel mechanism, the second travel mechanism, controller and cutter head, described base is provided with guide rail, the first described travel mechanism is connected with base sliding by guide rail, the second described travel mechanism and the first travel mechanism are slidably connected, the output of described controller is connected with the first travel mechanism, the second travel mechanism, the input of controller is connected with computer, described cutter head is fixed in the second travel mechanism, and described chassis is positioned on base.
For realizing above-mentioned second object, the technical scheme that the present invention takes is:
A kind of imager, is provided with gas defence gel cutting device in described imager.
Described gas defence gel cutting device is chassis and cover cap, the inner upper of described imager is provided with slideway, slideway is provided with slide device, cylinder is connected with below described slide device, be connected with the cover cap of gas defence gel cutting device below cylinder, the wall box of imager is provided with port, and described passage port is provided with sealed door.
Described gas defence gel cutting device is chassis and automatic gas cutting machine.
For realizing above-mentioned 3rd object, the technical scheme that the present invention takes is:
A kind of rubber tapping method, described rubber tapping method is, gel is placed on chassis, then imager imaging is put into, the picture that one comprises gene beam shapes and the first grid is taken by computer, to photograph and picture, the cutting needle at corresponding node place on cover cap headed in cover cap or is bent to by cutting blade shape that picture records and be fixed on corresponding position on articulamentum, finally cover cap being buckled on chassis and can completing rubber tapping.
A kind of rubber tapping method, described rubber tapping method is, gel is placed on chassis, then imaging in imager, the picture that one comprises gene beam shapes and the first grid is taken by computer, according to position and the shape of required cutting gel, the cutting needle at corresponding node place on cover cap headed in cover cap or is bent to by cutting blade shape that picture records and be fixed on corresponding position on articulamentum, then cover cap is fixed on the cylinder below slide device, by slideway, cover cap is slided to directly over chassis, under air cylinder driven, cover cap presses down, cover cap covers on chassis, complete cutting.
A kind of rubber tapping method, described rubber tapping method is be provided with automatic gas cutting machine in imager, and gel is in imager after imaging, by computer, the information of the shape needing cutting is sent to controller, controller controls cutter head by the first travel mechanism, the second travel mechanism and cuts.
The invention has the advantages that:
The present invention can determine shape and the position of the gel of required cutting by the grid on chassis, coordinate cover cap to complete rubber tapping in imager, and when avoiding rubber tapping, people contacts with ultraviolet, ED, thus avoids ultraviolet, ED to the harm of human body.
Accompanying drawing explanation
Accompanying drawing 1 is the structural representation on chassis.
Accompanying drawing 2 is structural representations of cutting needle cover cap.
Accompanying drawing 3 is structural representations of cutting blade cover cap.
Accompanying drawing 4 is structural representations of imager.
Accompanying drawing 5 is structural representations of automatic gas cutting machine.
Detailed description of the invention
Below in conjunction with accompanying drawing, detailed description of the invention provided by the invention is elaborated.
The Reference numeral related in accompanying drawing and part as follows:
1. chassis 11. first grid
2. cover cap 21. second grid
22. through hole 23. cutting needles
24. cutting blade 3. imagers
31. sealed door 4. slideways
41. slide device 42. cylinders
51. base 52. guide rails
53. first travel mechanisms of travel mechanism 54. second
55. controller 56. blades.
Embodiment 1
Please refer to Fig. 1, Fig. 1 is the structural representation on chassis.Described chassis 1 is that square, described chassis 1 is provided with the first grid 11.
Gel after dyeing is placed on chassis 1 and together puts into imager, observed by computer after opening ultraviolet lamp, shoot the photo containing the first grid 11 in gene beam shapes and chassis 1, to photograph and picture, the cold instrument of artificial use cuts on the chassis 1 having grid 11 simultaneously.
Embodiment 2
Please refer to Fig. 2, Fig. 2 is the structural representation of cutting needle cover cap.The Nodes that described cover cap 2 is provided with the second grid 21, second grid 21 is provided with through hole 22, and in through hole 22, slippage is connected with cutting needle 23, the overall rectangular array-like of described cutting needle 23.
Gel is placed on chassis 1, then put into imager imaging, take the picture that comprises gene beam shapes and the first grid 11, to photograph and picture by computer, the cutting needle 23 at corresponding node place on cover cap 2 is headed in cover cap 2, finally cover cap 2 is buckled on chassis 1 and can completes rubber tapping.
Embodiment 3
Please refer to Fig. 3, the structural representation of Fig. 3 cutting blade cover cap.Described cover cap 2 is provided with the second grid 21, and the inside top of cover cap 2 is provided with articulamentum (not shown), and articulamentum is provided with cutting blade 24, and described cutting blade 24 is banded, is made up of flexible metallic material.
Gel is placed on chassis 1, then imager imaging is put into, the picture that one comprises gene beam shapes and the first grid 11 is taken by computer, to photograph and picture, cutting blade 24 is bent to the shape that picture records, and be fixed on corresponding position on articulamentum, finally cover cap 2 is buckled on chassis 1 and can completes rubber tapping.
Embodiment 4
Please refer to Fig. 4, Fig. 4 is the structural representation of imager.The wall box of described imager 3 is provided with port (not shown), passage port is provided with sealed door 31, the inner upper of described imager 3 is provided with slideway 4, slideway is provided with slide device 41, described slide device 41 is provided with cylinder 42, one end of described cylinder 42 is connected with cover cap 2, and described cover cap 2 is cutting needle cover cap or cutting blade cover cap.
By gel in imager 3 after imaging, the picture that one comprises gene beam shapes and the first grid 11 is taken by computer, according to position and the shape of required cutting gel, the cutting needle 23 at corresponding node place on cover cap 2 is headed in cover cap 2 or cutting blade 24 is bent to shape that picture records and be fixed on corresponding position on articulamentum, then cover cap 2 is fixed on the cylinder 42 below slide device 41, afterwards cover cap 2 and cylinder 42 are together slided in imager, and close port by sealed door 31, coloring agent is prevented to be diffused into outside imager 3, when cover cap 2 slides to directly over chassis 1, cylinder 42 drives cover cap 2 to press down, cover cap 2 covers on chassis 1, complete cutting.
Embodiment 5
Please refer to Fig. 5, Fig. 5 is the structural representation of automatic gas cutting machine.Described automatic gas cutting machine is provided with travel mechanism 54 of base 51, first travel mechanism 53, second, controller 55 and cutter head 56, described base 51 is provided with guide rail 52, the first described travel mechanism 53 is slidably connected by guide rail 52 and base 51, the second described travel mechanism 54 and the first travel mechanism 53 are slidably connected, the output of described controller 55 is connected with the first travel mechanism 54 of travel mechanism 53, second, the input of controller 55 is connected with computer, and described cutter head 56 is fixed in the second travel mechanism 54.
Gel after dyeing is placed on chassis 1 and then puts into imager, observed by computer after opening ultraviolet lamp, shoot the photo containing the first grid 11 in gene beam shapes and chassis 1 simultaneously, in imager, automatic gas cutting machine is installed, by computer, the information of the shape needing cutting is sent to controller, controller 55 can control the first travel mechanism 54 of travel mechanism 53, second all around respectively and move, thus control cutter head 56 cuts.
Embodiment 6
Gel after dyeing is placed on chassis 1 and together puts into imager, observed by computer after opening ultraviolet lamp, shoot the photo containing the first grid 11 in gene beam shapes and chassis 1 simultaneously, to photograph and picture, determine the shape needing to cut gel; Then gel and chassis 1 are transferred on the base 51 of automatic gas cutting machine; The information of the shape needing cutting is input in computer, controls automatic gas cutting machine by computer and carry out cutting gel.
Embodiment 1-3 and embodiment 6 accurately determine the position of gene band by the first grid 11 when cutting gel, no longer need afterwards to cut under ultraviolet light, avoid the irradiation of ultraviolet to human body; The now effect of coloring agent reaches, can first just coloring agent remove after cut again, avoid the harm of noxious material.
The rubber tapping process of embodiment 4-5 completes in imager 3, avoids Ultraviolet radiation on human body, and imager 3 keeps airtight always simultaneously, prevents EB coloring agent from diffusing to harmful to human in air.
It should be noted that, the first described grid 11 and the second grid 22 adopt identical specification, mesh-density is larger, the precision of cutting is higher, when the node of grid is abundant, directly cuts out the colloid of needs by cutting needle, and when grid node is less, first tentatively can determine cutting profile by cutting needle 23, then artificially be cut by instrument, now cutting needle 23 act as location; The wall box of described imager is provided with port, be convenient to cover cap 2 and cylinder 42 slides in imager, described port is sealed by sealed door 31 under normal conditions, its role is to prevent dust etc. from entering into imager, avoid the coloring agent when tapping rubber to be diffused into imager outside, hermetically-sealed construction also can adopt flexible Self-enclosing simultaneously.
The above is only the preferred embodiment of the present invention; it should be pointed out that for those skilled in the art, under the prerequisite not departing from the inventive method; can also make some improvement and supplement, these improve and supplement and also should be considered as protection scope of the present invention.
Claims (10)
1. a gas defence gel cutting device, is characterized in that, comprise chassis and cold cut cutter, described chassis is provided with the first grid.
2. gas defence gel cutting device according to claim 1, it is characterized in that, described cold cut cutter is cover cap, the top of described cover cap is provided with the second grid, the first described grid is identical with the second grid, and on described cover cap, the Nodes of the second grid is provided with through hole, and in through hole, slippage is connected with cutting needle, the overall rectangular array-like of described cutting needle, described cover cap and chassis match.
3. gas defence gel cutting device according to claim 1, it is characterized in that, described cold cut cutter is cover cap, the top of described cover cap is provided with the second grid, and the first described grid is identical with the second grid, and the inside top of described cover cap is provided with articulamentum, articulamentum is provided with cutting blade, described cutting blade is banded, and be made up of flexible metallic material, described cover cap and chassis match.
4. gas defence gel cutting device according to claim 1, it is characterized in that, described cold cut cutter is automatic gas cutting machine, described automatic gas cutting machine is provided with base, first travel mechanism, second travel mechanism, controller and cutter head, described base is provided with guide rail, the first described travel mechanism is connected with base sliding by guide rail, the second described travel mechanism and the first travel mechanism are slidably connected, the output of described controller and the first travel mechanism, second travel mechanism connects, the input of controller is connected with computer, described cutter head is fixed in the second travel mechanism, described chassis is positioned on base.
5. an imager, is characterized in that, is provided with the arbitrary described gas defence gel cutting device of claim 1-4 in described imager.
6. imager according to claim 5, it is characterized in that, described gas defence gel cutting device is the gas defence gel cutting device described in Claims 2 or 3, the inner upper of described imager is provided with slideway, slideway is provided with slide device, is connected with cylinder below described slide device, is connected below cylinder with the cover cap of gas defence gel cutting device, the wall box of imager is provided with port, and described passage port is provided with sealed door.
7. imager according to claim 5, is characterized in that, described gas defence gel cutting device is gas defence gel cutting device according to claim 4.
8. the rubber tapping method of the gas defence gel cutting device described in Claims 2 or 3, it is characterized in that, gel is placed on chassis, then imager imaging is put into, the picture that one comprises gene beam shapes and the first grid is taken by computer, to photograph and picture, the cutting needle at corresponding node place on cover cap headed in cover cap or is bent to by cutting blade shape that picture records and be fixed on corresponding position on articulamentum, finally cover cap being buckled on chassis and can completing rubber tapping.
9. the rubber tapping method of imager according to claim 6, it is characterized in that, gel is placed on chassis, then imaging in imager, the picture that one comprises gene beam shapes and the first grid is taken by computer, according to position and the shape of required cutting gel, the cutting needle at corresponding node place on cover cap headed in cover cap or is bent to by cutting blade shape that picture records and be fixed on corresponding position on articulamentum, then cover cap is fixed on the cylinder below slide device, by slideway, cover cap is slided to directly over chassis, under air cylinder driven, cover cap presses down, cover cap covers on chassis, complete cutting.
10. the rubber tapping method of imager according to claim 7, it is characterized in that, in imager, automatic gas cutting machine is installed, gel is in imager after imaging, by computer, the information of the shape needing cutting is sent to controller, controller controls cutter head by the first travel mechanism, the second travel mechanism and cuts.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510300790.XA CN104960006B (en) | 2015-06-04 | 2015-06-04 | A kind of rubber tapping method of gas defence gel cutter |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510300790.XA CN104960006B (en) | 2015-06-04 | 2015-06-04 | A kind of rubber tapping method of gas defence gel cutter |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN104960006A true CN104960006A (en) | 2015-10-07 |
| CN104960006B CN104960006B (en) | 2018-01-16 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201510300790.XA Expired - Fee Related CN104960006B (en) | 2015-06-04 | 2015-06-04 | A kind of rubber tapping method of gas defence gel cutter |
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| Country | Link |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN108527462A (en) * | 2018-04-28 | 2018-09-14 | 福建农林大学 | A kind of high-cleanness, high based on L formula running gel rubber knifes cuts gluing method |
| CN110161170A (en) * | 2018-02-14 | 2019-08-23 | 广东医科大学 | Sample processing device and bioactivity screening system containing the device |
| CN110161171A (en) * | 2018-02-14 | 2019-08-23 | 广东医科大学 | A kind of method and its application with bioactive ingredients in planar chromatograph ingredient microarray high flux screening complicated ingredient |
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| CN110161171A (en) * | 2018-02-14 | 2019-08-23 | 广东医科大学 | A kind of method and its application with bioactive ingredients in planar chromatograph ingredient microarray high flux screening complicated ingredient |
| CN108527462A (en) * | 2018-04-28 | 2018-09-14 | 福建农林大学 | A kind of high-cleanness, high based on L formula running gel rubber knifes cuts gluing method |
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| Publication number | Publication date |
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| CN104960006B (en) | 2018-01-16 |
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Granted publication date: 20180116 |