CN104886252A - Compound traditional Chinese medicine antialcoholic yogurt and preparation technology thereof - Google Patents

Abstract

The invention relates to compound traditional Chinese medicine antialcoholic yogurt and a preparation technology thereof. The antialcoholic yogurt is prepared from yogurt and traditional Chinese medicine extractive juice in the weight ratio being 8:1, wherein the traditional Chinese medicine extractive juice comprises kudzuvine roots, fructus lycii, bamboo shavings, lesser galangal rhizome, ginkgo leaves, poria cocos, tangerine peel, lightyellow sophora roots, chrysanthemum, white hyacinth beans, dandelion, cape jasmine fruit, Chinese date, pawpaw, rice-grain sprouts, largehead atractylodes rhizome, rhizoma corydalis, cassia barks, liquorice, asiatic pennywort herb, Chinese angelica, mulberry fruit and hovenia acerba which work together and complement one another. Metabolism of alcohol in a human body can be accelerated, excretion of the alcohol can be prompted, and the endurance capacity of the human body to alcohol is enhanced.

Description

A compound traditional Chinese medicine hangover yoghurt and its preparation process

technical field

The invention belongs to the technical field of health care products, and in particular relates to a compound traditional Chinese medicine hangover yoghurt and a preparation process thereof.

Background technique

Drinking a small amount of alcohol can promote blood circulation and dredge collaterals, but excessive drinking can cause toxic damage to the liver, nervous system, and reproductive system of the human body. In recent years, due to the increase in social needs and life pressure, the number of alcohol consumers in my country has increased, and according to statistics, it has exceeded 500 million people. Alcoholism and alcoholism have become public health problems in our country. The liver is the largest gland in the human body. It plays a very important role in human metabolism, bile production, detoxification, blood coagulation, immunity, heat production, and regulation of water and electrolytes. Generally speaking, there are two main pathogenic factors that cause liver damage. One is liver inflammation caused by pathogenic microorganisms such as virus infection, such as hepatitis A and hepatitis B. The other type is chemical liver damage, which is caused by various toxic substances, such as alcohol in food, chemical poisons in the environment, and certain drugs, which cause damage to the liver.

The classification and function of anti-alcoholic drugs in the market: 1. Chemical drugs: mostly stimulants, vitamins and amino acids, which play the role of promoting alcohol decomposition and sobering up, and have little effect on organ damage and chronic poisoning caused by alcohol. 2. Enzyme preparation: hangover capsules containing acetaldehyde dehydrogenase and traditional Chinese medicine can quickly decompose acetaldehyde and absorb alcohol, but the price is expensive. 3. Traditional Chinese medicine preparations: Traditional Chinese medicine has a long history of hangover. It adopts holistic view and syndrome differentiation, and has a therapeutic effect on both acute and chronic alcoholism.

Traditional Chinese medicine believes that alcohol is a hot and humid thing, so the general anti-alcohol prescription uses more heat-clearing and damp-reducing medicinal materials. Similar products on the market often use this dialectical principle. According to modern pharmacological research, it is explained as accelerating the metabolism of ethanol in the body, enhancing ethanol tolerance, etc. aspect. Alcohol is a hot and poisonous product, and excessive drinking will damage the spleen, stomach, liver and gallbladder and cause diseases. The pathogenesis can be summarized as: deficiency of spleen and stomach qi, internal resistance of phlegm dampness, internal stagnation of water dampness, disharmony of qi and blood, stagnation of qi and blood stasis, etc. Among them, alcohol damages the liver and spleen, gathers dampness and produces phlegm, and is the key to the disease; while insufficient body endowment and weak spleen and stomach are the root of the disease. China is rich in medicinal plant resources, and there are many anti-alcoholic prescriptions in ancient my country, and there are corresponding formulas for various symptoms caused by drinking. According to ancient books, there are many kinds of prescriptions or treatment methods. Only the incomplete statistics of "Taiping Shenghui Prescription", "Shi Yi De Xiao Fang", "Pu Ji Fang" and "Yi Fang Lei Ju" are not enough. There are more than 150 kinds of alcohol and anti-alcoholic prescriptions, of which anti-alcoholic prescriptions account for 90% and alcoholic prescriptions account for 10%. Today, some scholars in our country have studied the anti-alcoholic ability of ancient national prescriptions such as Gehuajie Hangover Decoction, Jiuxianle, Ganzhong Wine, Shigao Decoction and Wuzi Yanzong Pills, and some people have developed Hangover Oral Liquid and Hangover Tea And hangover functional preparations.

Nowadays, there are all kinds of hangover medicines, but all medicines have their disadvantages:

1. Drugs can irritate the gastrointestinal mucosa and have certain toxic and side effects on the human body, especially western medicines for anti-alcoholism. The present invention is used as a food hangover hangover instead of a drug hangover hangover, and can reduce the stimulating effect of the medicine on the human body;

2. On the one hand, yogurt can alleviate the irritation of the drug on the gastrointestinal tract, and on the other hand, the probiotic fermented yogurt itself has a hangover effect, so that it can reduce the damage of the drug to the body and make the hangover effect better;

3. Traditional Chinese medicine tastes bitter and difficult to swallow, but this product has a smooth and refreshing taste, which is easier to be accepted by people.

Contents of the invention

Most of the anti-alcoholic products are medicines at present, but few are used as food. Due to the various disadvantages of drug hangover, it is very important to find a way to hangover with food. For this reason, many anti-alcohol products have appeared at home and abroad, such as: natural grass anti-alcohol tea: using kudzu root, kudzu flower, wilting puerpera, ginkgo leaf, and ginkgo flavonoids as raw materials, respectively washed, dried, crushed, fried, and finally mixed and stirred production. Dashengcao hangover tea can effectively change the production of acetaldehyde dehydrogenase in the human body, thereby alleviating people's discomfort caused by drunkenness; Ruilaixing hangover hangover and Shenyi health tea: it uses the wild edible plant kudzu root, Its main ingredient is extracted scientifically from Henan famous tea Xinyang Maojian tea. Its anti-alcohol mechanism is as follows: after entering the human body, it stimulates the liver P-450 enzyme system to increase its transformation activity by 4-5 times, thereby adding alcohol detoxification by degradation transformation.

In the present invention, traditional Chinese medicines are compounded and added to yogurt in a certain proportion, which can fundamentally solve the problem, avoiding the problem that western medicines can’t understand the essence, and Chinese medicines are compounded and used to increase their anti-alcoholic effect, and the taste is added to yogurt It is easier to be accepted by people; in addition, relying on the hangover and buffering effect of yogurt itself, it can increase the effect of hangover while protecting the gastrointestinal mucosa of the human body. In addition, probiotics are added during yogurt fermentation to maintain the balance of flora in the human body.

The purpose of the present invention is to provide a drug preparation with the effect of rapidly reducing the alcohol concentration in blood for the purpose of relieving alcohol, diuresis and protecting the liver after drinking in an appropriate amount for people who drink too much. The solution of the present invention is based on the process of alcohol absorption and metabolism in the body of modern biological science combined with the dialectical treatment of drunkenness in the traditional medicine of the motherland. According to the theory of traditional Chinese medicine, according to the comprehensive sobering up idea of slowing down absorption, strengthening metabolism, accelerating excretion, and promoting recovery, it follows safety Nutrition, comprehensive prevention and control, technologically advanced and economically reasonable development principles.

For realizing the object of the invention, the technical scheme that the present invention adopts is as follows:

A hangover-relief yoghurt with compound traditional Chinese medicine, which is characterized in that the hangover-relief yoghurt is prepared from yoghurt and traditional Chinese medicine dipping juice at a weight ratio of 8:1.

The traditional Chinese medicine dipping juice is prepared from the following raw materials in weight ratio:

40 parts of kudzu root, 40 parts of medlar, 35 parts of Zhuru, 35 parts of galangal, 35 parts of ginkgo leaf,

Poria cocos 35 parts, tangerine peel 35 parts, flavescens 30 parts, chrysanthemum 30 parts, white lentils 30 parts,

30 parts of dandelion, 30 parts of gardenia, 25 parts of jujube, 25 parts of papaya, 25 parts of grain buds,

20 parts of Atractylodes macrocephala, 20 parts of Yanhusuo, 20 parts of cinnamon, 20 parts of licorice, 20 parts of Centella asiatica,

15 parts of angelica, 15 parts of mulberry fruit, and 10 parts of Hovenia dulcis.

Its preparation method of Chinese medicine steeping juice of the present invention is specifically as follows:

1) Take each bulk drug and set aside;

2) Mix kudzu root, bamboo rutabaga, galangal, poria cocos, tangerine peel, chrysanthemum, gardenia, jujube, grain bud, atractylodes macrocephala, and angelica, add 5 times the weight of water to boil, then simmer for 1 hour, filter and collect Filtrate and filter residue; add 3 times the weight of water to the filter residue, boil with strong fire, then decoct with slow fire for 30 minutes, filter and collect the filtrate; combine the above two filtrates to obtain liquid A;

3) Take the remaining raw materials, mix, add twice the weight of 75% ethanol to soak for 1 hour, then reflux for 2 hours, collect the extract, filter to obtain liquid B;

4) Mix and stir liquid A and liquid B evenly to obtain Chinese medicine infusion juice.

According to the weight ratio of 8:1, the yoghurt and traditional Chinese medicine soaking juice are mixed and homogenized for 2 minutes to obtain the traditional Chinese medicine hangover yoghurt of the present invention.

This product is suitable for both men and women. It is mainly used for hangover relief. Drink 200ml-400ml.

The components of the medicine of the present invention all use natural Chinese medicine raw materials, which are easy to prepare, have a wide range of medicine sources, and are low in cost. They follow the principles of prescription medication in traditional Chinese medicine. The amount can be doubled without adverse effects. This product can reduce the body's absorption of alcohol, and at the same time accelerate the metabolism of alcohol in the body, increase the excretion of alcohol, and enhance the body's tolerance to alcohol; taking it after drunkenness can improve and treat headaches, dizziness, and nausea caused by drunkenness And other discomfort symptoms, play a hangover effect. The curative effect is remarkable and reliable, and the application prospect is broad.

Detailed ways

Example 1

A hangover-relief yoghurt with compound traditional Chinese medicine, which is characterized in that the hangover-relief yoghurt is prepared from yoghurt and traditional Chinese medicine dipping juice at a weight ratio of 8:1.

The traditional Chinese medicine dipping juice is prepared from the following raw materials in weight ratio:

40 parts of kudzu root, 40 parts of medlar, 35 parts of Zhuru, 35 parts of galangal, 35 parts of ginkgo leaf,

Poria cocos 35 parts, tangerine peel 35 parts, flavescens 30 parts, chrysanthemum 30 parts, white lentils 30 parts,

30 parts of dandelion, 30 parts of gardenia, 25 parts of jujube, 25 parts of papaya, 25 parts of grain buds,

20 parts of Atractylodes macrocephala, 20 parts of Yanhusuo, 20 parts of cinnamon, 20 parts of licorice, 20 parts of Centella asiatica,

15 parts of angelica, 15 parts of mulberry fruit, and 10 parts of Hovenia dulcis.

Its preparation method of Chinese medicine steeping juice of the present invention is specifically as follows:

1) Take each bulk drug and set aside;

2) Mix kudzu root, bamboo rutabaga, galangal, poria cocos, tangerine peel, chrysanthemum, gardenia, jujube, grain bud, atractylodes macrocephala, and angelica, add 5 times the weight of water to boil, then simmer for 1 hour, filter and collect Filtrate and filter residue; add 3 times the weight of water to the filter residue, boil with strong fire, then decoct with slow fire for 30 minutes, filter and collect the filtrate; combine the above two filtrates to obtain liquid A;

3) Take the remaining raw materials, mix, add twice the weight of 75% ethanol to soak for 1 hour, then reflux for 2 hours, collect the extract, filter to obtain liquid B;

4) Mix and stir liquid A and liquid B evenly to obtain Chinese medicine infusion juice.

According to the weight ratio of 8:1, the yoghurt and traditional Chinese medicine soaking juice are mixed and homogenized for 2 minutes to obtain the traditional Chinese medicine hangover yoghurt of the present invention.

This product is suitable for both men and women. It is mainly used for hangover relief. Drink 200ml-400ml.

Example 2

Anti-alcoholic ability experiment of mice

Take 40 mice, both male and female, and raise them in the laboratory for 1 day. After fasting for 5 hours, they were weighed and marked and randomly divided into model group (blank control group) and Example 1 group of the present invention. Firstly, the dosage of 0.25ml/20g of wine was given by intragastric administration, and the yogurt prepared in Example 1 was given immediately after the wine was given, and the blank control group was given distilled water. Taking the loss of righting reflex as the sleep index, the tolerance time (time from ethanol gavage to the loss of righting reflex) was calculated, and the results are shown in Table 1 below:

Table 1

group Number of cases Not drunk (only) drunk sleep (only) Tolerance time min model group 20 0 20 2.4±1.5 G 20 13 7 20.3±1.2

It can be seen from the above table 1 that the traditional Chinese medicine hangover yogurt of the present invention can significantly enhance the tolerance time of mice, and the hangover effect is remarkable.

Example 3

(1) Clinical data:

Randomly select male alcohol drinkers, according to the nature of their usual work, select people with more social activities, age range 26-55 years old, no other diseases, obvious alcohol fatigue, headache, fatigue, dizziness and other symptoms after drinking. A total of 98 people were tested.

(2) Test method:

Set the crowd who do not drink the Chinese medicine anti-alcohol yoghurt of the present invention as a blank control group, and record the duration of the symptoms of discomfort after drinking in the blank control group.

The experimental group drank 200 ml of Chinese medicine anti-alcohol yoghurt prepared in Example 1 of the present invention after drinking, and the amount of alcohol consumed was equivalent to that of the previous headache.

The above two groups, 49 people in each group.

(3) Judgment criteria for curative effect:

Significant effect: Compared with the blank control group, the duration of headache, dizziness and fatigue symptoms is reduced by 50%;

Effective: Compared with the blank control group, the duration of headache, dizziness and fatigue symptoms is reduced by 30%;

Ineffective: Compared with the blank control group, there is no obvious improvement in the reduction of the duration of headache, dizziness, and fatigue symptoms;

(4) Experimental results

Observe the uncomfortable symptoms of each group of subjects after drinking the composition of the present invention, record the time, and compare the time of the blank group.

Result: After taking the Chinese medicine hangover yoghurt prepared in Example 1, symptoms such as drowsiness, dizziness, headache, and nausea were obviously relieved, and there were 29 people who were markedly effective, 17 people were effective, and 3 people were ineffective. Efficiency: 94%.

Example 4

Typical example

Mr. Liu, due to work, often drank a lot of alcohol, often drinking to dizziness, nausea and vomiting after drinking, burning sensation and bloating in the stomach after drinking. After drinking, take 200-300ml of traditional Chinese medicine hangover yoghurt prepared in Example 1, drowsiness, dizziness, and headache are significantly relieved, and the stomach no longer has the burning sensation and bloating feeling after drinking, and the spirit of the second day after drinking can be completely recovered. back to normal.

The above enumerated are only the best specific embodiments of the present invention. Obviously, the present invention is not limited to the above embodiments, and many variations are possible. All deformations that can be directly derived or associated by those skilled in the art from the content disclosed in the present invention should be considered as the protection scope of the present invention.

Claims (3)

1. A compound Chinese medicine hangover yogurt, characterized in that the hangover yogurt is prepared from yogurt and traditional Chinese medicine dipping juice according to a weight ratio of 8:1; The traditional Chinese medicine dipping juice is prepared from the following raw materials in weight ratio: 40 parts of kudzu root, 40 parts of medlar, 35 parts of Zhuru, 35 parts of galangal, 35 parts of ginkgo leaf, Poria cocos 35 parts, tangerine peel 35 parts, flavescens 30 parts, chrysanthemum 30 parts, white lentils 30 parts, 30 parts of dandelion, 30 parts of gardenia, 25 parts of jujube, 25 parts of papaya, 25 parts of grain buds, 20 parts of Atractylodes macrocephala, 20 parts of Yanhusuo, 20 parts of cinnamon, 20 parts of licorice, 20 parts of Centella asiatica, 15 parts of angelica, 15 parts of mulberry fruit, and 10 parts of Hovenia dulcis. 2. The hangover-relief yogurt according to claim 1, characterized in that, said traditional Chinese medicine dipping juice is prepared according to the following method: 1) Weigh each raw material according to the weight ratio, and set aside; 2) Mix kudzu root, bamboo, galangal, poria cocos, tangerine peel, chrysanthemum, gardenia, jujube, grain bud, atractylodes macrocephala, angelica, add 5 times the weight of water to boil, then simmer for 1 hour, filter Collect the filtrate and filter residue; add 3 times the weight of water to the filter residue, boil with strong fire, then simmer for 30 minutes, filter and collect the filtrate; combine the above two filtrates to obtain liquid A; 3) Take the remaining raw materials, mix, add twice the weight of 75% ethanol to soak for 1 hour, then reflux for 2 hours, collect the extract, filter to obtain liquid B; 4) Mix liquid A and liquid B, stir evenly to get Chinese medicine infusion juice. 3. The hangover-relieving yoghurt described in claims 1-2 is used for hangover-relieving.