CN1048409C - Capsule for protecting liver and eliminating tumor - Google Patents

Abstract

The present invention discloses a capsule for mainly treating liver cancer, protecting the liver and eliminating tumors, which has better therapeutic effect on breast cancer and gastric cancer simultaneously. The capsule is prepared from about 20 Chinese herbal medicines and has the characteristics of short treating course and no toxic or side effect.

Description

Building lotus capsule

The invention belongs to compound Chinese medicinal preparation, be used for the treatment of tumor disease, be particularly useful for treating hepatocarcinoma, simultaneously gastric cancer and breast carcinoma are also had better curative effect.

Hepatocarcinoma is " king in the cancer ", is one of modal malignant tumor in the world, and mortality rate is higher, and the medicine to the treatment ideal of this disease is very few at present.Hepatocarcinoma is that tangible buildup is in liver, carcinoma is the thing of evil poison, so the method for employing " treating the poisonous disease with poisonous drugs " is arranged, in the prescription of controlling the cancer medicine, the speckle insect destructive of the roots of seedlings, Scolopendra, Bufo siccus that useful toxicity is bigger, this medicine can play certain lethal effect to cancerous cell, but simultaneously human normal tissue cell is is also killed and wounded, take for a long time, be unfavorable for physical and mental health, and have the low deficiency of curative effect.

The present invention seeks to provides a kind of heat-clearing and toxic substances removing at above-mentioned deficiency, the liver eliminating stagnation that disappears, curative effect height, the treatment hepatocarcinoma new drug building lotus capsule of the pure Chinese medicinal preparation that employing avirulence Chinese medicine is formed.

The object of the present invention is achieved like this: hepatocarcinoma mostly is the disease of simulataneous insufficiency and excessive, and void is more common in the positive QI-insufficiency of whole body, sees with deficiency of both QI and YIN more; Be more common in the part in fact, with stagnation of QI-blood, excessive noxious heat is main, positive exogenous pathogen is contained, and depression and stagnation of QI is a basic pathogenesis, and satisfying with " setting upright tonification; blood circulation promoting and blood stasis dispelling, broken disease eliminating stagnation, regulating QI to relieve pain " is aim, determine that the principles of formulating prescriptions are " heat-clearing and toxic substances removing, blood stasis-eliminating and stagnation-dissipating ", Fa Ming building lotus capsule is made by following proportion raw material by weight thus: Herba Hedyotidis Diffusae 70-100 part, Rhizoma Paridis 70-100 part, Herba Lobeliae Chinensis 70-100 part, Herba Solani Nigri 70-100 part, Herba Scutellariae Barbatae 70-100 part, Herba Solani Lyrati 70-100 part, Radix Semiaquilegiae 14-20 part, Fructus Polygoni Orientalis 14-20 part, Rhizoma Curcumae 14-20 part, Pulvis Cornus Bubali Concentratus 7-10 part, Olibanum (processed) 4-6 part, Myrrha (processed) 4-6 part, Hirudo 14-20 part, Eupolyphaga Seu Steleophaga 7-10 part, Radix Ginseng 14-20 part, Radix Polygoni Multiflori Preparata 14-20 part, Carapax Trionycis (processed) 14-20 part, Fructus Mume (meat) 7-10 part, Endothelium Corneum Gigeriae Galli 7-10 part, Fructus Amomi 8-12 part.

This prescription is a monarch drug with Herba Hedyotidis Diffusae, Radix Semiaquilegiae, Rhizoma Paridis, Herba Lobeliae Chinensis, Herba Scutellariae Barbatae, Herba Solani Nigri, Herba Solani Lyrati, has heat-clearing and toxic substances removing, dispersing swelling and dissipating binds, to reach the toxic swelling caking of removing due to the showing tremendous enthusiasm poison of body endogenous dampness.But the heat-clearing and toxic substances removing medicine not only early prevention and treatment in elder generation, and to mid-term the patient usefulness of Qinghua fire-toxin is arranged, to reach the control carcinoma, prevent that other complication from taking place; With Fructus Polygoni Orientalis, Rhizoma Curcumae, Cornu Bubali, Olibanum, Myrrha, Hirudo, Eupolyphaga Seu Steleophaga is ministerial drug, has logical lively atmosphere blood, row wet dissipation heat, reducing swelling and alleviating pain is searched and is picked old amassing, and changes the eliminating mass abdominal mass and gathers, seven medicines must be joined, and specially change the dead blood of pertinacious phlegm, dredging the meridian, hard masses softening and resolving: with Radix Ginseng, Radix Polygoni Multiflori, Carapax Trionycis, Fructus Mume, Endothelium Corneum Gigeriae Galli, Fructus Amomi is adjuvant, but invigorating primordial QI, beneficial the five internal organs, the yin nourishing of enriching blood, the appetizing of being amusing, six medicine compatibilities, qi and blood tonifying, strengthening the body resistance, the evil poison diffusion of retardance.This medicine monarch, prescription is careful, plays the eliminate indigestion that uncharms altogether, the effect of liver-protecting and cancer-resisting.

This medicament preparation is as follows: Olibanum, Myrrha, Radix Polygoni Multiflori, Carapax Trionycis adopt concocted specification to carry out; Adopt water to extract its active ingredient to Herba Hedyotidis Diffusae, Rhizoma Paridis, Herba Lobeliae Chinensis, Herba Solani Nigri, Herba Scutellariae Barbatae, Herba Solani Lyrati, Radix Semiaquilegiae, specific practice is to get each herbal medicine of afore mentioned rules umber, put in the extraction vessel respectively, adding water temperature soaked 2-3 hour, each extracts three times, merge three times extracting solution, be condensed into extractum; Other each herbal medicines to not adopting water to carry in the prescription are ground into fine powder, puddle into chunky shape with extractum then, carry out drying, porphyrize, sieve, be mixed, check encapsulated or make electuary.

This medicine function: heat-clearing and toxic substances removing, blood stasis-eliminating and stagnation-dissipating.

This medicine cures mainly: hepatocarcinoma I, II phase, traditional Chinese medical science typing: damp-heat type, blood stasis type.Also effective in cure to gastric cancer, breast carcinoma simultaneously.

Usage and consumption: every day 3 times, each 6 (every of 0.25g/), and 28 days is a course of treatment, can obviously take effect a general course of treatment.

This medicine advantage is: 1, have no side effect.Show to the white mice acute toxinology experiment with to the rat long term toxicity test that through the Tianjin Institute of Medicine Science large and small white mouse does not all have poisoning and other abnormal phenomena, so clinical use should be safer.2, killing hepatoma cytosis is preferably arranged, cancer suppressing ratio can reach 94.6%.Through Academy of Military Medicine, PLA's effect experiment, by showing to the observation of curative effect of BALB/C nude mice transplantability people hepatocarcinoma and to the experimental result of the human liver cancer cell of In vitro culture, cancer suppressing ratio reaches 94.6%, observe liver cancer tissue, its major injury, the cell enlargement active degree lowers, and can see extensively, the downright bad hemorrhage district of lamellar, does not see that cancerous cell organizes interior infiltrative growth towards periphery.Cell in vitro experiment is shown this medicine has and kills and wounds the cancerous cell effect preferably, with the curative effect basically identical to the nude mice transplanted hepatoma.3, this medicine can significantly suppress hepatocarcinoma, breast carcinoma and vitro growth of gastric cancer cell.Experiment shows that this medicine can suppress the growth and the proliferation function of hepatocarcinoma, gastric cancer, breast cancer cell to the In vitro culture cancerous cell through Royal Bank Venture Capital Co., Ltd.

Embodiment:

Component	Content (kg)
			Embodiment 1	Embodiment 2
	Herba Hedyotidis Diffusae	100			70
Rhizoma Paridis			100	70
	Herba Lobeliae Chinensis	100			70
Herba Solani Nigri			100	70
	Herba Scutellariae Barbatae	100			70
Herba Solani Lyrati			100	70
	Radix Semiaquilegiae	20			16
Fructus Polygoni Orientalis			20	16
	Rhizoma Curcumae	20			16
Pulvis Cornus Bubali Concentratus			10	8
	Olibanum (system)	6			5
Myrrha (processed)			6	5
	Hirudo	20			16
Eupolyphaga Seu Steleophaga			10	8
	Radix Ginseng	20			16
Radix Polygoni Multiflori (system)			20	16
	Carapax Trionycis (system)	20			16
Fructus Mume (meat)			10	8
	Endothelium Corneum Gigeriae Galli	10			8
Fructus Amomi			12	10

Claims (1)

1, a kind of hepatocarcinoma that cures mainly is simultaneously to breast carcinoma, gastric cancer also has the building lotus capsule of therapeutic effect, it is characterized in that it is made by following proportion raw material by weight: Herba Hedyotidis Diffusae 70-100 part, Rhizoma Paridis 70-100 part, Herba Lobeliae Chinensis 70-100 part, Herba Solani Nigri 70-100 part, Herba Scutellariae Barbatae 70-100 part, Herba Solani Lyrati 70-100 part, Radix Semiaquilegiae 14-20 part, Fructus Polygoni Orientalis 14-20 part, Rhizoma Curcumae 14-20 part, Pulvis Cornus Bubali Concentratus 7-10 part, Olibanum (processed) 4-6 part, Myrrha (processed) 4-6 part, Hirudo 14-20 part, Eupolyphaga Seu Steleophaga 7-10 part, Radix Ginseng 14-20 part, Radix Polygoni Multiflori Preparata 14-20 part, Carapax Trionycis (processed) 14-20 part, Fructus Mume 7-10 part, Endothelium Corneum Gigeriae Galli 7-10 part, Fructus Amomi 8-12 part.