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CL2019000640A1 - Anticuerpos contra el virus del dengue, polipeptidos que contienen regiones fc variantes, y métodos de uso. - Google Patents

Anticuerpos contra el virus del dengue, polipeptidos que contienen regiones fc variantes, y métodos de uso.

Info

Publication number
CL2019000640A1
CL2019000640A1 CL2019000640A CL2019000640A CL2019000640A1 CL 2019000640 A1 CL2019000640 A1 CL 2019000640A1 CL 2019000640 A CL2019000640 A CL 2019000640A CL 2019000640 A CL2019000640 A CL 2019000640A CL 2019000640 A1 CL2019000640 A1 CL 2019000640A1
Authority
CL
Chile
Prior art keywords
methods
regions
polypeptides containing
dengue virus
nucleic acids
Prior art date
Application number
CL2019000640A
Other languages
English (en)
Spanish (es)
Inventor
Zenjiro Sampei
Xing'er Christine Koo
Katja Fink
Roland Zuest
Original Assignee
Chugai Pharmaceutical Co Ltd
Agency Science Tech & Res
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chugai Pharmaceutical Co Ltd, Agency Science Tech & Res filed Critical Chugai Pharmaceutical Co Ltd
Publication of CL2019000640A1 publication Critical patent/CL2019000640A1/es

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/08Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
    • C07K16/10Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from RNA viruses
    • C07K16/1081Togaviridae, e.g. flavivirus, rubella virus, hog cholera virus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/52Constant or Fc region; Isotype
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/567Framework region [FR]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
    • C07K2317/734Complement-dependent cytotoxicity [CDC]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/90Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/90Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/94Stability, e.g. half-life, pH, temperature or enzyme-resistance
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Virology (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Communicable Diseases (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
CL2019000640A 2016-09-16 2019-03-13 Anticuerpos contra el virus del dengue, polipeptidos que contienen regiones fc variantes, y métodos de uso. CL2019000640A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SG10201607778XA SG10201607778XA (en) 2016-09-16 2016-09-16 Anti-Dengue Virus Antibodies, Polypeptides Containing Variant Fc Regions, And Methods Of Use

Publications (1)

Publication Number Publication Date
CL2019000640A1 true CL2019000640A1 (es) 2019-07-12

Family

ID=61618863

Family Applications (3)

Application Number Title Priority Date Filing Date
CL2019000640A CL2019000640A1 (es) 2016-09-16 2019-03-13 Anticuerpos contra el virus del dengue, polipeptidos que contienen regiones fc variantes, y métodos de uso.
CL2024001716A CL2024001716A1 (es) 2016-09-16 2024-06-10 Anticuerpo aislado que se une a la proteína e del virus del dengue.
CL2024001715A CL2024001715A1 (es) 2016-09-16 2024-06-10 Anticuerpo aislado que se une a la proteína e del virus del dengue; y uso.

Family Applications After (2)

Application Number Title Priority Date Filing Date
CL2024001716A CL2024001716A1 (es) 2016-09-16 2024-06-10 Anticuerpo aislado que se une a la proteína e del virus del dengue.
CL2024001715A CL2024001715A1 (es) 2016-09-16 2024-06-10 Anticuerpo aislado que se une a la proteína e del virus del dengue; y uso.

Country Status (21)

Country Link
US (4) US10604561B2 (zh)
EP (1) EP3512879A4 (zh)
JP (3) JP6913161B2 (zh)
KR (2) KR102301948B1 (zh)
CN (2) CN116375853A (zh)
AR (1) AR109536A1 (zh)
AU (2) AU2017326922B2 (zh)
BR (1) BR112019004770A2 (zh)
CA (1) CA3036505A1 (zh)
CL (3) CL2019000640A1 (zh)
CO (1) CO2019002482A2 (zh)
EC (1) ECSP19018654A (zh)
IL (2) IL265290B2 (zh)
MX (2) MX2019003057A (zh)
MY (1) MY194289A (zh)
PE (1) PE20190733A1 (zh)
PH (1) PH12019500485A1 (zh)
RU (1) RU2758596C2 (zh)
SG (3) SG10201607778XA (zh)
TW (3) TW202124431A (zh)
WO (1) WO2018052375A1 (zh)

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KR20240090831A (ko) 2015-02-05 2024-06-21 추가이 세이야쿠 가부시키가이샤 이온 농도 의존적 항원 결합 도메인을 포함하는 항체, Fc 영역 개변체, IL-8에 결합하는 항체, 및 그들의 사용
SG11201801024XA (en) 2016-08-05 2018-05-30 Chugai Pharmaceutical Co Ltd Therapeutic or preventive compositions for il-8-related diseases
SG10201607778XA (en) 2016-09-16 2018-04-27 Chugai Pharmaceutical Co Ltd Anti-Dengue Virus Antibodies, Polypeptides Containing Variant Fc Regions, And Methods Of Use
CN116327926A (zh) 2018-03-15 2023-06-27 中外制药株式会社 对寨卡病毒具有交叉反应性的抗登革热病毒抗体及使用方法
WO2020051334A1 (en) 2018-09-05 2020-03-12 Takeda Vaccines, Inc. Dengue vaccine unit dose and administration thereof
US11464815B2 (en) 2018-09-05 2022-10-11 Takeda Vaccines, Inc. Dengue vaccine unit dose and administration thereof
CN116096415A (zh) * 2020-08-14 2023-05-09 中外制药株式会社 单臂的抗原结合分子及其用途
JPWO2023013618A1 (zh) * 2021-08-02 2023-02-09
CN114410588B (zh) * 2022-01-29 2022-11-04 西安电子科技大学 一种α1β1整合素依赖增强型CAR巨噬细胞及其制备方法和应用

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SG10201607778XA (en) 2016-09-16 2018-04-27 Chugai Pharmaceutical Co Ltd Anti-Dengue Virus Antibodies, Polypeptides Containing Variant Fc Regions, And Methods Of Use

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