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CL2004000412A1 - USE OF AN EP2 RECEIVER SELECTIVE ANTAGONIST COMPOUND TO TREAT PULMONARY HYPERTENSION. - Google Patents

USE OF AN EP2 RECEIVER SELECTIVE ANTAGONIST COMPOUND TO TREAT PULMONARY HYPERTENSION.

Info

Publication number
CL2004000412A1
CL2004000412A1 CL200400412A CL2004000412A CL2004000412A1 CL 2004000412 A1 CL2004000412 A1 CL 2004000412A1 CL 200400412 A CL200400412 A CL 200400412A CL 2004000412 A CL2004000412 A CL 2004000412A CL 2004000412 A1 CL2004000412 A1 CL 2004000412A1
Authority
CL
Chile
Prior art keywords
treat
facilitate
pulmonary hypertension
hypertension
treat pulmonary
Prior art date
Application number
CL200400412A
Other languages
Spanish (es)
Inventor
Angelo Constan David Alexander
Original Assignee
Pfizer Products Inc Sa Organiz
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Products Inc Sa Organiz filed Critical Pfizer Products Inc Sa Organiz
Publication of CL2004000412A1 publication Critical patent/CL2004000412A1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/433—Thidiazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/06—Antiglaucoma agents or miotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Rheumatology (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Dermatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
  • Pyridine Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

USO DE UN AGONISTA SELECTIVO DEL RECEPTOR EP2 PARA TRATAR LA HIPERTENSION PULMONAR, FACILITAR LA FUSION DE ARTICULACIONES, FACILITAR LA REPARACION DE TENDONES Y LIGAMENTOS, REDUCIR LA APARICION DE FRACTURAS SECUNDARIAS, TRATAR LA NECROSIS VASCULAR, FACILITAR LA REPERACION DEL CARTILAGO, FACILITAR LA CURACION DEL HUESO DESPUES DEL TRANSPLANTE DE UN MIEMBRO, FACILITAR LA REGENERACION HEPATICA, FACILITAR LA CURACION DE HERIDAS, REDUCIR LA APARICION DE ULCERAS GASTRICA, TRTAR LA HIPERTENSION, FACILITAR EL CRECIMIENTO DEL ESMALTE DE LOS DIENTES O LAS UNAS DE LOS DEDOS DE LAS MANOS O DE LOS PIES, TRATAR UN GLAUCOMA, TRTAR LA HIPERTENSION OCULAR Y RECUPERAR LAS LESIONES PRODUCIDAS POR UNA ENFERMEDAD METASTASICA DE HUESO.USE OF AN EP2 RECEPTOR SELECTIVE AGONIST TO TREAT PULMONARY HYPERTENSION, FACILITATE FUSION OF ARTICULATIONS, FACILITATE THE REPAIR OF TENDONS AND LIGAMENTS, REDUCE THE APPEARANCE OF SECONDARY FRACTURES, TREAT THE NECROSIS, FACILATION OF FACILITY, PACILULATION OF FACILATION BONE AFTER THE TRANSPLANT OF A MEMBER, FACILITATE THE HEPATIC REGENERATION, FACILITATE THE HEALING OF WOUNDS, REDUCE THE APPEARANCE OF GASTRIC ULCERAS, TREAT HYPERTENSION, FACILITATE THE GROWTH OF THE ENAMEL OF THE TEETH OR ONE OR THE ONE FEET, TREAT A GLAUCOMA, TREAT THE EYE HYPERTENSION AND RECOVER THE INJURIES CAUSED BY A METASTASIC BONE DISEASE.

CL200400412A 2003-03-04 2004-03-02 USE OF AN EP2 RECEIVER SELECTIVE ANTAGONIST COMPOUND TO TREAT PULMONARY HYPERTENSION. CL2004000412A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US45188903P 2003-03-04 2003-03-04

Publications (1)

Publication Number Publication Date
CL2004000412A1 true CL2004000412A1 (en) 2005-02-04

Family

ID=32962656

Family Applications (1)

Application Number Title Priority Date Filing Date
CL200400412A CL2004000412A1 (en) 2003-03-04 2004-03-02 USE OF AN EP2 RECEIVER SELECTIVE ANTAGONIST COMPOUND TO TREAT PULMONARY HYPERTENSION.

Country Status (14)

Country Link
EP (1) EP1601351A1 (en)
JP (1) JP2006519250A (en)
KR (1) KR20050105511A (en)
CN (1) CN1859903A (en)
AU (1) AU2004216898A1 (en)
BR (1) BRPI0408061A (en)
CA (1) CA2518193A1 (en)
CL (1) CL2004000412A1 (en)
MX (1) MXPA05009398A (en)
NZ (1) NZ541828A (en)
PL (1) PL378748A1 (en)
TW (1) TW200424176A (en)
WO (1) WO2004078169A1 (en)
ZA (1) ZA200506532B (en)

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GB0302094D0 (en) 2003-01-29 2003-02-26 Pharmagene Lab Ltd EP4 receptor antagonists
WO2005009468A1 (en) * 2003-07-25 2005-02-03 Ono Pharmaceutical Co., Ltd. Remedy for cartilage-related diseases
GB0324269D0 (en) 2003-10-16 2003-11-19 Pharmagene Lab Ltd EP4 receptor antagonists
US8604055B2 (en) 2004-12-31 2013-12-10 Dr. Reddy's Laboratories Ltd. Substituted benzylamino quinolines as cholesterol ester-transfer protein inhibitors
EP1848430B1 (en) 2004-12-31 2017-08-02 Dr. Reddy's Laboratories Ltd. Novel benzylamine derivatives as cetp inhibitors
US7915316B2 (en) 2005-08-22 2011-03-29 Allergan, Inc Sulfonamides
US7696235B2 (en) * 2005-08-29 2010-04-13 Allergan, Inc. EP2 receptor agonists for treating glaucoma
MX373998B (en) 2006-03-24 2020-07-22 Childrens Medical Center USE OF A HEMATOPOIETIC STEM CELL (HSC) MODULATOR TO PROMOTE HSC GROWTH.
BRPI0714683A2 (en) 2006-07-28 2013-03-26 Pfizer Prod Inc ep2 agonists
US9402852B2 (en) * 2006-10-20 2016-08-02 Children's Medical Center Corporation Method to enhance tissue regeneration
RO128637A2 (en) * 2007-08-21 2013-07-30 Senomyx, Inc. Identification of human t2r receptors responding to bitter compounds extracting the bitter taste from compositions and the use thereof in analyses for identifying the compounds inhibiting the bitter taste in compositions and the use thereof
PL2264009T3 (en) * 2008-03-12 2019-07-31 Ube Industries, Ltd. Pyridylaminoacetic acid compound
WO2010096264A2 (en) 2009-02-03 2010-08-26 Children's Medical Center Corporation Methods for enhancing hematopoietic stem/progenitor cell engraftment
US9051548B2 (en) 2009-02-03 2015-06-09 Children's Medical Center Corporation Methods for enhancing hematopoietic stem/progenitor cell engraftment
WO2010113957A1 (en) * 2009-03-30 2010-10-07 宇部興産株式会社 Pharmaceutical composition for treating or preventing glaucoma
WO2010116270A1 (en) 2009-04-10 2010-10-14 Pfizer Inc. Ep2/4 agonists
WO2011030872A1 (en) * 2009-09-11 2011-03-17 宇部興産株式会社 Sulfonamide compounds
WO2011030871A1 (en) * 2009-09-11 2011-03-17 宇部興産株式会社 N-substituted heteroaryl compounds
KR20120068902A (en) * 2009-09-11 2012-06-27 우베 고산 가부시키가이샤 Aniline compounds
WO2011030865A1 (en) * 2009-09-11 2011-03-17 宇部興産株式会社 Substituted zenzyl compounds
JP2011057633A (en) * 2009-09-11 2011-03-24 Ube Industries Ltd Medicine containing pyridylaminoacetic acid compound
WO2011030873A1 (en) * 2009-09-11 2011-03-17 宇部興産株式会社 Benzyl compounds
US20120226036A1 (en) * 2009-09-11 2012-09-06 Ube Industries, Ltd. Substituted carbonyl compound
CN102666490A (en) * 2009-12-25 2012-09-12 宇部兴产株式会社 Aminopyridine compound
EP2744803A2 (en) 2011-08-18 2014-06-25 Dr. Reddy's Laboratories Ltd. Substituted heterocyclic amine compounds as cholestryl ester-transfer protein (cetp) inhibitors
JP6140168B2 (en) 2011-09-27 2017-05-31 ドクター レディズ ラボラトリーズ リミテッド 5-Benzylaminomethyl-6-aminopyrazolo [3,4-B] pyridine derivatives as cholesteryl ester transfer protein (CETP) inhibitors useful for the treatment of atherosclerosis
EP2785350B1 (en) 2011-12-02 2018-05-02 Fate Therapeutics, Inc. Improved methods of treating ischemia
WO2013082243A1 (en) 2011-12-02 2013-06-06 Fate Therapeutics, Inc. Enhanced stem cell composition
US9447078B2 (en) * 2012-01-20 2016-09-20 Acucela Inc. Substituted heterocyclic compounds for disease treatment
WO2014078434A1 (en) * 2012-11-16 2014-05-22 Allergan, Inc. Compounds and methods for skin repair
WO2014150602A1 (en) 2013-03-15 2014-09-25 Fate Therapeutics, Inc. Cell potency assay for therapeutic potential
SG11201507976YA (en) 2013-03-28 2015-10-29 Ube Industries Substituted biaryl compound
EA031609B1 (en) 2014-05-13 2019-01-31 Новартис Аг Compounds and compositions for inducing chondrogenesis
CN106397149B (en) * 2016-08-26 2019-05-21 大连奇凯医药科技有限公司 The preparation method of pentafluorobenzaldehyde
CN115636761B (en) * 2021-07-20 2024-07-05 中国石油天然气股份有限公司 Oil-soluble surfactant, oil displacement agent and application thereof

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CA2113787A1 (en) * 1993-01-29 1994-07-30 Nobuyuki Hamanaka Carbocyclic sulfonamides
WO1998027976A1 (en) * 1996-12-20 1998-07-02 Pfizer Inc. Prevention and treatment of skeletal disorder with ep2 receptor subtype selective prostaglandin e2 agonists
UA67754C2 (en) * 1997-10-10 2004-07-15 Пфайзер, Інк. Prostaglandin agonists and use thereof for the treatment of bone disorders
US6376533B1 (en) * 2000-10-20 2002-04-23 Allergan Sales, Inc. Omega-cycloalkyl 17-heteroaryl prostaglandin E2 analogs as EP2-receptor agonists

Also Published As

Publication number Publication date
CN1859903A (en) 2006-11-08
TW200424176A (en) 2004-11-16
AU2004216898A1 (en) 2004-09-16
NZ541828A (en) 2008-06-30
JP2006519250A (en) 2006-08-24
WO2004078169A8 (en) 2005-04-21
EP1601351A1 (en) 2005-12-07
KR20050105511A (en) 2005-11-04
WO2004078169A1 (en) 2004-09-16
ZA200506532B (en) 2007-03-28
BRPI0408061A (en) 2006-02-14
PL378748A1 (en) 2006-05-15
MXPA05009398A (en) 2005-12-05
CA2518193A1 (en) 2004-09-16

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