CA3136061A1 - Method for producing knock-in cell - Google Patents
Method for producing knock-in cell Download PDFInfo
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- CA3136061A1 CA3136061A1 CA3136061A CA3136061A CA3136061A1 CA 3136061 A1 CA3136061 A1 CA 3136061A1 CA 3136061 A CA3136061 A CA 3136061A CA 3136061 A CA3136061 A CA 3136061A CA 3136061 A1 CA3136061 A1 CA 3136061A1
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CN112746074B (zh) * | 2020-12-16 | 2022-12-02 | 南方医科大学皮肤病医院(广东省皮肤病医院、广东省皮肤性病防治中心、中国麻风防治研究中心) | Keratin 5-IRES-eGFP敲入的hESCs细胞系的构建及诱导分化方法 |
WO2024102954A1 (en) | 2022-11-10 | 2024-05-16 | Massachusetts Institute Of Technology | Activation induced clipping system (aics) |
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EP1476547B1 (en) | 2002-01-23 | 2006-12-06 | The University of Utah Research Foundation | Targeted chromosomal mutagenesis using zinc finger nucleases |
US20110239315A1 (en) | 2009-01-12 | 2011-09-29 | Ulla Bonas | Modular dna-binding domains and methods of use |
NO2510096T3 (pt) | 2009-12-10 | 2015-03-21 | ||
GB201122458D0 (en) | 2011-12-30 | 2012-02-08 | Univ Wageningen | Modified cascade ribonucleoproteins and uses thereof |
US9637739B2 (en) | 2012-03-20 | 2017-05-02 | Vilnius University | RNA-directed DNA cleavage by the Cas9-crRNA complex |
UA118014C2 (uk) | 2012-05-25 | 2018-11-12 | Те Ріджентс Оф Те Юніверсіті Оф Каліфорнія | Спосіб модифікації днк-мішені |
PL2921557T3 (pl) | 2012-12-12 | 2017-03-31 | Broad Inst Inc | Projektowanie systemów, sposoby i optymalizowane kompozycje kierujące do manipulacji sekwencją |
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JP5931022B2 (ja) | 2013-08-09 | 2016-06-08 | 国立大学法人広島大学 | Dna結合ドメインを含むポリペプチド |
US10787684B2 (en) | 2013-11-19 | 2020-09-29 | President And Fellows Of Harvard College | Large gene excision and insertion |
US10362771B2 (en) * | 2014-11-20 | 2019-07-30 | Kyoto University | Method for knock-in of DNA into target region of mammalian genome, and cell |
US9790490B2 (en) | 2015-06-18 | 2017-10-17 | The Broad Institute Inc. | CRISPR enzymes and systems |
US11905521B2 (en) * | 2015-11-17 | 2024-02-20 | The Chinese University Of Hong Kong | Methods and systems for targeted gene manipulation |
EP3546575B1 (en) | 2016-11-28 | 2024-07-17 | Osaka University | Genome editing method |
US11371030B2 (en) | 2017-05-31 | 2022-06-28 | The University Of Tokyo | Modified Cas9 protein and use thereof |
WO2018225858A1 (ja) | 2017-06-08 | 2018-12-13 | 国立大学法人大阪大学 | Dnaが編集された真核細胞を製造する方法、および当該方法に用いられるキット |
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