CA3178446A1 - Procedes de regulation a base fluidique, d'elimination de bouchon et de multiplexage et dispositifs de traitement de particules en suspension dans un liquide - Google Patents
Procedes de regulation a base fluidique, d'elimination de bouchon et de multiplexage et dispositifs de traitement de particules en suspension dans un liquideInfo
- Publication number
- CA3178446A1 CA3178446A1 CA3178446A CA3178446A CA3178446A1 CA 3178446 A1 CA3178446 A1 CA 3178446A1 CA 3178446 A CA3178446 A CA 3178446A CA 3178446 A CA3178446 A CA 3178446A CA 3178446 A1 CA3178446 A1 CA 3178446A1
- Authority
- CA
- Canada
- Prior art keywords
- sensor
- tube end
- valve
- plug removal
- removal device
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000002245 particle Substances 0.000 title claims abstract description 401
- 239000007788 liquid Substances 0.000 title claims abstract description 138
- 238000012545 processing Methods 0.000 title claims abstract description 106
- 238000000034 method Methods 0.000 title claims abstract description 78
- 238000004891 communication Methods 0.000 claims description 82
- 230000001105 regulatory effect Effects 0.000 claims description 79
- 238000001514 detection method Methods 0.000 claims description 75
- 239000012530 fluid Substances 0.000 claims description 72
- 230000004044 response Effects 0.000 claims description 38
- 230000003287 optical effect Effects 0.000 claims description 26
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 16
- 238000000926 separation method Methods 0.000 claims description 9
- 210000002257 embryonic structure Anatomy 0.000 description 11
- 230000005484 gravity Effects 0.000 description 11
- 230000008859 change Effects 0.000 description 8
- 238000011143 downstream manufacturing Methods 0.000 description 8
- 239000011521 glass Substances 0.000 description 8
- 238000010191 image analysis Methods 0.000 description 8
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- 238000004590 computer program Methods 0.000 description 6
- 230000008021 deposition Effects 0.000 description 6
- 230000007246 mechanism Effects 0.000 description 6
- 230000008901 benefit Effects 0.000 description 5
- 230000008569 process Effects 0.000 description 5
- 229920001971 elastomer Polymers 0.000 description 4
- 238000003384 imaging method Methods 0.000 description 4
- 239000000203 mixture Substances 0.000 description 4
- 230000002706 hydrostatic effect Effects 0.000 description 3
- 238000004519 manufacturing process Methods 0.000 description 3
- 238000012986 modification Methods 0.000 description 3
- 230000004048 modification Effects 0.000 description 3
- 230000002572 peristaltic effect Effects 0.000 description 3
- 238000010276 construction Methods 0.000 description 2
- 230000001276 controlling effect Effects 0.000 description 2
- 238000006073 displacement reaction Methods 0.000 description 2
- 230000006870 function Effects 0.000 description 2
- 230000007257 malfunction Effects 0.000 description 2
- 239000011159 matrix material Substances 0.000 description 2
- 238000012544 monitoring process Methods 0.000 description 2
- 238000012634 optical imaging Methods 0.000 description 2
- 230000010349 pulsation Effects 0.000 description 2
- 230000008844 regulatory mechanism Effects 0.000 description 2
- 238000012360 testing method Methods 0.000 description 2
- 230000007704 transition Effects 0.000 description 2
- 230000009471 action Effects 0.000 description 1
- 230000002411 adverse Effects 0.000 description 1
- 238000004458 analytical method Methods 0.000 description 1
- 238000004364 calculation method Methods 0.000 description 1
- 230000001419 dependent effect Effects 0.000 description 1
- 238000013461 design Methods 0.000 description 1
- 238000003708 edge detection Methods 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 238000005286 illumination Methods 0.000 description 1
- 230000003993 interaction Effects 0.000 description 1
- 210000001161 mammalian embryo Anatomy 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 238000005259 measurement Methods 0.000 description 1
- 239000004033 plastic Substances 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 229920002379 silicone rubber Polymers 0.000 description 1
- 239000004945 silicone rubber Substances 0.000 description 1
- 230000000392 somatic effect Effects 0.000 description 1
- 238000010561 standard procedure Methods 0.000 description 1
- 230000001954 sterilising effect Effects 0.000 description 1
- 238000004659 sterilization and disinfection Methods 0.000 description 1
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Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N15/14—Optical investigation techniques, e.g. flow cytometry
- G01N15/1429—Signal processing
- G01N15/1433—Signal processing using image recognition
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N15/14—Optical investigation techniques, e.g. flow cytometry
- G01N15/1404—Handling flow, e.g. hydrodynamic focusing
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/06—Investigating concentration of particle suspensions
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/06—Investigating concentration of particle suspensions
- G01N15/075—Investigating concentration of particle suspensions by optical means
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/06—Investigating concentration of particle suspensions
- G01N2015/0687—Investigating concentration of particle suspensions in solutions, e.g. non volatile residue
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N2015/1027—Determining speed or velocity of a particle
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N15/14—Optical investigation techniques, e.g. flow cytometry
- G01N15/1404—Handling flow, e.g. hydrodynamic focusing
- G01N2015/1418—Eliminating clogging of debris
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N15/14—Optical investigation techniques, e.g. flow cytometry
- G01N2015/1486—Counting the particles
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- Dispersion Chemistry (AREA)
- Physics & Mathematics (AREA)
- Health & Medical Sciences (AREA)
- Pathology (AREA)
- Analytical Chemistry (AREA)
- Immunology (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Engineering & Computer Science (AREA)
- Signal Processing (AREA)
- Physical Or Chemical Processes And Apparatus (AREA)
- Computer Vision & Pattern Recognition (AREA)
Abstract
L'invention concerne des procédés et des dispositifs pour la régulation automatisée à base fluidique de particules en suspension liquide et l'élimination de bouchon (de particules) à partir de points d'arrêt possibles dans le canal d'écoulement de liquide et des procédés pour le traitement de particules parallèles multiples. L'appareil comprend des canaux d'écoulement, des moyens de direction d'écoulement, des détecteurs de particules et une unité de commande.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202063003983P | 2020-04-02 | 2020-04-02 | |
| US63/003,983 | 2020-04-02 | ||
| PCT/US2021/025085 WO2021202662A1 (fr) | 2020-04-02 | 2021-03-31 | Procédés de régulation à base fluidique, d'élimination de bouchon et de multiplexage et dispositifs de traitement de particules en suspension dans un liquide |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA3178446A1 true CA3178446A1 (fr) | 2021-10-07 |
Family
ID=77929426
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA3178446A Pending CA3178446A1 (fr) | 2020-04-02 | 2021-03-31 | Procedes de regulation a base fluidique, d'elimination de bouchon et de multiplexage et dispositifs de traitement de particules en suspension dans un liquide |
Country Status (4)
| Country | Link |
|---|---|
| US (1) | US20230168169A1 (fr) |
| EP (1) | EP4127854A4 (fr) |
| CA (1) | CA3178446A1 (fr) |
| WO (1) | WO2021202662A1 (fr) |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3719090A (en) * | 1971-03-08 | 1973-03-06 | Autometrics Co | Method and apparatus for measurement of particle size and percent solids in multiple process flowstreams |
| DE2929430C2 (de) * | 1979-07-20 | 1981-10-01 | Stahlwerke Peine-Salzgitter Ag, 3150 Peine | Verfahren und Einrichtung zur Analyse des Feststoffanteils in einem hydraulischen Förderstrom aus Feststoffteilchen und einer Trägerflüssigkeit |
| US6211956B1 (en) * | 1998-10-15 | 2001-04-03 | Particle Sizing Systems, Inc. | Automatic dilution system for high-resolution particle size analysis |
| US6751525B1 (en) * | 2000-06-08 | 2004-06-15 | Beverage Works, Inc. | Beverage distribution and dispensing system and method |
| US8452460B2 (en) * | 2008-04-10 | 2013-05-28 | Georgia Tech Research Corporation | Fluidics-based orientation and sorting device for plant embryos |
| CA2775907C (fr) * | 2009-10-09 | 2020-02-25 | Georgia Tech Research Corporation | Dispositif de separation, dispositif de depot et systeme de manipulation d'embryons somatiques vegetaux |
| US10343165B2 (en) * | 2013-09-05 | 2019-07-09 | Bio-Rad Laboratories, Inc. | On-demand particle dispensing system |
| US10883081B2 (en) * | 2016-12-20 | 2021-01-05 | J. D. Irving, Limited | Systems, methods and apparatuses for processing plant embryos |
-
2021
- 2021-03-31 CA CA3178446A patent/CA3178446A1/fr active Pending
- 2021-03-31 US US17/916,666 patent/US20230168169A1/en active Pending
- 2021-03-31 EP EP21782291.5A patent/EP4127854A4/fr active Pending
- 2021-03-31 WO PCT/US2021/025085 patent/WO2021202662A1/fr unknown
Also Published As
| Publication number | Publication date |
|---|---|
| WO2021202662A1 (fr) | 2021-10-07 |
| EP4127854A4 (fr) | 2024-04-10 |
| US20230168169A1 (en) | 2023-06-01 |
| EP4127854A1 (fr) | 2023-02-08 |
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