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CA1056372A - Method of preparation of 3-methylenecephams - Google Patents

Method of preparation of 3-methylenecephams

Info

Publication number
CA1056372A
CA1056372A CA240,644A CA240644A CA1056372A CA 1056372 A CA1056372 A CA 1056372A CA 240644 A CA240644 A CA 240644A CA 1056372 A CA1056372 A CA 1056372A
Authority
CA
Canada
Prior art keywords
methyl
methylenecepham
oxide
carboxylate
oxo
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA240,644A
Other languages
English (en)
French (fr)
Inventor
Stjepan Kukolja
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Eli Lilly and Co
Original Assignee
Eli Lilly and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eli Lilly and Co filed Critical Eli Lilly and Co
Priority to CA320,196A priority Critical patent/CA1080221A/en
Application granted granted Critical
Publication of CA1056372A publication Critical patent/CA1056372A/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D205/00Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D205/02Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D205/06Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D205/08Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
    • C07D205/09Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams with a sulfur atom directly attached in position 4
    • C07D205/095Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams with a sulfur atom directly attached in position 4 and with a nitrogen atom directly attached in position 3

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
CA240,644A 1974-12-24 1975-11-27 Method of preparation of 3-methylenecephams Expired CA1056372A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CA320,196A CA1080221A (en) 1974-12-24 1979-01-24 Method of preparation of 3-methylenecephams

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US53628074A 1974-12-24 1974-12-24
US63273375A 1975-11-19 1975-11-19

Publications (1)

Publication Number Publication Date
CA1056372A true CA1056372A (en) 1979-06-12

Family

ID=27065082

Family Applications (1)

Application Number Title Priority Date Filing Date
CA240,644A Expired CA1056372A (en) 1974-12-24 1975-11-27 Method of preparation of 3-methylenecephams

Country Status (25)

Country Link
JP (1) JPS606960B2 (pl)
AR (1) AR220505A1 (pl)
AT (1) AT341672B (pl)
AU (1) AU503202B2 (pl)
BE (1) BE837041A (pl)
BG (2) BG27236A3 (pl)
CA (1) CA1056372A (pl)
CH (3) CH625528A5 (pl)
CS (1) CS191291B2 (pl)
DD (2) DD124985A5 (pl)
DE (1) DE2556045A1 (pl)
DK (1) DK157137C (pl)
ES (2) ES443829A1 (pl)
FR (2) FR2333804A1 (pl)
GB (1) GB1536288A (pl)
GR (1) GR59922B (pl)
HU (2) HU175226B (pl)
IE (1) IE42190B1 (pl)
IL (1) IL48565A (pl)
NL (1) NL182880C (pl)
PL (2) PL113883B1 (pl)
RO (2) RO74273A (pl)
SE (2) SE431547B (pl)
SU (1) SU799667A3 (pl)
YU (2) YU324875A (pl)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4289695A (en) * 1978-11-13 1981-09-15 Eli Lilly And Company Process for preparing 2-chlorosulfinylazetidinones
US4190724A (en) * 1978-11-13 1980-02-26 Eli Lilly And Company Process for 3-exomethylenecepham sulfoxides
GB2099817B (en) * 1981-04-10 1985-05-15 Otsuka Kagaku Yakuhin Azetidinone derivatives and process for the preparation of the same
US4436596A (en) * 1982-11-16 1984-03-13 Eli Lilly And Company N-Substituted-2-(R)-(sulfinic acid)-3-(S)-(acylamido)-4-oxo-azetidines and process
DE4230053A1 (de) * 1992-09-08 1994-03-10 Pliva Handels Gmbh 4-Oxo-azetidin-2-sulfonsäureamide und ihre Salze, Verfahren zu deren Herstellung und ihre Verwendung

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3843682A (en) * 1972-05-15 1974-10-22 Lilly Co Eli 2-chlorosulfinyl-3-imido-azetedin-4-ones

Also Published As

Publication number Publication date
CH626604A5 (en) 1981-11-30
RO74273A (ro) 1981-08-17
AU503202B2 (en) 1979-08-30
FR2333804A1 (fr) 1977-07-01
DE2556045A1 (de) 1976-07-08
IE42190B1 (en) 1980-06-18
BE837041A (fr) 1976-06-23
YU206481A (en) 1983-06-30
HU175226B (hu) 1980-06-28
DK157137C (da) 1990-04-16
DK585875A (da) 1976-06-25
CH628620A5 (en) 1982-03-15
SU799667A3 (ru) 1981-01-23
DE2556045C2 (pl) 1990-08-09
ES443829A1 (es) 1978-03-01
NL182880C (nl) 1988-06-01
IL48565A (en) 1979-09-30
SE7514550L (sv) 1976-06-25
BG27236A3 (en) 1979-09-14
PL114521B1 (en) 1981-02-28
AU8708475A (en) 1977-06-02
HU177431B (en) 1981-10-28
IE42190L (en) 1976-06-24
DK157137B (da) 1989-11-13
YU324875A (en) 1982-02-28
JPS5188992A (en) 1976-08-04
ATA980475A (de) 1977-06-15
BG31072A4 (en) 1981-10-15
PL113883B1 (en) 1981-01-31
RO68478A (ro) 1981-08-30
SE431547B (sv) 1984-02-13
FR2333804B1 (pl) 1979-05-18
IL48565A0 (en) 1976-01-30
SE444810B (sv) 1986-05-12
DD124985A5 (pl) 1977-03-23
AR220505A1 (es) 1980-11-14
JPS606960B2 (ja) 1985-02-21
FR2300080A1 (fr) 1976-09-03
CS191291B2 (en) 1979-06-29
FR2300080B1 (pl) 1979-06-15
ES457884A1 (es) 1978-08-16
DD130933A5 (de) 1978-05-17
NL7515069A (nl) 1976-06-28
SE7906899L (sv) 1979-08-17
GB1536288A (en) 1978-12-20
AT341672B (de) 1978-02-27
NL182880B (nl) 1988-01-04
CH625528A5 (en) 1981-09-30
GR59922B (en) 1978-03-20

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