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BRPI0919635A2 - processo para preparação de cinacalcet - Google Patents

processo para preparação de cinacalcet

Info

Publication number
BRPI0919635A2
BRPI0919635A2 BRPI0919635A BRPI0919635A BRPI0919635A2 BR PI0919635 A2 BRPI0919635 A2 BR PI0919635A2 BR PI0919635 A BRPI0919635 A BR PI0919635A BR PI0919635 A BRPI0919635 A BR PI0919635A BR PI0919635 A2 BRPI0919635 A2 BR PI0919635A2
Authority
BR
Brazil
Prior art keywords
cinacalcet
preparation
Prior art date
Application number
BRPI0919635A
Other languages
English (en)
Inventor
Giorgio Soriato
Johnny Foletto
Massimiliano Forcato
Massimo Verzini
Nicola Catozzi
Roberto Giovanetti
Original Assignee
Zach System Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zach System Spa filed Critical Zach System Spa
Publication of BRPI0919635A2 publication Critical patent/BRPI0919635A2/pt
Publication of BRPI0919635A8 publication Critical patent/BRPI0919635A8/pt
Publication of BRPI0919635B1 publication Critical patent/BRPI0919635B1/pt
Publication of BRPI0919635B8 publication Critical patent/BRPI0919635B8/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C225/00Compounds containing amino groups and doubly—bound oxygen atoms bound to the same carbon skeleton, at least one of the doubly—bound oxygen atoms not being part of a —CHO group, e.g. amino ketones
    • C07C225/02Compounds containing amino groups and doubly—bound oxygen atoms bound to the same carbon skeleton, at least one of the doubly—bound oxygen atoms not being part of a —CHO group, e.g. amino ketones having amino groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C225/14Compounds containing amino groups and doubly—bound oxygen atoms bound to the same carbon skeleton, at least one of the doubly—bound oxygen atoms not being part of a —CHO group, e.g. amino ketones having amino groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being unsaturated
    • C07C225/16Compounds containing amino groups and doubly—bound oxygen atoms bound to the same carbon skeleton, at least one of the doubly—bound oxygen atoms not being part of a —CHO group, e.g. amino ketones having amino groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being unsaturated and containing six-membered aromatic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C209/00Preparation of compounds containing amino groups bound to a carbon skeleton
    • C07C209/68Preparation of compounds containing amino groups bound to a carbon skeleton from amines, by reactions not involving amino groups, e.g. reduction of unsaturated amines, aromatisation, or substitution of the carbon skeleton
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C211/00Compounds containing amino groups bound to a carbon skeleton
    • C07C211/01Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms
    • C07C211/26Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms of an unsaturated carbon skeleton containing at least one six-membered aromatic ring
    • C07C211/30Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms of an unsaturated carbon skeleton containing at least one six-membered aromatic ring the six-membered aromatic ring being part of a condensed ring system formed by two rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C215/00Compounds containing amino and hydroxy groups bound to the same carbon skeleton
    • C07C215/02Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C215/22Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being unsaturated
    • C07C215/28Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being unsaturated and containing six-membered aromatic rings
    • C07C215/30Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being unsaturated and containing six-membered aromatic rings containing hydroxy groups and carbon atoms of six-membered aromatic rings bound to the same carbon atom of the carbon skeleton
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00Indexing scheme relating to specific properties of organic compounds
    • C07B2200/07Optical isomers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
BRPI0919635A 2008-10-28 2009-10-16 processo para preparação de cinacalcet BRPI0919635B8 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP08167762.7 2008-10-28
EP08167762 2008-10-28
PCT/EP2009/063603 WO2010049293A2 (en) 2008-10-28 2009-10-16 Process for preparing cinacalcet

Publications (4)

Publication Number Publication Date
BRPI0919635A2 true BRPI0919635A2 (pt) 2015-12-01
BRPI0919635A8 BRPI0919635A8 (pt) 2017-07-11
BRPI0919635B1 BRPI0919635B1 (pt) 2021-03-09
BRPI0919635B8 BRPI0919635B8 (pt) 2021-05-25

Family

ID=42041800

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0919635A BRPI0919635B8 (pt) 2008-10-28 2009-10-16 processo para preparação de cinacalcet

Country Status (15)

Country Link
US (1) US8614353B2 (pt)
EP (1) EP2358659B1 (pt)
JP (1) JP5514218B2 (pt)
CN (1) CN102159533B (pt)
AU (1) AU2009309860B2 (pt)
BR (1) BRPI0919635B8 (pt)
CA (1) CA2734971C (pt)
CY (1) CY1113722T1 (pt)
ES (1) ES2401851T3 (pt)
HR (1) HRP20130154T1 (pt)
IL (1) IL211307A0 (pt)
PL (1) PL2358659T3 (pt)
PT (1) PT2358659E (pt)
SI (1) SI2358659T1 (pt)
WO (1) WO2010049293A2 (pt)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2010094674A2 (en) * 2009-02-19 2010-08-26 Zach System S.P.A. Process for preparing cinacalcet hydrochloride
EP2475641B1 (en) 2009-09-10 2013-11-06 ZaCh System S.p.A. Process for preparing cinacalcet
CZ303627B6 (cs) * 2011-11-25 2013-01-16 Zentiva, K.S. Zpusob výroby Cinacalcetu
CN103664577B (zh) * 2012-09-06 2015-04-08 北京万生药业有限责任公司 一种西那卡塞中间体的制备方法
FR2995307A1 (fr) 2012-09-07 2014-03-14 Prod Chim Auxiliaires Et De Synthese Procede de preparation du cinacalcet et de ses sels pharmaceutiquement acceptables
CN106810452B (zh) * 2017-01-13 2018-12-28 华北水利水电大学 一种盐酸西那卡塞的制备方法
CN106831441B (zh) * 2017-01-23 2019-04-02 江苏康思尔医药科技有限公司 一种盐酸西那卡塞的制备方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1928817A1 (en) * 2006-04-27 2008-06-11 Teva Pharmaceutical Industries Ltd Process for the preparation of cinacalcet base
MX2008013684A (es) * 2006-04-27 2008-11-06 Teva Pharma Proceso para la preparacion de base de cinacalcet.
WO2008035381A2 (en) * 2006-09-22 2008-03-27 Ind-Swift Laboratories Limited Process for the preparation of amine derivatives as calcimimetics
WO2008117299A1 (en) * 2007-03-26 2008-10-02 Macleods Pharmaceuticals Limited Process for preparing cinacalcet hydrochloride

Also Published As

Publication number Publication date
CY1113722T1 (el) 2016-06-22
AU2009309860A1 (en) 2010-05-06
US8614353B2 (en) 2013-12-24
WO2010049293A2 (en) 2010-05-06
SI2358659T1 (sl) 2013-04-30
CA2734971A1 (en) 2010-05-06
BRPI0919635B8 (pt) 2021-05-25
IL211307A0 (en) 2011-04-28
ES2401851T3 (es) 2013-04-25
EP2358659A2 (en) 2011-08-24
EP2358659B1 (en) 2012-12-26
AU2009309860B2 (en) 2015-07-23
JP2012506847A (ja) 2012-03-22
JP5514218B2 (ja) 2014-06-04
US20110207965A1 (en) 2011-08-25
CA2734971C (en) 2017-01-31
HRP20130154T1 (hr) 2013-03-31
CN102159533A (zh) 2011-08-17
PL2358659T3 (pl) 2013-06-28
PT2358659E (pt) 2013-03-28
WO2010049293A3 (en) 2010-10-21
CN102159533B (zh) 2014-08-27
BRPI0919635A8 (pt) 2017-07-11
BRPI0919635B1 (pt) 2021-03-09

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Legal Events

Date Code Title Description
B25A Requested transfer of rights approved

Owner name: F.I.S. - FABBRICA ITALIANA SINTETICI S.P.A. (IT)

B06T Formal requirements before examination [chapter 6.20 patent gazette]
B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]

Free format text: DE ACORDO COM O ARTIGO 229-C DA LEI NO 10196/2001, QUE MODIFICOU A LEI NO 9279/96, A CONCESSAO DA PATENTE ESTA CONDICIONADA A ANUENCIA PREVIA DA ANVISA. CONSIDERANDO A APROVACAO DOS TERMOS DO PARECER NO 337/PGF/EA/2010, BEM COMO A PORTARIA INTERMINISTERIAL NO 1065 DE 24/05/2012, ENCAMINHA-SE O PRESENTE PEDIDO PARA AS PROVIDENCIAS CABIVEIS.

B07E Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 10 (DEZ) ANOS CONTADOS A PARTIR DE 09/03/2021, OBSERVADAS AS CONDICOES LEGAIS.

B16C Correction of notification of the grant [chapter 16.3 patent gazette]

Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 16/10/2009 OBSERVADAS AS CONDICOES LEGAIS. PATENTE CONCEDIDA CONFORME ADI 5.529/DF