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BRPI0914185A2 - Método para preparar sais de montelucaste de sódio - Google Patents

Método para preparar sais de montelucaste de sódio

Info

Publication number
BRPI0914185A2
BRPI0914185A2 BRPI0914185-5A BRPI0914185A BRPI0914185A2 BR PI0914185 A2 BRPI0914185 A2 BR PI0914185A2 BR PI0914185 A BRPI0914185 A BR PI0914185A BR PI0914185 A2 BRPI0914185 A2 BR PI0914185A2
Authority
BR
Brazil
Prior art keywords
preparing sodium
sodium montelukast
montelukast salts
salts
preparing
Prior art date
Application number
BRPI0914185-5A
Other languages
English (en)
Inventor
In Sang Lee
Seok Ju Lee
Jae Eun Kang
Original Assignee
Lg Life Sciences Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lg Life Sciences Ltd filed Critical Lg Life Sciences Ltd
Publication of BRPI0914185A2 publication Critical patent/BRPI0914185A2/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F1/00—Compounds containing elements of Groups 1 or 11 of the Periodic Table
    • C07F1/04—Sodium compounds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/18—Halogen atoms or nitro radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/02—Nasal agents, e.g. decongestants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Pulmonology (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Immunology (AREA)
  • Otolaryngology (AREA)
  • Quinoline Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
BRPI0914185-5A 2008-09-26 2009-09-25 Método para preparar sais de montelucaste de sódio BRPI0914185A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR20080094731 2008-09-26
PCT/KR2009/005472 WO2010036048A2 (ko) 2008-09-26 2009-09-25 몬테루카스트 나트륨염의 제조방법

Publications (1)

Publication Number Publication Date
BRPI0914185A2 true BRPI0914185A2 (pt) 2015-08-04

Family

ID=42060289

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0914185-5A BRPI0914185A2 (pt) 2008-09-26 2009-09-25 Método para preparar sais de montelucaste de sódio

Country Status (6)

Country Link
US (1) US8426600B2 (pt)
JP (1) JP5531018B2 (pt)
KR (1) KR101123292B1 (pt)
CN (1) CN102164897B (pt)
BR (1) BRPI0914185A2 (pt)
WO (1) WO2010036048A2 (pt)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100990046B1 (ko) * 2010-07-30 2010-10-26 동국제약 주식회사 신규한 몬테루카스트 4-할로 벤질아민염 및 이를 이용한 몬테루카스트 나트륨염의 제조방법
KR20130041664A (ko) * 2011-10-17 2013-04-25 주식회사 엘지생명과학 고순도 몬테루카스트 나트륨 염의 제조 방법
CN104055741B (zh) * 2013-03-18 2017-02-15 青岛大学 一种孟鲁司特钠片剂及其制备方法
CN103570618A (zh) * 2013-09-30 2014-02-12 浙江车头制药股份有限公司 一种孟鲁司特钠盐的制备方法
CN105622500B (zh) * 2016-02-29 2018-03-02 山东新时代药业有限公司 孟鲁司特钠中间体的制备方法
US10966943B2 (en) 2018-09-06 2021-04-06 Innopharmascreen Inc. Methods and compositions for treatment of asthma or parkinson's disease

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK0480717T3 (da) * 1990-10-12 1999-02-08 Merck Frosst Canada Inc Umættede hydroxyalkylquinolinsyrer som leukotrienantagonister
TW416948B (en) * 1993-12-28 2001-01-01 Merck & Co Inc Process for the preparation of leukotriene antagonists
US6716452B1 (en) * 2000-08-22 2004-04-06 New River Pharmaceuticals Inc. Active agent delivery systems and methods for protecting and administering active agents
EP1708708A1 (en) * 2004-01-30 2006-10-11 Teva Pharmaceutical Industries Ltd. Montelukast free acid polymorphs
KR100815670B1 (ko) * 2004-04-21 2008-03-20 테바 파마슈티컬 인더스트리즈 리미티드 몬테루카스트 나트륨을 제조하는 방법
ATE500225T1 (de) 2004-07-19 2011-03-15 Matrix Lab Ltd Verfahren zur herstellung von montelukast und salzen davon
PL205637B1 (pl) * 2004-10-22 2010-05-31 Inst Farmaceutyczny Sposób wytwarzania kwasu (R,E)-(1-{1-{3-[2-(7-chlorochinolin-2-ylo)etenylo]fenylo}-3-[2-(1-hydroksy-1-metyloetylo)fenylo] propylosulfanylometylo}cyklopropylo)octowego i/lub jego farmaceutycznie dopuszczalnych soli
WO2006064269A2 (en) 2004-12-17 2006-06-22 Cipla Limited Salts of leukotriene antagonist montelukast
NZ556248A (en) * 2005-03-14 2010-06-25 Neurosearch As Pyrazolyl-quinazoline potassium channel modulating agents and their medical use
US20100168432A1 (en) * 2005-07-05 2010-07-01 Matrix Laboratories Ltd Process for the Preparation of Montelukast
US8178680B2 (en) * 2005-12-13 2012-05-15 Msn Laboratories Limited Process for the preparation of Montelukast and its pharmaceutically acceptable salts
WO2007096889A2 (en) * 2006-02-27 2007-08-30 Chemagis Ltd. Process for preparing montelukast and salts thereof
EP1886998A1 (en) * 2006-08-09 2008-02-13 Esteve Quimica, S.A. Purification process of montelukast and its amine salts
WO2008023044A1 (en) * 2006-08-23 2008-02-28 Sandoz Ag Process for the preparation of montelukast free acid and its amine salts
WO2008062478A2 (en) 2006-11-20 2008-05-29 Manne Satyanarayana Reddy Improved process for pure montelukast sodium through pure intermediates as well as novel amine salts
KR100774088B1 (ko) * 2006-12-14 2007-11-06 한미약품 주식회사 몬테루카스트의 제조방법 및 이에 사용되는 중간체
WO2008087628A1 (en) * 2007-01-15 2008-07-24 Chemagis Ltd. Process for preparing montelukast sodium containing controlled levels of impurities
KR101469015B1 (ko) * 2008-02-25 2014-12-05 주식회사 종근당 몬테루카스트의 제조방법 및 이에 사용되는 중간체

Also Published As

Publication number Publication date
JP5531018B2 (ja) 2014-06-25
CN102164897B (zh) 2013-04-17
US8426600B2 (en) 2013-04-23
JP2012503648A (ja) 2012-02-09
WO2010036048A3 (ko) 2010-08-19
US20110166356A1 (en) 2011-07-07
WO2010036048A2 (ko) 2010-04-01
KR101123292B1 (ko) 2012-03-19
KR20100035597A (ko) 2010-04-05
CN102164897A (zh) 2011-08-24

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Legal Events

Date Code Title Description
B08F Application fees: application dismissed [chapter 8.6 patent gazette]
B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]