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BR9812439A - Novas pirimidin-4-ona e pirimidin-4-tiona como fungicida - Google Patents

Novas pirimidin-4-ona e pirimidin-4-tiona como fungicida

Info

Publication number
BR9812439A
BR9812439A BR9812439-0A BR9812439A BR9812439A BR 9812439 A BR9812439 A BR 9812439A BR 9812439 A BR9812439 A BR 9812439A BR 9812439 A BR9812439 A BR 9812439A
Authority
BR
Brazil
Prior art keywords
alkyl
halogen
mono
alkoxy
unsubstituted
Prior art date
Application number
BR9812439-0A
Other languages
English (en)
Inventor
Harald Walter
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of BR9812439A publication Critical patent/BR9812439A/pt

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/48—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with two nitrogen atoms as the only ring hetero atoms
    • A01N43/54—1,3-Diazines; Hydrogenated 1,3-diazines
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/90—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having two or more relevant hetero rings, condensed among themselves or with a common carbocyclic ring system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C07D239/72—Quinazolines; Hydrogenated quinazolines
    • C07D239/86—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in position 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C07D239/72—Quinazolines; Hydrogenated quinazolines
    • C07D239/86—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in position 4
    • C07D239/88—Oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C07D239/72—Quinazolines; Hydrogenated quinazolines
    • C07D239/86—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in position 4
    • C07D239/88—Oxygen atoms
    • C07D239/90—Oxygen atoms with acyclic radicals attached in position 2 or 3
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C07D239/72—Quinazolines; Hydrogenated quinazolines
    • C07D239/86—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in position 4
    • C07D239/88—Oxygen atoms
    • C07D239/91—Oxygen atoms with aryl or aralkyl radicals attached in position 2 or 3
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C07D239/72—Quinazolines; Hydrogenated quinazolines
    • C07D239/86—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in position 4
    • C07D239/88—Oxygen atoms
    • C07D239/92—Oxygen atoms with hetero atoms directly attached to nitrogen atoms of the hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D333/28—Halogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D333/30—Hetero atoms other than halogen
    • C07D333/36—Nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Environmental Sciences (AREA)
  • Plant Pathology (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Dentistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Agronomy & Crop Science (AREA)
  • Zoology (AREA)
  • Pest Control & Pesticides (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

Abstract

Patente de Invenção: <B>"NOVAS PIRIMIDIN-4-ONA E PIRIMIDIN-4-TIONA COMO FUNGICIDA"<D>. Novos derivados do tipo pirimidin-4-ona e pirimidin-4-tiona de fórmula I onde A é fenila, tienila (incluindo todos os 3 isómeros), tiazolila, piridila ou piridazinila; X é oxigênio ou enxofre; R~ 1~ é hidrogênio, halogênio ou trimetilsilila; R~ 2~ é hidrogênio, halogênio ou trimetilsilila; pelo menos um de R~ 1~ e R~ 2~ é não é hidrogênio; R~ 3~ é C~ 1~-C~ 8~ alquila, C~ 1~-C~ 8~ alquenila, C~ 1~-C~ 8~ alquinila que são não-substituídas ou mono a trissubstituídas com C~ 3~-C~ 6~ cicloalquila, halogênio, C~ 1~-C~ 6~ alcóxi ou C~ 1~-C~ 6~ haloalcóxi; O-C~ 1~-C~ 6~ alquila, O-C~ 2~-C~ 6~ alquenila, O-C~ 2~-C~ 6~ alquinila, que são não-substituídas ou mono a trissubstituídas com C~ 3~-C~ 6~ cicloalquila, halogênio ou C~ 1~-C~ 6~ alcóxi; N-C~ 1~-C~ 6~ alquila; ou N=CHC~ 1~-C~ 6~ alquila; R~ 4~ é C~ 1~-C~ 8~ alquila, C~ 1~-C~ 8~ alquenila, C~ 1~-C~ 8~ alquinila que são não-substituídas ou mono a trissubstituídas com C~ 3~-C~ 6~ cicloalquila, halogênio, ciano, C~ 1~-C~ 6~ alcóxi ou C~ 1~-C~ 6~ haloalcóxi; C~ 1~-C~ 4~ alcóxi-C~ 1~-C~ 4~ alcóxi; C~ 1~-C~ 4~ alcóxi-C~ 1~-C~ 4~ alquiltio; nitro; -CO-C~ 1~-C~ 6~ alquila; C~ 3~-C~ 6~ cicloalquila; ou fenila, que é não-substituída ou mono a trissubstituída com halogênio, C~ 1~-C~ 6~ alquila, C~ 1~-C~ 6~ haloalquila, C~ 1~-C~ 6~ alcóxi, C~ 1~-C~ 6~ haloalcóxi, ciano, nitro, amino, mono- C~ 1~-C~ 6~ alquilamino, di-C~ 1~-C~ 6~ alquilamino, C~ 1~-C~ 6~ alquiltio, fenila ou fenóxi e onde a parte fenila é não-substituída ou mono a trissubstituída com halogênio, C~ 1~-C~ 6~ alquila, C~ 1~-C~ 6~ haloalquila, C~ 1~-C~ 6~ alcóxi ou C~ 1~-C~ 6~ haloalcóxi. Os novos compostos possuem propriedades protetoras de plantas e são adequados para proteger plantas contra infestação por microorganismos fitopatogênicos, em particular fungos.
BR9812439-0A 1997-09-12 1998-09-10 Novas pirimidin-4-ona e pirimidin-4-tiona como fungicida BR9812439A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9719411.2A GB9719411D0 (en) 1997-09-12 1997-09-12 New Pesticides
PCT/EP1998/005790 WO1999014202A2 (en) 1997-09-12 1998-09-10 Novel pyrimidin-4-one and pyrimidin-4-thione as fungicide

Publications (1)

Publication Number Publication Date
BR9812439A true BR9812439A (pt) 2000-09-26

Family

ID=10818960

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9812439-0A BR9812439A (pt) 1997-09-12 1998-09-10 Novas pirimidin-4-ona e pirimidin-4-tiona como fungicida

Country Status (26)

Country Link
US (1) US6277858B1 (pt)
EP (1) EP1015434B1 (pt)
JP (1) JP2001516749A (pt)
KR (1) KR100585571B1 (pt)
CN (1) CN1270593A (pt)
AR (1) AR015439A1 (pt)
AT (1) ATE216370T1 (pt)
AU (1) AU743717B2 (pt)
BR (1) BR9812439A (pt)
CA (1) CA2301694A1 (pt)
DE (1) DE69804981T2 (pt)
DK (1) DK1015434T3 (pt)
EG (1) EG22051A (pt)
ES (1) ES2175804T3 (pt)
GB (1) GB9719411D0 (pt)
GT (1) GT199800142A (pt)
HN (1) HN1998000139A (pt)
HU (1) HUP0002423A3 (pt)
IL (1) IL134779A0 (pt)
NZ (1) NZ503261A (pt)
PL (1) PL339053A1 (pt)
PT (1) PT1015434E (pt)
TR (1) TR200000713T2 (pt)
TW (1) TW429254B (pt)
WO (1) WO1999014202A2 (pt)
ZA (1) ZA988336B (pt)

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CN101622245B (zh) 2007-01-25 2014-09-10 纳幕尔杜邦公司 杀真菌酰胺
DE102007045920B4 (de) 2007-09-26 2018-07-05 Bayer Intellectual Property Gmbh Synergistische Wirkstoffkombinationen
US8349870B2 (en) 2008-01-25 2013-01-08 E I Du Pont De Nemours And Company Fungicidal hetercyclic compounds
CN101531638B (zh) * 2008-03-13 2011-12-28 中国科学院广州生物医药与健康研究院 用作雌激素相关受体调节剂的化合物及其应用
CN101628913B (zh) 2008-07-18 2013-01-23 中国科学院广州生物医药与健康研究院 用作雌激素相关受体调节剂的化合物及其应用
CN102227423B (zh) 2008-12-02 2015-06-17 纳幕尔杜邦公司 杀真菌杂环化合物
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Also Published As

Publication number Publication date
PL339053A1 (en) 2000-12-04
KR20010023894A (ko) 2001-03-26
ES2175804T3 (es) 2002-11-16
TW429254B (en) 2001-04-11
WO1999014202A3 (en) 1999-05-14
TR200000713T2 (tr) 2000-08-21
US6277858B1 (en) 2001-08-21
AU9742998A (en) 1999-04-05
EG22051A (en) 2002-06-30
DE69804981T2 (de) 2002-11-28
AU743717B2 (en) 2002-01-31
ATE216370T1 (de) 2002-05-15
PT1015434E (pt) 2002-08-30
EP1015434A2 (en) 2000-07-05
CN1270593A (zh) 2000-10-18
WO1999014202B1 (en) 1999-06-17
EP1015434B1 (en) 2002-04-17
IL134779A0 (en) 2001-04-30
DE69804981D1 (de) 2002-05-23
CA2301694A1 (en) 1999-03-25
ZA988336B (en) 1999-02-12
GT199800142A (es) 2000-03-02
AR015439A1 (es) 2001-05-02
HUP0002423A2 (hu) 2000-11-28
GB9719411D0 (en) 1997-11-12
KR100585571B1 (ko) 2006-06-02
NZ503261A (en) 2002-03-28
DK1015434T3 (da) 2002-08-05
HN1998000139A (es) 1999-06-02
JP2001516749A (ja) 2001-10-02
WO1999014202A2 (en) 1999-03-25
HUP0002423A3 (en) 2001-02-28

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