BR9800773A - Compostos de benzenossulfonilamina, processo para a preparação dos mesmos e composições farmacêuticas contendo os mesmos. - Google Patents
Compostos de benzenossulfonilamina, processo para a preparação dos mesmos e composições farmacêuticas contendo os mesmos.Info
- Publication number
- BR9800773A BR9800773A BR9800773-4A BR9800773A BR9800773A BR 9800773 A BR9800773 A BR 9800773A BR 9800773 A BR9800773 A BR 9800773A BR 9800773 A BR9800773 A BR 9800773A
- Authority
- BR
- Brazil
- Prior art keywords
- group
- optionally substituted
- hydrogen atom
- alkyl
- atom
- Prior art date
Links
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- KHBQMWCZKVMBLN-UHFFFAOYSA-N Benzenesulfonamide Chemical class NS(=O)(=O)C1=CC=CC=C1 KHBQMWCZKVMBLN-UHFFFAOYSA-N 0.000 title 1
- 125000000217 alkyl group Chemical group 0.000 abstract 5
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 5
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 229910052739 hydrogen Inorganic materials 0.000 abstract 2
- 239000001257 hydrogen Substances 0.000 abstract 2
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 2
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 2
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 125000003277 amino group Chemical group 0.000 abstract 1
- 125000004429 atom Chemical group 0.000 abstract 1
- 125000005843 halogen group Chemical group 0.000 abstract 1
- 125000004430 oxygen atom Chemical group O* 0.000 abstract 1
- 125000005415 substituted alkoxy group Chemical group 0.000 abstract 1
- 125000000547 substituted alkyl group Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
- C07C311/15—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings
- C07C311/16—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the sulfonamide groups bound to hydrogen atoms or to an acyclic carbon atom
- C07C311/19—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the sulfonamide groups bound to hydrogen atoms or to an acyclic carbon atom to an acyclic carbon atom of a hydrocarbon radical substituted by carboxyl groups
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
- C07C311/15—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings
- C07C311/21—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the sulfonamide groups bound to a carbon atom of a six-membered aromatic ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C381/00—Compounds containing carbon and sulfur and having functional groups not covered by groups C07C301/00 - C07C337/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2602/00—Systems containing two condensed rings
- C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
- C07C2602/04—One of the condensed rings being a six-membered aromatic ring
- C07C2602/10—One of the condensed rings being a six-membered aromatic ring the other ring being six-membered, e.g. tetraline
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
Abstract
Patente de Invenção:<B>"COMPOSTOS DE BENZENOSSULFONILAMINA, PROCESSO PARA A PREPARAçãO DOS MESMOS E COMPOSIçõES FARMACêUTICAS CONTENDO OS MESMOS"<D>. Composto da fórmula (I) na qual: R~ a~ e R~ b~, que podem ser idênticos ou diferentes, representam um átomo de hidrogênio ou um grupo alquila, ou alternativamente R~ a~ e R~ b~ em conjunto formam uma ligação, R~ c~ representa um grupo hidroxila, um grupo alcóxi opcionalmente substituído ou um grupo amino opcionalmente substituído, R~ 1~ representa um átomo de hidrogênio ou um grupo -O-NO~ 2~, -O-NO ou -S-NO, R~ 2~ e R~ 3~, que podem ser idênticos ou diferentes, representam um átomo de hidrogênio, um grupo alquila ou um grupo fenila opcionalmente substituído, X representa um átomo de oxigênio ou um grupo -NH-CO-, m representa 0 ou 1, n representa um núero inteiro tal como 0 <243> n <243> 6, p representa 0 ou 1, R~ 4~ representa um átomo de hidrogênio, um grupo alquila opcionalmente substituído, um grupo fenila opcionalmente substituído ou um grupo como definido na descrição, R~ 5~ representa um átomo de hidrogênio ou um grupo alquila, R~ 6~ representa um átomo de hidrogênio ou um grupo alquila, ou de forma alternativa R~ 5~ e R~ 6~ em conjunto formam uma cadeia -(CH~ 2~)~ t~- na qual t representa 1 ou 2, q representa 0, 1 ou 2, r representa um número inteiro tal como o <243> n <243> 6, R~ d~ e R~ e~, que podem ser idênticos ou diferentes, representam um átomo de hidrogênio ou halogênio ou um grupo alquila, alcóxi, hidroxila ou trialo-alquila, ficando entendido que pelo menos um grupo -O-NO~ 2~, -O-NO ou -S-NO está presenta em R~ 1~, R~ 4~ ou R~ c~.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR9702445A FR2760235B1 (fr) | 1997-02-28 | 1997-02-28 | Nouveaux derives de benzenesulfonylamine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR9800773A true BR9800773A (pt) | 1999-12-07 |
Family
ID=9504314
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR9800773-4A BR9800773A (pt) | 1997-02-28 | 1998-02-26 | Compostos de benzenossulfonilamina, processo para a preparação dos mesmos e composições farmacêuticas contendo os mesmos. |
Country Status (20)
| Country | Link |
|---|---|
| US (1) | US6013667A (pt) |
| EP (1) | EP0864561B1 (pt) |
| JP (1) | JP3917287B2 (pt) |
| CN (1) | CN1160323C (pt) |
| AT (1) | ATE205189T1 (pt) |
| AU (1) | AU736532B2 (pt) |
| BR (1) | BR9800773A (pt) |
| CA (1) | CA2231026C (pt) |
| DE (1) | DE69801535T2 (pt) |
| DK (1) | DK0864561T3 (pt) |
| ES (1) | ES2163844T3 (pt) |
| FR (1) | FR2760235B1 (pt) |
| GR (1) | GR3037048T3 (pt) |
| HK (1) | HK1014932A1 (pt) |
| HU (1) | HU224960B1 (pt) |
| NO (1) | NO310068B1 (pt) |
| NZ (1) | NZ329868A (pt) |
| PL (1) | PL193930B1 (pt) |
| PT (1) | PT864561E (pt) |
| ZA (1) | ZA981681B (pt) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2803848B1 (fr) * | 2000-01-19 | 2002-02-15 | Adir | Nouveaux derives de benzenesulfonamide, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
| FR2827280B1 (fr) * | 2001-07-13 | 2003-10-31 | Servier Lab | Nouveaux derives de benzene sulfonamide, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
| US8152693B2 (en) | 2006-05-08 | 2012-04-10 | Nokia Corporation | Exercise data device, server, system and method |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3000377A1 (de) * | 1980-01-07 | 1981-07-09 | Boehringer Mannheim Gmbh, 6800 Mannheim | Neue sulfonamide, verfahren zu deren herstellung sowie diese verbindungen enthaltende arzneimittel |
| ATE138645T1 (de) * | 1991-03-01 | 1996-06-15 | Zeria Pharm Co Ltd | Indan-derivate als thromboxan-antagonisten |
| JPH08503484A (ja) * | 1992-11-27 | 1996-04-16 | ビイク ネダーラント ベスローテン フェンノートシャップ | 調剤学的特性を有するニトロキシ化合物 |
| FR2711139B1 (fr) * | 1993-10-15 | 1995-12-01 | Adir | Nouveaux dérivés de 1,2,3,4-tétrahydronaphtalène, leur procédé de préparation et les compositions pharmaceutiques qui les contiennent. |
-
1997
- 1997-02-28 FR FR9702445A patent/FR2760235B1/fr not_active Expired - Fee Related
-
1998
- 1998-02-26 CA CA002231026A patent/CA2231026C/fr not_active Expired - Fee Related
- 1998-02-26 BR BR9800773-4A patent/BR9800773A/pt active Search and Examination
- 1998-02-26 JP JP04479498A patent/JP3917287B2/ja not_active Expired - Fee Related
- 1998-02-27 PL PL325082A patent/PL193930B1/pl not_active IP Right Cessation
- 1998-02-27 PT PT98400468T patent/PT864561E/pt unknown
- 1998-02-27 AT AT98400468T patent/ATE205189T1/de active
- 1998-02-27 NZ NZ329868A patent/NZ329868A/xx not_active IP Right Cessation
- 1998-02-27 US US09/032,587 patent/US6013667A/en not_active Expired - Lifetime
- 1998-02-27 DE DE69801535T patent/DE69801535T2/de not_active Expired - Lifetime
- 1998-02-27 AU AU56360/98A patent/AU736532B2/en not_active Ceased
- 1998-02-27 ES ES98400468T patent/ES2163844T3/es not_active Expired - Lifetime
- 1998-02-27 EP EP98400468A patent/EP0864561B1/fr not_active Expired - Lifetime
- 1998-02-27 CN CNB981080707A patent/CN1160323C/zh not_active Expired - Fee Related
- 1998-02-27 DK DK98400468T patent/DK0864561T3/da active
- 1998-02-27 NO NO980842A patent/NO310068B1/no not_active IP Right Cessation
- 1998-02-27 ZA ZA981681A patent/ZA981681B/xx unknown
- 1998-02-27 HU HU9800430A patent/HU224960B1/hu not_active IP Right Cessation
-
1999
- 1999-01-07 HK HK99100054A patent/HK1014932A1/xx not_active IP Right Cessation
-
2001
- 2001-10-30 GR GR20010401920T patent/GR3037048T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP0864561A1 (fr) | 1998-09-16 |
| HU224960B1 (en) | 2006-04-28 |
| PL325082A1 (en) | 1998-08-31 |
| PT864561E (pt) | 2001-12-28 |
| ZA981681B (en) | 1998-09-04 |
| CA2231026A1 (fr) | 1998-08-28 |
| NZ329868A (en) | 1999-01-28 |
| AU5636098A (en) | 1998-09-03 |
| ATE205189T1 (de) | 2001-09-15 |
| DE69801535D1 (de) | 2001-10-11 |
| CN1195662A (zh) | 1998-10-14 |
| CN1160323C (zh) | 2004-08-04 |
| DE69801535T2 (de) | 2002-05-08 |
| JPH10251217A (ja) | 1998-09-22 |
| CA2231026C (fr) | 2004-02-10 |
| EP0864561B1 (fr) | 2001-09-05 |
| HUP9800430A2 (hu) | 1999-06-28 |
| FR2760235A1 (fr) | 1998-09-04 |
| HK1014932A1 (en) | 1999-10-08 |
| NO980842D0 (no) | 1998-02-27 |
| HU9800430D0 (en) | 1998-04-28 |
| GR3037048T3 (en) | 2002-01-31 |
| PL193930B1 (pl) | 2007-04-30 |
| DK0864561T3 (da) | 2001-11-19 |
| US6013667A (en) | 2000-01-11 |
| NO310068B1 (no) | 2001-05-14 |
| HUP9800430A3 (en) | 2000-09-28 |
| AU736532B2 (en) | 2001-08-02 |
| NO980842L (no) | 1998-08-31 |
| ES2163844T3 (es) | 2002-02-01 |
| JP3917287B2 (ja) | 2007-05-23 |
| FR2760235B1 (fr) | 1999-04-09 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PC | Transfer |
Free format text: LES LABORATOIRES SERVIER (FR) |
|
| B06A | Patent application procedure suspended [chapter 6.1 patent gazette] | ||
| B07A | Application suspended after technical examination (opinion) [chapter 7.1 patent gazette] | ||
| B09B | Patent application refused [chapter 9.2 patent gazette] |
Free format text: INDEFIRO O PRESENTE PEDIDO, UMA VEZ QUE O MESMO NAO ESTA DE ACORDO COM OS ARTIGOS 8, 13, 24 E 25 DA LPI. |
|
| B12B | Appeal against refusal [chapter 12.2 patent gazette] | ||
| B07E | Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette] | ||
| B11D | Dismissal acc. art. 38, par 2 of ipl - failure to pay fee after grant in time |